Coordination Chemistry Reviews最新文献

{"title":"Rare-earth-based materials for exchange membrane water electrolysis: from rational design to device applications","authors":"Yu Zhu,&nbsp;Jinrui Hu,&nbsp;Yu Zhou,&nbsp;Yujie Wang,&nbsp;Mohan Chen,&nbsp;Yawen Tang,&nbsp;Gengtao Fu","doi":"10.1016/j.ccr.2026.217608","DOIUrl":"10.1016/j.ccr.2026.217608","url":null,"abstract":"<div><div>The development of highly efficient electrocatalysts tailored for exchange membrane water electrolysis is pivotal for advancing large-scale green hydrogen production. Rare-earth (RE) elements exhibit unique advantages in modulating electronic structure and enhancing intrinsic electrocatalytic performance, owing to their distinctive 4f electron configuration and strong oxygen affinity. Understanding the precise roles of RE elements and their structure-activity relationships under operating conditions is essential for realizing their application potential. Herein, this review systematically elucidates the theoretical foundations of RE-based materials for boosting catalytic activity and stability from electronic properties. Then, we comprehensively summarize recent advances in RE-modified catalysts for OER and HER reactions and provide an overview of their emerging applications and feasibility in proton exchange membrane water electrolysis (PEMWE) and anion exchange membrane water electrolysis (AEMWE). Finally, we propose rational design strategies and future research directions to address current industrialization challenges. This review aims to provide the important guidance for developing next-generation RE-based electrocatalysts tailored for large-scale water electrolysis.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217608"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146033710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal–organic phosphorescence materials: Optical mechanisms, regulation strategies, and diverse applications","authors":"Lu Wang ,&nbsp;Shuai Chang ,&nbsp;Jian Lv ,&nbsp;Li Ya Liang ,&nbsp;Yan Yin Zhang ,&nbsp;Da Wei Li ,&nbsp;Bin Bin Chen","doi":"10.1016/j.ccr.2026.217607","DOIUrl":"10.1016/j.ccr.2026.217607","url":null,"abstract":"<div><div>Metal–organic phosphorescence materials (MOPMs) are a type of highly efficient room-temperature phosphorescence (RTP) system characterized by the structural integration and photophysical coupling of metal-containing units and organic components. By combining the distinct advantages of both inorganic and pure organic RTP materials, MOPMs exhibit long lifetimes, robust photostability, and low toxicity. These attributes render them highly versatile across various fields. This review provides a comprehensive overview of MOPMs. It begins with their definition and classification, including metal-organic complexes, metal-organic polymers, metal-organic frameworks, metal nanoclusters, metal-doped carbon dots, metal-organic hybrid perovskites, and organic-inorganic metal halides. Subsequently, we systematically elucidate the luminescence mechanisms and the corresponding optical regulation strategies inherent to these systems. Finally, we discuss the applications of MOPMs in photoelectric devices, information storage, bioimaging, therapy, and sensing technologies. This review aims to inspire innovative designs of MOPMs and accelerate their future development for a broader spectrum of applications.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217607"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electron deficient fluorous polycyclic aromatic and heteroaromatic hydrocarbons","authors":"Sebastian Balser,&nbsp;Olga V. Boltalina","doi":"10.1016/j.ccr.2026.217592","DOIUrl":"10.1016/j.ccr.2026.217592","url":null,"abstract":"<div><div>Electron-deficient polycyclic aromatic hydrocarbons (PAHs) and their heteroaromatic analogues have emerged as key building blocks for organic semiconductors, photovoltaics, and optoelectronic devices. Incorporation of perfluoroalkyl (R_F) and perfluoroaryl (Ar_F) substituents into these frameworks significantly enhances electron affinity, lowers LUMO energy levels, and imparts air-, photo- and thermal stability, thereby addressing long-standing limitations of pristine PAHs in <em>n</em>-type materials. This review summarizes recent advances in the synthesis of R_F- and Ar_F-polysubstituted PAHs, highlighting one-step high-temperature gas-phase methods, copper-mediated transformations, and emerging photochemical strategies for selective perfluoroalkylation. Structural insights from single-crystal X-ray diffraction reveal how fluorinated substituents govern molecular conformation, π–π stacking, and solid-state packing, thereby tuning electronic and optical properties. Emphasis is placed on acenes, heteroacenes, phenanthrolines, perylenes, coronenes, and buckybowls, which illustrates the versatility of fluorine-based functionalization in accessing stable, strongly electron-accepting materials with diverse structures and properties.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217592"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146048175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid-state photoswitches based on excited-state intramolecular proton transfer","authors":"Yahui Chen ,&nbsp;Wenjing Wang ,&nbsp;Xin He ,&nbsp;Yaqian Huang ,&nbsp;Huofeng Cen ,&nbsp;Mingle Li ,&nbsp;Hao Gu ,&nbsp;Xiaoqiang Chen ,&nbsp;Juyoung Yoon ,&nbsp;Xiaojun Peng","doi":"10.1016/j.ccr.2026.217589","DOIUrl":"10.1016/j.ccr.2026.217589","url":null,"abstract":"<div><div>Solid-state photoswitches based on excited-state intramolecular proton transfer (ESIPT) have attracted extensive research interest due to their unique photophysical properties and broad potential in functional smart materials. This review provides a comprehensive overview of recent advances in ESIPT-based photoswitches, with a primary focus on imine derivatives, hydrazone derivatives, and other emerging photoresponsive systems. Particular emphasis is placed on their molecular design strategies, mechanistic insights, and solid-state photochromic behaviors, as well as the associated structure-property relationships. The fundamental principles of ESIPT processes are discussed, followed by molecular engineering strategies aimed at enhancing photoisomerization efficiency, controlling excited-state dynamics, and tuning emission characteristics through conformational modulation. Representative applications, including information encryption and optical data storage, ultraviolet sensing, ferroelectric and optoelectronic materials, molecular machines, flexible photonic devices, and crystal actuators, are systematically summarized. Moreover, current challenges such as achieving high switching contrast, improving photofatigue resistance, and enriching optical outputs are critically examined, along with emerging strategies to overcome these limitations. This review aims to provide new insights and perspectives to inspire the rational design of next-generation solid-state ESIPT photoswitches for advanced functional materials.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217589"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145993211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailoring metal–organic frameworks: From morphological control to superstructure assembly","authors":"Zhi-Bo Wang,&nbsp;Hong-Yu Chu,&nbsp;Miao Chang,&nbsp;Chong-Chen Wang","doi":"10.1016/j.ccr.2026.217606","DOIUrl":"10.1016/j.ccr.2026.217606","url":null,"abstract":"<div><div>Over the past three decades, metal–organic frameworks (MOFs) have garnered significant attention owing to their structural diversity and tunable functionalities, demonstrating considerable potential in applications such as environmental remediation and energy storage. However, the performance of MOFs is governed not only by their chemical composition but also, critically, by their morphological characteristics and hierarchical organization. Consequently, achieving precise control over MOFs, from tailored micro-scale morphology to the rational construction of superstructures, has emerged as a pivotal research direction for enhancing their functionality and expanding their applicability. This review comprehensively summarizes recent advances in the precision engineering of MOFs across multiple scales, ranging from single-crystal morphology control to superstructure assembly. We begin by systematically elucidating the roles of key synthesis parameters, external modulators, and template-assisted strategies in directing the size and shape of MOF crystals. Subsequently, we discuss a variety of assembly methodologies, including evaporation-induced, spray-drying, template-assisted, electric-field-induced, depletion-assisted, DNA-directed, liquid-bridging, solvent-assisted, and light-to-heat conversion assembly, that enable the organization of discrete MOF particles into ordered superstructures. Particular emphasis is placed on how the modulation of assembly parameters governs the structural characteristics of the resulting architectures. Finally, we provide a forward-looking perspective on current challenges and future research directions, aiming to inspire further innovation in the precise design and controlled assembly of next-generation MOF materials.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217606"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146033709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cooperative, anti-cooperative, and synergistic supramolecular interactions mediate self-organization of self-assembling dendrons, dendrimers, and dendronized macromolecules","authors":"Virgil Percec ,&nbsp;Dipankar Sahoo ,&nbsp;Devendra S. Maurya ,&nbsp;Jasper Adamson","doi":"10.1016/j.ccr.2026.217588","DOIUrl":"10.1016/j.ccr.2026.217588","url":null,"abstract":"<div><div>After a brief discussion of the discovery of covalent and self-organizable dendrons, dendrimers, and dendronized macromolecules, examples of cooperative, anti-cooperative and synergistic supramolecular-interactions mediating self-assembly and self-organization of supramolecular dendrimers will be presented. Dendronized crown-ethers will be used to demonstrate these interactions generated by cation-dipole, π–π stacking, H-bonding, fluorination, the specialty of Professor Giuseppe Resnati celebrated with this occasion, and covalent macromolecular interactions. It will be demonstrated that fluorination of self-assembling dendrons generates a simple approach to dendronized donors and acceptors and of their donor-acceptor complexes. The evolution of helical chirality from its discovery in tobacco mosaic virus-like supramolecular dendrimers to helical-globular-dendrimers producing chiral Frank-Kasper and quasicrystal periodic and quasiperiodic arrays will be highlighted. Helical Aquaporin-like transmembrane proteins and spherical containers will be assembled from dendritic dipeptides by a combination of H-bonding and aromatic π–π interactions. The work of Giulio Natta will be honored by a discussion of the dendronized helical stereoisomers of poly(phenylacetylene) and their intramolecular electrocyclization. Polymer chemistry will be employed as a tool to support the quasi-equivalence of self-assembling dendrons and elaborate their shape inversion from helical spheres to helical columns. Helical supramolecular dendrimers induce a helical conformation into atactic-polymer backbones, a dream which even Giulio Natta could not think of. Hydrophobic, H-bonding and ion-ion interactions generated self-assembling amphiphilic Janus dendrimers and glycodendrimers which mimic cell membranes, their glycans, and provide one-component multifunctional sequence-defined ionizable amphiphilic Janus dendrimers which target the delivery of mRNA to specific organs for stable vaccines and therapeutics.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217588"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145976068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Point-of-Care Diagnostics with Biomolecule-Functionalized Upconverting Nanomaterials","authors":"Jitender Kumar ,&nbsp;Renrui Sun ,&nbsp;Wen Gao ,&nbsp;Lining Sun","doi":"10.1016/j.ccr.2026.217611","DOIUrl":"10.1016/j.ccr.2026.217611","url":null,"abstract":"<div><div>The advent of point-of-care (POC) diagnostics using nanomaterials is an emerging trend in modern healthcare, enabling rapid, on-site detection of diseases with high sensitivity and specificity, and reducing dependence on centralized laboratories. Lanthanide-doped upconverting nanoparticles (UCNPs), owing to their unique near-infrared-excited luminescence, exceptional photostability, minimal autofluorescence, and deep tissue penetration, have garnered significant attention as advanced optical nanoprobes for bioanalytical applications. However, leveraging their full potential in POC diagnostics requires precise surface functionalization with biomolecules such as nucleic acids, proteins, aptamers, and small-molecule ligands to enhance biorecognition, stability, and signal transduction efficiency. This review provides a comprehensive analysis of recent advancements in biomolecule-functionalized UCNPs for POC applications. It highlights their integration into cutting-edge biosensing platforms, including Förster resonance energy transfer-based immunoassays, clustered regularly interspaced short palindromic repeats (CRISPR)-associated UCNP biosensors for nucleic acid amplification-free detection, and UCNP-enabled Lateral Flow Assays for rapid screening. Additionally, progress in microfluidic and smartphone-integrated UCNP diagnostics is discussed, emphasizing their potential for real-time and multiplexed detection. Finally, challenges such as sensitivity, stability, and scalability are addressed, with future directions proposed for advancing UCNP-based POC diagnostics. This review underscores the transformative role of functionalized UCNPs in POC biosensing and their clinical translation potential.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217611"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146014670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular recognition-mediated dynamic networks in hydrogel biomaterials","authors":"Xiangyu Wu ,&nbsp;Zhaoyang Yao ,&nbsp;Jia Gao,&nbsp;Guoqing Pan","doi":"10.1016/j.ccr.2026.217625","DOIUrl":"10.1016/j.ccr.2026.217625","url":null,"abstract":"<div><div>Hydrogels have found extensive applications in the biomedical field, due to their outstanding biocompatibility and tunable physicochemical properties. However, conventional hydrogels often suffer from limited adaptability and inadequate dynamic responsiveness, which significantly hampers their performance in complex physiological environments. Compared with the non-specificity and high reactivity of reversible covalent interactions, molecular recognition relies on specific and spatially complementary noncovalent bonds, thus providing a reversible but powerful and versatile approach to constructing dynamic hydrogel networks. Dynamic hydrogels mediated by molecular recognition exhibit tunable mechanical strength, efficient self-healing capabilities, and precise stimulus-responsive behaviors, thereby expanding their potential in diverse biomedical applications. This review summarizes recent advances in molecular recognition-mediated dynamic hydrogels, covering systems based on purely chemical recognition as well as those derived from natural biological recognition elements. We further discuss their applications in tissue engineering, drug delivery, and biosensors, with particular emphasis on how molecular recognition regulates hydrogel dynamics and modulates cellular responses and tissue healing. The development of molecular recognition-mediated dynamic hydrogels will establish a systematic theoretical foundation and offer a versatile strategy for the next generation of dynamic biomaterials.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217625"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146036294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vivo NIR-II fluorescence imaging based on microscopy set-ups: probes, set-ups, bioimaging and bioanalysis applications","authors":"Yanling Yang ,&nbsp;Hongxin Zhang ,&nbsp;Zhen Yang ,&nbsp;Wei Huang","doi":"10.1016/j.ccr.2026.217598","DOIUrl":"10.1016/j.ccr.2026.217598","url":null,"abstract":"<div><div>The emerging second near-infrared (NIR-II, 1000–2300 nm) fluorescence imaging based on microscopy set-ups (NIR-II FLI MS) has been proven to enable real-time tracking of dynamic physiological processes and facilitate the reconstruction of clear two- and three-dimensional morphological images of living tissues, which can offer high signal-to-background ratio and imaging contrast of live tissues at the cellular level. Focusing on the significant role of NIR-II FLI MS in intravital imaging and bioanalysis, in this contribution, we begin with the performance trade-off between NIE-II fluorescence probes and microscopy set-ups, focused on specific requirements for fluorescent probes across different NIR-II FLI MS modalities and feasible strategies to enhance their optical performances of the different NIR-II probes. Subsequently, we summarize recent advances in NIR-II microscopy set-ups, with an emphasis on the operational principles and specific requirements of wide-field, confocal, and light-sheet systems for high-performance in vivo detection. The cutting-edged applications of these probes and set-ups for in vivo NIR-II FLI MS is also discussed in detail. Finally, we provide a comprehensive and interdisciplinary analysis of the enduring challenges and prospective directions within this field, aiming to inspire further development of novel NIR-II high-performance probes and microscopy technologies for advanced intravital detection and facilitate the transition of in vivo NIR-II FLI MS from “technology-driven” to “science-driven”.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217598"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carrier-free drugs as smart nanomaterials for cancer theranostics","authors":"Namratha Parthasarathy ,&nbsp;Jeongah Shin ,&nbsp;Ramar Thangam ,&nbsp;Parameswaran Chidambara Rajan ,&nbsp;Babu Rithisa ,&nbsp;Selvaraj Shyamsivappan ,&nbsp;Mary Fabiola ,&nbsp;Heemin Kang ,&nbsp;Raju Vivek","doi":"10.1016/j.ccr.2026.217601","DOIUrl":"10.1016/j.ccr.2026.217601","url":null,"abstract":"<div><div>Nanocarriers have gained widespread applications in cancer theranostics by incorporating the fundamental concepts of nanotechnology. Drug delivery systems (DDS) based out of nanocarriers have outstanding prospects for biomedical applications due to their remarkable blood distribution, superior retention of drugs in tumors, and enhanced potential for combination therapy. However, two significant barriers have impeded the advancement of nanocarriers: the possibility of nanocarrier toxicity and poor loading of drugs into the nano DDS. Carrier-free drugs (CFDs) delivery nanosystems are an inventive alternative to these challenges and have drawn much interest in cancer therapy and stand out as an achievable solution to these obstacles. CFDs are developed on a nanoscale, without any requirement of additional excipients, and consequently have excellent pharmacokinetics and intracellular delivery. The key highlights of this review include preparation techniques, pharmacokinetics, covalent, non-covalent interactions and optimization of CFDs. The potential of CFDs in cancer theranostics is explored under specific interactions based on drugs, such as drug-drug, drug-photosensitizer, drug-metal, drug-antibody, and drug-peptide interactions. To the best of our knowledge, this review is the first to discuss the design of carrier-free drugs for cancer theranostics, with a prime focus on drug-based interactions that serve as the major basis for their self-assembly. Thus, by addressing the multifaceted aspects of CFDs, the review attempts to present a comprehensive perspective of CFDs and provide novel insights for more effective cancer therapeutics.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"554 ","pages":"Article 217601"},"PeriodicalIF":23.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146014668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}