Mingjie Tang, Mingkun Zhang, Shihan Yan, Liang-ping Xia, Zhongbo Yang, Dongshan Wei, H. Cui, Chun-lei Du
{"title":"Detection of oligonucleotides based on terahertz spectroscopy and microstructure","authors":"Mingjie Tang, Mingkun Zhang, Shihan Yan, Liang-ping Xia, Zhongbo Yang, Dongshan Wei, H. Cui, Chun-lei Du","doi":"10.1109/3M-NANO.2016.7824991","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824991","url":null,"abstract":"DNA mutations are analyzed by terahertz (THz) spectroscopy in a label-free manner. The 5 base mutations from the 3'-terminus on single stranded 17nt oligonucleotides have first been detected based on the microchannel. The mutations have also been validated based on the split-ring resonators (SRRs). The results clearly demonstrate the ability of THz spectroscopy combined with microstructure for label-free detection of base mutations of DNA biomolecules. This study has proved that the THz spectroscopy can be considered as a prospective diagnostic tool for studying the interaction of molecules such as DNA mutations.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116752597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on surface quality in micro milling stainless steel 06Cr17Ni12Mo2 processing","authors":"Huadong Yu, H. Yuan, Jinkai Xu, Wanwu Hou, Yun Qi","doi":"10.1109/3M-NANO.2016.7824933","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824933","url":null,"abstract":"In this paper, the solid carbide end milling cutter was used to carry out single factor and multi factors orthogonal experiment of micro milling stainless steel 06Cr17Ni12Mo2, and the surface roughness Ra was detected. Also, SEM (Scanning Electron Microscope) was used to observe the surface burrs and the groove bottom morphology. The influence of cutting parameters (spindle speed, feed speed, axial cutting depth) on the groove bottom surface roughness were analyzed.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130637617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rose petal mimic surface by TiO2 sol-gel process","authors":"Zhuhui Wu, Zhenwu Shi, Chengyun Xu, Feng Zhang, Liang Gu, Yanyan Wang, Xiaohong Zhou, C. Peng","doi":"10.1109/3M-NANO.2016.7824970","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824970","url":null,"abstract":"Sol-gel-derived superhydrophobic titanium dioxide(TiO2) thin film on glass was fabricated by using the flame soot layer as a template. After the calcination and the modification of 1,1,1,3,3,3-hexamethyl disilazane, the surface shows a perfect sticky superhydrophobic state with high adhesive force and a water contact angle of 160°as so called “Petal Effect”. The micro/nano-structures of the surface was evaluated byscanning electron microscopy.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125126670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Zeng, X. Chen, Han Wang, Peixuan Wu, Feiyu Fang, Feng Liang, Weijun Ou, Wenkai Yan, Yanming Yang, Y. Zeng, Zhijin Li, Furen Hu
{"title":"The direction and stability control system for near-field electrospinning direct-writing technology","authors":"Jun Zeng, X. Chen, Han Wang, Peixuan Wu, Feiyu Fang, Feng Liang, Weijun Ou, Wenkai Yan, Yanming Yang, Y. Zeng, Zhijin Li, Furen Hu","doi":"10.1109/3M-NANO.2016.7824960","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824960","url":null,"abstract":"Due to the great promise and potential of the near-field electrospinning direct-writing technology, it had played a great role on the field using micro structure like flexible electronic devices, advanced optics, adsorption, filtration material, drug delivery and biomedical. But the printing process is very complex to represent. And the descriptive hydrodynamic equation was not established yet. Furthermore the determination of the process parameters depends by experiences mostly. It is difficult to guarantee the stability of the jet printing process. This article explores the conventional systems of the near-field electrospinning direct-writing technology, especially for the instability of the whip in the printing process. The direction and stability control system is designed for near-field electrospinning direct-writing technology in improving the printing process of the stability and reliability in the production.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133619367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yingjiao Zhai, Jinhua Li, X. Chu, Mingze Xu, F. Jin, X. Fang, Zhipeng Wei, Xiao-hua Wang
{"title":"Preparation of Au-MoS2 electrochemical electrode and investigation on glucose detection characteristics","authors":"Yingjiao Zhai, Jinhua Li, X. Chu, Mingze Xu, F. Jin, X. Fang, Zhipeng Wei, Xiao-hua Wang","doi":"10.1109/3M-NANO.2016.7824931","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824931","url":null,"abstract":"Glucose detection is very important in the areas of medical testing, food processing and bio-analysis. MoS2 microflower modified by Au nanoparticles can effectively improve the electrochemical performance of glucose sensor due to the better electronic conductivity and electro-catalytic activity of precious metal. So we used Au-MoS2 as electrochemical electrode to detect the different concentrations of glucose in 0.1 M phosphate buffered saline (PBS) solution. The experimental results showed that the Au-MoS2 electrochemical electrode had higher response current and electro-catalytic activity than the MoS2 electrode. The Au-MoS2 electrode displayed a good electrocatalytic activity with the high sensitivity of 932μΑ mM−1, and the linear range was 0–15 mM for the detection of glucose. This work makes Au-MoS2 materials apply to the electrochemical sensing applications.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"611 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134401334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Jian, Guo Shuxu, J. Haitao, Gao Fengli, Lu Wenqiang, Wang Deqiang
{"title":"Controllable synthesis of large scale, catalyst-free, lateral ZnO nanowires network","authors":"G. Jian, Guo Shuxu, J. Haitao, Gao Fengli, Lu Wenqiang, Wang Deqiang","doi":"10.1109/3M-NANO.2016.7824964","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824964","url":null,"abstract":"We report a novel method for large scale catalyst-free zinc oxide nanowires (ZnO NWs) network growth on Si substrate using chemical vapor deposition (CVD). The SiO2 layer of the Si substrate is photoetched to SiO2 square pillar array which works as the growth core of urchin-like ZnO NW lump, and the NWs cross over each other forming an integrated network. This method achieves controlled growth of lateral ZnO NW network and allows the in situ nano device fabrication. Meanwhile, the vapor deposition mechanism is discussed and confirmed by contrast experiments along with different growth conditions, which realizes growth on large size substrate. According to the result of Field Emission Scanning Electron Microscope (FE-SEM), the ZnO NWs are wurtzite hexagonal single-crystalline and the network is intact with massive intersection points.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128652881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new type of MEMS accelerometer with up-tuning structure","authors":"Yixuan Guo, Zhong-he Jin, J. Du, Yidong Liu","doi":"10.1109/3M-NANO.2016.7824923","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824923","url":null,"abstract":"In this paper, design, implementation and characterization of a new type of Micro-electromechanical system (MEMS) accelerometer with up-tuning structure is presented. Under some circumstances, the spring of the beam is very fragile and can be easily broken which is unrepairable due to a relatively large acceleration. Up-tuning effect can greatly solve the problem and harden the spring of the beam. Firstly, the theoretical design and working principle of tuning structure are presented. Then, fabrication process and parameters is illustrated. Finally, experiments are conducted. The resonant frequency can be tuned from 386Hz to 407Hz when the tuning voltage changes from 0V to 12V. The equivalent spring constant can be tuned from 65N/m to 72N/m. The linearity of the new type of MEMS accelerometer with up-tuning structure can reach 99.9865%.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126057012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modeling and experimental testing of a composite bridge type amplifier based nano-positioner","authors":"J. Pang, Pengbo Liu, P. Yan, Zhen Zhang","doi":"10.1109/3M-NANO.2016.7824926","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824926","url":null,"abstract":"This paper presents a hybrid modeling method combining the pseudo-rigid-body-model (PRBM) and Euler-Bernoulli beam theory for a composite bridge-type amplifier (CBTA) based nano-positioning stage. Considering the compliance of the input end, the tensile stiffness of the flexure hinge, as well as the effect of external load, the analytical model of the CBTA are established to predict the input stiffness and the input/output displacement amplification ratio based on the hybrid modeling method. The static model of the nano-positioning stage is also developed for the decoupling and guiding mechanisms as the external load of the CBTA. It is shown that the new analysis method can derive a more accurate model of the nano-positioning stage, which is further verified by the finite element analysis (FEA) and experimental results.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126105450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun Zhou, S. Shen, Y. Ye, Yan-Hua Liu, Minghui Luo, Linsen Chen
{"title":"High-performance polarizer based on the double-layer metallic gratings with air-gaps","authors":"Yun Zhou, S. Shen, Y. Ye, Yan-Hua Liu, Minghui Luo, Linsen Chen","doi":"10.1109/3M-NANO.2016.7824938","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824938","url":null,"abstract":"A high-performance polarizer based on the double-layer metallic gratings with air-gaps is theoretically investigated. It is observed that the transmission of the TM polarized light greatly exceeds the double-layer metallic gratings without air-gaps. The electric field distributions are plotted to interpret the physical mechanism. The improvement is attributed to the enhanced coupling between the two metal layers. The transmission efficiency and extinction ratio of the proposed polarizer in terms of different structure parameters and the incident angles are discussed. At the period of 100 nm, the optimized structure can reach an extinction ratio higher than 30 dB and the TM transmission efficiency over 80% until the incident angle is 30o. The study presented here is of great importance in designing and fabricating metallic grating polarizer with better performance.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126136195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Changcheng Shi, Dongshan Wei, Chun-lei Du, Hongliang Cui, Yuting Ma
{"title":"Characterization of Glucosamine and Collagen crystallization by terahertz time-domain spectroscopy","authors":"Changcheng Shi, Dongshan Wei, Chun-lei Du, Hongliang Cui, Yuting Ma","doi":"10.1109/3M-NANO.2016.7824982","DOIUrl":"https://doi.org/10.1109/3M-NANO.2016.7824982","url":null,"abstract":"Terahertz time-domain spectroscopy (THz-TDS) has been demonstrated as a promising solid-state analytical tool which can probe intermolecular interactions through crystal lattice vibrations. However, the current studies commonly investigate the interactions between two biological or pharmaceutical molecules with relatively low molecular weights. The interaction between small biomolecule and biomacromolecule in the crystallization process has not been reported. In this study, THz-TDS was used as a novel technique to characterize the interaction between small biomolecule (Glucosamine) and biomacromolecule (Collagen) in the crystallization process. The absence of THz absorption peak in solvent mixed sample with weight ratio of 1:1 showed the crystallization process of glucosamine was disturbed by collagen. The recurrence of THz absorption peak in solvent mixed sample with weight ratio of 7:1 may be related to the saturation of interaction between glucosamine and collagen. The dissolving and lyophilizing processes were validated to hardly affect the crystal formation of glucosamine. This study further demonstrates THZ-TDS has the capability to characterize the interaction between small biomolecule and biomacromolecule in solid-state.","PeriodicalId":273846,"journal":{"name":"2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128836199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}