Late menstruation with an ovarian sclerosing stromal tumor: A case report.

Background: Ovarian sclerosing stromal tumors (OSSTs) are found most commonly in females at 20-30 years of age. They can also occur at any point during pre-puberty, puberty, or menopause. Clinical manifestations of OSSTs include abdominal pain, an abdominal mass, menstrual abnormalities, and infertility. Infrequently, patients will experience androgen-related manifestations of masculinization, such as increased hair, acne, or a low voice. Diagnosis must be confirmed by immunohistochemical analysis of the tissue as clinical symptoms and imaging studies are unreliable.

CASE SUMMARYA 14-year-old female presented with amenorrhea. After a thorough medical examination, endocrine and tumor markers analysis, and imaging, a pelvic mass was discovered. The patient also exhibited endocrine dysfunction but was not positive for any tumor markers. The patient underwent surgery to remove the ovarian tumor. Immunohistochemical analysis of the resected specimen indicated an OSST. During the postoperative follow-up, the patient had attained menarche.

CONCLUSIONThis case's clinical manifestation of endocrine dysfunction due to OSST provides new insights that will assist clinicians in the diagnosis and treatment of this common tumor.