World Journal of Clinical Cases最新文献

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Prognostic factors of early recurrence after complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. 完全细胞清除手术和腹腔内热化疗后早期复发的预后因素。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6057
Chao-Yu Chen, Tzu-Hao Huang, Li-Wen Lee, Jrhau Lung, Yu-Che Ou, Chien-Hui Hung, Huei-Chieh Chuang, Min-Chi Chen, Ting-Yao Wang
{"title":"Prognostic factors of early recurrence after complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.","authors":"Chao-Yu Chen, Tzu-Hao Huang, Li-Wen Lee, Jrhau Lung, Yu-Che Ou, Chien-Hui Hung, Huei-Chieh Chuang, Min-Chi Chen, Ting-Yao Wang","doi":"10.12998/wjcc.v12.i27.6057","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6057","url":null,"abstract":"<p><strong>Background: </strong>Although cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) offer the potential for long-term survival in peritoneal carcinomatosis, outcomes following CRS/HIPEC vary significantly.</p><p><strong>Aim: </strong>To identify the clinical factors associated with progression-free survival (PFS) after complete CRS/HIPEC in patients with colorectal/high-grade appendiceal, ovarian, and gastric cancers.</p><p><strong>Methods: </strong>We retrospectively evaluated the risk of recurrence within 1 year after CRS/HIPEC and its impact on overall survival (OS) in patients recruited between 2015 and 2020. Logistic regression models were used to assess the prognostic factors for the risk of recurrence within 1 year. Kaplan-Meier survival curves and Cox proportional hazards models were used to evaluate the association between recurrence and OS.</p><p><strong>Results: </strong>Of the 80 enrolled patients, 39 had an unfavorable PFS (< 1 year) and 41 had a favorable PFS (≥ 1 year). Simple logistic models revealed that the patients with a completeness of cytoreduction score of 0 (CC-0) or length of CRS ≤ 6 h had a favorable PFS [odds ratio (OR) = 0.141, <i>P</i> = 0.004; and OR = 0.361, <i>P</i> = 0.027, respectively]. In multiple logistic regression, achieving CC-0 was the strongest prognostic factor for a favorable PFS (OR = 0.131, <i>P</i> = 0.005). A peritoneal cancer index score > 12 was associated with a lower rate of achieving CC-0 (<i>P</i> = 0.027). The favorable PFS group had a significantly longer OS (median 81.7 mo <i>vs</i> 17.0 mo, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Achieving CC-0 was associated with a lower early recurrence rate and improved long-term survival. This study underscores the importance of selecting appropriate candidates for CRS/HIPEC to manage peritoneal carcinomatosis.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral candidiasis and potential risk factors among disabled and non-disabled in Al-Baha region, Saudi Arabia. 沙特阿拉伯巴哈地区残疾人和非残疾人的口腔念珠菌病和潜在风险因素。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6077
Abdullah Ali H Alzahrani, Nagesh Bhat, Pankaj Kukreja, Eltayeb Mohammed Alhassan, Abdallah Ibrahim A Mudawi, Faisal A Alzahrani, Mohammad A Albanghali
{"title":"Oral <i>candidiasis</i> and potential risk factors among disabled and non-disabled in Al-Baha region, Saudi Arabia.","authors":"Abdullah Ali H Alzahrani, Nagesh Bhat, Pankaj Kukreja, Eltayeb Mohammed Alhassan, Abdallah Ibrahim A Mudawi, Faisal A Alzahrani, Mohammad A Albanghali","doi":"10.12998/wjcc.v12.i27.6077","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6077","url":null,"abstract":"<p><strong>Background: </strong>Oral <i>candidiasis</i> (OC) is an oral health disease that could influence patients' oral health quality of life.</p><p><strong>Aim: </strong>To estimate prevalence of OC among disabled and non-disabled individuals and its potential risk factors in the Al-Baha region, Saudi Arabia.</p><p><strong>Methods: </strong>An observational cross-sectional study was carried out among 148 disabled and non-disabled participants. The technique of concentrated oral rinse employing the Sabouraud Dextrose Agar medium accompanied with 0.05% chloramphenicol was conducted to assess and isolate <i>candida</i>. Oral examination using the World Health Organization guidelines was conducted to examine participants' oral health status. A pre-designed questionnaire was also used to evaluate sociodemographic, medical history, and oral hygiene habits of the studied population.</p><p><strong>Results: </strong>Out of 148 participants (<i>n</i> = 57, 38%) had colonized <i>candida</i>. None of the studied population had visible <i>Candida</i> lesions. However, <i>Candida</i> was found in the oral rinses without the subject presenting any lesions or issues caused by <i>Candida</i> (asymptomatic colonization). The most common prevalent OC among participants were <i>Candida</i> <i>albicans</i>, <i>Candida glabrata</i>, <i>Candida dubliniensis</i>, <i>Candida krusei</i>, <i>Candida tropicalis</i>, and <i>Candida parapsilosis</i> (<i>n</i> = 35, 61%; <i>n</i> = 8, 14%; <i>n</i> = 6, 10%; <i>n</i> = 5, 9%; <i>n</i> = 2, 4%; and <i>n</i> = 1, 2%) respectively. Diabetes, smoking, poor plaque, and gingival status were key potential risk factors that significantly associated with <i>candida</i>'s density and presence (<i>P</i> = 0.001, <i>P</i> = 0.001, <i>P</i> = 0.01, and <i>P</i> = 0.01) respectively. Disability status had no statistically significant effect on presence and density of <i>Candida</i>.</p><p><strong>Conclusion: </strong>The prevalence of OC is almost third of the studied population; thus, may provoke a need to develop preventive strategies to reduce the OC rate and establish solid treatment plans.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful endoscopic treatment of superficial esophageal cancer in a patient with esophageal variceal bleeding: A case report. 成功通过内窥镜治疗食管静脉曲张出血患者的浅表食管癌:病例报告。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6105
Li Xu, Shan-Shan Chen, Chao Yang, Hai-Jun Cao
{"title":"Successful endoscopic treatment of superficial esophageal cancer in a patient with esophageal variceal bleeding: A case report.","authors":"Li Xu, Shan-Shan Chen, Chao Yang, Hai-Jun Cao","doi":"10.12998/wjcc.v12.i27.6105","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6105","url":null,"abstract":"<p><strong>Background: </strong>The coexistence of esophageal variceal bleeding and superficial esophageal cancer (SEC) is relatively rare in clinical practice. Moreover, there have been few reports of SEC overlying esophageal varices (EVs). Herein, we report our successful use of endoscopic submucosal dissection (ESD), esophageal solitary venous dilatation (ESVD), and endoscopic injection sclerotherapy (EIS) to treat a 75-year-old man who was diagnosed with SEC coexisting with esophageal variceal bleeding.</p><p><strong>Case summary: </strong>A 75-year-old man was admitted to the hospital due to black stool for 4 days. The patient had a history of liver cancer, cirrhosis, and portal hypertension. Endoscopic examination revealed esophageal and gastric varicose veins, as well as esophageal carcinoma <i>in situ</i>. We first treated esophageal variceal bleeding by ESVD and EIS. One week later, ESD treatment was done, and the complete resection of early esophageal cancer was successfully completed <i>via</i> endoscopy. There were no postoperative complications, such as bleeding, infection, or perforation.</p><p><strong>Conclusion: </strong>The sequential treatment of ESVD, EIS, and ESD is an effective method for treating EVs with early esophageal cancer.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application effect of case management nursing based on patient safety in patients with prostate cancer. 基于患者安全的个案管理护理在前列腺癌患者中的应用效果。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6070
Ru Zhou, Chan-Ling Xu
{"title":"Application effect of case management nursing based on patient safety in patients with prostate cancer.","authors":"Ru Zhou, Chan-Ling Xu","doi":"10.12998/wjcc.v12.i27.6070","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6070","url":null,"abstract":"<p><strong>Background: </strong>Globally, prostate cancer has become a major threat to men's health, with an increasing incidence and causes serious effects on the quality and length of life of patients. Despite the rapid development of medical technology, which provides treatments, including surgery, radiotherapy, and endocrine therapy, the treatment of patients with prostate cancer, especially with endocrine therapy, has become a major challenge in clinical treatment owing to the lengthy course of treatment, side effects of drugs, and impact of the disease on the psychological and physiological functioning of the patient, producing poor treatment adherence and a decline in quality of life.</p><p><strong>Aim: </strong>To explore effects of nursing intervention prioritizing patient safety and case management in patients with prostate cancer undergoing endocrine therapy.</p><p><strong>Methods: </strong>Eighty patients with prostate cancer who received endocrine therapy at our hospital between January 2022 and January 2024 were divided into observation and control groups with 40 cases per group. The control group was treated using a routine nursing workflow while the observation group received case management nursing guidance prioritizing patient safety. Scores for anxiety and depression, prostate cancer symptoms, and quality of life and patient compliance and satisfaction were compared between the groups after three months of intervention.</p><p><strong>Results: </strong>After the nursing intervention, the anxiety and depression scores of the observation group were significantly lower than those of the control group (<i>P</i> < 0.05). The quality of life score, sexual function, and hormone function were significantly higher than those in the control group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Case management guidance based on patient safety effectively reduced anxiety and depression in patients undergoing endocrine therapy for prostate cancer and improved their quality of life, treatment compliance, and satisfaction.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deciphering the iron enigma: Navigating the complexities of iron metabolism in critical illness. 破解铁谜:探索危重病人铁代谢的复杂性。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6027
Anjali Mishra, Deven Juneja
{"title":"Deciphering the iron enigma: Navigating the complexities of iron metabolism in critical illness.","authors":"Anjali Mishra, Deven Juneja","doi":"10.12998/wjcc.v12.i27.6027","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6027","url":null,"abstract":"<p><p>Iron is a double-edged sword! Despite being essential for numerous physiological processes of the body, a dysregulated iron metabolism can result in tissue damage, exaggerated inflammatory response, and increased susceptibility to infection with certain pathogens that thrive in iron-rich environment. During sepsis, there is an alteration of iron metabolism, leading to increased transport and uptake into cells. This increase in labile iron may cause oxidative damage and cellular injury (ferroptosis) which progresses as the disease worsens. Critically ill patients are often complicated with systemic inflammation which may contribute to multiple organ dysfunction syndrome or sepsis, a common cause of mortality in intensive care unit. Originally, ferritin was known to play an important role in the hematopoietic system for its iron storage capacity. Recently, its role has emerged as a predictor of poor prognosis in chronic inflammation and critical illnesses. Apart from predicting the disease outcome, serum ferritin can potentially reflect disease activity as well.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular medicine in the 21st century: Embracing comprehensive vasculature evaluation and multidisciplinary treatment. 21 世纪的血管医学:全面的血管评估和多学科治疗。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6032
Yoram Chaiter, Daniel Lyon Fink, Yossy Machluf
{"title":"Vascular medicine in the 21<sup>st</sup> century: Embracing comprehensive vasculature evaluation and multidisciplinary treatment.","authors":"Yoram Chaiter, Daniel Lyon Fink, Yossy Machluf","doi":"10.12998/wjcc.v12.i27.6032","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6032","url":null,"abstract":"<p><p>The field of vascular medicine has undergone a profound transformation in the 21<sup>st</sup> century, transforming our approach to assessment and treatment. Atherosclerosis, a complex inflammatory disease that affects medium and large arteries, presents a major challenge for researchers and healthcare professionals. This condition, characterized by arterial plaque formation and narrowing, poses substantial challenges to vascular health at individual, national, and global scales. Its repercussions are far-reaching, with clinical outcomes including ischemic heart disease, ischemic stroke, and peripheral arterial disease-conditions with escalating global prevalence. Early detection of vascular changes caused by atherosclerosis is crucial in preventing these conditions, reducing morbidity, and averting mortality. This article underscored the imperative of adopting a holistic approach to grappling with the intricacies, trajectories, and ramifications of atherosclerosis. It stresses the need for a thorough evaluation of the vasculature and the implementation of a multidisciplinary treatment approach. By considering the entire vascular system, healthcare providers can explore avenues for prevention, early detection, and effective management of this condition, ultimately leading to improved patient outcomes. We discussed current practices and proposed new directions made possible by emerging diagnostic modalities and treatment strategies. Additionally, we considered healthcare expenditure, resource allocation, and the transformative potential of new innovative treatments and technologies.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When the vermiform appendix resembles a polyp: Be cautious of an intussuscepted appendix polypectomy. 当蚯蚓状阑尾类似息肉时:小心阑尾息肉切除术。
IF 1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-26 DOI: 10.12998/wjcc.v12.i27.6124
Raffaele Pellegrino, Antonietta Gerarda Gravina
{"title":"When the vermiform appendix resembles a polyp: Be cautious of an intussuscepted appendix polypectomy.","authors":"Raffaele Pellegrino, Antonietta Gerarda Gravina","doi":"10.12998/wjcc.v12.i27.6124","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i27.6124","url":null,"abstract":"<p><p>This article discusses a recently published case report on a rare instance of type IV appendiceal intussusception with a concurrent mucinous adenocarcinoma of the cecum in a young individual. The report highlights challenges in diagnosing appendiceal intussusception, emphasizing the importance of endoscopic expertise in preventing impulsive decisions such as inappropriate polypectomies. The rarity of the concurrent intussuscepted appendix and mucinous cecal cancer is underscored, prompting consideration of malignancy in appendiceal intussusception cases. Additionally, the report addresses the increasing incidence of early-onset colorectal cancer and the need for a revaluation of diagnostic paradigms in the context of evolving epidemiological trends. The awareness of potential misinterpretations and the imperative for further investigation into this rare condition are emphasized.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of perinatal factors on full-term low-birth-weight infants and construction of a predictive model. 围产期因素对足月低体重儿的影响及预测模型的构建。
IF 1.1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-16 DOI: 10.12998/wjcc.v12.i26.5901
Liang Xu,Xue-Juan Sheng,Lian-Ping Gu,Zu-Ming Yang,Zong-Tai Feng,Dan-Feng Gu,Li Gao
{"title":"Influence of perinatal factors on full-term low-birth-weight infants and construction of a predictive model.","authors":"Liang Xu,Xue-Juan Sheng,Lian-Ping Gu,Zu-Ming Yang,Zong-Tai Feng,Dan-Feng Gu,Li Gao","doi":"10.12998/wjcc.v12.i26.5901","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i26.5901","url":null,"abstract":"BACKGROUNDBeing too light at birth can increase the risk of various diseases during infancy.AIMTo explore the effect of perinatal factors on term low-birth-weight (LBW) infants and build a predictive model. This model aims to guide the clinical management of pregnant women's healthcare during pregnancy and support the healthy growth of newborns.METHODSA retrospective analysis was conducted on data from 1794 single full-term pregnant women who gave birth. Newborns were grouped based on birth weight: Those with birth weight < 2.5 kg were classified as the low-weight group, and those with birth weight between 2.5 kg and 4 kg were included in the normal group. Multiple logistic regression analysis was used to identify the factors influencing the occurrence of full-term LBW. A risk prediction model was established based on the analysis results. The effectiveness of the model was analyzed using the Hosmer-Leme show test and receiver operating characteristic (ROC) curve to verify the accuracy of the predictions.RESULTSAmong the 1794 pregnant women, there were 62 cases of neonatal weight < 2.5 kg, resulting in an LBW incidence rate of 3.46%. The factors influencing full-term LBW included low maternal education level [odds ratio (OR) = 1.416], fewer prenatal examinations (OR = 2.907), insufficient weight gain during pregnancy (OR = 3.695), irregular calcium supplementation during pregnancy (OR = 1.756), and pregnancy hypertension syndrome (OR = 2.192). The prediction model equation was obtained as follows: Logit (P) = 0.348 × maternal education level + 1.067 × number of prenatal examinations + 1.307 × insufficient weight gain during pregnancy + 0.563 × irregular calcium supplementation during pregnancy + 0.785 × pregnancy hypertension syndrome - 29.164. The area under the ROC curve for this model was 0.853, with a sensitivity of 0.852 and a specificity of 0.821. The Hosmer-Leme show test yielded χ 2 = 2.185, P = 0.449, indicating a good fit. The overall accuracy of the clinical validation model was 81.67%.CONCLUSIONThe occurrence of full-term LBW is related to maternal education, the number of prenatal examinations, weight gain during pregnancy, calcium supplementation during pregnancy, and pregnancy-induced hypertension. The constructed predictive model can effectively predict the risk of full-term LBW.","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142265227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multivariate analysis of oral mucosal ulcers during orthodontic treatment. 正畸治疗期间口腔黏膜溃疡的多变量分析。
IF 1.1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-16 DOI: 10.12998/wjcc.v12.i26.5868
Jing Chang,Xue Li
{"title":"Multivariate analysis of oral mucosal ulcers during orthodontic treatment.","authors":"Jing Chang,Xue Li","doi":"10.12998/wjcc.v12.i26.5868","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i26.5868","url":null,"abstract":"BACKGROUNDOrthodontic treatment can easily cause local soft tissue reactions in the oral cavity of patients under mechanical stress, leading to oral mucosal ulcers and affecting their quality of life. At present, only limited literature has explored the factors leading to oral ulcers in orthodontic treatment, and these research results are still controversial.AIMTo investigate the current status and related factors of oral mucosal ulcers during orthodontic treatment, aiming to provide a valuable reference for preventing this disease in clinical practice.METHODSA total of 587 patients who underwent orthodontic treatment at the Peking University School of Stomatology and Hospital of Stomatology between 2020 and 2022 were selected and allocated to an observation or control group according to the incidence of oral mucosal ulcers during orthodontic therapy. A questionnaire survey was constructed to collect patient data, including basic information, lifestyle and eating habits, treatment details, mental factors, and trace element levels, and a comparative analysis of this data was performed between the two groups.RESULTSA logistic regression model with oral ulcers as the dependent variable was established. The regression results showed that age (≥ 60 years: odds ratio [OR]: 6.820; 95% confidence interval [CI]: 2.226-20.893), smoking history (smoking: OR: 4.434; 95%CI: 2.527-7.782), toothbrush hardness (hard: OR: 2.804; 95%CI: 1.746-4.505), dietary temperature (hot diet: OR: 1.399; 95%CI: 1.220-1.722), treatment course (> 1 year: OR: 3.830; 95%CI: 2.203-6.659), and tooth brushing frequency (> 1 time per day: OR: 0.228; 95%CI: 0.138-0.377) were independent factors for oral mucosal ulcers (P < 0.05). Furthermore, Zn level (OR: 0.945; 95%CI: 0.927-0.964) was a protective factor against oral ulcers, while the SAS (OR: 1.284; 95%CI: 1.197-1.378) and SDS (OR: 1.322; 95%CI: 1.231-1.419) scores were risk factors.CONCLUSIONAge ≥ 60 years, smoking history, hard toothbrush, hot diet, treatment course for > 1 year, tooth brushing frequency of ≤ 1 time per day, and mental anxiety are independent risk factors for oral mucosal ulcers. Therefore, these factors should receive clinical attention and be incorporated into the development and optimization of preventive strategies for reducing oral ulcer incidence.","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142265340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of the intensive care unit activity scale in the early rehabilitation of patients after direct cardiac surgery. 重症监护室活动量表在心脏直视手术后患者早期康复中的应用研究。
IF 1.1 4区 医学
World Journal of Clinical Cases Pub Date : 2024-09-16 DOI: 10.12998/wjcc.v12.i26.5930
Li Wang,Jing-Ya Lu,Xiao-Xiao Ma,Lan-Ou Ma
{"title":"Study of the intensive care unit activity scale in the early rehabilitation of patients after direct cardiac surgery.","authors":"Li Wang,Jing-Ya Lu,Xiao-Xiao Ma,Lan-Ou Ma","doi":"10.12998/wjcc.v12.i26.5930","DOIUrl":"https://doi.org/10.12998/wjcc.v12.i26.5930","url":null,"abstract":"BACKGROUNDDirect cardiac surgery often necessitates intensive post-operative care, and the intensive care unit (ICU) activity scale represents a crucial metric in assessing and guiding early rehabilitation efforts to enhance patient recovery.AIMTo clarify the clinical application value of the ICU activity scale in the early recovery of patients after cardiac surgery.METHODSOne hundred and twenty patients who underwent cardiac surgery between September 2020 and October 2021 were selected and divided into two groups using the random number table method. The observation group was rated using the ICU activity scale and the corresponding graded rehabilitation interventions were conducted based on the ICU activity scale. The control group was assessed in accordance with the routine rehabilitation activities, and the postoperative rehabilitation indexes of the patients in both groups were compared (time of tracheal intubation, time of ICU admission, occurrence of complications, and activity scores before ICU transfer). The two groups were compared according to postoperative rehabilitation indicators (time of tracheal intubation, length of ICU stay, and occurrence of complications) and activity scores before ICU transfer.RESULTSIn the observation group, tracheal intubation time lasted for 18.30 ± 3.28 h and ICU admission time was 4.04 ± 0.83 d, which were significantly shorter than the control group (t-values: 2.97 and 2.038, respectively, P < 0.05). The observation group also had a significantly lower number of complications and adverse events compared to the control group (P < 0.05). Before ICU transfer, the observation group (6.7%) had few complications and adverse events than the control group (30.0 %), and this difference was statistically significant (P < 0.05). Additionally, the activity score was significantly higher in the observation (26.89 ± 0.97) compared to the control groups (22.63 ± 1.12 points) (t-value; -17.83, P < 0.05).CONCLUSIONImplementation of early goal-directed activities in patients who underwent cardiac surgery using the ICU activity scale can promote the recovery of cardiac function.","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142265230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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