中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240817-00664
X Q Bai, C Y Zhang, R Du, Y Y Ren, Z S Li, H G Yan, Z Wang, X H Zhang, X J Quan, J Li, L L Han, X Xu, Y Zhou, M B Liu, H Y Zhang, L Li
{"title":"[Correlation analysis between myopia growth and physical development parameters of school-age children in Shihezi area, Xinjiang Uyghur Autonomous Region].","authors":"X Q Bai, C Y Zhang, R Du, Y Y Ren, Z S Li, H G Yan, Z Wang, X H Zhang, X J Quan, J Li, L L Han, X Xu, Y Zhou, M B Liu, H Y Zhang, L Li","doi":"10.3760/cma.j.cn112150-20240817-00664","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240817-00664","url":null,"abstract":"<p><p><b>Objective:</b> To study the correlation between myopia growth and physical development of primary school student in Shihezi area of Xinjiang Uyghur Autonomous Region by measuring the ocular biometry and physical parameters of the eye, and to provide an objective basis for the development of myopia prevention and control. <b>Methods:</b> A cross-sectional study design was used. The Grade 1-6 students from 33 schools in Shihezi area were randomly selected in October 2023. The children were classified according to age into the low age group (6-9 years) and the high age group (10-13 years).The children's height, weight, axial length (AL), maximum keratometry (steepest keratometry, K1), and minimum keratometry (flattest keratometry, K1) were measured. The body mass index (BMI), keratometric astigmatism (ΔK), mean keratometry (K), corneal radius (CR) and AL/CR were calculated. Correlation analyses were performed between ocular biometry and physical parameters. LASSO regression analysis was used to screen the best variables, and linear regression models were constructed after adjusting for confounding factors of age and sex. <b>Results:</b> A total of 3 986 children aged 6-13 years were included in this study, including 2 094 boys (52.53%) and 1 892 girls (47.47%); 2 162 in the lower age group and 1 824 in the upper age group. Girls had higher K, ΔK and AL/CR values than boys (43.38 D <i>vs</i> 42.7 D, <i>t</i>=-7.84,<i>P</i><0.01; 1.1 D <i>vs</i> 1.01 D, <i>t</i>=-2.14,<i>P</i>=0.03; 2.97 <i>vs</i> 2.96, <i>t</i>=3.32,<i>P</i>=0.02). Boys had higher AL, height, weight and BMI than girls (23.47 mm <i>vs</i> 23.02 mm, <i>t</i>=13.77,<i>P</i><0.01; 1.34 m <i>vs</i> 1.33 m, <i>t</i>=3.02,<i>P</i>=0.03; 32 kg <i>vs</i> 29.5 kg, <i>t</i>=7.82,<i>P</i><0.01; 17.4 <i>vs</i> 16.52, <i>t</i>=10.36, <i>P</i><0.01). LASSO regression was used to screen the 3 physical parameter variables (height, weight, and BMI) to determine that height was the best physical parameter variable for AL/CR. After adjusting for confounders, it was shown that in the low age group (6-9 years), there was a significant positive correlation between children's height and AL/CR (<i>b</i>=0.174, 95%<i>CI</i>: 0.106 to 0.241, <i>P</i><0.001), whereas in the high age group (10-13 years), there was no correlation between children's height and AL/CR (<i>b</i>=0.086, 95%<i>CI</i>:-0.038 to 0.21, <i>P</i>=0.174). <b>Conclusion:</b> There was a positive correlation between height and myopia growth in the lower age group of children in Shihezi area, Xinjiang Uyghur Autonomous Region; there was no correlation between height and myopia growth in the higher age group.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1961-1966"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240625-00501
J C Wu, Q Wei
{"title":"[A comprehensive review and future prospects of biobanking pathogenic microorganisms causing human infections in China].","authors":"J C Wu, Q Wei","doi":"10.3760/cma.j.cn112150-20240625-00501","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240625-00501","url":null,"abstract":"<p><p>Pathogenic microorganisms serve as a crucial material foundation for life sciences and the progression of the biotechnology industry, and they also constitute an essential prerequisite for scientific innovation. Over the past century, global initiatives aimed at the collection and utilization of microorganisms have been instrumental in facilitating fundamental scientific research and fostering advancements in biotechnology. This article provides a comprehensive review of the history of culture collections of human-infecting pathogenic microorganisms in China, with a specific emphasis on developments over the past two decades. It delineates and consolidates four distinct stages of development along with their notable achievements. Additionally, the paper examines the positioning, responsibilities, development strategies, and measures associated with culture collections in this new historical context, with the objective of offering significant technical support for the monitoring and early warning of potential global pandemics in the future, thereby ensuring national biosecurity.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1949-1954"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240612-00461
J M Li, L K Lyu, Z L Tan, Y Zhang
{"title":"[Analysis of the level of serum-neutralizing antibodies against Coxsackievirus A6 in a healthy population in Tianjin City from 2014 to 2020].","authors":"J M Li, L K Lyu, Z L Tan, Y Zhang","doi":"10.3760/cma.j.cn112150-20240612-00461","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240612-00461","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the level of serum-neutralizing antibodies against Coxsackievirus A6 (CVA6) in a healthy population in Tianjin City from 2014 to 2020. <b>Methods:</b> From March 2014 to March 2020, 5 492 healthy volunteers were recruited in Tianjin City. The demographic information, personal hygiene habits, living environment hygiene, contact history with hand, foot and mouth disease cases within 6 months before the survey, history of upper respiratory tract infection, and medical history of the subjects were investigated using a self-designed questionnaire. Venous blood was collected from the volunteers, and the level of serum anti-CVA6 IgG neutralizing antibodies was determined by the micro-neutralization assay. The level of CVA6-neutralizing antibodies was compared in different years, regions, and age groups, and the influencing factors in healthy individuals were analyzed by an ordered logistic regression model. <b>Results:</b> The age of 5 492 healthy volunteers ranged from 0 to 77, with <i>M</i> (<i>Q</i><sub>1</sub>, <i>Q</i><sub>3</sub>) of age being 21 (7, 32) years old, and a male-to-female ratio of 1∶1.09. The high, medium and low levels of CVA6-neutralizing antibodies among the volunteers were 5.39% (296), 30.35% (1 667) and 64.26% (3 529). The proportion of volunteers with high levels of CVA6-neutralizing antibodies decreased from 54.63% (437/800) in 2014 to 30.01% (229/763) in 2020, and it also decreased with age (all <i>P</i> values <0.001). The results of the ordered logistic regression model analysis showed that compared with those aged >35 years, volunteers aged 0-5 years had higher levels of CVA6-neutralizing antibodies [<i>OR</i> (95%<i>CI</i>): 1.39 (1.16-1.67)]. Compared with those who did not wash their hands after going out and had poor living environments, volunteers who washed their hands after going out, had good and general living environments and had lower levels of CVA6-neutralizing antibodies [<i>OR</i> (95%<i>CI</i>): 0.80 (0.70-0.91), 0.52 (028-0.88) and 0.54 (0.31-0.96), respectively]. <b>Conclusion:</b> The level of CVA6-neutralizing antibodies in Tianjin City remains at a relatively high level from 2014 to 2020 and shows a decreasing trend over the years.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1994-1998"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240928-00781
{"title":"[Expert consensus on subcutaneous cluster immunotherapy of inhaled allergens].","authors":"","doi":"10.3760/cma.j.cn112150-20240928-00781","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240928-00781","url":null,"abstract":"<p><p>Allergen-specific immunotherapy is the only etiological treatment that can prevent the progression of allergic diseases at present. Cluster immunotherapy is an improved immunotherapy regimen, which shortens the dose escalation period from 4-6 months in conventional regimen to 1-8 weeks. In the past, there was no consensus or guideline to guide the standardized application of subcutaneous cluster immunotherapy of inhaled allergens in China. Based on relevant research evidence at home and abroad and the opinions of industry experts, this consensus systematically expounded the indications and contraindications of cluster immunotherapy, and proposed that the cluster scheme took effect earlier than the conventional scheme, with similar incidence of systemic allergic reaction with the conventional scheme. At the same time, the risk factors and preventive measures of systemic allergic reaction caused by cluster immunotherapy were emphasized. This consensus aims to improve the understanding of cluster immunotherapy among medical staff in China and guide the standardized application and management of cluster immunotherapy.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1825-1834"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240402-00269
S X Jiang, X Z Li, X M Zhu, Q S Li, Q Y Wei
{"title":"[Research progress on pollen monitoring and pollen allergenicity of ragweed].","authors":"S X Jiang, X Z Li, X M Zhu, Q S Li, Q Y Wei","doi":"10.3760/cma.j.cn112150-20240402-00269","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240402-00269","url":null,"abstract":"<p><p>Ragweed, as an exotic invasive species, which is one of the most important allergens for hay fever, has been invading China for more than 80 years. The increasing number of people with hay fever makes effective treatment, as well as the prevention and control of pollen transmission critical. This article delves into a comprehensive research summary focusing on the allergenic properties of ragweed pollen, its pathogenic characteristics, epidemiological patterns, monitoring and control measures, as well as concentrated management approaches. By exploring these aspects, it provides a reference framework for scientifically sound integrated control methods that encompass biological management, pharmacological treatments, and specific immunotherapy, ultimately aiming to prevent and mitigate the effects of ragweed pollen exposure.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1866-1872"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240521-00414
Y Wang, Y F Ren, J Qi, X Liang, R F Zhang
{"title":"[The advances of component resolved diagnosis in IgE-mediated cow's milk protein allergy].","authors":"Y Wang, Y F Ren, J Qi, X Liang, R F Zhang","doi":"10.3760/cma.j.cn112150-20240521-00414","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240521-00414","url":null,"abstract":"<p><p>Cow's milk protein allergy is the most common food allergy in infants and young children, and its prevalence has been increasing in recent years. The use of appropriate diagnostic methods is essential for the management of patients. Oral food challenges are not yet widely used in clinical practice, and new and more effective methods are still being sought, including component resolved diagnosis. Component resolved diagnosis has been introduced into the field of clinical allergy, which provides a new understanding for the diagnosis and treatment of allergic diseases. This article reviews the clinical application of component resolved diagnosis in IgE-mediated cow's milk protein allergy, especially the components of cow's milk protein allergy and the identification of co-sensitization, the research progress of diagnosis, the prediction of the development of tolerance and the risk of allergic reactions, the guidance of allergen immunotherapy and the development of personalized diet for patients, in order to provide a basis for the diagnosis, treatment and prevention of IgE-mediated cow's milk protein allergy.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1873-1878"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240625-00504
F F Li, X Lyu, J L Zhang, X Liu, B H Li, B C Li, P T Liu, C Y Quan, Z Y Li, M Hu
{"title":"[Analysis of drug-resistance mutations and treatment of mycoplasma pneumonia in children in Hunan Province in 2023].","authors":"F F Li, X Lyu, J L Zhang, X Liu, B H Li, B C Li, P T Liu, C Y Quan, Z Y Li, M Hu","doi":"10.3760/cma.j.cn112150-20240625-00504","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20240625-00504","url":null,"abstract":"<p><p>To investigate the drug-resistance mutations and treatment of hospitalized children with Mycoplasma pneumoniae pneumonia (MPP) in Hunan Province. Children with pneumonia, who were hospitalized in the pediatric ward of the Second Xiangya Hospital of Central South University from January 1, 2023, to December 31, 2023, were enrolled in this study, and their clinical data was also collected. The targeted next-generation sequencing (tNGS) was used to detect Mycoplasma pneumoniae (MP) infection and drug-resistance mutations, and the drug-resistance and treatment in children with MPP were also analyzed. A total of 125 children with pneumonia were involved in this study, including 70 children in the MPP group and 55 children in the bacterial pneumonia group. The results showed that there were 41 boys and 29 girls with an average age of (6.50±3.45) years, with the most common group being the school-age group (age≥6 years). The clinical symptoms were characterized by fever and cough. Laboratory examination showed that the white blood cell and neutrophil counts in the MPP group were lower than those in the bacterial pneumonia group, while the lymphocyte ratio and hemoglobin levels in the MPP group were higher than those in the bacterial pneumonia group, with statistically significant differences (all <i>P</i><0.05). Twelve children (17.14%) in the MPP group had severe pneumonia, and all children with severe pneumonia had 23Sr RNA A2063G and/or A2064G mutations. The tNGS detected 60 cases of MPP resistance gene mutations, including 59 cases (98.33%) of A2063G mutation in 23Sr RNA and one case (1.67%) of A2064G mutation in 23Sr RNA. There was a significant difference in the positive rate of drug-resistance mutations among patients of different age groups (χ<sup>2</sup>=7.991, <i>P</i>=0.021). A total of 63 children (90.00%) with MPP were treated according to the results of drug-resistance mutations, and seven children (70.00%) with MPP without drug-resistance mutations were treated according to the tNGS results. In children with the drug resistance of MPP, 46 cases (95.83%) of non-severe pneumonia and 10 cases (83.33%) of severe pneumonia were treated according to the tNGS results. All patients had a good prognosis, with no deaths reported and a median hospital stay <i>M</i> (<i>Q</i><sub>1</sub>, <i>Q</i><sub>3</sub>) of 9 (7, 11) days. In conclusion, MPP is more common in children aged≥6 years old in Hunan Province, and the detection of drug-resistant mutations includes A2063G and A2064G, with A2063G being the main one. The positive rate of drug-resistant mutations is related to age.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"2038-2044"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20231212-00436
T Chen, A L Li, Z Y Yin, H Gan, X H Zheng, Z F Huang, B Q Sun
{"title":"[Analysis of risk factors for allergic rhinitis in preschool children with multiple allergic diseases in Guangzhou City].","authors":"T Chen, A L Li, Z Y Yin, H Gan, X H Zheng, Z F Huang, B Q Sun","doi":"10.3760/cma.j.cn112150-20231212-00436","DOIUrl":"https://doi.org/10.3760/cma.j.cn112150-20231212-00436","url":null,"abstract":"<p><p>This study aims to analyze the differentiating factors between only allergic rhinitis and allergic rhinitis combined with other allergic diseases in pre-school children and to explore the impact of relevant family and maternal factors during pregnancy on pediatric allergic diseases.The study employed an epidemiological cross-sectional survey design, conducted from January to June 2022 at the Helong Street Health Service Center in Baiyun District, Guangzhou City, China. This cross-sectional investigation focused on 15 preschool education centers within the jurisdiction. It encompassed a total of 4 661 pre-school children aged 3-6 years within the district, resulting in the collection of 3 437 valid questionnaires. The study utilized an online survey, covering aspects such as children's birth conditions, early living environment, maternal lifestyle and emotional state during pregnancy, and paternal information. The questionnaire was designed by an expert team and incorporated advanced logic functions to ensure data accuracy. Diagnosis of allergic diseases included evaluation of symptoms such as rhinitis, asthma, eczema and along with collecting family member's allergy information. Factors like maternal emotional stress during pregnancy, premature birth, and breastfeeding were also considered. The analysis of frequency differences between groups was conducted using the Chi-square test. The distribution differences between two groups were examined using the <i>t</i>-test or Mann-Whitney <i>U</i> test. Additionally, binary logistic regression analysis was employed to identify risk factors for the occurrence of allergic diseases. To illustrate the distribution and co-occurrence of different allergic diseases in children, upset plots were created. Furthermore, forest plots were utilized to analyze the risk factors. The study included 455 children with only allergic rhinitis and 759 children with rhinitis combined with other allergic diseases. The results showed no significant demographic differences between the two groups. Logistic model results indicated that children with allergic rhinitis who had suffered from severe eczema within the first 12 months had a <i>OR</i>(95%<i>CI</i>):19.818 times (2.670-147.095) higher probability of developing combined allergic diseases than those without eczema, while the probability increased 2.345 times (1.825-3.013) for those with mild to moderate eczema. A higher level of maternal education was also identified as a risk factor, increasing the risk by about 1.5 times. Additionally, the risk of developing combined allergic diseases in children with one allergic parent was <i>OR</i>(95%<i>CI</i>):1.662 times (1.273-2.170) higher than in those with non-allergic parents, and 2.181 times (1.504-3.163) higher if both parents had allergies. Moreover, negative maternal emotional stress during pregnancy was more significant in children with combined allergic diseases. In conclusion, severe eczema in the first 12 months","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 12","pages":"1912-1920"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240910-00723
E M Ding, W Z Yang
{"title":"[Focus on and response to climate-sensitive diseases].","authors":"E M Ding, W Z Yang","doi":"10.3760/cma.j.cn112150-20240910-00723","DOIUrl":"10.3760/cma.j.cn112150-20240910-00723","url":null,"abstract":"<p><p>With the current climate change characterized by global warming becoming more severe, the increasing frequency of extreme weather events such as heatwaves, cold waves, sandstorms, floods, and droughts caused by climate change has posed serious threats to human health. Climate change is not only a major public health challenge in China, but also a focus problem in global. This article focuses on climate-sensitive diseases and summarizes and reviews the latest scientific facts and progress on how climate change impacts infectious diseases and chronic non-communicable diseases. It further proposes measures and strategies for addressing climate-sensitive diseases with public health in center, providing ideas and suggestions for scientifically addressing climate-sensitive diseases in the future.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 ","pages":"1940-1948"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华预防医学杂志Pub Date : 2024-12-06DOI: 10.3760/cma.j.cn112150-20240802-00622
{"title":"[Expert consensus on the diagnosis and management of IgE mediated food allergy in children].","authors":"","doi":"10.3760/cma.j.cn112150-20240802-00622","DOIUrl":"10.3760/cma.j.cn112150-20240802-00622","url":null,"abstract":"<p><p>The prevalence of food allergy in children is increasing, which seriously affects the quality of life of children and their families. Among children and adolescents, IgE-mediated food allergy is the most common type. In recent years, allergen specific IgE (sIgE) and skin prick testing (SPT) have been widely used in clinical practice, with component resolved diagnosis (CRD) also gaining traction for precise diagnosis of IgE-mediated food allergy. However, a challenge persists in clinical practice due to the tendency to over-interpret food allergen test results without considering the patient's clinical history. While food avoidance remains the most effective treatment for IgE-mediated food allergy, there are varying approaches to clinical management. Strict food avoidance for non-severe food allergies may increase the patient's burden and impact their quality of life. To address these challenges, a consensus on the diagnosis and management of IgE-mediated food allergy in children has been developed based on the latest guidelines and research evidence. This consensus aims to guide physicians in standardizing the management of IgE-mediated food allergy in children.</p>","PeriodicalId":24033,"journal":{"name":"中华预防医学杂志","volume":"58 ","pages":"1807-1824"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}