World Journal of Psychiatry最新文献

{"title":"Relationship between weight-to-waist index and post-stroke depression.","authors":"Juan Li, Li-Jun Ma, Xiao-Yuan Ma, Bo Gao","doi":"10.5498/wjp.v15.i3.100909","DOIUrl":"10.5498/wjp.v15.i3.100909","url":null,"abstract":"<p><strong>Background: </strong>The weight-to-waist index (WWI) serves as an innovative metric specifically designed to assess central obesity. However, the relationship between WWI and the prevalence of post-stroke depression (PSD) remains inadequately explored in the literature.</p><p><strong>Aim: </strong>To elucidate the relationship between WWI and PSD.</p><p><strong>Methods: </strong>Data from the National Health and Nutrition Examination Survey 2005 to 2018 were analyzed. Multivariable logistic regression models and propensity score matching were utilized to investigate the association between WWI and PSD, with adjustments for potential confounders. The restricted cubic spline statistical method was applied to explore non-linear associations.</p><p><strong>Results: </strong>Participants with elevated WWI values had a significantly greater risk of developing PSD. Specifically, individuals in the higher WWI range exhibited more than twice the likelihood of developing PSD compared to those with lower WWI values (odds ratio = 2.21, 95% confidence interval: 1.84-2.66, <i>P</i> < 0.0001). After propensity score matching, the risk of PSD remained significantly elevated (odds ratio = 1.43, 95%confidence interval: 1.09-1.88, <i>P</i> = 0.01). Tertile analysis revealed that participants in the highest WWI tertile faced a significantly higher risk of PSD compared to those in the lowest tertile. Restricted cubic spline analysis further revealed a non-linear association, with the risk of PSD plateauing at higher WWI values.</p><p><strong>Conclusion: </strong>There is a significant association between elevated WWI and increased risk of PSD. Thus, regular depression screening should be implemented in stroke patients with elevated WWI to enhance patient outcomes.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100909"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the roles and applications of extracellular vesicles in depression.","authors":"Jing Wu, Jian Lu, Ming-Zhi Pan, Xiao-Chu Gu, Lu Dai, Yun Wang, Bin Shen, Xiao-Bin Zhang","doi":"10.5498/wjp.v15.i3.102643","DOIUrl":"10.5498/wjp.v15.i3.102643","url":null,"abstract":"<p><p>Depression is a prevalent mental disorder that affects numerous individuals, manifesting as persistent anhedonia, sadness, and hopelessness. Despite extensive research, the exact causes and optimal treatment approaches for depression remain unclear. Extracellular vesicles (EVs), which carry biological molecules such as proteins, lipids, nucleic acids, and metabolites, have emerged as crucial players in both pathological and physiological processes. EVs derived from various sources exert distinct effects on depression. Specifically, EVs released by neurons, astrocytes, microglia, oligodendrocytes, immune cells, stem cells, and even bacteria contribute to the pathogenesis of depression. Moreover, there is growing interest in potential of EVs as diagnostic and therapeutic tools for depression. This review provides a comprehensive overview of recent research on EVs from different sources, their roles in depression, and their potential clinical applications.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102643"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrative nursing as a holistic approach in modern healthcare: Integrating emotional and physical care.","authors":"Güzel Nur Yıldız, Bahar Çiftçi","doi":"10.5498/wjp.v15.i3.102956","DOIUrl":"10.5498/wjp.v15.i3.102956","url":null,"abstract":"<p><p>Narrative nursing (NN) is emerging as a critical approach in modern healthcare, addressing the complex interplay between psychological well-being and physical recovery. This manuscript discusses a study on NN and its role in alleviating psychological distress in patients with acute pancreatitis, published in the <i>World Journal of Psychiatry</i>. Their research demonstrates that NN, through structured storytelling, significantly reduces anxiety and depression, thereby enhancing patient satisfaction and fostering emotional resilience. This therapeutic approach extends beyond symptom management, offering a comprehensive strategy that supports the mental and emotional recovery of patients facing severe health challenges. NN provides a unique framework for engaging patients in their care journey, promoting a sense of agency, and strengthening the patient-provider relationship. In this manuscript, we explore the broader implications of NN by synthesizing findings from various studies, showing that NN is effective not only in acute settings but also in oncology, chronic illness management, and palliative care. The evidence indicates that integrating NN into standard clinical practice could enhance healthcare outcomes by addressing the holistic needs of patients, supporting psychological resilience, and fostering a compassionate healthcare environment.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102956"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating behavioral interventions for Tourette's syndrome: Current status and prospective.","authors":"Xiao-Man Chen, Shuo Zhang, Michael Xu","doi":"10.5498/wjp.v15.i3.99045","DOIUrl":"10.5498/wjp.v15.i3.99045","url":null,"abstract":"<p><p>In the evolving landscape of Tourette's syndrome (TS) treatment, behavioral therapies have emerged as essential to address the comorbid psychological issues, as well as motor and vocal tics. This editorial comments on the study by Wang <i>et al</i>, which showed that cognitive-behavioral therapy (CBT) combined with habit reversal training significantly improved anxiety and tic severity in children with TS. We highlight the current status and future perspectives of behavioral interventions such as CBT, and comprehensive behavioral intervention for tics, demonstrating their efficacy in alleviating TS symptoms and improving patients' quality of life. Recognizing the multifaceted nature of TS, our discussion integrates empirical evidence from various studies to provide a comprehensive perspective on the role of behavioral therapy in the management of this complex condition. This editorial concludes by emphasizing the need for innovative strategies that may address the limitations of existing treatments and advocates a multidisciplinary approach that combines behavioral, pharmacological, and neurobiological interventions to improve outcomes for patients with TS.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99045"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of suggestion therapy on mood and sleep quality in middle-aged women with depression.","authors":"Yuan Jiang, Ke-Ke Xia, Zhi-Yuan Lin","doi":"10.5498/wjp.v15.i3.100009","DOIUrl":"10.5498/wjp.v15.i3.100009","url":null,"abstract":"<p><strong>Background: </strong>Depression is one of the most common mental disorders, with high rates of disability, particularly among women.</p><p><strong>Aim: </strong>To explore the effects of suggestion therapy on anxiety, mood, and sleep-quality in middle-aged women with depression treated with escitalopram.</p><p><strong>Methods: </strong>Overall, 102 female patients with depression aged 35-49 years were divided into control and experimental groups. The control group received oral escitalopram therapy, starting at a dose of 5 mg/day, which was gradually increased to 10-20 mg/day after 1 week for a total of 8 weeks. The experimental group received the suggested therapy based on the control group. The Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), Profile of Mood States-Short Form, and Pittsburgh Sleep Quality Index (PSQI) were used to assess depression, anxiety, mood status, and sleep quality.</p><p><strong>Results: </strong>Before treatment, there were no significant differences in the SDS, SAS, Profile of Mood States, and PSQI scores between the two groups (<i>P</i> > 0.05). After treatment, compared to the control group and baseline, the SDS, SAS, tension-anxiety, depression-dejection, and confusion-bewilderment scores in the experimental group significantly decreased (<i>P</i> < 0.05), whereas sleep efficiency, sleep disturbance, hypnotics, and PSQI scores significantly increased (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Suggestion therapy combined with escitalopram treatment can reduce the severity of depression and anxiety, change mood status, and improve sleep quality in middle-aged women with depression.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100009"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a nomogram for postoperative delirium in elderly patients with hip fractures.","authors":"Liang Li, Wei-Wei Sheng, Li-Juan Song, Shuai Cheng, En-Gang Cui, Yong-Bing Zhang, Xue-Zhong Yu, Yan-Li Liu","doi":"10.5498/wjp.v15.i3.102117","DOIUrl":"10.5498/wjp.v15.i3.102117","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Postoperative delirium (POD) is a prevalent complication, particularly in elderly patients with hip fractures (HFs). It significantly affects recovery, length of hospital stay, healthcare costs, and long-term outcomes. Existing studies have investigated risk factors for POD, but most are limited by single-factor analyses or small sample sizes. This study systematically determines independent risk factors using large-scale data and machine learning techniques and develops a validated nomogram model to support early prediction and management of POD.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To investigate POD incidence in elderly patients with HF and the independent risk factors, according to which a nomogram prediction model was developed and validated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective study included elderly patients with HF who were surgically treated in Dongying People's Hospital from April 2018 to April 2022. The endpoint event includes POD. They were categorized into the modeling and validation cohorts in a 7:3 ratio by randomization. Both cohorts were further classified into the delirium and normal (non-delirium) groups according to the presence or absence of the endpoint event. The incidence of POD was calculated, and logistic multivariate analysis was conducted to determine the independent risk factors. The calibration curve and the Hosmer-Lemeshow test as well as the net benefit threshold probability interval by the decision curve were utilized to statistically validate the accuracy of the nomogram prediction model, developed according to each factor's influence intensity.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;This study included 532 elderly patients with HF, with an overall POD incidence of 14.85%. The comparison of baseline data with perioperative indicators revealed statistical differences in age (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), number of comorbidities (&lt;i&gt;P&lt;/i&gt; = 0.042), American Society of Anesthesiologists grading (&lt;i&gt;P&lt;/i&gt; = 0.004), preoperative red blood cell (RBC) count (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), preoperative albumin (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), preoperative hemoglobin (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), preoperative platelet count (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), intraoperative blood loss (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), RBC transfusion of ≥ 2 units (&lt;i&gt;P&lt;/i&gt; = 0.001), and postoperative intensive care unit care (&lt;i&gt;P&lt;/i&gt; &lt; 0.001) between the delirium and non-delirium groups. The participants were randomized to a training group (&lt;i&gt;n&lt;/i&gt; = 372) and a validation group (&lt;i&gt;n&lt;/i&gt; = 160). A score-risk nomogram prediction model was developed after screening key POD features using Lasso regression, support vector machine, and the random forest method. The nomogram showed excellent discriminatory capacity with area under the curve of 0.833 [95% confidence interval (CI) interval: 0.774-0.888] in the training group and 0.850 (95%CI: 0.718-0.982) in the validation group. Calibration curves demonstrated good agreement between predicted and actual probabilities, and decision curve a","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"102117"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic efficacy of transcranial direct current stimulation in treating auditory hallucinations in schizophrenia: A meta-analysis.","authors":"Shi-Jia Zou, Jin-Nan Shi","doi":"10.5498/wjp.v15.i3.99364","DOIUrl":"10.5498/wjp.v15.i3.99364","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia is a chronic psychiatric condition with complex symptomatology, including debilitating auditory hallucinations. Transcranial direct current stimulation (tDCS) has been explored as an adjunctive treatment to alleviate such symptoms.</p><p><strong>Aim: </strong>To evaluate the therapeutic efficacy of tDCS in schizophrenia.</p><p><strong>Methods: </strong>Adhering to PRISMA guidelines, we systematically searched PubMed, Embase, Web of Science, and the Cochrane Library on September 19, 2023, for randomized controlled trials examining the efficacy of tDCS in schizophrenia, with no language or time restrictions. We included studies that compared tDCS with a control condition and reported clinically relevant outcomes. Data extraction and quality assessments were performed by independent evaluators using the Cochrane Collaboration's risk of bias tool. Statistical heterogeneity was evaluated, and a random-effects model was applied due to moderate heterogeneity (<i>I</i> ² = 41.3%).</p><p><strong>Results: </strong>Nine studies comprising 425 participants (tDCS group: 219, control group: 206) were included. The meta-analysis demonstrated a significant reduction in auditory hallucination scores following tDCS treatment (weighted mean difference: -2.18, 95% confidence interval: -4.0 to -0.29, <i>P</i> < 0.01). Sensitivity analysis confirmed the robustness of the results, with no significant influence from individual studies. Additionally, publication bias was not detected, supporting the reliability and generalizability of the findings. These results underscore the efficacy of tDCS as a therapeutic intervention for auditory hallucinations in schizophrenia.</p><p><strong>Conclusion: </strong>tDCS significantly reduces auditory hallucinations in schizophrenia, suggesting its potential as an effective adjunctive treatment for managing this disabling symptom. The findings highlight the practical significance of tDCS in clinical settings, particularly for patients with treatment-resistant auditory hallucinations.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"99364"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibition of the microglial voltage-gated proton channel 1 channel ameliorates diabetes-associated cognitive dysfunction by regulating axon demyelination.","authors":"Chun-Yu Li, Shu-Jun Zhang, Jia-Lu Xu, Yan Yang, Zhi-Xuan Zeng, De-Lin Ma","doi":"10.5498/wjp.v15.i3.101178","DOIUrl":"10.5498/wjp.v15.i3.101178","url":null,"abstract":"<p><strong>Background: </strong>Diabetes is associated with increased cognitive decline and dementia due to the loss of myelinated nerve fiber function, which is linked to oligodendrocyte dysfunction. The voltage-gated proton channel 1 (Hv1) is important for the cellular proton extrusion machinery. However, its role in regulating diabetes-induced cognitive dysfunction is unclear.</p><p><strong>Aim: </strong>To investigate the role of Hv1 in cognitive impairment induced by diabetes and its potential mechanisms, focusing on neuroinflammation, oligodendrocyte apoptosis, and axonal demyelination.</p><p><strong>Methods: </strong>A diabetes model was established by administering a high-fat diet and streptozotocin injections in mice. Hv1 knockout (KO) and wild-type mice were used to evaluate cognitive function <i>via</i> behavioral tests and neuroinflammation using immunofluorescence. Oligodendrocyte apoptosis was assessed with the terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling assay, and axonal demyelination was analyzed using electron microscopy.</p><p><strong>Results: </strong>Hv1 expression was significantly increased in the corpus callosum of diabetic mice. Hv1 KO alleviated cognitive impairment, reduced oligodendrocyte apoptosis, and decreased the expression of inflammatory factors, including interleukin-1 and tumor necrosis factor-α, in diabetic mice. Electron microscopy revealed a reduction in myelin thickness and an increased g-ratio in diabetic mice, which were reversed by Hv1 KO.</p><p><strong>Conclusion: </strong>Hv1 plays a role in diabetes-induced cognitive dysfunction by modulating neuroinflammation and myelin integrity. Hv1 KO demonstrates therapeutic potential in mitigating diabetes-related cognitive decline and associated complications.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"101178"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mood symptoms, cognitive function, and changes of brain hemodynamics in patients with COVID-19: A functional near-infrared spectroscopy study.","authors":"Wen-Jin Ma, Ruo-Chao Yuan, Zi-Yu Peng, Qian Wu, Manal Al-Matary, Hui-Shu Yang, Peng Cheng, Guang-Ju Zhao, Chao-Chao Lu, Yue-Xin Zhang, Jia-Kun Hong, Wei-Hui Li","doi":"10.5498/wjp.v15.i3.100112","DOIUrl":"10.5498/wjp.v15.i3.100112","url":null,"abstract":"<p><strong>Background: </strong>Many patients with coronavirus disease 2019 (COVID-19) may experience emotional issues and cognitive impairment. However, it remains unclear whether the brain mediates the impact of COVID-19 on the emergence of psychopathological symptoms. It remains unclear whether anxiety and depression are caused by stressors or viral infection.</p><p><strong>Aim: </strong>To use functional near-infrared spectroscopy (fNIRS) to detect cortical hemodynamic changes in patients with COVID-19 and their relationship with mental symptoms (mainly depression and anxiety), to investigate whether COVID-19 causes these changes by affecting brain function.</p><p><strong>Methods: </strong>A total of 58 subjects, comprising 29 patients with first acute COVID-19 infection and 29 healthy controls without COVID-19 infection and without anxiety or depression were recruited. Then cortical activation during the performance of the verbal fluency test (VFT) and brain connectivity during the resting state (rs) were evaluated by 53-channel fNIRS. For the COVID-19-infected group, Patient Health Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) were used to assess the emotional state before fNIRS measures.</p><p><strong>Results: </strong>For the rs, compared to the uninfected group, the infected group exhibited lower rs functional connectivity (FC) in the dorsolateral prefrontal cortex (DLPFC), which was correlated with both the PHQ score and GAD score. During the VFT, the infected group exhibited significantly lower cortical activation than the uninfected group in both Broca-left and Broca-right. Besides, the integral value in the DLPFC-L showed a significant negative correlation with the PHQ-9 score during the VFT in the infected group.</p><p><strong>Conclusion: </strong>There were significant differences in the bilateral Broca area and DLPFC between the COVID-19-infected and uninfected groups, which may be the reason why COVID-19 infection impairs cognitive function and language function and leads to psychiatric symptoms. In addition, the rsFC in patients with COVID-19 was positively correlated with the severity of depression and anxiety, which may be related to the fact that the mental symptoms of patients with COVID-19 are characterized by depression and anxiety, rather than depression or anxiety alone. Our study provides evidence that the psychological and emotional issues caused by COVID-19 are not only due to external social factors but also involve more direct brain neural mechanisms and abnormal neural circuits, which also provide insights into the future treatment and prognosis of individuals with COVID-19.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"100112"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harmonizing the mind and body: The interrelationship between traditional Chinese medicine body constitution, mental health and sleep quality.","authors":"Juan-Juan Yang, Qian Wang, Wei Jiang","doi":"10.5498/wjp.v15.i3.103033","DOIUrl":"10.5498/wjp.v15.i3.103033","url":null,"abstract":"<p><strong>Background: </strong>Traditional Chinese medicine (TCM) body constitution is a key factor in determining and influencing the occurrence, development, and variation of diseases. As the mind interact with the body, TCM body constitution is useful in preventing and treating psychiatric disorders and insomnia.</p><p><strong>Aim: </strong>To investigate the interrelationship between TCM body constitution, psychiatric disorders and sleep quality.</p><p><strong>Methods: </strong>A total of 2441 participants were enrolled in our study. TCM body constitution was measured using the Constitution in Chinese Medicine Questionnaire, sleep quality was assessed using the Chinese version of the Pittsburgh Sleep Quality Index, and psychopathological symptoms were evaluated using Symptom Checklist-90. Logistic regression was used to estimate the interrelationship between TCM body constitution, psychiatric disorders and sleep quality.</p><p><strong>Results: </strong>The Pittsburgh Sleep Quality Index score and the proportions of participants with Qi-deficiency constitution, Qi-stagnation constitution, and blood-stasis constitution were significantly higher in the psychiatric symptoms group. Additionally, psychiatric symptoms were considerably associated with sleep quality, Qi-deficiency constitution, and Qi-stagnation constitution, but were inversely associated with male sex. Obsessive-compulsive symptoms were considerably associated with sleep quality, Qi-deficiency constitution and Qi-stagnation constitution. Depression was considerably associated with sleep quality, hyperuricemia, and Qi-stagnation constitution. Anxiety was considerably associated with sleep quality, diabetes, and Qi-stagnation constitution. Finally, poor sleep quality was considerably associated with Qi-deficiency constitution, Qi-stagnation constitution, dampness-heat constitution, phlegm-dampness constitution, and blood-stasis constitution but was inversely associated with male sex and body mass index > 23.9.</p><p><strong>Conclusion: </strong>TCM body constitutions are strongly associated with psychiatric symptoms and sleep quality. Further research is needed to verify whether TCM body constitution can be used to treat and prevent psychiatric conditions as well as enhance sleep quality.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 3","pages":"103033"},"PeriodicalIF":3.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}