Wiener Klinische Wochenschrift最新文献

{"title":"Epidemiology of suicide among Austrian children and adolescents: 2015-2024.","authors":"Madeleine Jaeger, Benedikt Till, Kanita Dervic, Paul L Plener, Zrinka Laido, Thomas Niederkrotenthaler","doi":"10.1007/s00508-026-02787-9","DOIUrl":"https://doi.org/10.1007/s00508-026-02787-9","url":null,"abstract":"<p><strong>Background: </strong>Mental health among young people and suicidality are major ongoing public health issues. This study aims to provide updated epidemiological information on youth suicides in Austria.</p><p><strong>Methods: </strong>Suicide and population data for 10-19-year-olds were obtained from Statistics Austria. We examined the distribution of suicide methods, age, sex and regional differences, as well as monthly distribution of suicides for the period 2015-2024. In addition, we calculated trends in youth suicides using annual suicide rates for boys and girls between 2005 and 2024 and assessed if the pandemic year (2020) resulted in changes in suicide rates.</p><p><strong>Results: </strong>A total of 302 youth suicides (29.5% girls) were registered between 2015 and 2024, corresponding to an overall suicide rate of 3.4 per 100,000 individuals (boys 4.7/100,000, girls 2.1/100,000; male-female ratio 2.2:1). Total suicide rate of 10-14-year-olds was 0.6/100,000 children, and total suicide rate of 15-19-year-olds was 6.1/100,000 adolescents. Hanging was the most frequent method in both sexes, followed by jumping or lying before a moving object and jumping from a high place. Significant regional differences regarding suicide rate were found. Furthermore, downward time trends were observed between 2005 and 2024 for overall suicide rates and suicide rates among boys but there was a trend towards an increase at the onset of the pandemic in 2020.</p><p><strong>Conclusion: </strong>Youth suicide rates in Austria continued to decline in the time period 2005-2024, but COVID-19 marked a trend towards an increase in suicide rates. The present findings are relevant to provide information on ongoing discussions on youth suicide.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraceptive behavior and education among adolescents in Tyrol.","authors":"Bettina Böttcher, Valentina Schatzl, Mirjam Gahl, Coco Toth, David Riedl, Elisabeth Reiser, Bettina Toth","doi":"10.1007/s00508-026-02702-2","DOIUrl":"10.1007/s00508-026-02702-2","url":null,"abstract":"<p><strong>Background: </strong>Evidence on adolescents' contraceptive use and education in Austria remains limited. We aimed to describe contraceptive behavior, satisfaction with methods and sources/content of contraceptive education among pupils in Tyrol and to explore correlates of any contraceptive use among sexually active adolescents.</p><p><strong>Methods: </strong>Cross-sectional online survey (April-July 2022) of pupils aged 14-18 years (N = 369) recruited via schools. Prespecified outcomes included current method use (stratified by sexual activity), satisfaction ratings and education sources. Analyses comprised descriptive statistics, χ²/ANOVA as appropriate, and multivariable logistic regression among sexually active participants with covariates (age, sex, school type).</p><p><strong>Results: </strong>Overall, 91 (24.7%) pupils reported prior intercourse (median age at first intercourse 15 years); among sexually active adolescents, condoms (N = 64, 64%) and the pill (N = 37, 36%) predominated, while method non-use remained common (72%). Satisfaction varied by method; affordability scored lowest. Although > 90% reported prior education, 55% requested more information; condoms and the pill were most frequently covered. In adjusted models, any contraceptive use among sexually active adolescents was positively associated with older age and prior counselling.</p><p><strong>Conclusion: </strong>In this exploratory sample adolescents report mixed contraceptive use and a sustained demand for tailored information. The findings highlight the need to evaluate counselling quality and affordability in the future. Causal inferences and policy projections are beyond the scope of these data.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"455-461"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fortbildungen der Österreichischen Gesellschaft für Pneumologie.","authors":"","doi":"10.1007/s00508-026-02807-8","DOIUrl":"https://doi.org/10.1007/s00508-026-02807-8","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"138 15-16","pages":"515"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevention of venous thromboembolism in orthopaedics and traumatology: Austrian interdisciplinary consensus statement 2026].","authors":"Michael Humenberger, Sibylle Langenecker, Anna Antoni, Cihan Ay, Herbert Bachler, Gabriella Cerna-Stadlmann, Thomas Feurstein, Alexander Haushofer, Florian Prüller, Eva Schaden, Fabian Schmid, Rene El Attal, Vinzenz Auersperg","doi":"10.1007/s00508-026-02781-1","DOIUrl":"10.1007/s00508-026-02781-1","url":null,"abstract":"<p><p>Venous thromboembolism (VTE), a disease entity comprising deep vein thrombosis (DVT) and/or pulmonary embolism (PE), represents one of the most frequent and potentially life-threatening complications in orthopaedics and traumatology [1]. The previous Austrian recommendation on VTE prophylaxis in musculoskeletal procedures, dating from 2014 [2], no longer adequately reflects current evidence-based pharmacological and nonpharmacological strategies. Current international interdisciplinary guidelines on VTE prophylaxis, such as those issued by the European Society of Anaesthesiology and Intensive Care (ESAIC) [3] and the Association of the Scientific Medical Societies in Germany (AWMF) [4], were therefore adapted with consideration of Austrian healthcare structures. In particular, clearly defined criteria for a functional early mobilisation concept within the framework of a fast-track programme, as well as structured recommendations on VTE prophylaxis in conservative orthopaedic and traumatological treatments, have been lacking to date. To develop practice-oriented, evidence-based recommendations, an interdisciplinary consensus group comprising representatives of the Austrian medical societies relevant to this topic was convened. The aim was to formulate more structured, risk-adapted recommendations that take the Austrian healthcare context into account.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"791-803"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13481471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining MELD-XI score and hemodynamic parameters enhances short-term prognostic value in patients undergoing transcatheter tricuspid valve interventions.","authors":"Johannes Schlegl, Marwin Bannehr, Tanja Kücken, Michael Lichtenauer, Alexander Krutz, Vera Paar, Michael Neuß, Anja Haase-Fielitz, Christian Butter, Christoph Edlinger","doi":"10.1007/s00508-025-02690-9","DOIUrl":"10.1007/s00508-025-02690-9","url":null,"abstract":"<p><strong>Background: </strong>Hepatorenal dysfunction is a key prognostic factor in patients with symptomatic tricuspid valve regurgitation (TR). This study evaluated the prognostic value of hepatorenal dysfunction using the Model for End-stage Liver Disease (MELD), the modified MELD-XI score, and right heart hemodynamic parameters in patients undergoing transcatheter tricuspid valve interventions (TTVI).</p><p><strong>Methods: </strong>This prospective, single-center cohort study included patients undergoing edge-to-edge or heterotopic tricuspid valve repair. The MELD and MELD-XI scores were calculated using creatinine, bilirubin and the international normalized ratio (INR). All patients underwent right heart catheterization. The predictive value of MELD/MELD-XI scores and hemodynamic parameters, individually and combined, was assessed for a composite endpoint of 3‑month mortality or rehospitalization using receiver operating characteristics (ROC) analysis.</p><p><strong>Results: </strong>In this study 36 patients (mean age 80.2 ± 5.9 years; 33.3% male) were analyzed. Rehospitalization occurred in 25% and the 3‑month mortality was 11%. Both MELD-XI (area under the curve, AUC 0.96, 95% confidence interval, CI 0.88-1.00, p = 0.01) and MELD score (AUC 0.91, 95% CI 0.78-1.00, p = 0.023) showed excellent predictive values for mortality. The preinterventional MELD-XI score, right ventricular (RV) pressure (AUC 0.82, 95% CI 0.61-1.00, p = 0.029), right atrial (RA) pressure (AUC 0.86, 95% CI 0.70-1.00, p = 0.015) and pulmonary artery (PA) pressure (AUC 0.82, 95% CI 0.65-0.98, p = 0.029) were predictive for the combined endpoint. The predictive value of the MELD-XI for the combined endpoint was further improved when integrating PA pressure, RA pressure, and RV pressure in the model (AUC 0.91, 95% CI 0.77-1.00, p = 0.002).</p><p><strong>Conclusion: </strong>This pilot study identified MELD-XI score as a potential risk score for 3‑month mortality after TTVI. Its prognostic value for the combined endpoint was increased after adding invasive hemodynamic parameters.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"495-507"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145966840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal imaging manifestations of rare pancreatic ductal adenocarcinoma with metastasis to soleus muscle.","authors":"Juan Liu, Zhen Liu, Zhen-Hua Liu, Pei Hu","doi":"10.1007/s00508-026-02707-x","DOIUrl":"10.1007/s00508-026-02707-x","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"508-510"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146107530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"War orphan age at father loss and resilience in late adolescence.","authors":"Nermina Kravić, Izet Pajević, Mevludin Hasanović, Santiago de Leon-Martinez, Thomas Niederkrotenthaler, Martin Voracek, Kanita Dervic","doi":"10.1007/s00508-025-02699-0","DOIUrl":"10.1007/s00508-025-02699-0","url":null,"abstract":"<p><strong>Background: </strong>War orphans have been reported to have unfavorable psychological outcomes; however, research on the impact of an orphan's age at father loss on later mental health and resilience is scarce.</p><p><strong>Methods: </strong>In a sample of 50 orphans (mean age 18.9 SD ± 1.5 years, age range 16-21 years, 54%, N = 27 female) who lost their father before the age of 5 years during the war in Bosnia and Herzegovina (1992-1995), the relationships between age at father loss, sociodemographic/environmental factors, and mental health characteristics including resilience in late adolescence were assessed using Pearson correlations, t‑tests, ANOVA and regression analyses.</p><p><strong>Results: </strong>After controlling for confounders, regression analyses revealed that younger age at father loss was independently associated with lower total resilience (p = 0.001) in late adolescence and lower acceptance of self and life (p = 0.006). Education mediated the relationship between age at father loss and later self-reported depression, with higher educational levels being associated with less depressive symptoms. Furthermore, being the only child was associated with higher total resilience (p = 0.015), personal competence (p = 0.020) and acceptance of self and life (p = 0.041).</p><p><strong>Conclusion: </strong>Our findings suggest that very early loss of a father creates a specific vulnerability, impacting war orphans' resilience in late adolescence. Resilience-focused interventions should focus on war orphans who lost their fathers at a very young age and those having siblings.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"462-469"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the relationship between mothers' carbohydrate counting knowledge and glycemic control in children with type 1 diabetes.","authors":"Sercan Özbek Yazici, Beyza İlişiksiz, Sümeyye Kemaneci, Mustafa Özgür Pirgon","doi":"10.1007/s00508-025-02696-3","DOIUrl":"10.1007/s00508-025-02696-3","url":null,"abstract":"<p><strong>Background: </strong>Carbohydrate counting (CC) supports glycemic control. In children with type 1 diabetes mellitus (T1DM), mothers are usually the primary caregivers and parental knowledge and involvement play a key role in diabetes management.</p><p><strong>Objective: </strong>This study aims to evaluate mothers' knowledge of CC and the impact of their knowledge level on glycemic control (glycated hemoglobin, HbA1c) in children and adolescents with T1DM.</p><p><strong>Methods: </strong>The research was an analytical cross-sectional study conducted at the Pediatric Endocrinology Polyclinic. This study was conducted with 102 mothers of children and adolescents with T1DM. Mothers' CC knowledge was assessed using a test designed by the researchers. All participants completed demographic and clinical questionnaires. The measurement of HbA1c was used to evaluate glycemic control, where HbA1c levels < 7.5% represented good control and ≥ 7.5% indicated poor control. Multiple linear regression analysis was performed to evaluate the determinants of HbA1c (%).</p><p><strong>Results: </strong>The mean HbA1c level of children and adolescents was 8.3% ± 1.87, with only 35.3% achieving good glycemic control. The study demonstrated that mothers possess a certain level of CC knowledge. Children and adolescents of mothers who had received a university education had lower HbA1c levels (p < 0.05). There was no significant relationship between mothers' education levels and their CC knowledge score. The HbA1c levels showed a negative correlation with mothers' CC knowledge score (r:-0.315). Mothers of children with good glycemic control had a significantly higher CC knowledge score (p < 0.05). The CC knowledge score of mothers had a negative correlation with HbA1c (%). In multiple regression analyses mothers' education levels (B:-0.318, p < 0.05) and CC knowledge score (B:-0.177, p < 0.05) were significant predictors of HbA1c, explaining 20.8% of the variance.</p><p><strong>Conclusion: </strong>The findings suggest that there is a need to enhance mothers' CC knowledge. Mothers' CC knowledge levels were found to affect their children's glycemic control. Therefore, regular training should be provided to improve healthy eating habits and accurate carbohydrate counting knowledge, and mothers' knowledge levels should be assessed to address any gaps.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"470-477"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13493431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MUW researcher of the month: Dr.in Mariem Radhouani.","authors":"","doi":"10.1007/s00508-026-02795-9","DOIUrl":"https://doi.org/10.1007/s00508-026-02795-9","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"138 15-16","pages":"513-514"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic hepatitis D in Austria: high burden of cirrhosis and portal hypertension, IL28B C/C as unfavorable factor, increased systemic inflammation in decompensation.","authors":"Michael Schwarz, Caroline Schwarz, David J M Bauer, Marlene Panzer, Marlene Hintersteininger, Michael Strasser, Silvia Reiter, Livia Dorn, Michael Trauner, Albert Friedrich Stättermayer, Mattias Mandorfer, Andreas Maieron, Alexander Moschen, Elmar Aigner, Heinz Zoller, Michael Gschwantler, Thomas Reiberger, Mathias Jachs","doi":"10.1007/s00508-026-02700-4","DOIUrl":"10.1007/s00508-026-02700-4","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic hepatitis D (CHD) is a severe viral hepatitis characterized by a rapid progression towards advanced chronic liver disease (ACLD). This study aimed to characterize the Austrian CHD epidemiology with respect to disease severity, systemic inflammation and genetic markers.</p><p><strong>Methods: </strong>Patients attending one of six participating hospitals from 2020 onwards were included and assessed regarding laboratory data, liver stiffness measurement (LSM) and biopsy, hepatic venous pressure gradient (HVPG) measurement, endoscopy and imaging. In a subset, single nucleotide polymorphisms (SNPs) in genes of interest (IL28B, PNPLA3, SERPINA1, NTCP) were assessed. Biomarkers of liver disease severity were compared to an age-matched cohort of treatment-eligible and treatment-naïve chronic hepatitis B (CHB) patients.</p><p><strong>Results: </strong>A total of 59 CHD patients (median age: 44.0 years, 59.3% male) were included and ACLD was found in 62.7%. Decompensated patients exhibited higher levels of biomarkers of systemic inflammation, such as C‑reactive protein (p = 0.061) and interleukin 6 (p = 0.008). The SNP IL28B C/C genotype had an unfavorable effect on disease severity (higher Model for End-Stage Liver Disease [MELD] score, HVPG and ammonia levels, lower platelet counts and albumin levels, all p < 0.05). The CHD patients showed a more severe liver disease compared to CHB mono-infected patients with respect to LSM, platelets, MELD and portal hypertension (all p < 0.01).</p><p><strong>Conclusion: </strong>This analysis of the Austrian CHD cohort before initiation of antiviral treatment showed a high burden of ACLD and portal hypertension, especially when compared to CHB patients. The IL28B C/C SNP was associated with a more severe liver disease in CHD.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"483-494"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13493468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146126527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}