World Journal of Clinical Cases最新文献

{"title":"Potential role of large language models and personalized medicine to innovate cardiac rehabilitation.","authors":"Rishith Mishra, Hersh Patel, Aleena Jamal, Som Singh","doi":"10.12998/wjcc.v13.i19.98095","DOIUrl":"10.12998/wjcc.v13.i19.98095","url":null,"abstract":"<p><p>Cardiac rehabilitation is a crucial multidisciplinary approach to improve patient outcomes. There is a growing body of evidence that suggests that these programs contribute towards reducing cardiovascular mortality and recurrence. Despite this, cardiac rehabilitation is underutilized and adherence to these programs has been a demonstrated barrier in achieving these outcomes. As a result, there is a growing focus on innovating these programs, especially from the standpoint of digital health and personalized medicine. This editorial discusses the possible roles of large language models, such as their role in ChatGPT, in further personalizing cardiac rehabilitation programs through simplifying medical jargon and employing motivational interviewing techniques, thus boosting patient engagement and adherence. However, these possibilities must be further investigated in the clinical literature. Likewise, the integration of large language models in cardiac rehabilitation will be challenging in its nascent stages to ensure accurate and ethical information delivery.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 19","pages":"98095"},"PeriodicalIF":1.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected finding of cholecystogastric fistula in a patient undergoing laparoscopic cholecystectomy: A case report.","authors":"Sabtain Ali, Ayyub Anjum, Abdul Rauf Khalid, Muhammad Akbar Sultan, Safia Noor, Abdulqadir J Nashwan","doi":"10.12998/wjcc.v13.i19.104148","DOIUrl":"10.12998/wjcc.v13.i19.104148","url":null,"abstract":"<p><strong>Background: </strong>Gallbladder stones are a common occurrence, with a prevalence of approximately 10% in the Pakistani population. A rare but potentially fatal complication of gallstones is cholecystogastric fistulas. The underlying mechanism involves chronic inflammation due to cholelithiasis, causing gradual erosion and eventually leading to fistula formation.</p><p><strong>Case summary: </strong>We present a rare case of a cholecystogastric fistula in a 40-year-old female patient, successfully managed with an open surgical approach. The patient initially presented with a 6-month history of intermittent epigastric pain, nausea, and vomiting, which worsened over time. Laboratory investigations and abdominal ultrasound confirmed cholelithiasis, and laparoscopic cholecystectomy was planned. However, intraoperative findings revealed a cholecystogastric fistula, a rare complication of chronic gallstone disease. Given the dense adhesions between the gallbladder and the stomach, the procedure was converted to an open surgery. The fistula was divided, and a cholecystectomy was performed, along with primary repair of the gastric defect using a double-layer suture and reinforcement with an omental patch. The patient recovered uneventfully and was discharged on the third postoperative day.</p><p><strong>Conclusion: </strong>This case highlights the importance of considering cholecystogastric fistula in patients with vague gastrointestinal symptoms and chronic cholelithiasis. The report discusses diagnostic challenges, surgical approaches, and a review of the current literature on managing such rare but serious complications of gallstones.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 19","pages":"104148"},"PeriodicalIF":1.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain and scalp metastasis of cervical cancer in a patient with human immunodeficiency virus infection: A case report.","authors":"Hui-Qiong Huang, Feng-Ming Gong, Chun-Tang Sun, Yu Xuan, Lin Li","doi":"10.12998/wjcc.v13.i19.103946","DOIUrl":"10.12998/wjcc.v13.i19.103946","url":null,"abstract":"<p><strong>Background: </strong>Cervical cancer is the most commonly diagnosed cancer worldwide and the most common cancer in females living with human immunodeficiency virus (HIV). Cervical cancer is classified as an acquired immune deficiency syndrome-defining disease. Brain metastases (BMs) from cervical cancer are extremely rare, with an incidence rate of approximately 0.63%, and there is limited information on optimal treatment protocols and patient outcomes. Since brain lesions are sequestered behind the blood-brain barrier, multimodal treatment approaches are crucial to help improve the prognosis of cervical cancer in patients with BMs who are also living with HIV.</p><p><strong>Case summary: </strong>A 42-year-old Chinese female with HIV infection was diagnosed with stage IIIC1r cervical cancer in March 2022 based on the International Federation of Gynecology and Obstetrics system. Fourteen months after undergoing the initial treatment with concurrent chemotherapy and radiotherapy in January 2024, the patient presented to a local hospital with a severe explosive headache. The patient underwent craniotomy and postoperative pathological examination confirmed metastasis of cervical squamous cell carcinoma to the brain on February 1, 2024. Following surgery, the patient received external beam radiotherapy for the metastatic lesions. The patient has been under observation for 7 months with no evidence of tumor recurrence.</p><p><strong>Conclusion: </strong>Females living with HIV are more than three times more likely to be diagnosed with cervical cancer. Due to the scarcity of cervical cancer BMs, therapeutic protocol experience is limited. In addition to the existence of the blood-brain barrier, the treatment of cervical cancer BMs appears to be exceptionally complex, and a multi-modal treatment approach consisting of chemotherapy, surgery, and radiation may help prolong patients' life. For females living with HIV, antiretroviral therapy should be prioritized, as recommended by the Center for Disease Control in China. An intact immune system and a high CD4⁺ count are positive indicators of treatment response and tumor reduction. The overall survival of patients with cervical cancer after brain metastasis is approximately 3-5 months. However, owing to multimodal therapy and the use of antiretroviral therapy, the patient reported in this case showed no signs of recurrence after prolonged follow-up.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 19","pages":"103946"},"PeriodicalIF":1.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative approaches to managing chronic multimorbidity: A multidisciplinary perspective.","authors":"Haewon Byeon","doi":"10.12998/wjcc.v13.i19.102484","DOIUrl":"10.12998/wjcc.v13.i19.102484","url":null,"abstract":"<p><p>The rising prevalence of chronic multimorbidity poses substantial challenges to healthcare systems, necessitating the development of innovative management strategies to optimize patient care and system efficiency. The study by Fontalba-Navas <i>et al</i> investigates the implementation of a novel high complexity unit (HCU) specifically designed to improve the management of patients with chronic complex conditions. By adopting a multidisciplinary approach, the HCU aims to provide comprehensive, patient-centered care that enhances health outcomes and alleviates the strain on traditional hospital services. Utilizing a longitudinal analysis of data from the Basic Minimum Data Set, this study compares hospitalization metrics among the HCU, Internal Medicine, and other departments within a regional hospital throughout 2022. The findings reveal that the HCU's integrated care model significantly reduces readmission rates and boosts patient satisfaction compared to conventional care practices. The study highlights the HCU's potential as a replicable model for managing chronic multimorbidity, emphasizing its effectiveness in minimizing unnecessary hospitalizations and enhancing the overall quality of patient care. This innovative approach not only addresses the complexities associated with chronic multimorbid conditions but also offers a sustainable framework for healthcare systems confronting similar challenges.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 19","pages":"102484"},"PeriodicalIF":1.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total adenosine deaminase cases as an inflammatory biomarker of pleural effusion syndrome.","authors":"Bernardo Henrique Ferraz Maranhão, Cyro Teixeira da Silva Junior, Jorge Luiz Barillo, Joeber Bernardo Soares Souza, Patricia Siqueira Silva, Roberto Stirbulov","doi":"10.12998/wjcc.v13.i19.101850","DOIUrl":"10.12998/wjcc.v13.i19.101850","url":null,"abstract":"<p><strong>Background: </strong>Although inflammatory diseases commonly affect the pleura and pleural space, their mechanisms of action remain unclear. The presence of several mediators emphasizes the concept of pleural inflammation. Adenosine deaminase (ADA) is an inflammatory mediator detected at increased levels in the pleural fluid.</p><p><strong>Aim: </strong>To determine the role of total pleural ADA (P-ADA) levels in the diagnosis of pleural inflammatory diseases.</p><p><strong>Methods: </strong>157 patients with inflammatory pleural effusion (exudates, <i>n</i> = 124, 79%) and non-inflammatory pleural effusion (transudates, <i>n</i> = 33, 21%) were included in this observational retrospective cohort study. The P-ADA assay was tested using a kinetic technique. The performance of the model was evaluated using the area under the receiver operating characteristic (ROC) curve (AUC). The ideal cutoff value for P-ADA in pleural inflammation was determined using the Youden index in the ROC curve.</p><p><strong>Results: </strong>The transudates included congestive heart failure (<i>n</i> = 26), cirrhosis of the liver with ascites (<i>n</i> = 3), chronic renal failure (<i>n</i> = 3), and low total protein levels (<i>n</i> = 1). The exudate cases included tuberculosis (<i>n</i> = 44), adenocarcinoma (<i>n</i> = 37), simple parapneumonic effusions (<i>n</i> = 15), complicated parapneumonic effusions/empyema (<i>n</i> = 8), lymphoma (<i>n</i> = 7), and other diseases (<i>n</i> = 13). The optimal cutoff value of P-ADA was ≥ 9.00 U/L. The diagnostic parameters as sensitivity, specificity, positive and negative predictive values, positive and negative likelihood values, odds ratio, and accuracy were 77.69 (95%CI: 69.22-84.75); 68.75 (95%CI: 49.99-83.88); 90.38 and 44.90 (95%CI: 83.03-95.29; 30.67-59.77); 2.48 and 0.32 (95%CI: 2.21-11.2; 0.27-0.51); 7.65 (95%CI: 0.78-18.34), and 75.82 (95%CI: 68.24-82.37), respectively (<i>χ²</i> = 29.51, <i>P</i> = 0.00001). An AUC value of 0.8107 (95%CI: 0.7174-0.8754; <i>P</i> = 0.0000) was clinically useful. The Hosmer-Lemeshow test showed excellent discrimination.</p><p><strong>Conclusion: </strong>P-ADA biomarker has high diagnostic performance for pleural inflammatory exudates.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 19","pages":"101850"},"PeriodicalIF":1.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent invasive ductal carcinoma and ductal carcinoma <i>in situ</i> arising inside and outside a breast hamartoma: A case report.","authors":"Lai Wei, Zhe Tian, Zhi-Yong Wang, Wei-Jia Liu, Hong-Bo Li, Ying Zhang","doi":"10.12998/wjcc.v13.i18.101882","DOIUrl":"10.12998/wjcc.v13.i18.101882","url":null,"abstract":"<p><strong>Background: </strong>Breast hamartomas are rare benign breast tumors, with an incidence rate of 0.8%-4.8%. Further, the coexistence of hamartomas and carcinoma is also uncommon. Our case report presents a unique instance where invasive ductal carcinoma (IDC) and ductal carcinoma <i>in situ</i> were found both inside and outside a breast hamartoma. This is the second case reported in the literature.</p><p><strong>Case summary: </strong>A 51-year-old woman presented with a 6.0 cm breast tumor on mammography and ultrasound, with suspicious areas indicative of malignant transformation. Biopsy of the suspicious area confirmed IDC with intraductal carcinoma. Breast magnetic resonance imaging showed typical hamartoma changes with irregular areas of abnormal enhancement both inside and outside. A breast-conserving surgery was performed, and postoperative pathology confirmed mammary hamartoma, concurrent with IDC and intraductal carcinoma occurring both inside and outside the hamartoma. Subsequently, appropriate adjuvant therapy was initiated. Currently, the patient is in good condition. Breast cancer may be located both inside and outside the ipsilateral mammary hamartoma, which is difficult to detect preoperatively, especially when there is a focus of intraductal carcinoma, requiring accurate assessment of the tumor extent by modern imaging techniques. Early detection of the coexistence of cancer is clinically important as it can alter patient management.</p><p><strong>Conclusion: </strong>This case emphasizes the importance of modern imaging techniques in accurately evaluating mammary hamartomas associated with malignancies prior to surgery.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 18","pages":"101882"},"PeriodicalIF":1.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporary bilateral uterine artery occlusion in the control of hemorrhage: A case report and review of literature.","authors":"Yu-Liang Song, Chun-Feng Wang","doi":"10.12998/wjcc.v13.i18.101309","DOIUrl":"10.12998/wjcc.v13.i18.101309","url":null,"abstract":"<p><strong>Background: </strong>Intramural pregnancy is rare, with an unclear etiology and pathophysiology. Surgical, medical, and expectant management options are available for this condition. However, most reported cases are managed surgically. Despite the risks of massive intraoperative bleeding and acute and long-term complications, uterine artery embolization is often selected. Temporary occlusion of the bilateral uterine arteries during surgery is associated with fewer complications.</p><p><strong>Case summary: </strong>We reported the case of a patient who was diagnosed with intramural pregnancy approximately one month after medical abortion. We performed laparoscopic resection with hysteroscopy. Since the lesion had abundant blood flow, we temporarily blocked the bilateral uterine arteries to prevent massive intraoperative bleeding. The surgical process went smoothly. The postoperative course was uneventful.</p><p><strong>Conclusion: </strong>Temporary occlusion of the bilateral uterine arteries in the treatment of intramural pregnancy may prevent excessive uterine bleeding during surgery.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 18","pages":"101309"},"PeriodicalIF":1.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory Crohn's disease complicated with Guillain-Barré syndrome: A case report.","authors":"A-Niu Liu, Jia-Yi Yang, Xing-Yu Chen, Shan-Shan Wu, Se-Niu Ji Zhi, Shu-Mei Zheng","doi":"10.12998/wjcc.v13.i18.103618","DOIUrl":"10.12998/wjcc.v13.i18.103618","url":null,"abstract":"<p><strong>Background: </strong>Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory gastrointestinal disorders, including Crohn's disease (CD) and ulcerative colitis, with uncertain etiologies. The natural course of IBD can be accompanied by extraintestinal manifestations involving the skin, mucous membranes, musculoskeletal structures, eyes, cardiovascular system and nervous system. Guillain-Barré syndrome (GBS) is a type of peripheral neuropathy. However, the etiology and pathogenesis of IBD combined with GBS are unclear, and only a few clinical cases have been reported. Here, we report a case of refractory CD complicated by GBS and review the previous literature to improve the understanding of these diseases.</p><p><strong>Case summary: </strong>A 34-year-old man had a 9-year history of refractory CD. He became unresponsive to multiple drugs and experienced recurrent intestinal fistulas. After several abdominal surgeries and treatment with ustekinumab, he achieved clinical remission. Unfortunately, he developed GBS during maintenance treatment with ustekinumab. According to previous reports, in some patients with IBD combined with GBS, GBS may be a comorbidity, an extraintestinal manifestation of IBD, or an adverse reaction to IBD therapeutic drugs. After a comprehensive evaluation, we suspected that GBS might have been a comorbidity in this patient. To avoid fatal disease relapse after medication discontinuation, we concluded that ustekinumab should not be withdrawn. On the basis of a joint decision between doctors and the patient, we decided to continue maintenance treatment with ustekinumab along with intravenous immunoglobulin, dexamethasone and traditional Chinese medicine acupuncture, which resulted in a steady improvement in his GBS symptoms and sustained remission of CD.</p><p><strong>Conclusion: </strong>When IBD is complicated by a neurological disease, it is first necessary to analyze the patient's condition and then choose the corresponding treatment strategy. If the neurological disease is a specific comorbidity, treatment of both IBD and the comorbid disease should be considered. For IBD patients with extraintestinal manifestations involving the nervous system, neurological manifestations tend to resolve when the active IBD is controlled. When an adverse drug reaction is suspected, the medication should be discontinued, and symptomatic treatment should be administered.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 18","pages":"103618"},"PeriodicalIF":1.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Birt-Hogg-Dubé syndrome - a rare genetic disorder complicated by pneumothorax: A case report.","authors":"Meng-Zhen Li, Jun Deng","doi":"10.12998/wjcc.v13.i18.100610","DOIUrl":"10.12998/wjcc.v13.i18.100610","url":null,"abstract":"<p><strong>Background: </strong>Birt-Hogg-Dubé (BHD) syndrome is a rare genetic disorder associated with mutations in the <i>BHD</i> gene, which can manifest symptoms at any age, including dermatological and pulmonary complications, as well as renal tumors. This study presents a case of a BHD patient who experienced spontaneous pneumothorax, aiming to enhance the understanding of this syndrome.</p><p><strong>Case summary: </strong>A 42-year-old female patient presented with left-sided chest pain and tightness lasting three days. Chest computed tomography scans revealed left-sided pneumothorax and multiple pulmonary bullae. Physical examination indicated decreased vocal fremitus and tympanic percussion on the left side. A thorough family history revealed a pattern of pulmonary disorders, including emphysema, spontaneous pneumothorax, and lung cancer among relatives. Genetic testing identified a heterozygous frameshift mutation in the <i>FLCN</i> gene at the 17p11.2 locus. Based on the clinical presentation, imaging findings, family history, and genetic results, the patient was suspected to have BHD syndrome.</p><p><strong>Conclusion: </strong>We present a case of a heterozygous mutation in the <i>FLCN</i> gene in a patient with BHD syndrome, aiming to review the associated clinical characteristics and genetic mechanisms of this condition. This case serves as a reference point to offer insights into the diagnosis of multiple pulmonary cysts and spontaneous pneumothorax of unknown etiology in clinical practice.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 18","pages":"100610"},"PeriodicalIF":1.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal changes in computed tomography findings of a persimmon bezoar: A case report.","authors":"Masaya Iwamuro, Tomoki Yoshikawa, Tomohiro Kamio, Shoichiro Hirata, Katsunori Matsueda, Daisuke Kametaka, Motoyuki Otsuka","doi":"10.12998/wjcc.v13.i18.103426","DOIUrl":"10.12998/wjcc.v13.i18.103426","url":null,"abstract":"<p><strong>Background: </strong>Gastric bezoars are masses of indigestible material that accumulate in the stomach, causing nausea, abdominal pain, and vomiting. Persimmon bezoars (diospyrobezoars), which comprise tannins and fibers from persimmons, are relatively rare but may cause significant gastric complications, including gastric outlet obstruction or ileus. Although computed tomography (CT) is a useful imaging tool, diagnosing bezoars can be challenging because their density is similar to that of food debris and gastric content.</p><p><strong>Case summary: </strong>Here, we report the case of a 72-year-old woman with a persimmon bezoar that was diagnosed using serial CT imaging and confirmed by endoscopy. CT performed over several months revealed changes in the internal structure and density of the bezoar, suggesting progressive hardening. The patient had a history of a partial gastrectomy and excessive persimmon consumption, both of which are risk factors for bezoar formation. Endoscopic fragmentation of the bezoar successfully resolved symptoms.</p><p><strong>Conclusion: </strong>Gastric bezoars, particularly persimmon bezoars, present diagnostic challenges because of their variable imaging characteristics. Serial CT can document temporal changes in bezoar density, potentially reflecting changes in hardness. Early diagnosis and endoscopic treatment are essential for effective management, particularly in patients with predisposing factors. This case underscores the importance of considering bezoars in the differential diagnosis of gastric masses, and highlights the value of CT for monitoring changes in bezoar characteristics over time.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 18","pages":"103426"},"PeriodicalIF":1.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}