中华预防医学杂志最新文献

{"title":"[Trend and quantitative analysis of disease mortality in China from 1990 to 2021].","authors":"K Sun, L Chen, J S Wang, Y J Han, X F Luo","doi":"10.3760/cma.j.cn112150-20240903-00703","DOIUrl":"10.3760/cma.j.cn112150-20240903-00703","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the long-term trends in cause-specific mortality across different sexes and age groups in China from 1990 to 2021, and quantitatively assess the impact of population aging on cause-specific deaths by sex. <b>Methods:</b> Based on data from the Global Burden of Disease Study 2021, this study extracted the number of deaths, crude mortality rates and age-standardized mortality rates (ASMRs) for all causes, Level 1 causes (communicable, maternal, neonatal, and nutritional diseases; non-communicable diseases; injuries) and Level 3 causes in China from 1990 to 2021, stratified by sex and age group. This study analyzed the current situation and long-term trends in mortality in China, applying decomposition analysis to quantify the impact of population aging on the number of deaths. <b>Results:</b> In 2021, the ASMRs of all-cause death and the three primary causes of death in Level 1 in China were 644.68, 26.59, 575.55, and 41.82 per 100 000, respectively. The ASMRs of the three primary causes continued to decline, with the smallest decrease observed in non-communicable diseases [EAPC=-1.79%, 95%<i>CI</i> (-1.92%, -1.66%)] and the largest in communicable, maternal, neonatal, and nutritional diseases (CMNND) [EAPC=-5.86%, 95%<i>CI</i> (-6.06%, -5.65%)]. The ASMRs were higher in males than females, with a smaller decline. Mortality was higher in the elderly. CMNND deaths mainly occurred in children under 5 and the elderly; non-communicable disease deaths were concentrated in the elderly; injury deaths were relatively evenly distributed across age groups. The proportion of CMNND deaths decreased annually, while the proportion of non-communicable disease deaths increased. From 1990 to 2021, population aging contributed to an increase of 8.11 million all-cause deaths, 167 464.42 CMNND deaths, 7.74 million non-communicable diseases deaths, and 196 287.78 injury deaths. The impact of population aging differed by sex and disease, with male and female aging-related deaths increasing by 4.47 million and 3.70 million, respectively. Compared to 1990, the age-specific mortality rate contributions in 2021 were -72.82% for males and -93.87% for females, with variations by sex and disease. <b>Conclusion:</b> The composition of disease-related deaths in China has changed notably. Population aging is linked to the sharp rise in deaths, with varying impacts across sexes and diseases. Reducing disease mortality can help lessen the negative effects of population aging.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1232-1238"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Adverse maternal and infant health effects caused by barium exposure during pregnancy].","authors":"X Y Li, J Tong, F B Tao","doi":"10.3760/cma.j.cn112150-20240813-00653","DOIUrl":"10.3760/cma.j.cn112150-20240813-00653","url":null,"abstract":"<p><p>As a common environmental chemical with a wide range of uses and diverse exposure pathways, barium poses potential threats to human health. Exposure to barium during pregnancy, in particular, has been found to have adverse effects on maternal and infant health and has become a major public health concern. Based on existing research findings, this article provides a comprehensive analysis of the sources of barium exposure, the association between gestational barium exposure and pregnancy complications or adverse pregnancy outcomes, its impact on birth outcomes and growth and development among children, and the possible biological mechanisms. The aim is to provide theoretical support and references needed to formulate effective public health strategies that mitigate the harm caused by barium exposure to maternal and infant health.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1305-1310"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Survival analysis in hepatitis C cases aged ≥18 years in Yuxi City from 2005 to 2023].","authors":"Y Luo, S F Li, W B Dong, J X Zhao, Z Li, Y F Zhu, L Y Chen, Y Cai, X C Liu, R S Yang","doi":"10.3760/cma.j.cn112150-20241118-00916","DOIUrl":"10.3760/cma.j.cn112150-20241118-00916","url":null,"abstract":"<p><p>To analyze all-cause mortality among hepatitis C cases aged ≥18 years in Yuxi City from 2005 to 2023 and explore the interactions of factors influencing survival time. Baseline and follow-up data for hepatitis C cases reported during this period were extracted from the Chinese National Notifiable Disease Reporting System. Survival time and related factors were assessed using the Cox proportional hazards model. Kaplan-Meier cumulative mortality risk curves were generated for treated and untreated hepatitis C cases, and interactions among subgroups of various influencing factors were examined. A total of 5 110 hepatitis C cases aged ≥18 years were reported from 2005 to 2023, encompassing 35 349.25 person-years of observation with the follow-up time duration <i>M</i> (<i>Q</i>₁, <i>Q</i>₃) was 6.17 (2.33, 11.08) person-years. There were 763 all-cause deaths, corresponding to a mortality density of 2.16 per 100 person-years. Survival analysis showed a statistically significant difference in cumulative mortality between the treated and untreated groups (Log-rank <i>χ</i>²=122.033, <i>P</i><0.001), with a lower risk of death observed among treated patients. Additive model analysis showed that there was a synergistic interaction between treatment status and age group, with relative excess of interaction, attributable proportions of interaction, and synergy index of 6.16 (95<i>%CI</i>: 2.70-9.61), 1.83 (95<i>%CI</i>: 1.46-2.30), and 0.42 (95<i>%CI</i>: 0.31-0.53), respectively; and between treatment status and gender. There was a synergistic interaction between treatment status and sex, with relative excess of interaction, attributable proportions of interaction, and synergy index of 2.63 (95<i>%CI</i>: 1.14-4.13), 1.56 (95<i>%CI</i>: 1.19-2.06), and 0.32 (95<i>%CI</i>: 0.17-0.46), respectively. The cause of death composition were 38.53% (249 cases) attributed to hepatitis C-related causes.The leading non-hepatitis C-related causes of death were cardiovascular and cerebrovascular diseases, pulmonary diseases, malignancies, drug overdose, and injuries. In conclusion, hepatitis C cases ≥18 years of age in Yuxi City had a lower cumulative mortality rate when treated than when untreated. Treatment status interacted with age and gender on patient survival, respectively. Changes in patients with concomitant cardiovascular diseases, pulmonary diseases and malignancies should be focused.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1217-1223"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Epidemiological and molecular traceability analysis of the first cluster outbreak of D8 genotype measles in Henan Province].","authors":"X X Zhang, B H Du, D X Feng, W H Wang, J Li, L L Liu, H Zi, Q H Wan, S T Zhao, X L Wang, X B Wu, Y H Guo, Y Y Zhang, D Y Zhao","doi":"10.3760/cma.j.cn112150-20250415-00314","DOIUrl":"10.3760/cma.j.cn112150-20250415-00314","url":null,"abstract":"<p><p>In February 2025, a local cluster outbreak caused by the D8 genotype Measles virus (MV) was first discovered in Henan Province. Epidemiological investigations and laboratory testing were conducted, including the collection of serum and throat swabs for MV IgM antibody and nucleic acid detection, virus isolation and genetic homology analysis. Measures such as close contact tracing, vaccination rate assessment and supplementary immunization activities were implemented, successfully preventing broader community transmission. A total of three cases were reported during the outbreak, including one imported-related adolescent and two secondary local adult cases. All cases presented with typical symptoms such as fever and rash. Both adult cases were complicated by pneumonia, with one case developing into severe pneumonia. MV genotyping showed that the two secondary cases were both the D8 genotype, with the viral sequences being completely homologous to the Kazakhstan strain. Among the close contacts, 98.2% were adults, and 142 individuals received emergency vaccination.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1294-1298"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Knowledge, attitude and practice of salt reduction and hypertension status and related factors among restaurant practitioners in Beijing City].","authors":"J H Huang, J J Ren, R Zheng, F Xu, Y Qu, J L Duan, Y Han","doi":"10.3760/cma.j.cn112150-20250125-00075","DOIUrl":"10.3760/cma.j.cn112150-20250125-00075","url":null,"abstract":"<p><p>A convenience sampling method was employed to recruit 445 food service employees from 67 Chinese restaurants across all 16 administrative districts of Beijing City from August to December in 2022. A questionnaire survey was conducted to assess their knowledge, attitudes, and behaviors regarding salt reduction and hypertension. The results revealed that awareness was highest for the statement \"Hypertensive patients should reduce salt intake\" (88.3%), while awareness of \"China's diagnostic criteria for hypertension\" was the lowest (23.8%). Positive attitude endorsement rates were 96.0% for willingness to reduce salt, 95.3% for perceived self-efficacy in salt reduction, and 93.0% for agreement with a low-salt diet. Regarding behaviors, the rates of actively reducing salt when ordering takeout or dining out, using low-sodium salt, and using salt-reducing spoons were 73.7%, 45.4%, and 55.5%, respectively. The overall compliance rate for salt-reduction related behaviors was 73.9%. Multivariable logistic regression analysis demonstrated that: compared to the 18-29 age group, employees aged 30-39 (<i>OR</i>=2.19, 95%<i>CI</i>: 1.16-4.14), 40-49 (<i>OR</i>=3.36, 95%<i>CI</i>: 1.52-7.42), and 50-59 (<i>OR</i>=3.25, 95%<i>CI</i>: 1.25-8.50) were significantly more likely to achieve compliance with salt-reduction behaviors; chefs were significantly more likely to achieve behavioral compliance compared to managerial staff (<i>OR</i>=2.08, 95%<i>CI</i>: 1.08-3.98); employees in catering with adequate knowledge about salt reduction and hypertension were significantly more likely to exhibit behavioral compliance compared to those with inadequate knowledge (<i>OR</i>=3.32, 95%<i>CI</i>: 1.83-5.92); employees in catering with positive attitudes towards salt reduction were significantly more likely to achieve behavioral compliance compared to those with negative attitudes (<i>OR=</i>5.81, 95%<i>CI</i>: 2.05-16.43). In conclusion, food service employees in Beijing exhibit insufficient knowledge about salt intake and hypertension. While they demonstrate strong willingness to reduce salt, this does not consistently translate into action. Compliance with salt-reduction behaviors is influenced by age, education level, and job position. There is an urgent need to strengthen the dissemination of knowledge regarding high salt intake and hypertension and to implement personalized interventions targeting salt-reduction behaviors and skills.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1299-1304"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on key issues in prevention and control of human respiratory syncytial virus infection in the older population in China].","authors":"","doi":"10.3760/cma.j.cn112150-20250506-00391","DOIUrl":"10.3760/cma.j.cn112150-20250506-00391","url":null,"abstract":"<p><p>Human respiratory syncytial virus (HRSV) is one of the most common pathogens causing acute lower respiratory infections in children globally and poses a significant burden of severe respiratory disease among elderly and adults with underlying conditions. Several immunization products are currently available to prevent severe HRSV disease in infants and elderly adults. To guide and standardize HRSV control and prevention among the elderly population, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College established a multidisciplinary expert panel to develop this expert consensus. Based on domestic and global research progress, evidence, and prevention/control experience, this expert consensus focuses on key technical issues including HRSV disease burden, surveillance, prevention/control strategies, vaccine application and recommendations. The consensus particularly emphasizes identifying critical technical questions from a policy perspective and consolidating expert consensus, aiming to provide healthcare professionals with reference for HRSV prevention and control in elderly populations.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 ","pages":"1183-1195"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The investigation of DNA tetrahedral nanoparticles as mucosal vaccine carriers and adjuvants].","authors":"X T Chen, J Yang, H L Liu, L L Wang","doi":"10.3760/cma.j.cn112150-20240814-00657","DOIUrl":"10.3760/cma.j.cn112150-20240814-00657","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the feasibility of DNA tetrahedral framework (DNA-TH) as a carrier and adjuvant for mucosal vaccines, using streptavidin (SA) as a model antigen. <b>Methods:</b> DNA-TH was designed using software, integrating the adjuvant CpG sequence into its structure. After in vitro synthesis, it was conjugated with SA to form SA-DNA-TH nanoparticles. In vitro experiments: free SA and the two-dimensional structure SA-CpG (SA directly conjugated to CpG) were used as controls. The uptake efficiency of SA-DNA-TH by mouse primary macrophages and its ability to activate antigen-presenting cells (APCs) were evaluated. In vivo experiments: following submucosal oral injection, a mixture of free SA and free CpG (mixed group) was used as a control. The distribution of SA within mouse lymph nodes was observed using immunofluorescence staining. Levels of SA-specific antibodies (serum IgG, IgM; salivary sIgA) in serum and saliva were measured to assess humoral and mucosal immune responses. <b>Results:</b> Native polyacrylamide gel electrophoresis confirmed the successful synthesis of DNA-TH and SA-DNA-TH. In vitro experiments: SA-DNA-TH was rapidly taken up by primary macrophages. Its uptake rate (92.65%±4.43%) was significantly higher than that of the SA-CpG group (25.37%±3.56%) and the free SA group (1.80%±1.02%; both <i>P</i><0.01). SA-DNA-TH also induced significantly stronger APC activation (OD value fold increase: 3.60±0.32) compared to the free SA group (1.13±0.10) and the SA-CpG group (1.21±0.02; both <i>P</i><0.01). In vivo experiments: lymph node distribution analysis revealed overlapping signals of SA with subcapsular sinus macrophages (SCSMs) and dendritic cells (DCs) in the SA-DNA-TH group, whereas SA signals appeared dispersed and non-overlapping with APCs in the mixed group. Regarding immunogenicity, both serum anti-SA antibody (IgG+IgM) titers and salivary anti-SA sIgA antibody titers induced by SA-DNA-TH were significantly higher than those in the mixed group and the blank control group (both <i>P</i><0.05). <b>Conclusion:</b> DNA-TH effectively delivers the model antigen SA to antigen-presenting cells, significantly induces the production of serum-specific antibodies, and activates mucosal immune responses. It demonstrates potential as a carrier and adjuvant for developing mucosal vaccines.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1270-1278"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preliminary study on the biological role of EF-hand domain-containing protein 2 in hepatocellular carcinoma].","authors":"Y M Zhang, X Li, X X Jia, J Z Liu, W Q Li, J F Xuan, S Y Feng, Z H Sun, W Y Zhang","doi":"10.3760/cma.j.cn112150-20250312-00198","DOIUrl":"10.3760/cma.j.cn112150-20250312-00198","url":null,"abstract":"<p><p>This study investigates the expression pattern and functional significance of EF-hand domain-containing protein 2 (EFHD2) in hepatocellular carcinoma (HCC), with particular focus on its regulatory effects on tumor proliferation, migration, and invasion. Cellular experimental study was completed from June 2024 to January 2025 in the Basic Laboratory of the General Hospital of Southern Theater Command. TCGA database to determine EFHD2 expression and its clinicopathological correlations. GSCA database to assess methylation patterns and immune infiltration. Model of transient overexpression and knockdown of EFHD2 was constructed in hepatocellular carcinoma cells Hep3B, then RT-qPCR and Western blot were applied to verify the transfection efficiency. CCK-8 and colony formation assays for proliferation assessment, Transwell chambers for migration/invasion quantification. Protein-protein interaction networks were constructed via STRING, followed by GO/KEGG enrichment analysis. Statistical analysis was performed using the two independent samples <i>t</i>-test. The results showed that EFHD2 demonstrated significant upregulation in HCC tissues versus normal controls (<i>P</i><0.05). Elevated EFHD2 expression correlated with advanced clinical stage (<i>P</i><0.05) and poor differentiation (<i>P</i><0.05). In the CCK-8 assay, the EFHD2 overexpression group demonstrated significantly higher cell viability than the control group, as evidenced by 450 nm relative absorbance values on Day 1 (0.529±0.019 <i>vs.</i> 0.515±0.016, <i>F</i>=0.041, <i>P</i>=0.320), Day 2 (1.356±0.019 <i>vs.</i> 1.094±0.042, <i>F</i>=3.833, <i>P</i><0.001), Day 3 (2.817±0.049 <i>vs.</i> 2.143±0.124, <i>F</i>=3.833, <i>P</i><0.001), and Day 4 (3.848±0.015 <i>vs.</i> 3.430±0.021, <i>F</i>=0.469, <i>P</i><0.001). The EFHD2 knockdown group showed reduced cell viability compared to controls: Day 1 (0.541±0.020 <i>vs.</i> 0.552±0.015, <i>F</i>=0.098, <i>P</i>=0.423), Day 2 (1.154±0.009 <i>vs.</i> 1.326±0.029, <i>F</i>=2.485, <i>P</i><0.001), Day 3 (2.453±0.041 <i>vs.</i> 2.653±0.031, <i>F</i>=0.479, <i>P</i><0.001), and Day 4 (3.685±0.038 <i>vs.</i> 3.836±0.021, <i>F</i>=6.804, <i>P</i><0.001). In colony formation assays, the overexpression group displayed a significant increase in colony numbers (254.667±23.861 <i>vs.</i> 186.000±16.703, <i>F</i>=0.865, <i>P</i>=0.015), whereas the knockdown group exhibited decreased colony formation (229.000±24.637 <i>vs.</i> 306.667±36.501, <i>F</i>=0.988, <i>P</i>=0.038). In Transwell assays, the EFHD2 overexpression group revealed enhanced migratory capacity [ (605.000±72.670) cells <i>vs.</i> (472.667±28.095) cells, <i>F</i>=2.462, <i>P</i>=0.042] and invasive potential [(767.333±21.221) cells <i>vs.</i> (414.333±16.623) cells, <i>F</i>=0.331, <i>P</i><0.001]. The knockdown group showed attenuated migration [(311.000±71.084) cells <i>vs.</i> (479.667±50.846) cells, <i>F</i>=0.718, <i>P</i>=0.029] and invasion [(247.667±48.263) cells <i>vs.</i> (34","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1224-1231"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in multi-source surveillance data integration and application of early warning indicators for respiratory infectious diseases].","authors":"D Z Huo, T Zhang, J Z Cui, X C Zhang, Y T Chi, Y N Wang, Z Wang, X Zhao, Z L Fan, C C Ye, C S Fang, Y M Li, Z J Li, W Z Yang, C Wang","doi":"10.3760/cma.j.cn112150-20250117-00055","DOIUrl":"10.3760/cma.j.cn112150-20250117-00055","url":null,"abstract":"<p><p>The integration of multi-source data and the establishment of early warning indicator systems constitute pivotal elements for advancing surveillance and early warning capacities in respiratory infectious diseases. Given the multifaceted transmission mechanisms and complex contributing factors inherent in respiratory infectious diseases, surveillance datasets and associated early warning indicators demonstrate notable heterogeneity and sophisticated interrelationships. Furthermore, as surveillance and early warning requirements significantly vary across diverse epidemiological scenarios, accurate assessment of the value and applicability of distinct data types and indicators is imperative. This paper systematically reviews and synthesizes recent advancements in surveillance data and early warning indicators for respiratory infectious diseases, drawing on both domestic and international research. Particular attention is dedicated to analyzing the applicability and efficacy of various data types and indicators within multiple practical contexts, aiming to provide robust theoretical frameworks and methodological guidance to facilitate the development of resilient and efficient surveillance and early warning systems for respiratory infectious diseases.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1311-1319"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Incidence trend of herpes zoster and postherpetic neuralgia in Beijing City from 2015 to 2022].","authors":"X M Li, Z A Li, D Zhao, L D Suo, Q H Wang, H H Wang, X H Peng, J B Pan, T Zhou, X Wang, M Zhou, T Wang, Z L Zhu, H Y Wang, Y F Wang, Y Q Wang, Y Feng, L Lu","doi":"10.3760/cma.j.cn112150-20241028-00854","DOIUrl":"10.3760/cma.j.cn112150-20241028-00854","url":null,"abstract":"<p><p><b>Objective:</b> To understand the incidence rate of herpes zoster (HZ) and postherpetic neuralgia (PHN) in Beijing, and analyze the incidence trend of HZ and PHN from 2015 to 2022. <b>Methods:</b> Cases of HZ and PHN from 2015 to 2022 were retrieved from the Hospital Information Systems (HIS) of all primary and above hospitals/clinics in three districts representing the urban, inner suburban, and outer suburban areas of Beijing. After duplication screening, the first visit cases were screened, and the incidence characteristics were described. The incidence rate of HZ and PHN in each year by sex and age group and the age-standardized incidence rate were calculated. The annual percentage increase (APC) of incidence rate was calculated using the Joint regression model, and the change trend was analyzed. <b>Results:</b> The age-standardized incidence rate of HZ in Beijing from 2015 to 2022 ranged from 7.44‰ to 10.05‰, with an average annual incidence rate of 8.95 ‰, significantly increasing with age (<i>P</i><0.001). The Joinpoint regression model showed that the overall age-standardized incidence of HZ remained relatively stable, with no significant difference (APC=2.28%, <i>t</i>=1.56, <i>P</i>=0.170). However, the incidence rate among the 0-19-year-old group exhibited a trend of decrease (APC=-10.70%, <i>t</i>=-6.29, <i>P</i><0.001). For PHN, the age-standardized incidence in Beijing ranged from 0.77‰ to 2.67‰, with an average annual incidence rate of 1.59‰ and a proportion of 9.48% to 26.86% among HZ cases. Both the incidence of PHN and its proportion among HZ cases increased with age (<i>P</i><0.001). The age-standardized incidence of PHN increased annually (APC=18.56%, <i>t</i>=9.02, <i>P</i><0.001). <b>Conclusion:</b> The incidence rate of HZ and PHN in Beijing continues to be at a high level, and PHN shows an increasing trend over time.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"59 8","pages":"1264-1269"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}