Coordination Chemistry Reviews最新文献

{"title":"Recent advancements in the multifaceted biomedical efficacy of triazole based metal complexes","authors":"Aman Kumar ,&nbsp;Seema Devi ,&nbsp;Sanjeev Kumar ,&nbsp;Kashmiri Lal","doi":"10.1016/j.ccr.2025.216675","DOIUrl":"10.1016/j.ccr.2025.216675","url":null,"abstract":"<div><div>In the last two decades, complexes of <em>N</em>-heterocycles especially of 1,2,3- and 1,2,4-triazoles have attracted the researcher's attention most due to their easier synthetic access and tremendous potential in several fields including catalysis, agricultural science, materials science, medicinal chemistry, photochemistry, <em>etc.</em> As triazoles played an important role in the modern era drug development but the discovery of their metal complexes with superior efficacy towards various diseases changed the course of medication development. Triazoles and their metal complexes were found to possess unique physicochemical properties important for rational drug designing. The high stability, easy synthesis, and ability to show various interactions with biological targets prompted the medicinal chemists to develop new triazole based metal complexes with better therapeutic efficacy and novel mode of action. In this review, we have summarized multifaceted biomedical efficacy of triazole based metal complexes in terms of their antimicrobial, antidiabetic, anticancer, antimalarial, antioxidant, anti-HIV, <em>etc.</em>, activities. This comprehensive review will provide important insights into triazole based metal complexes and their most intriguing biological potential thereby stimulating future research for the development of lead molecules.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216675"},"PeriodicalIF":20.3,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143817144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro and in vivo bioimaging by Quinoline conjugated probes and dyes","authors":"Avijit Ghosh ,&nbsp;Arghya Adhikary","doi":"10.1016/j.ccr.2025.216654","DOIUrl":"10.1016/j.ccr.2025.216654","url":null,"abstract":"<div><div>Bioimaging has emerged as an admirable technique for the early-stage detection of diseases that are difficult to drive backwards in the advanced stages, such as cancer and Alzheimer's disease. It provides a non-invasive approach for gathering information on the progress or reoccurrence of these diseases. However, smart fluorescent dyes are essential for bioimaging, allowing real-time visualization and tracking of biological processes. Fluorescent dyes or fluorophores absorb and emit light at two different wavelengths to generate fluorescence. They predominantly belong to small organic molecules and remain indispensable tools in scientific research. The most widely employed organic dyes in bioimaging applications are rhodamine, coumarin, fluorescein, cyanine, resorufin, BODIPY, quinoline, and Alexa Fluor dyes. Among them, quinoline-conjugated probes and dyes offer several advantages for bioimaging due to their unique structural and photophysical properties. Their tunable fluorescence properties, environmental sensitivity, enhanced photostability, NIR emission, high quantum yields, selective targeting, binding ability, minimal cytotoxicity, and versatility in sensing mechanisms provide unique advantages in multiplex imaging. Besides, fluorescent labelling with several traditional dyes significantly impacts the parent biological properties. However, such adverse effects are less experienced with quinoline dyes due to their excellent biocompatibility. In addition, cationic quinoline conjugates have been found to improve water solubility and mitochondria targeting ability. Therefore, they become excellent choices for imaging purposes. Moreover, quinoline-based probes show excellent molecular recognition properties. Scientists have highlighted their sensing abilities recently but have not adequately emphasized their imaging capabilities. Herein, we have comprehensively discussed almost 170 quinoline-conjugated molecules for their in vitro and in vivo imaging applications. We have confined our discussion to quinoline conjugates that are capable of bioimaging. Significantly, quinoline moiety plays an important role in these conjugates to improve their bioimaging performance. Appropriately, we have carefully classified these probes and dyes according to the role played by the quinoline unit. This will provide an important vision of using quinoline moiety to improve the performance of newly designed molecules for bioimaging applications. We hope this review will encourage researchers and young scientists to develop new generation quinoline conjugated dyes with superior bioimaging ability in the future.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216654"},"PeriodicalIF":20.3,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143817142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the nanoscale: Exploring quantum dot architectures on nanosheets and nanotubes for efficient hydrogen production","authors":"Anto Priyanka E ,&nbsp;Albin Shibu ,&nbsp;Sanjay Martin Kujur ,&nbsp;J. Judith Vijaya","doi":"10.1016/j.ccr.2025.216682","DOIUrl":"10.1016/j.ccr.2025.216682","url":null,"abstract":"<div><div>As we delve into the nanoscale realm, exploring nanostructures has unveiled a fascinating interplay between morphology and function. The intricate architecture of nanomaterials plays a vital role in determining their optical and electronic properties. 0-, 1- and 2-dimensional materials each possess unique features that arise from quantum confinement effects, distinct surface-to-volume ratios and other dimensional restrictions that influence their nanoscale behaviour. This offers a powerful tool for designing advanced catalysts with optimized performance. The global community's intensified commitment to decarbonization and transition toward sustainable energy systems has made carbon-neutral green hydrogen fuels a pivotal focus of innovation and investment. The strategic design of catalysts is crucial for optimizing water-splitting processes. We present a comprehensive review of the latest advancements in tailoring the structure and performance of nanotubes and nanosheets by forming heterojunctions with quantum dots, exploring their synergistic effects and exciting potential for efficient and sustainable hydrogen production. The fundamental need, diverse approaches and mechanistic aspects of water splitting are addressed herein. Further, the future challenges and opportunities in catalyst design for hydrogen evolution are explored. This state-of-the-art review offers insights into the development of highly efficient, specifically engineered catalysts for hydrogen production.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216682"},"PeriodicalIF":20.3,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral effect promotes single-atom catalysis","authors":"Yicong Chai ,&nbsp;Fenfei Wei ,&nbsp;Liru Cao ,&nbsp;Xiaodong Wang ,&nbsp;Sen Lin ,&nbsp;Jian Lin ,&nbsp;Tao Zhang","doi":"10.1016/j.ccr.2025.216649","DOIUrl":"10.1016/j.ccr.2025.216649","url":null,"abstract":"<div><div>Single-atom catalyst (SAC) attracts extensive interest in heterogeneous catalysis. Although single metal atoms (M₁) can serve as the dominant active site, growing evidences reveal that the directly coordinated heteroatoms usually determine the geometric and electronic structure of single-atom center. However, the impact of the peripheral environment, not bonded to M₁, is in its infancy while plays a significant role. In this review, we survey the recent progresses of optimizing SAC performance through modulation of the peripheral species, either by influencing the main M₁ center or serving as additional active site. Firstly, we introduce the basic principles of single-atom catalysis and the role of the peripheral environment in modifying catalytic behaviors. It is proposed that the single-atom site constitutes an active domain with the microenvironment, and the regulation of peripheral species within this active domain can effectively improve the catalytic performance. Subsequently, the design strategies and characterizations of peripheral environment are summarized. The peripheral effects on thermal, electro-, photo-catalysis and the underlying reaction mechanisms are then elucidated. Finally, the challenges and future prospects regarding the involvement of peripheral species in SAC are put forward. This review underscores the significance of the peripheral environment in SAC, which can provide important implications for the enhancement of catalysis through peripheral dopant engineering.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216649"},"PeriodicalIF":20.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of KBe2BO3F2-like second-order nonlinear optical materials and their structure-performance relationships","authors":"Junben Huang,&nbsp;Chenglong Zhang,&nbsp;Siying Chen,&nbsp;Ailijiang Abudurusuli","doi":"10.1016/j.ccr.2025.216632","DOIUrl":"10.1016/j.ccr.2025.216632","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Nonlinear optical (NLO) materials have attracted widespread attention since they can greatly expand the spectral range of the laser output through second harmonic generation (SHG). Recently, employing advantageous structural templates to design and fabricate NLO materials has promoted their rapid development, compared with the traditional “trial-and-error” methodology. KBe&lt;sub&gt;2&lt;/sub&gt;BO&lt;sub&gt;3&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;, an outstanding usually can be as a good structure prototype for oriented exploring NLO materials. In the crystal structure of KBe&lt;sub&gt;2&lt;/sub&gt;BO&lt;sub&gt;3&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;, the π-conjugated planar triangle anionic group [BO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;3−&lt;/sup&gt; and tetrahedra [BeO&lt;sub&gt;3&lt;/sub&gt;F]&lt;sup&gt;5−&lt;/sup&gt; can be replaced by other π-conjugated planar groups and tetrahedra/polyhedra to form KBe&lt;sub&gt;2&lt;/sub&gt;BO&lt;sub&gt;3&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;-like structures, respectively. After the literature survey, the π-conjugated planar groups are [BO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;3−&lt;/sup&gt; itself or [BO&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;−&lt;/sup&gt;, [B&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;5&lt;/sub&gt;]&lt;sup&gt;4−&lt;/sup&gt;, [B&lt;sub&gt;3&lt;/sub&gt;O&lt;sub&gt;6&lt;/sub&gt;]&lt;sup&gt;3−&lt;/sup&gt;, [CO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;2−&lt;/sup&gt;, [BeO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;4−&lt;/sup&gt;, [BeN&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;7−&lt;/sup&gt;, [BS&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;3−&lt;/sup&gt;, [C(NH&lt;sub&gt;2&lt;/sub&gt;)&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;+&lt;/sup&gt;, while the tetrahedra include [BeO&lt;sub&gt;3&lt;/sub&gt;F]&lt;sup&gt;5−&lt;/sup&gt; itself or [MO&lt;sub&gt;4&lt;/sub&gt;]&lt;sup&gt;&lt;em&gt;n&lt;/em&gt;−&lt;/sup&gt; (M = B, P, S, Si, Li, Be, Al, Ga, Zn, Cl; &lt;em&gt;n&lt;/em&gt; = 1, 2, 3, 4, 5, 6, 7), [SiN&lt;sub&gt;4&lt;/sub&gt;]&lt;sup&gt;8−&lt;/sup&gt;, [BO&lt;sub&gt;3&lt;/sub&gt;T]&lt;sup&gt;4−&lt;/sup&gt; (T = F, (OH)), [MO&lt;sub&gt;2&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;&lt;em&gt;n&lt;/em&gt;−&lt;/sup&gt; (M = P, Si; &lt;em&gt;n&lt;/em&gt; = 1, 2), [MO&lt;sub&gt;3&lt;/sub&gt;F]&lt;sup&gt;&lt;em&gt;n&lt;/em&gt;−&lt;/sup&gt; (M = Li, S, Y; &lt;em&gt;n&lt;/em&gt; = 1, 4, 6), [BeO&lt;sub&gt;3&lt;/sub&gt;(OH)]&lt;sup&gt;5−&lt;/sup&gt;, [AlO&lt;sub&gt;3&lt;/sub&gt;X]&lt;sup&gt;4−&lt;/sup&gt; (X = F, Cl), [ZnO&lt;sub&gt;2&lt;/sub&gt;(OH)&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;4−&lt;/sup&gt;, [ZnO&lt;sub&gt;3&lt;/sub&gt;X]&lt;sup&gt;5−&lt;/sup&gt; (X = (OH), F, Cl, Br), and [ZnS&lt;sub&gt;3&lt;/sub&gt;Br]&lt;sup&gt;5−&lt;/sup&gt;, as well as polyhedra [C&lt;sub&gt;3&lt;/sub&gt;O&lt;sub&gt;4&lt;/sub&gt;H&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;2−&lt;/sup&gt;, [C&lt;sub&gt;3&lt;/sub&gt;H&lt;sub&gt;6&lt;/sub&gt;NO&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;−&lt;/sup&gt;, [AlO&lt;sub&gt;3&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;5−&lt;/sup&gt;, [MgO&lt;sub&gt;4&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;]&lt;sup&gt;8−&lt;/sup&gt;, [A&lt;sup&gt;II&lt;/sup&gt;O&lt;sub&gt;6&lt;/sub&gt;]&lt;sup&gt;10−&lt;/sup&gt; (A&lt;sup&gt;II&lt;/sup&gt; = Mg, Ca), [LaO&lt;sub&gt;8&lt;/sub&gt;]&lt;sup&gt;13−&lt;/sup&gt;, [LaO&lt;sub&gt;9&lt;/sub&gt;]&lt;sup&gt;15−&lt;/sup&gt;, [PbO&lt;sub&gt;3&lt;/sub&gt;X&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;7−&lt;/sup&gt; (X = Cl, Br, I), and [IO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;−&lt;/sup&gt;. Accordingly, about 107 related compounds were collected: 37 borate-halides, 17 fluorooxoborates, 16 borates, 13 γ-Be&lt;sub&gt;2&lt;/sub&gt;BO&lt;sub&gt;3&lt;/sub&gt;F analogues, seven hydroxyborates, four borosulfates, three borophosphates, two guanidiniums, two borosilicates, and one malonate, hydroxycarbonate, carbonate-halide, borate-iodate, sulfate, silicate. According to their relationships between crystal structures and NLO properties: (i) KBe&lt;sub&gt;2&lt;/sub&gt;BO&lt;sub&gt;3&lt;/sub&gt;F&lt;sub&gt;2&lt;/sub&gt;-like materials that can achieve deep-ultraviolet NLO behavior all contain π-conjugated planar groups ([BO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;3−&lt;/sup&gt;, [CO&lt;sub&gt;3&lt;/sub&gt;]&lt;sup&gt;2−","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216632"},"PeriodicalIF":20.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward a molecular-scale picture of water electrolysis: mechanistic insights, fundamental kinetics and electrocatalyst dynamic evolution","authors":"Man Chen,&nbsp;Yingju Yang,&nbsp;Yuandong Ding,&nbsp;Jing Liu","doi":"10.1016/j.ccr.2025.216651","DOIUrl":"10.1016/j.ccr.2025.216651","url":null,"abstract":"<div><div>Scaling up water electrolysis is hindered by the need of low-cost, high-activity, and long-durability electrocatalysts for the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). Although reviews published previously focus exclusively on the electrocatalysts development, there is a lack of review focusing on the microcosmic knowledge of water electrolysis. The rational design of water-splitting electrocatalysts must be grounded in a fundamental molecular-level understanding of both HER and OER. Herein, we provide a comprehensive review of recent advances in molecular-level understanding of water electrolysis and identify the critical challenges throughout the entire process of splitting water to hydrogen, including reaction mechanism, active sites, reaction intermediates, fundamental kinetics, electric double layer, and dynamic evolution of electrocatalysts. Unusual active sites and reaction intermediates detected experimentally are summarized and <em>in situ</em> techniques are highlighted due to their irreplaceable role in unrevealing the dynamic process at the molecular level. We also delve into the kinetic challenges associated with these electrochemical reactions, particularly the sluggish HER kinetics in alkaline media and the identification of rate-determining step of OER. Moreover, the effects of electric double layer and dynamic surface evolution on catalytic performance are discussed to highlight the importance of <em>in situ</em> monitoring the electrolyte/electrode interface. By integrating insights from experimental and theoretical studies, this review aims to offer valuable guidance for the design and development of efficient and durable water-splitting electrocatalysts. The state-of-the-art electrocatalysts and electrolyzers are also summarized to bridge the gap between the research advances and industrial demands. Finally, we provide the outstanding issues and current challenges for obtaining a more complete molecular-level picture of water electrolysis.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216651"},"PeriodicalIF":20.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lanthanide-doped nanoprobes for microRNA detection","authors":"Yunya Liu ,&nbsp;Yin Huang ,&nbsp;Yijun Luo ,&nbsp;Yuxia Luo ,&nbsp;Lijun Jiang ,&nbsp;David Gallego-Ortega ,&nbsp;Yuen Yee Cheng ,&nbsp;Philip A. Gale ,&nbsp;Guochen Bao","doi":"10.1016/j.ccr.2025.216644","DOIUrl":"10.1016/j.ccr.2025.216644","url":null,"abstract":"<div><div>MicroRNAs (miRNAs), a sub-class of non-coding RNAs approximately 20–24 nucleotides in length, have emerged as valuable biomarkers for disease diagnosis and prognosis, and potential forensic evidence. Advances in lanthanide-doped nanoprobes offer great promise for sensitive miRNA detection due to their high photostability, long luminescence lifetimes, and large anti-Stokes shifts. This review provides a comprehensive overview of strategies for developing lanthanide-doped nanoparticle (LnNP)-based biosensors for miRNA detection. We begin by introducing miRNAs as biomarkers in disease diagnostics and discussing synthesis and surface modification approaches for upconversion nanoprobes. We then highlight various detection strategies using lanthanide-doped nanoprobes—including clustered regularly interspaced short palindromic repeats (CRISPR)-based, sandwich structure-based, energy transfer-based, and inductively coupled plasma (ICP)-based detection. Finally, we address current challenges, potential applications and future perspectives for LnNP-based biosensors and their potential for clinical translation.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216644"},"PeriodicalIF":20.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cu-based metal oxide catalysts for NH₃-SCR of NOx: From fundamentals to mechanistic insights","authors":"Sher Ali ,&nbsp;Sharafat Ali ,&nbsp;Ahmed Ismail ,&nbsp;Muhammad Zahid ,&nbsp;Fazal Raziq ,&nbsp;Liang Qiao","doi":"10.1016/j.ccr.2025.216676","DOIUrl":"10.1016/j.ccr.2025.216676","url":null,"abstract":"<div><div>In today's world, emissions from automobile exhaust and industrial chimneys are the major contributors to atmospheric nitrogen oxides (NO_<em>x</em>). NO_<em>x</em> has detrimental effects on both plants and animals and can cause various diseases. Ammonia (NH₃)-based selective catalytic reduction (SCR) is a highly effective method for controlling and mitigating NO_<em>x</em> emissions. Cu-based oxides are extensively utilized in NH₃-SCR processes due to their widespread availability, cost-effectiveness, and outstanding redox capabilities, making them a preferred choice among MO catalysts. The presence of copper in both Cu²⁺ and Cu⁺ oxidation states offers favorable potential for combination with other transition elements, enhancing catalytic performance. In addition, the synthesis methods use in the SCR process, regeneration, and disposal of Cu-oxide-based catalysts are more cost-effective and environment friendly than those of precious metal oxide SCR catalysts, making Cu-based technology a more sustainable and economical choice. While numerous review papers have explored the role of copper in zeolite-based catalysts for NO_<em>x</em> reduction but concise reports focusing on Cu in MO-based catalysts for SCR remain scarce. Therefore, in this work, we aim to review the synthesis methods, reaction mechanisms, structure-activity relationships, economic feasibility, environmental impact assessment and durability of Cu-based oxide catalysts in NH₃-SCR, particularly against water, alkali and alkaline earth metals, SO₂, and other relevant factors.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216676"},"PeriodicalIF":20.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-atom catalysts: Enzyme-mimicking coordinations, platform designs, and biomedical applications","authors":"Xuan Thien Le ,&nbsp;Yu Seok Youn","doi":"10.1016/j.ccr.2025.216642","DOIUrl":"10.1016/j.ccr.2025.216642","url":null,"abstract":"<div><div>Recent advancements in nanotechnology have resulted in the appearance of single-atom catalysts (SACs), along with a novel class of materials with the potential to mimic the performance of natural enzymes for a wide range of biological applications. Characterized by atomically dispersed metal sites anchored on appropriate substrates, SACs render unique electronic configurations and maximized metal atom utilization. These properties enhance catalytic activity, selectivity, and stability, which makes SACs more efficient than normal nanocatalysts. These intriguing features allow SACs to address key challenges in biomedicine, including enzyme-like activity for biosensing, targeted therapy, and disease prevention. SACs have shown significant potential in cancer treatment, oxidative stress reduction, antimicrobial therapies, real-time biosensing, and bioimaging, closing the disparity gap between nanozymes and natural enzymes. Furthermore, SAC platforms are versatile, allowing surface modifications and the integration of other materials to improve biocompatibility, catalytic performance, and multi-functionality. This study reviews progress in SAC synthesis, coordination environments, and platform designs, proving their transformative potential in biomedicine. In addition, the main challenges of SACs for clinical use, such as improving substrate selectivity and biocompatibility or ensuring long-term stability, are also considered. When these limitations are addressed, SACs promise to revolutionize therapeutic strategies and allow new solutions for diagnostic innovations, precision medicine and disease management. This work contributes to the growing understanding of SACs and their future applications in catalytic biomedicine.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216642"},"PeriodicalIF":20.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent progress of advanced Nanozymes for targeted oncotherapy and synergistic immunotherapy","authors":"Wenying Zhang ,&nbsp;Meifang Wang ,&nbsp;Ping’an Ma ,&nbsp;Jun Lin","doi":"10.1016/j.ccr.2025.216674","DOIUrl":"10.1016/j.ccr.2025.216674","url":null,"abstract":"<div><div>Nanozymes are a type of simulated artificial enzymes that possess both the unique properties of nanomaterials and enzyme functions, making them promising alternatives to natural enzymes in the biomedical field. In recent years, with the cross-fusion of nanomedicine and nanocatalysis, significant efforts have been made to regulate the nanozymes further to realize specific antitumor therapy and simultaneously minimize their side effects. In this review, we introduced the latest advances in the intelligent regulation of nanozymes over the past three years, focusing on their activity and specificity. Through machine learning, bionics and chemical design, the catalytic properties of nanozymes can be reasonably predicted and designed, enabling their application in various scenarios. A brief description was also provided on improving their specificity and biosafety through surface modification, multi-stimulation, and tumorous in-situ synthesis. Furthermore, strategies for augmenting antitumor immunity based on nanozymes were well summarized. Finally, main challenges and prospects were proposed for the further biomedical development of nanozymes, including precise manipulation of catalytic route on demand at the molecular level, the relationship between nanozymes and cellular metabolism, the development of more types of nanozyme activities and the challenges faced in clinical translation.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"536 ","pages":"Article 216674"},"PeriodicalIF":20.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}