World Journal of Psychiatry最新文献

{"title":"Global research status and trends of somatic symptom disorder: A bibliometric study.","authors":"Chao Yang, Kun Zhang, Qian Wang, Shuai Wang, Huan Li, Kai Zhang","doi":"10.5498/wjp.v15.i1.100730","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.100730","url":null,"abstract":"<p><strong>Background: </strong>With the growing scholarly and clinical fascination with somatic symptom disorder (SSD), a bibliometric analysis is lacking.</p><p><strong>Aim: </strong>To conduct a bibliometric analysis to investigate the current status and frontiers of SSD.</p><p><strong>Methods: </strong>The documents related to SSD are obtained from the web of science core collection database (WoSCC), and VOSviewer 1.6.16 from January 1, 2000 to December 31, 2023, and the WoSCC's literature analysis wire were used to conduct the bibliometric analysis.</p><p><strong>Results: </strong>A total of 567 documents related to SSD were included, and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research, published in 277 journals. The most productive author, institution, country and journal were Löwe B, University of Hamburg, Germany, and <i>Journal of Psychosomatic Research</i> respectively. The first high-cited document was published in the <i>Journal of Psychosomatic Research</i> in 2013 by Dimsdale JE and colleagues, which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental disorders.</p><p><strong>Conclusion: </strong>In conclusion, the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria, functional impairment of SSD, and the treatment for SSD. More high-quality studies are needed to assess the diagnosis and treatment of SSD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"100730"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures.","authors":"Bo Wang, Da Shi, Yin-Di Sun, Bo Dong","doi":"10.5498/wjp.v15.i1.101373","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.101373","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Traumatic injuries, such as falling, car accidents, and crushing mostly cause spinal fractures in young and middle-aged people, and &gt; 50% of them are thoracolumbar fractures. This kind of fracture is easily combined with serious injuries to peripheral nerves and soft tissues, which causes paralysis of the lower limbs if there is no timely rehabilitation treatment. Young patients with thoracolumbar fractures find it difficult to recover after the operation, and they are prone to depression, low self-esteem, and other negative emotions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To investigate the association between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures and the effect on rehabilitation outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study retrospectively analyzed 100 patients admitted to the orthopedic department of Honghui Hospital, Xi'an Jiaotong University who underwent thoracolumbar spine fracture surgery from January 2022 to June 2023. The general data of the patients were assessed with the Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD), life events scale, and social support rating scale (SSRS) to identify the correlation between anxiety, depression scores, and social stress and social support. The Japanese Orthopedic Association (JOA) was utilized to evaluate the rehabilitation outcomes of the patients and to analyze the effects of anxiety and depression scores on rehabilitation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;According to the scores of HAMD and HAMA in all patients, the prevalence of depression in patients was 39% (39/100), and the prevalence of anxiety was 49% (49/100). Patients were categorized into non-depression (&lt;i&gt;n&lt;/i&gt; = 61) and depression (&lt;i&gt;n&lt;/i&gt; = 39), non-anxiety (&lt;i&gt;n&lt;/i&gt; = 51), and anxiety (&lt;i&gt;n&lt;/i&gt; = 49) groups. Statistically significant differences in gender, occupation, Pittsburgh Sleep Quality Index (PSQI) score, and monthly family income were observed between the non-depression and depression groups (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). A significant difference in occupation and PSQI score was found between the non-anxiety and anxiety groups. Both depression (&lt;i&gt;r&lt;/i&gt; = 0.207, &lt;i&gt;P&lt;/i&gt; = 0.038) and anxiety scores (&lt;i&gt;r&lt;/i&gt; = 0.473, &lt;i&gt;P&lt;/i&gt; &lt; 0.001) were significantly and positively correlated with negative life events. The difference in negative life event scores as well as SSRS total and item scores was statistically significant between patients in the non-depression and depression groups (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). The difference between the non-anxiety and anxiety groups was statistically significant (&lt;i&gt;P&lt;/i&gt; &lt; 0.05) in the negative life event scores as well as the total SSRS scores. Additionally, JOA scores were significantly lower in both anxious and depressed patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Young patients with thoracolumbar fractures are prone to anxiety and depression. Patients' anxiety and depression are closely associated with social press","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"101373"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and prospect of near-infrared spectroscopy-assisted schizophrenia diagnosis based on bibliometrics.","authors":"Yan Zhang, Hao-Yu Xing, Juan Yan","doi":"10.5498/wjp.v15.i1.100791","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.100791","url":null,"abstract":"<p><p>In this editorial, we comment on the recent article by Fei <i>et al</i> exploring the field of near-infrared spectroscopy (NIRS) research in schizophrenia from a bibliometrics perspective. In recent years, NIRS has shown unique advantages in the auxiliary diagnosis of schizophrenia, and the introduction of bibliometrics has provided a macro perspective for research in this field. Despite the opportunities brought about by these technological developments, remaining challenges require multidisciplinary approach to devise a reliable and accurate diagnosis system for schizophrenia. Nonetheless, NIRS-assisted technology is expected to contribute to the division of methods for early intervention and treatment of schizophrenia.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"100791"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motivational interviewing in postoperative rehabilitation and chronic disease management: Current findings and future research directions.","authors":"Bing-Ren Zhang, Xiao Yang","doi":"10.5498/wjp.v15.i1.102737","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.102737","url":null,"abstract":"<p><p>This editorial highlights a recently published study examining the effectiveness of music therapy combined with motivational interviewing (MI) in addressing anxiety and depression among young and middle-aged patients following percutaneous coronary intervention. It further explores existing evidence and potential future research directions for MI in postoperative rehabilitation and chronic disease management. MI aims to facilitate behavioral change and promote healthier lifestyles by fostering a trusting relationship with patients and enhancing intrinsic motivation. Research has demonstrated its effectiveness in postoperative recovery for oncological surgery, stroke, organ transplants, and gastrointestinal procedures, as well as in managing chronic conditions such as diabetes, obesity, and periodontal disease. The approach is patient-centered, adaptable, cost-effective, and easily replicable, though its limitations include reliance on the therapist's expertise, variability in individual responses, and insufficient long-term follow-up studies. Future research could focus on developing individualized and precise intervention models, exploring applications in digital health management, and confirming long-term outcomes to provide more comprehensive support for patient rehabilitation.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"102737"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative efficacy of antidepressants in pharmacotherapy of child and adolescent depression.","authors":"Min Xu, Hai-Ying Jin, Feng-Li Sun, Wei-Dong Jin","doi":"10.5498/wjp.v15.i1.100308","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.100308","url":null,"abstract":"<p><p>Antidepressants are the main drugs used to treat depression, but they have not been shown to be effective in the treatment of child and adolescent depression. However, many adolescent depression treatment guidelines still recommend the use of antidepressants, especially specific serotonin re-uptake inhibitors. Previous studies have suggested that antidepressants have little therapeutic effect but many side effects, such as switching to mania, suicide, and non-suicidal self injury (NSSI), in the treatment of child and adolescent depression. In the process of developing guidelines, drug recommendations should not only focus on improving symptoms, but they should also consider potential side effects. This review discusses the serious side effects of antidepressants, including switching to mania, suicide, and NSSI.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"100308"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions and emotions in postoperative recovery of patients with perianal diseases.","authors":"Bryan Adrian Priego-Parra, Jose Maria Remes-Troche","doi":"10.5498/wjp.v15.i1.101563","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.101563","url":null,"abstract":"<p><p>This article examines the complex relationship between disease perception, negative emotions, and their impact on postoperative recovery in patients with perianal diseases. These conditions not only cause physical discomfort, but also carry a significant emotional burden, often exacerbated by social stigma. Psychological factors, including stress, anxiety, and depression, activate neuroendocrine pathways, such as the hypothalamic-pituitary-adrenal axis, disrupting the gut microbiota and leading to dysbiosis. This disruption can delay wound healing, prolong hospital stay, and intensify pain. Drawing on the findings of Hou <i>et al</i>, our article highlights the critical role of illness perception and negative emotions in shaping recovery outcomes. It advocates for a holistic approach that integrates psychological support and gut microbiota modulation, to enhance healing and improve overall patient outcomes.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"101563"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of stent thrombectomy and conventional treatment with neuroprotection, complications, anxiety, and depression in acute ischemic stroke patients.","authors":"Kai-Jie Yang, Jia-Jian Huang, Cai-Xia Xuan","doi":"10.5498/wjp.v15.i1.101182","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.101182","url":null,"abstract":"<p><strong>Background: </strong>Acute ischemic stroke (AIS) is an abrupt blood flow cessation to a specific brain region within a vascular zone, causing a subsequent decline in neurological capabilities. Stent thrombectomy is a recently established technique for treating AIS. It provides the benefits of being a relatively simple and safe procedure, capable of partially enhancing a patient's condition. However, some patients may experience endothelial damage and recurrent thrombosis, with clinical outcomes that are not always satisfactory. Hence, the efficacy of this method remains unclear.</p><p><strong>Aim: </strong>To survey the association of stent thrombectomy <i>vs</i> standard treatment with neurological function protection, complications, and short-term prognosis in patients diagnosed with AIS.</p><p><strong>Methods: </strong>This study assigned 90 patients with AIS to the observation and control groups (<i>n</i> = 45 patients) from December 2020 to December 2022. Stent thrombectomy was conducted in the observation group, whereas routine treatment was provided to the control group. The study assessed the therapeutic outcomes of two groups, including a comparison of their neurological function, living ability, anxiety and depression status, plaque area, serum inflammatory factors, serum Smur100 β protein, neuron-specific enolase (NSE), homocysteine (Hcy), and vascular endothelial function. Additionally, the incidence of complications was calculated and analyzed for each group.</p><p><strong>Results: </strong>The total effective rate of treatment was 77.78% and 95.56% in the control and observation groups, respectively. After 8 weeks of treatment, the scores on the National Institutes of Health Stroke Scale, Hamilton Anxiety Scale, and Hamilton Depression Scale decreased remarkably; the Barthel index increased remarkably, with better improvement effects of the scores in the observation group (<i>P</i> < 0.05); total cholesterol, triglyceride, C-reactive protein, and plaque area lessened remarkably, with fewer patients in the observation group (<i>P</i> < 0.05); S-100β protein, NSE, and Hcy levels lessened remarkably, with fewer patients in the observation group (<i>P</i> < 0.05); serum vascular endothelial growth factor and nitric oxide synthase levels increased remarkably, whereas the endothelin-1 level decreased, with better improvement effect in the observation group (<i>P</i> < 0.05). Complications occurred in 8.88% of patients in the observation group compared with 33.33% in the control group.</p><p><strong>Conclusion: </strong>Stent thrombectomy appeared to provide more remarkable neuroprotective effects in patients with AIS compared to the intravenous thrombolysis regimen. Additionally, it has effectively improved the neurological function, daily activities, and vascular endothelial function of patients, while reducing the incidence of complications and improving short-term prognosis.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"101182"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression.","authors":"Juan Liu, Yan-Ping Guo, Yan-Mei Lu, Bei-Lin Wang","doi":"10.5498/wjp.v15.i1.98737","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.98737","url":null,"abstract":"<p><strong>Background: </strong>Urinary system tumors often cause negative psychological symptoms, such as depression and dysphoria which significantly impact immune function and indirectly affect cancer prognosis. While epirubicin (EPI) is recommended by the European Association of Urology and can improve prognosis, its long-term use can cause toxic side effects, reduce treatment compliance, and increase psychological burden. Therefore, an appropriate intervention mode is necessary.</p><p><strong>Aim: </strong>To explore the clinical value of EPI combined with mindfulness intervention in patients with urinary system tumors and depression.</p><p><strong>Methods: </strong>This was a retrospective study including 110 patients with urinary system tumors and depression admitted to Zhumadian Central Hospital between March 2021 and July 2023. Patients were divided into conventional (<i>n</i> = 55) and joint intervention (<i>n</i> = 55) groups. The conventional group received mitomycin and routine nursing, while the joint intervention group received EPI and mindfulness intervention. Both groups underwent three cycles of chemotherapy. Immune function (CD4+ cells, CD8+ cells, CD4+/CD8+ ratio), tumor marker levels [urinary bladder cancer antigen (UBC), bladder tumor antigen (BTA) and nuclear matrix protein 22 (NMP22)], quality of life questionnaire-core 30 (QLQ-C30), 17-item Hamilton depression scale (HAMD-17), and cancer-related fatigue [cancer fatigue scale (CFS)] were assessed. Adverse reactions and nursing satisfaction were recorded and evaluated.</p><p><strong>Results: </strong>Post-intervention, CD4+, CD8+, and CD4+/CD8+ levels increased in both groups, with the joint intervention group showing more significant improvement (<i>P</i> < 0.05). Tumor marker levels (NMP22, BTA, and UBC) were lower in the joint intervention group compared to the conventional group (<i>P</i> < 0.05). The joint intervention group also showed a greater reduction in HAMD-17 scores (9.38 ± 3.12 <i>vs</i> 15.45 ± 4.86, <i>P</i> < 0.05), higher QLQ-C30 scores, and lower CFS scores (both <i>P</i> < 0.05). Additionally, the joint intervention group had a lower incidence of adverse reactions and higher nursing satisfaction (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>EPI combined with mindfulness intervention significantly improved clinical outcomes in patients with urinary system tumors and depression and is worthy of clinical application.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"98737"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders: Present trends and future directions.","authors":"Bo-Fan Chen, Li Liu, Fang-Zhen Lin, Hai-Min Zeng, Hai-Qiang Huang, Chun-Fang Zhang, Cong-Cong Liu, Xiang Chen, Jie Peng, Yun-Fa Wang, Zhi-Lin Wang, Bin Chen, De-Le Liu, Yun Liu, Zheng-Zheng Li, Xin-Xing Zeng","doi":"10.5498/wjp.v15.i1.100685","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.100685","url":null,"abstract":"<p><strong>Background: </strong>Bipolar disorder (BD) is a severe mental illness characterized by significant mood swings. Effective drug treatment modalities are crucial for managing BD.</p><p><strong>Aim: </strong>To analyze the current status and future trends of global research on BD drug treatment over the last decade.</p><p><strong>Methods: </strong>The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment. A total of 2624 articles were extracted. Data visualization and analysis were conducted using CiteSpace, VOSviewer, Pajek, Scimago Graphica, and R-studio bibliometrix to identify research hotspots, key contributors, and future trends.</p><p><strong>Results: </strong>The United States, China, and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks. The University of Pittsburgh, Massachusetts General Hospital, and the University of Michigan have been identified as the major research institutions in this field. The <i>Journal of Affective Disorders</i> is the most influential journal. A keyword analysis revealed research hotspots related to clinical symptoms, drug efficacy, and genetic mechanisms. A citation analysis identified the management guidelines published by Yatham <i>et al</i> in 2018 as the most cited paper.</p><p><strong>Conclusion: </strong>This study provides a detailed overview of the field of BD drug treatment, highlighting key contributors, research hotspots, and future directions. The study findings can be employed as a reference for future research and policymaking, which may enable further development and optimization of BD pharmacotherapy.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"100685"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating role of health literacy in the relationship between social isolation and psychological distress among pre-frail older adults.","authors":"Juan Fang, Li-Hui Li, Ming-Qian He, Yue Ji, Dong-Yan Lu, Li-Bing Zhang, Jin-Lan Yao","doi":"10.5498/wjp.v15.i1.100953","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.100953","url":null,"abstract":"<p><strong>Background: </strong>Frailty has become a significant public health issue. The recent increase in the number of frail older adults has led to increased attention being paid to psychological care services in communities. The social isolation of pre-frail older adults can impact their psychological distress.</p><p><strong>Aim: </strong>To explore the mediating effect of health literacy between social isolation and psychological distress among communitydwelling older adults with pre-frailty.</p><p><strong>Methods: </strong>This descriptive cross-sectional study was conducted with 254 pre-frail older individuals aged 60 years and over. Social isolation, health literacy, and psychological distress were comprehensively measured using the Lubben Social Network Scale-6, 12-item Short-Form Health Literacy Questionnaire, and the Kessler Psychological Distress Scale-10. Data were evaluated using the SPSS 27.0 package program and the PROCESS macro tool. Descriptive statistical analyses, correlation analyses, and bootstrap mediation tests were used to assess associations between the variables.</p><p><strong>Results: </strong>The results showed that social isolation had an effect on health literacy among pre-frail older adults (<i>β</i> = 0.240, <i>P</i> < 0.001), social isolation impact on psychological distress pre-frail older adults (<i>β</i> = -0.415, <i>P</i> < 0.001); health literacy was identified effect on psychological distress among pre-frail older persons (<i>β</i> = -0.307, <i>P</i> < 0.001). Health literacy partially mediated the relationship between social isolation and psychological distress among community-dwelling older adults with pre-frailty, with a mediation effect of -0.074, accounting for 17.83% of the total effect.</p><p><strong>Conclusion: </strong>Health literacy significantly affects the relationship between social isolation and psychological distress among pre-frail older adults. Apart from fostering social connections, improved health literacy measures should be considered.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"100953"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}