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Corrigendum to “Mechanism of charge self-reversal nano-nutrient delivery system to overcome the mucosal barrier” [Chem. Eng. J. 499 (2024) 155594] “电荷自反转纳米营养输送系统克服粘膜屏障的机制”的勘误[化学]。Eng。J. 499 (2024) 155594]
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159650
Yaqing Bian, Tongliang Yang, Zihan Qu, Tiantian Zhang, Cheng Yang, Guiyun Chen, Ye Chen, Shuhong Li
{"title":"Corrigendum to “Mechanism of charge self-reversal nano-nutrient delivery system to overcome the mucosal barrier” [Chem. Eng. J. 499 (2024) 155594]","authors":"Yaqing Bian, Tongliang Yang, Zihan Qu, Tiantian Zhang, Cheng Yang, Guiyun Chen, Ye Chen, Shuhong Li","doi":"10.1016/j.cej.2025.159650","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159650","url":null,"abstract":"The authors regret the omission of the grant number and details in the paper. Below are the grant details:","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"81 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formaldehyde-free wood bio-adhesives from sewage sludge: Role of ammonium polyphosphate 从污水污泥中提取无甲醛木材生物胶粘剂:聚磷酸铵的作用
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159805
Han-Song Zhu, Yi Tan, Xiao-Bin Dong, Fan Gao, Huan Yang, Zhi-Xiang Xu, Rafael Luque
{"title":"Formaldehyde-free wood bio-adhesives from sewage sludge: Role of ammonium polyphosphate","authors":"Han-Song Zhu, Yi Tan, Xiao-Bin Dong, Fan Gao, Huan Yang, Zhi-Xiang Xu, Rafael Luque","doi":"10.1016/j.cej.2025.159805","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159805","url":null,"abstract":"A novel formaldehyde-free wood bio-adhesive with remarkable flame resistance has been developed using hydrochar derived from sewage sludge (SS). The extracellular polymeric substances in SS are further broken down during hydrothermal carbonization via catalysis by layered double oxides (LDO). This process leads to more organic matter transferring into the aqueous phase and the formation of low-molecule-weight compounds. Simultaneously, LDO is converted into layered double hydroxides (LDH) as a flame-retardant. However, due to the formation of low-molecule-weight compounds, the resulting bio-adhesive exhibited poor wet shear strength (0.37 MPa). To address this issue, ammonium polyphosphate (APP) was introduced into the formulation, significantly improving the bio-adhesive’s wet shear strength to 1.00 MPa, which meets the Chinese national standard GB/T 9846–2015 (≥0.7 MPa). The enhanced performance is attributed to the reaction between APP and the organic matter on the surface of hydrochar to form macromolecular compounds. The combination of LDH and APP imparts excellent flame-retardant properties to the bio-adhesive, making it a significant advancement in the valorization of hydrochar from SS. This research presents a novel and sustainable approach to converting waste materials into valuable products.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"10 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In2O3 modification mitigates Jahn-Teller effect in LiMn2O4 enhancing lithium extraction efficiency and stability In2O3改性降低了LiMn2O4中的Jahn-Teller效应,提高了锂萃取效率和稳定性
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159815
Linlin Chen, Linjing Fan, Delin Lan, Jun Gu, Chen Xiaojun, Haiyan Ji, Yanhong Chao, Peiwen Wu, Wenshuai Zhu
{"title":"In2O3 modification mitigates Jahn-Teller effect in LiMn2O4 enhancing lithium extraction efficiency and stability","authors":"Linlin Chen, Linjing Fan, Delin Lan, Jun Gu, Chen Xiaojun, Haiyan Ji, Yanhong Chao, Peiwen Wu, Wenshuai Zhu","doi":"10.1016/j.cej.2025.159815","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159815","url":null,"abstract":"The rapid growth of lithium-ion batteries has intensified the demand for lithium, requiring the development of efficient selective extraction methods from salt-lake brines with high magnesia-lithium ratios. This work presents a novel composite electrode material, In<sub>2</sub>O<sub>3</sub>-modified LiMn<sub>2</sub>O<sub>4</sub> (In-LMO), synthesized through solvent evaporation coupled with the calcination method, for Selective electro-chemical extraction of lithium. The introduction of In<sub>2</sub>O<sub>3</sub> effectively modulates the local charge state within the LMO structure, resulting in an increased proportion of Mn<sup>VI</sup> and mitigating the detrimental Jahn-Teller effect, which typically compromises stability during lithium extraction. Characterizations confirm that the anchoring of In<sub>2</sub>O<sub>3</sub> also enhances the stability of lattice oxygen in LMO. The optimized 1In-LMO electrode material demonstrates impressive lithium extraction capacities of 20.18 mg/g in simulated brine, with minimal Mn dissolution and excellent cycling stability. Notably, in the mother liquor of Li<sub>2</sub>CO<sub>3</sub> with a high Na/Li ratio (44.8), the system achieves a selective lithium release capacity of 21.33 mg/g, while in the challenging West Taijinar salt lake brine with elevated Mg/Li ratios, a selective extraction capacity of 26.75 mg/g was attained. These results underscore the industrial potential of the 1In-LMO electrode material, positioning it as a promising candidate for sustainable lithium recovery from complex brine sources.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"50 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermal-responsive microgels incorporated PVA composite hydrogels: Integration of two-stage drug release and enhanced self-healing ability for chronic wound treatment 热响应微凝胶加入PVA复合水凝胶:整合两阶段药物释放和增强自愈能力,用于慢性伤口治疗
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159813
Zeying Liu, Huixia Li, Yalin Huang, Jie Li, Ruiying Dong, Xue Yun, Yuqian Ren, Xiaonan Liu, Hui Hui, Lei Wu, Ziwei Lu, Yali Cui, Kai Hua
{"title":"Thermal-responsive microgels incorporated PVA composite hydrogels: Integration of two-stage drug release and enhanced self-healing ability for chronic wound treatment","authors":"Zeying Liu, Huixia Li, Yalin Huang, Jie Li, Ruiying Dong, Xue Yun, Yuqian Ren, Xiaonan Liu, Hui Hui, Lei Wu, Ziwei Lu, Yali Cui, Kai Hua","doi":"10.1016/j.cej.2025.159813","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159813","url":null,"abstract":"Thermal-responsive microgels constructed based on poly(ethylene glycol) methacrylates (PMO) are promising in the biomedical field owing to their biocompatibility and tunable low critical solution temperature (LCST). In this study, we prepared the composite microgels (PMO-carboxymethyl cellulose (CMC)) with enhanced thermal-responsive properties by simply mixing CMC with PMO microgels. The composite microgels exhibited increased particle size, hydrophilic performance, and temperature-dependent optical properties. The drug-loaded PMO microgels showed the ability of temperature-controlled drug release. Meanwhile, CMC modification increased drug loading capacity and reduced the burst release of the composite microgels. The microgels were further embedded in borax cross-linked poly(vinyl alcohol) (PVA) hydrogels to prepare a thermal-responsive composite hydrogels. The thermal-responsive properties of the microgels were unhindered by the surrounding hydrogel matrix. Compared with PMO microgels, the incorporation of PMO-CMC microgels led to a denser honeycomb microstructure and excellent self-healing ability. These composite hydrogels exhibited a two-stage drug release of thermal-responsive drug release from microgels and prolonged drug delivery from PVA matrix. The <em>in vivo</em> chronic wound model studies demonstrated that the drug-loaded PMO-CMC-PVA hydrogels contributed to a better therapeutic effect for chronic wound healing owing to their desired properties. This thermal-responsive composite hydrogels provided a promising treatment for complicated wound management and can be extended for other applications in the biomedical field","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"57 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual Channel passivation enhancing stable perovskite Light-Emitting diodes 双通道钝化增强稳定的钙钛矿发光二极管
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159796
Shao-Qi Wang, Wei Yang, Yu Xia, Bin Wang, Nan Li, Lei Huang, Xin Chen, Yu-Han Li, Jing Chen, Chun-Hao Chen, Zhao-Kui Wang
{"title":"Dual Channel passivation enhancing stable perovskite Light-Emitting diodes","authors":"Shao-Qi Wang, Wei Yang, Yu Xia, Bin Wang, Nan Li, Lei Huang, Xin Chen, Yu-Han Li, Jing Chen, Chun-Hao Chen, Zhao-Kui Wang","doi":"10.1016/j.cej.2025.159796","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159796","url":null,"abstract":"Perovskite light-emitting diodes (PeLEDs) still faces the challenges such as poor film morphology and inefficient energy transfer from the small-n phase to the large-n phase leading to rapid efficiency degradation and instability in high temperature. To address these issues, herein, chlormezanone was employed to modify the perovskite film. Combined beneficial points were obtained including improved film morphology, reduced luminescence quenching, enhanced phase distribution and energy transfer by suppressing small-n phases, and defect mitigation at grain boundaries/interfaces via passivation groups (C = O, S = O). Consequently, the fabricated sky-blue PeLEDs delivered an external quantum efficiency of 10.14 % and an operating lifetime (<em>T</em><sub>50</sub>) of 23.1 min, which was twice as long as the control device. This developed strategy significantly enhanced the stability while maintain excellent efficiency, providing a solid foundation for future investigation.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"18 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifunctional MnO2 nanosheet based DNA tetrahedron- photosensitizer nanoplatform for gene-photodynamic modulation 基于多功能二氧化锰纳米片的DNA四面体光敏剂纳米平台的基因光动力调制
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159807
Yanlin Zheng, Fei Li, Xiaohui Zhu, Min Wang, Yuantao Wen, Tao Zeng, Wukun Zhong, Chao Xing, Chunhua Lu
{"title":"Multifunctional MnO2 nanosheet based DNA tetrahedron- photosensitizer nanoplatform for gene-photodynamic modulation","authors":"Yanlin Zheng, Fei Li, Xiaohui Zhu, Min Wang, Yuantao Wen, Tao Zeng, Wukun Zhong, Chao Xing, Chunhua Lu","doi":"10.1016/j.cej.2025.159807","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159807","url":null,"abstract":"Photodynamic therapy (PDT) holds great promise for treating various types of cancer. However, its clinical advancement is hindered by the intrinsic hypoxic tumor microenvironment, which reduces PDT efficacy, and safety concerns related to the biological specificity of photosensitizers. Here we constructed a MnO<sub>2</sub> nanosheet based DNA tetrahedron-photosensitizer (TMPyP4) nanoplatform (TPM), which integration with tumor targeting (aptamer), gene drugs (DNAzyme) and photosensitizer agents for enhanced PDT. Once the TPM entered cancer cells through aptamer targeting, the MnO<sub>2</sub> nanosheet reacts with endogenous acidic and H<sub>2</sub>O<sub>2</sub> to generate Mn<sup>2+</sup> and oxygen (O<sub>2</sub>), thereby alleviating the tumor hypoxic. Subsequently, TMPyP4 further converts the generated O<sub>2</sub> into singlet oxygen (<sup>1</sup>O<sub>2</sub>) under near-infrared light, enhancing PDT efficacy both in vitro and in vivo. Specifically, the generated Mn<sup>2+</sup> activates the DNAzyme and accelerate tumor target mRNA cleavage, resulting in effective PDT-gene synergistic therapy for tumors. This work offers novel perspectives on advancing precise and highly effective gene-PDT systems.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"45 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficient hydrolytic desulfurization of carbon disulfide using palladium-anchored bipyridine and phenanthroline-based organic polymers under mild conditions 钯锚定联吡啶和邻菲罗啉基有机聚合物在温和条件下高效水解脱硫二硫化碳
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159606
Qing Huang, Xing-Yu Chen, Yu-Peng Dai, Guo-Kang Yang, Ping Shang, Xuan-Feng Jiang
{"title":"Efficient hydrolytic desulfurization of carbon disulfide using palladium-anchored bipyridine and phenanthroline-based organic polymers under mild conditions","authors":"Qing Huang, Xing-Yu Chen, Yu-Peng Dai, Guo-Kang Yang, Ping Shang, Xuan-Feng Jiang","doi":"10.1016/j.cej.2025.159606","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159606","url":null,"abstract":"The design and development of innovative catalysts have emerged as a significant research focus in the field of catalytic hydrolysis of sulfur-containing small molecules. In this study, two nitrogen-rich microporous polymer catalysts with anchored palladium (II) active sites were synthesized through a post-coordination modification technique applied to a two-dimensional organic porous polymer matrix. The amorphous morphology of these porous catalysts offers a wide range of pore sizes and adsorption capacity, facilitating the efficient adsorption of carbon disulfide (CS<sub>2</sub>) molecules and subsequent catalytic desulfurization within confined spaces. The hydrolytic desulfurization efficiency of two Pd-containing organic polymer porous catalysts reached up to 12.69 μmol/g/h, which represents a 4.1-fold increase compared to the efficiency of small molecule complex catalysts with the same palladium content reported in earlier studies under the homogeneous condition. Through the incorporation of concentrated nitric acid (HNO<sub>3</sub>) as a sacrificial agent, the efficiency of catalytic desulfurization increased by a factor of 23.2. Additionally, the catalyst was activated and reused multiple times. Density functional theory (DFT) calculation results have validated the mechanism and reaction pathway involved in the cleavage of C=S bond induced by the nucleophilic attack of hydroxide (OH<sup>–</sup>) ions. These results offer novel perspectives and methods for the design and fabrication of heterogeneous supported metal–organic porous polymer catalysts.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"38 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Up-concentration of organic matter from municipal wastewater by coagulation coupled with active coke adsorption to improve carbon capture and anaerobic methanogenesis efficiency 混凝-活性焦炭吸附法提高城市污水中有机物浓度,提高碳捕获和厌氧产甲烷效率
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159853
Ying An, Yanhua Xu, Chen Tang, Xingzhi Du, Zihang Ma, Rui Tang, Bin Zhou, Zhan Qiu, Zhen Zhou
{"title":"Up-concentration of organic matter from municipal wastewater by coagulation coupled with active coke adsorption to improve carbon capture and anaerobic methanogenesis efficiency","authors":"Ying An, Yanhua Xu, Chen Tang, Xingzhi Du, Zihang Ma, Rui Tang, Bin Zhou, Zhan Qiu, Zhen Zhou","doi":"10.1016/j.cej.2025.159853","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159853","url":null,"abstract":"Up-concentration of organic matter plays a crucial role in recovering carbon resources and energy from municipal wastewater, and the capture of dissolved organic matter during coagulation process is essential for enhancing carbon separation and recovery efficiency. In this study, we employed active coke adsorption combined with ferric chloride (FeCl<sub>3</sub>) coagulation process to enhance organic matter capture efficiency from municipal wastewater. Subsequently, the anaerobic methanation performance and microbial mechanism of the resulting carbon-rich sludge were investigated. Results indicated that the combined process increased organic matter capture efficiency by 0.8 % – 29.2 % compared to single coagulation treatment. Prepositive active coke adsorption within the FeCl<sub>3</sub> coagulation process achieved superior carbon capture performance compared to synchronous and postpositive configurations. Optimal dosage for adsorption-coagulation process using FeCl<sub>3</sub> of 43.65 mg Fe/L and active coke of 7.6 mg/L was obtained by applying an integrative response surface methodology (RSM) coupled nonlinear programming approach under effluent COD constraint of 48 mg/L. The integrative optimization resulted in a 47.9 % cost reduction compared to the RSM optimized condition. Anaerobic experiments demonstrated that utilization of active coke adsorption boosted organic matter capture, resulting in a 22.1 % increase in methane yield (CH<sub>4</sub>/m<sup>3</sup> wastewater) compared to using coagulation alone. Microbial community structure analysis showed that active coke promoted enrichment of acetoclastic methanogen and electroactive microorganisms. These findings posed ideas and technical support for strengthening carbon separation and recovery efficiency from municipal wastewater.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"11 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organelle remodeling enhances mitochondrial ATP disruption for blocking neuro-pain signaling in bone tumor therapy 骨肿瘤治疗中细胞器重塑增强线粒体ATP破坏阻断神经痛信号
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159825
Qianyi Zhang, Hongjun Zhuang, Xiaofei Wen, Yonghui Su, Jiamian Wang, Hao Qin, Jiaqian Wang, Zhaoshui Shangguan, Yiqun Ma, Jian Dong, Bo Tian, Xilei Li
{"title":"Organelle remodeling enhances mitochondrial ATP disruption for blocking neuro-pain signaling in bone tumor therapy","authors":"Qianyi Zhang, Hongjun Zhuang, Xiaofei Wen, Yonghui Su, Jiamian Wang, Hao Qin, Jiaqian Wang, Zhaoshui Shangguan, Yiqun Ma, Jian Dong, Bo Tian, Xilei Li","doi":"10.1016/j.cej.2025.159825","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159825","url":null,"abstract":"Cancer neuroscience has revealed the pivotal role of neural pathways in tumor progression and cancer-associated pain, particularly in bone metastases. To address both tumor growth and pain, we developed a novel nanomedicine strategy that targets mitochondrial dysfunction in cancer cells. The engineered H-MnCa/3MA-ALD nanoparticle system combines hollow mesoporous manganese-calcium (H-MnCa) nanoparticles functionalized with alendronate (ALD) for bone targeting, and loaded with 3-Methyladenine (3MA) to inhibit autophagy. This system disrupts mitochondrial ATP production, exploiting the inherent vulnerability of mitochondria to oxidative stress, and enhances reactive oxygen species (ROS) generation. The elevated ROS selectively induces cancer cell death while also reducing the secretion of nerve growth factor (NGF). This dual-action mechanism not only inhibits tumor growth and metastasis but also alleviates cancer-induced bone pain by downregulating neuro-pain mediators such as p-STAT-3 and NGF. This approach overcomes traditional chemodynamic therapy (CDT) limitations, ensuring targeted mitochondrial damage and apoptosis while preventing protective mitophagy. <em>In vivo</em> studies further confirm that H-MnCa/3MA-ALD provides effective tumor eradication and pain relief, offering a comprehensive solution for both cancer progression and pain management.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"24 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-responsive circularly polarized luminescence micro-patterns with high figure of merit towards multi-dimensional data encoding 面向多维数据编码的多响应圆偏振发光微图
IF 15.1 1区 工程技术
Chemical Engineering Journal Pub Date : 2025-01-22 DOI: 10.1016/j.cej.2025.159821
Li Wen, Peng Yang, Shunpin Mo, Di Wang, Nana Sheng, Xiangxiang Xu, Hongli Zhang, Hongbo Lu, Gang Zou
{"title":"Multi-responsive circularly polarized luminescence micro-patterns with high figure of merit towards multi-dimensional data encoding","authors":"Li Wen, Peng Yang, Shunpin Mo, Di Wang, Nana Sheng, Xiangxiang Xu, Hongli Zhang, Hongbo Lu, Gang Zou","doi":"10.1016/j.cej.2025.159821","DOIUrl":"https://doi.org/10.1016/j.cej.2025.159821","url":null,"abstract":"Circularly polarized luminescence (CPL) materials are emerging as promising tools for multi-dimensional data encoding due to their inherent chiroptical information dimension, facile reading and reduced cost. In classic cholesteric liquid crystal (LC) systems, a giant dissymmetry factor of CPL (<em>g</em><sub>lum</sub> &gt; 1.2) can be achieved based on the selective transmission mechanism, however, this comes with a nearly 50 % loss in luminescence efficiency (φ), resulting in lower figure of merit (FOM). Developing novel CPL materials with high <em>g</em><sub>lum</sub> and FOM values, multi-responsivity, and arbitrary patterning ability is crucial for meeting the demands of practical applications. Herein, we proposed a general twisted-stacking strategy to break the bottleneck for CPL materials and unexpectedly achieving 95 % luminescence efficiency, <em>g</em><sub>lum</sub> of 1.28 and high FOM value up to 1.22, much higher than most reported CPL systems. The bottom-layer photo-polymerizable nematic liquid crystal (NLC) endows not only excellent polarized luminescence with multi-responsivity but also arbitrary patterning capabilities. Simultaneously, the top-layer transparent oriented poly (vinyl alcohol) (PVA) layer serves as the phase retardation, resulting in the generation of CPL with a high <em>g</em><sub>lum</sub>, while φ is preserved without diminishing. By applying external light, voltage and heat, the CPL signal within the micropatterns can be precisely regulated, allowing for the implementation of high-level anti-counterfeiting and multi-dimensional information encryption.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"189 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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