Journal of Pediatric Hematology-Oncology Nursing最新文献_第3页

Dinutuximab-Associated Neurotoxicity: Incidence, Presentation, Risk Factors, and Nursing Interventions. 地努妥昔单抗相关神经毒性：发生率、表现、危险因素和护理干预。

IF 1.6 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-03-01 Epub Date: 2026-02-18 DOI: 10.1177/27527530251398474

Kristen L Dalton, Erin A Armideo, Shannon L Markert, Clifton P Thornton

{"title":"Dinutuximab-Associated Neurotoxicity: Incidence, Presentation, Risk Factors, and Nursing Interventions.","authors":"Kristen L Dalton, Erin A Armideo, Shannon L Markert, Clifton P Thornton","doi":"10.1177/27527530251398474","DOIUrl":"10.1177/27527530251398474","url":null,"abstract":"BackgroundDinutuximab, a GD2-directed monoclonal antibody, is now incorporated into therapy for high-risk and relapsed or refractory neuroblastoma. Despite its boxed warning for drug-induced neurotoxicity, little is known about the incidence, risk factors, monitoring guidelines, or management of this spectrum of adverse neurologic effects. This study aimed to describe neurotoxicity symptoms, summarize nursing-related interventions, and evaluate potential risk factors for neurotoxicity.MethodThis retrospective descriptive study reviewed 437 dinutuximab cycles administered to 65 patients between 2018 and 2023. Data on patient demographics and clinical variables, occurrence of 11 potential distinct neurotoxicities, and nursing responses were analyzed to describe the sample and evaluate for differences and associations between variables.ResultsNeurotoxicity occurred in 159 (36.4%) cycles, affecting 83.1% of participants without relation to age or sex. Neurotoxicities encompassed nine separate symptoms and typically included urinary retention (66.2% of neurotoxic cycles) and visual changes (16.9% of neurotoxic cycles). Symptoms appeared on day 1 in 73.7% of cycles. Neurotoxicity was unrelated to dinutuximab use in upfront versus relapsed therapy (OR = 1.20, p = .484) or Curie score (OR = 1.0, p = .883). A total of 11 nursing interventions were identified and ranged from calling a code (0.46% of all cycles) to additional medication administration (29.5% of all cycles).DiscussionDinutuximab-associated neurotoxicity is common and appears early in treatment. Findings suggest patients may be universally at risk for toxicity with relation to demographics or clinical factors. Targeted neurologic monitoring and nursing interventions are needed for safe administration and should be developed and tested.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"83-91"},"PeriodicalIF":1.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rapid Review of Supportive Care Management of Treatment-Related Acute and Long-Term Cardiac Toxicities in Children with Cancer and Childhood Cancer Survivors Who Have Received Tyrosine Kinase Inhibitors (TKIs). 对接受酪氨酸激酶抑制剂（TKIs）治疗的儿童癌症和儿童癌症幸存者的治疗相关急性和长期心脏毒性的支持治疗管理的快速回顾

IF 1.6 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-03-01 Epub Date: 2026-02-19 DOI: 10.1177/27527530251398437

Beth Fisher, Mary Keller, Nancy Dias, Verna Hendricks-Ferguson, Rebecca Smith, Savannah Horvick, Constance N Owen, Jennifer Tiller, Katherine Smith

{"title":"A Rapid Review of Supportive Care Management of Treatment-Related Acute and Long-Term Cardiac Toxicities in Children with Cancer and Childhood Cancer Survivors Who Have Received Tyrosine Kinase Inhibitors (TKIs).","authors":"Beth Fisher, Mary Keller, Nancy Dias, Verna Hendricks-Ferguson, Rebecca Smith, Savannah Horvick, Constance N Owen, Jennifer Tiller, Katherine Smith","doi":"10.1177/27527530251398437","DOIUrl":"10.1177/27527530251398437","url":null,"abstract":"BackgroundAdvances in targeted cancer therapies have transformed the management of pediatric malignancies. Tyrosine kinase inhibitors (TKIs), a specific class of targeted agents, inhibit signaling pathways essential to cancer cell survival. TKIs have improved outcomes in specific pediatric cancers. However, TKIs are associated with acute and long-term cardiotoxicities. Supportive care management aimed at prevention, early detection, and timely intervention is necessary to mitigate cardiotoxicity associated with TKIs.MethodThis rapid review examined the supportive care management used in children with cancer and childhood cancer survivors who received TKIs as part of their treatment. TKIs were selected due to their frequent use in pediatric oncology. Eligible studies, published between 2019 and 2025, included patients aged 0-21 years. From 206 citations, 30 duplicates were removed, and 176 records were screened in Rayyan. Fifteen full texts were reviewed, and two additional studies were hand-searched, yielding eight studies for inclusion. Data extraction, synthesis, and PRISMA documentation were completed collaboratively by the review team.ResultsFive key categories in supportive care management emerged: surveillance strategies, preventive strategies, cardiac medication use, collaboration between pediatric oncology and cardiology, and transition of care for childhood cancer survivors.ConclusionTKIs are associated with significant cardiotoxic risk in pediatric oncology. This review identified five supportive care categories that may inform future interdisciplinary research and guide the development of evidence-based supportive care recommendations aimed at optimizing cardiovascular outcomes in this patient population.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"114-124"},"PeriodicalIF":1.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146228953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gene Therapy for Sickle Cell Disease. 镰状细胞病的基因治疗

IF 1.6 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-03-01 Epub Date: 2026-01-19 DOI: 10.1177/27527530251400731

Colleen H Dansereau

{"title":"Gene Therapy for Sickle Cell Disease.","authors":"Colleen H Dansereau","doi":"10.1177/27527530251400731","DOIUrl":"10.1177/27527530251400731","url":null,"abstract":"BackgroundSickle cell disease (SCD) is a genetic blood disorder in which sickled red blood cells cannot easily pass through the vasculature, leading to impaired tissue perfusion and oxygenation that can lead to vaso-occlusive pain, stroke, and multiorgan and tissue damage. Scientists have now developed genetic approaches to treating SCD with a curative intent. The purpose of this article is to inform the reader of the current state of SCD gene therapy and an institution's experience and outcomes with this therapy.MethodGene therapy uses the patient's stem cells to create a patient-specific genetically modified product to correct or replace the genetic mutation causing the SCD. The two genetic treatment approaches to SCD gene therapy are gene addition/gene transfer and gene editing. Patients experience a multistep, complex process to undergo this treatment, requiring close communication between the patient and the interdisciplinary teams at the patient's home treatment center and gene therapy treatment site. Phase I, II, and III clinical trials have been completed or are ongoing worldwide.ResultsBased on clinical trial findings, in 2023, the Food and Drug Administration approved two gene therapy products. At one treatment site, 17 patients have completed treatment on two clinical trials, and all are alive and stable without serious adverse events related to the gene therapy product.DiscussionAs gene therapy treatments continue to develop as an SCD treatment option, nurses play an important role in educating patients and their families about the therapy. Patients undergoing gene therapy need close nursing care coordination and expert supportive care during all steps of the treatment process, including follow-up.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"106-113"},"PeriodicalIF":1.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial. 社论。

IF 1.5 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-03-01 Epub Date: 2026-03-07 DOI: 10.1177/27527530261416704

Janice S Withycombe, Elizabeth A Duffy

引用次数: 0

Precision-Based Care: A Multidisciplinary Approach. 精准护理：多学科方法。

IF 1.6 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-03-01 Epub Date: 2026-03-31 DOI: 10.1177/27527530261426262

Belinda N Mandrell, Liza-Marie Johnson, Jami S Gattuso, Stacey Hines-Dowell, Sheri Ring, Kristine R Crews, Cyrine E Haidar, Katianne M Howard-Sharp, Kim E Nichols

{"title":"Precision-Based Care: A Multidisciplinary Approach.","authors":"Belinda N Mandrell, Liza-Marie Johnson, Jami S Gattuso, Stacey Hines-Dowell, Sheri Ring, Kristine R Crews, Cyrine E Haidar, Katianne M Howard-Sharp, Kim E Nichols","doi":"10.1177/27527530261426262","DOIUrl":"10.1177/27527530261426262","url":null,"abstract":"BackgroundPrecision-based approaches are reshaping healthcare by tailoring assessments and therapies to a patient's individual needs. To ensure nursing remains integral to this evolving landscape, active collaboration with multidisciplinary teams is essential. Nurses must understand the clinical implications of genomic testing, be provided educational opportunities, and understand the patient and parent perspectives of precision-based care. Thus, the nurse is empowered to translate research into advancing patient-centered care.ObjectiveThis review presents our multidisciplinary team's approach to understanding the educational needs of nurses and physicians, as well as patient and parent perspectives of precision-based care, along with key nursing considerations.MethodThis is a process paper describing one institution's journey through in-depth inquiries identifying knowledge gaps related to genomic testing of tumor and germline tissues, consenting, pharmacogenetics, and gene therapy. We also explored expectations held by patients and their families surrounding testing and return of results.ResultsOur findings offer key insights, including the need for education of healthcare providers, equitable patient education and access to pharmacogenomic and cancer genomic testing, ethical complexities within the consenting process, and perspectives from parents and patients on clinical genomics and gene therapy for sickle cell disease.ConclusionThe findings from this institution's efforts may help guide or inform other institutions working to deliver precision-based oncology and hematology care. Nurses must be equipped with expertise to advocate effectively for patients and families. In doing so, they can guide them through the opportunities and challenges of precision-based care.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"75-82"},"PeriodicalIF":1.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nurses' Experiences in Assessing and Promoting Optimal Nutrition During Pediatric Cancer Treatment: A Qualitative Study. 儿童癌症治疗过程中护士评估和促进最佳营养的经验：一项定性研究。

IF 1.5 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-13 DOI: 10.1177/27527530251392115

Håkon Endal, Gabriele Kitzmüller, Inger J Danielsen, Inger Pauline Landsem

{"title":"Nurses' Experiences in Assessing and Promoting Optimal Nutrition During Pediatric Cancer Treatment: A Qualitative Study.","authors":"Håkon Endal, Gabriele Kitzmüller, Inger J Danielsen, Inger Pauline Landsem","doi":"10.1177/27527530251392115","DOIUrl":"https://doi.org/10.1177/27527530251392115","url":null,"abstract":"BackgroundChildhood cancer often entails long-term treatment, with various side effects that affect the nutritional status of patients. Nurses play a pivotal role in assessing and promoting nutritional support. Therefore, we aimed to explore the experiences of clinical nurses assessing and promoting optimal nutrition supportive care during pediatric cancer treatment.MethodFour focus groups involving 22 clinical nurses were conducted at the four tertiary hospitals in Norway treating children with cancer. Analysis was guided by Braun and Clarke's reflexive thematic approach. The study adhered to the consolidated criteria for reporting qualitative research.ResultsFour themes were created. Nurses employed a holistic approach to plan and integrate nutritional care in collaboration with families, dietitians, doctors, and other professionals. Barriers in nutritional oncology care identified were treatment side effects, time constraints, and inadequate use of guidelines. Nurses experienced difficulties discussing overweight conditions with patients.DiscussionOur study offers insight into the importance of close collaboration with every single family, thus promoting family-centered care for assessing and promoting optimal nutritional status during treatment for pediatric oncology. Nurses must have a broad perspective on what constitutes optimal nutritional care. Using guidelines in a systematic manner is crucial to prevent malnutrition during childhood cancer treatment.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":"43 1","pages":"36-47"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145744894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Interpreter Use for Patients With Non-English Language Preference in a Pediatric Center for Cancer and Blood Disorders. 在癌症和血液疾病儿科中心加强对非英语语言偏好患者的口译使用。

IF 1.5 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-01-01 Epub Date: 2025-11-26 DOI: 10.1177/27527530251381782

Carolyn Kass, Jeanne Little

{"title":"Enhancing Interpreter Use for Patients With Non-English Language Preference in a Pediatric Center for Cancer and Blood Disorders.","authors":"Carolyn Kass, Jeanne Little","doi":"10.1177/27527530251381782","DOIUrl":"10.1177/27527530251381782","url":null,"abstract":"BackgroundIneffective interpretation leads to delayed diagnoses and treatment plans and patient dissatisfaction.MethodA guideline was developed for a center for cancer and blood disorders unit to improve interpretation services for patients and families with non-English language preference (NELP), signage was installed to adequately identify interpretation needs, video remote interpreter (VRI) devices were purchased for the unit, and patients and families were prompted daily to monitor if interpretation services had been used. Adherence to interpreter use was tracked via documentation in the electronic health record.ResultsThere was a 59% increase in interpreter use for patients and families with NELP. The National Research Corporation Health Discharge Survey conducted for patients with NELP demonstrated a 6% improvement in questions regarding communication and input in their care while in the hospital.DiscussionThe continual increase in documentation of interpreter use for patients with NELP over a 12-month period alludes to the sustainability of this project. The multipronged approach allowed for patients with NELP to have increased access and contact with interpreters, which translated to improved patient and caregiver perception of communication with their medical team and increased input in their medical care.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"59-65"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145606689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Mixed-Methods Study to Explore Healthcare Utilization Among Children and Adolescents With Sickle Cell Disease During the COVID-19 Pandemic. COVID-19大流行期间镰状细胞病儿童和青少年医疗保健利用的混合方法研究

IF 1.5 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-03 DOI: 10.1177/27527530251395716

Andrea Nowlin, Diana Ross, Kristina W Lai, Grace Kalmus, Lindsey Abel, Alexander Maillis, Pat Waters, Beatrice Gee, Peter A Lane, Brooke Cherven

{"title":"A Mixed-Methods Study to Explore Healthcare Utilization Among Children and Adolescents With Sickle Cell Disease During the COVID-19 Pandemic.","authors":"Andrea Nowlin, Diana Ross, Kristina W Lai, Grace Kalmus, Lindsey Abel, Alexander Maillis, Pat Waters, Beatrice Gee, Peter A Lane, Brooke Cherven","doi":"10.1177/27527530251395716","DOIUrl":"10.1177/27527530251395716","url":null,"abstract":"BackgroundThe purpose of this study was to explore healthcare utilization among children with sickle cell disease (SCD) during the COVID-19 pandemic using a concurrent mixed-methods study design.Method and SampleTrends in healthcare encounters were examined across the institutional SCD population from September 2019 through February 2021. A convenience sample of children with SCD (8-17 years of age) and their parent/caregiver completed the COVID-19 Exposure and Family Impact Scale and a semistructured interview. Patients were eligible if they had a history of high hospital utilization (HHU; ≥5 admissions in 2019) or moderate HHU (MODHU; ≥2 ED visits or 2-4 admissions in 2019). Differences in outcomes by HHU status were assessed using Fisher's exact and Wilcoxon rank sum tests. Qualitative data were analyzed using thematic analysis.ResultsAcross the institutional SCD population (N = 2,153), healthcare encounters decreased in the early pandemic, returning close to baseline mid-pandemic. The sample (N = 16) was 75% (n = 12) male, 50% (n = 8) HHU, and median age 13.1 years; all parent participants were mothers. The MODHU group reported a more negative impact of COVID-19 on family functioning compared with the HHU group (p = .03), while distress was similarly high across both groups. Parents believed reduced exposure to infection, greater control over environmental triggers, and management of pain at home resulted in fewer healthcare visits. Parents described child distress as related to social isolation and virtual school.ConclusionWith reduced exposure to illness triggers, healthcare utilization for children with SCD decreased during the pandemic, although social isolation was associated with distress.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"5-14"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Illness Impact Perception, Positive Emotions, Hope, and Social Support Among Children With Cancer and Their Parents. 癌症儿童及其父母的疾病影响感知、积极情绪、希望和社会支持。

IF 1.5 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-03 DOI: 10.1177/27527530251381701

Irit Schwartz-Attias, Tamar Krulik, Ilan Roziner, Tammie Ronen

{"title":"Illness Impact Perception, Positive Emotions, Hope, and Social Support Among Children With Cancer and Their Parents.","authors":"Irit Schwartz-Attias, Tamar Krulik, Ilan Roziner, Tammie Ronen","doi":"10.1177/27527530251381701","DOIUrl":"10.1177/27527530251381701","url":null,"abstract":"BackgroundStudies show that in families with a child diagnosed with cancer, higher parental stress is associated with greater psychosocial difficulties in children. This study examined whether children with cancer and their parents can maintain a high positivity ratio (more positive than negative emotions) during illness, highlighting the mediating role of parental illness perception in the relationship between hope, social support, and positivity ratio in both parents and children.MethodThe study included 108 parent-child dyads (N = 216), where children (ages 7-18) were undergoing cancer treatment. Participants completed self-reports on hope, social support, and positive/negative affect. Parents also reported their perceived impact of the illness. Descriptive statistics and Pearson correlations were performed using IBM SPSS Statistics (Version 29). The theoretical research model was analyzed through structural equation modeling using Mplus (Version 8.6).ResultsDespite the challenges of illness, both children and their parents were found to maintain a high positivity ratio. Path analysis indicated that parents' perception of illness impact mediated the relationship between parents' social support and hope and the positivity ratio of both parents and children. Additionally, intergenerational correlations were found for social support and between parents' illness perceptions and children's positivity ratio.DiscussionThese findings highlight the crucial role of positive emotions during times of distress and offer valuable insights for developing targeted intervention programs aimed at supporting emotional resilience in children with cancer and their parents.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"23-35"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Oncology/Hematology Telephone Triage Toolkit for Children and Young People: A Linguistic Validation. 儿童和青少年肿瘤/血液学电话分类工具包：语言验证。

IF 1.5 4区医学

Journal of Pediatric Hematology-Oncology Nursing Pub Date : 2026-01-01 Epub Date: 2025-11-25 DOI: 10.1177/27527530251381676

Anna Bergadano, Letizia Borello, Francesca Resente, Pierpaolo Chialvo, Matteo Amicucci, Elena Rostagno, Enrica Rosa Lucia Castelletto, Antonella Longo, Andrea Zibaldo, Laura Odetto

{"title":"The Oncology/Hematology Telephone Triage Toolkit for Children and Young People: A Linguistic Validation.","authors":"Anna Bergadano, Letizia Borello, Francesca Resente, Pierpaolo Chialvo, Matteo Amicucci, Elena Rostagno, Enrica Rosa Lucia Castelletto, Antonella Longo, Andrea Zibaldo, Laura Odetto","doi":"10.1177/27527530251381676","DOIUrl":"10.1177/27527530251381676","url":null,"abstract":"BackgroundThe transition from hospital to home care in pediatric hematology/oncology brings important benefits for families, but it can also generate anxiety regarding the management of symptoms at home. Although hospitals offer 24/7 telephone support, there is currently no standardized telephone triage tool in Italy for pediatric hematology/oncology, resulting in variability in inconsistent practices. This study aims to carry out the linguistic validation in Italian of the \"Oncology/Hematology Telephone Triage Toolkit for Children and Young People V2 (2020),\" a tool designed to standardize and improve the telephone triage process.MethodAfter obtaining approval from the tool's authors, the linguistic validation process was developed in 10 steps, according to international guidelines: After forward and backward translation, a preliminary version was created and evaluated through the Item and Scale Content Validity Indices to obtain an Italian version of the tool.ResultsThe working group of native-speaking professionals and a panel of nine experts from various Italian hematology and oncology institutions reviewed and approved the translation, achieving item content validity scores between 0.8 and 1 and scale content validity scores between 0.88 and 1. Some linguistic adjustments were made to adapt terms to the Italian context while maintaining the original meaning. The final Italian version preserved the original meaning and was deemed conceptually equivalent to the source tool.DiscussionA validated methodology in the translation and validation process successfully adapted the tool to the Italian context, maintaining its content and design. The final Italian version is now ready for usability testing.","PeriodicalId":29692,"journal":{"name":"Journal of Pediatric Hematology-Oncology Nursing","volume":" ","pages":"15-22"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145606729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0