Wiener Klinische Wochenschrift最新文献

{"title":"ÖGP Grants & Stipendien 2025.","authors":"","doi":"10.1007/s00508-025-02534-6","DOIUrl":"https://doi.org/10.1007/s00508-025-02534-6","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 7-8","pages":"259"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MUW researcher of the month.","authors":"","doi":"10.1007/s00508-025-02536-4","DOIUrl":"https://doi.org/10.1007/s00508-025-02536-4","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 7-8","pages":"257-258"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts.","authors":"","doi":"10.1007/s00508-025-02510-0","DOIUrl":"https://doi.org/10.1007/s00508-025-02510-0","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 Suppl 2","pages":"35-141"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"mitteilungen der gesellschaft der ärzte in wien.","authors":"","doi":"10.1007/s00508-025-02537-3","DOIUrl":"https://doi.org/10.1007/s00508-025-02537-3","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 7-8","pages":"260"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of a rectal neuroendocrine neoplasm growing within a lipoma with ulcerative lesions.","authors":"Xiaodan Zhang, Houyu Duan, Simei Yue, Lingjiao Gong, Fei Liao","doi":"10.1007/s00508-024-02498-z","DOIUrl":"10.1007/s00508-024-02498-z","url":null,"abstract":"<p><p>Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with different immunophenotypes, morphological features, clinical presentations, and outcomes. Therefore, the diversity of NENs can easily confuse clinicians and lead to misdiagnosis. This article reports a case of a rectal NEN (r-NEN) growing within a lipoma with ulcerative lesions, which had been mistaken for rectal cancer. Fortunately, an experienced surgeon questioned the initial diagnosis (rectal cancer) after combining the results of a colonoscopic biopsy and the digital anorectal examination, thus enabling the patient to avoid unnecessary surgery. Through the review of this case and relevant literature, we further analyze the growth pattern of NENs and lipomas. Additionally, we hope to enhance clinicians' awareness of a NEN that grew insidiously within a lipoma with surface ulcerative lesions, to make accurate diagnoses and treatments in time.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":"248-250"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of pentoxifylline for major depressive disorder : A systematic review and meta-analysis of randomized controlled trials.","authors":"Chia Siang Kow, Dinesh Sangarran Ramachandram, Syed Shahzad Hasan, Zhiyun Wong, Kaeshaelya Thiruchelvam","doi":"10.1007/s00508-025-02519-5","DOIUrl":"https://doi.org/10.1007/s00508-025-02519-5","url":null,"abstract":"<p><strong>Background: </strong>Major depressive disorder (MDD) is a widespread mental health issue; however, despite various antidepressant treatments many patients do not achieve full remission or continue to experience residual symptoms. This systematic review and meta-analysis evaluated the efficacy of pentoxifylline for MDD.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted to identify randomized controlled trials (RCT) that evaluated the efficacy of pentoxifylline as an adjunctive therapy in the treatment of MDD. This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data were pooled using a random effects meta-analysis model due to the expected heterogeneity among studies.</p><p><strong>Results: </strong>Four studies met the inclusion criteria and were included. The included studies comprised a total of 292 participants diagnosed with MDD. Participants' ages ranged from 18 to 65 years, and all had a Hamilton Depression Rating Scale (HAM-D) score of at least 18. The pooled analysis showed a significant improvement in response rates for the pentoxifylline group compared to the control group (pooled odds ratio [OR] 6.85, 95% confidence interval, CI: 3.42, 13.73), indicating a much higher likelihood of treatment response. Remission rates favored the pentoxifylline group, with a pooled OR of 6.09 (95% CI: 3.11, 11.91), suggesting a significantly higher likelihood of achieving remission with pentoxifylline.</p><p><strong>Conclusion: </strong>Our findings support the potential of pentoxifylline as an effective treatment for MDD; however, further research is needed to fully establish its efficacy across different patient populations.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lupus and IgA nephropathy: coexistence or coincident?","authors":"Rahime Duran, Derya Yıldırım, Rıza Can Kardaş, İbrahim Vasi, Burcugül Kaya, Yahya Çakır, İbrahim Karaduman, Hamit Küçük, Berna Göker, Mehmet Akif Öztürk, Abdulsamet Erden","doi":"10.1007/s00508-025-02512-y","DOIUrl":"https://doi.org/10.1007/s00508-025-02512-y","url":null,"abstract":"<p><strong>Background: </strong>Systemic lupus erythematosus is a multisystem autoimmune disease primarily manifesting as lupus nephritis. While lupus nephritis is the most common renal pathology in lupus, non-lupus nephropathies such as IgA nephropathy occasionally occur. This study aims to evaluate the clinical features and outcomes of lupus patients with IgA nephropathy, comparing them with those of primary IgA nephropathy and lupus nephritis.</p><p><strong>Methods: </strong>A comprehensive literature review was conducted using the PubMed and Google Scholar databases to identify cases of systemic lupus erythematosus with IgA nephropathy reported between 1995 and December 2023. A total of 16 cases were identified and 2 additional cases from our clinic were included. These cases were compared with 47 lupus nephritis patients from our clinic and 215 primary IgA nephropathy patients from the literature. Data were collected on demographics, serology, renal biopsy findings, treatment, progression to renal failure and mortality.</p><p><strong>Results: </strong>We identified 18 cases of lupus with IgA nephropathy with a median age of 41.6 years and a female predominance (72.2%). In comparison to the primary IgA nephropathy cohort, lupus with IgA nephropathy group exhibited a lower rate of renal failure (11.1% vs. 34%) and mortality (5.6% vs. 20%). Additionally, the lupus-IgA nephropathy group showed a slightly lower mortality rate compared to the lupus nephritis cohort (5.6% vs. 10.6%).</p><p><strong>Conclusion: </strong>Lupus with predominantly IgA deposits often follows a more indolent course than primary IgA nephropathy but severe cases with crescentic glomerulonephritis can still progress to renal failure.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility, acceptance and effects of pulsed magnetic field therapy in patients with post-COVID-19 fatigue syndrome : A randomized controlled pilot study.","authors":"Mohammad Keilani, Margarete Steiner, Julia Sternik, Jim Schmeckenbecher, Ralf Harun Zwick, Barbara Wagner, Richard Crevenna","doi":"10.1007/s00508-025-02522-w","DOIUrl":"https://doi.org/10.1007/s00508-025-02522-w","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this randomized, single-blinded, placebo-controlled pilot study was to explore the feasibility, acceptance and effects of pulsed electromagnetic field therapy (PEMF) in patients with post-COVID-19 fatigue syndrome.</p><p><strong>Methods: </strong>A total of 20 patients were included in the study. They were randomly assigned to an intervention group (n = 10, male:female = 4 : 5, age = 45 ± 9 years) and a placebo group (n = 10, m:f = 4:6, age: 39 ± 23 years). A Papimi™ Delta professional electromagnetic field therapy device was used for treatment. Controls received a placebo PEMF. In total 10 PEMF sessions (30 min., 2× per week) were applied. Physical performance, health-related quality of life, fatigue, work ability, sleep, pain, anxiety and depression were assessed at baseline, posttreatment and at follow-up 5 weeks after treatment. Feasibility and acceptance were assessed posttreatment.</p><p><strong>Results: </strong>The intervention group showed a notable improvement in the 6 minutes walking test. The use of PEMF improved fatigue (measured with the Brief Fatigue Inventory and the Multidimensional Fatigue Inventory). Also, the depression subscale of the Hospital Anxiety and Depression Scale, the Insomnia Severity Index, the Work Ability Index and most subscales of the Short Form (SF) 36 questionnaire showed improvement. From the placebo group three patients dropped out. There were no drop-outs in the intervention group. In the intervention group, PEMF was well-accepted and patients showed very good adherence.</p><p><strong>Conclusion: </strong>The results of this pilot study indicate that PEMF is feasible and well accepted. Furthermore, this study population showed improvements in physical and mental health in the intervention group. This study is a promising contribution to this growing research field and provides the required evidence for future efficacy studies on PEMF for post-COVID-19 patients.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifocal white plaques on the tongue: isolated oral manifestation of secondary syphilis.","authors":"Yuri de Lima Medeiros, Maria Emília Mota, Daniel Amaral Alves Marlière","doi":"10.1007/s00508-025-02515-9","DOIUrl":"https://doi.org/10.1007/s00508-025-02515-9","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrence of sexually transmitted infections is commonly found in a subpopulation of Austrian users of HIV pre-exposure prophylaxis.","authors":"Nikolaus Urban, Thomas Neidhart, Katharina Grabmeier-Pfistershammer, Veronique Touzeau-Roemer, Kaspar Laurenz Schmidt, Robert Strassl, Wolfgang Weninger, Birgit Willinger, Wolfgang Michael Bauer, David Chromy","doi":"10.1007/s00508-025-02499-6","DOIUrl":"https://doi.org/10.1007/s00508-025-02499-6","url":null,"abstract":"<p><strong>Background: </strong>In recent years there has been an increase in the diagnoses of sexually transmitted infections (STI) among men who have sex with men (MSM) using human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP); however, data on PrEP users in Austria are limited.</p><p><strong>Patients, material and methods: </strong>In June 2020, we initiated a prospective observational cohort study at Vienna General Hospital including PrEP users from Vienna. Participants underwent STI testing quarterly and provided behavioral information using a questionnaire.</p><p><strong>Results: </strong>Between June 2020 and December 2023 a total of 360 individuals (99% MSM) were enrolled comprising 379 person-years of follow-up. We identified 276 STIs in 154 individuals, of which 23% (36/154) were symptomatic. The incidence rates per 100 person-years were 29.9 (95% confidence interval, CI 24.3-35.3 per 100 person-years) for gonorrhea, 22.7 (95% CI 17.9-27.5 per 100 person-years) for chlamydia and 9.8 (95% CI 6.6-12.9 per 100 person-years) for syphilis. Extragenital infections accounted for 95% (97/102) of gonorrhea and 81% (65/80) of chlamydia cases. A case of HIV infection was recorded in a 20-year-old male with inconsistent PrEP use. Participants with one or more reinfection (18%; 65/360) accounted for 68% (187/276) of all STIs. Sexualized drug use (Chemsex) was reported by 44% (157/360) of participants and was significantly associated with higher rates of gonorrhea (38% vs. 21%, p < 0.001) and syphilis (17% vs. 5%, p < 0.001) but not chlamydia (26% vs. 19%, p = 0.118).</p><p><strong>Conclusion: </strong>Throughout the study, 43% of participants experienced a bacterial STI, which was mostly asymptomatic and at extragenital sites. Chemsex was commonly reported and identified as a predictor for STI reinfection, underlining the importance of harm reduction strategies in Austrian STI prevention.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}