Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre
{"title":"慢性肾功能不全的皮肤诺卡病:诊断和治疗的考虑。","authors":"Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre","doi":"10.12998/wjcc.v13.i26.108211","DOIUrl":null,"url":null,"abstract":"<p><p>Nocardiosis remains a rare and often underdiagnosed bacterial infection, particularly in immunocompromised individuals. The case report by Zhang <i>et al</i> highlights the diagnostic and therapeutic challenges in managing <i>Nocardia brasiliensis</i> skin infection in a 93-year-old patient with chronic renal insufficiency. This editorial explores the importance of timely diagnosis, microbiological confirmation, and tailored antibiotic therapy. Emphasis is placed on the role of immune status evaluation, drug concentration monitoring, and the necessity of long-term antimicrobial therapy. Improved clinician awareness and adherence to evidence-based management protocols are essential to achieving better outcomes in nocardiosis cases.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"13 26","pages":"108211"},"PeriodicalIF":1.0000,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336841/pdf/","citationCount":"0","resultStr":"{\"title\":\"Cutaneous nocardiosis in chronic renal insufficiency: Diagnostic and therapeutic considerations.\",\"authors\":\"Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre\",\"doi\":\"10.12998/wjcc.v13.i26.108211\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Nocardiosis remains a rare and often underdiagnosed bacterial infection, particularly in immunocompromised individuals. The case report by Zhang <i>et al</i> highlights the diagnostic and therapeutic challenges in managing <i>Nocardia brasiliensis</i> skin infection in a 93-year-old patient with chronic renal insufficiency. This editorial explores the importance of timely diagnosis, microbiological confirmation, and tailored antibiotic therapy. Emphasis is placed on the role of immune status evaluation, drug concentration monitoring, and the necessity of long-term antimicrobial therapy. Improved clinician awareness and adherence to evidence-based management protocols are essential to achieving better outcomes in nocardiosis cases.</p>\",\"PeriodicalId\":23912,\"journal\":{\"name\":\"World Journal of Clinical Cases\",\"volume\":\"13 26\",\"pages\":\"108211\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336841/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Clinical Cases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12998/wjcc.v13.i26.108211\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Clinical Cases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12998/wjcc.v13.i26.108211","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Cutaneous nocardiosis in chronic renal insufficiency: Diagnostic and therapeutic considerations.
Nocardiosis remains a rare and often underdiagnosed bacterial infection, particularly in immunocompromised individuals. The case report by Zhang et al highlights the diagnostic and therapeutic challenges in managing Nocardia brasiliensis skin infection in a 93-year-old patient with chronic renal insufficiency. This editorial explores the importance of timely diagnosis, microbiological confirmation, and tailored antibiotic therapy. Emphasis is placed on the role of immune status evaluation, drug concentration monitoring, and the necessity of long-term antimicrobial therapy. Improved clinician awareness and adherence to evidence-based management protocols are essential to achieving better outcomes in nocardiosis cases.
期刊介绍:
The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.