{"title":"A comprehensive review of in vitro precursor feeding strategies for the overproduction of high-value plant secondary metabolites","authors":"Muhammad Rifqi Nur Ramadani, Nurul Jadid","doi":"10.1016/j.arabjc.2024.106018","DOIUrl":"10.1016/j.arabjc.2024.106018","url":null,"abstract":"<div><div>Plant tissue culture techniques have revolutionized various aspects of modern agriculture, horticulture, and pharmaceutical industries. This method contributes to enhancing the production of plant secondary metabolites, which have noteworthy applications in pharmaceuticals, agriculture, and industry. Presently, over 50,000 plant metabolites have been identified and categorized into three primary groups: terpenoids, flavonoids, and alkaloids. Numerous studies have elucidated the metabolic pathways involved in the biosynthesis of plant compounds to better understand the metabolic flux, with the aim of identifying and engineering the production of valuable constituents. <em>In vitro</em> precursor feeding is one phytochemical strategy that helps increase the accumulation of plant compounds. Therefore, this review focuses on investigating the application of <em>in vitro</em> precursor feedings to the overproduction of a high-value phytochemicals. Moreover, it evaluates the influence of type and concentration of precursors, plant species and culture conditions as well as the phytochemical products providing insights into optimization strategies. Additionally, the potential application of accumulated terpenoids, flavonoids, and alkaloid-derived compounds for agricultural, pharmaceutical, and industrial purposes are discussed. Finally, perspective challenges and limitations related to <em>in vitro</em> precursor feeding strategy are addressed, including production stability, cytotoxicity effect, and uptake efficiency. The overall data presented might serve as an up-to-date report on the application of <em>in vitro</em> precursor feedings for enhancing plant secondary metabolite production.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106018"},"PeriodicalIF":5.3,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chuanmao Zheng , Jieqing Li , Honggao Liu , Yuanzhong Wang
{"title":"Rapid and non-invasive estimation of total phenol content and species identification in dried wild edible bolete using FT-NIR spectroscopy","authors":"Chuanmao Zheng , Jieqing Li , Honggao Liu , Yuanzhong Wang","doi":"10.1016/j.arabjc.2024.106011","DOIUrl":"10.1016/j.arabjc.2024.106011","url":null,"abstract":"<div><div>The market for dried wild edible mushrooms is characterized by quality discrepancies and species disorganization, which are a matter of concern. The feasibility of using fourier transform near-infrared (FT-NIR) spectroscopy with chemometrics to predict the total phenol content and identify species was investigated in dried bolete. For the determination of total phenolic content, FT-NIR spectral acquisition, and two-dimensional correlation spectroscopy (2DCOS) image acquisition, five common species of dried edible bolete (n = 144) were utilized. The results showed that partial least squares regression (PLSR) combined with Fourier transform near-infrared spectroscopy could predict the total phenol content of dried boletes, with the best prediction coefficient of determination (R<sup>2</sup>p) = 0.79. The partial least squares discriminant analysis (PLS-DA) model accurately identified <em>Phlebopus portentosus</em>, with Matthews correlation coefficient (MCC), Precision (PRC), Sensitivity (SEN), and Specificity (SPE) all being 1. The support vector machines (SVM) model is performed optimally to identify processing edible bolete (<em>Lanmaoa asiatica</em>) with an accuracy of 100 % in the test set. 2DCOS images combined with the residual convolutional neural networks (ResNet) model demonstrated the feasibility of FT-NIR full spectral bands (10,000–4,000 cm<sup>−1</sup>) and characteristic spectral bands (6,500–4,000 cm<sup>−1</sup>) for species identification of boletes. The method applies to the case of consistent or inconsistent sample sizes between groups, with an accuracy of 1.00 for both the training and test sets. The study serves as a rapid, non-invasive, and convenient method for real-time evaluation of the quality of dried edible bolete in the market.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106011"},"PeriodicalIF":5.3,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chen Wang , Zhijie You , Yihui He , Siqi Chen , Xin Chen , Shuang Qu , Ning Zhao , Xin Chen
{"title":"Interaction of xanthoxyletin with protein, molecular docking and antitumor activity in human chronic myeloid leukemia K562 cells","authors":"Chen Wang , Zhijie You , Yihui He , Siqi Chen , Xin Chen , Shuang Qu , Ning Zhao , Xin Chen","doi":"10.1016/j.arabjc.2024.106015","DOIUrl":"10.1016/j.arabjc.2024.106015","url":null,"abstract":"<div><div>Xanthoxyletin (C<sub>15</sub>H<sub>14</sub>O<sub>4</sub>), a natural linear pyranocoumarin, is known to trigger anti-cancer activities, although its anticancer mechanisms are largely unknown. Human hemoglobin (HHb) as a major plasma protein could play a key role in the transportation and biodistribution of therapeutic molecules In this study, the interaction of xanthoxyletin with HHb was measured under physiological conditions using multi-spectroscopic techniques along with molecular docking simulation. Also, the interaction of xanthoxyletin with human chronic myeloid leukemia K562 cells was assessed by cellular assays. It was deduced that each xanthoxyletin molecule shows a thermodynamically favorable interaction with one molecule of HHb with a binding constant (K<sub>b</sub>) in the orders of 10<sup>3-4</sup> M<sup>−1</sup>. These interactions did not significantly result in the loss of α-helical content of HHb. In silico studies supported the experimental findings and demonstrated that non-covalent forces including hydrogen bonds (Ala88 and Arg92), pi-pi stacking (Trp37), and hydrophobic interactions (and Pro95 and Pro36) are the main forces contributing to the xanthoxyletin-HHb complex formation. Cellular and molecular assays showed that xanthoxyletin mitigated the proliferation of K562 cells through apoptosis induction mediated by overexpression of p53, caspase-3, and PARP cleavage. This data may hold great promise for the development of anticancer compounds with potential blood protein binding stemming from xanthoxyletin derivatives/hybrids.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106015"},"PeriodicalIF":5.3,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qian Liu , Wanqiu Jing , Wansheng Yang, Min Huang, Ping Lu, Deyu Hu
{"title":"Green manure (Raphanus stativus L.) alters soil microbial structure and promotes acetochlor degradation","authors":"Qian Liu , Wanqiu Jing , Wansheng Yang, Min Huang, Ping Lu, Deyu Hu","doi":"10.1016/j.arabjc.2024.106017","DOIUrl":"10.1016/j.arabjc.2024.106017","url":null,"abstract":"<div><div>Microorganisms play important roles in the remediation of contaminated soil. However, the relationship between the soil microbial communities and herbicide degradation remains unclear after applying green manure. The aim of this study was to investigate the effect of green manure on soil physicochemical properties, between acetochlor degradation and microbial communities. Adoption of pot experiments, the effects and mechanism of four fertilization treatments (CK: without green manure; GMV: <em>Vicia villosa</em> Roth; GML: <em>Lolium perenne</em> L.; GMR: <em>Raphanus stativus</em> L.) on the degradation of acetochlor were evaluated. Appling to <em>Raphanus stativus</em> L., acetochlor degraded in 5.82 days, which was 74.81 % higher than that of CK. Community differences in soil microbes were analysed using high-throughput sequencing. The predominant phyla of fungi were <em>Ascomyocta</em>, <em>Mortierellomycota</em>, <em>Basidiomycota</em>, unclassified_k_Fungi, and <em>Chytridiomycota</em>, which accounted for 85.01 %–116.46 % of the fungal OTUs. The green manure treatment showed higher abundance of <em>Mortierella</em> (9.54 %–13.05 %), diversity of saprotrophic fungi and symbiotic fungi and faster rate of degradation of acetochlor as compared to CK. In addition, soil properties such as soil total phosphorus (TP) and pH have significant effects on microorganisms. Fungal functional analysis revealed that the microorganisms associated with acetochlor biodegradation mainly belonged to <em>Ascomycota</em> and <em>Glomeromycota</em>. This study offers new insights into the relationship between soil properties and the environmental risks associated with the presence of pesticides in soil and the related mechanisms.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106017"},"PeriodicalIF":5.3,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zheng Wu, Shujuan Cheng, Shaoping Wang, Wenzheng Li, Jinghua Liu
{"title":"Biological evaluation of sophoridine by interaction with plasma transport protein and protective effects in cardiomyocytes","authors":"Zheng Wu, Shujuan Cheng, Shaoping Wang, Wenzheng Li, Jinghua Liu","doi":"10.1016/j.arabjc.2024.106014","DOIUrl":"10.1016/j.arabjc.2024.106014","url":null,"abstract":"<div><div>Numerous studies have demonstrated the protective benefits of sophoridine, a bioactive alkaloid, on cell damage. However, its primary biological properties such as interaction with plasma protein, which serves as the primary drug carrier, and its cardioprotective properties are still unknown. In the present study, we aimed to analyze the binding characteristics of sophoridine with alpha-2-macroglobulin (α2M) by spectroscopic and theoretical studies. Then, the cardioprotective effects of sophoridine on myocardial ischemia/reperfusion (MI/R) injury <em>in vitro</em> were investigated using H9c2 cardiomyocytes. The results reveal that one molecule of sophoridine favorably binds to one molecule of α2M dominantly through interaction with hydrophobic amino acid residues (VAL758, PHE735, PHE735, and TRP739). Also, sophoridine leads to partial changes in the structure of this carrier protein in the vicinity of TRP739 residue. Cellular assays exhibit that sophoridine recovered cell viability, membrane leakage, and apoptosis induced by MI/R injury. It was detected that sophoridine could mitigate the oxidative stress and intrinsic apoptosis pathway through regulation of Bax, Bcl-2, and caspase. ELISA analysis also exhibits that sophoridine upregulates phosphorylation of Akt and PI3K in H9c2 cells. Our findings suggest that sophoridine could show favorable plasma protein interaction and promising cardioprotection against MI/R injury mediated by the upregulation of PI3K/AKT signaling pathway.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106014"},"PeriodicalIF":5.3,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinglong Chen , Hongbo Zhu , Haiying Zhang , Tang Zhou , Xingxi Li , Bo Hou , Weiyan Hu , Rongping Zhang
{"title":"Cytotoxic diterpenoids from the roots of Euphorbia jolkinii Boiss against human pancreatic cancer SW1990 cells by regulating the expressions of Bcl-2, Bax, and Caspase-3 proteins","authors":"Xinglong Chen , Hongbo Zhu , Haiying Zhang , Tang Zhou , Xingxi Li , Bo Hou , Weiyan Hu , Rongping Zhang","doi":"10.1016/j.arabjc.2024.106012","DOIUrl":"10.1016/j.arabjc.2024.106012","url":null,"abstract":"<div><div>Sixteen undescribed diterpenoids were identified from <em>Euphorbia jolkinii</em> Boiss, a widespread invasive plant in the grassland ecosystem of subalpine meadows in southwest China, through a combination of spectroscopic data analysis. These included two casbane diterpenoids (<strong>1</strong> and <strong>2</strong>), two <em>ent</em>-atisane diterpenoids (<strong>3</strong> and <strong>4</strong>), and twelve <em>ent</em>-isopimarane diterpenoids (<strong>5</strong>–<strong>16</strong>). All isolates were evaluated the cytotoxicity on pancreatic cancer SW1990 cells in which compounds <strong>1</strong> and <strong>9</strong> exhibited obvious bioactivities against the tumor cells with the IC<sub>50</sub> values of 26.50 ± 6.36 and 21.09 ± 5.98 μM respectively. Moreover, compounds <strong>1</strong> and <strong>9</strong> were found to promote the pre-apoptosis of SW1990 cells and regulate the expressions of Bcl-2, Bax, and Caspase-3 proteins to display anti-tumor abilities. Compounds <strong>1</strong> and <strong>9</strong> were subjected to Bcl-2 protein <em>via</em> molecular ducking to reveal their anti-tumor mechanism further. The druggability prediction showed that they possessed good drug properties with development and utilization scenarios.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106012"},"PeriodicalIF":5.3,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142424807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conessine alleviates PTZ-induced epilepsy in rat model via attenuating neuroinflammation and oxidative stress","authors":"Fang Chen, Tingting Peng, Mengjiao Gou","doi":"10.1016/j.arabjc.2024.106009","DOIUrl":"10.1016/j.arabjc.2024.106009","url":null,"abstract":"<div><div>Epilepsy is a complex neurological disorder which affects the quality life of individual and also hinders the economic status of both the individuals and the country since it requires prolonged medications. The etiology of epilepsy is varied and the neuroinflammation has been considered to be the prime initiator and the stimulator of the disease progression. Therefore anti-inflammatory drugs are suggested to treat seizure and also to prevent epilepsy. The currently available antiepileptic drugs cause’s adverse effects which obstructs the usage of these drugs and also these drugs are not cost effective. Phytochemicals are effective alternative to these drugs and it is prescribed in the traditional medicine. Conessine, a steroidal alkaloid present in bark extracts of Holarrhena sps possess antibiotic, anti-diarrheal, antimalarial and anti-inflammatory properties. We evaluated the antiepileptic potency of conessine in PTZ challenged animal model treated with 10 and 20 mg/kg of conessine respectively. The seizure induction, severity and the behavioral changes were observed in the rats. The impact of conessine on neurochemical signaling in PTZ challenged rats were assessed via quantifying the neurotransmitter and ATPase levels in the brain tissue. Antioxidants and MDA levels were measured to evaluate the antioxidant potency of conessine in epilepsy induced rats. iNOS and nNOS which are inducers of NO during epileptic conditions were analyzed in the test rats. The stimulators and inflammatory cytokines levels were quantified in the brain to analyze the anti-neuroinflammatory efficacy of the conessine in PTZ challenged rats. AKT/mTOR prime signaling proteins in initiation and progression of epilepsy was quantified in the brain tissue of experimental animals. Neurodegeneration inducers cytochrome <em>c</em>, NF-κB, COX-2 and Caspase 3 were quantified to evaluate the ameliorative potency of conessine against PTZ induced neuronal damage. The neuroprotective and antiepileptic potency of conessine was confirmed with the histopathological scoring of brain tissue in PTZ challenged rats. Conessine treatment effectively inhibited the seizure induction and regulated the neurochemical signaling in epileptic induced rats. It also attenuated the neuroinflammation and oxidative stress induction induced by PTZ treatment. The prime signaling proteins nitric oxide synthatase and AKT/mTOR signaling proteins were effectively inhibited by the conessine treatment which eventually prevented the neurodegeneration inducers. Conessine treatment significantly enhanced the levels of Caspase 3. The histopathological analysis confirms the neuroprotective, anti-inflammatory and antiepileptic potency of conessine. Conessine treatment also doesn’t caused any behavioral alterations in the rats hence it is safe and potent alternative for currently available antiepileptic drugs.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106009"},"PeriodicalIF":5.3,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue Meng , Yang Liu , Suyi Liu , Qianqian Zhang , Kunze Du , Omachi Daniel Ogaji , Lirong Wang , Xingyue Jin , Jin Li , Yanxu Chang
{"title":"A review of Viticis Fructus: botany, historical records, phytochemistry, pharmacology, toxicity, quality control, pharmacokinetics and comprehensive applications","authors":"Xue Meng , Yang Liu , Suyi Liu , Qianqian Zhang , Kunze Du , Omachi Daniel Ogaji , Lirong Wang , Xingyue Jin , Jin Li , Yanxu Chang","doi":"10.1016/j.arabjc.2024.106008","DOIUrl":"10.1016/j.arabjc.2024.106008","url":null,"abstract":"<div><h3>Background</h3><div>Viticis Fructus (also known as Manjingzi) has been used in China for more than 2000 years. It is one of the most famous traditional Chinese medicines with the main effect of dispelling wind-heat. In Asian countries, it is used in the treatment of common cold with wind-heat syndrome, swollen gums, migraines, dizziness, <em>etc</em>.</div></div><div><h3>The aim of the review</h3><div>The paper emphasizes on the botany, historical records, phytochemistry, pharmacology, toxicity, quality control, pharmacokinetics and comprehensive applications of Viticis Fructus to furnish with a scientific theoretical reference for its exploration and applications.</div></div><div><h3>Materials and methods</h3><div>Correlative data on Viticis Fructus were obtained from PubMed, ScienceDirect, Web of science, Embase, Scopus, Google Scholar, CNKI, WeiPu, Chinese ancient books and DuXiu academic search. The data collection ended in May 2024.</div></div><div><h3>Results</h3><div>The results showed 324 compounds, including terpenoids, flavonoids, lignans and others, which were isolated and identified from Viticis Fructus. In addition to treating headaches and eye pain, Viticis Fructus also had anti-inflammatory, antiplatelet activation, analgesia, antitumor and antihypertensive effects. In addition, this review summarized the botany, toxicity, counterfeit identification, pharmacokinetics and patent information of Viticis Fructus in detail. The shortcomings and feasible suggestions are put forward, which provide a basis for further research and utilization of Viticis Fructus.</div></div><div><h3>Conclusion</h3><div>Viticis Fructus has been used to remedy common cold with wind-heat syndrome, cephalalgia, ophthalmodynia, dizziness, <em>etc</em>. The pharmacological activities of the main components have been clarified and backed up the traditional applications. However, the botany, processing, pharmacological mechanism, quality control and toxicological studies of Viticis Fructus need to be further improved.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 12","pages":"Article 106008"},"PeriodicalIF":5.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142424808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng Wang , Bingtao Gui , Tianjie Li , Ruiyang Chang , Junxiang Shu , Xiaoqin Deng , Li Chen , Maodan Luo , Bing Jiang , Su Xu , Juan Zhai , Jun Liu , Changsong Zhao
{"title":"U(Ⅵ) sorption by porous sodium zirconium phosphate pellets from aqueous solution","authors":"Cheng Wang , Bingtao Gui , Tianjie Li , Ruiyang Chang , Junxiang Shu , Xiaoqin Deng , Li Chen , Maodan Luo , Bing Jiang , Su Xu , Juan Zhai , Jun Liu , Changsong Zhao","doi":"10.1016/j.arabjc.2024.106007","DOIUrl":"10.1016/j.arabjc.2024.106007","url":null,"abstract":"<div><div>Zirconium phosphate is the first artificially produced layered phosphate that can sorb a variety of nuclides from solutions. Sodium zirconium phosphate (NZP) was a type of α-zirconium phosphate (α-ZrP). The porous sodium zirconium phosphate pellets (p-NZP-P) with a diameter of more than ∼3 mm were prepared and used for uranium sorption. The p-NZP-P could be immersed in solutions for more than 5 days without dissolving and structurally collapsing. The sorption properties of U(Ⅵ) on p-NZP-P in solutions were investigated by both static and dynamic sorption tests. Synthetic p-NZP-P was analyzed in detail using various characterizations to investigate their character and structural changes. In the static sorption experiment, the equilibrium sorption capacity reached the 77.5 ± 1.5 mg·g<sup>−1</sup> when the initial concentration of U(Ⅵ) was 100 mg/L, pH<sub>initial</sub> = 4.5, <em>T</em> = 25 ℃. Uranium sorption increased by ∼69 % and ∼215 %, respectively, when the initial uranium concentration was increased from 100 to 300 mg·L<sup>−1</sup> and the temperature was increased from 15 to 55 °C. Furthermore, uranium sorption increased by ∼541 % when the initial pH increased from 2.5 to 4.5, while it decreased by ∼39 % when the initial pH increased from 4.5 to 7.0. The sorption data corresponded to the pseudo-second-order kinetic model and the Langmuir isotherm model, as well as the theoretically predicted value of sorption capacity (∼199.9 mg·g<sup>−1</sup>). The results of the dynamic sorption experiment showed that decreasing the quality, increasing the flow rate and the initial U(Ⅵ) concentration would shorten the breakthrough time. The dynamic sorption data agreed well with the Thomas model. The characterization confirmed the porous properties, while the U(Ⅵ) sorption mechanisms relate to –OH coordination and ion exchange. A radioactive rare earth wastewater treatment test suggested that p-NZP-P could be the potential uranium sorbent due to its good stability and efficiency. This paper opened opportunities for the development of practical materials for treating radioactive wastewater in the application of actual scenarios.</div></div>","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"17 11","pages":"Article 106007"},"PeriodicalIF":5.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}