World Journal of Psychiatry最新文献

{"title":"Mediating role of self-esteem in the relationship between parental disapproval of the child and alexithymic personality.","authors":"Elif Yöyen, Ali Rıfat Kılıç","doi":"10.5498/wjp.v15.i2.100135","DOIUrl":"10.5498/wjp.v15.i2.100135","url":null,"abstract":"<p><strong>Background: </strong>Alexithymia is defined as difficulties in identifying, expressing, and understanding emotions. An unapproving environment during childhood is defined as the child not receiving emotional approval from their parents, being punished, or having their emotions devalued. The formation of self-esteem is shaped by the influence of parental behavior during childhood. The communication that the child establishes with their parents contributes to their increased self-esteem and sense of importance. The absence of this may play a role in developmental psychopathology.</p><p><strong>Aim: </strong>To examine the mediating role of self-esteem in the relationship between a disapproving environment in childhood and alexithymia.</p><p><strong>Methods: </strong>The research in the relational screening model was conducted with 404 participants. Demographic Information Form, Disapproving Environment Scale in Childhood, Toronto Alexithymia Scale, and Rosenberg Self-Esteem Scale were used as data collection tools. Hayes' bootstrapping technique was used in the analysis of the data obtained from the research.</p><p><strong>Results: </strong>As a result of the analyses, parental disapproval positively predicted the level of alexithymia (<i>r_mother</i> = 0.51, <i>r_father</i> = 0.52, <i>P</i> < 0.05) and negatively predicted self-esteem (<i>r_mother</i> = -0.75, <i>r_father</i> = -0.67, <i>P</i> < 0.05). Additionally, self-esteem negatively predicted alexithymia (<i>r</i> = -0.58, <i>P</i> < 0.05). It was observed that self-esteem had a partial mediating effect on the relationship between parental disapproval and alexithymia. Family types were analyzed separately as chaotic, approving, perfect, and typical. Of these, the chaotic family type positively predicted alexithymia (<i>r</i> = 0.33, <i>P</i> < 0.05) and negatively predicted self-esteem (<i>r</i> = -0.60, <i>P</i> < 0.05). The approving family type negatively predicted alexithymia (<i>r</i> = -0.43, <i>P</i> < 0.05) and positively predicted self-esteem (<i>r</i> = 0.61, <i>P</i> < 0.05). The perfect family type negatively predicted alexithymia (<i>r</i> = -0.27, <i>P</i> < 0.05) and positively predicted self-esteem (<i>r</i> = -0.45, <i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The type of family in which the child grows up in and parental disapproval during childhood affected the child's self-esteem and caused alexithymic personality traits.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"100135"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression levels of the general public increases during the COVID-19 pandemic in China: A web-based cross-sectional survey.","authors":"Qin-Ming Qiu, Yu Xiao","doi":"10.5498/wjp.v15.i2.97971","DOIUrl":"10.5498/wjp.v15.i2.97971","url":null,"abstract":"<p><strong>Background: </strong>The coronavirus disease 2019 (COVID-19) outbreak lasted several months, having started in December 2019. This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.</p><p><strong>Aim: </strong>To investigate the depression levels of the general public in China during the COVID-19 pandemic.</p><p><strong>Methods: </strong>A total of 2001 self-reported questionnaires about Beck Depression Inventory (BDI) were collected on August 22, 2022 <i>via</i> the website. Each questionnaire included four levels of depression and other demographic information. The BDI scores and incidences of different depression levels were compared between various groups of respondents. <i>χ</i> ² analysis and the two-tailed <i>t</i>-test were used to assess categorical and continuous data, respectively. Multiple linear regressions and logistic regressions were employed for correlation analysis.</p><p><strong>Results: </strong>The averaged BDI score in this study was higher than that for the non-epidemic periods, as reported in previous studies. Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection, compared to the respondents who were not quarantined. The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer. Similarly, the people who did not return to work had higher BDI scores compared to those managed to. A significant association existed between the depression levels of the subgroups and each of the factors, except gender and location of residence. However, quarantine was the most relative predictor for depression levels, followed by failure to take preventive measures and losing a partner, either through divorce or death.</p><p><strong>Conclusion: </strong>Based on these data, psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic. Other countries can also use the data as a reference.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"97971"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and treatment of bipolar disorder in Phelan-McDermid syndrome: A case report and review of literature.","authors":"Yu-Yong Sun, Yong Xia, Qian-Na Zhi, Xiao-Yan Liu","doi":"10.5498/wjp.v15.i2.101948","DOIUrl":"10.5498/wjp.v15.i2.101948","url":null,"abstract":"<p><strong>Background: </strong>Phelan-McDermid syndrome (PMS) is a rare genetic disorder characterized by intellectual disability, delayed language development, autism spectrum disorders, motor tone abnormalities, and a high risk of psychiatric symptoms, including bipolar disorder.</p><p><strong>Case summary: </strong>This report presented an 18-year clinical history of a 36-year-old woman with PMS, marked by intellectual disabilities, social withdrawal, and stereotyped behaviors. Diagnosed with bipolar disorder at the age of 18 years old, she encountered significant treatment challenges, including severe adverse reactions to antipsychotic medications in 2022, which led to speech and functional regression. Through rehabilitation and comprehensive therapy, her condition gradually improved. In 2024, after further treatment, her symptoms stabilized, highlighting the complexities and successes of long-term management.</p><p><strong>Conclusion: </strong>Effective management of PMS requires a thorough clinical history, genetic testing, and long-term supportive care.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"101948"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative transcriptomic and proteomic analysis reveals that SERPING1 inhibits neuronal proliferation <i>via</i> the CaMKII-CREB-BDNF pathway in schizophrenia.","authors":"Feng Li, Xing Ren, Jia-Xiu Liu, Tian-Dao Wang, Bi Wang, Xiao-Bin Wei","doi":"10.5498/wjp.v15.i2.100214","DOIUrl":"10.5498/wjp.v15.i2.100214","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia (SZ), a chronic and widespread brain disorder, presents with complex etiology and pathogenesis that remain inadequately understood. Despite the absence of a universally recognized endophenotype, peripheral blood mononuclear cells (PBMCs) serve as a robust model for investigating intracellular alterations linked to SZ.</p><p><strong>Aim: </strong>To preliminarily investigate potential pathogenic mechanisms and identify novel biomarkers for SZ.</p><p><strong>Methods: </strong>PBMCs from SZ patients were subjected to integrative transcriptomic and proteomic analyses to uncover differentially expressed genes (DEGs) and differentially expressed proteins while mapping putative disease-associated signaling pathways. Key findings were validated using western blot (WB) and real-time fluorescence quantitative PCR (RT-qPCR). RNAi-lentivirus was employed to transfect rat hippocampal CA1 neurons in vitro, with subsequent verification of target gene expression <i>via</i> RT-qPCR. The levels of neuronal conduction proteins, including calmodulin-dependent protein kinase II (caMKII), CREB, and BDNF, were assessed through WB. Apoptosis was quantified by flow cytometry, while cell proliferation and viability were evaluated using the Cell Counting Kit-8 assay.</p><p><strong>Results: </strong>The integration of transcriptomic and proteomic analyses identified 6079 co-expressed genes, among which 25 DEGs were significantly altered between the SZ group and healthy controls. Notably, haptoglobin (<i>HP</i>), lactotransferrin (<i>LTF</i>), and <i>SERPING1</i> exhibited marked upregulation. KEGG pathway enrichment analysis implicated neuroactive ligand-receptor interaction pathways in disease pathogenesis. Clinical sample validation demonstrated elevated protein and mRNA levels of <i>HP</i>, <i>LTF</i>, and <i>SERPING1</i> in the SZ group compared to controls. WB analysis of all clinical samples further corroborated the significant upregulation of <i>SERPING1</i>. In hippocampal CA1 neurons transfected with lentivirus, reduced <i>SERPING1</i> expression was accompanied by increased levels of CaMKII, CREB, and BDNF, enhanced cell viability, and reduced apoptosis.</p><p><strong>Conclusion: </strong><i>SERPING1</i> may suppress neural cell proliferation in SZ patients <i>via</i> modulation of the CaMKII-CREB-BDNF signaling pathway.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"100214"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing interventions based on Snyder's hope theory for depression following percutaneous coronary interventions: A clinical study.","authors":"Xiao Wang, Hai-Feng Song, Si-Min Zhang","doi":"10.5498/wjp.v15.i2.99316","DOIUrl":"10.5498/wjp.v15.i2.99316","url":null,"abstract":"<p><strong>Background: </strong>Patients with depression following coronary heart disease often exhibit insufficient psychological resilience and self-care abilities; therefore, emphasis must be placed on nursing interventions.</p><p><strong>Aim: </strong>To analyze the application value of problem-oriented education combined with nursing interventions based on the Snyder hope theory model in depressed patients after percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>This study included 150 patients diagnosed with PCI postoperative depression because of coronary heart disease between February 2022 and February 2024. Participants were divided into two groups: A control group (<i>n</i> = 75) receiving problem-oriented education and an observation group (<i>n</i> = 75) receiving combined nursing interventions based on the Snyder hope theory model. Depression status, psychological resilience, self-care ability, and quality of life were compared between the two groups.</p><p><strong>Results: </strong>Before nursing interventions, there were no significant differences between the two groups (<i>P</i> > 0.05). After the interventions, depression scores decreased while psychological resilience, self-care ability, and quality of life scores increased significantly in the observation group compared to that in the control group, with statistically significant differences noted (<i>P</i> < 0.05). This combined approach can enhance psychological resilience, improve self-care abilities, and elevate the overall quality of life, warranting further promotion in clinical practice.</p><p><strong>Conclusion: </strong>Combination of problem-oriented education and nursing interventions based on the Snyder hope theory model effectively alleviates depression in patients following PCI for coronary heart disease.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"99316"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemispheric asymmetries and network dysfunctions in adolescent depression: A neuroimaging study using resting-state functional magnetic resonance imaging.","authors":"Ying Xiong, Ren-Qiang Yu, Xing-Yu Wang, Shun-Si Liang, Jie Ran, Xiao Li, Yi-Zhi Xu","doi":"10.5498/wjp.v15.i2.102412","DOIUrl":"10.5498/wjp.v15.i2.102412","url":null,"abstract":"<p><strong>Background: </strong>Currently, adolescent depression is one of the most significant public health concerns, markedly influencing emotional, cognitive, and social maturation. Despite advancements in distinguish the neurobiological substrates underlying depression, the intricate patterns of disrupted brain network connectivity in adolescents warrant further exploration.</p><p><strong>Aim: </strong>To elucidate the neural correlates of adolescent depression by examining brain network connectivity using resting-state functional magnetic resonance imaging (rs-fMRI).</p><p><strong>Methods: </strong>The study cohort comprised 74 depressed adolescents and 59 healthy controls aged 12 to 17 years. Participants underwent rs-fMRI to evaluate functional connectivity within and across critical brain networks, including the visual, default mode network (DMN), dorsal attention, salience, somatomotor, and frontoparietal control networks.</p><p><strong>Results: </strong>Analyses revealed pronounced functional disparities within key neural circuits among adolescents with depression. The results demonstrated existence of hemispheric asymmetries characterized by enhanced activity in the left visual network, which contrasted the diminished activity in the right hemisphere. The DMN facilitated increased activity within the left prefrontal cortex and reduced engagement in the right hemisphere, implicating disrupted self-referential and emotional processing mechanisms. Additionally, an overactive right dorsal attention network and a hypoactive salience network were identified, underscoring significant abnormalities in attentional and emotional regulation in adolescent depression.</p><p><strong>Conclusion: </strong>The findings from this study underscore distinct neural connectivity disruptions in adolescent depression, underscoring the critical role of specific neurobiological markers for precise early diagnosis of adolescent depression. The observed functional asymmetries and network-specific deviations elucidate the complex neurobiological architecture of adolescent depression, supporting the development of targeted therapeutic strategies.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"102412"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attribution of psychiatric manifestations to systemic lupus erythematosus in Chinese patients: A retrospective study.","authors":"Wen-Qi Geng, Xiao-Xi Yang, Jin-Ya Cao, Shang-Zhu Zhang, Yi-Nan Jiang, Jing Wei","doi":"10.5498/wjp.v15.i2.102247","DOIUrl":"10.5498/wjp.v15.i2.102247","url":null,"abstract":"<p><strong>Background: </strong>Not all neuropsychiatric (NP) manifestations in patients with systemic lupus erythematosus (SLE) are secondary to lupus. The clarification of the cause of NP symptoms influences therapeutic strategies for SLE.</p><p><strong>Aim: </strong>To understand the attribution of psychiatric manifestations in a cohort of Chinese patients with SLE.</p><p><strong>Methods: </strong>This retrospective single-center study analyzed 160 inpatient medical records. Clinical diagnosis, which is considered the gold standard, was used to divide the subjects into a psychiatric SLE (PSLE) group (G1) and a secondary psychiatric symptoms group (G2). Clinical features were compared between these two groups. The sensitivity and specificity of the Italian attribution model were explored.</p><p><strong>Results: </strong>A total of 171 psychiatric syndromes were recorded in 138 patients, including 87 cases of acute confusional state, 40 cases of cognitive dysfunction, 18 cases of psychosis, and 13 cases each of depressive disorder and mania or hypomania. A total of 141 (82.5%) syndromes were attributed to SLE. In contrast to G2 patients, G1 patients had higher SLE Disease Activity Index-2000 scores (21 <i>vs</i> 12, <i>P</i> = 0.001), a lower prevalence of anti-beta-2-glycoprotein 1 antibodies (8.6% <i>vs</i> 25.9%, <i>P</i> = 0.036), and a higher prevalence of anti-ribosomal ribonucleoprotein particle (rRNP) antibodies (39.0% <i>vs</i> 22.2%, <i>P</i> = 0.045). The Italian attribution model exhibited a sensitivity of 95.0% and a specificity of 70.0% when the threshold value was set at 7.</p><p><strong>Conclusion: </strong>Patients with PSLE exhibited increased disease activity. There is a correlation between PSLE and anti-rRNP antibodies. The Italian model effectively assesses multiple psychiatric manifestations in Chinese SLE patients who present with NP symptoms.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"102247"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of extended nursing based on self-efficacy theory on the anxiety of patients with intertrochanteric fracture.","authors":"You-Mei Yao, Xue-Yun Shao, Lin-Li Sha, Lin-Lin Qian","doi":"10.5498/wjp.v15.i2.100570","DOIUrl":"10.5498/wjp.v15.i2.100570","url":null,"abstract":"<p><strong>Background: </strong>Extended care based on self-efficacy theory to elderly patients with intertrochanteric fractures will provide data reference to optimize the care plan of these patients, reduce patients' concurrent mental diseases, and improve prognosis.</p><p><strong>Aim: </strong>To analyze the value of extended nursing based on the self-efficacy theory in older patients with intertrochanteric fractures.</p><p><strong>Methods: </strong>Older patients with intertrochanteric fractures (<i>n</i> = 88) admitted to our hospital between January 2021 and December 2024 were randomly divided into two groups - the control group (<i>n</i> = 44, routine nursing) and the observation group (<i>n</i> = 44, extended nursing) - <i>via</i> balloting and treated for 12 weeks. The mental state, pain severity, limb function, and self-nursing ability of all patients before and after nursing were analyzed.</p><p><strong>Results: </strong>After nursing, the Hamilton Anxiety Scale and General Self-Efficacy Scale scores of patients in the two groups improved. Notably, Hamilton Anxiety Scale and General Self-Efficacy Scale scores in the observation group were lower and higher, respectively, than those in the control group (<i>P</i> < 0.05). The pain severity in the observation group (2.64 ± 0.22) was lower than that in the control group (2.85 ± 0.41) (<i>P</i> < 0.05). The recovery rate of limb function was higher in the observation group than in the control group (<i>P</i> < 0.05). In addition, the self-nursing ability scores of the patients in both groups increased, with a significantly higher score in the observation group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Extended nursing based on the self-efficacy theory can significantly improve mental state, relieve pain, and promote the recovery of limb function and self-nursing ability in older patients with intertrochanteric fractures.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 2","pages":"100570"},"PeriodicalIF":3.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global research status and trends of somatic symptom disorder: A bibliometric study.","authors":"Chao Yang, Kun Zhang, Qian Wang, Shuai Wang, Huan Li, Kai Zhang","doi":"10.5498/wjp.v15.i1.100730","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.100730","url":null,"abstract":"<p><strong>Background: </strong>With the growing scholarly and clinical fascination with somatic symptom disorder (SSD), a bibliometric analysis is lacking.</p><p><strong>Aim: </strong>To conduct a bibliometric analysis to investigate the current status and frontiers of SSD.</p><p><strong>Methods: </strong>The documents related to SSD are obtained from the web of science core collection database (WoSCC), and VOSviewer 1.6.16 from January 1, 2000 to December 31, 2023, and the WoSCC's literature analysis wire were used to conduct the bibliometric analysis.</p><p><strong>Results: </strong>A total of 567 documents related to SSD were included, and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research, published in 277 journals. The most productive author, institution, country and journal were Löwe B, University of Hamburg, Germany, and <i>Journal of Psychosomatic Research</i> respectively. The first high-cited document was published in the <i>Journal of Psychosomatic Research</i> in 2013 by Dimsdale JE and colleagues, which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental disorders.</p><p><strong>Conclusion: </strong>In conclusion, the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria, functional impairment of SSD, and the treatment for SSD. More high-quality studies are needed to assess the diagnosis and treatment of SSD.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"100730"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures.","authors":"Bo Wang, Da Shi, Yin-Di Sun, Bo Dong","doi":"10.5498/wjp.v15.i1.101373","DOIUrl":"https://doi.org/10.5498/wjp.v15.i1.101373","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Traumatic injuries, such as falling, car accidents, and crushing mostly cause spinal fractures in young and middle-aged people, and &gt; 50% of them are thoracolumbar fractures. This kind of fracture is easily combined with serious injuries to peripheral nerves and soft tissues, which causes paralysis of the lower limbs if there is no timely rehabilitation treatment. Young patients with thoracolumbar fractures find it difficult to recover after the operation, and they are prone to depression, low self-esteem, and other negative emotions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To investigate the association between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures and the effect on rehabilitation outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study retrospectively analyzed 100 patients admitted to the orthopedic department of Honghui Hospital, Xi'an Jiaotong University who underwent thoracolumbar spine fracture surgery from January 2022 to June 2023. The general data of the patients were assessed with the Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD), life events scale, and social support rating scale (SSRS) to identify the correlation between anxiety, depression scores, and social stress and social support. The Japanese Orthopedic Association (JOA) was utilized to evaluate the rehabilitation outcomes of the patients and to analyze the effects of anxiety and depression scores on rehabilitation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;According to the scores of HAMD and HAMA in all patients, the prevalence of depression in patients was 39% (39/100), and the prevalence of anxiety was 49% (49/100). Patients were categorized into non-depression (&lt;i&gt;n&lt;/i&gt; = 61) and depression (&lt;i&gt;n&lt;/i&gt; = 39), non-anxiety (&lt;i&gt;n&lt;/i&gt; = 51), and anxiety (&lt;i&gt;n&lt;/i&gt; = 49) groups. Statistically significant differences in gender, occupation, Pittsburgh Sleep Quality Index (PSQI) score, and monthly family income were observed between the non-depression and depression groups (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). A significant difference in occupation and PSQI score was found between the non-anxiety and anxiety groups. Both depression (&lt;i&gt;r&lt;/i&gt; = 0.207, &lt;i&gt;P&lt;/i&gt; = 0.038) and anxiety scores (&lt;i&gt;r&lt;/i&gt; = 0.473, &lt;i&gt;P&lt;/i&gt; &lt; 0.001) were significantly and positively correlated with negative life events. The difference in negative life event scores as well as SSRS total and item scores was statistically significant between patients in the non-depression and depression groups (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). The difference between the non-anxiety and anxiety groups was statistically significant (&lt;i&gt;P&lt;/i&gt; &lt; 0.05) in the negative life event scores as well as the total SSRS scores. Additionally, JOA scores were significantly lower in both anxious and depressed patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Young patients with thoracolumbar fractures are prone to anxiety and depression. Patients' anxiety and depression are closely associated with social press","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 1","pages":"101373"},"PeriodicalIF":3.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}