{"title":"老年男性孤立性髓外浆细胞瘤模拟眼表鳞状瘤:1例报告。","authors":"Thilakraj Koppalu Lingaraju, Bijnya Birajita Panda, Madhusmita Sethy, Sri Lasya Achanta","doi":"10.12998/wjcc.v13.i26.108409","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Conjunctival plasmacytoma is an exceedingly uncommon form of extramedullary manifestation of multiple myeloma, with only a handful of cases reported so far.</p><p><strong>Case summary: </strong>A 66-year-old male of Indian origin with multiple myeloma presented with a 1-year history of progressive pink mass associated with itching in his left eye. Examination revealed a pinkish conjunctival mass with telangiectasia extending up to the temporal limbus, mimicking ocular surface squamous neoplasia. The patient underwent successful excision of the mass and amniotic membrane grafting. Histopathological examination after excision revealed plasma cell infiltration, confirming an unusual extramedullary manifestation of multiple myeloma. The patient was followed up for one year, with no evidence of recurrence.</p><p><strong>Conclusion: </strong>This case report highlights the importance of considering multiple myeloma in the differential diagnosis of ocular masses, particularly in patients with a known history of the disease. The presentation of a conjunctival mass in a patient with multiple myeloma is rare, but it is essential to recognize this possibility to ensure timely and appropriate management.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"108409"},"PeriodicalIF":1.0000,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336871/pdf/","citationCount":"0","resultStr":"{\"title\":\"Solitary extramedullary plasmacytoma mimicking ocular surface squamous neoplasia in an elderly male: A case report.\",\"authors\":\"Thilakraj Koppalu Lingaraju, Bijnya Birajita Panda, Madhusmita Sethy, Sri Lasya Achanta\",\"doi\":\"10.12998/wjcc.v13.i26.108409\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Conjunctival plasmacytoma is an exceedingly uncommon form of extramedullary manifestation of multiple myeloma, with only a handful of cases reported so far.</p><p><strong>Case summary: </strong>A 66-year-old male of Indian origin with multiple myeloma presented with a 1-year history of progressive pink mass associated with itching in his left eye. Examination revealed a pinkish conjunctival mass with telangiectasia extending up to the temporal limbus, mimicking ocular surface squamous neoplasia. The patient underwent successful excision of the mass and amniotic membrane grafting. Histopathological examination after excision revealed plasma cell infiltration, confirming an unusual extramedullary manifestation of multiple myeloma. The patient was followed up for one year, with no evidence of recurrence.</p><p><strong>Conclusion: </strong>This case report highlights the importance of considering multiple myeloma in the differential diagnosis of ocular masses, particularly in patients with a known history of the disease. The presentation of a conjunctival mass in a patient with multiple myeloma is rare, but it is essential to recognize this possibility to ensure timely and appropriate management.</p>\",\"PeriodicalId\":23912,\"journal\":{\"name\":\"World Journal of Clinical Cases\",\"volume\":\"13 26\",\"pages\":\"108409\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336871/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Clinical Cases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12998/wjcc.v13.i26.108409\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Clinical Cases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12998/wjcc.v13.i26.108409","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Solitary extramedullary plasmacytoma mimicking ocular surface squamous neoplasia in an elderly male: A case report.
Background: Conjunctival plasmacytoma is an exceedingly uncommon form of extramedullary manifestation of multiple myeloma, with only a handful of cases reported so far.
Case summary: A 66-year-old male of Indian origin with multiple myeloma presented with a 1-year history of progressive pink mass associated with itching in his left eye. Examination revealed a pinkish conjunctival mass with telangiectasia extending up to the temporal limbus, mimicking ocular surface squamous neoplasia. The patient underwent successful excision of the mass and amniotic membrane grafting. Histopathological examination after excision revealed plasma cell infiltration, confirming an unusual extramedullary manifestation of multiple myeloma. The patient was followed up for one year, with no evidence of recurrence.
Conclusion: This case report highlights the importance of considering multiple myeloma in the differential diagnosis of ocular masses, particularly in patients with a known history of the disease. The presentation of a conjunctival mass in a patient with multiple myeloma is rare, but it is essential to recognize this possibility to ensure timely and appropriate management.
期刊介绍:
The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.