Chemical Engineering Journal最新文献

{"title":"Vibration-enhanced RF-biased inductively coupled plasma fluidized bed for depositing diamond-like carbon on powders","authors":"Zhijun Ai, Zhicheng Wu, Qingzhe Zhu, Zhengjie An, Le Feng, Qiaogen Zhang","doi":"10.1016/j.cej.2025.162235","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162235","url":null,"abstract":"Diamond-like carbon (DLC) is extremely attractive for improving the surface properties of powder materials. However, DLC deposition on powders remains a major challenge due to stringent plasma conditions required and difficulties of effectively processing it with plasma, severely hindering this application. This study proposed an RF-biased inductively coupled plasma (ICP) fluidized bed reactor to address this challenge, especially introducing vibration to render it suitable for cohesive fine powders. The reactor generated high-density plasma using inductive coupling and controlled local ion energy using RF bias, thereby forming a high-flux and high-energy ion region, where powders were fluidized by both gas flow and vibration for DLC deposition. Taking alumina powders as an example, it was experimentally demonstrated that the reactor could uniformly deposit DLC on powders with particle sizes ranging from 120 to 10 µm within 10 min, thereby enhancing their hydrophobicity. The proposed reactor laid a foundation for the application of DLC on powder materials.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"38 6 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"π-Conjugated molecule-based self-assembled monolayers enable high-efficiency pure-blue perovskite LEDs","authors":"Hyo Jae Lee, Jae Woong Jung","doi":"10.1016/j.cej.2025.162261","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162261","url":null,"abstract":"The hole-injecting interface is crucial for achieving high optoelectronic performance of perovskite light-emitting diodes (PeLEDs), as it lowers the energy barrier between the anode and perovskite emitting layers (EMLs), facilitates efficient hole-carrier extraction, suppresses recombination, and supports growth of highly crystalline perovskite EMLs. However, the widely used hole injection layer (HIL), poly(3,4-ethylenedioxythiophene):polystyrene sulfonic acid (PEDOT:PSS), has inherent limitations such as low work function, high acidity, and susceptibility to corrosion, the self-assembled monolayers (SAMs) with functional groups have emerged as promising alternatives to PEDOT:PSS for hole-injecting interfaces. In this study, 4PADCB, a phosphonic acid-based SAM with extended π-conjugation, is applied to prepare high-performance pure blue PeLEDs. The 4PADCB provides robust interfacial properties including excellent electrical and morphological characteristics by close interaction with perovskite lattices, demonstrating pure-blue electroluminescence of PeLEDs at 472 nm with a low turn-on voltage (3.20 V) and a peak external quantum efficiency (EQE) of 4.26 %, a fourfold improvement over PEDOT:PSS-based control devices. This enhancement is attributed to reduced interfacial defects and improved carrier injection balance, leading to efficient radiative recombination kinetics. These results highlight the potential of highly conjugated SAMs as innovative components for hole-injecting interfaces, enabling significant advances in PeLED efficiency and stability.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"19 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging strategies to engineer decellularized extracellular matrix in wound treatment","authors":"Wen Xue, Xinyue Sun, Yuxuan Xia, Xiping Jiang, Bin Duan, Xuanyong Liu","doi":"10.1016/j.cej.2025.162270","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162270","url":null,"abstract":"Decellularized extracellular matrix (dECM), consisting of tissue-derived bio-functional molecules, plays crucial roles in next-generation regenerative medicine and has shown extensive feasibility toward wound treatment. Despite the effectiveness, dECM is imposing additional restrictions in treating complicated wounds, mainly due to its poor processibility for practical applications, mechanical and biochemical mismatch with the ideal wound treatment constructs. Besides, the complex components in dECM and their cell modulation mechanisms are not clear and waiting to be unveiled. Thus, a profound understanding of the challenges with which the dECM are confronted, as well as the available strategies to meet these challenges, is essential to spur the optimization of future dECM and enhance its clinical performance. Motivated thus, this review is at the goal of revealing the trend of dECM in wound treatment, raising key challenges that limits its development, and summarizing the available strategies to address these issues. Here, four engineering strategies including processibility engineering, microenvironment targeting functionalization, and immunomodulation engineering of dECM were proposed. Overall, this review emphasizes issues and provides additional insight in advanced strategies for pushing dECM toward wound treatment and even regenerative medicine.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"71 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double-emulsion droplet digital CRISPR/Cas12a for amplification-free, absolute quantification of nucleic acids at attomole levels","authors":"Yang Zhang, Hangrui Liu, Shi-Yang Tang, Yaxiaer Yalikun, Tracie J. Barber, Keisuke Goda, Ming Li","doi":"10.1016/j.cej.2025.162098","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162098","url":null,"abstract":"The quantification of nucleic acids is of prominent importance for biology and medicine sciences. Droplet digital polymerase chain reaction (ddPCR) provides an absolute measure of target nucleic acid molecules with unrivalled sensitivity and accuracy, but suffers from limitations inherent to PCR amplification, droplet partition, and signal detection. Here, we present an ultrasensitive, rapid, and high-throughput technique for the absolute quantification of nucleic acids without the need for amplification, by combining the <u>d</u>ouble-emulsion (DE) <u>d</u>roplet <u>d</u>igital platform with <u>CRISPR</u>/Cas12a system (d³CRISPR). We demonstrate the developed approach by accurately quantifying various DNA molecules, such as target human papillomavirus (HPV) 18, HPV16, and <em>E. coli</em> DNA, at concentrations down to attomole levels. This represents an over 1,000-fold improvement in the limit of detection (LOD) compared to existing bulk analysis amplification-free Cas12a assays. Given the versatility and generality of the CRISPR system, we believe that this approach has great potential in the detection and measurements of diverse nucleic acid molecules for many biomedical, clinical, and environmental applications.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"183 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organic molecule-based nanoparticles for multimodal colorectal cancer therapy: Oxidative stress-induced apoptosis and ferroptosis","authors":"Dezhou Peng, Zhibo Zhang, Qiyu Zhang, Yichao Liu, Ning Wang","doi":"10.1016/j.cej.2025.162259","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162259","url":null,"abstract":"The combination of chemotherapy (CT), chemodynamic therapy (CDT), and sonodynamic therapy (SDT) to disrupt redox homeostasis in tumor cells, thereby inducing apoptosis and ferroptosis, represents a promising therapeutic strategy for combating colorectal cancer (CRC). However, many existing multimodal nanoparticles are inorganic nanoparticles, non-biodegradable nature, lack active targeting capabilities and fail to effectively consume intracellular glutathione (GSH), which somewhat compromises their clinical potential. In this study, we developed an organic molecule-based nanoparticle, cRGDFc@Ce6, which features active targeting, GSH consumption, and CT/SDT/CDT functionalities. The morphology of cRGDFc@Ce6 was spheroidal, with an average particle size of approximately 172 ± 1.9 nm, and demonstrated good stability and active targeting capabilities. cRGDFc@Ce6 enters CRC cells and is selectively activated by the abundant GSH within these cells, leading to GSH consumption and the subsequent degradation of cRGDFc@Ce6, which releases the drug camptothecin (CPT). Upon ultrasound application, cRGDFc@Ce6 initiates a domino-like cascade amplification of oxidative stress, disrupting the redox homeostasis of cancer cells. <em>In vivo</em> experiments demonstrated that cRGDFc@Ce6 achieves an inhibition rate of up to 86.4 ± 5.1 % against CRC while exhibiting good biosafety. The GSH levels in mice serum from the cRGDFc@Ce6 + US group was significantly reduced, measuring approximately 0.42 times those in the control group. Furthermore, Western blotting, RNA sequencing, and immunofluorescence, confirmed that cRGDFc@Ce6 + US induces tumor cell apoptosis and ferroptosis. Overall, our findings provide a novel strategy for the combined treatment of CRC utilizing CT, CDT, and SDT, offering significant insights for the advancement of innovative and precise nanomedicine.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"59 27 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-channels engineering of carbon tube/NiCo-LDH composites for enhanced ion diffusion and electron transfer","authors":"Qiuhong Bai, Xiaoyan Wang, Yu Zhang, Yan Wang, Cong Li, Yang Wang, Xiaoheng He, Yehua Shen, Hiroshi Uyama","doi":"10.1016/j.cej.2025.162094","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162094","url":null,"abstract":"Dual-Phase engineering for enhanced ion diffusion and electron transfer by structural design and electronic modulation is an effective strategy to construct high-performance electrode materials. In this paper, biomass-based carbon tube/Ni-Co bimetallic hydroxide (CT/NiCo-LDH) composite was synthesized using biomass carbon tube as substrate, and NiCo-LDH composed of thin nanosheets is grown on the surface of the carbon tube. The carbon tube not only has a large specific surface area, but is rich in oxygen-containing functional groups, which is conducive to NiCo-LDH loading and nucleation. The nanoflower-like hierarchical structure enlarged ions intercalating channels, which is conducive to energy storage. The Ni-doping and combination of high specific capacity of NiCo-LDH and high electrical conductivity of carbon materials cooperatively improved the electrochemical kinetics and cycling stability as fast ion/electron dual pathways. The electrochemical performances are further suggested by density functional theory calculations and capacitance contribution fitting, which provides theoretical assistance for the excellent reaction kinetics. The specific capacity of the composite electrode was 1927 F g⁻¹ at 0.5 A g⁻¹, and possessed excellent capacitance retention rate of 82 % at 20 A g⁻¹. The asymmetric supercapacitor fabricated using CT/NiCo-LDH positive electrode and biomass carbon negative electrode displayed a high energy density of 90.4 W h kg⁻¹. The current research provides a new idea for the design of fast ion/electron dual pathways electrodes and high energy density supercapacitors.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"73 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermoelectric performance in Ag2Se nanocomposites: The role of interstitial Ag and Pb orbital hybridization","authors":"Khak Ho Lim, Yuxuan Xia, Lixiang Xu, Mingjun Zhao, Mingquan Li, Ye Cheng, Jiale Mao, Shuang Wang, Lei Chen, Sai Wing Tsang, Pingwei Liu, Qingyue Wang, Xuan Yang, Wen-Jun Wang, Andreu Cabot, Min Hong, Yu Zhang, Yu Liu","doi":"10.1016/j.cej.2025.162265","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162265","url":null,"abstract":"Ag₂Se has emerged as a promising thermoelectric (TE) material for room-temperature applications. However, its TE performance is limited by the low carrier effective mass (<em>m*</em>) of only 0.1 <em>m₀</em>, where <em>m₀</em> represents the free electron mass. In this study, we employ a microwave-assisted method to synthesize nanostructured Ag_2-xSe with Pb doping that is found to increase <em>m*</em> to 0.4 <em>m₀</em>. Accordingly, Seebeck coefficient is significantly enhanced, which together with the maintained high electrical conductivity, leads to enhanced electronic transport. The increase in <em>m*</em> is systematically investigated by density functional theory calculations and linked to the enhanced electronic by modeling simulations. The calculated band structures reveal that the hybridization of heavy Pb-6p orbitals flattens the conduction band edges, and thereby enhances <em>m*</em>. Furthermore, Pb doping significantly reduces lattice thermal conductivity due to the high-density point defects, dislocations, and grain boundaries, as revealed by detailed electron microscopy characterizations. The synergy from both enhanced electronic transport and reduced phonon propagation yielded a maximum figure of merit of 1.04 at 376 K, and an average figure of merit of 1.0 for Pb-doped Ag_1.9Se. The optimized TE performance is further validated in a flexible TE generator, which produced a maximum output power of 0.6 μW at a temperature difference of 45 K. These findings demonstrate that enhancing <em>m*</em> and increasing phonon-scattering using vacancy tuning and aliovalent doping effectively boosts the TE performance of Ag₂Se, a strategy that can be extended to other TE materials to maximize their potentials for power generation and thermoelectric cooling applications.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"32 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase engineering Governing reaction pathways in Phosphorus-Doped copper oxide for selective CO2 electroreduction to CH4 and Multicarbon products","authors":"Haiyan Lu, Hu Zang, Changjiang Liu, Xin Liu, Wenli Xu, Nan Yu, Baoyou Geng","doi":"10.1016/j.cej.2025.162269","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162269","url":null,"abstract":"Copper-based catalysts exhibit moderate adsorption energy for *CO intermediates and have attracted significant attention for CO₂ electroreduction to fuels and high-value chemicals, but their low activity and poor selectivity remain challenges. Herein, we synthesized phosphorus-doped copper oxide (CuO_xP_y) and demonstrated that phosphorus governs the phase transition, creating distinct interfaces that regulate proton donors or local OH^– concentrations, thereby modulating the reaction pathway and directing CO₂ electroreduction selectively towards CH₄ or multi-carbon (C₂₊) products. Notably, the P-Cu₂O/Cu interface derived from amorphous CuO_xP_y exhibits a Faradaic efficiency (FE) for CH₄ of 53 % ± 4.99 % at a current density of 0.4 A cm⁻². In contrast, the Cu₂P₂O₇/Cu₂O interface obtained from crystalline CuO_xP_y achieves a FE_C2+ of 74.3 % ± 1.75 % at 0.8 A cm⁻². Experiments and theoretical calculations reveal that the accumulation of proton donors at the P-Cu₂O/Cu interface facilitates the protonation of the *CO intermediate, thereby enhancing CH₄ production. The Lewis acid sites of Cu²⁺ at the Cu₂P₂O₇/Cu₂O interface enhance the local OH^– concentration and lower the energy barrier for C-C coupling, resulting in high selectivity towards C₂₊ products. This study presents a novel paradigm for the rational regulation of selectivity in CO₂ electroreduction products through modulation of the interfacial microenvironment.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"32 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143758057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-level technologies for exploring nanoplastics to amplify cadmium immunotoxicity: Endpoint identification and kinetic model construction","authors":"Xiangxiang Li, Jinhu Wang, Mingyang Jing, Shaoyang Hu, Wansong Zong, Rutao Liu","doi":"10.1016/j.cej.2025.162087","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162087","url":null,"abstract":"Nanoplastics (NPs) that have received global attention can change the environmental behavior and bioavailability of pollutants. Particularly worrisome is that although the spleen is known to be the primary target organ for NPs accumulation and the largest immune organ, it remains unclear whether and how NPs affect the immunotoxicity of pollutants. In this study, cadmium (Cd) was selected as a representative environmental pollutant, and explored the effect and mechanisms of NPs on Cd²⁺-induced immunotoxicity of mouse splenocytes. Results indicated that NPs@Cd²⁺ induced 14.43 % more splenocytes death and more significant inhibition of T and B lymphocyte proliferation than Cd²⁺. Mechanistically, splenocytes under NPs@Cd²⁺ stress experienced more severe mitochondrial damage and accumulation of caspase-3, ultimately inducing 21.32 % of cell apoptosis (Cd²⁺: 16.71 %). Moreover, excessive processing of caspase-1 induced cell membrane perforation, and release of IL-1β and IL-6. Thus, the mitochondria-mediated caspase-3-dependent apoptosis and caspase-1-dependent pyroptosis pathway were identified as the key mechanisms leading to the amplified immunotoxicity. At the molecular level, more significant lysozyme backbone loosening, unwinding and fluorescence sensitization were induced by NPs@Cd²⁺. Molecular docking and dynamics show that Cd²⁺ is most easily bound to the surface of lysozyme, far away from the active site cavity. The more serious structural changes induced by NPs@Cd²⁺ under “protein corona” binding mode are the mechanisms for more significant lysozyme inactivation. This study clarifies for the first time the impact and mechanisms of NPs on the immunotoxicity of Cd²⁺, providing key data and strategies for accurate assessment of the environmental behavior and health risks of NPs. More meaningfully, this work contributes to local governments and municipalities controlling source emissions and reducing immunity-related disease burden by determining the hazardous properties of NPs.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"32 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reshaping bacterial microenvironments: Hybrid biomimetic membrane-coated copper nanosystems combat bacterial biofilm infections by inhibiting bacterial quorum sensing systems","authors":"Liqiang Wang, Qianyu Cai, Yonglan Yang, Qiongmei Mai, Yuezhao Zhou, Yujia Liu, Yanan Liu, Jie Liu","doi":"10.1016/j.cej.2025.162088","DOIUrl":"https://doi.org/10.1016/j.cej.2025.162088","url":null,"abstract":"Quorum sensing inhibitors (QSI) are considered an effective strategy for eradicating bacterial biofilm infections. However, conventional QSI need to be combined with antimicrobials for effective treatment of biofilm infections. Here, we developed a red blood cell membrane and platelet membrane coated copper nanosystem (mCu@CaO₂) with quorum-sensing inhibition and broad-spectrum bactericidal effects. Initially, mCu@CaO₂ targets bacteria, utilizes and improves bacterial microenvironment, reduces bacterial glutathione level, releases highly toxic •OH, destroys bacterial cell membrane and cell wall integrity, and kills <em>MRSA</em>, <em>E.coli</em>, and <em>PAO1</em>. Subsequently, mCu@CaO₂ inhibited <em>MRSA</em> agr ABC system and <em>PAO1</em> PQS, Rhl and Las quorum sensing system, reduced the secretion of various toxins, and inhibited biofilm production and transfer. Finally, in mice models of pulmonary infection and peritonitis, mCu@CaO₂ showed excellent antibacterial effect <em>in vivo</em>, promoting the recovery of bacterial infection and reducing the production of inflammatory factors. In short, this work provides a certain idea for inhibiting bacterial quorum sensing and curing biofilm infection.","PeriodicalId":270,"journal":{"name":"Chemical Engineering Journal","volume":"76 1","pages":""},"PeriodicalIF":15.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}