World Journal of Psychiatry最新文献

{"title":"Digital cognitive behavioral therapy as a novel treatment for insomnia.","authors":"Xu-Tong Tian, Yao Meng, Ru-Lan Wang, Rong Tan, Mei-Shan Liu, Wen Xu, Shuai Cui, Yun-Xiang Tang, Meng-Yang He, Wen-Peng Cai","doi":"10.5498/wjp.v15.i4.104042","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.104042","url":null,"abstract":"<p><strong>Background: </strong>As a substitute for traditional drug therapy, digital cognitive-behavioral therapy positively impacts the regulation of brain function, which can improve insomnia. However, there is currently a paucity of studies on digital cognitive behavioral therapy as a treatment for insomnia.</p><p><strong>Aim: </strong>To assess digital cognitive behavioral therapy for insomnia regarding its positive impact on brain function.</p><p><strong>Methods: </strong>Participants were randomly assigned to either a go/no-go group or a dot-probe group. The primary outcome was quality of sleep as assessed by the actigraphy sleep monitoring bracelet, Pittsburgh sleep quality index (PSQI), insomnia severity index (ISI), and depression anxiety and stress scale (DASS-21).</p><p><strong>Results: </strong>Eighty patients were included in the analysis (go/no-go group: <i>n</i> = 40; dot-probe group: <i>n</i> = 40). We combined the total scale scores of the two groups before and after the intervention in the analysis of covariance. Our study explored whether insomnia symptoms in both groups can be improved by using digital cognitive behavioral therapy instead of trying to compare the two trials; therefore, only one <i>P</i> value is listed. In both groups, we found a short-term time effect on insomnia symptom severity (PSQI: <i>P</i> < 0.001, <i>η</i> ² = 0.336; ISI: <i>P</i> < 0.001, <i>η</i> ² = 0.667; DASS-depression: <i>P</i> < 0.001, <i>η</i> ² = 0.582; DASS-anxiety: <i>P</i> < 0.001, <i>η</i> ² = 0.337; DASS-stress: <i>P</i> < 0.001, <i>η</i> ² = 0.443) and some effect on sleep efficiency (but it was not significant, <i>P</i> = 0.585, <i>η</i> ² = 0.004).</p><p><strong>Conclusion: </strong>Go/no-go task training of inhibitory function had a short-term positive effect on sleep efficiency, whereas dot-probe task training had a positive short-term effect on emotion regulation.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"104042"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From health literacy to organ donation and transplantation awareness: The path through self-control.","authors":"Amil Huseynov, Begum Satici","doi":"10.5498/wjp.v15.i4.104859","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.104859","url":null,"abstract":"<p><strong>Background: </strong>Organ donation and transplantation are vital for saving lives, yet awareness remains limited. Health literacy, the ability to understand and use health information, and self-control, which influences decision-making, are crucial factors in promoting awareness. Understanding their relationship can guide efforts to increase participation in organ donation.</p><p><strong>Aim: </strong>To investigate the effect of health literacy on organ donation and transplantation awareness, with self-control acting as a mediator, and to emphasize its importance.</p><p><strong>Methods: </strong>The study comprised 345 adults recruited from five different cities in Türkiye. The sample included 208 women (60.29%) and 137 men (39.71%). The age range of the sample group varies between 18 and 49 (median age = 24.13; SD = 8.81). Self-report data were collected including psychometric measures assessing organ donation and transplantation awareness, health literacy, and self-control. Reliability analysis, descriptive statistics, correlational analysis, and mediational analysis of the data were carried.</p><p><strong>Results: </strong>The analysis showed that health literacy was positively correlated with organ donation and transplantation awareness (<i>r</i> = 0.340) and self-control (<i>r</i> = 0.376). Self-control was positively related to organ donation and transplantation awareness (<i>r</i> = 0.531). Mediating analysis supported a mediation model where health literacy was found to influence organ donation and transplantation awareness <i>via</i> self-control (bootstrap = 0.158, 95% confidence interval = 0.105-0.215).</p><p><strong>Conclusion: </strong>The results indicate that self-control mediates the positive relationship between health literacy and organ donation and transplantation awareness. Enhancing individuals' health literacy may therefore increase awareness of organ donation and transplantation through improvements in self-control.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"104859"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive bibliometric analysis of transcranial magnetic stimulation-based depression treatment from 2003 to 2022: Research hotspots and trends.","authors":"Zheng-Yu Li, Yu-Wei Zhang, Hao-Ran Yang, Yu-Qing Ren, Hong-Jin Wu, Meng-Yun Zhang, Song Zhang, Ying-Fu Jiao, Wei-Feng Yu, Jie Xiao, Po Gao, Heng Yang","doi":"10.5498/wjp.v15.i4.104600","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.104600","url":null,"abstract":"<p><strong>Background: </strong>Depression has become a global public health problem. In recent years, transcranial magnetic stimulation (TMS) has gained considerable attention as a non-invasive treatment for depression.</p><p><strong>Aim: </strong>To investigate the research hotspots and trends in the field of TMS-based depression treatment from a bibliometric perspective.</p><p><strong>Methods: </strong>Using the Web of Science Core Collection, articles published between 2003 and 2022 on TMS-based depression treatment were retrieved from the science citation index expanded. The publication trends and research hotspots were analyzed using VOSviewer, CiteSpace, and the bibliometric online analysis platform. Regression analysis was performed using Microsoft Excel 2021 to predict publication growth trends.</p><p><strong>Results: </strong>We identified a total of 702 articles on TMS-based depression treatment with a predominance of clinical studies. Analysis of collaborative networks showed that the United States, the University of Toronto, and Daskalakis ZJ were identified as the most impactful country, institution, and researcher, respectively. In keyword burst analysis, it was found that theta burst stimulation (TBS), functional connectivity, and frequency were the most recent research hotspots.</p><p><strong>Conclusion: </strong>TMS provides a novel therapeutic option for patients with treatment-resistant depression. Neuroimaging technology enables more precise TMS treatment, while the novel TMS modality, TBS, enhances both therapeutic efficacy and patient experience in TMS-based depression treatment. The integration of neuroimaging techniques with TBS represents a promising research direction for advancing TMS-based depression treatment. This study presents systematic information and recommendations to guide future research on TMS-based depression treatment.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"104600"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motoric cognitive risk syndrome: A review of fall risk assessment and management strategies.","authors":"Hao Peng, Na Yao, Yan-Ping Song, Li Huang, Hong-Bo Chen, Yang Jiang, Qi-Gang Chen","doi":"10.5498/wjp.v15.i4.101800","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.101800","url":null,"abstract":"<p><p>The aging global population is driving an increase in dementia, making the early identification of at-risk individuals crucial. Studies have shown that elderly people often exhibit a slowing gait before dementia diagnosis, which is linked to cognitive decline and predicts dementia risk. With 30% of those over 65 years of age experiencing falls annually, managing fall risk is essential. Motoric cognitive risk syndrome (MCR), characterized by subjective memory impairment and slow gait, is a pre-dementia condition that can identify high-risk individuals without extensive evaluation. The prevalence of MCR varies globally and is associated with an increased risk of falls, disability, and death. Early screening and intervention for MCR can delay dementia and improve fall regulation, offering a new perspective on elderly health management. This review synthesizes the current understanding of MCR-related falls, evaluates risk assessment methods, and discusses health strategies to provide a theoretical basis for fall prevention in community-dwelling older adults.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"101800"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of anxiety and depression and influencing factors in non-Hodgkin's lymphoma of the nasal cavity and paranasal sinus.","authors":"Xu-Dong Gao, Jin Zhang, An Li, Yu Ding, Bo Zhao, Lan Li","doi":"10.5498/wjp.v15.i4.99346","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.99346","url":null,"abstract":"<p><strong>Background: </strong>Natural killer (NK)/T-cell non-Hodgkin's lymphoma (NHL) in the nasal cavities and paranasal sinuses accounts for approximately 10% of all lymphomas, and the occurrence of nasal NHL is related to Epstein-Barr virus infection.</p><p><strong>Aim: </strong>To explore the anxiety and depression status of patients with NK/T-cell NHL in the nasal cavities and paranasal sinuses and analyzes the relevant influencing factors.</p><p><strong>Methods: </strong>A retrospective analysis was performed, which included 30 patients with primary nasal NK/T-cell NHL treated in Shaanxi Provincial People's Hospital from January 2017 to January 2023. An additional 50 healthy volunteers were selected as the control group. Both groups were assessed using the self-rating anxiety scale (SAS) and Self-rating (SDS). SDS and SAS scores of patients with NHL at different disease stages were analyzed, and they were further grouped into negative emotion (NE) (<i>n</i> = 19) and non-NE (<i>n</i> = 11) groups based on their depression and anxiety. Factors affecting the occurrence of NEs in patients with NHL were analyzed using univariate and multivariate logistic regression models.</p><p><strong>Results: </strong>Patients with NHL exhibited higher SDS and SAS scores than healthy controls. Moreover, patients with NHL at stages III and IV had higher SDS and SAS scores than those in stage I. Among the 30 patients, there were 13 patients with depression (43.3%), 16 patients with anxiety (53.3%), and 10 patients with both anxiety and depression (33.3%). Univariate analysis identified a higher proportion of people in the NE group with stage III-IV NHL, an educational level ≤ high school, and a monthly household income < 5000 yuan compared with the non-NE group. Multiple logistic regression analysis further revealed that stage III-IV was a risk factor for NEs in patients with NHL.</p><p><strong>Conclusion: </strong>The stage of NK/T-cell NHL in nasal cavities and paranasal sinuses is closely related to patient anxiety and depression. The higher the staging, the greater the incidence of anxiety and depression.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"99346"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vulnerable brain regions in adolescent attention deficit hyperactivity disorder: An activation likelihood estimation meta-analysis.","authors":"Yan-Ping Shu, Qin Zhang, Da Li, Jiao-Ying Liu, Xiao-Ming Wang, Qiang He, Yong-Zhe Hou","doi":"10.5498/wjp.v15.i4.102215","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.102215","url":null,"abstract":"<p><strong>Background: </strong>Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder in adolescents characterized by inattention, hyperactivity, and impulsivity, which impact cognitive, behavioral, and emotional functioning. Resting-state functional magnetic resonance imaging (rs-fMRI) provides critical insights into the functional architecture of the brain in ADHD. Despite extensive research, specific brain regions consistently affected in ADHD patients during these formative years have not been comprehensively delineated.</p><p><strong>Aim: </strong>To identify consistent vulnerable brain regions in adolescent ADHD patients using rs-fMRI and activation likelihood estimation (ALE) meta-analysis.</p><p><strong>Methods: </strong>We conducted a comprehensive literature search up to August 31, 2024, to identify studies investigating functional brain alterations in adolescents with ADHD. We utilized regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF), dynamic ALFF (dALFF) and fractional ALFF (fALFF) analyses. We compared the regions of aberrant spontaneous neural activity in adolescents with ADHD with those in healthy controls (HCs) using ALE.</p><p><strong>Results: </strong>Fifteen studies (468 adolescent ADHD patients and 466 HCs) were included. Combining the ReHo and ALFF/fALFF/dALFF data, the results revealed increased activity in the right lingual gyrus [LING, Brodmann Area (BA) 18], left LING (BA 18), and right cuneus (CUN, BA 23) in adolescent ADHD patients compared with HCs (voxel size: 592-32 mm³, <i>P</i> < 0.05). Decreased activity was observed in the left medial frontal gyrus (MFG, BA 9) and left precuneus (PCUN, BA 31) in adolescent ADHD patients compared with HCs (voxel size: 960-456 mm³, <i>P</i> < 0.05). Jackknife sensitivity analyses demonstrated robust reproducibility in 11 of the 13 tests for the right LING, left LING, and right CUN and in 11 of the 14 tests for the left MFG and left PCUN.</p><p><strong>Conclusion: </strong>We identified specific brain regions with both increased and decreased activity in adolescent ADHD patients, enhancing our understanding of the neural alterations that occur during this pivotal stage of development.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"102215"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-compassion, automatic thoughts, and mental pain in depression: Mediating effects and clinical implications.","authors":"Li-Na Ren, Ji-Song Pang, Qiao-Na Jiang, Xiao-Fei Zhang, Lu-Lu Li, Jing Wang, Jian-Gong Li, Yan-Yan Ma, Wei Jia","doi":"10.5498/wjp.v15.i4.101105","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.101105","url":null,"abstract":"<p><strong>Background: </strong>Depression is a leading global health concern with high suicide rates and recurrence. Cognitive models suggest that mental pain and automatic thoughts are central to depression's impact. The hypothesis is that self-compassion will be negatively associated with mental pain, mediated by automatic thoughts.</p><p><strong>Aim: </strong>To determine the mediating role of automatic thoughts in the relationship between self-compassion and mental pain in individuals with depression.</p><p><strong>Methods: </strong>This cross-sectional study included 389 inpatients with depression from Tianjin Anding Hospital. Participants completed the Self-Compassion Scale-Chinese Version (SCS-C), Automatic Thought Questionnaire (ATQ), and Orbach & Mikulincer Mental Pain Scale-Chinese Version (OMMP). Data were analyzed using Pearson correlations, multiple linear regressions, and mediation analysis.</p><p><strong>Results: </strong>The SCS-C total score was 68.95 ± 14.89, ATQ was 87.02 ± 28.91, and OMMP was 129.01 ± 36.74. Correlation analysis showed mental pain was positively associated with automatic thoughts (<i>r</i> = 0.802, <i>P</i> < 0.001) and negatively with self-compassion (<i>r</i> = -0.636, <i>P</i> < 0.001). Regression analysis indicated automatic thoughts (β = 0.623, <i>P</i> < 0.001) and self-compassion (β = -0.301, <i>P</i> < 0.001) significantly predicted mental pain. Mediation analysis confirmed automatic thoughts partially mediated the relationship between self-compassion and mental pain (ab = -0.269, 95%CI: -0.363 to -0.212).</p><p><strong>Conclusion: </strong>Self-compassion is inversely related to mental pain in depression, with automatic thoughts playing a mediating role. These findings suggest potential therapeutic targets for alleviating mental pain in depressed patients.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"101105"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of influencing factors of psychological resilience in patients with traumatic fractures and its effect on posttraumatic growth.","authors":"Dao-Zhen Chen, Kun-Feng Chen, Ji-Sheng Xu, Kun Gao","doi":"10.5498/wjp.v15.i4.100819","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.100819","url":null,"abstract":"<p><strong>Background: </strong>Traumatic fractures are mainly caused by various exogenous traumatic events, which not only damage patients' physical health but also affect their psychological state and aggravate stress responses.</p><p><strong>Aim: </strong>To analyze the influencing factors of psychological resilience of patients with traumatic fractures and the effect of psychological resilience on posttraumatic growth (PTG).</p><p><strong>Methods: </strong>This study included 188 patients with traumatic fractures admitted to the First People's Hospital of Shangqiu from November 2022 to November 2023. The participants were categorized based on the patient's psychological resilience assessed by the Connor-Davidson Resilience Scale (CD-RISC) into the better resilience group (CD-RISC score ≥ 60 points, <i>n</i> = 80) and the poor resilience group (CD-RISC score < 60 points, <i>n</i> = 108). Patients' sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI). The identification of the influencing factors of psychological resilience in patients with traumatic fractures was realized by binary Logistic regression (with factors such as sex, age, injury cause, trauma severity, fracture site, personality, and PSQI included for analysis). The determination of the PTG status of all participants used the Chinese version of the Posttraumatic Growth Inventory (C-PTGI). Furthermore, a Spearman correlation analysis was conducted to analyze the association between psychological resilience and PTG.</p><p><strong>Results: </strong>The psychological resilience of patients with traumatic fractures was related to age, sex, trauma severity, and personality. The better resilience group demonstrated statistically lower PSQI scores than the poor resilience group (<i>P</i> < 0.05). The Logistic regression analysis revealed sex, age, trauma severity, personality, and sleep quality as influencing factors of CD-RISC scores in patients with traumatic fractures (all <i>P</i> < 0.05). The score of each C-PTGI dimension and the total score (relating to others, new possibilities, personal strength, spiritual change, and appreciation of life) were higher in the better resilience group than in the poor resilience group (all <i>P</i> < 0.05). Spearman correlation analysis indicated a positive association of the CD-RISC score in patients with traumatic fractures with the scores of all dimensions of C-PTGI and the total C-PTGI score (all <i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The factors influencing the psychological resilience of patients with traumatic fractures include age, sex, trauma severity, personality, and sleep quality, and psychological resilience is closely associated with PTG.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"100819"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Media consumption patterns and depressive and anxiety symptoms in the Chinese general population during the COVID-19 outbreak.","authors":"Rui-Yao Wu, Lin-Feng Ge, Bao-Liang Zhong","doi":"10.5498/wjp.v15.i4.104625","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.104625","url":null,"abstract":"<p><strong>Background: </strong>Examining patterns of media consumption and their associations with mental health outcomes in the general population during the coronavirus disease 2019 (COVID-19) pandemic has implications for public mental health in future pandemics.</p><p><strong>Aim: </strong>To investigate patterns of media consumption and their associations with depressive and anxiety symptoms among adults affected by the COVID-19 pandemic.</p><p><strong>Methods: </strong>A total of 8473 adults were recruited through snowball sampling for an online cross-sectional survey. The participants were asked to report the three media sources from which they most frequently acquired knowledge about COVID-19 from a checklist of nine media sources. Depression and anxiety were assessed with the Patient Health Questionnaire and the Generalized Anxiety Disorder Scale, respectively. A two-step cluster analysis was performed to identify distinct clusters of consumption of media sources.</p><p><strong>Results: </strong>Seven clusters were identified. The lowest prevalence of depression and anxiety (29.1% and 22.8%, respectively) was observed in cluster one, which was labeled \"television and news portals and clients, minimal social media\". The highest prevalence of depression (43.1%) was observed in cluster three, labeled \"WeChat, MicroBlog, and news portals, minimal traditional media\". The greatest prevalence of anxiety (35.8%) was observed in cluster seven, which was labeled \"news clients and WeChat, no newspaper, radio, or news portals\". Relative to cluster one, a significantly elevated risk of depression and anxiety was found in clusters three, six (labeled \"news portals and clients, WeChat, no newspaper and radio\") and seven (adjusted odds ratio = 1.28-1.46, <i>P</i> ≤ 0.011). Multiple logistic regression analyses revealed that the risk of COVID-19 infection and knowledge about COVID-19 partially explained the variations in the prevalence of depression and anxiety across the seven clusters.</p><p><strong>Conclusion: </strong>Communication policies should be designed to channel crucial pandemic-related information more effectively through traditional and digital media sources. Encouraging the use of these media and implementing regulatory policies to reduce misinformation and rumors on social media, may be effective in mitigating the risk of depression and anxiety among populations affected by the pandemic.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"104625"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between inflammatory factors, lactic acid levels, acute skin failure, bad mood, and sleep quality.","authors":"Yu-Fei Liu, Wen Cong, Chang-Ming Zhou, Yang Yu, Xin-Jie Zhang","doi":"10.5498/wjp.v15.i4.102763","DOIUrl":"https://doi.org/10.5498/wjp.v15.i4.102763","url":null,"abstract":"<p><strong>Background: </strong>The central link between septic shock and acute skin failure (ASF) is the inflammatory response, which occurs throughout disease progression and can lead to systemic inflammatory response syndrome. Patients often experience bad moods, sleep disorders, and other health issues. Despite recognizing these factors, no studies have examined the correlation between inflammatory factors, lactic acid levels, ASF, mood disturbances, and sleep quality in critically ill patients. We hypothesize that higher levels of inflammatory factors and lactic acid are associated with more severe ASF and poorer mood and sleep quality, which may inform clinical treatment for septic shock and ASF.</p><p><strong>Aim: </strong>To explore the relationship between inflammatory factors, lactic acid levels, the severity of ASF, bad mood, and sleep quality.</p><p><strong>Methods: </strong>The retrospective study included 150 patients with septic shock from the Second Hospital of Dalian Medical University, categorized into ASF (<i>n</i> = 35) or non-ASF groups (<i>n</i> = 115). We compared the peripheral blood inflammatory factors, including tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), interleukin-6 (IL-6), lactic acid levels, skin mottling score (SMS), modified early warning score (MEWS), self-rating depression scale (SDS), self-rating anxiety scale (SAS), and Pittsburgh sleep quality index (PSQI) scores. Pearson correlation analysis assessed relationships among these variables.</p><p><strong>Results: </strong>The ASF group had significantly higher levels of CRP (19.60 ± 4.10 <i>vs</i> 15.30 ± 2.96 mg/mL), IL-6 (298.65 ± 48.65 <i>vs</i> 268.66 ± 33.66 pg/L), procalcitonin, lactic acid (8.42 ± 2.32 <i>vs</i> 5.70 ± 1.27 mmol/L), SMS [0 (0, 1) <i>vs</i> 3 (2, 3)], MEWS (9.34 ± 1.92 <i>vs</i> 6.48 ± 1.96), SAS (61.63 ± 12.03 <i>vs</i> 53.71 ± 12.48), SDS (60.17 ± 12.64 <i>vs</i> 52.27 ± 12.64), and PSQI scores (14.23 ± 3.94 <i>vs</i> 8.69 ± 2.46) compared with the non-ASF group (all <i>P</i> < 0.001). Pearson correlation analysis revealed that IL-6, CRP, TNF-α, and lactic acid were positively correlated with SMS, MEWS, SAS, SDS, and PSQI scores (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Peripheral blood levels of IL-6, CRP, TNF-α, and lactic acid correlate positively with SMS, MEWS, SAS, SDS, and PSQI in critically ill patients with ASF.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 4","pages":"102763"},"PeriodicalIF":3.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}