Veterinary ophthalmology最新文献_第6页

Diurnal Variation of Intraocular Pressure, Central Corneal Thickness, and Ocular Surface Temperature in Van Cats. 眼内压、角膜中央厚度和眼表温度的日变化。

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-07-01 DOI: 10.1111/vop.70227

Mümin Gökhan Şenocak, Tuğçe Kartal, Şule Kaş, Çağlar Özkalipçi, Taner Arslan, Yasemin Akçora, Büşra Baykal, Cüneyt Türkmen, Sıtkıcan Okur, Ayşe Gölgeli Bedir, Uğur Ersöz

{"title":"Diurnal Variation of Intraocular Pressure, Central Corneal Thickness, and Ocular Surface Temperature in Van Cats.","authors":"Mümin Gökhan Şenocak, Tuğçe Kartal, Şule Kaş, Çağlar Özkalipçi, Taner Arslan, Yasemin Akçora, Büşra Baykal, Cüneyt Türkmen, Sıtkıcan Okur, Ayşe Gölgeli Bedir, Uğur Ersöz","doi":"10.1111/vop.70227","DOIUrl":"10.1111/vop.70227","url":null,"abstract":"Objective: This study aimed to evaluate the presence of diurnal variation in intraocular pressure (IOP), central corneal thickness (CCT), and ocular surface temperature (OST) in clinically healthy Van cats.Animals: Thirty-two clinically healthy Van cats.Methods: IOP, CCT, and OST were measured in the morning and afternoon in all cats. Paired measurements were obtained from each animal to assess diurnal changes. Differences between morning and afternoon measurements were analyzed using paired t-tests. Effect sizes were calculated using Cohen's d.Results: Mean morning IOP (25.22 ± 6.44 mmHg) was significantly higher than afternoon IOP (23.31 ± 6.50 mmHg) (t(63) = -2.29, p = 0.025). The mean difference was 1.91 mmHg (95% CI: 0.24-3.57 mmHg), corresponding to a small effect size (Cohen's d = 0.29). CCT showed no significant difference between morning and afternoon measurements (655.34 ± 71.10 μm vs. 648.33 ± 61.22 μm; p = 0.154), with a small effect size (Cohen's d = 0.18). Similarly, OST did not differ significantly between time points (35.90°C ± 0.60°C vs. 35.96°C ± 0.50°C; p = 0.603), and the effect size was negligible (Cohen's d = 0.06).Conclusion and clinical relevance: Van cats exhibited a small diurnal variation in IOP, whereas CCT and OST remained stable throughout the day. The magnitude of IOP fluctuation was minimal and may not be clinically relevant. These findings provide baseline physiological data for ocular parameters in Van cats and may assist clinicians in interpreting ophthalmic measurements obtained at different times of the day.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 4","pages":"e70227"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148398058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healing Outcomes and Complications of Spontaneous Chronic Corneal Epithelial Defects in French Bulldogs Following Diamond Burr Debridement and Bandage Contact Lens Placement Compared to a Population of Non-French Bulldogs. 与非法国斗牛犬相比，钻石毛刺清创和绷带隐形眼镜置入后法国斗牛犬自发性慢性角膜上皮缺损的愈合结果和并发症

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-07-01 DOI: 10.1111/vop.70201

James John Henry Bryan, Yvette Cherie Crowe, Kate Conway Robertson, Negar Hamzianpour, Kate Elizabeth Hindley, Kelly Lisa Yates, Francis Mark Billson

{"title":"Healing Outcomes and Complications of Spontaneous Chronic Corneal Epithelial Defects in French Bulldogs Following Diamond Burr Debridement and Bandage Contact Lens Placement Compared to a Population of Non-French Bulldogs.","authors":"James John Henry Bryan, Yvette Cherie Crowe, Kate Conway Robertson, Negar Hamzianpour, Kate Elizabeth Hindley, Kelly Lisa Yates, Francis Mark Billson","doi":"10.1111/vop.70201","DOIUrl":"10.1111/vop.70201","url":null,"abstract":"Objective: To compare age at diagnosis, procedure success and complications of spontaneous chronic corneal epithelial defects (SCCEDs) in French bulldogs compared with non-French bulldog breeds following diamond burr debridement and bandage contact lens placement (DBD/BCL).Method: A retrospective review identified dogs treated with DBD/BCL between January 2020 and December 2024 at multiple ophthalmology referral hospitals. Dogs with concurrent ocular or systemic disease that could impair corneal re-epithelialization were excluded. Data collected included signalment, time from diagnosis to DBD/BCL, prior treatments and medications, healing time, contact lens retention at the first follow-up, additional procedures required for healing, and complications.Results: A total of 332 SCCEDs from 288 dogs met the inclusion criteria: 119 SCCEDs from 100 French bulldogs and 213 SCCEDs from 188 other breeds. The mean age at diagnosis was 6.3 ± 1.7 years for French bulldogs and 8.9 ± 2.6 years for non-French bulldogs (p < 0.001). The median healing time following one DBD/BCL was 21 days (IQR: 15-34) for French bulldogs and 16 days (IQR: 14-21) for the comparison population (p < 0.001). Eighty-three percent (99/119) of French bulldogs healed after one DBD/BCL, compared to 89% (189/213) of non-French bulldogs (p = 0.153).Complications: corneal infection, subepithelial bullae formation, exuberant granulation tissue, and pigment deposition were statistically more common in French bulldogs (p < 0.001).Conclusion: French bulldogs develop SCCEDs at a younger age and experience longer healing times with increased complication rates following DBD/BCL compared to other breeds.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 4","pages":"e70201"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148017645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Ocular Surface Pathogen Susceptibility to Ultraviolet-C (UVC) Light Treatment With a Novel Prototype Device-An In Vitro Study. 用新型原型装置评价眼表病原菌对紫外线c （UVC）光处理的敏感性-体外研究

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-07-01 DOI: 10.1111/vop.70214

Oliver Joe Williams, Charlotte Dawson, Maria-Christine Fischer, Siân-Marie Frosini

{"title":"Assessment of Ocular Surface Pathogen Susceptibility to Ultraviolet-C (UVC) Light Treatment With a Novel Prototype Device-An In Vitro Study.","authors":"Oliver Joe Williams, Charlotte Dawson, Maria-Christine Fischer, Siân-Marie Frosini","doi":"10.1111/vop.70214","DOIUrl":"10.1111/vop.70214","url":null,"abstract":"Purpose: Assess in vitro efficacy of a device emitting 265 nm UVC light against bacteria isolated from veterinary infectious keratitis.Methods: Twenty-seven clinically-derived bacterial isolates: Staphylococcus pseudintermedius (n = 10; including n = 2 methicillin-resistant Staphylococcus pseudintermedius [MRSP]), Staphylococcus aureus (n = 1), Streptococcus canis (n = 4), Escherichia coli (n = 4, including n = 2 multidrug-resistant isolates), Pseudomonas aeruginosa (n = 7) and Serratia marcescens. (n = 1), and three type culture strains (n = 1 E. coli, S. aureus, S. pseudintermedius) were lawn cultured. Prototype UVC device (2.50 mW/cm2 intensity, 23 mm diameter beam) provided triplicate exposures at 1, 2, 3, and 5 s, and plates incubated (37°C, 16-20 h). All experiments were performed in duplicate (n = 6 treatment zones per timepoint, per isolate). Absence of growth in all exposed areas at any time demonstrated complete UVC inhibition; presence of growth was categorized as < 10 or ≥ 10 colonies.Results: UVC inhibition was complete in 11/30 isolates at ≤ 5 s exposure. Partial efficacy was seen in 18/19 remaining isolates at 5 s; ≥ 33% zones demonstrated absence of bacterial growth. Efficacy against MDR-MRSP and MDR-E. coli was comparable to susceptible counterparts. All P. aeruginosa were completely inhibited at ≤ 5 s; the S. marcescens isolate was least susceptible with ≥ 10 bacterial colonies within 50% zones after 5 s.Conclusion: Five seconds of UVC exposure is sufficient to markedly reduce growth of most bacterial species, including MDR-isolates and completely inhibit P. aeruginosa in vitro. These findings support further controlled in vivo safety and efficacy studies of UVC as an adjunct to topical antibiotics in companion animal infectious keratitis.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 4","pages":"e70214"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Evaluation of Smartphone-Based Fundus Imaging Systems in Dogs and Cats. 基于智能手机的狗和猫眼底成像系统的比较评估。

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-07-01 DOI: 10.1111/vop.70210

Bertrand Michaud

{"title":"Comparative Evaluation of Smartphone-Based Fundus Imaging Systems in Dogs and Cats.","authors":"Bertrand Michaud","doi":"10.1111/vop.70210","DOIUrl":"10.1111/vop.70210","url":null,"abstract":"Objective: To compare the feasibility, image quality, acquisition time, and evaluator preference of four smartphone-based fundus imaging (SBFI) systems in dogs and cats using a handheld fundus camera as a reference device.Animals studied: Twenty client-owned animals, including 10 dogs and 10 cats.Procedures: Fundus images were obtained from 40 eyes (20 mydriatic and 20 non-mydriatic) using four SBFI systems (iExaminer Panoptic, NUN WFE-02S, OQVet, and VistaView) and a handheld infrared fundus camera (Aurora). Image acquisition success and acquisition time were recorded for each device. Image quality was independently graded using a 10-point Likert scale by a masked panel of 32 veterinary ophthalmologists. Evaluators also selected their preferred image among the four SBFI systems.Results: Image acquisition was successful in all animals for all devices under both mydriatic and non-mydriatic conditions (100%). Image quality differed significantly between devices. Among SBFI systems, OQVet achieved the highest median score (7; interquartile range [IQR] 6-8), followed by VistaView (6; IQR 5-8), NUN (5; IQR 4-7), and iExaminer (4; IQR 3-5). OQVet received approximately 50% of evaluator preference votes. The reference camera achieved the highest image quality in 77.5% of imaging sets but was outperformed by OQVet (15%) and VistaView (7.5%) in some examinations. Pupil dilation did not significantly influence image quality or acquisition time.Conclusions: Smartphone-based fundus imaging enables reliable retinal imaging in dogs and cats and represents an accessible option for retinal documentation and screening in veterinary practice.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 4","pages":"e70210"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13255162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148219877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular Manifestations in Dogs With Facial Nerve Dysfunction. 面神经功能障碍犬的眼部表现。

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-07-01 DOI: 10.1111/vop.70219

L Gaztelu, M Leiva, T Peña, J Ríos

{"title":"Ocular Manifestations in Dogs With Facial Nerve Dysfunction.","authors":"L Gaztelu, M Leiva, T Peña, J Ríos","doi":"10.1111/vop.70219","DOIUrl":"10.1111/vop.70219","url":null,"abstract":"Objective: To characterize the spectrum and frequency of ocular abnormalities associated with facial nerve dysfunction (FND) in dogs and to assess clinical outcomes, with specific comparison between brachycephalic (BC) and non-brachycephalic (NBC) breeds: METHODS: Medical records of dogs with FND evaluated between 2009 and 2023 at the Ophthalmology Service of the Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, were retrospectively reviewed.Results: Seventy-four dogs (84 eyes) were included, with French Bulldog being the most frequently affected breed (20; 27.0%). Facial nerve paralysis affected 63.1% of eyes, whereas paresis affected 36.9%. The main etiologies were idiopathic (14.9%), iatrogenic (13.5%), and otitis media/interna (12.2%). Corneal sensitivity and Schirmer tear test I were significantly reduced in affected eyes, without significant differences between skull types. Ulcerative keratitis occurred in 61.9% of eyes, being more frequent and severe in BC dogs (p = 0.007). Facial function recovered in 47.6% of dogs. Recovery was unaffected by age or skull type, differed significantly by sex (p = 0.043), and tended to be higher in dogs with paresis (p = 0.075). Worse ocular outcomes were linked to lower esthesiometry values (p = 0.023) and to the presence of anterior uveitis (p = 0.037). At the end of the study, 14 eyes (17.6%) were enucleated.Conclusions: FND carries a guarded prognosis in dogs, with fewer than half achieving functional recovery. Ocular surface disorders, particularly neurogenic keratoconjunctivitis sicca and neuroparalytic ulcerative keratitis, were frequent and often led to poor outcomes, especially in BC dogs. Early ophthalmic management is crucial to preserve vision.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 4","pages":"e70219"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adult Equine Optic Nerve Head Measurements Using Spectral Domain Optical Coherence Tomography. 使用光谱域光学相干断层扫描测量成年马视神经头。

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-05-01 DOI: 10.1111/vop.70174

Hannah N Bostick, Deborah A Keys, Anna Catherine Bowden, Richard J McMullen

{"title":"Adult Equine Optic Nerve Head Measurements Using Spectral Domain Optical Coherence Tomography.","authors":"Hannah N Bostick, Deborah A Keys, Anna Catherine Bowden, Richard J McMullen","doi":"10.1111/vop.70174","DOIUrl":"10.1111/vop.70174","url":null,"abstract":"Purpose: To compare equine optic nerve head (ONH) measurements using spectral domain optical coherence tomography (SD-OCT) to detect clinically relevant ONH cupping.Methods: Forty-five eyes from 34 horses were categorized as CONTROL or CUPPED based on indirect ophthalmoscopy and were measured using SD-OCT: Bruch's membrane opening (BMO), optic cup width (OC), anterior laminar depth (ALD), prelaminar thickness (PLT), and cup-to-disk ratio (OC: BMO) at superior (sup.), central (ctr.), and inferior (inf.) ONH locations.Results: The OC:BMO was 0.61 ± 0.09 (sup.), 0.64 ± 0.09 (ctr.), and 0.55 ± 0.10 (inf.) (CONTROL), and 0.60 ± 0.09 (sup.), 0.62 ± 0.08 (ctr.) and 0.54 ± 0.10 (inf.) (CUPPED). The ALD was 0.48 ± 0.20 mm (sup.), 0.50 ± 0.20 mm (ctr.), and 0.42 ± 0.18 mm (inf.) (CONTROL), and 0.49 ± 0.16 mm (sup.), 0.57 ± 0.20 mm (ctr.), and 0.46 ± 0.16 mm (inf.) (CUPPED). The PLT was 0.22 ± 0.08 mm (sup.), 0.17 ± 0.08 mm (ctr.), and 0.17 ± 0.05 mm (inf.) (CONTROL), and 0.21 ± 0.05 mm (sup.), 0.18 ± 0.04 mm (ctr.), and 0.18 ± 0.05 mm (inf.) (CUPPED). The ctr. BMO was significantly increased (mean ± SD of 4.19 ± 0.52 mm) compared to CONTROL (ctr. p = 0.007) eyes.Conclusions: Equine ONHs suggestive of clinical optic nerve head cupping had similar degrees of ONH depression to CONTROL eyes using SD-OCT. Clinical signs such as a prominent lamina cribrosa, ONH pallor, and retinal vascular attenuation may not be reliable predictors of equine ONH cupping. Further research is necessary to determine accurate clinical signs associated with ONH cupping.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 3","pages":"e70174"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immediate Effect of Three Artificial Tear Formulations on Tear Film Osmolality in Brachycephalic Dogs. 三种人工泪液配方对短头畸形犬泪膜渗透压的直接影响。

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-05-01 DOI: 10.1111/vop.70177

Houman Faghihi, Seyed Mehdi Rajaei

{"title":"Immediate Effect of Three Artificial Tear Formulations on Tear Film Osmolality in Brachycephalic Dogs.","authors":"Houman Faghihi, Seyed Mehdi Rajaei","doi":"10.1111/vop.70177","DOIUrl":"10.1111/vop.70177","url":null,"abstract":"Purpose: To investigate the effects of three sodium hyaluronate-based artificial tear formulations on tear film osmolality (TFO) in brachycephalic dogs.Animals: Forty healthy brachycephalic dogs were evaluated.Procedure(s): TFO was measured using the I-PEN VET osmometry system. Dogs were assigned to four groups. Dogs in Groups 1, 2, and 3 received one drop of artificial tear containing 0.4% sodium hyaluronate, artificial tear containing 0.9 mg sodium hyaluronate and vitamin B12 in 0.5 mL, and artificial tear containing 1.6 mg hyaluronate in 0.5 mL, respectively. Dogs in Group 4 served as controls and received one drop of sterile water for injection. Tear osmolality was measured 10 min after instillation of the eye drop. Statistical analysis was performed using SPSS software.Results: Mean (SD) TFO at the initial examination was 307.4 (35.8), 299.4 (12.0), 318.2 (34.3), 307.2 (12.0) mOsm/L in Groups 1-4, respectively. Ten minutes after instillation of artificial tears, TFO was decreased by 53.4 mOsm/L (17.3%), 17.6 mOsm/L (5.8%), 31.8 mOsm/L (9.9%) and 3.4 mOsm/L (1.1%), respectively. Significant decreases were observed in Groups 1-3 (p = 0.016, 0.021, 0.038). Intergroup comparison revealed significant differences in mean TFO between Groups 1 and 4 (p = 0.006).Conclusions and clinical relevance: This study demonstrated a significant immediate reduction of TFO with HA containing artificial tears in brachycephalic dogs. Artificial tears containing 2 mg of sodium hyaluronate in 0.5 mL (0.4%) had the most significant effect. Further studies are warranted in a large group of dogs with dry eye disease.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 3","pages":"e70177"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147639924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features of Optical Coherence Tomography (OCT) in a Case of Chronic Uveodermatologic Syndrome. 1例慢性葡萄膜皮肤病综合征的光学相干断层扫描（OCT）特征。

IF 1.3 4区农林科学

Veterinary ophthalmology Pub Date : 2026-05-01 DOI: 10.1111/vop.70183

Alexa P Gray, Eric C Ledbetter, Jeanine Peters-Kennedy, Ryan Taylor, Erin M Scott

{"title":"Features of Optical Coherence Tomography (OCT) in a Case of Chronic Uveodermatologic Syndrome.","authors":"Alexa P Gray, Eric C Ledbetter, Jeanine Peters-Kennedy, Ryan Taylor, Erin M Scott","doi":"10.1111/vop.70183","DOIUrl":"10.1111/vop.70183","url":null,"abstract":"Objective: To report retinal optical coherence tomography (OCT) findings in a dog with chronic uveodermatologic syndrome (UDS) and to correlate these findings with clinical features to aid in diagnosis.Animal studied: A 7-year-old spayed female mixed-breed dog presented with red eyes and suspected vision loss. She had a history of panuveitis and bilateral bullous retinal detachments diagnosed 3 years earlier.Methods: Complete ophthalmic examination was performed to evaluate active anterior uveitis and inactive chorioretinitis. Physical exam revealed new vitiligo and skin biopsies of the nasal planum and eyelids confirmed a diagnosis of UDS by a dermatopathologist. Fundus photography documented the retinal lesions and OCT characterized the changes to retinal structure. GLS-1027, a novel anti-inflammatory medication, was started after the most recent flare up in an attempt to control future flare ups.Results: RetCam fundus photography revealed well-demarcated areas of tapetal hyperreflectivity, hyperpigmented scarring, and non-tapetal depigmentation. OCT b-scans revealed normal retinal layering in unaffected areas and marked pathologic changes in affected areas. These changes included diffuse structural alteration of the retina in areas of hyperpigmented scarring and hypopigmented regions with partial-to-complete loss of retinal thickness and structure. 12 months after the last recheck, the dog continued to receive oral GLS-1027 and had no recurrence of clinical signs on ocular exam.Conclusions: This study represented the first documentation of in vivo retinal changes in UDS using OCT imaging. This case highlighted the potential of OCT to visualize retinal changes in UDS and suggests its possible utility in disease monitoring.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 3","pages":"e70183"},"PeriodicalIF":1.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Light Intensity on the Geometric Iridocorneal Angle and Ciliary Cleft Parameters Using Ultrasound Biomicroscopy in Normal Purpose-Bred Beagle Dogs. 超声生物显微镜下光强对普通比格犬虹膜角膜几何角和睫状体裂隙参数的影响

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-05-01 DOI: 10.1111/vop.70184

Kelsey E Cornman, Diane Van Horn Hendrix, Xiaojuan Zhu, Braidee C Foote

{"title":"Effect of Light Intensity on the Geometric Iridocorneal Angle and Ciliary Cleft Parameters Using Ultrasound Biomicroscopy in Normal Purpose-Bred Beagle Dogs.","authors":"Kelsey E Cornman, Diane Van Horn Hendrix, Xiaojuan Zhu, Braidee C Foote","doi":"10.1111/vop.70184","DOIUrl":"10.1111/vop.70184","url":null,"abstract":"Objective: To evaluate the effect of varying light intensity on geometric iridocorneal angle (ICA) and ciliary cleft (CC) parameters using ultrasound biomicroscopy (UBM) in normal canines.Animals studied: Twenty clinically normal adult purpose-bred Beagles (40 eyes).Procedures: All dogs underwent UBM of the CC at two locations (dorsal and temporal) in each eye under dark (< 1 lx), dim (~40 lx), and bright (> 1500 lx) light conditions. The following parameters were measured: geometric ICA, width of CC entrance, width of mid-CC, and length of CC. Digital color and infrared photographs were obtained to allow for pupil diameter measurement under each light condition.Results: Increasing light intensity resulted in significant decrease in the geometric ICA (dark: 47.27° ± 11.09°; dim: 40.48° ± 9.71°; bright: 26.72° ± 7.63°; p = 0.0001) with marginal effect on the width of CC entrance (dark: 0.25 ± 0.04 mm; dim: 0.27 ± 0.06 mm; bright: 0.28 ± 0.08 mm; p = 0.0548), and no effect on width of mid-CC, or length of CC. Regardless of light intensity or laterality of eye, geometric ICA and width of CC entrance were significantly greater dorsally (ICA: 39.82° ± 12.67° dorsal vs. 36.5° ± 12.8° temporal; CC entrance: 0.28 ± 0.07 mm dorsal vs. 0.26 ± 0.06 mm temporal; p = 0.0003 respectively) and CC length was significantly greater temporally (2.36 ± 0.28 mm temporal vs. 2.2 ± 0.27 mm dorsal; p = 0.0028).Conclusions: Aside from the geometric ICA, varying light intensity does not significantly impact CC measurements. ICA and CC measurements varied by quadrant. The authors recommend performing UBM of the CC in dim light conditions as this is most applicable to clinical settings and subjectively provided the greatest image quality.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 3","pages":"e70184"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs. 未麻醉健康犬角膜内皮成像技术的比较。

IF 1.1 4区农林科学

Veterinary ophthalmology Pub Date : 2026-05-01 DOI: 10.1111/vop.70182

Hyunwoo Suk, Minju Kim, Dohyeong Kim, Seonmi Kang, Kangmoon Seo

{"title":"Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs.","authors":"Hyunwoo Suk, Minju Kim, Dohyeong Kim, Seonmi Kang, Kangmoon Seo","doi":"10.1111/vop.70182","DOIUrl":"10.1111/vop.70182","url":null,"abstract":"Objective: To compare unsedated noncontact specular microscopy imaging techniques for the canine corneal endothelium and identify the most effective technique.Animals studied: Nineteen eyes of 10 systemically healthy, staff-owned dogs with clinically normal corneas were studied.Procedure: Six imaging groups were divided according to the different techniques used in all eyes: central focusing, with (CP) or without (CN) induction of an indirect pupillary light reflex (PLR); peripheral focusing with (PP) or without (PN) an indirect PLR; PP with application of a contact lens (CL); and gaze fixation with a treat (GF). The success rates, imaging times, and endothelial cell indices were compared.Results: Success rates differed significantly among the techniques, with PP and CL achieving significantly higher success rates than CN. When only successful images were analyzed, the mean imaging time showed no statistically significant differences between the groups. In the sensitivity analysis, PP required significantly shorter imaging times than CN and PN. The Endothelial cell indices (cell count, endothelial density, and hexagonality) did not differ significantly among the techniques.Conclusions: Peripheral focusing combined with the induction of an indirect PLR (PP) achieved significantly higher success rates and shorter imaging times than other techniques, suggesting that this technique provides the most reliable and efficient approach for evaluating the canine corneal endothelium with noncontact specular microscopy under unsedated conditions.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":"29 3","pages":"e70182"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13090425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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