Yi-Bing Wang, Xin-Xia Chen, Song-Tao Li, Hong-Ping Yan
{"title":"Effects of family cognitive therapy on aggressive behavior, family functioning, and marital quality in patients with major depression.","authors":"Yi-Bing Wang, Xin-Xia Chen, Song-Tao Li, Hong-Ping Yan","doi":"10.5498/wjp.v15.i3.101190","DOIUrl":"10.5498/wjp.v15.i3.101190","url":null,"abstract":"<p><strong>Background: </strong>Depression is a prevalent mental health disorder with significant impacts on individuals and families. We hypothesize that combining family cognitive therapy (FCT) with pharmacotherapy will be more effective in managing depression and improving family dynamics than pharmacotherapy alone.</p><p><strong>Aim: </strong>To investigate the effects of FCT combined with sertraline on depression, aggressive behavior, and family functioning in patients with major depressive disorder (MDD).</p><p><strong>Methods: </strong>This study involved 178 patients diagnosed with MDD at the Shaoxing 7th People's Hospital from January 2022 to April 2024. Patients were divided into two groups according to whether they received FCT. FCT included both patient-focused cognitive therapy and family-focused psychological guidance over a 12-week period.</p><p><strong>Results: </strong>The observation group receiving combined treatment showed significantly greater reductions in depressive symptoms (Beck Depression Inventory scores: 27.4 ± 4.7 to 18.6 ± 5.2) compared to the control group (28.1 ± 5.5 to 20.9 ± 4.9), with <i>P</i> = 0.031 for the difference between groups. Improvements in family functioning and marital quality were also observed, with <i>P</i> < 0.001 for key dimensions on the Family Assessment Device and Enrich Marital Scale.</p><p><strong>Conclusion: </strong>The combination of FCT with sertraline effectively reduces depressive symptoms and improves family dynamics in patients with MDD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101190"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing recovery in non-small cell lung cancer patients through mindfulness training and Jinshui Liujun decoction supplementation.","authors":"Haewon Byeon","doi":"10.5498/wjp.v15.i3.101876","DOIUrl":"10.5498/wjp.v15.i3.101876","url":null,"abstract":"<p><p>This article delves into the research conducted by Liu DW <i>et al</i> on the integration of mindfulness-based stress reduction training (MSRT) and flavored Jinshui Liujun decoction (FJLD) with conventional chemotherapy (CC) in the treatment of non-small cell lung cancer. The study investigates the impact of this combined approach on immune function and emotional well-being of non-small cell lung cancer patients. Patients were divided into a control group (CG) receiving CC alone and a treatment group (TG) receiving MSRT + FJLD alongside CC. The primary outcomes were progression-free survival and overall survival, with secondary outcomes including Karnofsky performance status scores, clinical efficacy, immune function markers, and emotional state assessments. The findings underscore significant improvements in median progression-free survival (20.50 months in TG <i>vs</i> 13.10 months in CG, <i>P</i> < 0.05), Karnofsky performance status scores (60 in TG <i>vs</i> 50 in CG, <i>P</i> < 0.05), and immune cell ratios, along with reductions in negative emotions (self-rating anxiety scale and self-rating depression scale scores significantly lower in TG, <i>P</i> < 0.05) among patients receiving MSRT + FJLD in conjunction with CC. This article highlights the potential of combining traditional Chinese medicine and modern psychological interventions to enhance the efficacy of conventional cancer treatments and improve patient outcomes.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101876"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Future anxiety mediates the relationship between organ donation and transplantation knowledge and health-related quality of life.","authors":"Amil Huseynov, Begum Satici","doi":"10.5498/wjp.v15.i3.103175","DOIUrl":"10.5498/wjp.v15.i3.103175","url":null,"abstract":"<p><strong>Background: </strong>Knowledge about organ donation and transplantation plays a crucial role in shaping individuals' health behaviors and perceptions, potentially impacting their health-related quality of life (HRQoL). Future anxiety, defined as the anticipatory worry individuals experience regarding potential negative events and outcomes in their future, may further influence these outcomes.</p><p><strong>Aim: </strong>To investigate the effect of such knowledge on HRQoL and to examine whether future anxiety mediates this relationship.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 659 participants aged 18 to 65 years. Participants completed the Organ Tissue Donation and Transplantation Knowledge Scale, the Dark Future Scale, and the European Health Interview Survey-Quality of Life 8. Correlation analyses were performed, followed by Structural Equation Modeling to test the proposed mediation model.</p><p><strong>Results: </strong>The findings indicated that greater knowledge about organ donation and transplantation was positively associated with higher HRQoL and negatively associated with future anxiety. Future anxiety was negatively correlated with HRQoL. Structural Equation Modeling analysis indicated that knowledge directly enhanced HRQoL and reduced future anxiety. Additionally, future anxiety negatively affected HRQoL, mediating the relationship between knowledge and HRQoL. The mediation effect was significant, as confirmed by bootstrapping (bootstrap coefficient = 0.068, 95%CI: 0.046-0.093).</p><p><strong>Conclusion: </strong>The study concludes that future anxiety partially mediates the positive impact of knowledge about organ donation and transplantation on HRQoL. These results suggest that increasing public knowledge in this area may reduce future anxieties and enhance quality of life.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103175"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identification of key brain networks and functional connectivities of successful aging: A surface-based resting-state functional magnetic resonance study.","authors":"Jiao-Jiao Sun, Li Zhang, Ru-Hong Sun, Xue-Zheng Gao, Chun-Xia Fang, Zhen-He Zhou","doi":"10.5498/wjp.v15.i3.100456","DOIUrl":"10.5498/wjp.v15.i3.100456","url":null,"abstract":"<p><strong>Background: </strong>Successful aging (SA) refers to the ability to maintain high levels of physical, cognitive, psychological, and social engagement in old age, with high cognitive function being the key to achieving SA.</p><p><strong>Aim: </strong>To explore the potential characteristics of the brain network and functional connectivity (FC) of SA.</p><p><strong>Methods: </strong>Twenty-six SA individuals and 47 usual aging individuals were recruited from community-dwelling elderly, which were taken the magnetic resonance imaging scan and the global cognitive function assessment by Mini Mental State Examination (MMSE). The resting state-functional magnetic resonance imaging data were preprocessed by DPABISurf, and the brain functional network was conducted by DPABINet. The support vector machine model was constructed with altered functional connectivities to evaluate the identification value of SA.</p><p><strong>Results: </strong>The results found that the 6 inter-network FCs of 5 brain networks were significantly altered and related to MMSE performance. The FC of the right orbital part of the middle frontal gyrus and right angular gyrus was mostly increased and positively related to MMSE score, and the FC of the right supramarginal gyrus and right temporal pole: Middle temporal gyrus was the only one decreased and negatively related to MMSE score. All 17 significantly altered FCs of SA were taken into the support vector machine model, and the area under the curve was 0.895.</p><p><strong>Conclusion: </strong>The identification of key brain networks and FC of SA could help us better understand the brain mechanism and further explore neuroimaging biomarkers of SA.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100456"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng-Guang Zhang, Yu Zhang, Ke Xu, Shun Wang, Yan Bai
{"title":"Correlation of inflammatory markers with depression and sleep disorders accompanying the prodromal stage of Parkinson's disease.","authors":"Cheng-Guang Zhang, Yu Zhang, Ke Xu, Shun Wang, Yan Bai","doi":"10.5498/wjp.v15.i3.99901","DOIUrl":"10.5498/wjp.v15.i3.99901","url":null,"abstract":"<p><p>Parkinson's disease (PD) is a common neurodegenerative disorder with increasing incidence and disability rates globally, placing a heavy burden on patients and their families. In the prodromal phase of PD, nonmotor symptoms, particularly depression and sleep disorders, are frequent, with profound effects on disease progression and patient quality of life. Emerging research highlights the critical role of inflammatory markers-including interleukins and tumor necrosis factor-in the pathogenesis of prodromal PD. These inflammatory mediators participate in neurodegenerative processes and may induce or exacerbate depressive symptoms and sleep disorders by disrupting the function of the hypothalamic-pituitary-adrenal axis and affecting neurotransmitter, including serotonin, metabolism. Understanding their correlations with nonmotor symptoms in prodromal PD remains incomplete, limiting our ability to develop targeted interventions. This comprehensive review aims to investigate the specific correlations between inflammatory markers and nonmotor symptoms-particularly depression and sleep disorders-in prodromal PD. The findings could have important practical applications, potentially leading to the development of new diagnostic tools and therapeutic strategies for managing PD. By identifying and understanding these correlations, healthcare providers may better predict disease progression and implement more effective treatments for nonmotor symptoms in PD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99901"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Voxel-based alterations in spontaneous brain activity among very-late-onset schizophrenia-like psychosis: A preliminary resting-state functional magnetic resonance imaging study.","authors":"Dan-Ting Yang, Ping Ji, Jiao-Jiao Sun, Yan-Sha Gan, Shuai-Yi Guo, Zhen-He Zhou, Xue-Zheng Gao","doi":"10.5498/wjp.v15.i3.101494","DOIUrl":"10.5498/wjp.v15.i3.101494","url":null,"abstract":"<p><strong>Background: </strong>Very late-onset schizophrenia-like psychosis (VLOSLP) is a subtype of schizophrenia spectrum disorders in which individuals experience psychotic symptoms for the first time after the age of 60. The incidence of VLOSLP shows a linear relationship with increasing age. However, no studies have reported alterations in spontaneous brain activity among VLOSLP patients and their correlation with cognitive function and clinical symptoms.</p><p><strong>Aim: </strong>To explore VLOSLP brain activity and correlations with cognitive function and clinical symptoms using resting-state functional magnetic resonance imaging.</p><p><strong>Methods: </strong>This study included 33 VLOSLP patients and 34 healthy controls. The cognitive assessment utilized the Mini Mental State Examination, Montreal Cognitive Assessment, and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Clinical characteristic acquisition was performed <i>via</i> the Positive and Negative Syndrome Scale (PANSS). All participants were scanned <i>via</i> resting-state functional magnetic resonance imaging, and the data were processed using amplitude of low-frequency fluctuations (ALFF), fractional ALFF (fALFF), regional homogeneity, and voxel-mirrored homotopic connectivity (VMHC).</p><p><strong>Results: </strong>The VLOSLP group presented decreased ALFF values in the left cuneus, right precuneus, right precentral gyrus, and left paracentral lobule; increased fALFF values in the left caudate nucleus; decreased fALFF values in the right calcarine fissure and surrounding cortex (CAL) and right precuneus; increased regional homogeneity values in the right putamen; and decreased VMHC values in the bilateral CAL, bilateral superior temporal gyrus, and bilateral cuneus. In the VLOSLP group, ALFF values in the right precuneus were negatively correlated with Mini Mental State Examination score and PANSS positive subscale score, and VMHC values in the bilateral CAL were negatively correlated with the RBANS total score, RBANS delayed memory score, and PANSS positive subscale score.</p><p><strong>Conclusion: </strong>The changes of brain activity in VLOSLP are concentrated in the right precuneus and bilateral CAL regions, which may be associated with cognitive impairment and clinically positive symptoms.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101494"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selective serotonin reuptake inhibitors in the treatment of major depressive disorder after brain trauma: Systematic review and meta-analysis.","authors":"Ren-Xian Gao, Xiao-Na Zhang, Peng Zhu","doi":"10.5498/wjp.v15.i3.100103","DOIUrl":"10.5498/wjp.v15.i3.100103","url":null,"abstract":"<p><strong>Background: </strong>Traumatic brain injury (TBI) poses a considerable risk to human health. After TBI, individuals are susceptible to a range of psychiatric disorders, with depression being a primary complication. Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment of depression; however, their efficacy in addressing major depressive disorder (MDD) in adults following TBI remains uncertain.</p><p><strong>Aim: </strong>To investigate the efficacy of SSRIs in the treatment of MDD after TBI.</p><p><strong>Methods: </strong>A comprehensive search across multiple databases was conducted following the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, encompassing studies published until May 2024. This review focused on studies that examined the efficacy of SSRIs in the treatment of MDD following TBI. Studies were assessed based sample size, treatment duration, treatment methodologies, severity of brain injury, assessment techniques, and drug response. A random-effects model was used to derive the summary effect size.</p><p><strong>Results: </strong>Eight studies compared the reduction in depression scores in patients with MDD after TBI and SSRI treatment. The eight studies did not exhibit heterogeneity (<i>I</i> <sup>2</sup> = 38%). The depression score for MDD after TBI in the SSRI group decreased more than that in the control group [odds ratio (OR) 1.68, 95%CI: 1.09-2.58, <i>P</i> = 0.02]. The adverse reactions after treatment included diarrhea, dizziness, dry mouth, nausea, or vomiting. There was no difference in the incidence of adverse reactions after treatment between the two groups (OR 1.16, 95%CI: 0.78-1.73, <i>P</i> = 0.46]. These studies did not show significant heterogeneity (<i>I</i> <sup>2</sup> = 44%).</p><p><strong>Conclusion: </strong>SSRIs may be effective in treating patients with MDD after TBI. Adequately powered, randomized, controlled trials are required to confirm these findings.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100103"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can decoding the complex web of non-suicidal self-injury in adolescents pave the way for tailored interventions?","authors":"Haewon Byeon","doi":"10.5498/wjp.v15.i3.103258","DOIUrl":"10.5498/wjp.v15.i3.103258","url":null,"abstract":"<p><p>Non-suicidal self-injury (NSSI) is a prevalent and concerning issue in adolescent mental health, often intertwined with depressive symptoms. Despite extensive research on NSSI, a comprehensive understanding of its multifaceted nature and the intricate interplay of risk and resilience factors remains crucial. This Letter to the Editor examines a novel study by Yang <i>et al</i>, which utilized latent profile analysis and network analysis to delineate distinct NSSI subtypes within a Chinese adolescent population and investigate the underlying dynamics of associated factors. The study identifies three distinct NSSI subtypes: NSSI with depression, NSSI without depression, and neither, underscoring bullying as a prominent risk factor. Concurrently, the findings emphasized the pivotal role of emotional regulation and family support as protective factors. The focus of this article is to contextualize these findings within the broader framework of adolescent mental health and to highlight their implications for developing targeted interventions. These insights not only advance our understanding of adolescent NSSI but also provide a foundation for the development of targeted interventions that address the identified risk and protective factors. By focusing on these critical areas, mental health professionals can implement more effective strategies to mitigate NSSI behaviors and cultivate resilience in this vulnerable population.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103258"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Impact of comorbid subthreshold depressive symptoms on cancer-related fatigue and complications in adults with leukemia.","authors":"Yue-Xian Liu, Juan Wang","doi":"10.5498/wjp.v15.i3.103446","DOIUrl":"10.5498/wjp.v15.i3.103446","url":null,"abstract":"<p><p>[This corrects the article on p. 1009 in vol. 14, PMID: 39050202.].</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103446"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychological consistency network characteristics and influencing factors in patients after percutaneous coronary intervention treatment.","authors":"Yue Li, Liang-Hong Wang, Huan Zeng, Yan Zhao, Yao-Qiong Lu, Tian-Ying Zhang, Hai-Bin Luo, Feng Tang","doi":"10.5498/wjp.v15.i3.102571","DOIUrl":"10.5498/wjp.v15.i3.102571","url":null,"abstract":"<p><strong>Background: </strong>A psychological sense of coherence (SOC) in percutaneous coronary intervention (PCI) patients is important for disease prognosis, and there is considerable variation between their symptoms. In contrast, network analysis provides a new approach to gaining insight into the complex nature of symptoms and symptom clusters and identifying core symptoms.</p><p><strong>Aim: </strong>To explore the psychological coherence of symptoms experienced by PCI patients, we aim to analyze differences in their associated factors and employ network analysis to characterize the symptom networks.</p><p><strong>Methods: </strong>A total of 472 patients who underwent PCI were selected for a cross-sectional study. The objective was to investigate the association between general patient demographics, medical coping styles, perceived stress status, and symptoms of psychological coherence. Data analysis was conducted using a linear regression model and a network model to visualize psychological coherence and calculate a centrality index.</p><p><strong>Results: </strong>Post-PCI patients exhibited low levels of psychological coherence, which correlated with factors such as education, income, age, place of residence, adherence to medical examinations, perceived stress, and medical coping style. Network analysis revealed that symptoms within the sense of psychological coherence were strongly interconnected, particularly with SOC2 and SOC8, demonstrating the strongest correlations. Among these, SOC10 emerged as the symptom with the highest intensity, centrality, and proximity, identifying it as the most central symptom.</p><p><strong>Conclusion: </strong>The network model has strong explanatory power in describing the psychological consistency symptoms of patients after PCI, identifying the central SOC symptoms, among which SOC10 is the key to overall SOC enhancement, and there is a strong positive correlation between SOC2 and SOC8, emphasizing the need to consider the synergistic effect of symptoms in intervention measures.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102571"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}