World Journal of Clinical Cases最新文献

{"title":"Navigating postoperative complications: Uveitis-glaucoma-hyphema syndrome after Ahmed glaucoma valve implantation.","authors":"Magdalena Ferrere, Ignacio Garcia-Mansilla, Agustina de Gainza","doi":"10.12998/wjcc.v12.i36.6944","DOIUrl":"10.12998/wjcc.v12.i36.6944","url":null,"abstract":"<p><p>Altwijri and Alsirhy reported a case of uveitis-glaucoma-hyphema syndrome after an Ahmed glaucoma valve implantation surgery in an advanced primary open-angle glaucoma patient, being the first ever recorded of its kind. The author describes the position of the tube as the origin of the anterior chamber inflammation and hyphema, which resolved shortly after shortening and relocating it. This publication emphasizes the importance of precise implant positioning and close-up patient follow-up after glaucoma filtration surgery as an important standard for healthcare providers.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6944-6946"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral blood pressure augmenting agents for intravenous vasopressor weaning.","authors":"John C Robinson, Mariam ElSaban, Nathan J Smischney, Patrick M Wieruszewski","doi":"10.12998/wjcc.v12.i36.6892","DOIUrl":"10.12998/wjcc.v12.i36.6892","url":null,"abstract":"<p><p>Intravenous (IV) vasopressors are essential in the management of hypotension and shock. Initiation of oral vasoactive agents to facilitate weaning of IV vasopressors to liberate patients from the intensive care unit is common despite conflicting evidence regarding the benefits of this practice. While midodrine appears to be the most frequently studied oral vasoactive agent for this purpose, its adverse effect profile may preclude its use in certain populations. In addition, some patients may require persistent use of IV vasopressors for hypotension refractory to midodrine. The use of additional and alternative oral vasoactive agents bearing different mechanisms of action is emerging. This article provides a comprehensive review of the pharmacology, clinical uses, dosing strategies, and safety considerations of oral vasoactive agents and their application in the intensive care setting.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6892-6904"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Chinese medicine treatment of insomnia based on microbial-gut-brain axis theory.","authors":"Xue-Jian Wang","doi":"10.12998/wjcc.v12.i36.6867","DOIUrl":"10.12998/wjcc.v12.i36.6867","url":null,"abstract":"<p><p>In recent years, insomnia has gradually become a common disease in society, which seriously affects people's quality of life. At present, with the deepening of research on intestinal microbiota-gut-brain axis in Western medicine, many studies suggest that regulating the gastrointestinal tract can treat brain-related diseases. It is found that brain-gut-bacteria axis plays an important role in the prevention and treatment of primary insomnia. At present, although the clinical treatment of insomnia with Western medicine can improve the insomnia symptoms of patients to a certain extent, there are still obvious adverse reactions, such as anxiety and depression, drug addiction, <i>etc.</i>, so long-term oral drug therapy cannot be carried out. Traditional Chinese medicine (TCM) and acupuncture techniques have certain therapeutic effects on insomnia. TCM believes that the brain and gastrointestinal system are connected through the meridian, and the pathophysiology is closely related. This paper will discuss the theory and feasibility of TCM for the treatment of insomnia from the pathological relationship between brain-gut axis, intestinal flora and insomnia.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6867-6870"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential of traditional Chinese medicine lyophilized powder of <i>Poecilobdella manillensis</i> in the treatment of hyperuricemia.","authors":"Kang-Ming Huang, Hong-Bin Chen, Jin-Rong Lin","doi":"10.12998/wjcc.v12.i36.6939","DOIUrl":"10.12998/wjcc.v12.i36.6939","url":null,"abstract":"<p><p>Traditional Chinese medicine has a long and illustrious history, and with the development of modern science and technology, the research and application of traditional Chinese medicines have continued to progress significantly. Many traditional Chinese medicinal herbs have undergone scientific validation, reinvigorating with new life and vitality, and contributing unique strengths to the advancement of human health. Recently, the discovery that leech total protein extracted from <i>Poecilobdella manillensis</i> lyophilized powder reduces blood uric acid (UA) levels by inhibiting the activity of xanthine oxidase to decrease UA synthesis and promotes UA excretion by regulating different UA transporters in the kidney and intestine has undoubtedly injected new vitality and hope into this field of research. The purpose of this editorial is to comment on this study, explore its strengths and weaknesses, and there is a hope to treat a range of metabolic-related syndromes, including hyperuricemia, by targeting the gut microbiota.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6939-6943"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MiRNA-200a and miRNA-200b expression, and vitamin-D level: Prognostic significance in obese non-diabetic and obese type 2 diabetes mellitus individuals.","authors":"Abrar Fahad Alshahrani, Fauzia Ashfaq, Abdulrahman A Alsayegh, Mohammed Bajahzer, Mohammad Idreesh Khan, Mirza Masroor Ali Beg","doi":"10.12998/wjcc.v12.i36.6916","DOIUrl":"10.12998/wjcc.v12.i36.6916","url":null,"abstract":"<p><strong>Background: </strong>Obesity and type 2 diabetes mellitus (T2DM) are frequent co-occurring disorders that affect regular metabolic functions. Obesity has also been linked to an increased risk of developing diabetes. Obesity and diabetes are on the rise, increasing healthcare costs and raising mortality rates. Research has revealed that the expression profile of microRNAs (miRNAs) changes as diabetes progresses. Furthermore, vitamin D may have an anti-obesity effect and inverse association with body weight and body mass index (BMI). Low vitamin D levels do not solely cause obesity, which could be a factor in the etiology of T2DM.</p><p><strong>Aim: </strong>To evaluate miRNA-200a and miRNA-200b expression, and vitamin-D levels in obese and obese T2DM individuals.</p><p><strong>Methods: </strong>This study included 210 participants, of which, 82 were obese (BMI > 30 kg/m²) without T2DM, 28 were obese with T2DM, and 100 were healthy controls. BMI was evaluated and both fasting and postprandial blood glucose were used to confirm T2DM. Exosomal miRNA-200a and miRNA-200b expression were analyzed using real-time PCR using Taqman probes, and vitamin-D levels were evaluated using an electrochemiluminescence-based immunoassay technique. All data analyses were performed using SPSS 20.0 and GraphPad Prism 5 software.</p><p><strong>Results: </strong>Overall, a 2.20- and 4.40-fold increase in miRNA-200a and miRNA-200b expression was observed among participants compared to healthy controls. MiRNA-200a and miRNA-200b expression among obese participants increased 2.40-fold and 3.93-fold, respectively, while in obese T2DM participants these values were 2.67-fold, and 5.78-fold, respectively, and these differences were found to be statistically significant (<i>P</i> = 0.02) (<i>P</i> < 0.0001). Obese participants showed a vitamin D level of 34.27 ng/mL, while in obese-T2DM participants vitamin D level was 22.21 ng/mL (<i>P</i> < 0.0001). Vitamin D was negatively correlated with miRNA-200a (<i>r</i> = -0.22, <i>P</i> = 0.01) and miRNA-200b (<i>r</i> = -0.19, <i>P</i> = 0.04). MiRNA-200a sensitivity was 75%, and specificity was 57%, with a cutoff value of 2.07-fold. MiRNA-200b sensitivity was 75%, and specificity was 71% with a cutoff value of 4.12-fold, suggesting that miRNA-200a and miRNA-200b with an increased expression of 2.07- and 4.12-fold could be predictive indicators for the risk of diabetes in obese participants.</p><p><strong>Conclusion: </strong>MiRNA-200a and miRNA-200b were higher in diabetic obese participants <i>vs</i> non-diabetic obese participants, and insufficient vitamin D levels in obese T2DM participants may be involved in poor clinical outcome.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6916-6925"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of posterior approach for resection of spinal meningioma: Impact of dural attachment location.","authors":"Hong Chen, Ya-Ni Fu, Chu-Di Fu","doi":"10.12998/wjcc.v12.i36.6905","DOIUrl":"10.12998/wjcc.v12.i36.6905","url":null,"abstract":"<p><strong>Background: </strong>Spinal meningiomas (SMs) are common benign tumors that are typically treated with surgical resection. The choice of surgical approach may vary depending on the location of dural attachment of the SM, with a posterior approach being the traditional preference. However, there is limited research available on the impact of dural attachment location on outcomes following posterior approach for SM resection.</p><p><strong>Aim: </strong>To investigate the outcomes of posterior approach for SM resection, and compare the results among different dural attachment location subgroups.</p><p><strong>Methods: </strong>Between January 2013 and February 2023, a total of 34 SM patients were included in the study. Various clinical and radiologic features, functional states before and after surgery, operating time, intraoperative blood loss, tumor recurrence, and perioperative complications were assessed and compared.</p><p><strong>Results: </strong>The average age of the included 34 patients' (10 males and 24 females) age was 62.09 years. Mean follow-up duration was 22.65 months. The location of SM was the thoracic spine in 32 cases, with only 2 in the cervical spine. On average, intraoperative blood loss was 520.59 mL, and operating time was 176.76 minutes. Thirty three cases had successful outcomes while only 1 experienced an unexpected outcome. The tumor recurrence rate was 2.9%. After surgery, there were 3 cases of cerebral spinal fluid leakage, 1 case of pneumonia, and 1 case of urinary tract infection. Dural attachments were predominantly found dorsal or dorsolateral (13 cases), followed by ventral or ventrolateral (14 cases), and lateral (7 cases). The outcomes among these subgroups were similar.</p><p><strong>Conclusion: </strong>The posterior approach for SM resection is safe and effective, yielding comparable surgical and neurological outcomes regardless of the dural attachment location.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6905-6915"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing cardiovascular outcomes with dapagliflozin and sacubitril in post-acute myocardial infarction heart failure and type 2 diabetes mellitus.","authors":"Dong-Hua Liu, Xiao-Ming Dong, Wen-Jie Long","doi":"10.12998/wjcc.v12.i36.6935","DOIUrl":"10.12998/wjcc.v12.i36.6935","url":null,"abstract":"<p><p>Coronary heart disease and type 2 diabetes mellitus (T2DM) often co-occur, presenting substantial health risks, particularly following acute myocardial infarction (AMI). While percutaneous coronary intervention (PCI) is a prevalent treatment, complications such as microvascular dysfunction may lead to heart failure, necessitating additional therapies. This editorial examines the emerging roles of sacubitril/valsartan and sodium-glucose co-transporter 2 inhibitors in managing post-PCI. Recent research investigates the combined effects of dapagliflozin and telmisartan on myocardial microperfusion in post-AMI heart failure patients with T2DM. The findings suggest that this combination enhances myocardial microcirculation, improves cardiac function, and achieves better glycemic control, with a reduced incidence of major adverse cardiovascular events. Despite ongoing challenges, the integration of dapagliflozin and sacubitril/valsartan represents a significant advancement in post-AMI care. Further investigation in larger cohorts and more diverse patient populations is required to confirm its long-term clinical outcomes.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6935-6938"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic intractable nontuberculous mycobacterial-infected wound after acupuncture therapy in the elbow joint: A case report.","authors":"Jong Hyup Kim, In Chang Koh, Soo Yeon Lim, Seong Hee Kang, Hoon Kim","doi":"10.12998/wjcc.v12.i36.6926","DOIUrl":"10.12998/wjcc.v12.i36.6926","url":null,"abstract":"<p><strong>Background: </strong>Musculoskeletal <i>nontuberculous Mycobacterium</i> (NTM) infections are rare, particularly post-acupuncture therapy, and present diagnostic challenges due to their infrequency and potential severity. Prompt recognition and appropriate management are crucial for optimal outcomes. NTM-infected wounds involving the joints are difficult to treat, and only a few cases have been reported.</p><p><strong>Case summary: </strong>We present a case of a chronic intractable NTM-infected wound on the elbow joint that completely healed with conservative wound care and antibiotic treatment. An 81-year-old woman presented with a chronic, ulcerative wound on the right elbow joint where she had undergone repeated acupuncture therapy for chronic intolerable pain. Magnetic resonance imaging revealed synovial thickening, effusion, and subcutaneous cystic lesions. An orthopedic surgeon performed open synovectomy and serial debridement. However, 1 month postoperatively, the wound had not healed and became chronic. A wound culture revealed NTM (<i>Mycobacterium abscessus</i>), and the patient was referred to the Department of Plastic and Reconstructive Surgery. Instead of surgical intervention, conservative wound care with intravenous antibiotics was provided, considering the wound status and the patient's poor general condition. Complete wound healing was achieved in 12 months, with no impact on the range of motion of the elbow joint.</p><p><strong>Conclusion: </strong>With clinical awareness, musculoskeletal NTM infection can be treated with conservative wound care and appropriate antimicrobial agents.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6926-6934"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary organizing pneumonia after infection.","authors":"Lertluksana Limkul, Prakarn Tovichien","doi":"10.12998/wjcc.v12.i36.6877","DOIUrl":"10.12998/wjcc.v12.i36.6877","url":null,"abstract":"<p><p>This editorial explores the clinical implications of organizing pneumonia (OP) secondary to pulmonary tuberculosis, as presented in a recent case report. OP is a rare condition characterized by inflammation in the alveoli, which spreads to alveolar ducts and terminal bronchioles, usually after lung injuries caused by infections or other factors. OP is classified into cryptogenic (idiopathic) and secondary forms, the latter arising after infections, connective tissue diseases, tumors, or treatments like drugs and radiotherapy. Secondary OP may be triggered by infections caused by bacteria, viruses, fungi, mycobacteria, or parasites. Key diagnostic features include subacute onset of nonspecific respiratory symptoms such as dry cough, chest pain, and exertional dyspnea. Imaging with computed tomography scans typically reveals three patterns: (1) Bilateral subpleural consolidation; (2) Nodular consolidation; and (3) A reticular pattern. Bronchoscopy with bronchoalveolar lavage helps exclude other causes. Standard treatment consists of corticosteroid therapy tapered over 6 months to 12 months. This editorial highlights clinical and diagnostic strategies to ensure timely and effective patient care.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6877-6882"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Merits and demerits of administering esketamine in preventing postpartum depression following cesarean section.","authors":"Takahiko Nagamine","doi":"10.12998/wjcc.v12.i36.6883","DOIUrl":"10.12998/wjcc.v12.i36.6883","url":null,"abstract":"<p><p>Emergency cesarean section is associated with the development of postpartum depression. Esketamine has been demonstrated to have a rapid onset of antidepressant effects. Randomized controlled trials and meta-analyses have demonstrated the efficacy of esketamine in preventing postpartum depression after cessarean section. However, the data included in these analyses were derived from elective cesarean sections and differed in the dose and timing of esketamine administration. Esketamine is a dissociative anesthetic with a dose-dependent risk of inducing psychotic symptoms, including hallucinations. In the setting of cesarean section, esketamine should be administered with caution and only if the potential benefits outweigh the risks.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 36","pages":"6883-6886"},"PeriodicalIF":1.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}