中华预防医学杂志最新文献

{"title":"[Current status and challenges of standard formulation in the field of infectious disease prevention and control in China].","authors":"L Y Wang, M Z Jiang, Z Y Wang, M J Yao, Y Guo, J Yan","doi":"10.3760/cma.j.cn112150-20250902-00849","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250902-00849","url":null,"abstract":"<p><p>The study obtained 1 358 current standards through the National Public Service Platform for Standards Information and systematically reviewed and analyzed the current distribution and demand for standards related to infectious diseases in China. In terms of content coverage, disease-specific standards predominated, accounting for 841 items (61.93%), whereas 517 standards (38.07%) were general standards involving two or more infectious diseases or a specific field of infectious diseases. From the perspective of prevention and control, the current standards are mainly concentrated in areas such as \"pathogen detection\" and \"disease diagnosis, \" while standards in fields including \"laboratory data security\" and \"drug prophylaxis\" remain relatively insufficient. In addition, the current standard system still faces several challenges, including long development cycles, insufficient cross-departmental collaboration, and limited alignment with international standards. It is therefore recommended to optimize the existing standards by controlling excessive growth while improving quality and to establish cross-departmental and multidisciplinary collaborative mechanisms to enhance the scientific rigor and systematic nature of standard development. These efforts may better address the challenges of infectious disease prevention and control and provide a reference for improving the standard system for infectious disease prevention and control in China.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 ","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research and development progress of pneumococcal conjugate vaccines based on the serotype distribution characteristics of pneumococci in China].","authors":"C L Fan, H Zheng, M Zeng, H Q He, L Wang, Y Liu, C H Zhang, Q F Xu, Y Z Li, C X Fu","doi":"10.3760/cma.j.cn112150-20250805-00756","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250805-00756","url":null,"abstract":"<p><p>Streptococcus pneumoniae (Spn) is one of the major pathogens responsible for morbidity and mortality worldwide, and pneumococcal diseases constitute a significant global public health burden, with a particularly high burden among children under five years of age and older adults. Based on differences in the structure of capsular polysaccharides, more than 100 pneumococcal serotypes have been identified to date. The pathogenicity of Spn is, to some extent, associated with immune evasion mediated by serotype-specific capsular polysaccharides; therefore, pneumococcal vaccines covering multiple serotypes have significant public health importance for the prevention and control of related diseases. With the promotion and application of pneumococcal vaccines in China, the serotype distribution of Spn has undergone dynamic changes, and serotype-specific epidemiological evidence as well as real-world evidence on vaccine use has continued to accumulate. This study systematically reviews the distribution characteristics of Spn serotypes and related diseases in China, as well as the current status of antimicrobial resistance; describes the immune protective mechanisms of pneumococcal conjugate vaccines (PCVs) against different serotypes; compares the immunogenicity and protective effects of PCVs with different valences; and discusses the development directions and key scientific issues of higher-valent PCVs and universal pneumococcal vaccines, in order to provide evidence reference and scientific support for the design of PCV serotype coverage and the optimization of immunization strategies in China.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 ","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of the pathogenic spectrum and epidemiological characteristics of acute respiratory infection in Henan Province from 2024 to 2025].","authors":"X Y Wang, X X Zhang, K C Yang, M H Seng, S Zhao, B H Du, J Li, Y F Ji, L B Shi, Y Y Liu, Y Y Zhang","doi":"10.3760/cma.j.cn112150-20250430-00376","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250430-00376","url":null,"abstract":"<p><p>This study aimed to analyze the pathogen spectrum and epidemiological characteristics of acute respiratory infection (ARI) in Henan Province and provide evidence for targeted regional prevention and control strategies. Using the provincial multi-pathogen surveillance system for ARI, respiratory samples were collected from influenza-like illness cases at 18 sentinel hospitals between April 2024 and March 2025. Eleven respiratory pathogens were detected using multiplex PCR, including influenza virus, SARS-CoV-2, respiratory syncytial virus, adenovirus, human metapneumovirus, parainfluenza virus, human coronavirus, human bocavirus, rhinovirus, enterovirus, and Mycoplasma pneumoniae. Descriptive analysis was conducted to examine demographic, seasonal, and regional distribution patterns. Among 11 794 samples tested, the overall positivity rate was 55.05% (6 493/11 794), with 12.77% (829/6 493) showing co-infections. Influenza virus (19.83%), HRV (9.08%), and hMPV (7.07%) were predominant. Age-specific patterns emerged: RSV, PIV, HCoV, hMPV, HBoV, HRV, and EV were more prevalent in children under five years. M. pneumoniae was most common in 5-14 years old. Seasonal trends showed that influenza virus and hMPV peaked in winter, SARS-CoV-2 and EV in summer, RSV in spring, PIV in spring/summer, HRV in spring/autumn, and M. pneumoniae in summer/autumn. Regional variations revealed higher detection rates for influenza virus in southern Henan, HRV in western Henan. Co-infection patterns differed significantly: SARS-CoV-2 and influenza virus mainly occurred as single infections, while HBoV and EV showed notable co-infection trends. In conclusion, ARI in Henan demonstrate multi-pathogen co-circulation, with influenza virus, HRV, and hMPV being predominant. Children under five years require prioritized intervention. Sustained multi-pathogen surveillance is essential for effective control.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"566-572"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of the spatial distribution characteristics of rifampicin-resistant tuberculosis patients in Shaanxi Province from 2018 to 2024].","authors":"K K Li, H W Zhang, Y L Deng, X B Liu, Z Q He","doi":"10.3760/cma.j.cn112150-20250513-00422","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250513-00422","url":null,"abstract":"<p><p>This study aimed to analyze the spatial distribution characteristics of rifampicin-resistant tuberculosis (RR-TB) patients in Shaanxi Province from 2018 to 2024. A cross-sectional study was conducted to collect data on 3 335 cases of RR-TB patients registered from 2018 to 2024 in Shaanxi Province, China, from the tuberculosis sub-system of the China Disease Control and Prevention Information System. Statistical analysis was performed using SPSS 25.0 software. ArcGIS 10.8 software was used to build the spatial distribution map of the annual reported incidence rate of RR-TB at the county (district, city) level, and construct the global spatial self-correlation and hotspot analysis on the data of RR-TB patients in Shaanxi Province, so as to explore the spatial aggregation of the disease. The results showed that there were significant differences in the reported incidence of RR-TB patients in Shaanxi Province among the years (<i>χ</i>²=177.04, <i>P</i><0.001). The proportion of treatment-naive patients (71.33%) was higher than that of retreatment patients (28.67%, <i>χ</i>²=607.18, <i>P</i><0.001). The spatial distribution showed that there were high incidence areas and spatial aggregation characteristics of RR-PTB patients in Shaanxi Province from 2018 to 2024. Spatial self-correlation analysis showed that the spatial clustering of RR-TB reported incidence in 2018, 2022, and 2024 was significant (<i>P</i><0.05). The average annual reported incidence local hotspot analysis showed that there were 9 hotspot areas, including 7 positive hotspot areas of Hanbin County, Pingli County, Ziyang County, Langao County, Xunyang City, Zhenping County District of Ankang City, and Zhenba County of Hanzhong City, and 2 negative hotspot areas of Zhouzhi County and Yangling District of Xi'an City. The analysis of the local hotspot year by year showed that the positive hotspot area increased from 7 in 2018 to 11 in 2022, and the agglomeration range showed an expanding trend year by year, mainly concentrated in some counties of Hanzhong City and Ankang City, while the negative hotspot area had no obvious concentration trend. In summary, the incidence of RR-TB in Shaanxi Province shows obvious spatial aggregation and regional distribution differences. The areas with higher incidence are mainly concentrated in southern Shaanxi, and the range of the positive hotspot area shows an expanding trend year by year.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"560-565"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of trends in the disease burden of hepatitis A and hepatitis E in China from 1990 to 2021].","authors":"X T Zhu, J J Lyu, Y Feng, X Meng, L Zhang, B Y Yan","doi":"10.3760/cma.j.cn112150-20250418-00330","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250418-00330","url":null,"abstract":"<p><p>Based on data from the Global Burden of Disease 2021 (GBD 2021) database, we analyzed the trends in incidence, mortality, and disability-adjusted life years (DALYs) for hepatitis A (HA) and hepatitis E (HE) in China from 1990 to 2021. The average annual percentage change in disease burden indicators was calculated using the Joinpoint regression model. Compared with 1990, the numbers of incident cases, deaths, and DALYs, as well as the age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR) for both HA and HE in China in 2021 decreased substantially. However, the decline in each indicator was slower for HE than for HA. Throughout the study period, the average annual standardized rates for all indicators were higher in males than in females. Although the ASMR and ASDR for HA and HE showed a decreasing trend across all age groups, the ASIR exhibited an upward trend in specific age brackets: for HA, increases were observed among individuals aged 20-34 years and those aged ≥60 years; for HE, increases were noted among children aged 0-4 years and adults aged ≥55 years. In conclusion, the disease burden of both HA and HE in China declined between 1990 and 2021, though the reduction was comparatively slower for hepatitis E.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"555-559"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Investigation on the incidence of pertussis and the carriage and distribution characteristics of Bordetella pertussis among healthy individuals in certain regions of Xinjiang Uygur Autonomous Region from 2023 to 2024].","authors":"T Tian, W H Fu, J Li, Wuqierjiafu Caipilima, Yesty Muheiyat, Halimubiek Nazhaerbiek, Z G Lan, N Xie","doi":"10.3760/cma.j.cn112150-20250508-00405","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250508-00405","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the incidence of pertussis and the carriage and distribution characteristics of Bordetella pertussis (BP) among healthy individuals in certain regions of Xinjiang during 2023-2024, providing scientific evidence for the prevention and control of pertussis. <b>Methods:</b> Patients' information in Urumqi, Karamay and Ili governorates from 2023 to 2024 was collected in the Chinese Disease Control and Prevention Information System, and the incidence of pertussis was analyzed. A multi-stage sampling method was used to select 1-2 districts (counties) as survey points in each of the above regions from June to July 2023 and October to November 2024. Nasopharyngeal swabs from healthy individuals were collected, and their BP-carrying status was analyzed through on-site vaccination, bacterial culture, and polymerase chain reaction experiments. <b>Results:</b> From 2023 to 2024, Karamay had a high incidence of pertussis, with a rate of 140.53/100 000. The incidence rate of pertussis declined with age (<i>χ</i>²=4 327.14, <i>P</i><0.001), with the highest incidence rate in the 0-4 year age group (269.02/100 000) and the lowest in the ≥20-year age group (3.37/100 000). A total of 971 nasopharyngeal swab samples were collected from healthy individuals, with a BP carrier positivity rate of 1.54% (15/971). The BP carrier positivity rate was higher in the ≥20-year age group, at 2.42% (4/165). <b>Conclusion:</b> Confirmed cases of pertussis in some areas of Xinjiang in 2023-2024 are highly prevalent in the 0-4 year age group, with a higher positive rate of BP carriers among healthy individuals aged ≥20, suggesting that adults may be a hidden source of pertussis transmission. Attention should be paid to the management of pertussis in children, while strengthening monitoring of adults.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"519-524"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress in the application of RPA-CRISPR/Cas13a technology in the detection of pathogenic microorganisms].","authors":"T Ji, T Wang, K Yu, Y Z Gao, X Z Gao","doi":"10.3760/cma.j.cn112150-20250430-00378","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250430-00378","url":null,"abstract":"<p><p>Recombinase polymerase amplification (RPA) is an emerging method for nucleic acid amplification. It can be performed under low-temperature conditions, making it suitable for point-of-care testing. Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 13 (CRISPR/Cas13a), a type Ⅵ CRISPR-Cas system, employs a single-subunit RNA-guided Cas endonuclease to target exogenous RNA and exhibits distinct trans-cleavage activity. The integration of CRISPR/Cas13a with RPA technology significantly enhances detection sensitivity and accuracy, demonstrating considerable potential for molecular diagnostics. The RPA-CRISPR/Cas13a platform has achieved notable success in areas such as food safety, environmental monitoring, and clinical diagnosis, and has become an important tool in modern biomedical research. This article provides an in-depth analysis of the fundamental principles of RPA-CRISPR/Cas13a technology and comprehensively reviews its applications in pathogenic microorganism detection, aiming to offer new insights for accurate pathogen diagnosis.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"622-630"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Distribution characteristics of gut microbiota among residents in 16 provinces of China in 2018].","authors":"X F Zhang, F X Guan, Y F Ouyang, Y L Wei, F F Huang, J G Zhang, W W Du, X F Jia, L Li, J Bai, H J Wang, C Su","doi":"10.3760/cma.j.cn112150-20250407-00283","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250407-00283","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the distribution characteristics of gut microbiota among residents across 16 provinces of China in 2018, and explore the diversity and compositional differences of gut microbiota. <b>Methods:</b> A total of 10 150 residents who participated in the 2018 China Health and Nutrition Survey (CHNS) and had complete basic information and fecal sample collection data were enrolled as the research subjects. A unified structured questionnaire was used to collect their basic information, and fecal samples were collected from the research subjects. The Illumina HiSeq PE-250 platform was adopted for 16S rRNA gene sequencing on the DNA of the fecal samples. The Wilcoxon rank sum test was used to compare the intergroup differences in α-diversity. Permutational multivariate analysis of variance (PERMANOVA) was performed for β-diversity analysis, and linear discriminant analysis effect size (LEfSe) analysis was applied to compare the differences in gut microbial genera between groups. <b>Results:</b> The core gut microbial genera of Chinese residents included <i>Blautia</i>, <i>Bifidobacterium</i>, <i>Romboutsia</i>, and <i>Eubacterium hallii group</i>. Alpha diversity was significantly higher in females, rural residents, and southern provinces, with age-associated increases (all <i>P</i><0.050). Beta diversity analysis revealed the largest compositional differences by province (<i>R</i>²=0.025, <i>P</i>=0.010), followed by age (<i>R</i>²=0.016, <i>P</i>=0.010). The LEfSe differential analysis of gut microbiota composition among residents with different characteristics showed that <i>Bifidobacterium</i>(LDA=4.88) and <i>Faecalibacterium</i>(LDA=3.92) were the dominant genera in residents less than 18 years old, and <i>Escherichia-Shigella</i>(LDA=4.33) and <i>Lactobacillus</i>(LDA=3.98) predominated in those≥75. Females exhibited higher abundances of beneficial taxa [e. g. <i>Bifidobacterium</i>(LDA=3.99), <i>Akkermansia</i>(LDA=3.14)], while rural residents had elevated <i>Romboutsia</i>(LDA=4.08), <i>Clostridium_sensu_stricto_1</i>(LDA=4.07), and <i>Escherichia-Shigella</i>(LDA=3.52). Inter-province comparisons highlighted Beijing as having the most distinct microbiota. <b>Conclusion:</b> In the gut microbiota of residents in 16 provinces of China, the <i>Blautia</i>, <i>Bifidobacterium</i>, <i>Romboutsia</i>, and <i>Eubacterium hallii</i> are the main genera<i>.</i> The diversity and composition of the gut microbiota are significantly influenced by geographical location and age.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"482-488"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in personalized dosing strategies for antipsychotic drugs].","authors":"X Y Wang, C Y Li, L Zhang, S J Yin, W Li, Y L Tan, S J Pan","doi":"10.3760/cma.j.cn112150-20250514-00427","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250514-00427","url":null,"abstract":"<p><p>Mental disorders have emerged as a significant global challenge in the field of public health, with antipsychotic pharmacotherapy serving as the primary intervention. Traditional treatment paradigms typically employ population-based pharmacotherapy guided by psychiatrists' clinical experience, which often fail to account for interindividual heterogeneity in pharmacokinetic and pharmacodynamic profiles. With the advancement of precision medicine concepts, comprehensive assessment of patients genetic and metabolic parameters has now evolved into a crucial approach for guiding personalized antipsychotic dosing strategies. This article systematically summarizes therapeutic drug monitoring, pharmacogenomics, pharmacometabonomics, and quantitative pharmacology techniques, aiming to provide a reference for optimizing individualized antipsychotic treatment regimens.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"640-647"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study on the status of media exposure to tuberculosis prevention information and its impact on health beliefs and preventive behaviors among lower-grade university students in Guangzhou City].","authors":"Y T Xu, J Y Yang, Y J Hu, X S Lin, L Q He, J W Wang, R X Zhong, H L Peng, L Chen","doi":"10.3760/cma.j.cn112150-20250711-00659","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20250711-00659","url":null,"abstract":"<p><p>Based on the Health Belief Model (HBM), this study explored the level of media exposure to tuberculosis (TB) prevention information and its impact on health beliefs and prevention behaviors among lower-grade university students in selected universities in Guangzhou City.A stratified cluster random sampling method was employed, and from May to June 2025, the Department of Tuberculosis Prevention and Control of Guangzhou Chest Hospital conducted a questionnaire survey among first-year and second-year students from 18 universities in Guangzhou City, yielding 1 909 valid responses. Multiple linear regression was employed to analyze the impact of media exposure to tuberculosis prevention information on health beliefs and preventive behaviors. The results showed that students scored higher on acquiring TB prevention information via new media (3.6±0.9) than via traditional media (3.3±0.9), yet exposure frequency to both was low (new media: 2.6±0.9; traditional media: 2.3±1.0). Content related to TB prevention methods received the highest attention score (3.6±0.8). Regression analysis indicated that media type and content focus significantly influenced all HBM dimensions (<i>P</i><0.01), while exposure frequency only affected perceived susceptibility, barriers, and self-efficacy (<i>P</i><0.01). Media exposure, education level, and gender collectively impacted TB prevention behaviors (<i>P</i><0.01). In conclusion, lower-grade university students in Guangzhou City primarily rely on new media for TB information, but exposure frequency and engagement remain insufficient. Media type and content focus differentially shape health beliefs and preventive behaviors.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"60 4","pages":"577-583"},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}