Arabian Journal of Chemistry最新文献

{"title":"Macroporous-resin decolorization alters structure and bioactivity of Scutellaria baicalensis polysaccharides","authors":"Heping Hui, Haoji Mao, Bowen Wang, Xinyu Tao","doi":"10.25259/ajc_1081_2025","DOIUrl":"https://doi.org/10.25259/ajc_1081_2025","url":null,"abstract":"The decolorization process of Scutellaria baicalensis polysaccharide (SBP) by macroporous resin was optimized through response surface methodology. The crude SBP (SBP-C) and decolorized SBP (SBP-D) were then structurally characterized by UV, high performance liquid chromatography (HPLC), gel-permeation chromatography (GPC), Fourier transform infrared spectrometer (FTIR), NMR, scanning electron microscopy (SEM), zeta potential, particle size, and thermogravimetric analysis. Their functional properties were evaluated in vitro and by fluorescence spectroscopy, with correlation analysis used to reveal the structure-activity relationship. The results showed that HPD-600 resin exhibited the best decolorization effect under optimal conditions: temperature 38°C, resin dosage 8 g, pH 3.4, and time 2.9 h. After decolorization, the total sugar content and the levels of glucose/arabinose/galactose increased significantly ( p < 0.05), while protein content decreased ( p < 0.05). Low molecular weight polysaccharides (3600–3300 g/mol) were retained, showing a predominantly multi-helical α / β -(1→4) structure with good thermal stability. Particle size and zeta potential decreased by 32.26% and 52.36%, respectively, and the microstructure transitioned into looser sheet-like helical stacks with elevated methyl-esterified galacturonic acid. These alterations improved water stability, moisture absorption, water/oil holding capacity, good emulsifying ability, and enhanced antioxidant and hypoglycemic activities. The IC₅₀ values for scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals and for inhibiting α -amylase and α -glucosidase were 0.19, 0.25, 0.73, and 0.24 mg/mL, respectively. Fluorescence spectroscopy indicated that SBP non-competitively inhibited α -glucosidase and α -amylase via static quenching, with SBP-D showing enhanced efficacy. The preferred decolorization process serves as a promising purification strategy to obtain SBP with desirable functional properties, making it a potential candidate ingredient for functional foods, nutritional products, and other health-related applications.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"0 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://arabjchem.org/content/184/2026/0/1/pdf/AJC_1081_2025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148861304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling the antimicrobial and antioxidant potential in Shidiaolan, a Hmong medicinal plant: A multi-technology strategy integrating UPLC fingerprinting, chemometrics, molecular docking, and response surface optimization","authors":"Mingyu Yang, Qihua Yu, Yitang Xu, Xing Jiang, Xiang Lu, Xiaoxia Wan, Hailong Qin, Liyong Yang, Mengyu Li, Ye Yang","doi":"10.25259/ajc_454_2025","DOIUrl":"https://doi.org/10.25259/ajc_454_2025","url":null,"abstract":"Shidiaolan (SDL) is a medicinal plant traditionally used in the Hmong region for its antimicrobial and antioxidant properties, though its active constituents remain undefined. Ultra performance liquid chromatography (UPLC) fingerprinting results indicated that 28 SDL batches exhibited similar compositional profiles and stable peak clusters. SDL exhibited minimum inhibitory concentration (MIC) values of 12.5-400 mg mL -1 against Staphylococcus capitatus (SC) and 6.25-400 mg mL -1 against Candida albicans (CA), with corresponding minimum bactericidal concentration (MBC) values of 400 mg mL -1 and 200 mg mL -1 , respectively. The batch inhibition results showed that S1, S6, and S10 had no inhibitory effect on SC, and S10 had no inhibitory effect on CA, while the remaining batches exhibited inhibitory effects against both bacterial strains. Spectral potency analysis identified bacteriostatic active ingredient groups in SC as F2, F8, F10, F12, and F13, and in CA as F8 and F13. Molecular docking results demonstrated low binding energy between the drug moiety and the protein, generating five interaction forces that indicate strong affinity and a stable binding conformation. The active ingredient exerted its inhibitory effect through various amino acid residues such as valine, asparagine, and aspartic acid. The antibacterial active ingredients have been classified into flavonoid and polyphenol components. After optimizing the extraction process for both components, the total flavonoid content (TFC) extracted from SDL was 15.968 mg g -1 , and the total polyphenol content (TPC) was 15.867 mg g -1 . Furthermore, batch extracts of both TFC and TPC demonstrated antioxidant capacity in 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2, 2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"0 1","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148305634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of compound enzyme-assisted ultrasound extraction for <i>Polygonatum sibiricum</i> polysaccharides with characterization and bioactivity evaluation","authors":"Lei Peng, Jie Su, Yigong Chen, Hengpu Zhou, S. H. Chen, Guiyuan Lv","doi":"10.25259/ajc_1134_2025","DOIUrl":"https://doi.org/10.25259/ajc_1134_2025","url":null,"abstract":"Polygonatum sibiricum (PS) is a medicinal plant with significant therapeutic value, and Polygonatum sibiricum polysaccharide (PSP) represent its core bioactive components. We developed an ultrasound-assisted mixed-enzyme extraction process for PSP preparation and optimized the parameters. Subsequently, PSP was characterized to determine its microstructure, functional groups, and crystalline structure. Its monosaccharide composition and molecular weight were also determined. Finally, oligoasthenospermia (OAS) mouse models were established to evaluate therapeutic effects. The results demonstrated optimal extraction conditions: 105 min extraction time, 61°C temperature, 1:25 material-liquid ratio, and an enzyme dosage of 3080 U g -1 of dry material. The PSP yield reached 28.26%. PSP presented as amorphous flakes with characteristic polysaccharide functional groups, containing arabinose (1.7 μg mg -1 ), galactose (7.61 μg mg -1 ), glucose (571.47 μg mg -1 ), mannose (17.4 μg mg -1 ), and fructose (25.83 μg mg -1 ), with a molecular weight of 25,444 Da (within the medium molecular weight range of 10-100 kDa). PSP significantly enhanced sperm quality in OAS mice and upregulated CYP17A1 and HSD3β2 expression ( p &lt;0.05). This indicates PSP promotes testosterone synthesis by regulating key steroidogenic enzymes. Therefore, the established process enables the large-scale production of PSP, which demonstrates the potential to treat OAS by modulating molecular mechanisms, laying the foundation for the development of biological products for reproductive health.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"11342025-11342025"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in chemical constituents and bioactivities of essential oils within <i>Elatostema stewardii</i> Merr. revealed by GC-MS-based metabolomics","authors":"Fengke Lin, Zihao Liu, Ying Liu, Meiyi Niu, Rui Zhao, Zhongxin Duan, Yunan Hu, Binsheng Luo","doi":"10.25259/ajc_712_2025","DOIUrl":"https://doi.org/10.25259/ajc_712_2025","url":null,"abstract":"Elatostema stewardii Merr., an endemic species in China, is valued for its medicinal and food uses, yet its chemical compositions and biological activities remain unexplored. This study aims to analyze the essential oils (EOs) obtained from different plant parts (leaves, stems, and roots) of E. stewardii by gas chromatography-mass spectrometry (GC-MS)-based metabolomics. Collectively, 96 EO constituents were identified, primarily consisting of fatty acids (trace-61.56%), diterpenes (3.47-32.39%), alkanes (7.79-16.32%), and ketones (1.46-12.00%). Major constituents included n -hexadecanoic acid (trace-60.58%), 2-methyloctadecane (4.63-12.31%), phytol (0.19-12.00%), and 6,10,14-trimethyl-2-pentadecanone (1.39-9.92%). Multivariate analyses principal component analysis (PCA) and partial least squares-discriminant component analysis (PLS-DA) revealed significant EO chemical variations in plant parts, identifying 15 key differential constituents such as n -hexadecanoic acid, 3,5,11,15-tetramethyl-1-hexadecen-3-ol, and linoleic acid. Bioactivity assays demonstrated significant differences among the EOs, with the leaf-derived EO exhibiting the strongest cytotoxicity (IC 50 : 36.58-69.23 μg mL -1 ), anti-inflammatory effects (IC 50 : 47.03 μg mL -1 for NO inhibition), and antioxidant capacity (IC 50 : 0.08, 0.33 mg mL -1 for ABTS, DPPH scavenging, respectively; FRAP: 2.95 mmol Fe 2+ /mL). Correlation analysis showed that compounds like β -ionone-5,6-epoxide and neophytadiene were positively associated with these bioactivities. These findings highlight substantial chemical and bioactivity differences among E. stewardii EOs, identifying the leaf EO as a promising pharmaceutical candidate and demonstrating the effectiveness of GC-MS-based metabolomics in investigating Elatostema EOs.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"0 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://arabjchem.org/content/184/2026/0/1/pdf/AJC_712_2025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient protection of sintered NdFeB enabled by incorporation of polyethyleneimine-grafted graphene oxide into silane films","authors":"Tao Zhu, Fan Zhang, Li Jiang, Siyu Chen, Rui Wang, Jiao Liu, Yumeng Yang, Guoying Wei, Y. Chen","doi":"10.25259/ajc_606_2025","DOIUrl":"https://doi.org/10.25259/ajc_606_2025","url":null,"abstract":"Polyethyleneimine modified graphene oxide (PEI-GO) was designed as an additive and subsequently co-deposited with bis-silane on sintered neodymium-iron-boron (NdFeB) magnets to prepare hydrophobic and anti-corrosive PEI-GO/silane composite films via an electrochemically assisted sol-gel method. Structural and compositional characterizations were carried out using fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscope (SEM), and Raman spectroscopy. Results confirmed successful grafting of PEI onto GO. Silane coupling agents linked to the PEI-GO additives, as well as the sintered NdFeB substrate, through covalent bonds. The corrosion resistance of the fabricated composite films in a 3.5 wt.% NaCl solution was assessed through electrochemical impedance spectroscopy and potentiodynamic polarization tests. The corrosion current density of PEI-GO/silane film under optimal deposition conditions was 8.365×10 -8 A·cm -2 , which is two orders of magnitude smaller than that of the neat silane film. Enhanced anti-corrosion performance of PEI-GO/silane composite film can be primarily attributed to the grafted PEI, which significantly enhanced the barrier effect of GO by improving its dispersion within the sol-gel system. Meanwhile, the co-deposited PEI-GO remarkably reinforced the structural integrity and compactness of the composite film. Furthermore, the composite coating exhibits outstanding hydrophobicity, with a water contact angle reaching 148.5°, and simultaneously maintains the magnetic properties of the sintered NdFeB magnets without detectable compromise.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"6062025-6062025"},"PeriodicalIF":0.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://arabjchem.org/content/184/2026/19/3/pdf/AJC-19-6062025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147908363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical design and characterization of fluoropolymer-silica nanocomposite superhydrophobic coating for durable and self-cleaning photovoltaic cells","authors":"Ahmed A. Bakhsh","doi":"10.25259/ajc_310_2025","DOIUrl":"https://doi.org/10.25259/ajc_310_2025","url":null,"abstract":"Dust accumulation on photovoltaic (PV) solar panels significantly reduces the efficiency of energy conversion. Thus, innovative surface modifications are needed to mitigate soiling and enhance durability. This study presents the development of a robust polymer-based superhydrophobic coating designed to minimize dust adhesion while maintaining PV performance. The coating formulation integrates polyvinylidene fluoride (PVDF) as a hydrophobic matrix with superhydrophobic silica nanoparticles (SiO₂) to achieve optimal surface properties. The optimized composition, consisting of 2 wt% PVDF and 35 wt% SiO₂, exhibited a high-water contact angle of 155.8°, confirming its superior hydrophobicity. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses revealed a rough hierarchical structure, which is a key factor in achieving superhydrophobicity. Mechanical durability was validated through peel tests, demonstrating strong adhesion and long-term stability. PV performance analysis of silicon solar cells coated with the developed material showed no reduction in power output, confirming its compatibility with solar energy applications. These findings highlight the potential of the proposed superhydrophobic coating to enhance the efficiency and longevity of PV panels in real-world conditions, addressing critical challenges in solar energy deployment.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"3102025-3102025"},"PeriodicalIF":0.0,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://arabjchem.org/content/184/2026/0/1/pdf/AJC_310_2025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147921725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aptamer functionalized sheet-like α-Fe ₂ O ₃ /Fe ₃ O ₄ magnetic nanocomposite-based electrochemical nano-biosensor for the accurate detection of nucleolin","authors":"Min Sun, Boyi Jiang, Jiawei Wang, Zhou Wang, Xinyan Gao, X.Y. Yi","doi":"10.25259/ajc_455_2025","DOIUrl":"https://doi.org/10.25259/ajc_455_2025","url":null,"abstract":"The detection of tumor biomarkers is critical in diagnostics, prevention, and therapeutics. As a significant biomarker of renal carcinoma, breast cancer, lymphocytic leukemia, and so on, the accurate detection of nucleolin (NCL) is of great significance in clinical examination. Due to the inherent limitations of complex operation, time consumption, and low sensitivity of traditional methods, there is an urgent need to develop rapid, sensitive, and simple detection strategies. In this project, α-Fe 2 O 3 /Fe 3 O 4 @Au magnetic nanocomposites (MNCs) were fabricated via a hydrothermal and calcination process with the reduction of chloroauric acid. Further, depending on the facile combination of Au and sulfur, α-Fe 2 O 3 /Fe 3 O 4 @Au-Apt/BSA probes were constructed. Subsequently, the aptamer on the probes could specifically recognize and bind to NCL through its high affinity for the target. The magnetic probes, after capturing the target, could self-assemble on the surface of a magnetic glassy carbon electrode (MGCE) under magnetic induction for electrochemical detection, which improved the operability and avoided possible bio-coating contamination. The nano-biosensors revealed favorable linear relationship (R 2 = 0.995) of the current signal and NCL concentration within 0.1 pg/mL-10 ng/mL, a low limit of detection (LOD) of 0.24 pg/mL, high stability with RSD of 1.04%, satisfactory guarantee period of 20 days, strong specificity, and favorable recoveries in human serum samples (98.09-105.65%), which outperformed conventional EC methods, suggesting the promising prospect of nano-biosensors for NCL detection in clinical examination.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"4552025-4552025"},"PeriodicalIF":0.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147919040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and evaluation of thiadiazole thioether analogs for hedgehog signaling pathway inhibition and malignant biological behavior against medulloblastoma cells","authors":"Hongjuan Li, Shu Han, Y. WANG, Miao Wang, Bicheng Yang, Xinyue Shang, Zhiping Xu, Fangliang Yang, Chiyu Sun","doi":"10.25259/ajc_394_2025","DOIUrl":"https://doi.org/10.25259/ajc_394_2025","url":null,"abstract":"Medulloblastoma (MB), a prevalent pediatric malignant neoplasm that arises in the cerebellum. It demonstrates a pathogenesis fundamentally linked to dysregulated Hedgehog (HH) pathway activation. Smoothened (SMO), a core component of the Hh pathway, undergoes abnormal activation that triggers hypertranscription of the downstream target gene GLI1 , resulting in sustained activation of the HH pathway and subsequently accelerating tumor cell proliferation and invasion. Unfortunately, vismodegib, approved by the FDA, has encountered the challenge of drug resistance in MB treatment. Therefore, developing novel HH pathway inhibitors to precisely block this abnormal signaling conduction has become a critical issue that the scientific community urgently needs to address, holding great significance for the innovation of treatment strategies for MB. This study is dedicated to designing, synthesizing, and evaluating a series of HH pathway inhibitors targeting SMO, based on the thiadiazole thioether scaffold. Through rigorous GLI luciferase reporter gene assay screening, we have successfully identified a promising analog, 2-((2-methoxyphenyl)thio)-5-(pyridin-4-yl)-1,3,4-thiadiazole (WMC03). This compound exhibits a competitive action similar to cyclopamine at the binding site of the SMO protein, reducing cilium formation by binding to SMO, and thereby inhibiting the activation of the HH pathway. Molecular modeling approaches have provided deeper insights into the interaction mechanism between WMC03 and the SMO protein, shedding light on the collaborative contributions of hydrogen bonding, hydrophobic interactions, and electrostatic forces. Notably, WMC03 demonstrated a robust ability to suppress GLI1 expression, exerting its inhibitory effects at both the transcriptional and translational stages. This suppression subsequently led to the effective inhibition of Daoy cell proliferation and migration, ultimately triggering apoptosis in these cells. These findings not only emphasize the remarkable efficacy of WMC03 in MB cells but also provide new ideas and approaches for the development of efficient and specific Hh pathway inhibitors for the clinical treatment of MB.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"3942025-3942025"},"PeriodicalIF":0.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147914904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controlled synthesis of hexagonal MgAl-layered double hydroxide nanoplates as potential carriers for controlled drug delivery","authors":"Xiaoli Li, Guangshuo Wang, Yao Lu, Fengtian Shi, Yingying Ma, Dong Li","doi":"10.25259/ajc_719_2025","DOIUrl":"https://doi.org/10.25259/ajc_719_2025","url":null,"abstract":"Controlled drug delivery has demonstrated its great potential to alleviate the unpleasant side effects triggered by chemotherapeutic drugs through improving treatment efficacy in cancer cells while decreasing the adverse effects on normal cells. Herein, hexagonal MgAl-layered double hydroxide (Mg-Al LDH) nanoplates were fabricated by a facile hydrothermal strategy, which were developed as a promising pH-responsive drug delivery system for cancer treatment. The MgAl-LDH nanoplates possessed unique features including well-defined hexagonal morphology, uniform particle size, rough surface, typical mesoporous structure, and high specific surface area. The MgAl-LDH nanoplates exhibited a high drug loading capability of 0.36 mg/mg using non-anionic doxorubicin hydrochloride (DOX) as a classical anticancer model drug. The loaded DOX displayed a sustained and pH-controlled release characteristic with sufficient release of 91.4% and 69.9% under acidic pH values (4.0, 5.5) and suppressed release of 37.8% at a neutral pH level (7.4) after 48 h of release. Furthermore, the developed MgAl-LDH nanoplates displayed good biocompatibility without any obvious cytotoxicity to human breast cancer cells (MCF-7), and DOX-loaded MgAl-LDH exerted the effects of significant suppression of cell proliferation and induction of apoptosis in regions of high concentration.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"7192025-7192025"},"PeriodicalIF":0.0,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://arabjchem.org/content/184/2025/0/1/pdf/AJC_719_2025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147912297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and scale inhibition performance of glucose-modified polyaspartic acid as an efficient scale inhibitor","authors":"Ying Qu, Zhiming Fan, Yanan Li, Ying Xu, Yonghong Cai, Linlin Zhao, Zhihua Wang, Yuxia Wang","doi":"10.25259/ajc_213_2025","DOIUrl":"https://doi.org/10.25259/ajc_213_2025","url":null,"abstract":"The grafting of gluconic acid structural fragments onto polyaspartic acid (PASP) was undertaken to synthesize polyaspartic acid derivatives (PASP/DGL/ED). We used two methods to study the structures of the samples: Fourier transform infrared (FTIR) and nuclear magnetic resonance 1 H (NMR). Furthermore, the scale inhibition, corrosion inhibition, and antimicrobial properties of PASP/DGL/ED were evaluated. The inhibitory effects of PASP/DGL/ED on CaCO 3 , CaSO 4 , and Ca 3 (PO 4 ) 2 scaling were investigated by scanning electron microscopy (SEM) and X-ray diffractometry (XRD). At a certain concentration, PASP/DGL/ED demonstrated significant inhibitory effects, with nearly 80% inhibition of CaCO 3 scale at 30 mg/L, 100% inhibition of CaSO 4 scale at 5 mg/L, and 100% inhibition of Ca 3 (PO 4 ) 2 scale at 11 mg/L. These results indicate that PASP/DGL/ED significantly outperforms traditional scale inhibitors. In addition, the corrosion inhibition efficiency of PASP/DGL/ED on carbon steel was found to exceed 60% at 30 mg/L, and it was effective in inhibiting E. coli . And the biodegradation rate of PASP/DGL/ED was 95.27% at day 28. Molecular dynamics simulations and quantum chemical calculations were conducted to determine the inhibitory mechanism of PASP/DGL/ED. The multifunctional water treatment agent PASP/DGL/ED integrates the functions of scale inhibition, antibacterial, and corrosion inhibition, and its potential application in the industrial field lays a solid foundation.","PeriodicalId":249,"journal":{"name":"Arabian Journal of Chemistry","volume":"19 1","pages":"2132025-2132025"},"PeriodicalIF":0.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}