{"title":"Micro CT-based validation of iron concentration for MPI tracers","authors":"C. Debbeler, J. Muller, K. Ludtke-Buzug","doi":"10.1109/IWMPI.2013.6528337","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528337","url":null,"abstract":"With this simple strategy we are able to proof that the measured mean grey values increase directly proportional with the iron oxide concentration of the ferrofluid. This promises an appropriate determination of the iron oxide concentration based on μCT for evaluation of new tracer materials for MPI.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133133084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic nanoparticles temperature measurements","authors":"I. Perreard, D. Reeves, X. Zhang, J. Weaver","doi":"10.1109/IWMPI.2013.6528341","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528341","url":null,"abstract":"Magnetic nanoparticles (MNPs) have an ever increasing role in the medical world, particularly in thermal therapies (magnetohypertermia, ablation) for the treatment of cancer. These treatments would benefit of accurate monitoring of the temperature of the MNPs for optimal remedial conditions. It has been shown that the magnetic spectroscopy of nanoparticle Brownian motion (MSB), can be used to measure the temperature of MNPs.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127532730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A 3D MPI system for biological studies on MICE","authors":"C. Kuhlmann, T. Wawrzik, F. Ludwig, M. Schilling","doi":"10.1109/IWMPI.2013.6528373","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528373","url":null,"abstract":"By imaging plastic or bio-compatible phantoms, we were studying the properties of the MPI system function and its dependence on components of the imaging system and particle dynamics. In progress towards three-dimensional imaging, depicts a two-dimensional image of an “E” phantom obtained with the scanner, applying the hybrid-matrix approach.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128906658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Separation of Ferucarbotran: A leading candidate of MPI tracer for practical use","authors":"S. Nohara, I. Kato, Y. Ito, T. Honma, Y. Ishihara","doi":"10.1109/IWMPI.2013.6528339","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528339","url":null,"abstract":"It is well known that the possibility of use of Resovist® as a tracer for MPI has been studied, but whose performance using a practicable MPI device is not adequate. In this situation, it has been suggested that the fractionation of Resovist® shows good performance than Resovist® itself1,2,3). Meito Sangyo has been manufacturing Ferucarbotran, an active pharmaceutical ingredients (API) for Resovist®, since 2001, and are studying to obtain a practicable MPI tracer by separation of Ferucarbotran. Here, we report the physical properties such as MPI signal, particle size, T2 relaxivity and the biological behavior of the fractions from Ferucarbotran.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121553793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploiting the symmetry of the magnetic particle imaging system matrix","authors":"A. Weber, T. Knopp","doi":"10.1109/IWMPI.2013.6528329","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528329","url":null,"abstract":"In this work, the first study on the symmetry of the 2D magnetic particle imaging (MPI) system matrix is performed. The matrix symmetries are formed by the symmetries of the drive-field sequence and the characteristic of the Fourier transformation. The symmetries can be exploited for reducing the number of calibration scans that are necessary to acquire the system matrix, which is a time demanding task in MPI. Experiments show that by using vertical and horizontal mirroring of the system matrix, the calibration scan can be accelerated by a factor of four without loss of image quality.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122345519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Franke, U. Heinen, V. Niemann, M. Heidenreich, T. Buzug
{"title":"Alternative hybrid MPI-MRI imaging system design: Superconductive field generator topology","authors":"J. Franke, U. Heinen, V. Niemann, M. Heidenreich, T. Buzug","doi":"10.1109/IWMPI.2013.6528367","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528367","url":null,"abstract":"It was shown that a hybrid MPI-MRI MFG can be realized as superconductive topology which renders the possibility of acquiring sequentially high resolution MPI and high quality MRI data with versatile soft tissue contrast of mice and rats in a single device. Furthermore, depending on the technically feasible and biologically tolerable drive field strength and/or desired field of view, the superconductive MFG can be realized in a broad range in terms of the SF gradient strength independently to the magnetic field strength of the MRI region. This can be realized by selecting a dedicated gradient enhancing coil current density. As this MFG topology depicts two separated imaging regions for MPI and MRI, respectively, the subject hast to be transported by a simple translational movement whereas the signal detector of each modality can be located closely to the imaging volume which allows in both modalities high sensitivity receiving coils.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"85 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121015021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Timmermeyer, H. Wojtczyk, W. Tenner, G. Bringout, M. Gruttner, M. Graeser, T. Sattel, A. Halkola, T. Buzug
{"title":"Super-resolution approaches for resolution enhancement in magnetic particle imaging","authors":"A. Timmermeyer, H. Wojtczyk, W. Tenner, G. Bringout, M. Gruttner, M. Graeser, T. Sattel, A. Halkola, T. Buzug","doi":"10.1109/IWMPI.2013.6528360","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528360","url":null,"abstract":"Given a definition of spatial resolution that considers two objects as distinguished if the minimum value of the gap is less than 50% of the value at the object position [7], both approaches achieved an improvement of the spatial resolution in the 1D simulation study as visualized in Fig. 1 and 2. If the spatial resolution is considered as the minimum width of two distinguished lines, the first approach using spatially shifted images achieved a spatial resolution of 1.7 mm and the second approach using different sampling points achieved a resolution of 2.6 mm. This is an improvement in comparison to the used low resolution images with a spatial resolution of 2 mm (first approach) and 2.9 mm (second approach).","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123869078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The potential of clustered core magnetic particles for MPI","authors":"N. Gehrke, D. Heinke, D. Eberbeck, A. Briel","doi":"10.1109/IWMPI.2013.6528368","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528368","url":null,"abstract":"No obvious differences between the structures of the different particles were found, yet their MPI efficacy varies significantly: the MPS amplitude differs by a factor of up to 6 in the lower and 11 in the higher harmonics between the highest (#1) and lowest (#2) MPI efficacy particles synthesized here. In comparison to Resovist and FeraSpin R this means an improvement by a factor of about three in the lower and two in the higher harmonics in case of the high efficacy particles (#1). Our results from static magnetization measurements allow to quantitatively understand this increase. Such an increase does not represent the theoretical limit, but so far similar performance was only found for size optimized particles obtained from the best state-of-the-art clustered core MPI tracer Resovist and FeraSpin R from aqueous synthesis [2,3] as well as certain mono-crystalline core particles from organic synthesis [4].","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122719066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frequency dependent harmonics generation in iron oxide nanoparticles","authors":"B. Gleich, J. Weizenecker, J. Borgert","doi":"10.1109/IWMPI.2013.6528345","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528345","url":null,"abstract":"We have demonstrated that MPI can work at drive field frequencies much higher than traditionally used frequencies, which has the potential to boost the signal to noise ratio. At such higher frequencies, however, the product of amplitude and frequency can become limiting for continuous operation due to patient heating. In this case, scan durations would have to be limited to maybe several 10 seconds which can still be sufficient for angiographic applications.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131849139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Finas, K. Baumann, L. Sydow, K. Heinrich, K. Grafe, A. Rody, K. Ludtke-Buzug, T. Buzug
{"title":"Superparamagnetic nanoparticles in lymphatic tissue - Detection and distribution in a breast cancer model for magnetic particle imaging","authors":"D. Finas, K. Baumann, L. Sydow, K. Heinrich, K. Grafe, A. Rody, K. Ludtke-Buzug, T. Buzug","doi":"10.1109/IWMPI.2013.6528390","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528390","url":null,"abstract":"The SPIOs are moving from the injection site through the lymph-fat tissue to the axillary region and finally into the axillary lymph nodes. SPIOs follows the traces of lymphatic vessels, respecting the borders and spaces between different tissues. They were found in the neighborhood of collagen fibers and accumulates in distinct regions. We present first results of the approach of SNLB with MPI.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131971321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}