Bioelectrochemistry最新文献

{"title":"Benchmarking anion vs. cation exchange membranes in microbial fuel cells: A comparative study of PTFE and Nafion 117","authors":"Kimia Rostami ,&nbsp;Mostafa Ghasemi ,&nbsp;Mehdi Sedighi ,&nbsp;Ahmad Fauzi Ismail ,&nbsp;Hegazy Rezk ,&nbsp;Jenn-Kun Kuo","doi":"10.1016/j.bioelechem.2025.109083","DOIUrl":"10.1016/j.bioelechem.2025.109083","url":null,"abstract":"<div><div>This study investigates the comparative performance of two types of ion-exchange membranes, polytetrafluoroethylene (PTFE) as an anion exchange membrane (AEM) and Nafion 117 as a cation exchange membrane (CEM), in microbial fuel cells(MFCs). The evaluation focuses on key operational parameters, including power generation, chemical oxygen demand (COD) removal efficiency, and coulombic efficiency (CE). In CEM-based MFCs, protons (H⁺) migrate from the anode to the cathode, whereas in AEM-based systems, hydroxide ions (OH⁻) move from the cathode to the anode. This ion transfer helps maintain pH balance, which is essential for microbial metabolism and catalytic activity. Experimental results demonstrated that the CEM-MFC achieved a power density of 181.5 mW/m² and a COD removal rate of 67 %, while the AEM-MFC produced 272.3 mW/m² and achieved 75 % COD removal. Furthermore, the CE improved from 24.4 % in CEM-MFC to 29 % in AEM-MFC. These results indicate that AEM-MFCs can generate approximately 50 % more power and exhibit enhanced CE, making them more promising candidates for sustainable energy production and wastewater treatment. The superior performance of AEM-MFC is attributed to more favorable microbial activity, better cathodic oxygen reduction reaction (ORR) conditions, and extended pH equilibrium. Additionally, the efficient transfer of OH⁻ ions in AEMs prevents acidification in the anode compartment and supports stable microbial growth. These findings underscore the potential of anion exchange membranes as viable and sustainable alternatives in the design of high-performance MFCs for simultaneous environmental remediation and bioenergy production. This study is a pioneering work that investigates the long-term performance of cost-effective PTFE anion exchange membranes in microbial fuel cells operating with real wastewater (POME), providing crucial insights into pH regulation and microbial stability compared to the benchmark Nafion 117.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109083"},"PeriodicalIF":4.5,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regeneration of tethered bilayer lipid membrane biosensors for repetitive use in toxin detection","authors":"Anastasija Aleksandrovic ,&nbsp;Inga Gabriunaite ,&nbsp;Gintaras Valincius ,&nbsp;Aušra Valiūnienė","doi":"10.1016/j.bioelechem.2025.109078","DOIUrl":"10.1016/j.bioelechem.2025.109078","url":null,"abstract":"<div><div>The development of reusable biosensors based on tethered bilayer lipid membranes (tBLMs) is crucial to achieve cost-effective and sustainable pathogen detection. In this study, we investigated the regeneration of tBLMs assembled on fluorine-doped tin oxide (FTO) substrates using organic silane-based molecular anchors and a lipid mixture of dioleoylphosphatidylcholine and cholesterol. The sensors were exposed to α-hemolysin (αHL), a pore-forming toxin from <em>Staphylococcus aureus</em>, and regenerated by a two-step bilayer removal protocol.</div><div>Electrochemical impedance spectroscopy (EIS) was used to assess the performance of the tBLM before and after each regeneration cycle. A reproducible but systematic shift in the EIS spectra was observed with each cycle, raising questions about the physical origin of this variability. Using an inverse modeling approach to EIS data, we determined that the observed spectral changes were not due to increasing membrane defect density, but rather to a significant decrease in the resistance of the submembrane layer separating the bilayer from the solid substrate, likely due to increased hydration of this layer. This finding was supported by stable mean defect densities and changes in membrane and Helmholtz capacitance.</div><div>Our results demonstrate that tBLMs can be effectively regenerated even after exposure to membrane-disrupting toxins, but the electrochemical characteristics change due to submembrane physicochemical alterations. These insights highlight the importance of controlling submembrane reservoir properties to ensure analytical-grade reproducibility in reusable biosensor platforms. The findings inform future design strategies for robust, repeatable biosensing systems.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109078"},"PeriodicalIF":4.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polythiophene functionalized Ti3C2Tx-TiO2 nanorods composite based electrochemical sensing platform for the detection of Pseudomonas aeruginosa DMC-27b","authors":"Md. Abdul Khaleque ,&nbsp;Md. Arifur Rahman ,&nbsp;Syed Imdadul Hossain ,&nbsp;Md. Romzan Ali ,&nbsp;Md. Ruhul Amin ,&nbsp;Rahman Saidur ,&nbsp;Mohamed Aly Saad Aly ,&nbsp;Munawar Sultana ,&nbsp;Md. Zaved H. Khan","doi":"10.1016/j.bioelechem.2025.109082","DOIUrl":"10.1016/j.bioelechem.2025.109082","url":null,"abstract":"<div><div>Due to its ability to form antibiotic-resistant biofilms, <em>Pseudomonas aeruginosa</em> can cause serious, long-lasting infections, especially in individuals with weakened immune systems; therefore, its rapid detection is crucial for effective treatment. Herein, a polythiophene-functionalized Ti₃C₂T_x-TiO₂ nanorods (NRs) based electrochemical capacitive biosensor is proposed for the determination of <em>Pseudomonas aeruginosa</em> DMC-27b. The capacitive characteristics of the modified electrode were evaluated using a combination of electrochemical methods, such as electrochemical impedance spectroscopy, cyclic voltammetry, galvanostatic discharge, and self-discharging. The incorporation of Ti₃C₂T_x-TiO₂ NRs significantly enhanced both conductivity and charge storage, yielding a specific capacitance of 973.07 F/g. The biosensor demonstrated a sensitive detection range of 10–10⁶ CFU/ml, with a limit of detection of 1.0 CFU/ml. This is the first report on the synthesis of Ti₃C₂T_x-TiO₂ NRs and Ti₃C₂T_x-TiO₂ NRs-doped PTh nanocomposites, and the development of Ti₃C₂T_x-TiO₂ NRs@PTh based electrochemical capacitive biosensor for the detection of <em>Pseudomonas aeruginosa</em>. The biosensor, even with a gradual decline in phage activity, showed good recovery with promising results for detecting the superbug in real samples. Furthermore, the developed Ti₃C₂T_x-TiO₂ NRs@PTh/Phage biosensor exhibited highly selective detection of <em>Pseudomonas aeruginosa</em> DMC-27b, as confirmed by host range and spot test results, and further demonstrated excellent reproducibility and stability.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109082"},"PeriodicalIF":4.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144863847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A highly sensitive ECL biosensor for NF-κB p50 detection based on entropy-driven amplification and CRISPR/Cas12a signal enhancement","authors":"Mengmeng Wang ,&nbsp;Wenjia Zhou ,&nbsp;Meng Wang ,&nbsp;Kai Zhang","doi":"10.1016/j.bioelechem.2025.109081","DOIUrl":"10.1016/j.bioelechem.2025.109081","url":null,"abstract":"<div><div>Transcription factors, particularly NF-κB p50, play crucial roles in regulating gene expression and are involved in several diseases such as cancer, autoimmune disorders, and chronic inflammation. The sensitive detection of NF-κB p50 is essential for clinical diagnostics and therapeutic monitoring. In this study, we present an electrochemiluminescence (ECL) biosensor designed for the highly sensitive and specific detection of NF-κB p50. The biosensor integrates entropy-driven amplification and CRISPR/Cas12a-based signal enhancement to detect trace amounts of NF-κB p50. Upon detection of NF-κB p50, a ternary complex forms with a double-stranded DNA (dsDNA) probe, which prevents subsequent cleavage by exonuclease III (Exo III) and inhibits the CRISPR/Cas12a system. In the absence of NF-κB p50, Exo III digestion triggers entropy-driven amplification, which activates CRISPR/Cas12a, leading to enhanced electrochemical signals. The ECL biosensor demonstrated a detection limit of 0.56 pM, high selectivity, and excellent reproducibility. Furthermore, the biosensor successfully detected NF-κB p50 in complex biological samples, such as HeLa cell lysates, showcasing its potential for clinical applications in disease diagnostics.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109081"},"PeriodicalIF":4.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid carbon nanostructures as efficient electron transfer platforms for lactate biosensing","authors":"Katarzyna Jakubow-Piotrowska,&nbsp;Barbara Kowalewska","doi":"10.1016/j.bioelechem.2025.109080","DOIUrl":"10.1016/j.bioelechem.2025.109080","url":null,"abstract":"<div><div>Two bioelectrocatalytic systems for lactate oxidation were developed by immobilizing lactate oxidase (LOx) onto nanostructured carbon-based platforms: 4-(pyrrole-1-yl)benzoic acid modified multi-walled carbon nanotubes (MWCNT/PyBA) and a hybrid system combining electrochemically reduced graphene oxide with MWCNT/PyBA (ERGO/MWCNT/PyBA). The modification of MWCNT with PyBA enhanced electron transfer between the enzyme's active site and the electrode surface, while the ERGO/MWCNT/PyBA hybrid, prepared via non-covalent π-π stacking interactions, provided improved conductivity and electrocatalytic performance. Both systems exhibited well-defined, reversible FMN/FMNH₂ redox peaks with formal potentials of −0.453 V and −0.446 V vs. Ag/AgCl at pH 7.0, respectively.</div><div>Notably, this study presents the first determination of electron transfer rate constants (<em>k</em>_<em>s</em>) for LOx using Laviron method, yielding values of 3.9 s⁻¹ for MWCNT/PyBA-LOx and 9.5 s⁻¹ for ERGO/MWCNT/PyBA-LOx, confirming the enhanced electron transfer in the hybrid system. Apparent Michaelis-Menten constants (<em>K</em>_<em>M</em>^<em>app</em>) were 73.7 mM and 8.25 mM, respectively, demonstrating higher enzymatic affinity with the hybrid system. These results introduce a novel hybrid nanostructured matrix for enzyme immobilization and highlight its potential in constructing sensitive, rapid, and selective lactate biosensors applicable to real samples such as dairy products, alcoholic beverages, and clinical fluids.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109080"},"PeriodicalIF":4.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144863845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasensitive portable aptamer-electrochemical sensor for point-of-care testing of Alzheimer's biomarker amyloid-β oligomers","authors":"Huawu Mao,&nbsp;Lidong Ding","doi":"10.1016/j.bioelechem.2025.109079","DOIUrl":"10.1016/j.bioelechem.2025.109079","url":null,"abstract":"<div><div>Early and accessible diagnosis of Alzheimer's disease (AD) is crucial for effective intervention, yet current methods like amyloid-PET(positron emission tomography) imaging remain cost-prohibitive and lack scalability. Here, we present a miniaturized electrochemical platform for ultrasensitive detection of amyloid-β oligomers (AβOs), pathogenic biomarkers implicated in early AD progression. The system employs a disposable screen-printed electrode functionalized with gold nanoparticles (AuNPs) and thiolated aptamers, leveraging Au<img>S bonds for oriented aptamer immobilization and AβO-specific recognition. This aptasensor achieves a linear detection range of 10 pg/mL to 100 μg/mL (R² = 0.995) with a limit of detection (LOD) of 2.3 pg/mL (S/N = 3) in human serum, coupled with robust recovery rates (94.9–108.89 %) and low inter-assay variability (RSD &lt; 5.5 %). Integrated with a handheld analyzer (90 × 50 × 8 mm, 30 g) executing differential pulse voltammetry (DPV), the platform wirelessly transmits data to a smartphone app, delivering quantitative results within 20 s at &lt;$1 per test. Preclinical validation using blood from mice injected with AβO protein showed that the platform's test results were highly correlated with the injected dose (R² = 0.995, <em>p</em> &lt; 0.001) and outperformed ELISA in terms of efficiency and cost. By combining laboratory-grade performance, portability, and scalability, the system addresses unmet needs in community-based AD screening and has scalable potential for monitoring neurodegenerative proteomics.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109079"},"PeriodicalIF":4.5,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144886606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitrogen-doped and catalytically modified electrodes in campus-sourced electrogenic microbe-driven MFCs for enhanced copper ion adsorption","authors":"Qinbo Zhang,&nbsp;Bilajia Tan,&nbsp;Haihong Li,&nbsp;Fengqiu An","doi":"10.1016/j.bioelechem.2025.109077","DOIUrl":"10.1016/j.bioelechem.2025.109077","url":null,"abstract":"","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109077"},"PeriodicalIF":4.5,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144813992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nature's first electrical tool: microbial biofilms using electron transfer networks to perform aerobic respiration in an anaerobic environment","authors":"Scott R. Burge ,&nbsp;Kiril Hristovski ,&nbsp;Ljupcho Pejov ,&nbsp;Russell G. Burge ,&nbsp;David Hoffman ,&nbsp;Dragan Boscovic ,&nbsp;Robert Harding","doi":"10.1016/j.bioelechem.2025.109076","DOIUrl":"10.1016/j.bioelechem.2025.109076","url":null,"abstract":"<div><div>Heterotrophic biofilms in an anaerobic chamber exhibit characteristics consistent with extracellular electron transfer (EET) networks capable of storing electrons and transporting them to atmospheric oxygen as the ultimate electron acceptor. Considering this charge storage phenomenon of biofilms, it was hypothesized that EET networks in biofilms would behave like resistor-capacitor (RC) circuits. To test this hypothesis, an experimental system equipped with 48 microbial potentiometric sensor (MPS) electrodes and four reduction/oxidation probes (ORP) was briefly disturbed by introducing a pulse of electron donor compound (acetate), and the generated potentials were monitored over several months to validate a theoretical model that was developed and described the behaviors of RC circuits. The data suggested existence of two electrically isolated systems (biofilm and bulk solution) where the biofilm matrix served as a long-range electrical conduit employed by the biofilm microorganisms in a two-step process: (1) temporary storage of metabolic charge in the temporary electron acceptors (TEAs) within the EET network (assimilation phase) poised at higher potentials than the soluble electron acceptors, and (2) the subsequent transfer of this temporarily stored charge through the electrical gradients of the EET mechanisms (dissipation phase) to ultimate electron acceptor (oxygen) located at a distance. The developed RC model based on a generalized logistic function (Richard's function) described this biofilm behavior with high precision. In brief, the entire biofilm system represents an extracellular “electrical tool” for performing an aerobic respiration in an anaerobic environment. The presented results therefore strongly imply that the observed RC arrangement is compatible with generation of a biological field as nature's first tool for maximizing energy utilization.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109076"},"PeriodicalIF":4.5,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144830504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated photoelectrochemical/photothermal dual-mode biosensor with simultaneous dual-signal output for detection of bladder cancer cells HT-1376","authors":"Qingqing Zhang ,&nbsp;Tingting Zhai ,&nbsp;Jie Chen ,&nbsp;Zhongxiu Chen ,&nbsp;Hao Tan ,&nbsp;Lifen Long ,&nbsp;Tingting Hao ,&nbsp;Zhiyong Guo","doi":"10.1016/j.bioelechem.2025.109075","DOIUrl":"10.1016/j.bioelechem.2025.109075","url":null,"abstract":"<div><div>Here, a photoelectrochemical (PEC)/photothermal (PT) dual-mode biosensing platform with simultaneous output of response signals was developed for sensitive and accurate detection of bladder tumor cells HT-1376. The system utilized an infrared laser as a shared light source, with photocurrent and temperature measurements acquired through parallel PEC and PT detection channels. The HT-1376-specific aptamer (Apt) was covalently immobilized on aminated indium‑tin oxide (ITO) electrode via glutaraldehyde crosslinking between surface amino groups and amine-modified aptamer terminals, enabling selective target capture. Following aptamer-HT-1376 recognition, the dual-mode tags CuO@NPC functionalized with aptamer (CuO@NPC-Apt) were assembled on the electrode surface, triggering simultaneous PEC and PT signal responses. Under optimized conditions, linear detection ranges of 5–10⁵ cells/mL (PEC mode) and 10–10⁵ cells/mL (PT mode) were achieved, with limits of detection (LOD) of 3 cells/mL (PEC) and 5 cells/mL (PT). The platform exhibited excellent signal stability, repeatability and selectivity. This dual-mode strategy provides a reliable analytical method for HT-1376 quantification, demonstrating potential for clinical cancer diagnostics.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109075"},"PeriodicalIF":4.5,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma jet and plasma treated aerosol induced permeation of reconstructed human epidermis","authors":"Vinodini Vijayarangan ,&nbsp;Zeineb Maaroufi ,&nbsp;Amaury Rouillard ,&nbsp;Septuce Gaetan-Zin ,&nbsp;Sébastien Dozias ,&nbsp;Pablo Escot-Bocanegra ,&nbsp;Augusto Stancampiano ,&nbsp;Catherine Grillon ,&nbsp;Eric Robert","doi":"10.1016/j.bioelechem.2025.109060","DOIUrl":"10.1016/j.bioelechem.2025.109060","url":null,"abstract":"<div><div>As plasma-treated liquids have many applications in plasma medicine, their cutaneous effects for cosmetic purposes are also considered as an alternative way to treat skin without the electric hazards and limitations correlated with the use of a direct plasma. Our previous work on human skin explants showed increased transdermal diffusion of cosmetic ingredients (caffeine, hyaluronic acid) after direct plasma treatment. Despite this proven efficacy, these protocols still face limitations dealing with toxicity, small treatment areas and uneven surface coverage. To overcome these limitations and broaden the scope of non-thermal-plasma-based technology for skin care, this study presents for the first time the development and assessment of a plasma aerosol device to nebulize plasma-treated liquids on skin models.</div><div>This work demonstrates how plasma jet and plasma treated aerosol can temporarily enhance permeation in reconstructed human epidermis (RHE), using fluorescein as a probe, under safe plasma delivery conditions. Transepithelial electrical resistance measurements confirm the transient nature of the plasma-induced modulation, suggesting the possibility to control the duration of the enhanced permeation. Overall, the achieved results demonstrate the potential of plasma jet and plasma treated aerosol to safely control diffusion through skin for cosmetic and medical purposes.</div></div>","PeriodicalId":252,"journal":{"name":"Bioelectrochemistry","volume":"167 ","pages":"Article 109060"},"PeriodicalIF":4.5,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}