World Journal of Psychiatry最新文献

{"title":"College students' depression and body image: Unraveling the Link.","authors":"Zhao-Jun Cheng, Hu Tao, Hua-Guo Huan, Chun-Mei Wu, Qi Wang, Ming Hao","doi":"10.5498/wjp.v15.i9.109611","DOIUrl":"10.5498/wjp.v15.i9.109611","url":null,"abstract":"<p><strong>Background: </strong>With the increasing global incidence of mental illness, depression has become a serious problem among college students.</p><p><strong>Aim: </strong>To investigate the relationship between depression and its correlates in Chinese adolescents and to identify diagnostic predictors of depression, examine the effects of binge eating, physical activity, and body dissatisfaction on depression among college students and to determine a diagnostic cutoff value for depression based on body dissatisfaction.</p><p><strong>Methods: </strong>We conducted a cross-sectional survey of 1286 college students in South China. Physical activity level, depressive symptoms, and binge eating behavior were assessed using the Physical Activity Scale-3, Zung Self-Rating Depression Scale, and Dutch Eating Behavior Questionnaire, respectively. The absolute difference between actual body mass index (BMI) and ideal BMI was used to indicate the level of body dissatisfaction. Structural equation modeling (SEM) and receiver operating characteristic (ROC) curve analysis were used to examine the relationships between these variables and depression.</p><p><strong>Results: </strong>The findings showed that female college students reported higher levels of depression. Physical activity, body dissatisfaction, and binge eating behavior were significantly associated with depression. SEM revealed that body dissatisfaction played a mediating role. A body dissatisfaction score of 1.73 was identified as the diagnostic cutoff value for predicting depression, with an area under the ROC curve of 70.0%, providing a basis for targeted interventions.</p><p><strong>Conclusion: </strong>This study demonstrated a significant positive correlation between body dissatisfaction and depression. Low levels of physical activity and binge eating behaviors were found to heighten the risk of depression. Therefore, promoting physical activity and healthy eating habits among adolescents is essential. Additionally, the identification of a diagnostic threshold for body dissatisfaction represents a novel finding with important implications for early screening. Future longitudinal studies are recommended to further refine this diagnostic criterion.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"109611"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness-based stress reduction and mental health in department of emergency nurses: A narrative review.","authors":"Rong-Rong Zhou, Ling-Long Chen, Le-Dan Lin","doi":"10.5498/wjp.v15.i9.107630","DOIUrl":"10.5498/wjp.v15.i9.107630","url":null,"abstract":"<p><p>Emergency department nurses face severe occupational stress leading to anxiety, depression, and burnout, which significantly impair their well-being and patient-care quality. This narrative review examined the role of mindfulness-based stress reduction (MBSR) in addressing these challenges. Rooted in nonjudgmental present-moment awareness, MBSR enhances emotional regulation and reduces psychological distress by fostering adaptive coping strategies. Studies have demonstrated its efficacy in lowering anxiety, depressive symptoms, and emotional exhaustion, while improving workplace well-being, empathy, and job satisfaction. Mechanistically, MBSR improves interoceptive awareness and autonomic balance, as evidenced by physiological markers such as heart rate variability. However, gaps remain in long-term efficacy assessments, personalized interventions, and integration with multidisciplinary approaches. Future research should prioritize tailored biomarker-driven programs, longitudinal studies, and scalable implementation strategies in high-stress clinical settings. This review underscores MBSR's potential as a sustainable, evidence-based tool to enhance emergency department nurses' mental health and professional performance, advocating for broader adoption and further refinement of its practical applications.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"107630"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic algorithm for clozapine-induced myocarditis: A systematic review.","authors":"Yassir Mahgoub, Rawan Alhau, Yumna Magzoub, Aya Ali, Eptihal Nour, Mustafa E E Saeed, Sameera G M Mohamed, Ahmed O S Hassan, Omaima Ali","doi":"10.5498/wjp.v15.i9.108525","DOIUrl":"10.5498/wjp.v15.i9.108525","url":null,"abstract":"<p><strong>Background: </strong>Clozapine, the gold standard for resistant schizophrenia, is underused due to risks like clozapine-induced myocarditis (CIM). Non-specific biomarkers and inconsistent imaging, and the significant overlap with clozapine-induced pneumonia (CIP) lead to misdiagnosis and premature discontinuation.</p><p><strong>Aim: </strong>To develop a diagnostic algorithm for CIM to enhance accuracy, differentiate from CIP, and guide safe clozapine rechallenge.</p><p><strong>Methods: </strong>A systematic review of 119 PubMed studies (published between 1990 and April 2025) was conducted in accordance with PRISMA guidelines. The review analyzed CIM diagnosis and rechallenge outcomes, with a focus on biomarkers, imaging, and collaboration with cardiology.</p><p><strong>Results: </strong>CIM diagnosis relies on troponin and C-reactive protein; electrocardiography and echocardiography are inconsistently applied, and cardiac magnetic resonance imaging (CMR) is underused. Rechallenge was successful in 64.7% to 68.9% of 136 cases, with 2.9% resulting in fatal outcomes. Up to 65% of presumed CIM cases lack confirmation. A proposed protocol integrates chest computed tomography to exclude pneumonia and CMR for CIM confirmation, with echocardiography as an alternative.</p><p><strong>Conclusion: </strong>A protocol involving multidisciplinary collaboration among computed tomography, CMR, and cardiology improves CIM diagnosis. Slow titration prevents CIM; adjust the dose for CIP and discontinue for confirmed CIM.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"108525"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression.","authors":"Guo-Guang Zhao, Jing Zhao, Yan Kong, Ya-Ping Pang, Xiao-Nan Zheng, Yi-Wei Zhang","doi":"10.5498/wjp.v15.i9.109458","DOIUrl":"10.5498/wjp.v15.i9.109458","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Treatment-resistant depression (TRD) has a poor response to clinical treatment. Patients with TRD do not respond adequately to standard antidepressants. Even after receiving a full dose and sufficient duration of combined antidepressant therapy, significant improvement is still difficult to achieve. At present, electroconvulsive therapy (ECT) remains a clinically effective method for treating refractory depression. A good anesthesia regimen can enhance its clinical efficacy. Actively exploring high-quality anesthesia regimens has become a current research hotspot.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To explore the effect of esketamine and etomidate anesthesia on the clinical efficacy of ECT for TRD.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 120 patients with TRD, treated at the Department of Psychiatry, The Second Affiliated Hospital of Shandong First Medical University, China between April 2020 and April 2024, were selected for the study. The patients were allocated at random into two groups using a random number table: The combination and control groups, with 60 patients in each group. Both groups underwent ECT; the combination group received esketamine and etomidate anesthesia, while the control group received etomidate anesthesia. The following parameters were compared between the two groups: Heart rate (HR); mean arterial pressure (MAP); peripheral capillary oxygen saturation (SpO&lt;sub&gt;2&lt;/sub&gt;); initial and final threshold charges; and serum brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), 5-hydroxytryptamine (5-HT), and interleukin-4 (IL-4) levels. Neurological functions, basic executive function scores, and adverse reactions were compared during the treatment process.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;During treatment, the maximum and minimum HR and MAP values in the combination group were markedly lower than those in the control group (&lt;i&gt;P&lt;/i&gt; &lt; 0.05), whereas there was no significant difference in SpO&lt;sub&gt;2&lt;/sub&gt; between the two groups (&lt;i&gt;P&lt;/i&gt; &gt; 0.05). During the treatment, there were no significant differences in the initial threshold charge and average duration of seizures during ECT between the two groups (&lt;i&gt;P&lt;/i&gt; &gt; 0.05). However, the final threshold charge and total charge in the combination group were considerably lower than those in the control group (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). After treatment, the BDNF, NGF, 5-HT, and IL-4 levels were evidently higher in the combination group than in the control group (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). During treatment, as the number of ECT sessions increased, both BRNAS and Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB) scores increased, whereas Hamilton Depression Rating Scale (HAMD)-24 scores decreased in both groups. Starting from the third treatment session, the BRNAS and MCCB scores in the combination group were higher than in the control group, whereas the Hamilton Depression Scale-24 score was lower in the c","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"109458"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of RNA-binding proteins in exercise-induced mRNA regulation: Unveiling biomarkers and therapeutic targets for schizophrenia.","authors":"Yao Lu, Jian-Da Kong, Lu-Nan Zhao","doi":"10.5498/wjp.v15.i9.107498","DOIUrl":"10.5498/wjp.v15.i9.107498","url":null,"abstract":"<p><p>This article summarizes recent advances in the understanding of RNA-binding proteins (RBPs), with a focus on their roles in exercise-induced mRNA regulation and their implications for schizophrenia (SZ). RBPs are critical regulators of mRNA stability, splicing, transport, translation, and degradation, directly influencing gene expression through sequence- and structure-specific binding. In the nervous system, RBPs sustain synaptic plasticity, neural development, and neuronal homeostasis. Emerging evidence shows that exercise modulates the expression and activity of RBPs, thereby influencing mRNA translation and neurotransmitter signaling, which may underlie its beneficial effects on brain function. Dysregulation of specific RBPs has been identified in SZ, implicating them in disrupted synaptic transmission, impaired plasticity, and neuroinflammation. RBPs involved in memory and emotional regulation show marked dysfunction in SZ patients. Some RBPs have been proposed as potential biomarkers for early diagnosis and treatment monitoring. Moreover, therapeutic modulation of RBPs, through pharmacological or behavioral interventions such as exercise, may restore neuronal function by targeting post-transcriptional gene regulation. Exercise, as a non-invasive modulator of RBP expression, holds promise as an adjunctive strategy in SZ treatment, particularly in early stages. Further research into RBP-mediated pathways may offer novel insights into SZ pathophysiology and inform the development of targeted interventions.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"107498"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of phakic intraocular lens implantation on anxiety and depression in patients with high myopia.","authors":"Xiao-Hua Chen, Xiang-Jun Dai","doi":"10.5498/wjp.v15.i9.107924","DOIUrl":"10.5498/wjp.v15.i9.107924","url":null,"abstract":"<p><strong>Background: </strong>Phakic intraocular lens (IOL) implantation is a common treatment for high myopia. However, pre- and postoperative psychological changes, particularly anxiety and depression, are noteworthy concerns. Multiple studies have indicated a close relationship between ophthalmic diseases, including high myopia, glaucoma, anxiety, and depression.</p><p><strong>Aim: </strong>To evaluate the impact of phakic IOL implantation on anxiety and depression in patients with high myopia.</p><p><strong>Methods: </strong>Data from 136 patients with high myopia, who underwent phakic IOL implantation at the authors' hospital between June 2024 and December 2024, were retrospectively analyzed. Clinical data were collected from the hospital's electronic medical records system. Preoperative and one-month postoperative data were compared. Anxiety, depression, sleep quality, and quality of life were evaluated using the Hamilton anxiety scale, Hamilton depression scale, Pittsburgh Sleep Quality Index, and 36-item Short Form Health Survey, respectively.</p><p><strong>Results: </strong>Of 136 patients, 67.65% (<i>n</i> = 92) were female and 32.35% (<i>n</i> = 44) were male, with a mean ± SD age of 28.02 ± 5.72 years. The mean uncorrected visual acuity before and 1 month after treatment was 1.83 ± 0.24 log minimum angle of resolution (MAR) and 0.03 ± 0.07 log MAR, respectively. The mean best corrected visual acuity before and 1 month after treatment was 0.04 ± 0.07 log MAR and 0.01 ± 0.02 log MAR, respectively. All differences were statistically significant (<i>P</i> < 0.05). Compared with pretreatment, Hamilton anxiety scale and Hamilton depression scale scores significantly decreased 1 month post-treatment (<i>P</i> < 0.05). Furthermore, the Pittsburgh Sleep Quality Index score was significantly lower after than that before treatment (<i>P</i> < 0.05). The 36-item Short Form Health Survey quality of life score significantly improved after treatment (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Phakic IOL implantation significantly reduces anxiety and depression and improves sleep quality and quality of life in patients with high myopia. This study provides new concepts for treating high myopia.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"107924"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of comprehensive psychological cognitive nursing on the quality of life of patients with chronic pain and depression.","authors":"Yan Cheng, Jv-Ming Mao, Ying Zhang","doi":"10.5498/wjp.v15.i9.107534","DOIUrl":"10.5498/wjp.v15.i9.107534","url":null,"abstract":"<p><strong>Background: </strong>Chronic pain and depression often coexist, severely affecting quality of life. Traditional treatments address these conditions separately, but comprehensive psychological cognitive nursing offers a holistic approach. By combining cognitive-behavioral strategies and psychological support, it helps improve coping mechanisms, reduce distress, and enhance overall well-being in affected patients.</p><p><strong>Aim: </strong>To investigate the impact of comprehensive psychological cognitive nursing on the patients with chronic pain and depression.</p><p><strong>Methods: </strong>From October 2022 to October 2024, 171 patients with chronic pain and depression admitted to our hospital were randomly divided into two groups, with 85 patients in the control group and 86 patients in the observation group. The general data from both groups were compared. The control group received standard treatment. The observation group provided full psychological cognitive care in the same way as the control group did. The two groups of patients' psychological states, pain levels, quality of life, sleep quality, and nurse satisfaction were compared before to and during the intervention.</p><p><strong>Results: </strong>Compared with the control group, the self-rating anxiety scale (SAS) score, self-rating depression scale (SDS) score, visual analog scale (VAS) score, and Pittsburgh Sleep Quality Index (PSQI) score of the observation group significantly decreased after intervention, while the short-form 36 (SF-36) score significantly increased (<i>P</i> < 0.05). The SAS score decreased by 17.36%; SDS score decreased by 26.21%. The VAS scores decreased by 57.14%, 63.43%, and 69.86% at 12 hours, 24 hours and 48 hours, respectively. The SF-36 score indicators increased by 13.29%, 13.24%, 20.77%, and 19.41%, respectively; The PSQI score decreased by 54.66%. The observation group reported higher nurse satisfaction.</p><p><strong>Conclusion: </strong>Comprehensive psychological cognitive nursing interventions can significantly reduce patients' pain and depression symptoms while boosting their confidence in managing the illness.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"107534"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression in postmenopausal women with osteoporosis: Integrating psychological nursing into holistic care.","authors":"Jin-Yuan Zhu, Adilijiang Yiming, Jing-Qi Zeng","doi":"10.5498/wjp.v15.i9.110536","DOIUrl":"10.5498/wjp.v15.i9.110536","url":null,"abstract":"<p><p>Depression is highly prevalent among postmenopausal women with osteoporosis, driven by the combined effects of hormonal changes, reduced bone density, and psychosocial stress. A recent study by Cui and Su reported that 73.3% of affected women exhibited depressive symptoms, with low bone mineral density, chronic comorbidities, and reduced serotonin (5-hydroxytryptamine) levels as key risk factors. Notably, nurse-led psychological interventions improved both mood and quality of life. This editorial underscore the need to integrate mental health support into standard osteoporosis care. Simple, scalable strategies such as routine screening and nurse-delivered emotional support may help bridge the gap between physical and psychological health. These approaches are especially relevant for aging populations across diverse healthcare settings. A dual focus on bone and emotional well-being is essential to improving outcomes in this vulnerable group.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"110536"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of postpartum persistent depression on infant developmental behavior and maternal self-efficacy.","authors":"Shu-Juan Wu, Jing-Xian Wang, Xiu-Lei Yin, Ying He, Hui-Xian Kang","doi":"10.5498/wjp.v15.i9.110656","DOIUrl":"10.5498/wjp.v15.i9.110656","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Postpartum depression (PPD) represents a significant public health concern, adversely affecting both new mothers and their infants. Despite routine early screening, PPD can persist beyond the initial postpartum months, with notably high incidence rates even one year after childbirth. Persistent PPD has been associated with poor developmental outcomes in infants, highlighting the need for continued monitoring and support during this critical period. Understanding the broader impacts of persistent PPD is essential for developing effective interventions to improve maternal and infant well-being.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To explore the impact of persistent PPD on infant developmental behavior and maternal self-efficacy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We recruited 60 postpartum women who experienced persistent depression after childbirth in our hospital from January 2020 to December 2024 as the research subjects. The study collected basic characteristics of both infants and mothers, analyzed the self-efficacy of the mothers and the developmental behaviors of the infants, and conducted a correlation analysis to examine the relationship between postpartum persistent depression in mothers and the developmental behaviors and self-efficacy of infants. The Bootstrap method was used to verify the significance of the mediating effect.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The basic characteristics of infants and mothers show that 53.33% are male, 58.33% are born &lt;i&gt;via&lt;/i&gt; vaginal delivery, 88.33% have a normal body mass index, 51.67% are aged between 25 and 29 years, 70% are non-agricultural workers, 51.67% have a per capita household income over 4000 yuan, 96.67% are full-term births, and 58.33% of the fathers are aged between 26 and 32 years. In terms of infant development behavior, the gross motor skills score is relatively low (38.44 ± 12.15). Regarding maternal self-efficacy, the skill score (45.68 ± 5.49) and mental activity score (46.37 ± 3.72) are both at a low level. Correlation analysis reveals that postpartum persistent depression is significantly negatively correlated with maternal self-efficacy and infant development behavior (&lt;i&gt;β&lt;/i&gt; = -0.439, -0.657, &lt;i&gt;P&lt;/i&gt; &lt; 0.001), while self-efficacy is positively correlated with infant development behavior (&lt;i&gt;β&lt;/i&gt; = 0.728, &lt;i&gt;P&lt;/i&gt; &lt; 0.001). The path coefficient and Bootstrap method test indicate that self-efficacy acts as a mediator between postpartum persistent depression and infant development behavior, accounting for 54.80% of the effect (&lt;i&gt;P&lt;/i&gt; &lt; 0.05), while the direct effect of postpartum persistent depression on infant development behavior is 45.20% (&lt;i&gt;P&lt;/i&gt; &lt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Persistent PPD significantly negatively impacts infant developmental outcomes, with maternal self-efficacy serving as a partial mediator. These findings suggest that interventions targeting both depressive symptoms and self-enhancement may effectively promote infa","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"110656"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of childhood trauma and parental socialization on at-risk mental state in non-clinical adolescents.","authors":"Antonio Jovani, Balma Moliner-Castellano, Rita Gimeno Vergara, Ana Benito, María Isabel Marí-Sanmillán, Francisca Castellano-García, Gonzalo Haro","doi":"10.5498/wjp.v15.i9.108465","DOIUrl":"10.5498/wjp.v15.i9.108465","url":null,"abstract":"<p><strong>Background: </strong>Childhood trauma and parental socialization have been postulated as environmental factors of at-risk mental state (ARMS). Parental socialization is the process through which parents shape children's self-regulation by providing guidance and protection. Although the impact of trauma on ARMS has been theorized, its clinical implications have not yet been fully clarified in adolescence, nor have explanatory models of parenting styles been established.</p><p><strong>Aim: </strong>To investigate the role of traumatic experiences in the appearance of ARMS in the general adolescent population, considering the influence of parental socialization.</p><p><strong>Methods: </strong>A cross-sectional study of 697 adolescents aged 11-15 years was conducted, during which several questionnaires assessing childhood trauma, psychotic symptoms, and parenting styles were administered. The sample was divided into control, low-risk, medium-risk, and high-risk groups.</p><p><strong>Results: </strong>Some 2.8% (<i>n</i> = 19) of the adolescents presented ARMS and the presence of childhood trauma was associated with an increased risk of ARMS. Furthermore, the presence of abuse was greater in the high-risk and low-risk groups compared to controls. Regarding parental socialization, it was determined that a family socialization style based on greater affection-communication decreased the probability of ARMS. Finally, using PROCESS model 1 (regression-based path analysis that uses ordinary least squares regression), results suggested that low levels of affection and communication may mediate the relationship between childhood trauma and ARMS in adolescents.</p><p><strong>Conclusion: </strong>These results highlight the importance of the early detection of trauma in preventing ARMS, without forgetting the importance of socialization styles.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 9","pages":"108465"},"PeriodicalIF":3.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}