P. Vogel, M. A. Ruckert, W. Kullmann, P. Jakob, V. Behr
{"title":"Slice scanning mode for traveling wave MPI","authors":"P. Vogel, M. A. Ruckert, W. Kullmann, P. Jakob, V. Behr","doi":"10.1109/IWMPI.2013.6528369","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528369","url":null,"abstract":"The sample shown in fig. 1B contains a tube with an inner diameter of 860 μm filled with undiluted Resovist® (Bayer-Schering, Germany) embedded in acrylic glass. The acquisition time for one slice is tslice=1/f1, with 4000 averages and f1=920 Hz the overall acquisition time is t=4000/f1=4,35 s. The intrinsic spatial resolution is given by the setup and was calculated to be 2 mm in z- and 4 mm in x-direction. The deconvoluted image (see fig. 1B) shows a good agreement and proves the feasibility of imaging studies, e.g. in pre-clinical context, based on TWMPI.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116254355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brownian and Néel relaxation times in magnetic particle dynamics","authors":"R. Deissler, M. Martens, Y. Wu, R. Brown","doi":"10.1109/IWMPI.2013.6528375","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528375","url":null,"abstract":"The equations for the well-known Brownian and Néel relaxation times T<sub>B</sub> and T<sub>N</sub> (given in the Introduction) are not sufficient to determine whether or not the Néel relaxation mechanism may be neglected. In fact, for a sufficiently large magnetic field strength, the Néel relaxation time can change by many orders of magnitude, whereas the Brownian relaxation time is comparatively insensitive to the magnetic field strength. Therefore, even if τ<sub>N</sub> >> τ<sub>B</sub>, the Néel relaxation mechanism can still be important and even dominate.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114779646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Wojtczyk, A. Timmermeyer, W. Tenner, T. Sattel, G. Bringout, M. Gruttner, M. Graeser, T. Buzug
{"title":"Measure of trajectory quality in Magnetic Particle Imaging","authors":"H. Wojtczyk, A. Timmermeyer, W. Tenner, T. Sattel, G. Bringout, M. Gruttner, M. Graeser, T. Buzug","doi":"10.1109/IWMPI.2013.6528351","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528351","url":null,"abstract":"For all trajectories, the energies computed in time and frequency domain agree well. The maximum local magnetization change dM/dt is largest for the spiral and Lissajous trajectories while it is smallest for the Cartesian trajectory. For the Lissajous and Cartesian trajectories, the total magnetization change appears more homogeneous over the field of view (FOV) than for the radial and spiral trajectories, where it is stronger in the center compared to the borders. In general, areas of homogeneous high total magnetization change seem to correspond to areas of high spatial resolution in reconstructed images.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124757538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Khandhar, R. M. Ferguson, H. Arami, K. Krishnan
{"title":"Physical and biological optimization of core-shell nanoparticle tracers for in vivo MPI","authors":"A. Khandhar, R. M. Ferguson, H. Arami, K. Krishnan","doi":"10.1109/IWMPI.2013.6528377","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528377","url":null,"abstract":"In this study, in vivo particokinetics of biocompatible MNTs that show optimal MPI performance in the biological environment has been presented. In our previous work, the particokinetics - biodistribution and blood circulation time - of poly(ethylene glycol) (PEG)-coated 17 nm core and ~80nm hydrodynamic diameter MNTs in female CD-1 mice was studied. Specifically, the blood-circulation time was characterized by measuring the particle response function (PRF) of MNTs circulating in blood using our 25 kHz magnetic particle spectrometer (MPS). In comparison to Resovist, monodisperse 17 nm MNTs showed 2x greater signal that was sustained for ~15 minutes of circulation in this rodent model. Current modeling and experimental results indicate that ~22-25 nm is the optimal core size at 25 kHz AC-field, thus we present in vivo circulation characteristics of MNT cores in this optimal size range.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132533180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic molecular imaging: Sensitivity, resolution, and specificity","authors":"Li Yao, L. De Silva, Shoujun Xu","doi":"10.1109/IWMPI.2013.6528325","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528325","url":null,"abstract":"Molecular imaging usually employs a labeling technique, mainly optical labeling or magnetic labeling, to highlight target molecules. While optical labeling uses a wavelength parameter to achieve molecular specificity, there is no analogous parameter in magnetic labeling to achieve molecular specificity. In addition, a technique with high sensitivity is required to measure the quantity of the magnetically labeled molecules and provide their spatial information. Using scanning magnetic imaging (SMI) and force-induced remnant magnetization spectroscopy (FIRMS) techniques that are based on atomic magnetometry, we have achieved high sensitivity, good spatial resolution, and molecular specificity for magnetic sensing.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"23 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128926231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of magnetostimulation limits for axial and transverse drive fields in MPI","authors":"Elaine Y Yu, E. Saritas, S. Conolly","doi":"10.1109/IWMPI.2013.6528324","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528324","url":null,"abstract":"As shown in Fig. 1b, the mean magneto stimulation thresholds for the transverse field was approximately 3 times lower than the axial field (ΔBmin = 26 mT-pp vs. 78 mT-pp) for the same set of subjects, with comparable τc values (265 μs vs. 243 μs). In addition, the percentage deviation across subjects was significantly smaller for the transverse field (13%) than the axial field (28%). For both transverse and axial fields, the data trends were well modeled by the hyperbolic amplitude vs. frequency curve, as demonstrated in Fig. 1c for a single subject.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117299587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temperature measurements using static field magnetic particle spectroscopy","authors":"D. Reeves, J. Weaver","doi":"10.1109/IWMPI.2013.6528338","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528338","url":null,"abstract":"Measuring nanoparticle temperature accurately is particularly important as it could be used in hyperthermia, and whereas with the previous version of MSB the large fields of the hyperthermia apparatus would have made temperature measurements very difficult, by decoupling using the perpendicular static field, measurements perpendicular to the large field should now allow spectroscopic data including quantification of nanoparticle temperature.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115492300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Bringout, H. Wojtczyk, W. Tenner, M. Graeser, M. Grüttner, J. Haegele, R. Duschka, Nikolaos Panagiotopoulos, Florian M. Vogt, Joerg Barkhausen, T. Buzug
{"title":"A high power driving and selection field coil for an open MPI scanner","authors":"G. Bringout, H. Wojtczyk, W. Tenner, M. Graeser, M. Grüttner, J. Haegele, R. Duschka, Nikolaos Panagiotopoulos, Florian M. Vogt, Joerg Barkhausen, T. Buzug","doi":"10.1109/IWMPI.2013.6528332","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528332","url":null,"abstract":"Three Litz wires have been used in parallel in order to decrease the layer to layer voltage down to 4 kV and the coil voltage down to 8 kV. A two millimeter thick epoxy plate has been glued between each layer, in order to prevent any electrical breakdown between the layers. A special epoxy has been used to minimize the inner temperature of the coil, which reached 180°C with a dissipated power of 5.2 kW. The use of parallel Litz wire leads to currents having different phase angle in every wire which has to be corrected.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114918092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Grafe, M. Gruttner, T. Sattel, C. Kaethner, T. Buzug
{"title":"Phantom simulation based on measured gradient fields of a single-sided MPI scanner","authors":"K. Grafe, M. Gruttner, T. Sattel, C. Kaethner, T. Buzug","doi":"10.1109/IWMPI.2013.6528352","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528352","url":null,"abstract":"Figure 2 shows the reconstruction result using a simulated selection field and a simulated drive field. The resolution of the reconstruction decreases with the distance to the coil assembly of the single-sided scanner. This result will be used to verify later results.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131382730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Approximated elliptical coils in magnetic particle imaging","authors":"C. Kaethner, K. Grafe, M. Gruttner, T. Buzug","doi":"10.1109/IWMPI.2013.6528343","DOIUrl":"https://doi.org/10.1109/IWMPI.2013.6528343","url":null,"abstract":"The paper presented results of simulated and measured magnetic fields of an approximated elliptical coil. The simulation values are coincided with the measurement values. Using the relative error as difference metric, the difference between simulation and measurement is presented as well. The visual comparison between the images as well as the resulting values of the relative error show only a minimal difference in the inner zone of the coils. The gradient values for the prototype coil arrangement for x, y and z direction were also shown. With an increasing side length the gradients in x and y direction decrease, while the gradient in z direction slightly increases.","PeriodicalId":267566,"journal":{"name":"2013 International Workshop on Magnetic Particle Imaging (IWMPI)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126434697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}