{"title":"分离糖铁:MPI示踪剂的主要候选物","authors":"S. Nohara, I. Kato, Y. Ito, T. Honma, Y. Ishihara","doi":"10.1109/IWMPI.2013.6528339","DOIUrl":null,"url":null,"abstract":"It is well known that the possibility of use of Resovist® as a tracer for MPI has been studied, but whose performance using a practicable MPI device is not adequate. In this situation, it has been suggested that the fractionation of Resovist® shows good performance than Resovist® itself1,2,3). Meito Sangyo has been manufacturing Ferucarbotran, an active pharmaceutical ingredients (API) for Resovist®, since 2001, and are studying to obtain a practicable MPI tracer by separation of Ferucarbotran. Here, we report the physical properties such as MPI signal, particle size, T2 relaxivity and the biological behavior of the fractions from Ferucarbotran.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Separation of Ferucarbotran: A leading candidate of MPI tracer for practical use\",\"authors\":\"S. Nohara, I. Kato, Y. Ito, T. Honma, Y. Ishihara\",\"doi\":\"10.1109/IWMPI.2013.6528339\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It is well known that the possibility of use of Resovist® as a tracer for MPI has been studied, but whose performance using a practicable MPI device is not adequate. In this situation, it has been suggested that the fractionation of Resovist® shows good performance than Resovist® itself1,2,3). Meito Sangyo has been manufacturing Ferucarbotran, an active pharmaceutical ingredients (API) for Resovist®, since 2001, and are studying to obtain a practicable MPI tracer by separation of Ferucarbotran. Here, we report the physical properties such as MPI signal, particle size, T2 relaxivity and the biological behavior of the fractions from Ferucarbotran.\",\"PeriodicalId\":267566,\"journal\":{\"name\":\"2013 International Workshop on Magnetic Particle Imaging (IWMPI)\",\"volume\":\"42 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-03-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2013 International Workshop on Magnetic Particle Imaging (IWMPI)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IWMPI.2013.6528339\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IWMPI.2013.6528339","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Separation of Ferucarbotran: A leading candidate of MPI tracer for practical use
It is well known that the possibility of use of Resovist® as a tracer for MPI has been studied, but whose performance using a practicable MPI device is not adequate. In this situation, it has been suggested that the fractionation of Resovist® shows good performance than Resovist® itself1,2,3). Meito Sangyo has been manufacturing Ferucarbotran, an active pharmaceutical ingredients (API) for Resovist®, since 2001, and are studying to obtain a practicable MPI tracer by separation of Ferucarbotran. Here, we report the physical properties such as MPI signal, particle size, T2 relaxivity and the biological behavior of the fractions from Ferucarbotran.
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