World Journal of Psychiatry最新文献

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Gender-based economic violence and the exploitation of women: A deep dive.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.103725
Elif Sarac, Deniz Odabas
{"title":"Gender-based economic violence and the exploitation of women: A deep dive.","authors":"Elif Sarac, Deniz Odabas","doi":"10.5498/wjp.v15.i3.103725","DOIUrl":"10.5498/wjp.v15.i3.103725","url":null,"abstract":"<p><p>Economic violence is a form of domestic violence that extends beyond physical harm, affecting victims' economic stability and independence. This situation perpetuates gender inequality and also reinforces the cycle of gender-based violence. With definitions of economic violence broadening to encompass a range of coercive and manipulative behaviors - from financial abuse in domestic violence scenarios to the economic harassment faced by stay-at-home moms - understanding this form of exploitation is crucial for crafting effective interventions. This article aims to delve into various facets of economic violence, including its definition, prevalence, and the stark realities it creates for its victims. Following the search of international databases: Social Work Abstracts (EBSCO), Psychology Abstracts, Family and Women Studies Worldwide, Psychiatry Online, Psych INFO (including Psych ARTICLES), PubMed, Wiley, and Scopus, 60 peer-reviewed articles that met all inclusion criteria were included in the paper. Our review clarifies that looking forward, the call for a comprehensive understanding of economic violence, enhanced legal frameworks, and the strengthening of supportive networks underscore the multidisciplinary approach required to combat this issue effectively.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103725"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of lattice CO2 laser combined with Kegel exercise mild moderate stress urinary incontinence and postpartum depression anxiety.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.103252
Zhao-Xia Lou, Shu-Ying Huang, Ze-Qiu Wan, Yun Chen, Hua-Ying Shan, Ling-Yan Wang
{"title":"Effect of lattice CO<sub>2</sub> laser combined with Kegel exercise mild moderate stress urinary incontinence and postpartum depression anxiety.","authors":"Zhao-Xia Lou, Shu-Ying Huang, Ze-Qiu Wan, Yun Chen, Hua-Ying Shan, Ling-Yan Wang","doi":"10.5498/wjp.v15.i3.103252","DOIUrl":"10.5498/wjp.v15.i3.103252","url":null,"abstract":"<p><strong>Background: </strong>Postpartum stress urinary incontinence (SUI) symptoms affect a patient's daily activities and quality of life and increase the negative emotions that they experience. At present, there is no research on the effect of fractional CO<sub>2</sub> laser treatment combined with Kegel exercise on postpartum SUI and postpartum depression and anxiety.</p><p><strong>Aim: </strong>To investigate the effect of lattice CO<sub>2</sub> laser treatment combined with Kegel exercise on mild to moderate postpartum SUI and its influence on postpartum depression and anxiety.</p><p><strong>Methods: </strong>Using a retrospective study, data from 82 cases of mild to moderate postpartum SUI in Huzhou Maternal & Child Health Care Hospital from January to April 2024 were retrospectively collected. The cases were divided into groups according to the different treatment methods, namely Group S (41 cases, only receiving lattice CO<sub>2</sub> laser treatment) and Group L (41 cases, receiving lattice CO<sub>2</sub> laser combined with Kegel exercise treatment). The baseline data of the two groups were compared. In addition, we analyzed and compared the scores of the international commission on urinary incontinence questionnaire short form (ICI-Q-SF), incontinence quality of life questionnaire (I-QOL), Edinburgh postnatal depression scale (EPDS), and postpartum specific anxiety scale (PSAS) before treatment, at the end of treatment, and 3 months after the end of treatment between the two groups. Furthermore, the clinical efficacy and adverse reactions of the two groups were analyzed and compared at the end of treatment and 3 months after the end of treatment.</p><p><strong>Results: </strong>There was no significant difference in the baseline data and the ICI-Q-SF, I-QOL, EPDS, and PSAS scores between the two groups before treatment. However, at the end of treatment, the ICI-Q-SF, I-QOL, EPDS, and PSAS scores between Groups L and S were significantly different. The overall effective rate of treatment in Group L was significantly higher than that in Group S. During the 3-month follow-up after treatment, it was found that the ICI-Q-SF, EPDS, and PSAS scores of Group L were still lower than those of Group S. In comparison, the I-QOL score and total effective rate of treatment were still higher in Group L than those in Group S, and this difference was significant. There was no significant difference in the adverse reactions between Group L and Group S.</p><p><strong>Conclusion: </strong>The combination of dot lattice CO<sub>2</sub> laser and Kegel exercise has a significant therapeutic effect on mild to moderate postpartum SUI. It can prolong the duration of therapeutic effects, improve a patient's quality of life, and alleviate postpartum depression and anxiety.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103252"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of ADIET communication and delivery rehearsal on anxiety, labor process, and outcomes in vaginal trial delivery.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.99509
Ling-Mei Liu, Hao-Yu He, Jing-Xian Lu
{"title":"Effects of ADIET communication and delivery rehearsal on anxiety, labor process, and outcomes in vaginal trial delivery.","authors":"Ling-Mei Liu, Hao-Yu He, Jing-Xian Lu","doi":"10.5498/wjp.v15.i3.99509","DOIUrl":"10.5498/wjp.v15.i3.99509","url":null,"abstract":"<p><strong>Background: </strong>In recent years, the obstetrics department has advocated vaginal delivery to reduce the rate of cesarean sections. However, in clinical practice, pregnant women are prone to anxiety before childbirth, making it difficult to perform a vaginal trial delivery smoothly. The combined approach of ADIET communication and delivery rehearsal for vaginal trial delivery can provide a reference for reducing prenatal anxiety, shortening labor duration, facilitating a smooth delivery, and ensuring the safety of both mothers and babies.</p><p><strong>Aim: </strong>To analyze the effect of AIDET communication combined with labor rehearsal on vaginal trial delivery.</p><p><strong>Methods: </strong>A study conducted between January 2023 and December 2023 included 200 vaginal trials. Women were randomly assigned to an observation group (100 women), which received ADIET communication plus delivery intervention, and a control group (100 women), which received routine communication plus delivery intervention. This study aimed to compare antenatal anxiety status as measured using the Maternal Anxiety Scale, labor duration, delivery efficacy as assessed using the simplified Chinese version of the Childbirth Self-Efficacy Inventory, and delivery outcomes.</p><p><strong>Results: </strong>After the intervention, the observation group had a lower Maternal Anxiety Scale score and higher Childbirth Self-Efficacy Inventory score (<i>P</i> < 0.05) than the control group (<i>P</i> < 0.05), whereas the observation group had higher natural delivery, cesarean delivery, vaginal delivery, and neonatal asphyxia rates (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>For women undergoing vaginal trial delivery, a combination of AIDET communication and delivery rehearsal can relieve prenatal anxiety, enhance delivery efficiency, shorten labor duration, and somewhat improve delivery outcomes.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99509"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding patients' emotional needs to strengthen therapeutic relationships: A deep insight into narrative nursing.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.103093
Wen-Jue Pan, Shu-Fen Wang
{"title":"Understanding patients' emotional needs to strengthen therapeutic relationships: A deep insight into narrative nursing.","authors":"Wen-Jue Pan, Shu-Fen Wang","doi":"10.5498/wjp.v15.i3.103093","DOIUrl":"10.5498/wjp.v15.i3.103093","url":null,"abstract":"<p><p>Narrative nursing has emerged as a vital approach in patient-centered care, and emphasize the importance of understanding patients' emotional experiences in addition to their physical health needs. In this article, we comment on the article by Zhou <i>et al</i>. Diseases such as acute pancreatitis can cause significant suffering and severely impact patients' quality of life. During treatment, routine nursing procedures such as gastric tube placement, oxygen therapy, monitoring, and nasogastric feeding often lack effective communication, which can adversely affect patients' recovery. This article highlights how narrative nursing can provide deeper insights into patients' emotional experiences, ultimately resulting in improved care outcomes. We also emphasize the role of narrative nursing in understanding and addressing these emotional needs to achieve personalized care, which can strengthen the therapeutic relationship between healthcare providers and patients. By recognizing the critical role of emotional well-being in patient care, we can develop comprehensive strategies that facilitate recovery and enhance overall quality of life.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103093"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of family cognitive therapy on aggressive behavior, family functioning, and marital quality in patients with major depression.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.101190
Yi-Bing Wang, Xin-Xia Chen, Song-Tao Li, Hong-Ping Yan
{"title":"Effects of family cognitive therapy on aggressive behavior, family functioning, and marital quality in patients with major depression.","authors":"Yi-Bing Wang, Xin-Xia Chen, Song-Tao Li, Hong-Ping Yan","doi":"10.5498/wjp.v15.i3.101190","DOIUrl":"10.5498/wjp.v15.i3.101190","url":null,"abstract":"<p><strong>Background: </strong>Depression is a prevalent mental health disorder with significant impacts on individuals and families. We hypothesize that combining family cognitive therapy (FCT) with pharmacotherapy will be more effective in managing depression and improving family dynamics than pharmacotherapy alone.</p><p><strong>Aim: </strong>To investigate the effects of FCT combined with sertraline on depression, aggressive behavior, and family functioning in patients with major depressive disorder (MDD).</p><p><strong>Methods: </strong>This study involved 178 patients diagnosed with MDD at the Shaoxing 7th People's Hospital from January 2022 to April 2024. Patients were divided into two groups according to whether they received FCT. FCT included both patient-focused cognitive therapy and family-focused psychological guidance over a 12-week period.</p><p><strong>Results: </strong>The observation group receiving combined treatment showed significantly greater reductions in depressive symptoms (Beck Depression Inventory scores: 27.4 ± 4.7 to 18.6 ± 5.2) compared to the control group (28.1 ± 5.5 to 20.9 ± 4.9), with <i>P</i> = 0.031 for the difference between groups. Improvements in family functioning and marital quality were also observed, with <i>P</i> < 0.001 for key dimensions on the Family Assessment Device and Enrich Marital Scale.</p><p><strong>Conclusion: </strong>The combination of FCT with sertraline effectively reduces depressive symptoms and improves family dynamics in patients with MDD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101190"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing recovery in non-small cell lung cancer patients through mindfulness training and Jinshui Liujun decoction supplementation.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.101876
Haewon Byeon
{"title":"Enhancing recovery in non-small cell lung cancer patients through mindfulness training and Jinshui Liujun decoction supplementation.","authors":"Haewon Byeon","doi":"10.5498/wjp.v15.i3.101876","DOIUrl":"10.5498/wjp.v15.i3.101876","url":null,"abstract":"<p><p>This article delves into the research conducted by Liu DW <i>et al</i> on the integration of mindfulness-based stress reduction training (MSRT) and flavored Jinshui Liujun decoction (FJLD) with conventional chemotherapy (CC) in the treatment of non-small cell lung cancer. The study investigates the impact of this combined approach on immune function and emotional well-being of non-small cell lung cancer patients. Patients were divided into a control group (CG) receiving CC alone and a treatment group (TG) receiving MSRT + FJLD alongside CC. The primary outcomes were progression-free survival and overall survival, with secondary outcomes including Karnofsky performance status scores, clinical efficacy, immune function markers, and emotional state assessments. The findings underscore significant improvements in median progression-free survival (20.50 months in TG <i>vs</i> 13.10 months in CG, <i>P</i> < 0.05), Karnofsky performance status scores (60 in TG <i>vs</i> 50 in CG, <i>P</i> < 0.05), and immune cell ratios, along with reductions in negative emotions (self-rating anxiety scale and self-rating depression scale scores significantly lower in TG, <i>P</i> < 0.05) among patients receiving MSRT + FJLD in conjunction with CC. This article highlights the potential of combining traditional Chinese medicine and modern psychological interventions to enhance the efficacy of conventional cancer treatments and improve patient outcomes.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101876"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future anxiety mediates the relationship between organ donation and transplantation knowledge and health-related quality of life.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.103175
Amil Huseynov, Begum Satici
{"title":"Future anxiety mediates the relationship between organ donation and transplantation knowledge and health-related quality of life.","authors":"Amil Huseynov, Begum Satici","doi":"10.5498/wjp.v15.i3.103175","DOIUrl":"10.5498/wjp.v15.i3.103175","url":null,"abstract":"<p><strong>Background: </strong>Knowledge about organ donation and transplantation plays a crucial role in shaping individuals' health behaviors and perceptions, potentially impacting their health-related quality of life (HRQoL). Future anxiety, defined as the anticipatory worry individuals experience regarding potential negative events and outcomes in their future, may further influence these outcomes.</p><p><strong>Aim: </strong>To investigate the effect of such knowledge on HRQoL and to examine whether future anxiety mediates this relationship.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 659 participants aged 18 to 65 years. Participants completed the Organ Tissue Donation and Transplantation Knowledge Scale, the Dark Future Scale, and the European Health Interview Survey-Quality of Life 8. Correlation analyses were performed, followed by Structural Equation Modeling to test the proposed mediation model.</p><p><strong>Results: </strong>The findings indicated that greater knowledge about organ donation and transplantation was positively associated with higher HRQoL and negatively associated with future anxiety. Future anxiety was negatively correlated with HRQoL. Structural Equation Modeling analysis indicated that knowledge directly enhanced HRQoL and reduced future anxiety. Additionally, future anxiety negatively affected HRQoL, mediating the relationship between knowledge and HRQoL. The mediation effect was significant, as confirmed by bootstrapping (bootstrap coefficient = 0.068, 95%CI: 0.046-0.093).</p><p><strong>Conclusion: </strong>The study concludes that future anxiety partially mediates the positive impact of knowledge about organ donation and transplantation on HRQoL. These results suggest that increasing public knowledge in this area may reduce future anxieties and enhance quality of life.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103175"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of key brain networks and functional connectivities of successful aging: A surface-based resting-state functional magnetic resonance study.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.100456
Jiao-Jiao Sun, Li Zhang, Ru-Hong Sun, Xue-Zheng Gao, Chun-Xia Fang, Zhen-He Zhou
{"title":"Identification of key brain networks and functional connectivities of successful aging: A surface-based resting-state functional magnetic resonance study.","authors":"Jiao-Jiao Sun, Li Zhang, Ru-Hong Sun, Xue-Zheng Gao, Chun-Xia Fang, Zhen-He Zhou","doi":"10.5498/wjp.v15.i3.100456","DOIUrl":"10.5498/wjp.v15.i3.100456","url":null,"abstract":"<p><strong>Background: </strong>Successful aging (SA) refers to the ability to maintain high levels of physical, cognitive, psychological, and social engagement in old age, with high cognitive function being the key to achieving SA.</p><p><strong>Aim: </strong>To explore the potential characteristics of the brain network and functional connectivity (FC) of SA.</p><p><strong>Methods: </strong>Twenty-six SA individuals and 47 usual aging individuals were recruited from community-dwelling elderly, which were taken the magnetic resonance imaging scan and the global cognitive function assessment by Mini Mental State Examination (MMSE). The resting state-functional magnetic resonance imaging data were preprocessed by DPABISurf, and the brain functional network was conducted by DPABINet. The support vector machine model was constructed with altered functional connectivities to evaluate the identification value of SA.</p><p><strong>Results: </strong>The results found that the 6 inter-network FCs of 5 brain networks were significantly altered and related to MMSE performance. The FC of the right orbital part of the middle frontal gyrus and right angular gyrus was mostly increased and positively related to MMSE score, and the FC of the right supramarginal gyrus and right temporal pole: Middle temporal gyrus was the only one decreased and negatively related to MMSE score. All 17 significantly altered FCs of SA were taken into the support vector machine model, and the area under the curve was 0.895.</p><p><strong>Conclusion: </strong>The identification of key brain networks and FC of SA could help us better understand the brain mechanism and further explore neuroimaging biomarkers of SA.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100456"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of inflammatory markers with depression and sleep disorders accompanying the prodromal stage of Parkinson's disease.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.99901
Cheng-Guang Zhang, Yu Zhang, Ke Xu, Shun Wang, Yan Bai
{"title":"Correlation of inflammatory markers with depression and sleep disorders accompanying the prodromal stage of Parkinson's disease.","authors":"Cheng-Guang Zhang, Yu Zhang, Ke Xu, Shun Wang, Yan Bai","doi":"10.5498/wjp.v15.i3.99901","DOIUrl":"10.5498/wjp.v15.i3.99901","url":null,"abstract":"<p><p>Parkinson's disease (PD) is a common neurodegenerative disorder with increasing incidence and disability rates globally, placing a heavy burden on patients and their families. In the prodromal phase of PD, nonmotor symptoms, particularly depression and sleep disorders, are frequent, with profound effects on disease progression and patient quality of life. Emerging research highlights the critical role of inflammatory markers-including interleukins and tumor necrosis factor-in the pathogenesis of prodromal PD. These inflammatory mediators participate in neurodegenerative processes and may induce or exacerbate depressive symptoms and sleep disorders by disrupting the function of the hypothalamic-pituitary-adrenal axis and affecting neurotransmitter, including serotonin, metabolism. Understanding their correlations with nonmotor symptoms in prodromal PD remains incomplete, limiting our ability to develop targeted interventions. This comprehensive review aims to investigate the specific correlations between inflammatory markers and nonmotor symptoms-particularly depression and sleep disorders-in prodromal PD. The findings could have important practical applications, potentially leading to the development of new diagnostic tools and therapeutic strategies for managing PD. By identifying and understanding these correlations, healthcare providers may better predict disease progression and implement more effective treatments for nonmotor symptoms in PD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99901"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Voxel-based alterations in spontaneous brain activity among very-late-onset schizophrenia-like psychosis: A preliminary resting-state functional magnetic resonance imaging study.
IF 3.9 4区 医学
World Journal of Psychiatry Pub Date : 2025-03-19 DOI: 10.5498/wjp.v15.i3.101494
Dan-Ting Yang, Ping Ji, Jiao-Jiao Sun, Yan-Sha Gan, Shuai-Yi Guo, Zhen-He Zhou, Xue-Zheng Gao
{"title":"Voxel-based alterations in spontaneous brain activity among very-late-onset schizophrenia-like psychosis: A preliminary resting-state functional magnetic resonance imaging study.","authors":"Dan-Ting Yang, Ping Ji, Jiao-Jiao Sun, Yan-Sha Gan, Shuai-Yi Guo, Zhen-He Zhou, Xue-Zheng Gao","doi":"10.5498/wjp.v15.i3.101494","DOIUrl":"10.5498/wjp.v15.i3.101494","url":null,"abstract":"<p><strong>Background: </strong>Very late-onset schizophrenia-like psychosis (VLOSLP) is a subtype of schizophrenia spectrum disorders in which individuals experience psychotic symptoms for the first time after the age of 60. The incidence of VLOSLP shows a linear relationship with increasing age. However, no studies have reported alterations in spontaneous brain activity among VLOSLP patients and their correlation with cognitive function and clinical symptoms.</p><p><strong>Aim: </strong>To explore VLOSLP brain activity and correlations with cognitive function and clinical symptoms using resting-state functional magnetic resonance imaging.</p><p><strong>Methods: </strong>This study included 33 VLOSLP patients and 34 healthy controls. The cognitive assessment utilized the Mini Mental State Examination, Montreal Cognitive Assessment, and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Clinical characteristic acquisition was performed <i>via</i> the Positive and Negative Syndrome Scale (PANSS). All participants were scanned <i>via</i> resting-state functional magnetic resonance imaging, and the data were processed using amplitude of low-frequency fluctuations (ALFF), fractional ALFF (fALFF), regional homogeneity, and voxel-mirrored homotopic connectivity (VMHC).</p><p><strong>Results: </strong>The VLOSLP group presented decreased ALFF values in the left cuneus, right precuneus, right precentral gyrus, and left paracentral lobule; increased fALFF values in the left caudate nucleus; decreased fALFF values in the right calcarine fissure and surrounding cortex (CAL) and right precuneus; increased regional homogeneity values in the right putamen; and decreased VMHC values in the bilateral CAL, bilateral superior temporal gyrus, and bilateral cuneus. In the VLOSLP group, ALFF values in the right precuneus were negatively correlated with Mini Mental State Examination score and PANSS positive subscale score, and VMHC values in the bilateral CAL were negatively correlated with the RBANS total score, RBANS delayed memory score, and PANSS positive subscale score.</p><p><strong>Conclusion: </strong>The changes of brain activity in VLOSLP are concentrated in the right precuneus and bilateral CAL regions, which may be associated with cognitive impairment and clinically positive symptoms.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101494"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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