{"title":"Mitigating of Paracetamol-induced Hepatotoxicity in Albino Mice Using Boerhaavia diffusa Extracts","authors":"Praveen Goswami, Shilpi Damor, Utkarsh Kaushik","doi":"10.56557/upjoz/2024/v45i154225","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154225","url":null,"abstract":"Boerhaavia diffusa, renowned for its therapeutic efficacy in chronic liver diseases, operates through multifaceted mechanisms to uphold internal homeostasis. Its pivotal roles encompass modulation of intermediary metabolism of macromolecules, synthesis of crucial plasma proteins, enzymatic activities, and bile excretion.In this investigation, we aimed to evaluate the hepatoprotective potential of Boerhaavia diffusa against paracetamol-induced hepatotoxicity in rats. Our study revealed promising outcomes as the extracts obtained from Boerhaavia diffusa demonstrated a significant hepatoprotective role in albino rats subjected to hepatotoxicity induced by paracetamol administration. During the study, the animals were administered doses of 1g/kg b.wt and 2 g/kg b.wt of the plant extracts. Following paracetamol administration, conspicuous changes were observed in hepatocyte biochemical markers, indicative of hepatotoxicity. However, treatment with Boerhaavia diffusa extracts ameliorated these alterations, underscoring their potential to mitigate paracetamol-induced liver injury. These findings underscore the significant hepatoprotective properties inherent in the plant extracts derived from Boerhaavia diffusa. which can be utilized as a potential therapeutic avenue for the management of paracetamol-induced liver damage. These findings hold promise for the development of novel therapeutic interventions aimed at safeguarding liver health and mitigating the adverse effects of hepatotoxic insults.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141672628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Length-weight Relationship and Relative Condition Factor of Paratrypauchen microcephalus (Bleeker, 1860) along the Mumbai Coast","authors":"Ruchi Pujari, B.M. Gore, S.P. Jumale","doi":"10.56557/upjoz/2024/v45i154222","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154222","url":null,"abstract":"The length-weight relationship and relative condition factor of Paratrypauchen microcephalus (Bleeker, 1860) from Madh, Mumbai, was studied between October 2021 and December 2022. A total of 179 fish were examined, which included 81 males, 75 females, and 23 juveniles. The relationship between total length and weight was estimated by the least squares method, and the results indicated that the species exhibits a negative allometric growth pattern, with the exponent ‘b’ values obtained being 1.1545 for males, 1.1728 for females, 1.0260 for juveniles, and 0.9443 for the pooled observations. The regression values obtained were highly significant (P < .01), showing a good relationship between the length and weight of this fish. The mean value for the relative condition factor (Kn) obtained during the study was 0.5757, 0.6610, and 2.4730 for males, females, and juveniles, respectively, reflecting that males and females are not in a better health condition while juveniles are, having a Kn value greater than 1. The current study thus provides the first baseline data about LWRs and the relative condition factor of this fish species from the Mumbai coast.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Importance of Birds from Non-Tidal Wetlands: A Review","authors":"M. J. Lubal","doi":"10.56557/upjoz/2024/v45i154217","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154217","url":null,"abstract":"Wetlands are the lands transitional between terrestrial and aquatic eco-systems where the water is usually at or near the surface or the land is covered by shallow water. They are most productive, valuable, and provide a wide range of goods and services. Wetland birds rely on waterways for survival and each bird species has its own requirements for food, shelter and breeding sites. Monitoring of wetland birds is an engaging activity that provides researchers with an insight into the functioning and health of wetlands. Despite the high value of services derived from wetlands, they have been systematically drained and filled to support agriculture, urban expansion, and other developments. Agriculture, climate change, draining, dredging, introduced species, pollution, salinization, and urbanization are the major threats to wetlands. In light of these observations, the aim of this review is to update recent information from the available literature relating with the ecosystem services provided by birds from non-tidal wetlands.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141673544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nithya K., A. M. Imthiyas, S. Jagadeeswari, P. Vidya
{"title":"Green Synthesis and Comprehensive Characterization of Silver Nanoparticles Using Lawsonia inermis Extract for Biological Applications","authors":"Nithya K., A. M. Imthiyas, S. Jagadeeswari, P. Vidya","doi":"10.56557/upjoz/2024/v45i154223","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154223","url":null,"abstract":"This research focuses on the production, characterization, and application of silver nanoparticles (AgNPs) for biomedical research. An eco-friendly extracellular biosynthetic method was employed, utilizing aqueous leaf extracts of Lawsonia inermis (Henna) as reducing agents. The synthesized AgNPs were characterized using UV-Vis spectroscopy, showing an absorption peak at 424 nm. FT-IR analysis was conducted to identify chemical groups present in nanoparticles. TEM and SEM analyses revealed that AgNPs were spherical and ranged in size from 10 to 50 nm. Staphylococcus aureus, Klebsiella, Salmonella, and Escherichia coli were inhibited by the green-synthesised AgNPs. Penicillium, Aspergillus niger, Aspergillus flavus, and Fusarium showed antifungal activity, forming zones of inhibition. Furthermore, the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values were found to be 75 mg/ml (Escherichia coli ATCC25922) and the MIC value was 50 mg/ml for the same strain. These nanoparticles demonstrated significant anti-inflammatory activity and dose-dependent cytotoxicity against A549 lung cancer cells. As a result of the synthesized nanoparticles, strong antioxidant activity was observed. The results suggest that plants can be effectively used as a resource for the production of silver nanoparticles. Such particles have potential applications in numerous fields such as biomedical research and nanotechnology.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141676369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashwit S. Shetty, Rushikesh V. Devre, Hitesh U. Shingadia
{"title":"Checklist of Intertidal Organisms of Dana Pani Beach, Mumbai Suburban, Maharashtra, India","authors":"Ashwit S. Shetty, Rushikesh V. Devre, Hitesh U. Shingadia","doi":"10.56557/upjoz/2024/v45i154219","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154219","url":null,"abstract":"Dana Pani Beach is located in Malad West, Mumbai Suburban, Maharashtra at 19°10'10.88\"N Latitude and 72°47'18.20\"E Longitude. There is very scanty research data available on this beach location. The study was conducted from March 2022 to June 2023. The beach is a tourist place and fishery activities are also carried out which had a heavy impact on the site due to constant anthropogenic interruption. This is a tentative checklist of intertidal flora and fauna to investigate the diversity vis-à-vis environmental and/or anthropogenic devastation caused to the habitat. The species identification was carried out by referencing through respective field guides The specimens were carried out using DSLR and smartphone camera. and different online repositories based on marine faunal and flora. The Intertidal species with the ability to withstand such vagaries (littering the place with broken glasses of alcohol bottles, immersion of idols, and littering plastic bags) were found in abundance. Two marine algal populations in abundance were observed to be Ulva and Gracillaria. The mangrove community was dominated by Avicennia marina and Sonneratia apetala. Anthozoans and Polychaetes showed the lowest diversity when compared with other groups of organisms. The bird population was most abundant within the habitat. In order of abundance, the animal population was represented by 20% Aves = 17% Malacostraca = 17% Gastropods > 9% Teleostei > 5% Bivalvia > 4% Hydrozoa > 2% Anthozoans = 2% Hexanauplia = 2% Polychaetes > 1% Cephalopoda > 1% Hexapoda From the study, it can be concluded that the rocky shore is quite diverse in terms of gastropods, crabs, and green algae in comparison to the sandy shore and mudflat. In totality, 82 faunal and floral species were observed at the site. This checklist is the promising baseline for future studies on this site for the biodiversity of specific animal groups or intertidal ecology.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141675618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Study on Impact Assessment of Dead Fish on the Quality Parameters of Fresh and Sea Water","authors":"Trisha Waghela, Vandita Bhatt, Ammar Dariwala, Dineshkumar Saroj","doi":"10.56557/upjoz/2024/v45i154218","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154218","url":null,"abstract":"Water is vital for ecosystems, supporting biodiversity and sustaining life. Changes in water quality can affect the ecosystem’s animal inhabitants. Decomposition of fish carcasses can lead to deterioration in water quality, posing risk to aquatic animals. This investigation was aimed evaluate the impact of fish carcass on freshwater and seawater quality, by analysing physical and chemical parameters, temperature, salinity, density, pH, Total Dissolved Solids (TDS) and Dissolved Oxygen (DO). Water quality is characterised by physical, chemical, and biological attributes and could be assessed by analysing several parameters such as pH, Temperature, Salinity, DO, and TDS. It was observed that the temperature of freshwater to be 29°C and sea water to be 27°C. There was a decline in density, Dissolved Oxygen, Total Dissolved Solids and pH in both seawater and freshwater, after introducing fish carcass, over the period of three weeks. This study summarizes natural calamities, anthropogenic activities and varied pollution in aquatic environments leading to death of large numbers of aquatic animals which may cause deterioration of water quality and depletion of aquatic biota.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141673920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Noise Pollution Level in the Metro Construction Site in Mumbai, India","authors":"Joel Massey, Swati Bande","doi":"10.56557/upjoz/2024/v45i154221","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154221","url":null,"abstract":"Biological communities in natural systems may show more complex responses to noise than expected from direct effects on acoustically oriented taxa through indirect effects that cascade through communities. There is no doubt that the construction of large infrastructure such as railroads, highways, airports, bridges and subways contribute magnificently towards the social-economic opportunities for the development of a region. But the infrastructures though contributing greatly towards development/civilization their construction is also responsible for the deterioration of the natural environment in the greater areas where these projects are located. In this study, we used a simple decibel meter (HT-80A) and other basic assessment techniques to study the environmental impact of the construction work. Noise can directly affect organisms via several mechanisms, such as acoustic masking, distraction and aversive effects, noise should have stronger direct impacts on animals with, as opposed to without, auditory receptors. The radius for the assessment of the negative impacts of construction work on the environment is set based on the observation of the high noise level of construction work reaching a certain distance in comparison to the standard noise level of traffic (75dB(A) – 85dB(A)).The main reason for this study is the daily observation of the use of high-tech & big machinery on the site of metro construction which was emitting high levels of noise & air pollution exceeding the standard noise level set by The Government of India (45dB(A)-65dB(A)) [1]. The findings of this noise level pollution evaluation revealed negative impact such as anxiety, depression, headache, stress etc. due to the construction work of the metro. The environment is deteriorating which is harmful to the social-economic and richness of the ecosystem as well as to the organism living in the locality. This study contributes to society’s richness and maintenance by creating awareness and giving a near to accurate value on the harmful impact of construction work. The project contractors like Stakeholders, Policy Makers and Urban Planners can use this study for refinement of their project in a way such as to use sound-proof barrier around the machines like SANY SR285R which produces noise levels as high as 115 dB(A). This study can also be used to do carry out proper maintenance of the machines depending on the noise level generated.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Larvicidal Effects of Plant Extract and Bacillus thuringiensis.var israelensis on Aedes aegypti (Diptera: Culicidae)","authors":"Sony X. Vincent, E. G. Marin","doi":"10.56557/upjoz/2024/v45i154220","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154220","url":null,"abstract":"Mosquitoes are the most important group of arthropods that transmits disease causing pathogens. Several plants are used in traditional medicines for the mosquito larvicidal activities in many parts of the world. The use of bacterial toxin in plant extract has a remarkable effect on the larvae of the mosquito. The larvicidal efficacy of plant extract Annona squamosa with B. thuringiensis was tested against third-instar larvae of Aedes aegypti. The mean mortality and percentage mortality of larval populations were noted at different concentrations after 24 and 48 hours period of exposure. Bti and extracts of Annona squamosa showed high insecticidal activity with LC 50 and LC 90. The values of LC 50 at 24 and 48hours exposure are 17.34 and 15.70 respectively. Values of LC 90 at 24 and 48 hours exposure are 31.48 and 28.38 respectively.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141676072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Evaluation of Use Decellularized Cartilage as a Bio Scaffold for the Repair of Articular Cartilage in Dogs with Osteoarthritis","authors":"A. W. Sadeq, B. Khashjoori","doi":"10.56557/upjoz/2024/v45i154216","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i154216","url":null,"abstract":"Articular cartilage lacks the ability to repair itself because it is devoid of blood vessels, nerves, and lymph, and there is no effective treatment that contributes to the cartilage repair process. Osteoarthritis (OA) represents a difficult challenge and an increasing health care burden worldwide. Nowadays, the generation of scaffolds has received great and increasing attention in order to preserve the biophysical environment and bioactive factors. In addition, improved decellularization technology has contributed to providing new promising solutions in the treatment of OA. \u0000Osteoarthritis (OA): Osteoarthritis (OA)is a common and debilitating joint disease that effects of dogs worldwide. Treating cartilage abnormalities is challenging due to the restricted regenerative capacity of cartilage and the constraints of existing therapies. Therefore, there is a need for novel and innovative therapies that can target the underlying causes of osteoarthritis and promote cartilage regeneration. This study was conducted to evaluate the efficacy of decellularized cartilage for treating full-thickness defects of articular cartilage in dogs. \u0000Methodology: Methodology ten dogs, healthy adult cross-breed, they were divided into two equal groups, Group I (the control group) was left without treatment. While group II (the DC group) was treated by the application of decellularized cartilage, in this research, we investigated the utilization of decellularized xenograft articular cartilage is treatment can, the dogs were euthanized on day 56 after surgery. Clinical, macroscopic evaluations were performed. \u0000Results: Results statically analysis of pain, lameness at walking and trot showed effectively reduce pain and improve functionality in severe stifle osteoarthritis. Macroscopically, the fibrous tissue appeared to fill the gap with the complete absence of the bone marrow of the decellularized cartilage group compare with control group. \u0000Conclusion: Conclusion decellularized cartilage used as a treatment can effectively reduce pain, enhance movement and accelerate cartilage regeneration.","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sujal Chaudhari, Arya Upadhya, Dinesh Kumar Saroj, Hitesh U. Shingadia
{"title":"Biometric Characteristic Study of Green Lipped Mussel, Perna viridis (Linnaeus, 1758) From Malad Creek, Mumbai, India","authors":"Sujal Chaudhari, Arya Upadhya, Dinesh Kumar Saroj, Hitesh U. Shingadia","doi":"10.56557/upjoz/2024/v45i144212","DOIUrl":"https://doi.org/10.56557/upjoz/2024/v45i144212","url":null,"abstract":"Biometric Studies are essential to understand the growth rate of the species which helps understand the growth patterns, reproduction rate and population distribution of the species. Growth patterns of molluscs help in evaluating their production potential and energy flows through populations and their distribution. Perna viridis (Linnaeus, 1758) commonly known as the green-lipped mussel or the Asian green mussel belongs to the family Mytilidae. It is distributed along the Indo-Pacific region. They are attached to the rocky substratum along the coast, in the intertidal region. The Biometric Analysis and Length-Weight Relationship study was carried out on Perna viridis (Linnaeus, 1758) to understand their growth rate and population distribution through the Coast of Mumbai. A total of 100 samples were used in this study. The correlation between the Total Weight of the Shell with the organism (WSO) to the Shell Length (SL), Shell Width (SW) and Shell Height (SH) and the correlation between the Soft Tissue Weight of the Organism (WO) to the Shell Length (SL), Shell Width (SW) and Shell Height (SH) gave an idea about the growth factors. The Relative Condition Factor was determined by equation W = aLb. The b values of each correlation showed negative allometric growth with p value to be p<.001 with same significance in Pearson Correlation test. The Relative Condition Factor of WSO-SW and WSO-SL was observed to be above 1 indicating good growth conditions. Thus, biometric studies are a useful tool in study of Perna viridis (Linnaeus 1758) biology, physiology, ecology, growth potential, stock assessment, genetics and breeding of Perna viridis (Linnaeus, 1758).","PeriodicalId":278386,"journal":{"name":"UTTAR PRADESH JOURNAL OF ZOOLOGY","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}