ACS Sensors最新文献_第8页

A DNA Fishhook Electrochemical Sensor Based on a Potassium Ferricyanide-Mediated Dual-Signal-Correlation Enhanced Electrocatalysis Reaction for a Simultaneous and Correlation Assay of Multiple Biomarkers. 基于铁氰化钾介导的双信号相关增强电催化反应的DNA鱼钩电化学传感器，用于多种生物标志物的同时和相关分析。

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.4c03142

Guanyu Chen,Lilan Xu,Zhuhua Chen,Lifang Lin,Wenlu Wang,Mingzhu Chen,Weiming Sun,Xiaobing Huang,Xi Zhang,Jinghua Chen

{"title":"A DNA Fishhook Electrochemical Sensor Based on a Potassium Ferricyanide-Mediated Dual-Signal-Correlation Enhanced Electrocatalysis Reaction for a Simultaneous and Correlation Assay of Multiple Biomarkers.","authors":"Guanyu Chen,Lilan Xu,Zhuhua Chen,Lifang Lin,Wenlu Wang,Mingzhu Chen,Weiming Sun,Xiaobing Huang,Xi Zhang,Jinghua Chen","doi":"10.1021/acssensors.4c03142","DOIUrl":"https://doi.org/10.1021/acssensors.4c03142","url":null,"abstract":"Simultaneous detection and correlation analysis of multiple biomarkers in a single run are crucial to improving the detection specificity and indicate disease progression, but they remain a challenge. Herein, we propose a DNA fishhook electrochemical sensor based on the potassium ferricyanide-mediated dual-signal correlation enhanced electrocatalysis reaction (DEER). The designed T-shaped DNA fishhook scaffold has two \"hooks\" to recruit their respective \"fish\" (targets) with the help of the \"fishing bait\" (signal probes, Sp), resulting in the different targets and Sp being specifically captured by the DNA fishhook to the electrode interface, respectively. The proposed DEER not only effectively improves the detection sensitivity without introducing nucleic acid amplification but also can reflect the logical correlation between the targets. As proof of principle, the DNA fishhook sensor was successfully applied in the simultaneous detection of two related gene sequences of SARS-CoV-2 and the active-state assay of the PI3K/AKT signaling pathway. In general, our DNA fishhook sensor provides a meaningful potential tool for the sensitive simultaneous detection and correlation analysis of multiple targets.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"28 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mobile Sleep Stage Analysis Using Multichannel Wearable Devices Integrated with Stretchable Transparent Electrodes. 利用集成可拉伸透明电极的多通道可穿戴设备进行移动睡眠阶段分析。

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.4c03602

Hyun-Kyung Um,Eunseo Noh,Chaehwa Yoo,Hyang Woon Lee,Je-Won Kang,Byoung Hoon Lee,Jung-Rok Lee

{"title":"Mobile Sleep Stage Analysis Using Multichannel Wearable Devices Integrated with Stretchable Transparent Electrodes.","authors":"Hyun-Kyung Um,Eunseo Noh,Chaehwa Yoo,Hyang Woon Lee,Je-Won Kang,Byoung Hoon Lee,Jung-Rok Lee","doi":"10.1021/acssensors.4c03602","DOIUrl":"https://doi.org/10.1021/acssensors.4c03602","url":null,"abstract":"The prevalence of sleep disorders in the aging population and the importance of sleep quality for health have emphasized the need for accurate and accessible sleep monitoring solutions. Polysomnography (PSG) remains the clinical gold standard for diagnosing sleep disorders; however, its discomfort and inconvenience limit its accessibility. To address these issues, a wearable device (WD) integrated with stretchable transparent electrodes (STEs) is developed in this study for multisignal sleep monitoring and artificial intelligence (AI)-driven sleep staging. Utilizing conductive and flexible STEs, the WD records multiple biological signals (electroencephalogram [EEG], electrooculogram [EOG], electromyogram [EMG], photoplethysmography, and motion data) with high precision and low noise, comparable to PSG (<4 μVRMS). It achieves a 73.2% accuracy and a macro F1 score of 0.72 in sleep staging using an AI model trained on multisignal inputs. Notably, accuracy marginally improves when using only the EEG, EOG, and EMG channels, which may simplify future device designs. This WD offers a compact, multisignal solution for at-home sleep monitoring, with the potential for use as an evaluation tool for personalized sleep therapies.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"232 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paper-Based Vertical Flow Assays for in Vitro Diagnostics and Environmental Monitoring. 用于体外诊断和环境监测的基于纸张的垂直流动试验。

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c00668

Jaehyung Jeon,Heeseon Choi,Gyeo-Re Han,Rajesh Ghosh,Barath Palanisamy,Dino Di Carlo,Aydogan Ozcan,Sungsu Park

{"title":"Paper-Based Vertical Flow Assays for in Vitro Diagnostics and Environmental Monitoring.","authors":"Jaehyung Jeon,Heeseon Choi,Gyeo-Re Han,Rajesh Ghosh,Barath Palanisamy,Dino Di Carlo,Aydogan Ozcan,Sungsu Park","doi":"10.1021/acssensors.5c00668","DOIUrl":"https://doi.org/10.1021/acssensors.5c00668","url":null,"abstract":"Microfluidic paper-based analytical devices (μPADs) are powerful tools for diagnostic and environmental monitoring. Being affordable and portable, μPADs enable rapid detection of small molecules, heavy metals, and biomolecules, thereby decentralizing diagnostics and expanding biosensor accessibility. However, the reliance on two-dimensional fluid flow restricts the utility of conventional μPADs, presenting challenges for applications that require simultaneous multibiomarker analysis from a single sample. Vertical flow paper-based analytical devices (VF-μPADs) overcome this challenge by allowing axial fluid movement through paper stacks, offering several advantages, including (1) enhanced multiplexing capabilities, (2) reduced hook effect for improved accuracy, and (3) shorter assay times. This review provides an overview of VF-μPADs technologies, exploring structural and functional performance trade-offs between VF-μPADs and conventional lateral flow systems. The sensing performance, fabrication methods, and applications in in vitro diagnostics and environmental monitoring are discussed. Furthermore, critical challenges─such as fabrication complexity, data analysis, and scalability─are addressed, along with proposed strategies for mitigating these barriers to facilitate broader adoption. By examining these strengths and challenges, this review presents the potential of VF-μPADs to advance point-of-care testing, particularly in resource-limited settings.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"74 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancement of Hydrogen-Sensing Properties of Pd-Modified WO3 Nanocubes via Tannic Acid-Assisted Surface Functionalization 单宁酸辅助表面功能化增强pd修饰WO3纳米立方的氢敏感性能

IF 8.2 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c0026810.1021/acssensors.5c00268

Shaohai Wu, Weijiang Gan, Xianren Zhou, Zhini Bin, Jun Chen, Wang Li, Huajun Lai* and Zhongmin Wang*,

{"title":"Enhancement of Hydrogen-Sensing Properties of Pd-Modified WO3 Nanocubes via Tannic Acid-Assisted Surface Functionalization","authors":"Shaohai Wu, Weijiang Gan, Xianren Zhou, Zhini Bin, Jun Chen, Wang Li, Huajun Lai* and Zhongmin Wang*, ","doi":"10.1021/acssensors.5c0026810.1021/acssensors.5c00268","DOIUrl":"https://doi.org/10.1021/acssensors.5c00268https://doi.org/10.1021/acssensors.5c00268","url":null,"abstract":"The growing use of hydrogen as a clean energy source demands the development of efficient and reliable sensors to ensure safety. Traditional metal–oxide–semiconductors, particularly WO3, face challenges such as limited sensitivity, high operating temperatures, and slow response times. The present study explores the enhancement of hydrogen-sensing properties through the modification of WO3 with Pd nanoparticles utilizing tannic acid (TA)-assisted surface functionalization. Due to its branched molecular structure and inherent phenolic characteristics, TA plays a significant role as a mediator in facilitating the adsorption of Pd onto the surface of WO3. Furthermore, TA effectively prevents the agglomeration of Pd, a result of the unique growth patterns of TA observed during high-temperature pyrolysis. Optimal content of Pd and TA is 0.10 atom % and 0.25 g, respectively. The gas sensor of 0.25 g TA@WO3-0.10 atom % Pd exhibits remarkable sensitivity with a response value of 456, alongside a rapid response time of 1 s at 200 °C toward 500 ppm hydrogen. Additionally, the gas sensor demonstrates excellent stability and reproducibility over multiple cycles. The enhanced performance is attributed to the synergistic effect of the formation of oxygen vacancies increasing active sites, the uniform dispersion of Pd nanoparticles facilitated by TA, and the catalytic activity of Pd accelerating hydrogen adsorption and reaction kinetics. This research highlights the potential of ecofriendly materials to enhance hydrogen sensor performance for safety monitoring.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"10 5","pages":"3600–3609 3600–3609"},"PeriodicalIF":8.2,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robust Odor Detection in Electronic Nose Using Transfer-Learning Powered Scentformer Model 基于迁移学习驱动Scentformer模型的电子鼻鲁棒气味检测

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c00630

Wangze Ni, Tao Wang, Yu Wu, Lechen Chen, Min Zeng, Jianhua Yang, Nantao Hu, Bowei Zhang, Fuzhen Xuan, Zhi Yang

{"title":"Robust Odor Detection in Electronic Nose Using Transfer-Learning Powered Scentformer Model","authors":"Wangze Ni, Tao Wang, Yu Wu, Lechen Chen, Min Zeng, Jianhua Yang, Nantao Hu, Bowei Zhang, Fuzhen Xuan, Zhi Yang","doi":"10.1021/acssensors.5c00630","DOIUrl":"https://doi.org/10.1021/acssensors.5c00630","url":null,"abstract":"Mimicking the olfactory system of humans, the use of electronic noses (E-noses) for the detection of odors in nature has become a hot research topic. This study presents a novel E-nose based on deep learning architecture called Scentformer, which addresses the limitations of the current E-nose like a narrow detection range and limited generalizability across different scenarios. Armed with a self-adaptive data down-sampling method, the E-nose is capable of detecting 55 different natural odors with the classification accuracy of 99.94%, and the model embedded in the E-nose is analyzed using Shapley Additive exPlanations analysis, providing a quantitative interpretation of the E-nose performance. Furthermore, leveraging Scentformer’s transfer learning ability, the E-nose efficiently adapts to new odors and gases. Rather than retraining all layers of the model on the new odor data set, only the fully connected layers need to be trained for the pretrained model. Using only 1‰ data of the retrained model, the pretrained model-based E-nose can also achieve classification accuracies of 99.14% across various odor and gas concentrations. This provides a robust approach to the detection of diverse direct current signals in real-world applications.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"5 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutting-Edge Exploration of a Molecularly Imprinted Polymer-Coupled Electrochemiluminescence Mechanism Based on Organic Cation Side-Chain Construction for the Identification and Detection of Escherichia coli O157: H7. 基于有机阳离子侧链构建的分子印迹聚合物偶联电化学发光机制的前沿探索用于鉴定和检测大肠杆菌O157: H7

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c00172

Xin Wang,Xufeng Zang,Chunyi Hu,Jiazhan Li,Bo Cui,Yishan Fang

{"title":"Cutting-Edge Exploration of a Molecularly Imprinted Polymer-Coupled Electrochemiluminescence Mechanism Based on Organic Cation Side-Chain Construction for the Identification and Detection of Escherichia coli O157: H7.","authors":"Xin Wang,Xufeng Zang,Chunyi Hu,Jiazhan Li,Bo Cui,Yishan Fang","doi":"10.1021/acssensors.5c00172","DOIUrl":"https://doi.org/10.1021/acssensors.5c00172","url":null,"abstract":"In this paper, an organic semiconductor bacterial biosensor was developed for selective detection of facultative anaerobic Escherichia coli O157: H7, which combines electrochemiluminescence (ECL) and bacterial imprinted polymer technologies. Fe2+ and Mn2+ were used to prepare irregular nanocluster ECL emitters (Fe-Mn NCs) via Cu2O, which served as excellent catalysts in the cathodic coreactant (K2S2O8) reaction system, to enhance the ECL signal intensity. Through electropolymerization, the cationic side chains of functional monomers could bind to proteins (such as cytochrome proteins) on the cell membrane of E. coli O157: H7 under aerobic conditions, and transfer to the interior of E. coli O157: H7 and participate in the cyclic regeneration of nicotinamide adenine dinucleotide, which greatly amplifies the detected ECL signal and accelerates the consumption of oxygen by the respiratory chain. When oxygen was consumed, lactic acid was produced by bacteria during the low-oxygen process, in which E. coli O157: H7 can cause a change in the direction of electron flow, resulting in a reduction in the production of SO4•- and a significant decrease in the ECL signal. And when oxygen was readded to the system, the ECL signal recovers or becomes even stronger, where the mechanism of action of cationic semiconductors in this system had been well elucidated. This sensor has a good linear relationship in the range of 101-108 CFU/mL, with a detection limit of 2.29 CFU/mL (S/N = 3), which offers a new detection method for foodborne pathogens, as well as a rapid and accessible identification tool for different types of microorganisms.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"32 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atomic Layer-Modified 3D Pd Nanochannels for High-Performance Hydrogen Sensing 用于高性能氢传感的原子层修饰3D Pd纳米通道

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c00886

Ahyeon Cho, Hojin Kang, Youngwook Cho, Hee-Tae Jung, Heeyeop Chae, Soo-Yeon Cho

{"title":"Atomic Layer-Modified 3D Pd Nanochannels for High-Performance Hydrogen Sensing","authors":"Ahyeon Cho, Hojin Kang, Youngwook Cho, Hee-Tae Jung, Heeyeop Chae, Soo-Yeon Cho","doi":"10.1021/acssensors.5c00886","DOIUrl":"https://doi.org/10.1021/acssensors.5c00886","url":null,"abstract":"Palladium (Pd), known for its excellent H2 adsorption properties and ability to form palladium hydride (PdHx), is extensively utilized as a key material in hydrogen (H2) sensing technologies. Nevertheless, conventional Pd-based H2 sensors have shown limited performance enhancements due to challenges in precisely controlling the microscopic interfaces between Pd nanograins, which determine the total resistance signal of the sensors. This limitation arises from the lack of a technique capable of precisely manipulating these interfaces at the atomic level. In this study, we develop an atomic layer etching (ALE) technique to enhance the performance of Pd-based H2 sensors by enabling precise atomic-scale control over the surface of Pd nanochannels. We fabricated 3D Pd nanopatterns with ultrasmall grain sizes through a top-down nanolithography process, followed by an ALE process that achieved atomic-level precision (10 Å resolution) without compromising material crystallinity. Our two-step ALE process, comprising surface modification with Cl2 plasma and removal with NH3 ligand addition, enables uniform etching across a 4 in. wafer with less than 1% variation in etch per cycle (EPC). This atomic-level modulation of Pd nanochannels resulted in significantly enhanced H2 sensitivity, demonstrating a maximum 130-fold increase in response to 1% H2 concentration compared to nonatomically controlled sensors. Such substantial enhancement has been difficult to achieve through conventional structural tuning methods and is attributed to the maximized volume change of PdHx resulting from the expanded gaps between Pd grains. This platform provides a promising avenue for developing high-performance H2 sensors and other noble-metal-based applications requiring atomic-level structural precision.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"17 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paper-Based Vertical Flow Assays for in Vitro Diagnostics and Environmental Monitoring 用于体外诊断和环境监测的基于纸张的垂直流动试验

IF 8.2 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c0066810.1021/acssensors.5c00668

Jaehyung Jeon, Heeseon Choi, Gyeo-Re Han, Rajesh Ghosh, Barath Palanisamy, Dino Di Carlo, Aydogan Ozcan* and Sungsu Park*,

{"title":"Paper-Based Vertical Flow Assays for in Vitro Diagnostics and Environmental Monitoring","authors":"Jaehyung Jeon, Heeseon Choi, Gyeo-Re Han, Rajesh Ghosh, Barath Palanisamy, Dino Di Carlo, Aydogan Ozcan* and Sungsu Park*, ","doi":"10.1021/acssensors.5c0066810.1021/acssensors.5c00668","DOIUrl":"https://doi.org/10.1021/acssensors.5c00668https://doi.org/10.1021/acssensors.5c00668","url":null,"abstract":"Microfluidic paper-based analytical devices (μPADs) are powerful tools for diagnostic and environmental monitoring. Being affordable and portable, μPADs enable rapid detection of small molecules, heavy metals, and biomolecules, thereby decentralizing diagnostics and expanding biosensor accessibility. However, the reliance on two-dimensional fluid flow restricts the utility of conventional μPADs, presenting challenges for applications that require simultaneous multibiomarker analysis from a single sample. Vertical flow paper-based analytical devices (VF-μPADs) overcome this challenge by allowing axial fluid movement through paper stacks, offering several advantages, including (1) enhanced multiplexing capabilities, (2) reduced hook effect for improved accuracy, and (3) shorter assay times. This review provides an overview of VF-μPADs technologies, exploring structural and functional performance trade-offs between VF-μPADs and conventional lateral flow systems. The sensing performance, fabrication methods, and applications in in vitro diagnostics and environmental monitoring are discussed. Furthermore, critical challenges─such as fabrication complexity, data analysis, and scalability─are addressed, along with proposed strategies for mitigating these barriers to facilitate broader adoption. By examining these strengths and challenges, this review presents the potential of VF-μPADs to advance point-of-care testing, particularly in resource-limited settings.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"10 5","pages":"3317–3339 3317–3339"},"PeriodicalIF":8.2,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancement of Hydrogen-Sensing Properties of Pd-Modified WO3 Nanocubes via Tannic Acid-Assisted Surface Functionalization 单宁酸辅助表面功能化增强pd修饰WO3纳米立方的氢敏感性能

IF 8.9 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c00268

Shaohai Wu, Weijiang Gan, Xianren Zhou, Zhini Bin, Jun Chen, Wang Li, Huajun Lai, Zhongmin Wang

{"title":"Enhancement of Hydrogen-Sensing Properties of Pd-Modified WO3 Nanocubes via Tannic Acid-Assisted Surface Functionalization","authors":"Shaohai Wu, Weijiang Gan, Xianren Zhou, Zhini Bin, Jun Chen, Wang Li, Huajun Lai, Zhongmin Wang","doi":"10.1021/acssensors.5c00268","DOIUrl":"https://doi.org/10.1021/acssensors.5c00268","url":null,"abstract":"The growing use of hydrogen as a clean energy source demands the development of efficient and reliable sensors to ensure safety. Traditional metal–oxide–semiconductors, particularly WO3, face challenges such as limited sensitivity, high operating temperatures, and slow response times. The present study explores the enhancement of hydrogen-sensing properties through the modification of WO3 with Pd nanoparticles utilizing tannic acid (TA)-assisted surface functionalization. Due to its branched molecular structure and inherent phenolic characteristics, TA plays a significant role as a mediator in facilitating the adsorption of Pd onto the surface of WO3. Furthermore, TA effectively prevents the agglomeration of Pd, a result of the unique growth patterns of TA observed during high-temperature pyrolysis. Optimal content of Pd and TA is 0.10 atom % and 0.25 g, respectively. The gas sensor of 0.25 g TA@WO3-0.10 atom % Pd exhibits remarkable sensitivity with a response value of 456, alongside a rapid response time of 1 s at 200 °C toward 500 ppm hydrogen. Additionally, the gas sensor demonstrates excellent stability and reproducibility over multiple cycles. The enhanced performance is attributed to the synergistic effect of the formation of oxygen vacancies increasing active sites, the uniform dispersion of Pd nanoparticles facilitated by TA, and the catalytic activity of Pd accelerating hydrogen adsorption and reaction kinetics. This research highlights the potential of ecofriendly materials to enhance hydrogen sensor performance for safety monitoring.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"8 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atomic Layer-Modified 3D Pd Nanochannels for High-Performance Hydrogen Sensing 用于高性能氢传感的原子层修饰3D Pd纳米通道

IF 8.2 1区化学

ACS Sensors Pub Date : 2025-05-15 DOI: 10.1021/acssensors.5c0088610.1021/acssensors.5c00886

Ahyeon Cho, Hojin Kang, Youngwook Cho, Hee-Tae Jung*, Heeyeop Chae* and Soo-Yeon Cho*,

{"title":"Atomic Layer-Modified 3D Pd Nanochannels for High-Performance Hydrogen Sensing","authors":"Ahyeon Cho, Hojin Kang, Youngwook Cho, Hee-Tae Jung*, Heeyeop Chae* and Soo-Yeon Cho*, ","doi":"10.1021/acssensors.5c0088610.1021/acssensors.5c00886","DOIUrl":"https://doi.org/10.1021/acssensors.5c00886https://doi.org/10.1021/acssensors.5c00886","url":null,"abstract":"Palladium (Pd), known for its excellent H2 adsorption properties and ability to form palladium hydride (PdHx), is extensively utilized as a key material in hydrogen (H2) sensing technologies. Nevertheless, conventional Pd-based H2 sensors have shown limited performance enhancements due to challenges in precisely controlling the microscopic interfaces between Pd nanograins, which determine the total resistance signal of the sensors. This limitation arises from the lack of a technique capable of precisely manipulating these interfaces at the atomic level. In this study, we develop an atomic layer etching (ALE) technique to enhance the performance of Pd-based H2 sensors by enabling precise atomic-scale control over the surface of Pd nanochannels. We fabricated 3D Pd nanopatterns with ultrasmall grain sizes through a top-down nanolithography process, followed by an ALE process that achieved atomic-level precision (10 Å resolution) without compromising material crystallinity. Our two-step ALE process, comprising surface modification with Cl2 plasma and removal with NH3 ligand addition, enables uniform etching across a 4 in. wafer with less than 1% variation in etch per cycle (EPC). This atomic-level modulation of Pd nanochannels resulted in significantly enhanced H2 sensitivity, demonstrating a maximum 130-fold increase in response to 1% H2 concentration compared to nonatomically controlled sensors. Such substantial enhancement has been difficult to achieve through conventional structural tuning methods and is attributed to the maximized volume change of PdHx resulting from the expanded gaps between Pd grains. This platform provides a promising avenue for developing high-performance H2 sensors and other noble-metal-based applications requiring atomic-level structural precision.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"10 5","pages":"3774–3784 3774–3784"},"PeriodicalIF":8.2,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0