World Journal of Psychiatry最新文献

{"title":"Interplay among bedtime procrastination, sleep patterns, and subjective wellbeing in the Indian population: An observational study.","authors":"Gunjan Parasher, Shikhar Gupta, Sujita Kumar Kar","doi":"10.5498/wjp.v15.i8.106092","DOIUrl":"10.5498/wjp.v15.i8.106092","url":null,"abstract":"<p><strong>Background: </strong>Sleep deprivation is a common problem in society, and bedtime procrastination (BtP) has become a significant cause of poor sleep among healthy individuals across various countries.</p><p><strong>Aim: </strong>To study BtP, sleep behavior, and subjective well-being in the Indian population.</p><p><strong>Methods: </strong>This was a cross-sectional study. The recruited participants were evaluated using the BtP Scale, World Health Organzation-5 Well-Being index, Patient Health Questionnaire-2, Generalized Anxiety Disorder 2-item, Munich Chronotype Questionnaire and Single-Item Sleep Quality Scale.</p><p><strong>Results: </strong>A total of 401 participants were recruited for the study. Symptoms of anxiety were higher in the female participants compared to males. Among females, there was a significant positive correlation between BtP score with symptoms of anxiety (<i>r</i> = 0.23) and depression (<i>r</i> = 0.15) and a negative correlation with subjective wellbeing (<i>r</i> = -0.23). A significant negative correlation was found between the ages of women and BtP score (<i>r</i> = -0.15). Among the male participants, there was a significant negative correlation of age with BtP score (<i>r</i> = -0.3) and anxiety (<i>r</i> = -0.19). Here, too, the BtP score was positively correlated with depression (<i>r</i> = 0.18) and anxiety (<i>r</i> = 0.35).</p><p><strong>Conclusion: </strong>BtP worsens anxiety, depression, sleep quality, and subjective well-being. It needs to be targeted for the promotion and prevention of mental health.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"106092"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptance and commitment therapy applied to early psychosis: Therapeutic foundations and a narrative systematic review.","authors":"Josep Pena-Garijo, Tábata Baeza-Mor, José Martinez-Raga","doi":"10.5498/wjp.v15.i8.107313","DOIUrl":"10.5498/wjp.v15.i8.107313","url":null,"abstract":"<p><strong>Background: </strong>Acceptance and commitment therapy (ACT) is a third-generation therapy that appears to be a promising psychological intervention for psychotic disorders. While several systematic reviews and meta-analyses that address the efficacy of ACT for psychosis have been conducted, no systematic review has specifically focused on the application of ACT to the early stages of psychosis.</p><p><strong>Aim: </strong>To review the state of the art regarding the feasibility and efficacy of treating early psychosis (EP) with ACT-based interventions.</p><p><strong>Methods: </strong>First, we describe the foundations of the ACT model to provide the background required to contextualize the main objective of this review. Second, we searched the PubMed and PsycINFO databases for studies published up to January 2025 and identified eight studies that met our selection criteria. The systematic review was conducted in accordance with the PRISMA guidelines and the critical appraisal checklist provided by the Joanna Briggs Institute for randomized controlled trials (RCTs).</p><p><strong>Results: </strong>All studies were published after 2019. Among the reviewed studies, five were RCTs with a total combined sample of 399 nonoverlapping participants. The methodological quality was moderate for RCTs. The results showed that ACT-based treatments are feasible and improve psychotic symptoms, medication adherence, and global functioning in patients with EP. Furthermore, preliminary evidence exists for the benefits of group-based and online-delivered programs and those that combine face-to-face therapy with novel real-time digital interventions, such as \"ecological momentary intervention\", to apply therapeutic concepts to real life.</p><p><strong>Conclusion: </strong>ACT-based treatments in the early stages of psychosis are feasible and improve symptoms, treatment adherence, and self-care skills. Although promising, these results are inconclusive. Further research is required.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"107313"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exosomal microRNAs in common mental disorders: Mechanisms, biomarker potential and therapeutic implications.","authors":"Ya-Nan He, Hao-Hao Zhu, Zhen-He Zhou, Kan-Kan Qu","doi":"10.5498/wjp.v15.i8.108933","DOIUrl":"10.5498/wjp.v15.i8.108933","url":null,"abstract":"<p><p>To illustrate the mechanisms of exosomal microRNAs (miRNAs) in common mental disorders, and explore their potential as diagnostic biomarkers and therapeutic targets, a systematic literature review of relevant studies on exosomal miRNAs in mental disorders was conducted. Data from cell experiments, animal models, and clinical studies were analyzed and combined to study the mechanisms and roles of exosomal miRNAs in various mental disorders. Research has shown that exosomal miRNAs, such as miR-146a, miR-223, miR-125b, and miR-451a, affect Alzheimer's disease (AD) formation by regulating key pathways such as toll-like receptor 4 (TLR4) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt), respectively. MiR-146a-5p regulates the occurrence of schizophrenia through the Notch pathway. TLR4 regulates miR-146a and miR-155 in major depressive disorder (MDD), and miR-144-5p regulates the disease through PI3K/Akt. Exosomal miR-484, miR-652-3p, miR-142-3p, miR-21a-3p, and miR-21-5p regulate key pathways in bipolar disorder, autism spectrum disorder, and Rett syndrome (<i>e.g</i>., TLR4, PI3K/Akt, and <i>Epha4</i>/<i>TEK</i>) and have an influence on mental disorders. Exosomal miRNAs are involved in the occurrence of mental disorders through TLR4, PI3K/Akt, and <i>Epha4</i>/<i>TEK</i> pathways, which provides a clearer understanding of disease cognition. Of these pathways, the TLR4 and PI3K/Akt pathways play a role in AD, MDD, and neurodevelopmental disorders, which can be used as an effective breakthrough in the study of mental disorders. Exosomal miRNAs could also serve as diagnostic biomarkers and therapeutic targets, providing new insights into precise interventions for mental disorders.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"108933"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health of older Asian Americans: Current issues, updates, and future directions.","authors":"Chiana Q Yang, Benjamin K P Woo","doi":"10.5498/wjp.v15.i8.106806","DOIUrl":"10.5498/wjp.v15.i8.106806","url":null,"abstract":"<p><p>As the population of older Asian Americans continues to grow rapidly, understanding their mental health needs has become increasingly critical. This literature review summarizes current issues, developments, and future directions in addressing the mental health challenges faced by older Asian Americans in the last five years. We briefly touch on the comparative prevalence of mental health disorders experienced by ethnic subgroups. Additionally, we review recent studies highlighting the role of the coronavirus disease 2019, racism, social support, cultural stigma, and self-rated health as significant factors influencing mental well-being of this population. We discuss the utilization of health services among older Asian Americans. We conclude with thoughts for future research, emphasizing the importance of longitudinal studies, consideration of diverse Asian American ethnic subgroups, and culturally sensitive diagnostic and treatment approaches.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"106806"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Startle response and its prepulse modification in health and under different psychopathologies: Could we find any specific patterns?","authors":"Zinaida I Storozheva","doi":"10.5498/wjp.v15.i8.107791","DOIUrl":"10.5498/wjp.v15.i8.107791","url":null,"abstract":"<p><p>The startle response (SR) is a generalized defensive response elicited by the presentation of a sudden intense stimulus. The presentation of a less intense signal (prepulse) before the central stimulus (pulse) affects the amplitude and latency of SR differently depending on the prepulse lead interval. The most studied form of such changes is prepulse inhibition (PPI), <i>i.e.</i> a decrease in SR amplitude at lead intervals of 50-500 ms. Prepulse facilitation, <i>i.e.</i> an increase in SR amplitude, can also be observed at lead intervals of 2000-4500 ms. The PPI deficiency has been found in a variety of psychopathologies and it has been suggested that it is a transdiagnostic phenomenon. However, some data from the literature support the existence of specific different nosologies, such as neurophysiological, neurochemical and molecular mechanisms that cause PPI lowering and affect prepulse facilitation of SR. This review provides a comparative analysis of studies on SR prepulse modification in healthy subjects and different groups of patients with mental or neurological disorders. The results of such an analysis may help to define directions for further research to improve methods of early diagnosis and to improve the validity of translational models.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"107791"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect tongue pressure feedback training with enabling education on swallowing and depression in head and neck tumor patients.","authors":"Jia-Mei Wang, Tai-Shan Tong","doi":"10.5498/wjp.v15.i8.106019","DOIUrl":"10.5498/wjp.v15.i8.106019","url":null,"abstract":"<p><strong>Background: </strong>Patients with head and neck cancer often develop depressive symptoms during radiochemotherapy due to changes in saliva secretion, radiation-induced oral mucositis, and dysphagia. These symptoms significantly affect quality of life. Although existing nursing interventions provide some relief, they have limitations in improving swallowing function and developing coping strategies.</p><p><strong>Aim: </strong>To evaluate the effectiveness of tongue pressure resistance feedback training combined with empowerment education in improving depressive symptoms and swallowing function in patients with head and neck cancer undergoing radiochemotherapy.</p><p><strong>Methods: </strong>This study included 110 patients with head and neck cancer who exhibited depressive symptoms and underwent radiochemotherapy at the Affiliated Hospital of Jiangnan University between January 2021 and December 2023. Patients were randomly assigned to either a reference group or an experimental group, each comprising 55 patients. The reference group received routine care, whereas the experimental group received tongue pressure resistance feedback training and empowerment education. After 6 weeks of continuous intervention, comparisons were made between the two groups regarding depressive symptom scores, swallowing function, coping strategies, and quality of life, both pre- and post-intervention.</p><p><strong>Results: </strong>Following the intervention, both groups demonstrated decreased scores for depressive symptoms and swallowing function, with the experimental group showing a significantly greater reduction than the reference group (<i>P</i> < 0.05). The experimental group also demonstrated higher confrontation scores and lower avoidance and submission scores for coping strategies than the reference group (<i>P</i> < 0.05). Quality of life scores improved in both groups after the intervention, with the experimental group showing markedly higher scores than the reference group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The combination of tongue pressure resistance feedback training and empowerment education is effective in alleviating depressive symptoms, enhancing swallowing function, optimizing coping strategies, and significantly improving the quality of life of patients with head and neck cancer undergoing radiochemotherapy. This approach shows promise for clinical applications and promotion.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"106019"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early diagnosis of bipolar disorder.","authors":"Peng Cui, Dong-Yu Han, Cheng-Hao Yang","doi":"10.5498/wjp.v15.i8.106125","DOIUrl":"10.5498/wjp.v15.i8.106125","url":null,"abstract":"<p><p>Bipolar disorder (BD) is a severe mood disorder characterized by recurrent episodes of mania and depression, and it is prone to delayed diagnosis, which can lead to worsened outcomes, including more frequent mood episodes, greater functional impairment, and comorbidities. Early diagnosis of BD remains a significant challenge, although recent advances offer promising insights, such as research in molecular biomarkers, neuroimaging, exosomes, genetics, and epigenetics. This mini-review highlights their potential for providing earlier, more accurate identification of BD and discusses the underlying reasons why current research has not yet succeeded. For instance, the high heterogeneity of symptomatic presentations leads to low consistency in study participants; delayed BD diagnosis results in the inclusion of potential BD patients in the depression group; low specificity of biomarkers stems from limited understanding of BD pathophysiology; and there is a possibility that BD is not innate but develops over the course of the disease. Deepening our understanding of BD pathology, identifying more specific biomarkers, and integrating multiomics approaches for validation studies in well-defined homogeneous cohorts hold promise for significant breakthroughs.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"106125"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of preoperative psychological stress on selected parameters in older patients undergoing total hip arthroplasty.","authors":"Jing-Jing Cao, Chuan-Lei Yin, Xiao-Mei Li, Xiao-Juan Sha, Liang Li, Cheng-Yong Sun, Li-Li Zhang","doi":"10.5498/wjp.v15.i8.103302","DOIUrl":"10.5498/wjp.v15.i8.103302","url":null,"abstract":"<p><strong>Background: </strong>Total hip arthroplasty (THA) is an increasingly common treatment for older patients with hip osteoarthritis. Psychological stress is common before THA, although its clinical effects on selected parameters such as joint function, quality of life, and postoperative complications remain unclear.</p><p><strong>Aim: </strong>To investigate the effects of preoperative psychological stress on selected parameters in older patients who underwent THA.</p><p><strong>Methods: </strong>Ninety older patients who underwent THA between January 2023 and August 2024 were divided into two groups by their preoperative self-rated anxiety scale and self-rated depression scale scores, including high-stress (<i>n</i> = 42) and low-stress (<i>n</i> = 48). The postoperative joint function, short form-36 health survey (SF-36) score, incidence of postoperative complications, and other indicators were compared between the two groups. Pearson's correlation coefficient analysis of the relationship among preoperative psychological stress, quality of life, and postoperative complications was performed.</p><p><strong>Results: </strong>Postoperative joint function and quality of life were lower in the high-stress group than they were in the low-stress group (<i>P</i> < 0.05). The incidence of postoperative complications was higher in the high-stress group (29.27%) than it was in the low-stress group (9.30%) (<i>P</i> < 0.05). Correlation analysis revealed that psychological stress was correlated with the Harris hip and SF-36 scores. Total scores on the scale, including physical function, physical pain, general health, mental health, social function, vitality, and emotional function, were negatively correlated (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Preoperative psychological stress results in adverse effects on quality of life and complications in older patients undergoing THA. Therefore, pre-operative psychological interventions should be strengthened to improve post-operative outcomes.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 8","pages":"103302"},"PeriodicalIF":3.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of depressive symptoms in postmenopausal women with osteoporosis, specialized psychological nursing intervention measures, and key point analysis.","authors":"Qiu-Mei Cui, Yu-Fang Su","doi":"10.5498/wjp.v15.i7.104974","DOIUrl":"10.5498/wjp.v15.i7.104974","url":null,"abstract":"<p><strong>Background: </strong>Postmenopausal women with osteoporosis are at high risk of developing depressive symptoms, necessitating specialized psychological nursing interventions.</p><p><strong>Aim: </strong>To investigate factors influencing depressive symptoms in postmenopausal women with osteoporosis and develop targeted psychological nursing interventions.</p><p><strong>Methods: </strong>A total of 180 postmenopausal women with osteoporosis admitted to the Department of Orthopedics at the First Affiliated Hospital of Soochow University between October 2021 and October 2024 were selected as research participants. Information on age, duration of menopause, body mass index, education level, marital status, activity intensity, bone density, presence of chronic diseases, calcium supplement intake, sex hormone levels, and depressive symptoms were collected. The 24-item Hamilton Depression Scale was used for assessment.</p><p><strong>Results: </strong>Forty-eight patients had no depressive symptoms, and 132 patients had depressive symptoms. Comprehensive univariate and multivariate logistic regression analyses showed that low bone density in the lumbar spine (L2-L4) and femoral neck, presence of chronic diseases, and low 5-hydroxytryptamine levels were independent risk factors for depressive symptoms, whereas calcium supplement intake and moderate to high-intensity activity were independent protective factors.</p><p><strong>Conclusion: </strong>By implementing specialized psychological nursing interventions, and providing rehabilitation guidance, the incidence of depressive symptoms can be effectively reduced, improving the psychological health status and patient quality of life.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 7","pages":"104974"},"PeriodicalIF":3.4,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging and neuroelectrophysiological features of music's effects on anhedonia in major depressive disorder: A minireview.","authors":"Yi-Fan Sun, Qi Zhang, Jun Wang, Zhen-He Zhou","doi":"10.5498/wjp.v15.i7.107721","DOIUrl":"10.5498/wjp.v15.i7.107721","url":null,"abstract":"<p><p>Major depressive disorder (MDD), one of the most prevalent mental illnesses, is characterized by anhedonia, the inability to experience pleasure from rewarding activities. This minireview examines the complex relationship between music, anhedonia, and neural activity from neuroimaging and neuroelectrophysiological perspectives. It synthesizes the latest advances in music neuroscience, exploring music's potential to modulate emotional responses and alleviate anhedonia in depressed individuals. Anhedonia has been linked to dysfunctional brain reward circuits. Functional magnetic resonance imaging studies have revealed that the potential mechanism by which music exerts its anti-depressive effect may involve the reactivation of the anterior cingulate cortex, while electroencephalographic studies have revealed that oscillatory network dysfunction significantly impairs music perception engagement in patients with MDD. Musical chills, representing intense emotional peaks during musical experiences, can evoke profound pleasure in healthy individuals and may offer a therapeutic modality for alleviating anhedonia in MDD. This review discusses how music therapy may support emotional regulation by activating these neural pathways and enhancing affective processing. Despite promising developments, this field remains understudied. A more nuanced research approach is urgently needed to better understand the mechanisms underlying music's effects on anhedonia and to develop effective interventions.</p>","PeriodicalId":23896,"journal":{"name":"World Journal of Psychiatry","volume":"15 7","pages":"107721"},"PeriodicalIF":3.4,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}