{"title":"Displacement and its derivatives measurement from a single fringe pattern in coherent optical techniques","authors":"C. Quan, Deepan Balakrishnan, C. Tay","doi":"10.1109/3M-NANO.2016.7824932","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824932","url":null,"abstract":"In this paper, displacement and displacement derivatives measurement methods are proposed for digital holographic and speckle pattern interferometry. A complex-phasor method is proposed to determine high quality wrapped phase maps in digital holographic interferometry. A Teager operator based phase derivative determination method is developed to determine unwrapped slope maps from a reconstructed complex field obtained from complex phasors method. Since this method is not suitable for direct slope measurements from a single fringe pattern, a novel method to determine phase derivatives from fringe density and fringe orientation map is developed. In addition, a novel regularized phase tracker model for phase demodulation from a single fringe pattern is proposed. This model utilizes predetermined phase derivatives values so it requires less computation time. The proposed methods are validated with corresponding experiments and results show that they are accurate and robust against speckle noise. The proposed methods have common advantages that they require only one frame at every deformed state and do not require any phase shifting. Hence the methods are suitable for real time dynamic measurements.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131310885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dynamic analysis of the micro-milling system based on ANSYS workbench","authors":"Jinkai Xu, Zeng Ren, Huanhuan Ren, Huadong Yu, Zhanjiang Yu","doi":"10.1109/3M-NANO.2016.7824934","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824934","url":null,"abstract":"The dynamic characteristic of the machine tool has a very important influence on the quality of the workpiece. In particular, the high speed micro milling process puts forward higher requirements for dynamic characteristics. We take the micro-milling system as the research object and use ANSYS Workbench to establish the 3D solid model of the micro-cutting system, then simplify it. Using workbench ANSYS to carry on the static analysis, the modal analysis and Harmonic response to the micro-milling system, the weak link of the micro-milling system is pointed out, which provides guidance for the further optimization.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127672345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kai Guof, Ru Zhangf, Xuming Sun, D. Gurav, Kun Qian
{"title":"Novel surface engineered micro-needles towards bio-analytical applications","authors":"Kai Guof, Ru Zhangf, Xuming Sun, D. Gurav, Kun Qian","doi":"10.1109/3M-NANO.2016.7824914","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824914","url":null,"abstract":"Surface engineering is crucial to enable the functions of materials and device in diverse research fields. Although micro-needles have unique advantages for bio-analytical application, its surface engineering is rarely investigated. Herein, we present several physical/chemical approaches to engineer the surface of micro-needles which may serve as a novel platform for bio-analytical applications.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132944064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Hirvonen, Yuli Lai, P. Kallio, Gisela Cunha, Orlando Rojas
{"title":"Automated estimation of contact angle on hydrophobic fibers using a microrobotic platform","authors":"J. Hirvonen, Yuli Lai, P. Kallio, Gisela Cunha, Orlando Rojas","doi":"10.1109/3M-NANO.2016.7824935","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824935","url":null,"abstract":"This paper presents an automated computer vision algorithm for estimating contact angles that a droplet of probe liquid forms on hydrophobic fibers. A specially designed microrobotic platform is utilized in manipulating the microscopic fibers, shooting droplets in the scale of tens of nanoliters on the fibers and capturing images of the experiments. The images are then processed with the automated computer vision algorithm. The algorithm is proven to be reliable and repeatable with totally 29 experiments on five different bio-based fiber samples.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128340787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Zhao, Zhengxun Song, Si-Yuan Zhang, Zuobin Wang
{"title":"Simulation analysis of coupling characteristics between cardiac myocyte and MEAs","authors":"Li Zhao, Zhengxun Song, Si-Yuan Zhang, Zuobin Wang","doi":"10.1109/3M-NANO.2016.7824989","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824989","url":null,"abstract":"The electrophysiological properties of excitable cells can reflect the state of cells. However, the action potentials (APs) are weak and difficult to detect. The influencing factors of AP measurement are studied by analyzing the equivalent circuit model between cardiac myocyte and microelectrode. After simulation experiments, the improved methods of the parameters that greatly influence on the signal measurement were adopted, and the dialectical relationship among the parameters was analyzed. Aiming at the problem of low signal resolution in planar microelectrodes array, the adjusted methods of electrode parameters were proposed. The experimental results show that the proposed method can change some parameter serious influencing on signal measurement, and is useful to obtain the state between APs and cell more accurately.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125850538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Hou, Zuobin Wang, Yujing Zhao, Yingmin Qu, Xinyue Wang
{"title":"A method for the mechanical stimulation of living single-cells using a voltage-excited AFM probe","authors":"F. Hou, Zuobin Wang, Yujing Zhao, Yingmin Qu, Xinyue Wang","doi":"10.1109/3M-NANO.2016.7824984","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824984","url":null,"abstract":"In this paper, we developed a method to drive the oscillation of AFM conductive probe cantilever for stimulating living single cells in liquid with an AC-voltage excitation. We took a copper foil stuck at the bottom of the petri dish as an electrode and the AFM conductive probe was used as both a nano electrode and an actuator to stimulate the living cells when a bias voltage was applied to the electrodes. The voltage and distance between the two electrodes can be adjusted to obtain various required stimulation effects. In the work, the application of electrostatic force and electrolysis for stimulating living cells with bias voltages was analyzed. The experiment results have shown that the method is able to perform controllable stimulation and precise positioning of cells with the AFM The developed system is an efficient stimulation tool for the study of cellular physiological behaviors.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120972029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lanjiao Liu, Zuobin Wang, Z. Weng, Li Li, Jixing Cai, Litong Dong, Zhengxun Song, Hongmei Xu
{"title":"Nanomanipulation of single nanowires on structured surfaces fabricated by laser interference lithography","authors":"Lanjiao Liu, Zuobin Wang, Z. Weng, Li Li, Jixing Cai, Litong Dong, Zhengxun Song, Hongmei Xu","doi":"10.1109/3M-NANO.2016.7824985","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824985","url":null,"abstract":"Nanomanipulation is an important technology to fabricate and assemble nanostructures, especially for the asymmetrical structures. This paper presents a method of manipulation of single nanowires on structured surfaces by nano grippers in a scanning electron microscope (SEM). In the method, the structured surfaces of substrate were fabricated by two-beam laser interference lithography. Single nanowires were manipulated on the structured surfaces by nano grippers in the SEM. The method uses a pattern to solve the problem that a single nanowire is too tiny to be picked up and manipulated with nano grippers.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121545341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Measurement of viscoelastic properties of living SMCC-7721 cells by atomic force microscopy","authors":"Xinyao Zhu, Xianping Liu, Zuobin Wang","doi":"10.1109/3M-NANO.2016.7824959","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824959","url":null,"abstract":"Elastic properties of carcinoma cells are frequently measured from which malignant cells could be distinguished from their benign counterparts. However, the viscoelastic properties of cancerous cells do not receive their deserved attention since biological cells are more or less viscous. In this regard, the goal of this study is to explore, verify and quantify the viscoelastic properties of human liver cancerous cells (SMCC-7721 cells). To accomplish this objective, creep tests are performed on single 7721 cells by using the constant force delay mode of atomic force microscopy (AFM), and the resulted indentation depth-time curve is fitted by a theoretical model which takes profile of AFM probe and viscoelastic constitution of 7721 cells into consideration. The result indicates that this theoretical model provides good fitting coincidence and the order of magnitude of the extracted parameters also coincides with that of previous studies.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132971519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tip modeling of a probe for nanochannel fabrication","authors":"Zhiyong Guo, Yanling Tian, Chongkai Zhou, Dawei Zhang","doi":"10.1109/3M-NANO.2016.7824937","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824937","url":null,"abstract":"The Berkovich probe used for nanochannel fabrication is modeled as a spherically tipped regular triangular pyramid in this paper. The sphere tip model and triangular pyramid tip model dominate in the small and large scratching depth, respectively. Based on the developed model, the horizontal projected areas of the tip-sample interfaces in both single and multi scratching are analyzed, which can be used for the normal force calculation, and further guide the scratching depth prediction. According to the analysis, the tip-sample interface of the sphere tip model is independent of the scratching direction, while in the triangular pyramid tip model scratching, the tipsample interface is related to the scratching direction in single scratching, and the scratching direction, scratching depth in multi scratching.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131980073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feeling paramagnetic micro-particles trapped inside gas bubbles: A tele-manipulation study","authors":"I. Khalil, Youssef Michel, Baiquan Su, S. Misra","doi":"10.1109/3M-NANO.2016.7824920","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824920","url":null,"abstract":"Surface tension forces, pressure forces, and drag forces arise once a micro-particle comes into contact with a gas bubble or a biological cell in diverse physical and biomedical applications such as targeted therapy, sorting, and characterization of cancer cells. We experimentally demonstrate that these forces can be estimated, scaled-up to the sensory range of a human operator, and sensed during a transparent bilateral tele-manipulation using an electromagnetic system and a haptic device. We find good agreement between the estimated interaction forces and the measured forces using a calibrated microforce sensing probe. The maximum interaction force between a trapped paramagnetic micro-particle and an oxygen bubble is estimated to be 4 ßN. The estimated interaction force is scaled-up and used in the design of a tele-manipulation system (haptic device and an electromagnetic system) that enables motion control of the bubble in a two-dimensional space, while sensing the interaction forces with the bubble. We demonstrate experimentally that the operator senses maximum interaction force (surface tension, pressure, and drag forces) with the same order of magnitude as the calculated theoretical forces. The estimation of interaction forces at this scale provides broad possibilities in targeted therapy and characterization of cancer cells.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124643312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}