World Journal of Psychiatry最新文献

{"title":"Impact of depression, anxiety, inflammatory factors, and stress levels on treatment outcomes in patients with chronic trauma.","authors":"Wei Zhao, Wei-Guan Chen, Long-Yao Zhang, Zhi-Ming Cui, Xue-Jian Wang","doi":"10.5498/wjp.v15.i3.103250","DOIUrl":"10.5498/wjp.v15.i3.103250","url":null,"abstract":"<p><p>This editorial discusses a recent article published by Li <i>et al</i> in 2024, which highlights a critical yet underexplored dimension of chronic wound care: The impact of psychological factors such as depression and anxiety on treatment outcomes. With the increasing prevalence of chronic wounds in China, driven by population aging, traffic accidents, and chronic diseases, chronic wounds have emerged as a significant public health concern. They not only pose serious threats to individual health but also impose considerable social and economic burdens on healthcare systems. Against this backdrop, the study by Li <i>et al</i> aimed to explore how psychological distress affects the management and recovery of patients with chronic wounds. In their research, chronic wound patients were meticulously evaluated for depression and anxiety using validated psychological assessment scales and blood biomarkers. The findings reveal a stark reality: Individuals with severe depression and anxiety exhibit markedly lower treatment adherence, slower recovery rates, and diminished post-treatment quality of life. These psychological challenges hinder patients' active engagement with their care plans and may directly impede physiological healing processes. Importantly, the study underscored that factors such as wound size, anxiety, and depression significantly influence therapeutic outcomes in chronic wound patients. This insight calls for a more holistic approach to wound care, where addressing psychological well-being becomes an integral component of treatment protocols. As such, the study highlighted the necessity of early identification and targeted intervention for depression and anxiety in chronic wound patients. By prioritizing psychological support alongside medical treatment, healthcare providers can enhance therapeutic efficacy and improve patients' long-term quality of life. This integrative approach can not only optimize clinical outcomes but also alleviate the broader societal and economic impact of chronic wounds.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103250"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repetitive transcranial magnetic stimulation guided by event-related potential P300 application in schizophrenia.","authors":"Ai-Ming Gu, Chao Liang, Chao Liu, Ru-Ya Guo, Jin Hu, Xing-Shi Chen, Jun-Jie Xu, Jie Huang","doi":"10.5498/wjp.v15.i3.100120","DOIUrl":"10.5498/wjp.v15.i3.100120","url":null,"abstract":"<p><strong>Background: </strong>Repetitive transcranial magnetic stimulation (rTMS) entered clinical practice in China after 2000, first used in psychiatric surgery, and then in neurology and other disciplines. The First Hospital of Jiaxing introduced TMS in 2015. In practical applications, it has been found that different models of instruments and technical parameters can lead to differences in therapeutic efficacy. Therefore, our hospital selected the Danish TMS instrument, which ranks second in China, to test patients with schizophrenia from March 2021 to July 2021, with a focus on comparing the results at 5 Hz, 10 Hz, and 15 Hz. The testing time is concentrated between 8:30 to 10:30 in the morning. A contingency plan was made for the quality after inspection before testing. Two evaluators independently control the quality of the contingency plan. The data is independently saved and proofread by two evaluators. The purpose of this study is to translate the research results into clinical practice and provide reference basis.</p><p><strong>Aim: </strong>To investigate the effects of rehabilitation therapy using rTMS on the negative symptoms and event-related potential component of P300 in chronic schizophrenia.</p><p><strong>Methods: </strong>One hundred and five patients with chronic schizophrenia were randomly allocated to three groups based on the frequency of rTMS (5, 10, or 15 Hz). The patients underwent five sessions of rTMS per week for 5 weeks. We compared the pre- and post-treatment P300 latency and scores for the Scale for Assessment of Negative Symptoms (SANS).</p><p><strong>Results: </strong>A significant decrease in SANS score after rTMS was observed in the 10-Hz group (<i>P</i> < 0.05), which was not observed in the 5-Hz and 15-Hz groups. There was a significant increase in P300 amplitude in the 10-Hz group after rTMS treatment (<i>P</i> < 0.05), but there was no significant change in P300 latency (<i>P</i> > 0.05). The improvement of SANS score in the 10-Hz rTMS group was related to patient age and disease course.</p><p><strong>Conclusion: </strong>rTMS at 10 Hz improved negative symptoms and cognitive function in chronic schizophrenia; however, further studies on the mechanism of action are required to validate our observations.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100120"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attention to cancer-related physical and mental fatigue: Breaking the vicious cycle.","authors":"Yan Zeng, Jun-Wen Zhang, Jian Yang","doi":"10.5498/wjp.v15.i3.99037","DOIUrl":"10.5498/wjp.v15.i3.99037","url":null,"abstract":"<p><p>Cancer-related fatigue (CRF) presents as a complex interplay between physical and mental fatigue, with mindfulness interventions offering a promising approach to alleviate both. These techniques, including mindfulness-based stress reduction, cognitive therapy, dialectical behavior therapy, and acceptance and commitment therapy, are designed to break the cycle of CRF by addressing its psychological and emotional aspects. This editorial integrates the latest research published by Liu <i>et al</i>, examining the reciprocal and harmful cyclical relationship between physical and mental CRF, and explores the causes and associated mindfulness interventions. We expect that future research will emphasize the identification and management of CRF, particularly focusing on the application of various mindfulness interventions in cancer survivors and patients undergoing cancer treatment, as well as the development of mindfulness in the era of new technologies.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99037"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of anxiety and depression status and related factors among mothers of children in neonatal intensive care unit.","authors":"Fen Xu, Ling-Ling Shi, Li Gao","doi":"10.5498/wjp.v15.i3.101748","DOIUrl":"10.5498/wjp.v15.i3.101748","url":null,"abstract":"<p><strong>Background: </strong>Newborns are immediately admitted to the neonatal intensive care unit (NICU) after birth, and thus mothers suffer from the pain of mother-infant separation. Some mothers worry about alterations in their child's condition and the uncertainty and high medical costs of possible sequelae, which frequently cause anxiety, depression, and other adverse emotions.</p><p><strong>Aim: </strong>To investigate the anxiety and depression status of mothers of children in the NICU and its related factors.</p><p><strong>Methods: </strong>A convenient sampling method is adopted. The research objects included the mothers of 191 children in the NICU of Suzhou Ninth Hospital Affiliated with Suzhou University from January 2023 to July 2024. The general information questionnaire, personal control scale, self-rating anxiety scale, and self-rating depression scale were utilized for investigation. Anxiety and depression status in mothers of children in the NICU and its related factors were analyzed.</p><p><strong>Results: </strong>The incidences of maternal anxiety and depression among 191 hospitalized children in the NICU were 32.98% (63/191) and 23.56% (45/191), respectively. Single-factor analysis reveals that family monthly income, individual sense of control, gestational age of the child, and the number of diseases in the child are associated with the anxiety and depression experienced by the mother of the child in the NICU (<i>P</i> < 0.05). Multivariate logistic regression analysis revealed that family monthly income of < 5000 yuan (RMB), poor individual control, gestational age of < 32 weeks, and the number of diseases of ≥ 3 kinds are all related factors for anxiety and depression in mothers of children admitted to the NICU (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Mothers of children admitted to the NICU demonstrated high anxiety and depression incidences. The nursing staff in the neonatal department established intervention measures for each related factor, strengthened communication and communication with the mother of the child, and did a good job in psychological counseling.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101748"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum homocysteine showed potential association with cognition and abnormal gut microbiome in major depressive disorder.","authors":"Chen-Chen Xu, Wen-Xuan Zhao, Yu Sheng, Ya-Jun Yun, Ting Ma, Ning Fan, Jia-Qi Song, Jun Wang, Qi Zhang","doi":"10.5498/wjp.v15.i3.102567","DOIUrl":"10.5498/wjp.v15.i3.102567","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment is one of the common clinical manifestations of depression, causing negative distress to patients. Elevated homocysteine (Hcy) concentrations and gut microbiome dysfunction may be observed in patients with depression.</p><p><strong>Aim: </strong>To investigate the relationship between Hcy, microbiome, and cognition in depressive patients.</p><p><strong>Methods: </strong>We recruited 67 patients with major depressive disorder (MDD) (MDD group) and 94 healthy controls (HCs) individuals (HCs group). Serum Hcy levels were determined using the enzyme circulation method. 16s rRNA sequencing was used to classify and identify the fecal bacteria. 17 Hamilton depression rating scale and MATRICS consensus cognitive battery were used to evaluate mood states and cognition in patients with MDD. Correlation analysis was performed to explore the correlation between fecal flora, Hcy, and depressive cognitive function.</p><p><strong>Results: </strong>Elevated serum levels of Hcy were seen in patients with MDD compared to healthy individuals. Patients with MDD indicated significant decreases in cognitive scores (<i>P</i> < 0.001) in six modules: Speed of processing, working memory, visual learning, reasoning and problem-solving, social cognition, and total scores. Hcy levels showed a negative correlation with processing speed, social cognition, and total MDD scores (<i>P <</i> 0.05). Hcy was also significantly negatively correlated with <i>Alistipes</i>, <i>Ruminococcae</i>, <i>Tenericides</i>, and <i>Porphyromonas</i> (<i>P <</i> 0.05).</p><p><strong>Conclusion: </strong>Our results highlight that Hcy was correlated with cognition and gut microbiome in MDD. This interaction may be related to the physiological and pathological mechanisms underlying cognitive deficits in depression.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102567"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex and age differences in depression and anxiety networks among adolescents with idiopathic scoliosis: A network analysis.","authors":"Shu-Wen Dong, Lei Yang, Yi-Fan Lin, Li-Wen Yang, Dan Li, Li-Wan Zhu, Cai-Yun Zhang, Yan-Zhi Li, Wan-Xin Wang, Ci-Yong Lu, Bin Yan","doi":"10.5498/wjp.v15.i3.102790","DOIUrl":"10.5498/wjp.v15.i3.102790","url":null,"abstract":"<p><strong>Background: </strong>Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis (AIS), affecting individuals across both sex and age groups.</p><p><strong>Aim: </strong>To explore the network structure of depression and anxiety symptoms, with a focus on identifying differences at the symptom level between sex and age subgroups.</p><p><strong>Methods: </strong>A total of 1955 participants diagnosed with AIS aged 10-18 years were assessed using the Patient Health Questionnaire Depression Scale (PHO-9) and the Generalized Anxiety Disorder Scale (GAD-7), and 765 patients exhibiting PHQ-9 or GAD-7 scores ≥ 5 were enrolled in our study. Network analysis and network comparison tests were utilized to construct and compare the depression-anxiety symptoms networks among sex and age subgroups.</p><p><strong>Results: </strong>The results revealed GAD3 \"Excessive worry\" and PHQ2 \"Sad mood\" were the most significant central symptoms in all subgroups, while \"Sad mood\" had higher strength than \"Excessive worry\" in the lower age group. In the network comparisons, the female network exhibited tighter connectivity, especially on GAD6 \"Irritability\" and GAD2 \"Uncontrollable worry\", while only PHQ3 \"Sleep\" and PHQ9 \"Suicidal ideation\" had differences at the local level in the lower age group.</p><p><strong>Conclusion: </strong>Several interventions targeting excessive worry and sad mood could reduce the risk of depression and anxiety symptoms in the AIS population. Furthermore, specific anxiety symptoms in females, along with sleep disturbances and suicidal ideation in the lower age group, should be addressed at an early stage to prevent significant disruptions in mental health trajectories.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102790"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catatonia in an acute adult inpatient population in mental health units in Khartoum, Sudan: A cross-sectional study.","authors":"Maysoon B Idrees, Abla M Elmahdi, Hatim Y Alharbi, Ishag Adam","doi":"10.5498/wjp.v15.i3.102529","DOIUrl":"10.5498/wjp.v15.i3.102529","url":null,"abstract":"<p><strong>Background: </strong>Catatonic syndrome is a mental health issue, as well as a medical, neurological, and toxic condition. There are few published data on catatonic syndrome in African countries and none in Sudan, the third-largest African country.</p><p><strong>Aim: </strong>To assess the prevalence and presenting symptoms of catatonic syndrome in an acute psychiatric inpatient population in four governmental psychiatric hospitals in Sudan.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in four psychiatric hospitals in the capital, Khartoum, in Sudan. The data were collected using an interviewer-administered questionnaire tool, which included sociodemographic data (age, sex, educational level, marital status, and residence). Signs and symptoms of catatonic syndrome were assessed using the Bush-Francis Catatonia Rating Scale (BFCRS) and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnostic criteria. <i>χ²</i> tests were used to compare categorized variables. Multivariate analysis was not performed because none of the variables were found to be different between patients with and without catatonic syndrome.</p><p><strong>Results: </strong>Of the 384 patients, 50.0% and 49.3% were males and females, respectively, and their median age was 30.0 years. One hundred and sixty-three (42.4%) patients had catatonic syndrome according to the BFCRS criteria. Of these patients, 104 fulfilled the DSM-5 criteria, with a 27.1% prevalence of catatonic syndrome. Echopraxia/echolalia (84.5%), mutism (71.2%), posturing/catalepsy (67.3%), and mannerisms (66.3%) were the main manifestations among patients with catatonic syndrome. There was no significant difference in age, sex, marital status, or job between patients with and those without catatonic syndrome. Of the 163 patients with catatonic syndrome, 31.3% had bipolar disorder, 28.2% had schizophrenia, and 19.6% had major depressive disorder.</p><p><strong>Conclusion: </strong>Catatonic syndrome is highly prevalent in an acute psychiatric inpatient population in Sudan regardless of age or sex. Echopraxia/echolalia (84.5%) and mutism were the main manifestations among the patients with catatonic syndrome.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102529"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific psychiatry within technical reach.","authors":"Diyana Najar, Drozdstoy Stoyanov","doi":"10.5498/wjp.v15.i3.101142","DOIUrl":"10.5498/wjp.v15.i3.101142","url":null,"abstract":"<p><p>This is an invited commentary on the paper by Zou <i>et al</i>, accepted for publication in <i>World Journal of Psychiatry</i>. It reflects the findings of the authors in the broader context of the search for scientifically sound and evidence based nomothetic system for diagnosis and treatment in psychiatry, with a special focus on the application of translational neuroimaging in that effort.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101142"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing the diagnosis of major depressive disorder: Integrating neuroimaging and machine learning.","authors":"Shi-Qi Yin, Ying-Huan Li","doi":"10.5498/wjp.v15.i3.103321","DOIUrl":"10.5498/wjp.v15.i3.103321","url":null,"abstract":"<p><p>Major depressive disorder (MDD), a psychiatric disorder characterized by functional brain deficits, poses considerable diagnostic and treatment challenges, especially in adolescents owing to varying clinical presentations. Biomarkers hold substantial clinical potential in the field of mental health, enabling objective assessments of physiological and pathological states, facilitating early diagnosis, and enhancing clinical decision-making and patient outcomes. Recent breakthroughs combine neuroimaging with machine learning (ML) to distinguish brain activity patterns between MDD patients and healthy controls, paving the way for diagnostic support and personalized treatment. However, the accuracy of the results depends on the selection of neuroimaging features and algorithms. Ensuring privacy protection, ML model accuracy, and fostering trust are essential steps prior to clinical implementation. Future research should prioritize the establishment of comprehensive legal frameworks and regulatory mechanisms for using ML in MDD diagnosis while safeguarding patient privacy and rights. By doing so, we can advance accuracy and personalized care for MDD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103321"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of hospital-community-home collaborative health management on symptoms, cognition, anxiety, and depression in high-risk individuals for stroke.","authors":"Jing Wang, Chen-Xi Zhao, Jin Tian, Yan-Ru Li, Kai-Fang Ma, Rui Du, Meng-Kun Li, Rui Hu","doi":"10.5498/wjp.v15.i3.99152","DOIUrl":"10.5498/wjp.v15.i3.99152","url":null,"abstract":"<p><strong>Background: </strong>Effective health management for high-risk stroke populations is essential. The hospital-community-home (HCH) collaborative health management (CHM) model leverages resources from hospitals, communities, and families. By integrating patient information across these three domains, it facilitates the delivery of tailored guidance, health risk assessments, and three-in-one health education.</p><p><strong>Aim: </strong>To explore the effects of the HCH-CHM model on stroke risk reduction in high-risk populations.</p><p><strong>Methods: </strong>In total, 110 high-risk stroke patients screened in the community from January 2019 to January 2023 were enrolled, with 52 patients in the control group receiving routine health education and 58 in the observation group receiving HCH-CHM model interventions based on routine health education. Stroke awareness scores, health behavior levels, medication adherence, blood pressure, serum biochemical markers (systolic/diastolic blood pressure, total cholesterol, and triglyceride), and psychological measures (self-rating anxiety/depression scale) were evaluated and compared between groups.</p><p><strong>Results: </strong>The observation group showed statistically significant improvements in stroke awareness scores and health behavior levels compared to the control group (<i>P</i> < 0.05), with notable enhancements in lifestyle and dietary habits (<i>P</i> < 0.05) and reductions in postintervention systolic blood pressure, diastolic blood pressure, total cholesterol, triglyceride, self-rating anxiety scale, and self-rating depression scale scores (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The HCH-CHM model had a significant positive effect on high-risk stroke populations, effectively increasing disease awareness, improving health behavior and medication adherence, and appropriately ameliorating blood pressure, serum biochemical marker levels, and negative psychological symptoms.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99152"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}