Wiener Klinische Wochenschrift最新文献

{"title":"Excessive smartphone use increases self-reported auditory and vestibular symptoms.","authors":"Emre Söylemez, Mehmet Dağ, Abdulkadir Ilgaz, Bekir Korkmaz, Ümit Topçuoğlu, Ahmet Düha Koç, Serdar Ensari","doi":"10.1007/s00508-024-02418-1","DOIUrl":"10.1007/s00508-024-02418-1","url":null,"abstract":"<p><strong>Background: </strong>With widespread smartphone use, there is growing concern about their potential impact on human health.</p><p><strong>Objective: </strong>The effects of smartphone use on self-reported hearing ability, tinnitus, balance, falls, and anxiety level were investigated in this study.</p><p><strong>Methods: </strong>This study included 682 participants who were divided into 2 groups: a high smartphone use (HSU) group and a low smartphone use (LSU) group. Both groups were evaluated for hearing ability using the Amsterdam inventory for auditory disability and handicap; balance status using the vertigo, dizziness, imbalance symptom scale; anxiety status using the Beck anxiety index; and fall and tinnitus status using the visual analog scale.</p><p><strong>Results: </strong>The HSU group showed significantly worse hearing ability, tinnitus, balance, falling, and anxiety status results than the LSU group (p < 0.001). There was a positive correlation between smartphone addiction severity and auditory impairment, tinnitus, risk of falling, and anxiety, as well as a negative correlation with balance score (p < 0.001).</p><p><strong>Conclusion: </strong>The findings suggest that individuals with excessive smartphone use are more likely to experience hearing, tinnitus, balance, falling, and anxiety problems than those who use smartphones less frequently. Excessive smartphone use may be considered a potential risk factor for these problems.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"520-526"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S100 as marker for immune effector cell-associated neurotoxicity syndrome.","authors":"Axel Schulenburg, Lina Z Rüsing, Armin Bumberger, Margit Mitterbauer, Werner Rabitsch","doi":"10.1007/s00508-024-02451-0","DOIUrl":"10.1007/s00508-024-02451-0","url":null,"abstract":"<p><p>Chimeric antigen receptor (CAR)-T cell therapy is a new and successful treatment for otherwise refractory malignancies but despite the growing number of applications, this form of treatment is still associated with significant toxicity. Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) in particular are common and dangerous side effects. This report is about two patients who received CAR‑T cell therapy and subsequently developed ICANS. This was successfully treated. During CAR‑T cell therapy, a blood marker, S100, was monitored daily. It correlated with the occurrence and progression of ICANS.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"517-519"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MUW researcher of the month.","authors":"","doi":"10.1007/s00508-025-02589-5","DOIUrl":"https://doi.org/10.1007/s00508-025-02589-5","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 15-16","pages":"532-533"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of low-level laser therapy on symptomatic calcific rotator cuff tendinopathy : A prospective randomized controlled study.","authors":"Yasemin Tombak, Ozgur Zeliha Karaahmet, Aysegul Tombak, Eda Gurcay","doi":"10.1007/s00508-024-02437-y","DOIUrl":"10.1007/s00508-024-02437-y","url":null,"abstract":"<p><strong>Objective: </strong>Rotator cuff calcific tendinitis (RCCT) is a benign but incapacitating condition and in some patients it is the cause of chronic debilitating pain and functional disability. We aimed to reveal the short-term effects of low-level laser therapy (LLLT) on clinical and sonographic parameters in patients with symptomatic RCCT.</p><p><strong>Method: </strong>This prospective randomized controlled study analyzed 76 painful shoulders of 68 patients aged 18-75 years, with over 3 months of shoulder pain and where RCCT was confirmed sonographically. Patients in the LLLT group (received 5 LLLT sessions per week and home exercises for 5 days/week for 3 weeks) and the control group (received home exercises, 5 days/week for 3 weeks) were assessed clinically and sonographically just before and after treatment, recording pain intensity, range of motion (ROM), shoulder functional status, location (supraspinatus/infraspinatus, subscapularis), number and degree of calcification. Degree of calcification was determined with ultrasound and classified by the Bianchi-Martinoli classification. The LLLT was applied to the calcified areas marked under ultrasound guidance.</p><p><strong>Results: </strong>Both groups showed statistically significant improvements in ROM, pain intensity, shoulder pain and disability index (SPADI) pain/disability/total, and degree of calcification after treatment. No significant change was achieved for calcification in the control group. Considering the change values, improvements in abduction, extension, pain intensity, SPADI pain/disability/total, calcification number, and calcification degree parameters were found to be statistically significantly better in the LLLT group than in the control group.</p><p><strong>Conclusion: </strong>Adding LLLT to the home program in treatment of symptomatic RCCT outperformed the home program alone, reducing the number and severity of calcifications, improving pain and disability.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"479-486"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal function and pain outcomes following segmental resection or discoid resection for low rectal endometriosis.","authors":"Ezgi Darici, Attila Bokor, Dominika Miklos, Daria Pashkunova, Anna Rath, Gernot Hudelist","doi":"10.1007/s00508-024-02448-9","DOIUrl":"10.1007/s00508-024-02448-9","url":null,"abstract":"<p><strong>Introduction: </strong>This study aims to examine the effect of full thickness discoid resection (FTDR) and modified, limited nerve-vessel sparing segmental bowel resection (NVSSR) in symptomatic patients with low rectal deep endometriosis (DE) within 7 cm from the anal verge.  Presurgical and postsurgical evaluation of gastrointestinal (GI) function reflected by low anterior resection syndrome (LARS) and gastrointestinal function-related quality of life index (GIQLI) scores, complication rates, pain scores/visual analog scale (VAS) and endometriosis health profile (EHP-30) was performed.</p><p><strong>Methods: </strong>In this prospective multicenter cohort study, 63 premenopausal patients with symptomatic low (within 7 cm from the anal verge) colorectal endometriosis, undergoing low modified limited nerve vessel sparing rectal segmental bowel resection (NVSSR) and full thickness discoid resection (FTDR) were evaluated. Presurgery and postsurgery lower anterior resection syndrome (LARS) scores, gastrointestinal function-related quality of life index (GIQLI), pain symptoms, endometriosis health profile (EHP-30) parameters compared between two groups.</p><p><strong>Results: </strong>Out of 63 women, 49 (77.8%) underwent NVSSR while 14 (22.2%) underwent FTDR. LARS-like symptoms were observed presurgically in 24/63 (38.1%) patients. Postsurgical LARS was observed in 14/63 (22.2%) of the patients (10/49, 20.4% in NVSSR vs. 4/14, 28.5% in the FTDR group). The LARS-like symptoms significantly decreased following surgery in the FTDR group (p = 0.049) and showed a trend for decrease in the NVSSR group (p = 0.077). Postsurgical de novo LARS was only observed in 5/63 (8%) of the patients (NVSSR 4/49, 8.1%, FTDR 1/14, 7.1%). Postsurgical GIQLI scores improved in both groups (p < 0.001) with comparable changes in the NVSSR and FTDR cohorts (p = 0.490). Postoperative grade III complication rates between NVSSR and FTDR did not vary significantly (6/49, 12.2% vs. 3/14, 21.4% p = 0.26). Pain/VAS scores and EHP-30 scores significantly decreased after a mean follow-up of 29.6 ± 11 months and 30.6 ± 11 months in the NVSSR and FTDR groups, respectively (EHP-30; p < 0.001; dysmenorrhea, dyspareunia, dyschezia all p < 0.05 for both cohorts).</p><p><strong>Discussion: </strong>When comparing low colorectal surgery by either NVSSR or FTDR in a high-risk group for surgical complications, both techniques confer improvement of GI function reflected by LARS and GIQLI with non-significant differences in major complication rates, reduced pain and EHP-30 scores.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"495-503"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Konsensuspapier der Österreichischen Adipositasgesellschaft (ÖAG).","authors":"J M Brix","doi":"10.1007/s00508-025-02568-w","DOIUrl":"https://doi.org/10.1007/s00508-025-02568-w","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 Suppl 5","pages":"167-217"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic equality in initiation of biologic treatment in Danish patients with inflammatory bowel disease.","authors":"Sofie Ronja Petersen, Nathalie Fogh Rasmussen, Agnete Overgaard Donskov, Lau Caspar Thygesen, Kim Rose Olsen, Linda Juel Ahrenfeldt, Vibeke Andersen","doi":"10.1007/s00508-024-02376-8","DOIUrl":"10.1007/s00508-024-02376-8","url":null,"abstract":"<p><strong>Background: </strong>Low socioeconomic status is associated with disadvantages in health outcomes and delivery of medical care in patients with Inflammatory Bowel Disease (IBD). Inequality in the utilisation of biologic treatment is largely unexplored.</p><p><strong>Aim: </strong>To explore the potential association of socioeconomic status and time to first biologic treatment in a population-based IBD cohort.</p><p><strong>Methods: </strong>All 37,380 IBD incidences between 2000 and 2017 from the Danish National Patient Register were identified and linked to socioeconomic information including educational level, income and occupational status at diagnosis. Hazard ratios for receiving biologic treatment among socioeconomic groups were estimated using Cox proportional hazard regression.</p><p><strong>Results: </strong>No difference in time between diagnosis and biologic treatment initiation was found comparing patients with upper secondary, vocational, or academic education to those with lower secondary education in patients with IBD. Patients with Crohn's disease in the two highest income quartiles received biologic treatment earlier (HR 1.16; 95% CI: 1.04; 1.30 & HR 1.15; 95% CI: 1.03; 1.30). An elevated treatment rate was found for persons with \"other\" occupational status (unspecified source of income) compared to employed persons in patients with ulcerative colitis (HR 1.36; 95% CI: 1.11; 1.66), but not in patients with Crohn's disease.</p><p><strong>Conclusion: </strong>This study revealed equal initiation of biologic treatment among patients with IBD across different educational background, income and occupational status. However, results are limited to a setting with free universal healthcare coverage and treatment needs should be considered and addressed in future research.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"463-469"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MUW researcher of the month.","authors":"","doi":"10.1007/s00508-025-02588-6","DOIUrl":"https://doi.org/10.1007/s00508-025-02588-6","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 15-16","pages":"530-531"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone use-related acute accommodative esotropia : A possible new paradigm of visual disorders associated with the use of modern technologies.","authors":"Ines Mlinarevic Polic, Darko Katalinic, Ivan Aleric, Renato Pejic, Ivana Skrlec, Jasminka Talapko, Igor Zabic, Aleksandar Vcev","doi":"10.1007/s00508-025-02502-0","DOIUrl":"10.1007/s00508-025-02502-0","url":null,"abstract":"<p><p>We present a rare case of a 9-year-old child with acute accommodative comitant esotropia, a form of acquired strabismus caused by excessive smartphone use. Symptoms commonly include double vision, closing or covering one eye when working at close range and tilting the head or its unnatural position to correct visual abnormalities; however, there are also patients without any symptoms. As part of the differential diagnosis it is necessary to exclude any eye diseases or refractive errors and it is highly recommended to carefully exclude pathologies of the central nervous system and intracranial disorders. In absolute numbers seen so far in real life, acute accommodative comitant esotropia is still a rare phenomenon and the relation to smartphone use might be suspected only after all other etiologies have been excluded. Acute accommodative comitant esotropia is mostly a temporary disorder and corrective glasses are usually sufficient for treatment. The present case demonstrates that forming a completely new type of visual disorder related to modern technologies is possible, even in age groups of children where this is a rare occurrence.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"527-529"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective, randomized study on the effects of autologous concentrated growth factors in the treatment of cystic lesions of the jaw.","authors":"Christoph Sacher, Daniel Holzinger, Florian Wagner, Moritz Bechtold, Robert Pillerstorf, Simon Bigus","doi":"10.1007/s00508-025-02567-x","DOIUrl":"https://doi.org/10.1007/s00508-025-02567-x","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to investigate the efficacy of autologous concentrated growth factors (aCGF) in the treatment and healing of cystic lesions of the jaw.</p><p><strong>Material and methods: </strong>In this prospective randomized intervention study 138 patients were enrolled, with 68 patients undergoing cystectomy alone and 70 patients undergoing cystectomy with defect filling using autologous concentrated growth factors. Bone healing was volumetrically measured using cone beam computed tomography (CBCT) at 6 and 12 months postoperatively. Clinical follow-ups were conducted 14 days, 1 month, 3 months, 6 months, and 12 months after the treatment.</p><p><strong>Results: </strong>In both groups, almost complete bone healing occurred, with no significant differences observed between the two groups (P =0.484). In the aCGF group there was a trend towards a reduction in wound healing disturbances after 14 days, although this reduction was not statistically significant (P =0.071).</p><p><strong>Conclusion: </strong>The use of aCGF following cystectomy does not show radiologically measurable significantly improved bone healing; however, a tendency towards improved wound healing compared to cystectomy without any filling materials could be observed in the initial healing period.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}