Chemical Engineering Journal最新文献

{"title":"Mn and S-doped nickel molybdate/nickel molybdate hydrate micro-structures for supercapacitor applications","authors":"Ahmed H. Al-Naggar, Vijaykumar V. Jadhav, Shoyebmohamad F. Shaikh, Balaji G. Ghule, Rajaram S. Mane","doi":"10.1016/j.cej.2025.163085","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163085","url":null,"abstract":"Scientific community<!-- --> <!-- -->is still attempting to understand the synergistic interaction between heteroatom doping and the design of rational heterostructured metal oxides. This is a significant and efficient method for constructing high-capacity electrochemical energy storage systems. In the present work, manganese (Mn) and sulfur (S) are co-doped precisely into nickel molybdate and nickel molybdate-hydrate (Mn-S-NiMoO₄/NiMoO₄⋅xH₂O@NF denoted as Mn-S-NMO) using a novel chemical approach for ameliorating the charge storage kinetics. The Mn-S-NMO electrode demonstrated a higher specific capacitance of 10758.75F g⁻¹ at 6 A g⁻¹ compared to undoped NMO (2280F g⁻¹ at 6 A g⁻¹) electrode, which is one of the highest reported values for metal oxides to date. This remarkable performance is attributed to its unique crystal structure, the collaboration of dual-ion dopants, interfacial synergistic modifications, the presence of multi-valent ions, defined oxygen vacancies, improved conductivity, increased active sites, rapid ion diffusion and electron transfer, superior higher specific capacitance, charge-transfer efficiency, and reliable cycling stability. Moreover, a symmetric supercapacitor having Mn-S-NMO//Mn-S-NMO configuration achieves an energy/power density of 52.4 Wh kg⁻¹//2100 W kg⁻¹ also demonstrates durable redox cycle life with 88.7 % even after 20000 redox cycles attempted at an excessive current density of 15 Ag⁻¹. The as-obtained symmetric supercapacitor, with two devices in series, has successfully powered a “<em>CNED</em>” colorful panel with 42 LEDs at full brightness for 10 min, demonstrating, by synergistic modulating, the practical significance and scientific merits of the heteroatom-doped hydrated nickel molybdate electrode for real-world commercial appliances.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"33 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143876228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closed-loop recycling for poly(ethylene terephthalate) (PET) plastic: depolymerization, monomer separation, and recycled PET (rPET)","authors":"Taishun Yang, Qingming Fan, Hao He, Chuang Gao, Zixu Yang, Jing Xu","doi":"10.1016/j.cej.2025.163038","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163038","url":null,"abstract":"Closed-loop chemical recycling offers a promising solution to the end-of-life challenges of plastic waste. However, efficiently cleaving bonds to generate value-added products and develop chemically recyclable polymers remains a considerable challenge. We have developed a closed-loop upcycling strategy that depolymerizes poly(ethylene terephthalate) (PET) into bis(2-hydroxyethyl) terephthalate (BHET), followed by polycondensation to produce recycled PET (rPET). A series of xMn/Zn (x = 0, 0.5, 1, 2) catalysts, where x represents the molar ratio of Mn and Zn, were synthesized and employed to depolymerize PET plastic into the BHET monomer. The efficient PET glycolysis approach, utilizing the high surface area and weak acid sites of the 1Mn/Zn catalyst, achieved complete depolymerization of PET plastic with a BHET yield of 93.6 %. The recovered monomers can be utilized to remanufacture rPET, which exhibits competitive molecular weight, thermal stability, and rheological properties. The energy efficiency and techno-economic feasibility of the strategy for recycling PET waste plastic were assessed by constructing a lab-scale 5.0 g-grade process and simulating a 1-ton-grade process. This work introduces a closed-loop “PET-BHET-rPET” process, addressing end-of-use challenges, offering a cost-effective method, and providing a sustainable solution for upcycling plastic waste.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"7 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143876234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bio-entrapment of Chlorella vulgaris mimicking granular sludge: Insights into aggregated microalgae growth and symbiotic bacteria under antibiotic stress","authors":"Xiaolei Liu, Xiaoman Jiang, Anjie Li","doi":"10.1016/j.cej.2025.163075","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163075","url":null,"abstract":"Microalgal-bacterial granular sludge (MBGS) offers an efficient solution for low-carbon sewage treatment by eliminating challenging sludge-water separation processes. However, the impact of extracellular polymeric substances (EPS)-enveloped micro-environments on microalgae and the role of microalgae-derived phytohormones in bacterial signaling in MBGS remain poorly understood. This study investigated the characteristics of <em>Chlorella vulgaris</em> within an EPS-enveloped micro-environment using bio-entrapment in natural polysaccharide-protein (PS-PN) hydrogel granules. Results showed that PS-PN hydrogel bio-entrapment facilitates microalgal cell aggregation and proliferation, and upregulated pathways for photosynthesis, carbon metabolism, and antioxidant defense, suggesting that aggregated growth in PS-PN granules enhanced carbon fixation, organic metabolism, and environmental adaptation. In addition, tryptophan in the hydrogel activated the tryptamine pathway of <em>C. vulgaris</em>, increasing indoleacetic acid (IAA) production to 212.88 ± 7.86 μg/L (vs. 1.95 ± 0.10 μg/L in suspended cells). This IAA alleviated<!-- --> <em>Pseudomonas stutzeri</em> <!-- -->growth inhibition under sulfamethoxazole (SMX) stress. The microalgae-bacteria symbiotic system seeded with aggregated-growth microalgae exhibited superior growth and antioxidant enzyme activity under SMX stress. This study highlights the advantages of aggregated-growth microalgae in supporting both their survival and that of symbiotic bacteria under antibiotic stress, and provides new insights into the role of microalgae-derived phytohormones in microalgae-bacteria signaling and stress resistance within MBGS.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"7 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143876201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathways to green/blue methanol: exploring 16 different approaches incorporating electrolyzer, Allam cycle, and steam methane reforming","authors":"Taehyun Kim, Yungeon Kim, Jinwoo Park","doi":"10.1016/j.cej.2025.162995","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162995","url":null,"abstract":"Efforts to reduce greenhouse gas emissions necessitate a decrease in natural gas consumption. This also applies to grid electricity and blue H₂, both of which are major energy sources derived from natural gas. This study explores the strategic use of natural gas—specifically through grid electricity sales and blue H₂ production—to ensure economic feasibility in the transition to green methanol, which offers potential for CO₂ storage and utilization. Two primary oxy-fuel combustion-based approaches are investigated to reduce the levelized cost of methanol (LCOM): (i) power generation via the Allam cycle and (ii) blue methanol production through steam methane reforming. Each of these methods is combined with five different types of electrolyzers, resulting in 16 distinct production pathways. Energy efficiency, carbon efficiency, and economic feasibility—including carbon tax considerations—are analyzed and compared across these pathways. Additionally, the sustainability of the process is assessed based on LCOM results, incorporating economic data from six countries as well as projected technological advancements. The electrolyzer achieves a high efficiency of over 60 % when integrated with SMR. However, in terms of specific carbon emissions, the Allam achieves below −1.0 tCO₂/tMeOH. The integration of the Allam cycle with an H₂O/CO₂ co-electrolyzer demonstrates the highest potential across various scenarios. The findings of this study provide new insights and benchmarks for leveraging natural gas in the transition to green methanol. Notably, reducing LCOM through grid electricity sales presents an alternative pathway for green methanol production without dependence on blue hydrogen infrastructure.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"5 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143876261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stable all-solid-state lithium metal batteries enabled by ex-situ stress buffer layer and in-situ ion flow regulator","authors":"Lilin Wu, Yuexin Fang, Laurent Calvez, Qixing Wu, Bo Fan, Xianghua Zhang, Hongli Ma, Bai Xue","doi":"10.1016/j.cej.2025.163068","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163068","url":null,"abstract":"All-solid-state lithium metal batteries (ASSLMBs) hold tremendous potential due to their high energy density and enhanced safety compared with liquid lithium batteries. However, their commercialization is largely hindered by the uncontrollable lithium dendrites, which induce short circuits and poor cycling stability. Lithium dendrite growth can be inhibited through two main approaches: controlling lithium deposition behavior and managing internal stress caused by volume changes. In this work, we designed an artificial interface layer composed of an Ag₂O upper layer and a Li-Ag alloy bottom layer through a solution-based displacement reaction. The Ag₂O layer serves to homogenize the distribution of lithium-ion concentration, thereby enabling uniform lithium deposition. Simultaneously, the Li-Ag alloy solid solution, structured as a porous microdomain formed by nanoparticles, helps buffer the plating-induced stress within bulk lithium. Thanks to the synergistic effect of the Ag₂O and Li-Ag alloy layer, Li symmetric cells achieved a high critical current density of over 1.2 mA cm⁻² at a capacity of 0.2 mA h cm⁻², along with ultra-stable cycling for over 4500 h at 0.2 mA cm⁻². Moreover, ASSLMBs paired with LiFePO₄ cathodes exhibited superior rate capabilities and stable cycling after 250 cycles at 0.5C. Even when paired with Li₂S cathodes, enhanced electrochemical performance was observed after 200 cycles at 0.2C. This study provides an effective strategy for the development of ASSLMBs through the synergistic regulation of lithium deposition and the mitigation of electroplating-induced stress, ultimately suppressing the formation of lithium dendrites.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"73 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced photocatalytic defluorination of perfluorooctanoic acid through integrated hydrogen atoms/electrons reduction and ROS oxidation with metal–organic framework heterogeneous catalysts","authors":"Cai Yan, Zheng Zhong, Jing Wang, Kun Feng, Defeng Xing","doi":"10.1016/j.cej.2025.163058","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163058","url":null,"abstract":"The escalating prevalence of perfluorooctanoic acid (PFOA) abuse and discharge globally poses a substantial threat to human health and aquatic ecosystems. However, the removal of persistent PFOA from water sources remains a challenge. Herein, Fe-BTC/BiOCl, a bifunctional photocatalyst combining iron-based metal–organic framework (MOF) and bismuth oxychloride, was developed that integrated the hydrogen atoms/electrons reduction with reactive oxygen species (ROS) oxidation to facilitate an efficient photocatalytic process aimed at the deep defluorination and mineralization of PFOA. Considering the 3D nanostructures, strong electronic interaction and interlaced energy band structure, a Z-scheme Fe-BTC/BiOCl heterostructure was fabricated to attain efficient carrier separation accompanied by a significant abundance of oxygen vacancies. Under LED-lamp irradiation, the Fe-BTC/BiOCl heterostructure obtained 98.7 % degradation of PFOA within 30 min. Electron paramagnetic resonance analysis and scavenging experiments indicated that the ROS and hydrogen atoms/electrons generated in the Fe-BTC/BiOCl/visible light system were the primary active species responsible for the efficient degradation of PFOA. Furthermore, the quantitative analyses of intermediates and density functional theory calculations revealed that the PFOA degradation process primarily involve the prioritized cleavage of carboxyl group and the subsequent repeated unzipping cycle that included the removal of − CF₂H groups and elimination of fluoride ions due to the cleavage of C–C and C − F bonds, respectively. These findings offer precious insights for designing green and efficient photocatalysts and enhance understanding of the photocatalytic defluorination processes for PFOA.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"7 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defect density of zirconium determines its binding sites and force to antibiotic resistance genes","authors":"Han Ying, Zhang Yuman, Yin Meiqi, Wu Bin, Zhang Qingrui, Wu Hao","doi":"10.1016/j.cej.2025.163042","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163042","url":null,"abstract":"Covalent binding between phosphate and Zirconium (Zr) based nanomaterials (NMs) leads to highly selective adsorption of phosphate, and thus Zr-based NMs may provide ideal adsorbents to control antibiotic resistance genes (ARGs) containing phosphate group. This study investigated the adsorptive interactions of ARGs and Zr-based NMs, i.e., hydrous zirconium oxide (HZO), UiO-66, and defect rich UiO-66 (Dr-UiO-66). Dr-UiO-66 had a higher adsorption rate and capacity (0.87 min⁻¹ and 3.59 mg/g) compared with HZO (0.07 min⁻¹ and 0.43 mg/g), and UiO-66 (0.87 min⁻¹ and 1.67 mg/g). The results demonstrated that defection sites provided more active sites for ARGs adsorption and improved the adsorption performance, which was further proved by various characterization methods. Molecular dynamic simulations revealed that the sorption energy between ARGs and Dr-UiO-66 was lower than that between ARGs and HZO, indicating that the potential covalent binding force may formed between Dr-UiO-66 and ARGs, when each Zr lost one BDC ligand in the molecular cluster. The Dr-UiO-66 exhibited excellent adsorption and selectivity in removing ARGs, even when high concentrations of Cl⁻/NO₃^–/SO₄²⁻ ions were present. Although high concentration PO₄³⁻ (5 mM) significantly hindered the adsorption of ARGs, the ARG removal performance of Dr-UiO-66 is unlikely to be inhibited by PO₄³⁻ in real application scenarios with relatively low PO₄³⁻ (0.1 mg/L). When 0.1 g Dr-UiO-66 was used to treat 200 mL simulated wastewater containing 1 μg/mL <em>tet</em>M gene initially, the concentration of <em>tet</em>M gene in the effluent could be reduced to below detection limit of the qPCR method. The results indicated that the Dr-UiO-66 hold promise as a selective and effective adsorbent for removing ARGs from contaminated waters.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"14 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-step negative isolation and concentration of extracellular vesicles by graphene oxide composite hydrogels","authors":"Qi Yang, Xinxin Liu, Kaiguang Yang, Peng Ge, Bowen Lan, Zhigang Sui, Yu Liang, Guixin Zhang, Hailong Chen, Huiming Yuan, Lihua Zhang","doi":"10.1016/j.cej.2025.163066","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163066","url":null,"abstract":"Extracellular vesicles (EVs) are proven to hold great promise for diverse therapeutic and diagnostic applications. However, large-scale preparation of EVs from bulk liquid samples including culture medium and body fluids is a prerequisite for their clinical translation applications. Herein, we proposed a single-step negative isolation and concentration method using graphene oxide composite hydrogels (hGOs), by which both protein impurities are adsorbed inside the hGOs while EVs with large sizes are excluded from the outside by surface nano-sized channels, meanwhile the end-product was also concentrated by at least 3–5 times. Taking advantage of this method, we isolated the EVs from large-volume rat bronchoalveolar lavage fluids (BALFs). Compared to gold-standard ultracentrifugation, although the isolation purity of EVs was comparable, the recovery of EVs ranging from 81.4 %–85.9 % was greatly achieved by hGOs with excellent reproducibility (RSD = 2.4 %, n = 9), 2 times higher than that obtained via ultracentrifugation. Proteomic analysis of EVs from severe acute pancreatitis-lung injury (SAP-ALI) BALFs identified 25 differentially expressed proteins distinguishing disease and healthy states. Critically, this method enabled scalable production of ginger-derived EVs (10–150 mL extracts), with NTA-confirmed linear yield scalability (R² &gt; 0.98), while functional assays demonstrated their anti-inflammatory efficacy via significant suppression of TNF-α, MIP-2, and NO (P &lt; 0.0001) in macrophage models. We believed that the newly developed hGOs would be a useful tool for achieving highly efficient EV production from bulk liquid samples, facilitating many important biological and clinical applications.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"14 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid and selective E-waste gold extraction from aqua regia by dual redox active-sites of skeleton modulated poly(organo)phosphazenes","authors":"Yasir Abbas, Sajjad Ali, Majid Basharat, H.M. Adeel Sharif, Muhammad Ahsan Iqbal, Mohamed Bououdina, Haoliang Wang, Niaz Ali Khan","doi":"10.1016/j.cej.2025.163037","DOIUrl":"https://doi.org/10.1016/j.cej.2025.163037","url":null,"abstract":"The sustainable recovery of gold from electronic waste (E-waste) remains a significant challenge due to lack of multiple redox active-sites in the existing adsorbents, their high cost, and poor stability in extreme acidic conditions. Herein, we rationally designed the skeleton engineering of poly(organo)phosphazene via substitution reaction of hexachlorocyclotriphosphazene (HCCP) with p-phenylenediamine (DA), 1,4-benzenedithiol (DT), and 4-aminothiophenol (AT), producing poly(p-phenylenediamine-co-cylotriphosphazene) (PDA) with N-redox active-sites, poly(1,4-benzenedithiol-co-cylotriphosphazene) (PDT) containing S-redox active-sites, and poly(4-aminothiophenol-co-cylotriphosphazene) (PAT) holding dual N-S-redox active-sites. The PDA, PDT, and PAT in the N-bromosuccinimide/pyridine (NBS/Py) leaching solution demonstrated extraction efficiency of 83.7 % Au³⁺, 45.5 % Cu^2+, 44 % Ni²⁺, and 83.6 % Au³⁺, 47.4 % Cu²⁺, 48 % Ni²⁺, and 83.1 % Au³⁺, 48.5 % Cu²⁺, 48.8 % Ni²⁺. While, in the aqua regia, these adsorbents showed extraction efficiency of 70.0 % Au³⁺, 14.0 % Cu²⁺, 13.8 % Ni²⁺, and 92.3 % Au³⁺, 6.4 % Cu²⁺, 9.8 % Ni²⁺, and 95.6 % Au³⁺, 13.0 % Cu²⁺, 10.3 % Ni²⁺. In particular, the PAT with the dual N-S-redox active sites achieved maximal Au³⁺ extraction efficiency (99.2 %), which is 1.05 and 1.04 times higher than PDA and PDT within 15 min, superb uptakes of 2000 mg/g, excellent selectivity (99.9 %) in a mixture of eight metal ions (Al, Co, Cu, K, Mg, Na, Ni, Mn), 100 % removal capacity and high stability even in pure aqua regia leaching solution. Gold ions adsorbed on these adsorbents, spontaneously reduced, experienced nucleation, and grew into single crystalline nanoplates along (111) planes as well as nanolayers composed of Au-single-atoms and Au-nanoclusters. The density function theory (DFT) calculations and variation in binding energies of N and S indicated that due to the synergy of dual N-S-redox active-sites, the PAT showed enhanced performances and excellent selectivity. For commercial applications, the as-synthesized PDA, PDT, and PAT were highly stable in pure aqua regia leaching solution, showing precisely selective and rapid gold extraction (70 %, 92 %, 96 %, respectively) than N- NBS/Py leaching systems (83 %) with traces of other competing metals. This study proves that skeleton-modulated poly(organo)phosphazene greatly facilitates gold extraction for industrial-scale applications.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"1 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lophatherum-Gracile driven near-infrared carbon dots inhibit ferroptosis and mitophagy to treat acute kidney injury","authors":"Lijuan Yang, Fan Dai, Haitian Tang, Man Li, Yibo An, Yubo Tan, Renyuan Liu, Xinyu Tan, Wenxiang Zhang, Syed Faheem Askari Rizvi, Junjie Zou, Zhixiang Lu, Gang Liu","doi":"10.1016/j.cej.2025.162637","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162637","url":null,"abstract":"Carbon dots (CDs) based-biomass are known for their excellent safety but often face challenges such as short emission (Em) wavelength and low quantum yield (QY). Here, using the traditional Chinese medicinal lophatherum gracile as a carbon source, we combined conventional decoction techniques with CDs preparation methods to obtain safe and green CDs (Lophatherum-Gracile driven near-infrared carbon dots, L-CDs) for the first time with an Em peak at 666 nm, a shoulder peak at 730 nm, and a QY of 13.36 %. L-CDs showed remarkable stability, safety, and resistance to photobleaching. Notably, it effectively quenched reactive oxygen species (ROS) and exhibited specific sensitivity to Fe(II). Additionally, L-CDs exhibited potential in treating ferroptosis-related inflammation and inhibiting mitophagy, and they were found to be effective in preventing and treating cisplatin (CDDP)-induced acute kidney injury (AKI). These effects were comparable to those of commercially available ferroptosis therapies-Ferrostatin-1 (Fer-1) and deferoxamine (DFO). Overall, our work presents novel, safe, and eco-friendly near-infrared L-CDs that can be effectively utilized for identifying cellular organelle and <em>in vivo</em> imaging, as well as for treating ferroptosis, mitochondrial-related inflammation, and chemotherapy-induced AKI. These findings broaden the potential applications of CDs in biomedical diagnosis and therapy, intending to advance clinical development.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"127 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}