World Journal of Clinical Cases最新文献

{"title":"Human papillomavirus associated serous carcinoma of the uterine cervix in a patient with long-term survival: A case report.","authors":"Hui-Qiong Huang, Lu Yang, Qing-Li Li, Chun-Tang Sun, Feng-Ming Gong","doi":"10.12998/wjcc.v13.i22.104643","DOIUrl":"10.12998/wjcc.v13.i22.104643","url":null,"abstract":"<p><strong>Background: </strong>Serous carcinoma of the uterine cervix (USCC) represents a rare subtype of cervical adenocarcinoma, classified into human papillomavirus (HPV)-independent and HPV-associated types. It is characterized by high invasiveness and poor prognosis, with limited global reports on this condition.</p><p><strong>Case summary: </strong>A 58-year-old Chinese woman presented with painless vaginal bleeding after sexual intercourse, which appeared as droplets. HPV testing and histopathological analysis confirmed the diagnosis of HPV-associated primary serous carcinoma of the USCC. The patient underwent radical hysterectomy and was diagnosed with primary serous carcinoma of the uterine cervix, stage III C2 (FIGO 2018). A multimodal treatment approach, including surgery, radiotherapy, and chemotherapy, was administered. After additional concurrent chemoradiotherapy and three cycles of chemotherapy, the patient showed no evidence of disease progression and achieved long-term survival for 53 months.</p><p><strong>Conclusion: </strong>USCC is a rare and aggressive malignancy. Upon diagnosis, multimodal treatment strategies, including surgery, radiotherapy, and chemotherapy, can effectively prolong patient survival and improve prognosis.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"104643"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenosine deaminase in pleural effusion: Bridging diagnosis and the pathophysiology of inflammation.","authors":"Dan-Dan Shi, Ju Tian, Jing Ding","doi":"10.12998/wjcc.v13.i22.106925","DOIUrl":"10.12998/wjcc.v13.i22.106925","url":null,"abstract":"<p><p>This editorial underscores the importance of Maranhão <i>et al</i>'s study, which investigates pleural adenosine deaminase (P-ADA) as a biomarker for inflammatory pleural effusions. Despite advances in imaging, distinguishing between inflammatory and non-inflammatory causes of pleural effusion remains a diagnostic challenge. The authors conducted a rigorous retrospective cohort analysis of 157 patients (124 with inflammatory exudates and 33 with non-inflammatory transudates), establishing a robust cutoff value of P-ADA ≥ 9.00 U/L for diagnosing inflammatory diseases using receiver operating characteristic curve analysis and internal statistical calibration. This is the first study to define a standardized P-ADA threshold in a Brazilian cohort, addressing previous inconsistencies in cutoff values. Furthermore, the authors delved into the pathophysiological mechanisms underlying elevated P-ADA, linking it to purinergic signaling pathways and immune cell activation, particularly emphasizing the role of ADA2 isoforms in macrophages and lymphocytes. Their findings support P-ADA as a non-invasive, cost-effective biomarker for early diagnosis, treatment stratification, and minimizing the need for invasive procedures such as thoracentesis. This has particular relevance in resource-limited settings, where streamlined diagnostics can reduce healthcare costs and improve patient outcomes. Future studies must prioritize global validation, explore the integration of adenosine deaminase with additional biomarkers (<i>e.g</i>., interleukin 6, C-reactive protein), and support the development of point-of-care technologies.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"106925"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embedding narrative medicine in primary healthcare: Exploration and practice from a medical humanities perspective.","authors":"Ning-Jia Lei, Deep K Vaishnani, Mohmmad Shaheen, Haniah Pisheh, Jing Zeng, Fu-Rong Ying, Qiu-Qin Yang, Cong-Ying Wang, Jun Ma, Jing-Ye Pan, Ning-Jian Hou","doi":"10.12998/wjcc.v13.i22.105684","DOIUrl":"10.12998/wjcc.v13.i22.105684","url":null,"abstract":"<p><p>This study examines the integration of narrative medicine (NM) into primary healthcare (PHC) settings, evaluating its role in enhancing medical humanities education within grassroots healthcare institutions. Through a comprehensive literature review and case analysis, the research investigates the current state, challenges, and practical barriers to embedding NM into PHC systems, while proposing targeted strategies for improvement. The findings suggest that NM fosters stronger doctor-patient trust, enhances healthcare quality, and promotes humanistic care. However, primary hospitals face numerous challenges in advancing medical humanities, including a lack of trust between doctors and patients, tensions arising from the commercialization of healthcare, institutional limitations, unequal distribution of resources, and issues related to physicians' professional competencies and stress management. These interrelated obstacles detract from the quality of PHC services and the overall patient experience. Drawing on successful case studies from primary hospitals, the paper outlines effective strategies for overcoming these challenges. The study provides both theoretical and practical insights for advancing medical humanities in PHC, contributing to improvements in healthcare service quality and supporting the development of high standards in the healthcare sector. Ultimately, the findings aim to promote the broader adoption and ongoing refinement of NM within PHC institutions.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"105684"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant cutaneous ulcer in Epstein-Barr virus positive T-cell/NK-cell lymphoproliferative disorder: A case report.","authors":"Ya-Ping Guo, Zhi-Xin Wang, Shu-Li Guo","doi":"10.12998/wjcc.v13.i22.104258","DOIUrl":"10.12998/wjcc.v13.i22.104258","url":null,"abstract":"<p><strong>Background: </strong>Epstein-Barr virus (EBV)-positive T-cell/natural killer (NK)-cell lymphoproliferative disorder is a rare but challenging condition that requires multidisciplinary teamwork, including co-management by infection medicine, radiotherapy, rehabilitation, and psychology experts, as well as wound specialist nurses.</p><p><strong>Case summary: </strong>The patient was a 33-year-old female who presented with an erythema-like lesion on the left upper extremity that became desquamated and then blistered and eventually became a giant ulcer with exposed nerves and muscles. The left wrist had a fixed posture, and pathology tests showed cutaneous EBV-positive NK/T-cell proliferative disease. We employed a multidisciplinary collaborative treatment approach, and after 13 wound changes over 45 days, combined with radiation therapy, dietary supplementation, and psychosocial therapy, the left upper extremity wound healed.</p><p><strong>Conclusion: </strong>Giant ulcers caused by cutaneous EBV-positive NK/T-cell proliferative disease can be treated using a multidisciplinary collaborative approach.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"104258"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative pressure wound therapy with a fenestrated penrose drain for refractory seroma following ischial flap: A case report.","authors":"Sungyeon Kim, Hong Bae Jeon, Dong Hee Kang","doi":"10.12998/wjcc.v13.i22.107325","DOIUrl":"10.12998/wjcc.v13.i22.107325","url":null,"abstract":"<p><strong>Background: </strong>Patients with paraplegia are vulnerable to ischial pressure ulcers. Surgical treatments often lead to complications such as seroma and infection, necessitating repeated interventions that increase surgical difficulty. This case report aimed to introduce a novel treatment strategy combining negative pressure wound therapy (NPWT) with a fenestrated Penrose drain to manage refractory seroma in patients with a history of ischial pressure ulcers.</p><p><strong>Case summary: </strong>A 63-year-old woman presented with soft tissue defects on the left ischium and right trochanter. After surgical debridement, an inferior gluteal artery perforator (IGAP) flap was used to reconstruct the left ischium. NPWT was applied at a setting of 75 mmHg on postoperative day 3 owing to the development of seroma, combined with a fenestrated Penrose drain to facilitate effective drainage of serous fluid. A 54-year-old man presented with a 4 cm × 2 cm ulcer on the left ischium after previous excision and flap coverage. After thorough debridement, the IGAP flap was elevated, and NPWT with a fenestrated Penrose drain was implemented immediately postoperatively at 75 mmHg to promote drainage. Both patients achieved a stable recovery without complications.</p><p><strong>Conclusion: </strong>NPWT combined with a fenestrated Penrose drain placement is a promising strategy for addressing refractory seromas in cases of complex pressure ulcers.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"107325"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-SSA/Ro antibody-positive autoimmune myocarditis combined with complete atrioventricular block requiring implantation with a permanent pacemaker: A case report.","authors":"Peng-Bo Xiao, Xi-Rui Yang","doi":"10.12998/wjcc.v13.i22.104283","DOIUrl":"10.12998/wjcc.v13.i22.104283","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune myocarditis (AM) associated with autoimmune diseases can cause complete atrioventricular block (CAVB), but the related autoantigens and the underlying mechanisms are unclear. Anti-SSA/Ro antibodies may play an important role in this process, but cases of AM with positive anti-SSA/Ro antibodies are rare. In addition, arrhythmias, such as atrioventricular block, are very common in patients with autoimmune diseases, but severe atrioventricular block requiring permanent pacemaker implantation is extremely rare.</p><p><strong>Case summary: </strong>The patient in this case had AM with anti-SSA/Ro antibody positivity, which was associated with connective tissue disease, and the patient subsequently developed CAVB. After intensive immunosuppressive therapy, the antibody test results became negative, and pulmonary hypertension significantly improved. However, the outcome of permanent pacemaker implantation did not change.</p><p><strong>Conclusion: </strong>In clinical practice, the awareness of adult AM associated with autoimmune diseases combined with CAVB should be strengthened in clinicians, and anti-SSA/Ro antibodies may play a role in this process. Therefore, improving the detection of antibodies and early intervention, such as active immunosuppression therapy, may be very important for improving disease prognosis. For patients who do not respond to immunosuppressive therapy, implantation of a permanent pacemaker may become an essential treatment option.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"104283"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult ileo cecal intussusception as a manifestation of colon carcinoma: A case report.","authors":"Abdihakim Elmi Abdishakur, Mohamed Amiin Adan Ahmed","doi":"10.12998/wjcc.v13.i22.104352","DOIUrl":"10.12998/wjcc.v13.i22.104352","url":null,"abstract":"<p><strong>Background: </strong>Intussusception is the invagination of a segment of the bowel into an adjacent segment. It is the most common cause of intestinal obstruction in children, but in adults, it is rare, accounting for 1% of all intestinal obstructions and 5% of all intussusceptions, with malignancy being the most common cause. In the past, it was typically diagnosed intraoperatively. However, with the availability of computed tomography for abdominal imaging, recognizing the condition's signs has become crucial. Surgical intervention is essential for managing neoplastic cases and their complications.</p><p><strong>Case summary: </strong>A 45-year-old female presented with severe abdominal pain encompassing her entire abdomen, abdominal distension, vomiting, and persistent constipation. Over the past two months, she has also experienced considerable weight loss. After an initial history review, examination, and imaging investigations, the patient was diagnosed with ileo cecal intussusception resulting from a colo rectal mass located in the cecum and ascending colon. This condition was surgically managed through an extended right hemi colectomy.</p><p><strong>Conclusion: </strong>Intussusception is uncommon in adults, but it should be considered in patients with intestinal obstruction. Surgical intervention is essential.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"104352"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunoglobulin G4 biomarkers and pathogenesis in immunoglobulin G4-related spinal pachymeningitis.","authors":"Abdellatif Bouayad, Ahmed Amine El Oumri","doi":"10.12998/wjcc.v13.i22.105331","DOIUrl":"10.12998/wjcc.v13.i22.105331","url":null,"abstract":"<p><p>This letter to the editor highlights adding the diagnostic utility of immunoglobulin G4 (IgG4) measurements and its potential role in IgG4-related spinal pachymeningitis (IgG4-RSP) pathogenesis to the case reported by Chae TS <i>et al</i>, which focused on IgG4-RSP diagnosis based on magnetic resonance imaging findings and increased plasma IgG4 concentrations. A comprehensive understanding of both IgG4 serological and cerebrospinal fluid biomarkers is essential for managing this complex condition.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"105331"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of immature granulocyte and blood biomarkers in predicting perforated acute appendicitis using machine learning model.","authors":"Zeynep Kucukakcali, Sami Akbulut","doi":"10.12998/wjcc.v13.i22.104379","DOIUrl":"10.12998/wjcc.v13.i22.104379","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Acute appendicitis (AAp) is a prevalent medical condition characterized by inflammation of the appendix that frequently necessitates urgent surgical procedures. Approximately two-thirds of patients with AAp exhibit characteristic signs and symptoms; hence, negative AAp and complicated AAp are the primary concerns in research on AAp. In other terms, further investigations and algorithms are required for at least one third of patients to predict the clinical condition and distinguish them from uncomplicated patients with AAp.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To use a Stochastic Gradient Boosting (SGB)-based machine learning (ML) algorithm to tell the difference between AAp patients who are complicated and those who are not, and to find some important biomarkers for both types of AAp by using modeling to get variable importance values.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study analyzed an open access data set containing 140 people, including 41 healthy controls, 65 individuals with uncomplicated AAp, and 34 individuals with complicated AAp. We analyzed some demographic data (age, sex) of the patients and the following biochemical blood parameters: White blood cell (WBC) count, neutrophils, lymphocytes, monocytes, platelet count, neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, mean platelet volume, neutrophil-to-immature granulocyte ratio, ferritin, total bilirubin, immature granulocyte count, immature granulocyte percent, and neutrophil-to-immature granulocyte ratio. We tested the SGB model using n-fold cross-validation. It was implemented with an 80-20 training-test split. We used variable importance values to identify the variables that were most effective on the target.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The SGB model demonstrated excellent performance in distinguishing AAp from control patients with an accuracy of 96.3%, a micro aera under the curve (AUC) of 94.7%, a sensitivity of 94.7%, and a specificity of 100%. In distinguishing complicated AAp patients from uncomplicated ones, the model achieved an accuracy of 78.9%, a micro AUC of 79%, a sensitivity of 83.3%, and a specificity of 76.9%. The most useful biomarkers for confirming the AA diagnosis were WBC (100%), neutrophils (95.14%), and the lymphocyte-monocyte ratio (76.05%). On the other hand, the most useful biomarkers for accurate diagnosis of complicated AAp were total bilirubin (100%), WBC (96.90%), and the neutrophil-immature granulocytes ratio (64.05%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The SGB model achieved high accuracy rates in identifying AAp patients while it showed moderate performance in distinguishing complicated AAp patients from uncomplicated AAp patients. Although the model's accuracy in the classification of complicated AAp is moderate, the high variable importance obtained is clinically significant. We need further prospective validation studies, but the integration of such ML algorithms into clinical practice may improve diagnos","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"104379"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute pancreatitis after total aortic arch replacement leading to walled-off necrosis: A case report and review of literature.","authors":"Yuma Inoue, Yutaka Yata, Yuta Yokota, Zhao-Liang Li, Kazumi Kawabata","doi":"10.12998/wjcc.v13.i22.104165","DOIUrl":"10.12998/wjcc.v13.i22.104165","url":null,"abstract":"<p><strong>Background: </strong>Although acute pancreatitis and walled-off necrosis (WON) are rare complications following aortic surgery, they are serious risk factors for postoperative mortality. Considering the poor general condition of the postoperative patient, more effective and less invasive treatments are favorable.</p><p><strong>Case summary: </strong>A 67-year-old man was referred to our hospital for the treatment of WON after acute pancreatitis. He had undergone total aortic arch replacement due to aortic arch aneurysm and coronary artery bypass grafting due to angina pectoris 6 weeks prior in another hospital. On the second postoperative day, laboratory data and computed tomography showed that the patient had developed acute pancreatitis. Although conservative management (antibiotics, hydration, <i>etc.</i>) had helped in relieving the symptoms of acute pancreatitis, peripancreatic fluid collection (PFC) persisted, accompanied by duodenal obstruction and vomiting. Contrast-enhanced computed tomography showed that the heterogeneous enhancement and fluid collection in the pancreatic body and tail had increased, consistent with walled-off WON. We therefore performed endoscopic ultrasound-guided transluminal drainage for the PFC. As a result, the WON resolved gradually, resulting in improved oral intake.</p><p><strong>Conclusion: </strong>Acute pancreatitis is a rare gastrointestinal complication following thoracic and thoracoabdominal aortic aneurysm surgery. To the best of our knowledge, this is the first case of WON after aortic arch surgery treated with endoscopic ultrasound-guided transluminal drainage for PFC.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 22","pages":"104165"},"PeriodicalIF":1.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}