{"title":"Regarding Gampenrieder et al., A comparison of breast cancer incidence and cancer stages before and after the introduction of the Austrian national breast cancer screening program in the federal state of Salzburg.","authors":"Pascal A T Baltzer, Paola Clauser","doi":"10.1007/s00508-025-02555-1","DOIUrl":"https://doi.org/10.1007/s00508-025-02555-1","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Fake smoke, real fire: a retrospective single-center analysis of the underestimated risk of e-cigarette explosions and the typical burn patterns\".","authors":"Renu Sah, Ankita Mathur","doi":"10.1007/s00508-025-02562-2","DOIUrl":"https://doi.org/10.1007/s00508-025-02562-2","url":null,"abstract":"","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabine Fritzenwallner, Maria Flamm, Hans-Peter Wiesinger, Dagmar Schaffler-Schaden
{"title":"Exploratory study on the self-perceived knowledge and care competence of general practitioners in managing patients with overweight and obesity in Austria.","authors":"Sabine Fritzenwallner, Maria Flamm, Hans-Peter Wiesinger, Dagmar Schaffler-Schaden","doi":"10.1007/s00508-025-02545-3","DOIUrl":"https://doi.org/10.1007/s00508-025-02545-3","url":null,"abstract":"<p><strong>Objectives: </strong>Obesity is a chronic, multifactorial disease that is often described as an epidemic or pandemic of the 21st century. General practitioners (GPs) play a crucial role in managing it, yet multiple barriers hinder effective care. This study explores Austrian GPs' experiences in obesity management, their self-assessed knowledge and care competencies, and the perceived barriers to optimal treatment.</p><p><strong>Methods: </strong>A quantitative online survey was conducted among GPs in October and November 2023. The questionnaire covered prevention, treatment, barriers, and experiences in managing overweight and obesity in primary care.</p><p><strong>Results: </strong>In all, 59 GPs (56% female) completed the survey. Nearly all recognized obesity as a chronic disease and felt responsible for its management, but almost half considered their training insufficient. While 80% acknowledged the need for multimodal therapy programs, awareness of available healthcare services was low. The most significant barrier to effective obesity care from the GP's point of view was a lack of patient motivation. Female GPs were more likely to screen for dietary habits and physical activity, refer patients to specialized care, and request additional resources, whereas male GPs were more likely to prescribe pharmacotherapy. More experienced GPs felt better trained but were less likely to seek treatment guidelines. Regional and practice-setting differences influenced attitudes and referral patterns. GPs with private insurance contracts felt best trained and were least likely to request additional support.</p><p><strong>Conclusion: </strong>The survey revealed considerable uncertainty among GPs regarding the management of overweight and obesity. These findings highlight the need for targeted interventions to improve patient care and enhance GPs' training in obesity management.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siroos Mirzaei, Gregor Schweighofer-Zwink, Heidemarie Ofner, Jasmin Bektic, Harun Fajkovic, Eisabeth von Guggenberg, Anton Ponholzer, Gero Kramer, Lukas Lusuardi, Michael Gabriel, Tatjana Traub-Weidinger, Marcus Hacker, Shahrokh F Shariat
{"title":"Use of <sup>177</sup>Lu prostate-specific membrane antigen therapy in metastatic castration-resistant prostate cancer : Joint statement of the Austrian Society of Nuclear Medicine and Theranostics and the Austrian Society of Urology and Andrology.","authors":"Siroos Mirzaei, Gregor Schweighofer-Zwink, Heidemarie Ofner, Jasmin Bektic, Harun Fajkovic, Eisabeth von Guggenberg, Anton Ponholzer, Gero Kramer, Lukas Lusuardi, Michael Gabriel, Tatjana Traub-Weidinger, Marcus Hacker, Shahrokh F Shariat","doi":"10.1007/s00508-025-02544-4","DOIUrl":"10.1007/s00508-025-02544-4","url":null,"abstract":"<p><p>Prostate cancer (PCa) remains a leading cause of cancer-related morbidity and mortality in men. Over the past decades, the incidence has risen in all age groups. Prostate-specific membrane antigen (PSMA)-based theranostics, which involve the use of PSMA-targeting radiopharmaceuticals for both diagnostic imaging and therapeutic applications, have become integral in the management of patients with metastatic castration-resistant prostate cancer (mCRPC). The field has witnessed a substantial and continuously expanding body of scientific literature, encompassing case reports, original research, systematic reviews and also clinical guidelines. The objective of this joint statement is to enhance awareness of PSMA theranostics and underscore their critical role in contemporary precision oncology. We aim to provide a comprehensive yet practical perspective on the current landscape of PSMA-based diagnostic and therapeutic modalities, offering a consensus-driven approach to their clinical application.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":"137 Suppl 4","pages":"157-166"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Tscherny, Juergen Grafeneder, Bettina Wandl, Maximilian Niederer, Martina Haider, Eva Katharina Masel, Dominik Roth, Alexander Egger
{"title":"Symptom tracking made simple? Observational data on the clinical use of the PERS<sup>2</sup>ON score in cancer patients receiving palliative care.","authors":"Katharina Tscherny, Juergen Grafeneder, Bettina Wandl, Maximilian Niederer, Martina Haider, Eva Katharina Masel, Dominik Roth, Alexander Egger","doi":"10.1007/s00508-025-02553-3","DOIUrl":"https://doi.org/10.1007/s00508-025-02553-3","url":null,"abstract":"<p><strong>Context: </strong>A standardized assessment of symptoms is essential for individualized palliative care (PC). While numerous tools exist, many are too complex for daily clinical use.</p><p><strong>Objective: </strong>The PERS<sup>2</sup>ON score was developed as a brief and practical tool to assess symptom burden in PC. This study aimed to evaluate its feasibility in a rural hospital setting, although it did not include formal feasibility metrics such as recruitment or adherence rates.</p><p><strong>Methods: </strong>Patients admitted to the palliative care unit of a rural hospital were assessed using the PERS<sup>2</sup>ON score, which includes seven items: pain, eating, rehabilitation, social situation, suffering, oxygen/dyspnea, and nausea/emesis. Each item is scored from 0 to 10, with higher scores indicating greater burden. Assessments were conducted on admission, after 7 days, and at discharge. Symptom scores were analyzed for change over time.</p><p><strong>Results: </strong>Of 60 admitted patients, 40 met the inclusion criteria. Reassessment was possible in 35 patients after 7 days and in 31 patients at discharge. The mean PERS<sup>2</sup>ON score decreased from 28 (SD 12) on admission to 21 (SD 11) after 7 days (difference: 7, 95% confidence interval, CI: 3-11, p = 0.002), and to 17 (SD 10) at discharge (difference: 11, 95% CI: 6-15, p < 0.001).</p><p><strong>Conclusion: </strong>The PERS<sup>2</sup>ON score was feasible to implement and enabled consistent symptom monitoring. Its use may support structured clinical assessment and targeted symptom management even in smaller or rural palliative care units.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix Hofbauer, Laura Strobel, Christian Marth, Andreas Widschwendter
{"title":"Behavioral recommendations following gynecological surgery.","authors":"Felix Hofbauer, Laura Strobel, Christian Marth, Andreas Widschwendter","doi":"10.1007/s00508-025-02548-0","DOIUrl":"https://doi.org/10.1007/s00508-025-02548-0","url":null,"abstract":"<p><strong>Background: </strong>Postoperative care is critical for recovery after gynecological procedures. Yet, the absence of consistent guidelines often leaves patients uncertain, potentially hindering healing. This study aimed to assess behavioral recommendations provided by Austrian gynecologists and hospitals to inform the development of standardised postoperative guidance.</p><p><strong>Patients and methodology: </strong>Between December 2023 and April 2024, questionnaires were sent to 118 gynecologists and 79 hospitals, covering postoperative advice for hysteroscopy, large loop excision of the transformation zone (LLETZ) conisation, tension-free vaginal tape (TVT), laparoscopy, hysterectomy, and caesarean section. Topics included duration of sick leave, follow-up, bathing, tampon use, sexual activity, sports, and lifting restrictions.</p><p><strong>Results: </strong>Responses were received from 54 gynecologists (46%) and 49 clinics (62%). Clinics tended to recommend more restrictive measures than specialists, particularly for LLETZ, TVT, and laparoscopy, while advice aligned for hysterectomy and caesarean section. Notably, for LLETZ conisation, specialists advised 2-4 weeks of rest, whereas clinics recommended 1-2 weeks (p < 0.05). For hysterectomy and caesarean section, both groups advised 4-6 weeks of recovery, with restrictions on weight lifting, sexual activity, and sports. Variability was also seen in the basis for recommendations: 41% of specialists relied on personal experience, while 41% of clinics cited current evidence.</p><p><strong>Conclusion: </strong>This study highlights significant heterogeneity in postoperative advice across Austria and underscores the need for evidence-based, standardised guidelines to improve the quality and consistency of care in gynecology.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patrick Haselwanter, Seanna Fairfield, Marlene Riedl-Wewalka, Monika Schmid, Albert Friedrich Stättermayer, Thomas Reiberger, Michael Trauner, Christian Zauner, Mathias Schneeweiss-Gleixner
{"title":"Acute liver failure in patients admitted to the intensive care unit-a Viennese retrospective single-center analysis.","authors":"Patrick Haselwanter, Seanna Fairfield, Marlene Riedl-Wewalka, Monika Schmid, Albert Friedrich Stättermayer, Thomas Reiberger, Michael Trauner, Christian Zauner, Mathias Schneeweiss-Gleixner","doi":"10.1007/s00508-025-02539-1","DOIUrl":"https://doi.org/10.1007/s00508-025-02539-1","url":null,"abstract":"<p><strong>Background: </strong>Acute liver failure (ALF) is characterized by a rapid deterioration of liver function and a high mortality without transplantation depending on etiology and onset. Immediate transfer to a dedicated intensive care unit (ICU) and evaluation for high-urgency liver transplantation (HU-LTx) is recommended to maximize chances of survival. Data on ALF epidemiology are limited, particularly for Central Europe.</p><p><strong>Methods: </strong>This retrospective single-center study included all ALF patients admitted to the ICU of the Department of Gastroenterology and Hepatology at the Vienna General Hospital between 2012 and 2024.</p><p><strong>Results: </strong>Overall, 31 patients (median age of 44 [interquartile range, IQR 32-56] years, 20 [65%] female) were included. The primary causes of ALF were viral infections (n = 8; 26%), autoimmune hepatitis (n = 5; 16%), drug-induced liver injury (DILI; n = 3; 10%), and Wilson's disease (n = 4; 13%), while in 8 patients (26%) no cause was identified. Median length of ICU stay was 12 (IQR 4-21) days, with mean sequential organ failure assessment (SOFA) and simplified acute physiology score II (SAPS II) scores of 10.55 ± 4.56 and 40.97 ± 14.84. Overall ICU survival was 61% (n = 19). Non-HU-LTx patients (n = 18) had an ICU survival of 44%. HU-LTx was performed in 13 patients (42%), with 12 patients (92%) surviving 28 days. The 6‑month overall survival of HU-LTx patients was 85%.</p><p><strong>Conclusion: </strong>The diverse causes of ALF in Central Europe include most commonly viral infections, autoimmune hepatitis, and DILI. HU-LTx was required and performed in almost half of patients and was associated with favorable survival rates, underscoring the importance of ICU management and early transfer to liver transplantation centers in the management of ALF.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elias Marquart, Doris Weiss, Klaudija Batinic, Thomas Wiesner, Johannes Rohrbeck, Tamara Arnoldner, Wolfgang Weninger, Tamar Kinaciyan
{"title":"Completely ulcerated infantile hemangioma: a diagnostic challenge.","authors":"Elias Marquart, Doris Weiss, Klaudija Batinic, Thomas Wiesner, Johannes Rohrbeck, Tamara Arnoldner, Wolfgang Weninger, Tamar Kinaciyan","doi":"10.1007/s00508-025-02543-5","DOIUrl":"https://doi.org/10.1007/s00508-025-02543-5","url":null,"abstract":"<p><p>The present case report describes a completely ulcerated infantile hemangioma (UIH) in a 5-month-old infant on the left proximolateral thigh initially misdiagnosed as pyoderma gangrenosum, sporotrichosis or atypical mycobacterial infection. Clinical assessment, histological findings, and GLUT‑1 immunohistochemistry confirmed the diagnosis of UIH. Systemic propranolol treatment led to rapid ulcer healing within 3 weeks and complete recovery without relapse after 18 months of treatment. The report emphasizes the diagnostic challenges, effective propranolol treatment and the importance of considering UIH in the differential diagnoses of solitary pediatric ulcers.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lukas Neumann, Rafael Brader, Lili Kazemi-Shirazi, Michael Trauner, Christian Primas, Karin Wisniowski, Jurij Maurer, Hansjörg Schlager, Jagoda Pokryszka, Clemens Dejaco, Walter Reinisch, Gottfried Novacek, Philipp Schreiner
{"title":"No increase of biopsy rates despite high rates of probable eosinophilic esophagitis in patients with esophageal food impaction.","authors":"Lukas Neumann, Rafael Brader, Lili Kazemi-Shirazi, Michael Trauner, Christian Primas, Karin Wisniowski, Jurij Maurer, Hansjörg Schlager, Jagoda Pokryszka, Clemens Dejaco, Walter Reinisch, Gottfried Novacek, Philipp Schreiner","doi":"10.1007/s00508-025-02542-6","DOIUrl":"https://doi.org/10.1007/s00508-025-02542-6","url":null,"abstract":"<p><strong>Introduction: </strong>Eosinophilic esophagitis (EoE) is one of the main causes of esophageal food impaction (EFI). Since only few endoscopists take biopsies during the emergency endoscopy at EFI presentation, as is recommended by current guidelines, a high number of patients will not have a proper diagnosis after EFI. Hence, we investigated the change of biopsy rates and the etiology of EFI over 11 years.</p><p><strong>Methods: </strong>All patients presenting at the emergency department (ED) of a tertiary center with an EFI who underwent esophagogastroduodenoscopy (EGD) between 2013 and 2023 were included. Clinical and endoscopic variables were analyzed retrospectively. We performed a binary logistic regression model to predict biopsy performance.</p><p><strong>Results: </strong>A total of 180 EFI cases (67% male, median age 57 years) were recorded between 2013 and 2023. Overall, esophageal biopsies were taken only in 18% without any increase over time. In patients ≥ 50 years of age (n = 108), the etiology remained unknown in half of patients (48%), followed by gastroesophageal reflux disease (GERD; 23%) and EoE (18%). However, in patients < 50 years of age, EoE was the main suspected etiology in 69% of cases. Biopsies were obtained in only 18% of all patients with suspected EoE. Age, gender, and the year of EFI were not associated with biopsy performance. However, the probability of biopsy increased by a factor of 4.03 in the presence of suspected EoE by the endoscopist.</p><p><strong>Conclusion: </strong>Despite an increasing awareness of EoE, the biopsy rate in EFI is rather low. Routine biopsies should be taken to shorten diagnostic delay.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harald Herkner, Alexandra J Lipa, Philip Eisenburger, Wilhelm Behringer, Alexander Spiel, Sonja Mahrer, Moritz Haugk, Rainer Thell, Marie-Kathrin Breyer, Nicole Biber, Edith Doberer, Anna Kreil, Michael Schwameis
{"title":"Structural quality criteria of emergency departments in Vienna.","authors":"Harald Herkner, Alexandra J Lipa, Philip Eisenburger, Wilhelm Behringer, Alexander Spiel, Sonja Mahrer, Moritz Haugk, Rainer Thell, Marie-Kathrin Breyer, Nicole Biber, Edith Doberer, Anna Kreil, Michael Schwameis","doi":"10.1007/s00508-025-02541-7","DOIUrl":"https://doi.org/10.1007/s00508-025-02541-7","url":null,"abstract":"<p><strong>Background: </strong>In 2020, the Austrian Association of Emergency Medicine proposed structural quality criteria for in-hospital emergency care in Austria. However, it has not yet been assessed how these criteria apply to existing emergency departments.</p><p><strong>Methods: </strong>All in-hospital emergency departments across Vienna were surveyed using a structured assessment based on published proposed structural quality criteria. A total of 54 criteria were analysed, each rated on a scale of 3 (comprehensive care), 2 (standard care), 1 (basic care), or 0 (not met).</p><p><strong>Results: </strong>Among 16 hospitals, we identified 10 emergency departments. The scores ranged from 87 points (54%) to 151 points (95%). None of the departments met all structural quality criteria. Overall, across all emergency departments, 69% of the criteria aligned with comprehensive care, 7% with standard care and 3% with basic care, while 21% of the criteria were not met at all.</p><p><strong>Conclusions: </strong>A set of proposed structural quality criteria for emergency departments could be quantitatively assessed. While the published criteria and the observed infrastructure are largely consistent, there is significant potential for improvement in both the definition of the criteria and the criteria per se. The extent to which these structural quality criteria are useful for assessing the classification of tiered care models requires further studies in different regions.</p>","PeriodicalId":23861,"journal":{"name":"Wiener Klinische Wochenschrift","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}