World Journal of Clinical Cases最新文献

{"title":"Evaluation of the mental health of COVID-19 patients discharged from the intensive care unit.","authors":"Elif Sarac","doi":"10.12998/wjcc.v12.i33.6587","DOIUrl":"10.12998/wjcc.v12.i33.6587","url":null,"abstract":"<p><p>In this editorial, I address the mental health status of patients who have been discharged from intensive care units (ICUs) after battling coronavirus disease 2019 (COVID-19). An ICU admission is generally a stressful experience, and for severe COVID-19 survivors prolonged treatment in the ICU can lead to significant psychological consequences. These individuals may experience psychiatric distress, including symptoms such as insomnia, anxiety, depression, and even post-traumatic psychological issues. Research indicates that during the first 6 months to 1 year following an ICU stay, nearly one-third of survivors exhibit symptoms similar to those of depression and post-traumatic stress disorder. Several factors may have contributed to the development of depressive and anxious symptoms during the COVID-19 pandemic, particularly for those who underwent an ICU stay. The ICU environment itself is inherently stressful, filled with the constant noise of various medical devices. Studies have provided strong evidence that the prolonged need for ventilation support and the loss of freedom of movement are key factors in the development of psychological problems among COVID-19 patients who had been treated in the ICU.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6587-6590"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors and risk prediction model for mucocutaneous separation in enterostomy patients: A single center experience.","authors":"Yun Liu, Hong Li, Jin-Jing Wu, Jian-Hong Ye","doi":"10.12998/wjcc.v12.i33.6620","DOIUrl":"10.12998/wjcc.v12.i33.6620","url":null,"abstract":"<p><strong>Background: </strong>Mucocutaneous separation (MCS) is a common postoperative complication in enterostomy patients, potentially leading to significant morbidity. Early identification of risk factors is crucial for preventing this condition. However, predictive models for MCS remain underdeveloped.</p><p><strong>Aim: </strong>To construct a risk prediction model for MCS in enterostomy patients and assess its clinical predictive accuracy.</p><p><strong>Methods: </strong>A total of 492 patients who underwent enterostomy from January 2019 to March 2023 were included in the study. Patients were divided into two groups, the MCS group (<i>n</i> = 110), and the non-MCS (<i>n</i> = 382) based on the occurrence of MCS within the first 3 weeks after surgery. Univariate and multivariate analyses were used to identify the independent predictive factors of MCS and the model constructed. Receiver operating characteristic curve analysis was used to assess the model's performance.</p><p><strong>Results: </strong>The postoperative MCS incidence rate was 22.4%. Suture dislodgement (<i>P</i> < 0.0001), serum albumin level (<i>P</i> < 0.0001), body mass index (BMI) (<i>P</i> = 0.0006), hemoglobin level (<i>P</i> = 0.0409), intestinal rapture (<i>P</i> = 0.0043), incision infection (<i>P</i> < 0.0001), neoadjuvant therapy (<i>P</i> = 0.0432), stoma site (<i>P</i> = 0.0028) and elevated intra-abdominal pressure (<i>P</i> = 0.0395) were potential predictive factors of MCS. Suture dislodgement [<i>P</i> < 0.0001, OR: 28.0075 95%CI: (11.0901-82.1751)], serum albumin level (<i>P</i> = 0.0008, OR: 0.3504, 95%CI: [0.1902-0.6485]), BMI [<i>P</i> = 0.0045, OR: 2.1361, 95%CI: (1.2660-3.6235)], hemoglobin level [<i>P</i> = 0.0269, OR: 0.5164, 95%CI: (0.2881-0.9324)], intestinal rapture [<i>P</i> = 0.0351, OR: 3.0694, 95%CI: (1.0482-8.5558)], incision infection [<i>P</i> = 0.0179, OR: 0.2885, 95%CI: (0.0950-0.7624)] and neoadjuvant therapy [<i>P</i> = 0.0112, OR: 1.9769, 95%CI: (1.1718-3.3690)] were independent predictive factors and included in the model. The model had an area under the curve of 0.827 and good clinical utility on decision curve analysis.</p><p><strong>Conclusion: </strong>The mucocutaneous separation prediction model constructed in this study has good predictive performance and can provide a reference for early warning of mucocutaneous separation in enterostomy patients.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6620-6628"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating the health belief model into health education programs in a clinical setting.","authors":"Bee Sung Kam, Sang Yeoup Lee","doi":"10.12998/wjcc.v12.i33.6660","DOIUrl":"10.12998/wjcc.v12.i33.6660","url":null,"abstract":"<p><p>The article demonstrates that health belief model (HBM)-based health education in hypertensive patients effectively improves blood pressure control and medication adherence at 3 months and 6 months. The HBM addresses perceived barriers, benefits, susceptibility, severity, and self-efficacy, leading to better health behaviors. HBM-based education has been effective in various contexts, including managing chronic diseases, promoting cancer screenings, and preventing infectious diseases. However, the model has limitations, such as cultural applicability and addressing complex health behaviors influenced by environmental factors. Future research should integrate HBM with other theories and conduct longitudinal studies to assess long-term impacts. Despite these limitations, HBM-based education significantly improves patient outcomes, highlighting its potential in health education and promotion when appropriately adapted and implemented. This reinforces the model's value in designing effective health interventions and advancing public health.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6660-6663"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of sarcopenia and frailty in the management of elderly patients with acute appendicitis.","authors":"Pietro Fransvea, Maria Michela Chiarello, Valeria Fico, Maria Cariati, Giuseppe Brisinda","doi":"10.12998/wjcc.v12.i33.6580","DOIUrl":"10.12998/wjcc.v12.i33.6580","url":null,"abstract":"<p><p>In developed countries, the average life expectancy has been increasing and is now well over 80 years. Increased life expectancy is associated with an increased number of emergency surgical procedures performed in later age groups. Acute appendicitis is one of the most common surgical diseases, with a lifetime risk of 8%. A growing incidence of acute appendicitis has been registered in the elderly population and in the oldest groups (> 80 years). Among patients > 50-year-old who present to the emergency department for acute abdominal pain, 15% have acute appendicitis. In these patients, emergency surgery for acute appendicitis is challenging, and some important aspects must be considered. In the elderly, surgical treatment outcomes are influenced by sarcopenia. Sarcopenia must be considered a precursor of frailty, a risk factor for physical function decline. Sarcopenia has a negative impact on both elective and emergency surgery regarding mortality and morbidity. Aside from morbidity and mortality, the most crucial outcomes for older patients requiring emergency surgery are reduction in function decline and preoperative physical function maintenance. Therefore, prediction of function decline is critical. In emergency surgery, preoperative interventions are difficult to implement because of the narrow time window before surgery. In this editorial, we highlight the unique aspects of acute appendicitis in elderly patients and the influence of sarcopenia and frailty on the results of surgical treatment.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6580-6586"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Journey to diagnosis: An unfinished exploration of IgG4-related sclerosing cholangitis.","authors":"Ming-Xing Liang, Ya Chen, Ya He, Yi-Huai He","doi":"10.12998/wjcc.v12.i33.6608","DOIUrl":"10.12998/wjcc.v12.i33.6608","url":null,"abstract":"<p><p>IgG4-related sclerosing cholangitis (IgG4-SC) is an inflammatory disease that leads to bile duct stricture, characterized by the infiltration of IgG4-positive plasma cells into the bile duct wall, thickening of the bile duct wall, and narrowing of the lumen. The differential diagnosis of IgG4-SC mainly includes primary sclerosing cholangitis, cholangiocarcinoma, and pancreatic cancer. IgG4-SC is often associated with autoimmune pancreatitis and can be accurately diagnosed based on clinical diagnostic criteria. However, isolated IgG4-SC is difficult to distinguish from biliary tumors. Given the significant differences in biological behavior, treatment, and prognosis between these diseases, accurately identifying isolated IgG4-SC has very important clinical significance.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6608-6612"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexner's legacy and the future of medical education: Embracing challenge and opportunity.","authors":"Quzhen Zeren, Yan Zeng, Jun-Wen Zhang, Jian Yang","doi":"10.12998/wjcc.v12.i33.6650","DOIUrl":"10.12998/wjcc.v12.i33.6650","url":null,"abstract":"<p><p>This editorial comments on the article by Alzerwi. We focus on the development course, present challenges, and future perspectives of medical education. Modern medical education is gradually undergoing significant and profound changes worldwide. The emergence of new ideas, methodologies, and techniques has created opportunities for medical education developments and brought new concerns and challenges, ultimately promoting virtuous progress in medical education reform. The sustainable development of medical education needs joint efforts and support from governments, medical colleges, hospitals, researchers, administrators, and educators.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6650-6654"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary diabetes due to different etiologies: A problem worthy of attention.","authors":"Zhao Wei, Xue-Jian Wang","doi":"10.12998/wjcc.v12.i33.6647","DOIUrl":"10.12998/wjcc.v12.i33.6647","url":null,"abstract":"<p><p>There are many factors in the occurrence of diabetes, which can result in insufficient insulin secretion and insulin receptor resistance. Including pituitary tumors, can also lead to the occurrence of diabetes, if the primary disease can not be well controlled in time, such secondary diabetes control is more difficult. In the process of clinical diagnosis and treatment, these factors need to be taken into account, timely detection and treatment of primary diseases, so as to reduce the possibility of clinical missed diagnosis.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6647-6649"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prothrombotic state and thrombotic events in COVID-19 pandemic period, including portal vein and splenic artery thromboses.","authors":"Ozgur Karcioglu, Canan Akman, Göksu Afacan Ozturk","doi":"10.12998/wjcc.v12.i33.6595","DOIUrl":"10.12998/wjcc.v12.i33.6595","url":null,"abstract":"<p><p>This editorial article is intended to perform a discussion on the manuscript entitled \"Simultaneous portal vein thrombosis and splenic vein thrombosis in a COVID-19 patient: A case report and review of literature\" written by Abramowitz <i>et al</i>. The article focuses on the diagnostic processes in a 77-year-old-male patient with a simultaneous portal vein and splenic artery thrombosis accompanying coronavirus disease 2019 (COVID-19). The authors postulated that splanchnic thrombosis should be on the list of differential diagnoses in a patient presenting with abdominal pain in presence of a COVID-19 infection. The tendency for venous and arterial thrombosis in COVID-19 patients is encountered, largely attributed to hypercoagulopathy. In general, venous thromboembolism mostly manifest as deep vein thrombosis (DVT), pulmonary embolism (PE) or catheter-related thromboembolic events. Acute PE, DVT, cerebrovascular events and myocardial infarction are seen as the most common thromboembolic complications in COVID-19 patients. COVID-19-associated hemostatic abnormalities include mild thrombocytopenia and increased D-dimer level. Similar to other coagulopathies, the treatment of the underlying condition is the mainstay. Addition of antiplatelet agents can be considered in critically ill patients at low bleeding risk, not on therapeutic anticoagulation, and receiving gastric acid suppression Early administration of antithrombotic drugs will have a beneficial effect in both the prevention and treatment of thrombotic events, especially in non-ambulatory patients. Low molecular weight heparin (LMWH) should be started if there is no contraindication, including in non-critical patients who are at risk of hospitalization LMWH (enoxaparin) is preferred to standard heparin.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6595-6603"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting nuclear factor erythroid 2-related factor 2-regulated ferroptosis to treat nervous system diseases.","authors":"Ye-Qi Huang, Zheng-Wei Huang, Xue-Juan Zhang","doi":"10.12998/wjcc.v12.i33.6655","DOIUrl":"10.12998/wjcc.v12.i33.6655","url":null,"abstract":"<p><p>By critically examining the work, we conducted a comprehensive bibliometric analysis on the role of nuclear factor erythroid 2-related factor 2 (NRF2) in nervous system diseases. We also proposed suggestions for future bibliometric studies, including the integration of multiple websites, analytical tools, and analytical approaches, The findings presented provide compelling evidence that ferroptosis is closely associated with the therapeutic challenges of nervous system diseases. Targeted modulation of NRF2 to regulate ferroptosis holds substantial potential for effectively treating these diseases. Future NRF2-related research should not only focus on discovering new drugs but also on designing rational drug delivery systems. In particular, nanocarriers offer substantial potential for facilitating the clinical translation of NRF2 research and addressing existing issues related to NRF2-related drugs.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6655-6659"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements and challenges in gastrointestinal imaging.","authors":"Eun Jeong Gong, Chang Seok Bang","doi":"10.12998/wjcc.v12.i33.6591","DOIUrl":"10.12998/wjcc.v12.i33.6591","url":null,"abstract":"<p><p>A recent review by Gulinac <i>et al</i>, provides an in-depth analysis of current clinical issues and challenges in gastrointestinal imaging. This editorial highlights the advancements in imaging techniques, including the integration of artificial intelligence and functional imaging modalities, and discusses the ongoing relevance of traditional nuclear medicine tests. The future of gastrointestinal imaging looks promising, with continuous improvements in resolution, enhanced ability to analyze color and texture beyond visual diagnosis, faster image processing, and the application of molecular imaging and nanoparticles expected to enhance diagnostic accuracy and clinical outcomes.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 33","pages":"6591-6594"},"PeriodicalIF":1.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}