腹膜后巨大脂肪肉瘤的思考与挑战:1例报告。

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Li-Li Cheng, Biao Tang, Hui Liu, Fan Zhu, Yi-Fa Chen, Wei Zhang
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引用次数: 0

摘要

背景:腹膜后脂肪肉瘤(RPLS)是一种罕见的起源于脂肪细胞的恶性肿瘤。由于其深层的解剖位置和潜伏的发病,只有当肿瘤很大时才会被发现。直径超过30厘米的巨型RPLS极为罕见。其诊断和治疗面临着极大的挑战。病例总结:患者,62岁女性,因腹胀6个多月来医院就诊。影像学检查显示腹膜后有一个大肿块。最后,患者被诊断为巨大的RPLS。肿瘤占据整个腹腔,严重压迫腹腔脏器,并与双侧输尿管紧密粘连。经过仔细的术前准备(包括三维可视化和双侧输尿管支架植入),我们对腹膜后肿物进行了切除。肿瘤完全切除,由多个肿块组成,总重量为17 kg,最大肿块尺寸为35 cm × 28 cm × 14 cm。术后病理结果显示肿块为高分化脂肪肉瘤。患者术后恢复良好,随访2个月无复发迹象。结论:手术切除是治疗巨大RPLS的唯一根治方法。术前准备是必不可少的,三维可视化重建有助于制定手术计划。术后放疗和新辅助治疗可合理选择,但是否能降低复发率仍存在争议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thoughts and challenges of giant retroperitoneal liposarcoma: A case report.

Background: Retroperitoneal liposarcoma (RPLS) is a rare malignant tumor initiated in adipocytes. It is discovered only when the tumor is large because of its deep anatomical location and insidious onset. Giant RPLS with a diameter exceeding 30 cm is extremely rare. Its diagnosis and treatment present extremely great challenges.

Case summary: The patient, a 62-year-old woman, presented to the hospital complaining of abdominal distension for more than six months. Imaging examination revealed a large retroperitoneal mass. Finally, the patient was diagnosed with giant RPLS. The tumor occupied the entire abdominal cavity, severely compressed the abdominal organs, and adhered tightly to the bilateral ureters. After careful preoperative preparation (including three-dimensional visualization and bilateral ureteral stent implantation), we performed resection of the large retroperitoneal mass. The tumor was completely removed and consisted of multiple masses, with a total weight of 17 kg and the largest mass size of 35 cm × 28 cm × 14 cm. Postoperative pathological results revealed that the mass was a well-differentiated liposarcoma. The patient recovered well after surgery, and there was no sign of recurrence after 2 months of follow-up.

Conclusion: Surgical resection is the only radical treatment for giant RPLS. Preoperative preparation is essential, and three-dimensional visualization reconstruction is helpful for the formulation of surgical plans. Postoperative radiotherapy and neoadjuvant therapy can be reasonably selected, but whether they can reduce the recurrence rate is still controversial.

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来源期刊
World Journal of Clinical Cases
World Journal of Clinical Cases Medicine-General Medicine
自引率
0.00%
发文量
3384
期刊介绍: The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.
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