Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre
{"title":"Cutaneous nocardiosis in chronic renal insufficiency: Diagnostic and therapeutic considerations.","authors":"Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre","doi":"10.12998/wjcc.v13.i26.108211","DOIUrl":"10.12998/wjcc.v13.i26.108211","url":null,"abstract":"<p><p>Nocardiosis remains a rare and often underdiagnosed bacterial infection, particularly in immunocompromised individuals. The case report by Zhang <i>et al</i> highlights the diagnostic and therapeutic challenges in managing <i>Nocardia brasiliensis</i> skin infection in a 93-year-old patient with chronic renal insufficiency. This editorial explores the importance of timely diagnosis, microbiological confirmation, and tailored antibiotic therapy. Emphasis is placed on the role of immune status evaluation, drug concentration monitoring, and the necessity of long-term antimicrobial therapy. Improved clinician awareness and adherence to evidence-based management protocols are essential to achieving better outcomes in nocardiosis cases.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"108211"},"PeriodicalIF":1.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastrointestinal metastasis from invasive lobular carcinoma following breast cancer treatment: A case report.","authors":"Ping-Ping Liu, Ling-Ling Sun, Xue Jing","doi":"10.12998/wjcc.v13.i26.107496","DOIUrl":"10.12998/wjcc.v13.i26.107496","url":null,"abstract":"<p><strong>Background: </strong>Metastasis of breast cancer usually affects the lungs, bones, liver, and brain. It rarely spreads to the gastrointestinal tract, and cases with similar endoscopic manifestations are even rarer. Herein, we report a 52-year-old woman presenting with metastatic lobular carcinoma involving the gastrointestinal tract four years following a left mastectomy, chemoradiotherapy, and hormone therapy for lobular carcinoma of the breast.</p><p><strong>Case summary: </strong>A 52-year-old woman presented with a history of invasive lobular carcinoma and experienced metastasis of breast cancer to the gastrointestinal tract. The patient underwent a left mastectomy and tumor cells were positive for estrogen receptor (ER) and progesterone receptor (PR), negative for human epidermal growth factor receptor 2 (HER2) and E-cadherin. She did not experience any local or distant recurrences for four years following the mastectomy, chemoradiotherapy, and hormone therapy. However, the patient complained of upper abdominal discomfort and was transferred to our hospital. The endoscopic examination revealed multiple crater-like ulcers scattered throughout the stomach, gastric antrum, and colorectum. Surprisingly, the histology of colorectum lesions was the same as that of gastric metastasis. Gastric tumor cells were positive for GATA-binding protein 3 (GATA3), PR, and ER, negative for HER2. The colorectum tumor cells were positive for GATA3 and ER and negative for cytokeratin 20. Based on the results of immunohistological examination, a final diagnosis of gastrointestinal metastases from breast cancer was established.</p><p><strong>Conclusion: </strong>Distinguishing metastatic breast cancer from primary gastrointestinal lesions is crucial for initiating the correct treatment and enhancing the quality of life for patients.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"107496"},"PeriodicalIF":1.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adenoid cystic carcinoma of the Bartholin's gland: Two case reports and review of literature.","authors":"Ping Liu, Hui-Qiong Huang, Ce Bian, Yi Quan","doi":"10.12998/wjcc.v13.i26.108052","DOIUrl":"10.12998/wjcc.v13.i26.108052","url":null,"abstract":"<p><strong>Background: </strong>Adenoid cystic carcinoma (ACC) of the Bartholin's gland represents an exceptionally rare malignancy with limited documented cases in the medical literature. It typically manifests as a solid mass that clinically warrants suspicion for neoplastic processes.</p><p><strong>Case summary: </strong>This case series details two cases of primary ACC cases involving the Bartholin's gland treated with radical surgical resection of the vaginal lesions. Notably, divergent therapeutic approaches resulted in contrasting prognoses: The patient receiving adjuvant radiotherapy following surgery maintained disease-free status with no locoregional recurrence or metastatic progression through 58 months of surveillance. Conversely, the non-radiated patient experienced disease recurrence within 18 months postoperatively.</p><p><strong>Conclusion: </strong>Our findings suggest that postoperative radiation therapy may significantly decrease local recurrence rates in Bartholin's gland ACC, potentially influencing long-term disease control. This comparative outcome analysis underscores the importance of integrating adjuvant radiotherapy integration into treatment protocols for this rare malignancy.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"108052"},"PeriodicalIF":1.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hye-Won Jeong, Ji-Won Jung, Sang-Hyuk Jang, Dong-Yoon Kim, Ji-Young Lee, Jong-Sik Jang
{"title":"Effects of driving simulator intervention on post-traumatic stress disorder symptoms after traffic accidents: A single-subject study.","authors":"Hye-Won Jeong, Ji-Won Jung, Sang-Hyuk Jang, Dong-Yoon Kim, Ji-Young Lee, Jong-Sik Jang","doi":"10.12998/wjcc.v13.i26.100363","DOIUrl":"10.12998/wjcc.v13.i26.100363","url":null,"abstract":"<p><strong>Background: </strong>Although exposure therapy is a proven treatment for post-traumatic stress disorder (PTSD), empirical research is difficult due to ethical issues. Recently, virtual reality-based content that can provide space and time similar to reality for exposure therapy techniques is increasing.</p><p><strong>Aim: </strong>To examine exposure therapy using driving simulations in patients with PTSD due to traffic accidents with PTSD symptoms.</p><p><strong>Methods: </strong>The intervention was provided to two individuals who experienced PTSD symptoms after a traffic accident using a driving simulator. Among the single-subject experimental designs, the ABA (baseline-intervention-baseline) design was used, and the PTSD checklist and brain wave frequency were used to measure the results.</p><p><strong>Results: </strong>In all participants, the standard category departure time of the electroencephalogram decreased from baseline, and PTSD symptoms decreased after the intervention.</p><p><strong>Conclusion: </strong>These results suggest the potential use of a driving simulator as an exposure treatment tool for PTSD.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"100363"},"PeriodicalIF":1.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arnold Méndez-Toro, Felipe Alejandro Muñoz-Rossi, Rafael Enrique Tejada-Cabrera, Ingrid Tatiana Rojas-Ruiz, Juan David Flechas-Ardila, Alejandro García-Gutiérrez, Ricardo Andrés Novoa-Álvarez
{"title":"Monitoring high-risk patients for chemotherapy-related cardiotoxicity: A retrospective analysis.","authors":"Arnold Méndez-Toro, Felipe Alejandro Muñoz-Rossi, Rafael Enrique Tejada-Cabrera, Ingrid Tatiana Rojas-Ruiz, Juan David Flechas-Ardila, Alejandro García-Gutiérrez, Ricardo Andrés Novoa-Álvarez","doi":"10.12998/wjcc.v13.i26.107716","DOIUrl":"10.12998/wjcc.v13.i26.107716","url":null,"abstract":"<p><strong>Background: </strong>Cancer incidence remains a global challenge. The World Health Organization reported 19976499 new cases in 2022, including 1551060 in Latin America and the Caribbean. While chemotherapy advances have improved survival, these treatments carry significant risks, particularly cardiovascular complications impacting morbidity and mortality. Early cardiotoxicity detection enables targeted interventions, guiding clinical decisions on treatment adjustments to mitigate damage and preserve function. Cardiac imaging and biomarkers assess cardiotoxicity before, during, and after therapy. Despite their importance, the lack of a structured multidisciplinary program hinders early detection and management in high-risk patients.</p><p><strong>Aim: </strong>To evaluate the use of diagnostic tools for monitoring cardiotoxicity in cancer patients receiving high-risk chemotherapy at the National University Hospital of Colombia.</p><p><strong>Methods: </strong>This observational, retrospective cohort study included patients aged ≥ 18 with cancer treated with potentially cardiotoxic chemotherapy at the National University Hospital of Colombia (2016-2019). Data from medical records included demographics, comorbidities, biomarkers, and echocardiographic parameters. Cardiotoxicity was defined by reduced left ventricular ejection fraction (LVEF) using Simpson's method and biomarker abnormalities. Statistical analysis included descriptive methods to compare pre- and post-chemotherapy use of biomarkers and echocardiographic parameters.</p><p><strong>Results: </strong>From a total of 195 patients analyzed, 8.7% (<i>n</i> = 17) developed cardiotoxicity, predominantly mild (58.8%, <i>n</i> = 10). Affected patients were mostly male (64.7%, <i>n</i> = 11) with a mean age of 51.88 ± 15.9 years. The median LVEF declined from 62% [interquartile range (IQR): 58%-66%] at baseline to 46% (IQR: 34%-56%) post-treatment. STRAIN longitudinal values also significantly decreased, from -18.38 ± 4.62% at baseline to -14.22 ± 4.93% post-treatment. Troponin was measured in 58.8% (<i>n</i> = 10) of cardiotoxicity cases, while ProBNP was less frequently used (17.6%, <i>n</i> = 3).</p><p><strong>Conclusion: </strong>This study highlights the utility of echocardiography and biomarkers in assessing cardiotoxicity in oncology patients, emphasizing the need for standardized protocols to optimize early diagnosis and management. However, the retrospective nature of the study and the insufficient use of biomarkers may limit the generalizability of the findings.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"107716"},"PeriodicalIF":1.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ocular siderosis secondary to occult intraocular foreign body causing secondary glaucoma: A case report.","authors":"Ling-Xiao Xu, Yi-Chun Kong","doi":"10.12998/wjcc.v13.i25.104134","DOIUrl":"10.12998/wjcc.v13.i25.104134","url":null,"abstract":"<p><strong>Background: </strong>Occult intraocular foreign bodies (IOFBs) can present with atypical symptoms and clinical signs, making diagnosis challenging. We describe a case of an undetected IOFB that was missed on both computed tomography and B-ultrasound, ultimately leading to ocular siderosis and secondary glaucoma.</p><p><strong>Case summary: </strong>A 55-year-old male patient presented to our clinic reporting a one-month history of right ocular discomfort and progressive visual deterioration. The patient had previously received a glaucoma diagnosis at a local healthcare facility. His ocular history included blunt trauma to the affected eye five years prior to presentation. Slit-lamp examination revealed corneal and iris lesions in the right eye. Pupillary dilation facilitated the identification of traumatic lens opacities. Diagnostic imaging modalities, including B-scan ultrasonography and computed tomography, showed no evidence of retained intraocular foreign material. The patient subsequently underwent uncomplicated pars plana vitrectomy, during which the occult foreign body was successfully extracted. The procedure was completed without intraoperative or immediate postoperative complications.</p><p><strong>Conclusion: </strong>Awareness of IOFBs in individuals who work in high-risk occupations and prompt referral to a retinal surgeon are very important.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 25","pages":"104134"},"PeriodicalIF":1.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyungsun Jun, Myungseok Ryu, Hyocheong Chae, Hongmin Chu, Kwangho Kim, Do-Eun Lee, Hanbit Jin, Sungjun Joo, Dasol Park, Jungtae Leem, Hyung Won Kang
{"title":"Response to Korean medicine with acupotomy in patients with cognitive impairment in primary care: A multicenter registry protocol.","authors":"Hyungsun Jun, Myungseok Ryu, Hyocheong Chae, Hongmin Chu, Kwangho Kim, Do-Eun Lee, Hanbit Jin, Sungjun Joo, Dasol Park, Jungtae Leem, Hyung Won Kang","doi":"10.12998/wjcc.v13.i25.107484","DOIUrl":"10.12998/wjcc.v13.i25.107484","url":null,"abstract":"<p><strong>Background: </strong>Mild cognitive impairment (MCI) and subjective cognitive decline (SCD) are risk indicators for dementia and require ongoing management. Traditional Korean medicine (TKM) commonly employs acupuncture and herbal medicine for cognitive impairment; yet, clinical research on acupotomy is lacking. Although most TKM treatments occur in primary care, the research is largely hospital-based. This registry was established to systematically collect real-world data on the clinical progress, efficacy, and safety of TKM with acupotomy for patients with MCI or SCD in primary care. It is hypothesized that TKM with acupotomy improves cognitive function and is safe for these patients.</p><p><strong>Aim: </strong>To establish an MCI or SCD registry of patients receiving TKM, including acupotomy, to analyze its clinical efficacy and safety.</p><p><strong>Methods: </strong>This observational registry study will be conducted across 22 medical institutions; approximately 500 participants will be recruited. Data-sociodemographic information, medication history, height, weight, vital signs, and assessment questionnaires (Montreal Cognitive Assessment-Korean, short form of Korean-Everyday Cognition, Numeric Rating Scale, Korean version of the Insomnia Severity Index)-will be collected at 3-month intervals over a year. This study will also document the TKM treatment administered and any adverse events. Routine TKM procedures will be followed, with acupuncture and acupotomy administered as per protocol; treatments including herbal medicine, Chuna therapy, and moxibustion may be administered at the practitioner's discretion.</p><p><strong>Results: </strong>The registry will capture a wide range of real-world clinical data regarding demographic profiles, treatment processes, and adverse events. This detailed documentation is expected to clarify patient characteristics, evaluate the clinical course, and identify factors that may affect cognitive improvement in patients with MCI and SCD.</p><p><strong>Conclusion: </strong>This research may provide evidence supporting acupotomy for cognitive impairment in primary care by confirming its efficacy and safety, providing preliminary evidence for TKM-based interventions aimed at improving cognitive function.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 25","pages":"107484"},"PeriodicalIF":1.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chih-Wei Hsu, Chuen Hsueh, Yu-Ling Lu, Chia-Jung Hsu, Richard J Wong, Shu-Fu Lin
{"title":"Risk factors and outcomes of metastatic poorly differentiated thyroid carcinoma.","authors":"Chih-Wei Hsu, Chuen Hsueh, Yu-Ling Lu, Chia-Jung Hsu, Richard J Wong, Shu-Fu Lin","doi":"10.12998/wjcc.v13.i25.105204","DOIUrl":"10.12998/wjcc.v13.i25.105204","url":null,"abstract":"<p><strong>Background: </strong>Poorly differentiated thyroid carcinoma (PDTC) is a rare and aggressive form of thyroid cancer. Distant metastasis occurs frequently in PDTC.</p><p><strong>Aim: </strong>To determine factors associated with distant metastasis and the effects of metastasis, either diagnosed on initial presentation or developing during follow-up, on mortality in PDTC patients.</p><p><strong>Methods: </strong>Patients with PDTC diagnosed between January 1, 1985 and July 31, 2022 were identified using a thyroid cancer database at a medical center in Taiwan. Factors associated with distant metastasis and cancer-specific survival (CSS) were analyzed using binary logistic analysis and Cox regression, respectively. Survival analysis was conducted using the Kaplan-Meier method.</p><p><strong>Results: </strong>The study cohort included 39 patients with PDTC, including 16 with distant metastasis on initial presentation, 5 with metastasis during the follow-up period, and 18 with no evidence of metastasis. Older age (≥ 45 years) was significantly associated with a higher risk of distant metastasis (odds ratio: 5.31; 95% confidence interval: 1.27-22.2; <i>P</i> = 0.018), while sex, tumor size, T stage, and N stage were not associated with distant metastasis. Patients with metastatic PDTC, either diagnosed at presentation or developing during follow-up, had poorer 5-year CSS rates (55.0% and 40.0%, respectively) than those without metastasis (5-year CSS, 93.8%) (<i>P</i> = 0.001 for both comparisons).</p><p><strong>Conclusion: </strong>Older patients with PDTC have an increased risk of distant metastasis. Patients with metastatic PDTC, both diagnosed at presentation and developing during follow-up, have a dismal prognosis.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 25","pages":"105204"},"PeriodicalIF":1.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Different clinical profile of leptospirosis in a tertiary care Indian hospital: A Himalayan experience.","authors":"Drupad Das, Sindura Ponnampurathu, Prasan Kumar Panda, Yogendra Pratap Mathuria","doi":"10.12998/wjcc.v13.i25.106335","DOIUrl":"10.12998/wjcc.v13.i25.106335","url":null,"abstract":"<p><strong>Background: </strong>Leptospirosis is a globally prevalent zoonotic disease with a significant burden in tropical and subtropical regions, including India. Despite its high fatality rate and endemic nature, the disease remains underreported in many areas, particularly in Northern India.</p><p><strong>Aim: </strong>To analyze the demography, clinical presentation, complications, and mortality risk factors in presumptive leptospirosis patients admitted to a tertiary care hospital over the last 7 years from the Himalayan and Sub-Himalayan regions of Northern India.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on hospital records of patients admitted with leptospirosis at the All India Institute of Medical Sciences, Rishikesh, between January 2018 and December 2024. Diagnosis was based on the Modified Faine's Criteria and laboratory confirmation <i>via</i> IgM enzyme-linked immunosorbent assay (ELISA) and other diagnostic tests. Statistical analysis, including logistic regression, was performed to determine mortality predictors.</p><p><strong>Results: </strong>A total of 62 patients were included in the study. The most common symptoms were fever (98.39%), myalgia (41.94%), and jaundice (20.97%). Thrombocytopenia was the most frequent complication, occurring in 72.58% of cases, followed by hepatic involvement (62.9%) and acute kidney injury (40.32%). Multiorgan dysfunction syndrome was present in 66.13% of cases, with 19.35% developing acute respiratory distress syndrome (ARDS). The overall mortality rate was 20.97%, with a higher but non-significant mortality trend in the Himalayan region (35% <i>vs</i> 14.29%, <i>P</i> = 0.094). Logistic regression analysis revealed that no categorical predictor alone was statistically significant. However, ARDS had a high odds ratio (OR = 2.10), suggesting clinical importance despite variability. Jaundice (OR = 2.28, <i>P</i> = 0.383) and creatinine levels (OR = 2.12, <i>P</i> = 0.1029) showed a possible trend toward increased mortality, despite statistical variability. Higher international normalized ratio levels (OR = 0.33, <i>P</i> = 0.0662) were suggestive of a protective effect.</p><p><strong>Conclusion: </strong>Leptospirosis remains a severe and often fatal disease in Himalayan and sub-Himalayan regions, particularly in hilly areas, where underreporting and delayed diagnosis contribute to poor outcomes. Mortality was highest (33.33%) in cases with multiorgan involvement, particularly affecting the liver, kidneys, and lungs. We did not identify any statistically significant mortality predictors. Although the study did not assess the impact of timely diagnosis, improving healthcare accessibility in hilly regions may facilitate earlier detection and intervention, potentially reducing mortality.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 25","pages":"106335"},"PeriodicalIF":1.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nursing care of a patient with negative symptoms of schizophrenia who underwent tracheotomy: A case report.","authors":"Jin-Yuan Li, Xiao-En Liu, Wei Li, Li-Na Wang","doi":"10.12998/wjcc.v13.i25.108124","DOIUrl":"10.12998/wjcc.v13.i25.108124","url":null,"abstract":"<p><strong>Background: </strong>Patients with schizophrenia may lack awareness of the importance of post-tracheotomy care due to the impact of their condition, often showing resistance or misunderstanding of care measures. When coupled with the impact of negative symptoms and the risk of complications after tracheotomy, patients may experience emotional fluctuations, restlessness, anxiety, and hostile behaviors, which pose significant challenges to nursing work.</p><p><strong>Case summary: </strong>We have reported the case of an 87-year-old male patient who was admitted to the hospital because of negative symptoms of schizophrenia and who underwent tracheotomy for severe pneumonia. In this study, we have summarized the nursing experience of a patient with negative symptoms of schizophrenia who underwent tracheotomy. The key nursing strategies included proper tracheotomy care, the management of psychiatric symptoms, a thorough assessment and implementation of enteral and parenteral nutrition, effective skincare, infection prevention, and comprehensive mental care. Individualized nursing skills helped stabilize the patient's condition, followed by isolation and observation in a psychiatric hospital.</p><p><strong>Conclusion: </strong>Effective postoperative tracheostomy care in patients with schizophrenia necessitates a tailored, multidisciplinary approach that addresses their psychiatric, physical, and emotional needs to achieve optimal clinical outcomes.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 25","pages":"108124"},"PeriodicalIF":1.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}