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2013 International Workshop on Magnetic Particle Imaging (IWMPI)最新文献

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Power loss optimized field free line generation for magnetic particle imaging 磁粒子成像中功率损耗优化的无场线生成
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2015-08-31 DOI: 10.1109/iwmpi.2013.6528354
M. Weber, M. Erbe, K. Bente, T. Sattel, T. Buzug
{"title":"Power loss optimized field free line generation for magnetic particle imaging","authors":"M. Weber, M. Erbe, K. Bente, T. Sattel, T. Buzug","doi":"10.1109/iwmpi.2013.6528354","DOIUrl":"https://doi.org/10.1109/iwmpi.2013.6528354","url":null,"abstract":"First magnetic field measurements look promising and show excellent agreement with simulations. Power loss optimization realizes FFL imaging at moderate cooling effort. The gain of sensitivity is directly going to improve image quality. The next step is the complete scanner assembling.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115924527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Large tip solution to dynamic Langevin equation for MPI MPI动态Langevin方程的大尖解
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-06-13 DOI: 10.1109/IWMPI.2013.6528385
D. A. Price, L. Croft, E. Saritas, P. Goodwill, S. Conolly
{"title":"Large tip solution to dynamic Langevin equation for MPI","authors":"D. A. Price, L. Croft, E. Saritas, P. Goodwill, S. Conolly","doi":"10.1109/IWMPI.2013.6528385","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528385","url":null,"abstract":"Here our large-angle physical model of the Langevin equation with magneto-viscous relaxation has been found to agree quite well with the results of a Monte Carlo simulation for dynamic particle behavior in a magnetic field. Furthermore, the magneto-viscous relaxation time constant predicted through this model has been shown to agree with experimental data. Such a model to describe magneto-viscous relaxation effects is important because it allows an optimized selection of magnetic excitation strengths, excitation waveform, and nanoparticle properties. Furthermore, a better understanding of magneto-viscous relaxation may allow the option of deconvolving its effect from the final image to achieve to improve spatial resolution.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117184756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic nanoparticle temperature estimation using AC magnetic filed 利用交流磁场估计磁性纳米粒子的温度
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528326
Jing Zhong, Wenzhong Liu, Ming Zhou, Pu Zhang
{"title":"Magnetic nanoparticle temperature estimation using AC magnetic filed","authors":"Jing Zhong, Wenzhong Liu, Ming Zhou, Pu Zhang","doi":"10.1109/IWMPI.2013.6528326","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528326","url":null,"abstract":"This paper aims to discuss a temperature measurement method based on the harmonic response of the magnetic nanoparticles by using AC magnetization. The simulation indicates that the harmonic response of magnetic nanoparticles in AC applied magnetic field has the potential of temperature probing. From the methods, we can find that the measurement accuracy of harmonics amplitude plays a critical role in the temperature estimation using magnetic nanoparticles.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123056120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
High-power active interference suppression in magnetic particle imaging 磁粒子成像中大功率有源干扰抑制
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528381
B. Zheng, W. Yang, T. Massey, P. Goodwill, S. Conolly
{"title":"High-power active interference suppression in magnetic particle imaging","authors":"B. Zheng, W. Yang, T. Massey, P. Goodwill, S. Conolly","doi":"10.1109/IWMPI.2013.6528381","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528381","url":null,"abstract":"For angiography, stem cell imaging, and cancer imaging, magnetic particle imaging (MPI) can replace conventional techniques due to its safety in vivo, exquisite image contrast, and high detection sensitivity. However, compared to the theoretical physical sensitivity limit of a MPI scanner with 1 mm3 resolution using image 17 nm iron oxide nanoparticles, which lies between 100 nM and 1 μM1, the detection sensitivity for current MPI systems is worse by over 4 orders of magnitude. Factors contributing to this lack of sensitivity include non-optimal noise matching and feedthrough interference, of which the latter is a more dominant effect due to spectral overlap between the interfering signals and particle signals. Gleich et al., Schmale et al. and the authors of this study have previously attempted to decrease the interference through high-power filters and reducing capacitor distortion. In this work, we attempt to actively cancel interfering magnetic fields through the use of a feedforward transformer coupling circuit.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124471800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
ECG signal acquisition within a continuous LF powered region 心电信号采集在一个连续的低频供电区域
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528365
J. Franke, U. Heinen, M. Heidenreich, G. R. Morris, T. Buzug
{"title":"ECG signal acquisition within a continuous LF powered region","authors":"J. Franke, U. Heinen, M. Heidenreich, G. R. Morris, T. Buzug","doi":"10.1109/IWMPI.2013.6528365","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528365","url":null,"abstract":"Neither unwanted MPI signals due to the presence of ECG electrode material within the sensitive Tx/Rx DF nor ECG signal perturbations caused by the 25 kHz DF excitation field have been detected for either electrode type. However, in case of electrode type [A] the maximum observed electrode temperature was 48.8 °C (c.f. Fig 1 LEFT) whereas a temperature of more than 115 °C (c.f. Fig. 1 RIGHT) has been detected in case of electrode type [B].","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116698698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Reduction of image blurring for time-correlation magnetic particle imaging 减少时间相关磁粒子成像图像模糊
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528342
T. Homma, S. Shimizu, Y. Ishihara
{"title":"Reduction of image blurring for time-correlation magnetic particle imaging","authors":"T. Homma, S. Shimizu, Y. Ishihara","doi":"10.1109/IWMPI.2013.6528342","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528342","url":null,"abstract":"Figure 2(a) shows the image reconstructed by the time-correlation method. In this simulation, negative signal components in the iterative processing were ignored. Figure 2(b) shows the reconstructed image after iterative processing. The mean squared error (MSE) was used as the evaluation criterion. The image quality improved up to 2.9 times. However, since the reconstructed image did not converge, an appropriate normalized parameter α should be set. Additionally, noise components were ignored in this experiment. In the future, the proposed method will need to be improved.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"182 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123590019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Estimating particle mobility in MPI MPI中粒子迁移率的估计
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528372
T. Wawrzik, C. Kuhlmann, F. Ludwig, M. Schilling
{"title":"Estimating particle mobility in MPI","authors":"T. Wawrzik, C. Kuhlmann, F. Ludwig, M. Schilling","doi":"10.1109/IWMPI.2013.6528372","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528372","url":null,"abstract":"Numerical simulations and initial measurements with our MPI scanner [3] show that “Mobility”-MPI (mMPI) is a capable extension of the magnetic particle imaging technique which enables binding-state detection.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"172 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116001496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Effect of Brownian relaxation in frequency-dependent magnetic particle spectroscopy measurements 频率相关磁粒子谱测量中布朗弛豫的影响
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528371
T. Wawrzik, C. Kuhlmann, H. Remmer, N. Gehrke, A. Briel, M. Schilling, F. Ludwig
{"title":"Effect of Brownian relaxation in frequency-dependent magnetic particle spectroscopy measurements","authors":"T. Wawrzik, C. Kuhlmann, H. Remmer, N. Gehrke, A. Briel, M. Schilling, F. Ludwig","doi":"10.1109/IWMPI.2013.6528371","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528371","url":null,"abstract":"Our recent experiments show that the transition from Brownian to Néel relaxation regime strongly depends on the particle properties and the analysis of the spectrum for different frequencies reveals the dynamics of the ferrofluid.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"235 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124583424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Quantitative stem cell imaging with magnetic particle imaging 定量干细胞成像与磁颗粒成像
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528323
B. Zheng, T. Vazin, W. Yang, P. Goodwill, E. Saritas, L. Croft, D. Schaffer, S. Conolly
{"title":"Quantitative stem cell imaging with magnetic particle imaging","authors":"B. Zheng, T. Vazin, W. Yang, P. Goodwill, E. Saritas, L. Croft, D. Schaffer, S. Conolly","doi":"10.1109/IWMPI.2013.6528323","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528323","url":null,"abstract":"MPI stem cell imaging - sensitivity and linearity: 9 pelletized, labeled hESC-derived cell populations (Fig. 2A) with varying cell numbers were imaged successively in the FFL imager. Fig. 2B shows the maximum image intensity from each reconstructed cell pellet image as a function of cell number. When a linear fit was applied, we found a strong linear correlation between MPI signal intensity and cell number, with R2 > 0.99. Additionally, the detection sensitivity of the projection MPI system was found to be slightly over 104 cells. We found no detectable MPI signal from unlabeled cell populations. Mice imaging: A MPI image of postmortem cell injections containing 4×105 and 6×105 is shown in Fig. 2C. The MPI image shows excellent contrast with minimal tissue effects. Additionally, the ratio of total MPI signal between the 6×105 and 4×105 injection regions was found to be 1.5, as expected.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123834288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Triggered chemotherapeutic drug release from multi-component nanochains mediated by a local magnetic field 局部磁场介导的多组分纳米链触发化疗药物释放
2013 International Workshop on Magnetic Particle Imaging (IWMPI) Pub Date : 2013-03-23 DOI: 10.1109/IWMPI.2013.6528333
L. Bauer, P. Peiris, R. Toy, E. Tran, J. Pansky, E. Doolittle, E. Schmidt, E. Hayden, A. Mayer, R. Keri, M. Griswold, E. Karathanasis
{"title":"Triggered chemotherapeutic drug release from multi-component nanochains mediated by a local magnetic field","authors":"L. Bauer, P. Peiris, R. Toy, E. Tran, J. Pansky, E. Doolittle, E. Schmidt, E. Hayden, A. Mayer, R. Keri, M. Griswold, E. Karathanasis","doi":"10.1109/IWMPI.2013.6528333","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528333","url":null,"abstract":"Therapeutic efficacy was evaluated by comparing survival times of treated animals with untreated animals and control groups. The mean survival time for animals receiving a single treatment of Drug-NC followed by RF exposure was 25.1 days, compared to 15.2 days for untreated and control groups. A two-cycle treatment prolonged survival to an average of 46 days. Significant cell death was observed in the Drug-NC+RF group in histological sections of the tumors, while nearly no cell death was observed in any of the control groups. The iron oxide nanoparticles used in the chain are an effective tool for converting magnetic energy into mechanical energy. The current application makes use of restricted Brownian motion of the nanoparticles in the nanochain. The movement of the iron oxide chain is restricted due to bonding, preventing true rotation to align with the field.2 We believe the result is a mechanical “vibration” that causes imperfections in the liposome though which the drug is able to escape. To investigate this hypothesis, drug release was measured from several concentrations of Drug-NC exposed to the same magnetic field, and all samples exhibited the same release rate, suggesting that a high concentration of iron oxide nanoparticles is not necessary for drug release. Further, no global heating was observed, and the possibility of local heating was excluded through linking a fluorophore (Alexa 488) to the iron oxide chain of the Drug-NC particle.3 Multiple Drug-NC suspensions were exposed to direct heating (ΔT=0-9°C), causing a measureable decrease in fluorescence intensity. However, when the suspensions were only exposed to RF, no change in fluorescence intensity was observed.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124475381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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