Superparamagnetic nanoparticles in lymphatic tissue - Detection and distribution in a breast cancer model for magnetic particle imaging

Abstract

The SPIOs are moving from the injection site through the lymph-fat tissue to the axillary region and finally into the axillary lymph nodes. SPIOs follows the traces of lymphatic vessels, respecting the borders and spaces between different tissues. They were found in the neighborhood of collagen fibers and accumulates in distinct regions. We present first results of the approach of SNLB with MPI.