{"title":"Selective serotonin reuptake inhibitors in the treatment of major depressive disorder after brain trauma: Systematic review and meta-analysis.","authors":"Ren-Xian Gao, Xiao-Na Zhang, Peng Zhu","doi":"10.5498/wjp.v15.i3.100103","DOIUrl":"10.5498/wjp.v15.i3.100103","url":null,"abstract":"<p><strong>Background: </strong>Traumatic brain injury (TBI) poses a considerable risk to human health. After TBI, individuals are susceptible to a range of psychiatric disorders, with depression being a primary complication. Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment of depression; however, their efficacy in addressing major depressive disorder (MDD) in adults following TBI remains uncertain.</p><p><strong>Aim: </strong>To investigate the efficacy of SSRIs in the treatment of MDD after TBI.</p><p><strong>Methods: </strong>A comprehensive search across multiple databases was conducted following the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, encompassing studies published until May 2024. This review focused on studies that examined the efficacy of SSRIs in the treatment of MDD following TBI. Studies were assessed based sample size, treatment duration, treatment methodologies, severity of brain injury, assessment techniques, and drug response. A random-effects model was used to derive the summary effect size.</p><p><strong>Results: </strong>Eight studies compared the reduction in depression scores in patients with MDD after TBI and SSRI treatment. The eight studies did not exhibit heterogeneity (<i>I</i> <sup>2</sup> = 38%). The depression score for MDD after TBI in the SSRI group decreased more than that in the control group [odds ratio (OR) 1.68, 95%CI: 1.09-2.58, <i>P</i> = 0.02]. The adverse reactions after treatment included diarrhea, dizziness, dry mouth, nausea, or vomiting. There was no difference in the incidence of adverse reactions after treatment between the two groups (OR 1.16, 95%CI: 0.78-1.73, <i>P</i> = 0.46]. These studies did not show significant heterogeneity (<i>I</i> <sup>2</sup> = 44%).</p><p><strong>Conclusion: </strong>SSRIs may be effective in treating patients with MDD after TBI. Adequately powered, randomized, controlled trials are required to confirm these findings.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100103"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can decoding the complex web of non-suicidal self-injury in adolescents pave the way for tailored interventions?","authors":"Haewon Byeon","doi":"10.5498/wjp.v15.i3.103258","DOIUrl":"10.5498/wjp.v15.i3.103258","url":null,"abstract":"<p><p>Non-suicidal self-injury (NSSI) is a prevalent and concerning issue in adolescent mental health, often intertwined with depressive symptoms. Despite extensive research on NSSI, a comprehensive understanding of its multifaceted nature and the intricate interplay of risk and resilience factors remains crucial. This Letter to the Editor examines a novel study by Yang <i>et al</i>, which utilized latent profile analysis and network analysis to delineate distinct NSSI subtypes within a Chinese adolescent population and investigate the underlying dynamics of associated factors. The study identifies three distinct NSSI subtypes: NSSI with depression, NSSI without depression, and neither, underscoring bullying as a prominent risk factor. Concurrently, the findings emphasized the pivotal role of emotional regulation and family support as protective factors. The focus of this article is to contextualize these findings within the broader framework of adolescent mental health and to highlight their implications for developing targeted interventions. These insights not only advance our understanding of adolescent NSSI but also provide a foundation for the development of targeted interventions that address the identified risk and protective factors. By focusing on these critical areas, mental health professionals can implement more effective strategies to mitigate NSSI behaviors and cultivate resilience in this vulnerable population.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103258"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Impact of comorbid subthreshold depressive symptoms on cancer-related fatigue and complications in adults with leukemia.","authors":"Yue-Xian Liu, Juan Wang","doi":"10.5498/wjp.v15.i3.103446","DOIUrl":"10.5498/wjp.v15.i3.103446","url":null,"abstract":"<p><p>[This corrects the article on p. 1009 in vol. 14, PMID: 39050202.].</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103446"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychological consistency network characteristics and influencing factors in patients after percutaneous coronary intervention treatment.","authors":"Yue Li, Liang-Hong Wang, Huan Zeng, Yan Zhao, Yao-Qiong Lu, Tian-Ying Zhang, Hai-Bin Luo, Feng Tang","doi":"10.5498/wjp.v15.i3.102571","DOIUrl":"10.5498/wjp.v15.i3.102571","url":null,"abstract":"<p><strong>Background: </strong>A psychological sense of coherence (SOC) in percutaneous coronary intervention (PCI) patients is important for disease prognosis, and there is considerable variation between their symptoms. In contrast, network analysis provides a new approach to gaining insight into the complex nature of symptoms and symptom clusters and identifying core symptoms.</p><p><strong>Aim: </strong>To explore the psychological coherence of symptoms experienced by PCI patients, we aim to analyze differences in their associated factors and employ network analysis to characterize the symptom networks.</p><p><strong>Methods: </strong>A total of 472 patients who underwent PCI were selected for a cross-sectional study. The objective was to investigate the association between general patient demographics, medical coping styles, perceived stress status, and symptoms of psychological coherence. Data analysis was conducted using a linear regression model and a network model to visualize psychological coherence and calculate a centrality index.</p><p><strong>Results: </strong>Post-PCI patients exhibited low levels of psychological coherence, which correlated with factors such as education, income, age, place of residence, adherence to medical examinations, perceived stress, and medical coping style. Network analysis revealed that symptoms within the sense of psychological coherence were strongly interconnected, particularly with SOC2 and SOC8, demonstrating the strongest correlations. Among these, SOC10 emerged as the symptom with the highest intensity, centrality, and proximity, identifying it as the most central symptom.</p><p><strong>Conclusion: </strong>The network model has strong explanatory power in describing the psychological consistency symptoms of patients after PCI, identifying the central SOC symptoms, among which SOC10 is the key to overall SOC enhancement, and there is a strong positive correlation between SOC2 and SOC8, emphasizing the need to consider the synergistic effect of symptoms in intervention measures.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102571"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei Zhao, Wei-Guan Chen, Long-Yao Zhang, Zhi-Ming Cui, Xue-Jian Wang
{"title":"Impact of depression, anxiety, inflammatory factors, and stress levels on treatment outcomes in patients with chronic trauma.","authors":"Wei Zhao, Wei-Guan Chen, Long-Yao Zhang, Zhi-Ming Cui, Xue-Jian Wang","doi":"10.5498/wjp.v15.i3.103250","DOIUrl":"10.5498/wjp.v15.i3.103250","url":null,"abstract":"<p><p>This editorial discusses a recent article published by Li <i>et al</i> in 2024, which highlights a critical yet underexplored dimension of chronic wound care: The impact of psychological factors such as depression and anxiety on treatment outcomes. With the increasing prevalence of chronic wounds in China, driven by population aging, traffic accidents, and chronic diseases, chronic wounds have emerged as a significant public health concern. They not only pose serious threats to individual health but also impose considerable social and economic burdens on healthcare systems. Against this backdrop, the study by Li <i>et al</i> aimed to explore how psychological distress affects the management and recovery of patients with chronic wounds. In their research, chronic wound patients were meticulously evaluated for depression and anxiety using validated psychological assessment scales and blood biomarkers. The findings reveal a stark reality: Individuals with severe depression and anxiety exhibit markedly lower treatment adherence, slower recovery rates, and diminished post-treatment quality of life. These psychological challenges hinder patients' active engagement with their care plans and may directly impede physiological healing processes. Importantly, the study underscored that factors such as wound size, anxiety, and depression significantly influence therapeutic outcomes in chronic wound patients. This insight calls for a more holistic approach to wound care, where addressing psychological well-being becomes an integral component of treatment protocols. As such, the study highlighted the necessity of early identification and targeted intervention for depression and anxiety in chronic wound patients. By prioritizing psychological support alongside medical treatment, healthcare providers can enhance therapeutic efficacy and improve patients' long-term quality of life. This integrative approach can not only optimize clinical outcomes but also alleviate the broader societal and economic impact of chronic wounds.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103250"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ai-Ming Gu, Chao Liang, Chao Liu, Ru-Ya Guo, Jin Hu, Xing-Shi Chen, Jun-Jie Xu, Jie Huang
{"title":"Repetitive transcranial magnetic stimulation guided by event-related potential P300 application in schizophrenia.","authors":"Ai-Ming Gu, Chao Liang, Chao Liu, Ru-Ya Guo, Jin Hu, Xing-Shi Chen, Jun-Jie Xu, Jie Huang","doi":"10.5498/wjp.v15.i3.100120","DOIUrl":"10.5498/wjp.v15.i3.100120","url":null,"abstract":"<p><strong>Background: </strong>Repetitive transcranial magnetic stimulation (rTMS) entered clinical practice in China after 2000, first used in psychiatric surgery, and then in neurology and other disciplines. The First Hospital of Jiaxing introduced TMS in 2015. In practical applications, it has been found that different models of instruments and technical parameters can lead to differences in therapeutic efficacy. Therefore, our hospital selected the Danish TMS instrument, which ranks second in China, to test patients with schizophrenia from March 2021 to July 2021, with a focus on comparing the results at 5 Hz, 10 Hz, and 15 Hz. The testing time is concentrated between 8:30 to 10:30 in the morning. A contingency plan was made for the quality after inspection before testing. Two evaluators independently control the quality of the contingency plan. The data is independently saved and proofread by two evaluators. The purpose of this study is to translate the research results into clinical practice and provide reference basis.</p><p><strong>Aim: </strong>To investigate the effects of rehabilitation therapy using rTMS on the negative symptoms and event-related potential component of P300 in chronic schizophrenia.</p><p><strong>Methods: </strong>One hundred and five patients with chronic schizophrenia were randomly allocated to three groups based on the frequency of rTMS (5, 10, or 15 Hz). The patients underwent five sessions of rTMS per week for 5 weeks. We compared the pre- and post-treatment P300 latency and scores for the Scale for Assessment of Negative Symptoms (SANS).</p><p><strong>Results: </strong>A significant decrease in SANS score after rTMS was observed in the 10-Hz group (<i>P</i> < 0.05), which was not observed in the 5-Hz and 15-Hz groups. There was a significant increase in P300 amplitude in the 10-Hz group after rTMS treatment (<i>P</i> < 0.05), but there was no significant change in P300 latency (<i>P</i> > 0.05). The improvement of SANS score in the 10-Hz rTMS group was related to patient age and disease course.</p><p><strong>Conclusion: </strong>rTMS at 10 Hz improved negative symptoms and cognitive function in chronic schizophrenia; however, further studies on the mechanism of action are required to validate our observations.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100120"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of anxiety and depression status and related factors among mothers of children in neonatal intensive care unit.","authors":"Fen Xu, Ling-Ling Shi, Li Gao","doi":"10.5498/wjp.v15.i3.101748","DOIUrl":"10.5498/wjp.v15.i3.101748","url":null,"abstract":"<p><strong>Background: </strong>Newborns are immediately admitted to the neonatal intensive care unit (NICU) after birth, and thus mothers suffer from the pain of mother-infant separation. Some mothers worry about alterations in their child's condition and the uncertainty and high medical costs of possible sequelae, which frequently cause anxiety, depression, and other adverse emotions.</p><p><strong>Aim: </strong>To investigate the anxiety and depression status of mothers of children in the NICU and its related factors.</p><p><strong>Methods: </strong>A convenient sampling method is adopted. The research objects included the mothers of 191 children in the NICU of Suzhou Ninth Hospital Affiliated with Suzhou University from January 2023 to July 2024. The general information questionnaire, personal control scale, self-rating anxiety scale, and self-rating depression scale were utilized for investigation. Anxiety and depression status in mothers of children in the NICU and its related factors were analyzed.</p><p><strong>Results: </strong>The incidences of maternal anxiety and depression among 191 hospitalized children in the NICU were 32.98% (63/191) and 23.56% (45/191), respectively. Single-factor analysis reveals that family monthly income, individual sense of control, gestational age of the child, and the number of diseases in the child are associated with the anxiety and depression experienced by the mother of the child in the NICU (<i>P</i> < 0.05). Multivariate logistic regression analysis revealed that family monthly income of < 5000 yuan (RMB), poor individual control, gestational age of < 32 weeks, and the number of diseases of ≥ 3 kinds are all related factors for anxiety and depression in mothers of children admitted to the NICU (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Mothers of children admitted to the NICU demonstrated high anxiety and depression incidences. The nursing staff in the neonatal department established intervention measures for each related factor, strengthened communication and communication with the mother of the child, and did a good job in psychological counseling.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101748"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chen-Chen Xu, Wen-Xuan Zhao, Yu Sheng, Ya-Jun Yun, Ting Ma, Ning Fan, Jia-Qi Song, Jun Wang, Qi Zhang
{"title":"Serum homocysteine showed potential association with cognition and abnormal gut microbiome in major depressive disorder.","authors":"Chen-Chen Xu, Wen-Xuan Zhao, Yu Sheng, Ya-Jun Yun, Ting Ma, Ning Fan, Jia-Qi Song, Jun Wang, Qi Zhang","doi":"10.5498/wjp.v15.i3.102567","DOIUrl":"10.5498/wjp.v15.i3.102567","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment is one of the common clinical manifestations of depression, causing negative distress to patients. Elevated homocysteine (Hcy) concentrations and gut microbiome dysfunction may be observed in patients with depression.</p><p><strong>Aim: </strong>To investigate the relationship between Hcy, microbiome, and cognition in depressive patients.</p><p><strong>Methods: </strong>We recruited 67 patients with major depressive disorder (MDD) (MDD group) and 94 healthy controls (HCs) individuals (HCs group). Serum Hcy levels were determined using the enzyme circulation method. 16s rRNA sequencing was used to classify and identify the fecal bacteria. 17 Hamilton depression rating scale and MATRICS consensus cognitive battery were used to evaluate mood states and cognition in patients with MDD. Correlation analysis was performed to explore the correlation between fecal flora, Hcy, and depressive cognitive function.</p><p><strong>Results: </strong>Elevated serum levels of Hcy were seen in patients with MDD compared to healthy individuals. Patients with MDD indicated significant decreases in cognitive scores (<i>P</i> < 0.001) in six modules: Speed of processing, working memory, visual learning, reasoning and problem-solving, social cognition, and total scores. Hcy levels showed a negative correlation with processing speed, social cognition, and total MDD scores (<i>P <</i> 0.05). Hcy was also significantly negatively correlated with <i>Alistipes</i>, <i>Ruminococcae</i>, <i>Tenericides</i>, and <i>Porphyromonas</i> (<i>P <</i> 0.05).</p><p><strong>Conclusion: </strong>Our results highlight that Hcy was correlated with cognition and gut microbiome in MDD. This interaction may be related to the physiological and pathological mechanisms underlying cognitive deficits in depression.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102567"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shu-Wen Dong, Lei Yang, Yi-Fan Lin, Li-Wen Yang, Dan Li, Li-Wan Zhu, Cai-Yun Zhang, Yan-Zhi Li, Wan-Xin Wang, Ci-Yong Lu, Bin Yan
{"title":"Sex and age differences in depression and anxiety networks among adolescents with idiopathic scoliosis: A network analysis.","authors":"Shu-Wen Dong, Lei Yang, Yi-Fan Lin, Li-Wen Yang, Dan Li, Li-Wan Zhu, Cai-Yun Zhang, Yan-Zhi Li, Wan-Xin Wang, Ci-Yong Lu, Bin Yan","doi":"10.5498/wjp.v15.i3.102790","DOIUrl":"10.5498/wjp.v15.i3.102790","url":null,"abstract":"<p><strong>Background: </strong>Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis (AIS), affecting individuals across both sex and age groups.</p><p><strong>Aim: </strong>To explore the network structure of depression and anxiety symptoms, with a focus on identifying differences at the symptom level between sex and age subgroups.</p><p><strong>Methods: </strong>A total of 1955 participants diagnosed with AIS aged 10-18 years were assessed using the Patient Health Questionnaire Depression Scale (PHO-9) and the Generalized Anxiety Disorder Scale (GAD-7), and 765 patients exhibiting PHQ-9 or GAD-7 scores ≥ 5 were enrolled in our study. Network analysis and network comparison tests were utilized to construct and compare the depression-anxiety symptoms networks among sex and age subgroups.</p><p><strong>Results: </strong>The results revealed GAD3 \"Excessive worry\" and PHQ2 \"Sad mood\" were the most significant central symptoms in all subgroups, while \"Sad mood\" had higher strength than \"Excessive worry\" in the lower age group. In the network comparisons, the female network exhibited tighter connectivity, especially on GAD6 \"Irritability\" and GAD2 \"Uncontrollable worry\", while only PHQ3 \"Sleep\" and PHQ9 \"Suicidal ideation\" had differences at the local level in the lower age group.</p><p><strong>Conclusion: </strong>Several interventions targeting excessive worry and sad mood could reduce the risk of depression and anxiety symptoms in the AIS population. Furthermore, specific anxiety symptoms in females, along with sleep disturbances and suicidal ideation in the lower age group, should be addressed at an early stage to prevent significant disruptions in mental health trajectories.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102790"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Attention to cancer-related physical and mental fatigue: Breaking the vicious cycle.","authors":"Yan Zeng, Jun-Wen Zhang, Jian Yang","doi":"10.5498/wjp.v15.i3.99037","DOIUrl":"10.5498/wjp.v15.i3.99037","url":null,"abstract":"<p><p>Cancer-related fatigue (CRF) presents as a complex interplay between physical and mental fatigue, with mindfulness interventions offering a promising approach to alleviate both. These techniques, including mindfulness-based stress reduction, cognitive therapy, dialectical behavior therapy, and acceptance and commitment therapy, are designed to break the cycle of CRF by addressing its psychological and emotional aspects. This editorial integrates the latest research published by Liu <i>et al</i>, examining the reciprocal and harmful cyclical relationship between physical and mental CRF, and explores the causes and associated mindfulness interventions. We expect that future research will emphasize the identification and management of CRF, particularly focusing on the application of various mindfulness interventions in cancer survivors and patients undergoing cancer treatment, as well as the development of mindfulness in the era of new technologies.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99037"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}