免疫球蛋白G4相关脊髓性厚性脑膜炎的生物标志物和发病机制。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

World Journal of Clinical Cases Pub Date : 2025-08-06 DOI:10.12998/wjcc.v13.i22.105331

Abdellatif Bouayad, Ahmed Amine El Oumri

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引用次数: 0

摘要

这封致编辑的信强调了将免疫球蛋白G4 （IgG4）测量的诊断实用性及其在IgG4相关的脊髓性肿脑膜炎（IgG4- rsp）发病机制中的潜在作用添加到Chae TS等人报告的病例中，该病例的重点是基于磁共振成像结果和血浆IgG4浓度升高的IgG4- rsp诊断。全面了解IgG4血清学和脑脊液生物标志物对于治疗这种复杂的疾病至关重要。

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Immunoglobulin G4 biomarkers and pathogenesis in immunoglobulin G4-related spinal pachymeningitis.

This letter to the editor highlights adding the diagnostic utility of immunoglobulin G4 (IgG4) measurements and its potential role in IgG4-related spinal pachymeningitis (IgG4-RSP) pathogenesis to the case reported by Chae TS et al, which focused on IgG4-RSP diagnosis based on magnetic resonance imaging findings and increased plasma IgG4 concentrations. A comprehensive understanding of both IgG4 serological and cerebrospinal fluid biomarkers is essential for managing this complex condition.

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

自引率

0.00%

发文量

3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.