Chemical Engineering Journal最新文献_第4页

Ultrasound-activated piezo-spark navigator hydrogel for mandibular defect repair 超声激活压电火花导航仪水凝胶用于下颌缺损修复

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183047

Shidian Ran, Liwen Zheng, Linyu Xue, Minyu Han, Zhengnong Guo, Sixue Chen, Ziyan Wang, Chang Liu, Yuxin Zhang, Jiajun Chen, Xingrui Yan, Xiaorui Wei, Jindie Huang, Peng Xue, Hongmei Zhang, Mengqin Gu

{"title":"Ultrasound-activated piezo-spark navigator hydrogel for mandibular defect repair","authors":"Shidian Ran, Liwen Zheng, Linyu Xue, Minyu Han, Zhengnong Guo, Sixue Chen, Ziyan Wang, Chang Liu, Yuxin Zhang, Jiajun Chen, Xingrui Yan, Xiaorui Wei, Jindie Huang, Peng Xue, Hongmei Zhang, Mengqin Gu","doi":"10.1016/j.cej.2026.183047","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183047","url":null,"abstract":"The infected bone defects remain challenging to repair due to the lack of biomaterials that can sequentially eradicate bacteria and drive robust osteogenesis. Here, a “Piezo-Spark” bone regeneration navigator strategy is established on a multifunctional piezoelectric hydrogel (Pt-ZnO NPs/SDF-1α@GelMA/ODex, PZS@GO), composed of gelatin methacrylate (GelMA)/oxidized dextran (ODex) double-network matrix (GO) loaded with platinum‑zinc oxide nanoparticles (Pt-ZnO NPs) and stromal cell-derived factor-1α (SDF-1α). The short rodlike Pt-ZnO NPs possess a narrow bandgap (3.17 eV) and a large piezoelectric d33 coefficient of (83 ± 4.36) pC/N. Thus, under ultrasound (US) irradiation, PZS@GO shows enhanced piezoelectric output, which triggers the efficient elimination of bacteria and “purify the route” within the infected bone defect. Meanwhile, the hydrogel provides sustained release of SDF-1α, acting as a homing signal to recruit rat bone marrow mesenchymal stem cells (rBMSCs) toward the lesion. Subsequently, the persistent piezoelectric signals produced by US-activated Pt-ZnO NPs guide these recruited cells toward osteogenic differentiation. <ce:italic>In vivo</ce:italic>, US + PZS@GO eliminates infection and markedly improves bone volume and microarchitectural parameters. To our knowledge, this work provides a paradigm of a piezoelectric hydrogel integrating antibacterial activity, cell recruitment, and osteogenesis to optimize mandibular osteogenesis regeneration, highlighting the potential of the “Piezo-Spark” bone regeneration navigator concept for regenerative repair of infected bone defects.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"73 1","pages":"183047"},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green emulsification of basil essential oil microcapsules using sodium lignosulfonate toward UV-shielding and antimicrobial active food packaging 木质素磺酸钠绿色乳化罗勒精油微胶囊的防紫外线和抗菌活性食品包装

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183044

Lina Chen, Chenhao Li, Siyi Chen, Shusheng Chen, Yusheng Wang, Xueqing Qiu, Junbing He

{"title":"Green emulsification of basil essential oil microcapsules using sodium lignosulfonate toward UV-shielding and antimicrobial active food packaging","authors":"Lina Chen, Chenhao Li, Siyi Chen, Shusheng Chen, Yusheng Wang, Xueqing Qiu, Junbing He","doi":"10.1016/j.cej.2026.183044","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183044","url":null,"abstract":"Active food packaging incorporating plant essential oils (EOs) offers a sustainable alternative to synthetic preservatives, but industrial adoption is limited by the inherent volatility of EOs and the environmental footprint of petroleum-based emulsifiers in conventional microencapsulation. Herein, we report a green emulsification strategy employing sodium lignosulfonate (SL), an industrial byproduct, as a multifunctional emulsifier to fabricate basil essential oil microcapsules (BEOMC) via interfacial polymerization. The resulting BEOMC exhibit uniform spherical morphology, relatively high core content, and enhanced thermal stability. Subsequent incorporation of BEOMC into a polyvinyl alcohol (PVA) matrix constructs multifunctional active packaging films. The optimized films exhibit exceptional UV-shielding capability with nearly zero UV transmittance while maintaining high optical transparency (74.5%) and robust mechanical properties. Furthermore, the films demonstrate a characteristic biphasic release profile that ensures rapid initial antimicrobial activity and prolonged antimicrobial efficacy, achieving antibacterial rates of 99.3% against <ce:italic>Escherichia coli</ce:italic> and 97.9% against <ce:italic>Staphylococcus aureus</ce:italic>. Practical evaluations reveal that these films significantly retard fruit decay, extending the shelf life of strawberries to 9 days, substantially outperforming neat PVA films (2 days) and unpackaged controls (1 day). This work opens a viable route not only for high-value utilization of industrial lignin but also for next-generation sustainable and active food packaging systems.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"34 1","pages":"183044"},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the origin of cascading degradation in LiFePO4 – lithium metal batteries 揭示了LiFePO4 -锂金属电池级联降解的起源

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183087

Midam Lee, Jaehyung Shin, Heejoo Park, Wonyoung Song, Seungeun Yu, Oh.B. Chae, Junghyun Choi, Jihyun Jang

{"title":"Unveiling the origin of cascading degradation in LiFePO4 – lithium metal batteries","authors":"Midam Lee, Jaehyung Shin, Heejoo Park, Wonyoung Song, Seungeun Yu, Oh.B. Chae, Junghyun Choi, Jihyun Jang","doi":"10.1016/j.cej.2026.183087","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183087","url":null,"abstract":"Lithium iron phosphate (LFP) is widely used in electric vehicles and energy storage systems because of its low cost and excellent cyclability. To address the limited energy density of LFP-based cells, Li || LFP batteries with lithium-metal anodes have attracted significant interest. However, unlike conventional graphite || LFP cells, Li || LFP systems frequently exhibit sudden death during long-term cycling. In this work, we systematically investigate the mechanism responsible for this failure. We reveal that unexpected closed-loop structures, initiated by the high reactivity of lithium metal and accelerated by particle cracking from LFP degradation, drive rapid performance decay. These coupled effects decrease Coulombic efficiency and increase cell impedance. Our findings highlight the critical interplay between lithium metal reactivity and LFP structural degradation, and we demonstrate that optimized electrolytes, electrode microstructural control, and interfacial engineering can effectively mitigate sudden death and improve the performance of Li || LFP batteries.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"15 1","pages":"183087"},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial lightning driven teslaphoresis plasma remodeling of NiFe layered double hydroxide for solar powered seawater splitting 人工闪电驱动NiFe层状双氢氧化物等离子体重塑用于太阳能海水分裂

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.182982

Jia-He Li, Tian-You Wu, Ru-Qian Li, Jia-Ying Lin, Ze-Yu Zhang, Dian Li, Guanghui Chen, Qing-Xiao Tong, Jing-Xin Jian

{"title":"Artificial lightning driven teslaphoresis plasma remodeling of NiFe layered double hydroxide for solar powered seawater splitting","authors":"Jia-He Li, Tian-You Wu, Ru-Qian Li, Jia-Ying Lin, Ze-Yu Zhang, Dian Li, Guanghui Chen, Qing-Xiao Tong, Jing-Xin Jian","doi":"10.1016/j.cej.2026.182982","DOIUrl":"https://doi.org/10.1016/j.cej.2026.182982","url":null,"abstract":"Solar-driven seawater splitting offers a sustainable pathway to green hydrogen, yet practical implementation requires catalysts that combine high activity, chloride resilience, and scalability. A rapid, ambient-condition “artificial lightning” strategy is demonstrated using Tesla coil-generated plasma and electric field to reconfigure both the morphology and electronic structure of NiFe layered double hydroxides (LDH) for seawater splitting. This minute-scale process drives the hierarchical self-assembly of nanoflowers and creates oxygen vacancies, which synergistically optimize charge transfer and active sites. The engineered <ce:italic>T</ce:italic>-Ce(OH)<ce:inf loc=\"post\">3</ce:inf>/NiFe-LDH electrode achieves industrial-level current densities (> 1 A cm<ce:sup loc=\"post\">−2</ce:sup>), an overpotential of 150 mV at 100 mA cm<ce:sup loc=\"post\">−2</ce:sup> for the oxygen evolution reaction (OER), and a stability of 571 h at 1000 mA cm<ce:sup loc=\"post\">−2</ce:sup> for seawater splitting. When integrated into a photovoltaic–electrocatalysis system, the electrode delivers a solar-to‑hydrogen efficiency of 13.95% in natural seawater and maintains continuous hydrogen production over 30 days under natural sunlight. These results demonstrate that non-equilibrium plasma generated by a Tesla coil can simultaneously engineer nanoarchitecture and defect chemistry, providing a route to high-performance seawater-splitting electrodes without prolonged thermal or wet-chemical processing.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"33 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recoverable polyanion bead catalysts for selective depolymerization and fiber recovery from polyester composites 聚酯复合材料选择性解聚和纤维回收的可回收聚阴离子头催化剂

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183070

Yongsu Kim, Dong Jun Lee, Mira Shin, Renhua Deng, Jeyoung Park, Hyeong Jun Kim

{"title":"Recoverable polyanion bead catalysts for selective depolymerization and fiber recovery from polyester composites","authors":"Yongsu Kim, Dong Jun Lee, Mira Shin, Renhua Deng, Jeyoung Park, Hyeong Jun Kim","doi":"10.1016/j.cej.2026.183070","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183070","url":null,"abstract":"Polyesters are widely used as composites in many commercial products, such as textiles, electronics, and automotive components, yet their multicomponent nature complicates separation processes and renders recycling impractical. Herein, glycolysis of polyester composites with macroporous polyanion bead catalysts enables component-selective depolymerization of the polyester matrix, enabling facile recovery of the monomer product, non-polyester components, and the catalyst itself for reuse. Glass-fiber-reinforced PET and PBT are efficiently depolymerized, affording bis(2-hydroxyethyl) terephthalate (BHET) yields of 95.8 ± 2.0% and 90.5 ± 2.6%, respectively. The non-corrosive nature of the glycolysis reaction condition preserves the glass fibers in both composition and length. Moreover, the macroscopic bead form of the catalyst allows simple filtration and density-based fractionation to cleanly separate reinforcing fibers and catalyst, and the recovered catalyst is reused over five cycles with an average BHET yield of 93.3 ± 4.3%. The polyanion bead-catalyst glycolysis extends to post-consumer polyester composites. Polyester/cotton textiles (65:35 wt%) give 98.9% depolymerization conversion and 93.7% monomer yield, with cotton morphology and chemistry preserved. Intact glass-fiber-reinforced polyester parts from automotive and electronics likewise yield both the polyester monomer and the reinforcing fibers. Scaling up further, a single ~40 g automobile polyester composite part affords 35.1 g of purified BHET and 10.8 g of clean glass fibers, showing that mechanically intractable composites can be recycled without grinding. Glycolysis with recoverable polyanion bead catalyst enables component-selective depolymerization of polyester matrices in composites, recovering catalyst, fiber, and monomer—turning unrecyclable composites into recoverable feedstock.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"1 1","pages":"183070"},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-strong, highly stretchable, and conductive ionic elastomers with tailored dynamic networks for ambient self-healing flexible sensors 超高强度、高拉伸性和导电性离子弹性体，具有定制的动态网络，可用于环境自修复柔性传感器

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183077

Xinlei Xiao, Da Song, Xiuyu Zhang

{"title":"Ultra-strong, highly stretchable, and conductive ionic elastomers with tailored dynamic networks for ambient self-healing flexible sensors","authors":"Xinlei Xiao, Da Song, Xiuyu Zhang","doi":"10.1016/j.cej.2026.183077","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183077","url":null,"abstract":"Flexible ionically conductive elastomers combining extraordinary mechanical toughness, high stretchability, superior ionic conductivity, and ambient self-healing capability represent ideal candidates for next-generation wearable electronics. However, the intrinsic trade-off between mechanical strength and dynamic bond reversibility remains a fundamental challenge in this field. Here, a tailored dynamic network strategy is proposed to construct an ultra-strong, super-elastic, and highly conductive ionically conductive elastomer. By integrating a microphase-separated dual-soft-segment matrix with dynamic covalent disulfide linkages and multiple hydrogen-bonding domains, a multiscale energy-dissipation network interpenetrated with bicontinuous-like microphase-separated domains that facilitate ion transport is established. The resulting material overcomes traditional performance bottlenecks, exhibiting an ultimate tensile stress of 21.78 MPa, a strain at break of 2167%, an ultra-high toughness of 160.3 MJ/m<ce:sup loc=\"post\">3</ce:sup>, and an exceptional fracture energy of 84.7 kJ/m<ce:sup loc=\"post\">2</ce:sup>. Concurrently, the unobstructed migration of ionic liquid ([EMIM][TFSI]) within the microphase channels endows the material with a superior ionic conductivity of 0.00811 S/m and a highly stable gauge factor (GF = 1.99). Crucially, the synergistic chain-segment mobility of the dual soft segments, combined with the reversible exchange of dynamic interfacial bonds, enables autonomous room-temperature self-healing without any external stimuli. As a proof of concept, flexible strain sensors fabricated from this ionically conductive elastomer display exceptional sensitivity and durability in real-time monitoring of complex human joint motions. This tailored dynamic network design strategy offers a powerful paradigm for developing next-generation autonomous self-healing, high-performance soft ionic electronics.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"14 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D-printed multimodal flexible sensor with bionic lily structure for physics-explainable decoupling of pressure and torsion 具有仿生百合结构的3d打印多模态柔性传感器，用于物理解释的压力和扭转解耦

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183078

Hongxuan Zhao, Fawei Guo, Guangmeng Ma, Ziwei Deng, Ziyue Yu, Yin Feng, Yongsheng Wang, Xingyu Xu, Yu Long

{"title":"3D-printed multimodal flexible sensor with bionic lily structure for physics-explainable decoupling of pressure and torsion","authors":"Hongxuan Zhao, Fawei Guo, Guangmeng Ma, Ziwei Deng, Ziyue Yu, Yin Feng, Yongsheng Wang, Xingyu Xu, Yu Long","doi":"10.1016/j.cej.2026.183078","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183078","url":null,"abstract":"Decoupling pressure and torsion in a single soft sensor remains challenging because both inputs deform the same elastomer and generate coupled electrical signals. Different pressure–torsion states may therefore produce similar capacitance responses, making reliable separation difficult when only conventional capacitance signals are used. Here, we report a 3D-printed bionic lily capacitive sensor that introduces a stable dielectric-loss signal for pressure–torsion decoupling. The sensor consists of an ion-rich elastomer, pressure-sensing electrodes, semicircular torsion electrodes, and grounded shielding layers. Grounded shielding constrains fringe-field coupling and produces a reproducible angle-dependent dissipation response in the torsion channel. Equivalent-circuit analysis characterizes the measured complex response, while COMSOL simulations and shielding-control experiments support the interpretation of the torsion-dependent electrical behavior. By combining capacitance signals with the shield-regulated dielectric-loss signal, a low-order polynomial model decouples pressure and torsion across 56 coupled states spanning 0–0.35 N and 0°–90°. The model achieved calibration <ce:italic>R</ce:italic><ce:sup loc=\"post\">2</ce:sup> values of 0.91 and 0.98 for pressure and torsion, respectively. The three electrical observables maintained repeatable responses over 2000 coupled-loading cycles. A robotic gripper test further demonstrates simultaneous normal-force and twisting-angle reconstruction under coupled contact. This work provides a simple and physically interpretable strategy for reducing crosstalk in flexible capacitive sensors, with potential applications in robotic tactile sensing, wearable interfaces, and multimodal soft sensing systems.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"33 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A hollow copper-free nanomedicine harnesses endogenous copper stress for synergistic cuproptosis/ferroptosis/apoptosis in esophageal cancer 一种中空无铜纳米药物利用内源性铜应激协同食管癌铜沉降/铁沉降/细胞凋亡

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183092

Yi Lu, Yuqi Qiao, Wanyun Li, Xueyun Zhang, Kouyun Zhu, Yun Dong, Mingliang Pei, Rui Xu

{"title":"A hollow copper-free nanomedicine harnesses endogenous copper stress for synergistic cuproptosis/ferroptosis/apoptosis in esophageal cancer","authors":"Yi Lu, Yuqi Qiao, Wanyun Li, Xueyun Zhang, Kouyun Zhu, Yun Dong, Mingliang Pei, Rui Xu","doi":"10.1016/j.cej.2026.183092","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183092","url":null,"abstract":"Cuproptosis has emerged as a promising copper-dependent cell death pathway for cancer therapy, yet most existing cuproptosis-inducing nanomedicine rely on exogenous copper delivery, which raises concerns regarding copper leakage and off-target toxicity. Herein, we developed a multifunctional copper-free nanomedicine, ZID@PDA/DOX, for synergistic esophageal cancer (EC) therapy through the combined activation of cuproptosis/ferroptosis and apoptosis. In this system, the copper efflux inhibitor DC_AC50 was encapsulated into MOF-based nanoparticles (ZID) to improve stability and achieve acid-responsive intracellular release. Subsequently, hollow polydopamine-coated nanoparticles (ZID@PDA) were fabricated under ammonia conditions, which improved colloidal stability and provided binding sites for doxorubicin (DOX) loading, yielding ZID@PDA/DOX. Following cellular internalization, ZID@PDA/DOX underwent acid-triggered decomposition, resulting in drug release and polyphenol fragment generation. Among them, DC_AC50 blocked copper efflux to promote intracellular copper ions accumulation, while phenolic fragments derived from the polydopamine shell further anchored intracellular copper ions. Together, these processes amplified cuproptosis and coordinately induced ferroptosis though GSH depletion. Meanwhile, the released DOX triggered apoptosis through DNA damage-associated signaling pathways. By combining copper efflux blockade with intracellular copper anchoring, this study proposes a copper-delivery-free strategy for cuproptosis enhancement and provides a promising nanomedicine paradigm for sensitized therapy of EC.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"3 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A bioelectronic nanopillar patch for drug-free antibacterial eradication and oxidative stress-regulated wound repair 一种用于无药物抗菌根除和氧化应激调节伤口修复的生物电子纳米柱贴片

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183089

Jiayi Hou, Jie Gao, Shangdongze Wu, Yutong Bai, Haixu Dou, Lingjie Song, Yong Fan, Weihua Ming, Hoon Eui Jeong, Jie Zhao, Luquan Ren

{"title":"A bioelectronic nanopillar patch for drug-free antibacterial eradication and oxidative stress-regulated wound repair","authors":"Jiayi Hou, Jie Gao, Shangdongze Wu, Yutong Bai, Haixu Dou, Lingjie Song, Yong Fan, Weihua Ming, Hoon Eui Jeong, Jie Zhao, Luquan Ren","doi":"10.1016/j.cej.2026.183089","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183089","url":null,"abstract":"The escalating antimicrobial resistance crisis necessitates drug-free strategies, yet nature-inspired nanopillar arrays exhibit limited efficacy (≤55%) against Gram-positive pathogens. Herein, we present a flexible bioelectronic patch (ES-NP) that achieves broad-spectrum bactericidal efficacy by synergistically coupling electrical stimulation (ES) with nanostructured mechanical disruption. The ES-NP comprises polypyrrole/polylactic acid nanopillar arrays (Ppy/PLA NP) integrated with a wire-free microampere circuit, maintaining stable conductivity under deformation. Applying ultra-low ES (~20 μA cm<ce:sup loc=\"post\">−2</ce:sup>) dynamically modulates the biointerface, shifting Zeta potential and altering wettability to facilitate charge transfer. Crucially, the ES-NP exhibits a cell-type-selective dual-modulatory effect on reactive oxygen species (ROS): it significantly elevates intracellular ROS in bacteria, contributing to synergistic mechano-electrical antibacterial activity, while reducing ROS accumulation and restoring redox homeostasis in mammalian cells to attenuate inflammation. Consequently, the ES-NP achieves potent <ce:italic>in vitro</ce:italic> activity against <ce:italic>E. coli</ce:italic> (100%), <ce:italic>S. aureus</ce:italic> (98.22%), and MRSA (99.18%), substantially outperforming standalone nanopillar arrays. In a murine model, the ES-NP suppressed infection-induced inflammation and accelerated tissue regeneration, achieving collagen deposition-a 7.5-fold increase over controls. By integrating electrically tunable biointerfacial properties with cell-type-selective oxidative stress regulation, this drug-free platform offers a powerful solution for combating recalcitrant infections and promoting wound healing.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"26 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the synergy of piezoelectric polarization and oxygen vacancies in Y-doped SrTiO3 for enhanced N2 photofixation 揭示了y掺杂SrTiO3中压电极化和氧空位对增强N2光固定的协同作用

IF 15.1 1区工程技术

Chemical Engineering Journal Pub Date : 2026-10-13 DOI: 10.1016/j.cej.2026.183082

Jinyu Liu, Nan Zheng, Xiaoli Dong, Yubo Zhang, Xinyue Liu

{"title":"Unveiling the synergy of piezoelectric polarization and oxygen vacancies in Y-doped SrTiO3 for enhanced N2 photofixation","authors":"Jinyu Liu, Nan Zheng, Xiaoli Dong, Yubo Zhang, Xinyue Liu","doi":"10.1016/j.cej.2026.183082","DOIUrl":"https://doi.org/10.1016/j.cej.2026.183082","url":null,"abstract":"Piezoelectric-assisted photocatalysis offers a sustainable route for N<ce:inf loc=\"post\">2</ce:inf> fixation, but is often hampered by weak piezoelectric polarization and insufficient N<ce:inf loc=\"post\">2</ce:inf> chemisorption/activation sites. Herein, we introduced aliovalent Y-doping into SrTiO<ce:inf loc=\"post\">3</ce:inf> to induce lattice distortion for enhanced piezoelectric response and generated abundant oxygen vacancies for N<ce:inf loc=\"post\">2</ce:inf> chemisorption. The optimized 3%Y-STO achieves a remarkable NH<ce:inf loc=\"post\">3</ce:inf> yield of 642.66 μmol·g<ce:sup loc=\"post\">−1</ce:sup>·h<ce:sup loc=\"post\">−1</ce:sup> under dual piezocatalytic and visible-light (PE/Vis) excitation. PFM measurements confirm the significantly improved piezoelectricity, and the resulting polarization field drives efficient carrier separation. DFT calculations reveal that Y-induced oxygen vacancies serve as active sites for N<ce:inf loc=\"post\">2</ce:inf> adsorption, while the piezoelectric polarization facilitates the activation of adsorbed N<ce:inf loc=\"post\">2</ce:inf>. This synergy between piezo-driven charge separation and defect-mediated N<ce:inf loc=\"post\">2</ce:inf> activation enables efficient N<ce:inf loc=\"post\">2</ce:inf> reduction. This work validates aliovalent doping as an effective dual-function strategy for sustainable piezophotocatalytic N<ce:inf loc=\"post\">2</ce:inf> fixation.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"16 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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