World Journal of Surgical Oncology最新文献

{"title":"Not all prolific letter writers are alike.","authors":"Shigeki Matsubara","doi":"10.1186/s12957-026-04584-0","DOIUrl":"10.1186/s12957-026-04584-0","url":null,"abstract":"<p><p>Concerns have recently been raised that AI-assisted \"letter-bombing\" may distort medical publishing. Although I share these concerns, prolific Letter writing can arise for legitimate reasons. Using my own publication history as an example, I illustrate how retirement, loss of access to primary data, and broader academic interests naturally shifted my publications from original articles toward Letters. The problem lies not in writing many Letters, but in inappropriate motivations and misuse of AI.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Institutional modified post esophagectomy care protocol offers improved perioperative outcomes - a single-center propensity score matched analysis.","authors":"H C Hillebrecht, A Bührle, J Wang, J Hoeppner, M K Diener, S Fichtner-Feigl, J Hipp, J Kuvendjiska","doi":"10.1186/s12957-026-04588-w","DOIUrl":"https://doi.org/10.1186/s12957-026-04588-w","url":null,"abstract":"<p><strong>Background: </strong>Two-field esophagectomy for esophageal cancer and tumors of the esophagogastric junction is associated with substantial postoperative morbidity and mortality. Enhanced Recovery After Surgery (ERAS^®) protocols aim to improve perioperative outcomes through standardized multimodal care pathways. At our institution, a modified perioperative regimen has been implemented that deviates from current ERAS^® recommendations, incorporating selective oral decontamination, an enforced near-zero fluid balance, colloid administration using hydroxyethyl starch (HES), and routine nasogastric decompression.</p><p><strong>Methods: </strong>We performed a retrospective analysis of 325 consecutive patients who underwent two-field esophagectomy. Of these, 279 were treated under the modified perioperative regimen, while 46 received standard care. To adjust for baseline differences, we conducted 1:1 propensity-score matching. Postoperative outcomes, including complication rates, anastomotic leakage, Comprehensive Complication Index (CCI) and textbook outcome rates were compared between groups. This trial was prospectively registered (DRKS00024369) and approved by the Medical Ethics Committee of the University of Freiburg (Reg.-Nr. 21-1093 and 21-1713).</p><p><strong>Results: </strong>Prior to PSM, modified care group demonstrated a higher frequency of textbook outcomes and a significantly lower incidence of anastomotic leakage compared with standard care. Overall rates of major complications did not differ significantly between groups, though a trend toward reduced complication severity as measured by CCI was observed. After PSM, baseline characteristics were balanced. Rates of textbook outcome (Clavien-Dindo 0: 15.2% vs 28.3%, p=0.14) and severe complications (Clavien-Dindo ≥III: 39.1% vs 58.7%, p=0.095) were reduced but did not reach statistical significance. The CCI remained numerically lower in modified care (32.01 vs 35.70, p=0.061). Odds ratios for major complications (OR 0.45, 95% CI 0.20-1.04), anastomotic leakage (OR 0.30, 95% CI 0.06-1.59) and IMC readmission (OR 0.33, 95% CI 0.08-1.34) favored modified care but were not statistically significant. Fluid balance on POD4 and early parenteral nutrition were similar after matching. Acute kidney injury did not occur more frequently after HES-application. Overall and disease-free survival did not differ between groups.</p><p><strong>Conclusions: </strong>The modified perioperative regimen applied in this study appears to be a safe alternative to conventional ERAS®-based pathways. While definitive superiority could not be demonstrated after propensity matching, the observed trends - particularly regarding anastomotic integrity and overall complication burden - support further prospective evaluation of this approach.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13634209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serous cystadenocarcinoma of the pancreas: a population-based study.","authors":"Theodore Dotevall, Emelie Kolmodin, Ebba Thylefors, Roland Andersson, Daniel Ansari","doi":"10.1186/s12957-026-04604-z","DOIUrl":"10.1186/s12957-026-04604-z","url":null,"abstract":"<p><strong>Background: </strong>Serous cystadenocarcinoma (SCAc) of the pancreas is an exceptionally rare malignant pancreatic neoplasm, and its clinical characteristics, treatment patterns, and prognosis remain poorly defined. The aim of this population-based study was to characterize the demographic and clinical features, treatment patterns, and survival of patients with pancreatic SCAc.</p><p><strong>Methods: </strong>Patients with microscopically confirmed SCAc were identified from the Surveillance, Epidemiology, and End Results (SEER) registry. Demographic, tumor-related, treatment, and survival data were analyzed using descriptive statistics and Kaplan-Meier survival analysis.</p><p><strong>Results: </strong>Twenty-one patients with SCAc were identified. Median age at diagnosis was 69 years, and 13 patients (62%) were female. Tumors most frequently involved the pancreatic body or tail. Disease was localized in 4 patients (19%), regional in 6 (29%), distant in 9 (43%), and unstaged in 2 (10%). Surgical resection was performed in 12 patients (57%), and 6 (29%) received chemotherapy. Estimated 5-year overall survival (OS) was 60.5% for the overall cohort. Five-year OS was 73.3% among patients who underwent resection and 44.4% among those who did not.</p><p><strong>Conclusions: </strong>Pancreatic SCAc is a rare malignancy with frequent involvement of the pancreatic body or tail. Surgical resection was the most common treatment, whereas chemotherapy was used in a minority of patients. Population-based data suggest relatively favorable long-term survival.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic versus perilesional sampling in transperineal MRI-fusion biopsy: is perilesional sampling ready for prime time? A high-volume center analysis.","authors":"Agneta Seebold, Thomas Büttner, Jörg Ellinger, Glen Kristiansen, Marit Bernhardt, Alexander Isaak, Christian Hoffmann, Julian A Luetkens, Manuel Ritter, Philipp Krausewitz","doi":"10.1186/s12957-026-04606-x","DOIUrl":"10.1186/s12957-026-04606-x","url":null,"abstract":"<p><strong>Background: </strong>Multiparametric MRI has improved prostate cancer (PCa) diagnostics. The current standard combines MRI-targeted fusion biopsy (TB) with 12-core systematic biopsy (SB); current guidelines allow replacing SB with perilesional sampling (PB) penumbra to maintain diagnostic performance while reducing biopsy burden.</p><p><strong>Methods: </strong>We retrospectively analyzed 314 biopsy-naive men with Prostate Imaging Reporting and Data System (PI-RADS) 3-5 lesions who underwent transperineal MRI-fusion biopsy (TB plus 12-core systematic biopsy) under local anesthesia. A simulated PB strategy was evaluated post hoc by selecting four of the twelve systematic cores located in the directly adjacent sectors to the MRI-visible lesion on the standardized PI-RADS sector map and compared with SB. The primary objective was to assess whether PB replicates the diagnostic performance of SB for detecting clinically significant PCa (csPCa; ISUP grade group ≥ 2). We also compared biopsy and prostatectomy ISUP-grading, NCCN (National Comprehensive Cancer Network) -classification and the Briganti nomogram-based lymph-node metstasis risk. Statistical analyses used R and SPSS, with chi-square or Fisher's exact tests for categorial and t-tests for continuous variables; two-sided p < 0.05 was considered significant.</p><p><strong>Results: </strong>PCa was detected in 79.9% (251/314) of men, including 68.8% (216/314) with csPCa. TB alone detected 94.4% of csPCa, while SB detected 73.1%. The simulated TB + PB approach achieved 98.0% overall PCa detection and 99.1% csPCa detection (p = 0.48 vs. TB + SB). Concerning the impact on NCCN risk assessment, ISUP grade distribution was comparable across TB-based strategies, whereas SB alone detected fewer cancers and showed a trend towards lower ISUP grades. In the prostatectomy subgroup, ISUP grade concordance did not differ significantly between TB + SB and TB + PB (both 62.0%; p = 1.0). Mean Briganti scores did not differ significantly between TB + SB and TB + PB, with a minimal absolute difference of 0.17%. A 75% reduction of biopsy cores would be reached by a replacement of SB with PB. There was no significant loss of detection for csPCa (ISUP grade group 2-5; 99.1%) and no association with a loss of diagnostic yield for all ISUP grade groups. 11% reduction in detected cases was confined to ISUP grade group 1 (Supplementary Table S2).</p><p><strong>Conclusions: </strong>A TB plus 4-core PB may serve as an efficient alternative to conventional 12-core SB, without a significant reduction in diagnostic accuracy or a change in pretreatment risk assessment while markedly reducing procedural burden and resource use.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13599324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evolving role of open abdominal surgery in gynecological malignancies in the era of minimally invasive and precision oncology.","authors":"Miklos Acs, Veronika Müller, Ulrich Kaiser, Clemens Tempfer, Björn Lampe","doi":"10.1186/s12957-026-04510-4","DOIUrl":"10.1186/s12957-026-04510-4","url":null,"abstract":"<p><strong>Background: </strong>Oncological surgery is undergoing profound transformation driven by advances in systemic therapy, immunotherapy, and minimally invasive techniques. This narrative review examines whether open abdominal surgery retains clinical relevance in gynecological malignancies or has been superseded by modern alternatives.</p><p><strong>Methods: </strong>A literature search was conducted in PubMed combining terms related to gynecological malignancies, abdominal surgical procedures (open, laparoscopic, robotic, cytoreduction, pelvic exenteration), and personalized systemic therapies. Original articles, reviews, and guidelines in German and English were included. Two independent reviewers screened titles, abstracts, and full texts, extracting data on study design, interventions, and clinical endpoints (R0 resection, morbidity, progression-free and overall survival).</p><p><strong>Results: </strong>For cervical cancer, open radical abdominal hysterectomy as the standard of care was internationally confirmed. In endometrial cancer, minimally invasive approaches are established for early-stage disease, while laparotomy remains the gold standard in advanced stages requiring cytoreductive surgery. For ovarian, tubal, and primary peritoneal carcinoma, open cytoreductive surgery with the goal of macroscopically complete resection remains guideline recommended. Emerging biomarkers such as circulating tumor DNA may further refine patient selection and surgical decision-making.</p><p><strong>Conclusion: </strong>Open abdominal surgery remains indispensable in gynecological oncology. Rather than being replaced, it is evolving into a specialized, biology-adapted component of multimodal treatment strategies. Surgical indications are becoming less frequent but more complex and individualized. Patient selection in experienced centers remains the decisive factor.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Albert-Lembert coloanal anastomosis with diverting ileostomy versus Turnbull-Cutait pull-through delayed coloanal anastomosis after intersphincteric resection for low rectal cancer: a single-center retrospective comparative study.","authors":"Mengzhe Li, Hong Liang, Xi Wang, Zhanpeng Yang, Longshuai Yang, Gaojie Lian, Jianhui Li, Qingwen Fan, Chao Zhang","doi":"10.1186/s12957-026-04565-3","DOIUrl":"10.1186/s12957-026-04565-3","url":null,"abstract":"<p><strong>Background: </strong>Reconstruction after intersphincteric resection (ISR) for low rectal cancer remains technically challenging. Turnbull-Cutait pull-through delayed coloanal anastomosis (DCAA) has been used as a sphincter-preserving delayed reconstructive strategy, but it requires exteriorization of the colon and a planned second-stage perineal procedure. To improve anastomotic stability after ISR, we performed modified Albert-Lembert coloanal anastomosis (MALA) with diverting ileostomy. This study aimed to compare the short-term clinical outcomes of MALA with diverting ileostomy versus DCAA after ISR for low rectal cancer.</p><p><strong>Methods: </strong>This single-center retrospective comparative study was conducted at Henan Provincial People's Hospital. Between February 2023 and October 2025, consecutive patients with low rectal cancer who underwent laparoscopic ISR followed by hand-sewn coloanal anastomosis were reviewed. Among them, 58 patients underwent Turnbull-Cutait pull-through delayed coloanal anastomosis (DCAA group), and 42 patients underwent modified Albert-Lembert one-stage coloanal anastomosis with diverting ileostomy (MALA group). Clinical outcomes were compared between the two groups. The primary outcome was overall postoperative morbidity within 30 days after the first surgery.</p><p><strong>Results: </strong>A total of 100 patients were included, with 58 in the DCAA group and 42 in the MALA group. Baseline demographic, clinical, and tumor characteristics were comparable between the two groups. The 30-day overall postoperative morbidity rates were 32.8% and 23.8% in the DCAA and MALA groups, respectively, with no statistically significant between-group difference (P = 0.378). No statistically significant differences were observed in the rates of Clavien-Dindo grade I-II complications (19.0% vs. 16.7%, P = 0.799) or grade III or higher complications (13.8% vs. 7.1%, P = 0.350). Operative time (201.8 ± 28.6 min vs. 206.5 ± 32.4 min, P = 0.463), intraoperative blood loss [60 mL (range, 30-150) vs. 60 mL (range, 30-110), P = 0.408], harvested lymph nodes [19 (range, 15-23) vs. 22 (range, 16-24), P = 0.356], R0 resection rate (100% vs. 100%, P = 1.000), and postoperative hospital stay [15 days (range, 13-21) vs. 14 days (range, 12-20), P = 0.225] did not differ significantly between the two groups.</p><p><strong>Conclusions: </strong>MALA with diverting ileostomy is a technically feasible sphincter-preserving reconstructive strategy in selected patients undergoing laparoscopic ISR for low rectal cancer, and no statistically significant difference in 30-day postoperative morbidity was observed between the MALA and DCAA groups.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13563749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early recurrence prediction after curative-intent surgery of intrahepatic cholangiocarcinoma using a novel weighted tumor burden score.","authors":"Anna Mantas, Smiths S Lueong, Sophia Mauerer, Antonia Krumm, Dieter P Hoyer, Iakovos Amygdalos, Tom F Ulmer, Jens Siveke, Florian W R Vondran, Ulf P Neumann, Jan Bednarsch","doi":"10.1186/s12957-026-04560-8","DOIUrl":"10.1186/s12957-026-04560-8","url":null,"abstract":"<p><strong>Background: </strong>Recurrence after curative-intent resection of patients with intrahepatic cholangiocarcinoma (ICC) remains common and difficult to predict. Tumor burden scores (TBS) incorporating tumor size and tumor nodule number have been proposed, but the relative contribution of multifocality remains unclear.</p><p><strong>Methods: </strong>Patients undergoing curative-intent surgery for ICC in a large hepatobiliary center between 2009 and 2024 were retrospectively analyzed. A simplified weighted tumor burden score (wTBS) was developed using tumor size and tumor nodule number (wTBS = largest tumor diameter (cm) + 5 × tumor nodule number). The score was derived in a primary cohort and externally validated in an independent cohort. Early recurrence was defined as recurrence within 12 months after surgery. Predictive performance was assessed using logistic regression analysis, receiver operating characteristic (ROC) analysis, Kaplan-Meier survival curve analysis and Cox regression models.</p><p><strong>Results: </strong>A total of 198 patients were included in this study. In the study cohort, the wTBS was significantly associated with early recurrence (OR 1.12 per point, 95% CI 1.07-1.18, p < 0.001) and recurrence-free survival (RFS; HR 1.06 per point, 95% CI 1.04-1.09, p < 0.001). ROC analysis demonstrated improved discriminatory performance compared to tumor size or tumor nodule number alone (area under the curve [AUC] 0.69). Using a cutoff of ≥ 14, patients with high wTBS had significantly shorter RFS (median 9 vs. 21 months, p < 0.001). These findings were confirmed in an independent validation cohort comprising 162 patients, in which wTBS remained significantly associated with early recurrence (OR 1.12) and RFS (HR 1.08, p < 0.001) with a median RFS of 7 vs. 26 months for high- vs. low-risk patients.</p><p><strong>Conclusions: </strong>A simplified wTBS incorporating tumor size and tumor nodule number was associated with early recurrence after ICC resection and showed consistent prognostic value in an independent cohort. Given its moderate discriminatory ability, the score should currently be regarded as an adjunct for postoperative risk stratification rather than a stand-alone tool for treatment selection. Prospective validation and evaluation of clinical utility are required before implementation in treatment algorithms.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148832233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note: TRIM58 functions as a tumor suppressor in colorectal cancer by promoting RECQL4 ubiquitination to inhibit the AKT signaling pathway.","authors":"Naizhi Sun, Jiacheng Shen, Yuhua Shi, Biao Liu, Shengguo Gao, Yichuan Chen, Jinwei Sun","doi":"10.1186/s12957-026-04545-7","DOIUrl":"10.1186/s12957-026-04545-7","url":null,"abstract":"","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148832220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erector spinae plane block (ESPB) versus paravertebral plane block (PVB) in managing post-operative pain in breast cancer patients: a systematic review and meta-analysis.","authors":"Basma M El-Khalifa, Hamza Khelifa, Mahmoud Mohamed Gad, Bahaa Elfakharany, Mohamed Sherif Ali Ahmed, Asmaa Soliman, Eman Ayman Nada, Jamal Ahmed, Hazem M Mazy, Israa Ahmed Qutob","doi":"10.1186/s12957-026-04535-9","DOIUrl":"10.1186/s12957-026-04535-9","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer surgeries remain the cornerstone of treatment for early-stage disease. Nonetheless, a substantial proportion of patients experience moderate-to-severe acute or chronic postoperative pain, adversely affecting quality of life and functional recovery. Regional anesthetic techniques have emerged as effective strategies for perioperative pain control. This study compares the erector spinae plane block (ESPB) and the thoracic paravertebral block (PVB) in breast cancer surgeries.</p><p><strong>Methods: </strong>Four databases were systematically searched for randomized controlled trials (RCTs) using ESPB and PVB in breast cancer surgeries. Primary extracted outcomes include post-operative morphine consumption, analgesia duration, resting and dynamic pain scores. Methodological quality was assessed using the ROB-2 tool, while data were pooled using the R software, Version 4.4.2.</p><p><strong>Results: </strong>Nineteen RCTs reporting on 1527 patients were included. Postoperative morphine consumption, PONV incidence, and intraoperative fentanyl use were comparable in both groups. Similarly, pain scores at rest and movement reported no significant differences. The two techniques also demonstrated similar results regarding the number of patients requiring rescue analgesia and analgesia duration. ESPB was associated with a significant, however clinically negligent, shorter surgery duration compared to PVB [MD -0.04, 95% CI; -0.07 to 0.00, P = 0.023].</p><p><strong>Conclusion: </strong>ESPB and PVB provide comparable analgesic efficacy and perioperative outcomes in breast cancer surgeries. ESPB may offer a shorter surgical duration, supporting its use as a simpler yet equally effective alternative to PVB, however this must be taken cautiously.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13499295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-infrared fluorescence imaging for ureteral and sentinel lymph node mapping in gynecological minimally invasive surgery: a review of fluorophores and domestic laparoscopic systems.","authors":"Tongxin Chen, Haili Li","doi":"10.1186/s12957-026-04516-y","DOIUrl":"10.1186/s12957-026-04516-y","url":null,"abstract":"<p><p>As laparoscopic techniques continue to advance, intraoperative tissue visualization has become increasingly important. In gynecological oncology, sentinel lymph node (SLN) mapping remains a critical procedure for assessing lymph node metastasis and guiding lymphadenectomy. Meanwhile, iatrogenic ureteral injury, although rare, can have severe consequences. Thus, achieving rapid, reliable, and cost-effective intraoperative visualization of both SLNs and the ureters during laparoscopy poses a significant clinical challenge. Near-infrared fluorescence (NIRF) imaging has emerged as a promising solution, using various fluorophores such as methylene blue (MB), indocyanine green (ICG), and technetium-99m (^99mTc) to enable clear visualization of living tissues. However, a comprehensive summary of the advantages and limitations of these fluorophores is lacking. This article reviews the efficacy of different fluorophores for SLN and ureteral mapping and discusses recent advances in domestic fluorescence laparoscopic systems.</p>","PeriodicalId":23856,"journal":{"name":"World Journal of Surgical Oncology","volume":"24 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}