Veterinary ophthalmology最新文献_第10页

Ocular findings in dogs and cats following chemical injury by the Bronze Orange Bug (Musgraveia sulciventris). 被铜橙虫（Musgraveia sulciventris）化学伤害后狗和猫的眼部发现。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-12-12 DOI: 10.1111/vop.13308

Kelly Lisa Yates, Kate Conway Robertson, Yvette Cherie Crowe, Francis Mark Billson

{"title":"Ocular findings in dogs and cats following chemical injury by the Bronze Orange Bug (Musgraveia sulciventris).","authors":"Kelly Lisa Yates, Kate Conway Robertson, Yvette Cherie Crowe, Francis Mark Billson","doi":"10.1111/vop.13308","DOIUrl":"https://doi.org/10.1111/vop.13308","url":null,"abstract":"Objective: To describe the ocular findings in dogs and cats after chemical injury by the Bronze Orange Bug (Musgraveia sulciventris), which is endemic to eastern Australia in Queensland and New South Wales.Animals studied: Medical records were reviewed for the keywords \"stink bug\" between February 2013 and January 2023. Signalment, clinical signs, month at presentation, and affected eye(s) were recorded. Cases were divided into confirmed and suspected cases.Results: Twenty-four confirmed and nine suspected cases were identified, consisting of 26 dogs and seven cats. There were 19 females (57.6%) and 14 males (42.4%). Median age at presentation was 1.9 (range 0.16-12.5) years, with a median weight of 6.1 (range 1.3-25) kilograms. All cases presented between August and May, with the majority (75.7%) presenting in summer. This correlates with the breeding life cycle of the Bronze Orange Bug. Unilateral presentation was more common (97%; n = 32) than bilateral (3%; n = 1) with an increased incidence of left eyes (60.6%; n = 20) compared to right eyes (36.4%; n = 12). Presenting signs included acute onset blepharospasm (100%), superficial corneal ulceration (90.9%), conjunctival hyperemia (87.8%), chemosis (60.6%), periocular swelling (51.5%), conjunctival ulceration (39.4%), third eyelid protrusion (39.4%), miosis (36.4%), corneal edema (36.4%), and aqueous flare (24.2%). The median time to resolution of clinical signs was 13 days.Conclusions: The Bronze Orange Bug's defensive secretion causes acute onset ocular irritation consistent with acidic chemical burns in dogs and cats. Bronze Orange Bug exposure should be considered as a differential diagnosis in endemic areas, particularly during the summer months.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Keratoconjunctivitis sicca in intact Aksaray Malakli breed dogs: Evaluation of 50 cases. 完整Aksaray Malakli犬的干枯性角膜结膜炎：50例评价。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-12-11 DOI: 10.1111/vop.13298

Nihan Avci, Fehmiye Gumus, Basak Boztok Ozgermen, Dogukan Ozen

{"title":"Keratoconjunctivitis sicca in intact Aksaray Malakli breed dogs: Evaluation of 50 cases.","authors":"Nihan Avci, Fehmiye Gumus, Basak Boztok Ozgermen, Dogukan Ozen","doi":"10.1111/vop.13298","DOIUrl":"https://doi.org/10.1111/vop.13298","url":null,"abstract":"Objectives: Keratoconjunctivitis sicca (KCS) is characterized by decreased aqueous tear film components, leading to ocular surface damage. Diagnosis involves clinical examination, Schirmer Tear Test (STT1), and Tear Film Break-Up Time (TFBUT) measurement. This retrospective study aimed to assess dry eye syndrome in intact, purebred, Aksaray Malakli breed dogs, and investigate potential associations with hereditary ocular diseases due to inbreeding for phenotype preservation.Animals: Fifty healthy, purebred, intact Aksaray Malakli dogs of varying ages and sexes, all exhibiting conjunctival hyperemia and mucoid ocular discharge. Dogs with chronic diseases, systemic medication, or ongoing ophthalmic treatment were excluded.Procedures: Demographic data, ophthalmic examination results, and ocular anomalies were recorded. STT1 and TFBUT assessments were performed to measure tear production and film stability. STT1 values were scored from 1 (normal) to 4 (severe dry eye), and TFBUT ≥20 s was considered normal. Statistical analyses were used to evaluate correlations and differences.Results: The correlation between age and STT1 values (r = -.182, p = .206) was not statistically significant. Mean STT1 was higher in females than males, though not significantly (p = .849). Dogs without third eyelid gland prolapse had significantly higher STT1 and TFBUT measurements compared to those with prolapse (p = .027). No significant sex difference was found in the frequency of third eyelid prolapse (p = .289). A significant positive correlation was observed between STT1 and TFBUT (r = .924; p < .001).Conclusions: Aksaray Malakli dogs, particularly those with third eyelid gland prolapse, are predisposed to mild to moderate KCS. These findings suggest the need for further clinical and genetic investigations to better understand and manage dry eye syndrome in this breed.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gender differences in canine anterior chamber dimensions: Potential implications for primary angle-closure glaucoma. 犬前房尺寸的性别差异：原发性闭角型青光眼的潜在影响。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-12-06 DOI: 10.1111/vop.13303

Donghee Kim, Hyun Kwon, Jiyi Hwang, Ji Seung Jung, Myeongjee Kwon, Jungyeon Yong, Haerin Yoon, Soohyun Kim, Kyung-Mee Park

{"title":"Gender differences in canine anterior chamber dimensions: Potential implications for primary angle-closure glaucoma.","authors":"Donghee Kim, Hyun Kwon, Jiyi Hwang, Ji Seung Jung, Myeongjee Kwon, Jungyeon Yong, Haerin Yoon, Soohyun Kim, Kyung-Mee Park","doi":"10.1111/vop.13303","DOIUrl":"https://doi.org/10.1111/vop.13303","url":null,"abstract":"Objectives: This study aimed to explore anatomical differences in the aqueous humor (AH) outflow pathway between male and female dogs using ultrasound biomicroscopy (UBM).Animals studied: Clinical data were collected from 30 eyes of 30 dogs (15 males: 10 right eyes, 5 left eyes; and 15 females: 7 right eyes, 8 left eyes) treated at the Veterinary Medical Teaching Hospital of Chungbuk National University, South Korea, between August 2018 and February 2024.Procedure: The study conducted an in-depth UBM examination, specifically observing peripheral anterior chamber depth (ACD), geometric iridocorneal angle (ICA), and angle-opening distance (AOD) alongside measurements of ciliary cleft width (CCW), length (CCL), and area (CCA), and assessed the longitudinal fibers of ciliary muscle thickness (Lf-CMT) and the longitudinal and radial fibers of ciliary muscle thickness (LRf-CMT) for gender-based differences.Results: The study identified a significant sex difference in peripheral ACD, with females displaying shallower depths compared to males, potentially clarifying the higher incidence of glaucoma in female dogs. No significant gender differences were found in ICA, AOD, CC parameters, or ciliary muscle parameters measurements.Conclusion: This research uncovered that peripheral ACD is significantly shallower in females than in males, potentially indicating a risk factor that could contribute to the development of primary angle-closure glaucoma.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse iris melanoma leading to secondary glaucoma in a lion (Panthera leo)-A case report. 狮子（Panthera leo）弥漫性虹膜黑色素瘤导致继发性青光眼1例报告。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-12-01 DOI: 10.1111/vop.13307

Jade Caproni Correa, Matheus Vilardo Lóes Moreira, Manoel Lucas Javorouski, Juliana Werner, Gillian Shaw, Barbara Schreider, Ricardo Guilherme D'Otaviano de Castro Vilani, Fabiano Montiani-Ferreira

引用次数: 0

Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes. 118例猫眼和9例狗眼感染的回顾性研究。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-11-28 DOI: 10.1111/vop.13301

Sophie Hofmann-Wellenhof, Barbara Nell

{"title":"Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes.","authors":"Sophie Hofmann-Wellenhof, Barbara Nell","doi":"10.1111/vop.13301","DOIUrl":"https://doi.org/10.1111/vop.13301","url":null,"abstract":"Purpose: This study aims to inform about the clinical image, diagnostic possibilities, and treatment options for cats and dogs diagnosed with ocular encephalitozoonosis.Materials and methods: Medical records of 7 dogs and 75 cats with ocular encephalitozoonosis presented at the Clinical Unit of Ophthalmology of the University of Veterinary Medicine Vienna between 08/2006 and 02/2022 have been compiled. Diagnosis was based on the presence of cataracts and positive antibody titer against Encephalitozoon cuniculi. Patient history, details on the characteristics of the cataracts, level of antibody titers, and the treatment regimen were summarized, as are the results of histological stainings of surgical samples to determine the presence of Encephalitozoon cuniculi, as well as PCR analyses to identify its sub-strains.Results: Our analysis of the clinical data shows that focal cortical anterior cataracts often associated with anterior uveitis and lesions in the fundus are the most prevalent manifestation of ocular encephalitozoonosis in cats and dogs.Conclusion: Serological testing and PCR analysis of lens material are the most important diagnostic tools. Timely phacoemulsification with adjuvant anti-inflammatory and antiparasitic medication is the most promising therapy for Encephalitozoon cuniculi-induced cataracts.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of 0.024% latanoprostene bunod on intraocular pressure and pupil diameter in normal cats and cats with congenital glaucoma. 0.024%拉坦前列腺素对正常猫和先天性青光眼猫眼压和瞳孔直径的影响。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-11-28 DOI: 10.1111/vop.13302

Vanessa Y Yang, J Seth Eaton, Julie A Kiland, Kelly E Koch, Kazuya Oikawa, Scott J Hetzel, Gillian J McLellan

{"title":"Effects of 0.024% latanoprostene bunod on intraocular pressure and pupil diameter in normal cats and cats with congenital glaucoma.","authors":"Vanessa Y Yang, J Seth Eaton, Julie A Kiland, Kelly E Koch, Kazuya Oikawa, Scott J Hetzel, Gillian J McLellan","doi":"10.1111/vop.13302","DOIUrl":"10.1111/vop.13302","url":null,"abstract":"Objective: To evaluate the effects of latanoprostene bunod on intraocular pressure (IOP) and pupil diameter (PD) in normal cats and cats with feline congenital glaucoma (FCG).Animals studied: Five normal and 5 FCG cats.Procedures: This masked, controlled crossover study comprised a 1-day Pre-treatment phase followed by two 10-day Treatment phases, each followed by a 10-day Recovery phase. During treatment, all cats received twice daily 0.005% latanoprost (LAT) or 0.024% latanoprostene bunod (LBN) in a randomized eye. Following Recovery, the same eye was treated with the opposite drug. Contralateral eyes served as saline-treated controls. Intraocular pressure and PD measurements were performed three times daily during all study phases. Data were analyzed via constrained longitudinal data analysis models.Results: Neither drug significantly reduced IOP in normal cats. In FCG cats, statistically significant reductions in mean (95% CI) IOP were observed relative to controls 4 h after LAT and LBN treatment (-5.5 mmHg [-8.4, -2.5], p < .001, -7.2 mmHg [-10.2, -4.3], p < .001, respectively). These differences represented 28.4% and 37.9% IOP reductions, respectively. Mean IOP reduction after 4 h was significantly greater with LBN treatment compared to LAT (-1.8 mmHg [-3.2, -0.4], p = .012). However, these IOP reductions were not considered clinically significant. Both drugs similarly reduced PD in normal and FCG cats.Conclusions: Transient IOP reduction was observed after topical administration of LAT and LBN in FCG cats; and mean IOP difference was statistically significantly greater in LBN-treated eyes. However, the apparent enhanced hypotensive effect of LBN is not clinically significant.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-fibrotic effects of lisinopril (ACE inhibitor) and fasudil (ROCK inhibitor) in combination for canine corneal fibrosis in vitro. 利辛普利（ACE 抑制剂）和法舒地尔（ROCK 抑制剂）联用对犬角膜纤维化的体外抗纤维化作用。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-11-26 DOI: 10.1111/vop.13304

Brayden L Routh, Ratnakar Tripathi, Elizabeth Giuliano, Payton Lujin, Prashant R Sinha, Rajiv R Mohan

{"title":"Anti-fibrotic effects of lisinopril (ACE inhibitor) and fasudil (ROCK inhibitor) in combination for canine corneal fibrosis in vitro.","authors":"Brayden L Routh, Ratnakar Tripathi, Elizabeth Giuliano, Payton Lujin, Prashant R Sinha, Rajiv R Mohan","doi":"10.1111/vop.13304","DOIUrl":"10.1111/vop.13304","url":null,"abstract":"Background: Corneal fibrosis is a leading cause of blindness in mammalian species and may result in compromised performance in sports and daily functions. This study evaluated the safety and anti-fibrotic effects of the FDA-approved drugs, angiotensin-converting enzyme inhibitor (ACE-I) lisinopril and rho-kinase inhibitor (ROCK-I) fasudil, alone and in combination, on the canine cornea using an established in vitro model.Methods: To test the safety and efficacy of lisinopril and fasudil, primary canine corneal fibroblasts (CCFs) generated from donor corneas of healthy dogs (n = 20) were used. A series of dose-dependent and time-dependent assays with lisinopril (1-50 μM) and fasudil (1-10 nM) were performed. qRT-PCR, immunofluorescence (IF) staining, cell viability assay, cell proliferation assay, LIVE/DEAD viability/cytotoxicity assay, TUNEL assay, and total cell count were performed.Results: A 25-μM lisinopril and 3-nM fasudil dose were safe, nontoxic, and optimal for therapeutic evaluations in vitro. Treatments of lisinopril or fasudil, alone or in-combination, to CCFs grown in the presence of TGF-β1 (5 ng/mL) showed inhibition of myofibroblast formation based on phase-contrast microscopy. The qRT-PCR and IF studies showed a significant decrease in expression of profibrotic markers, including α-smooth muscle actin (α-SMA; p < .0001), fibronectin (FN; p = .0002), tenascin C (TNC; p < .0001), Collagen I (Col-I; p < .0001), Collagen IIIA1 (Co-IIIA1; p < .0001), and Collagen IV (Co-lV; p < .0001).Conclusion: An ophthalmic formulation consisting of lisinopril and fasudil may offer a safe and effective method to treat canine corneal fibrosis. Additional studies evaluating safety and efficacy of this formulation in vivo are warranted.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights from an online survey: Veterinary surgeons' antibiotic practices in ophthalmic surgery in Germany. 在线调查的启示：德国兽医在眼科手术中使用抗生素的情况。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-11-11 DOI: 10.1111/vop.13300

Claudia Busse, Anne Raab, Lothar Kreienbrock, Holger Andreas Volk

{"title":"Insights from an online survey: Veterinary surgeons' antibiotic practices in ophthalmic surgery in Germany.","authors":"Claudia Busse, Anne Raab, Lothar Kreienbrock, Holger Andreas Volk","doi":"10.1111/vop.13300","DOIUrl":"https://doi.org/10.1111/vop.13300","url":null,"abstract":"Purpose: To investigate antibiotic usage practices in ophthalmic surgeries in Germany.Materials and methods: An online questionnaire was sent to veterinary surgeons (general veterinarians and veterinarians with additional qualification in ophthalmology) inquiring about their antibiotic preferences, administration methods, and factors affecting antibiotic usage in ophthalmic surgical procedures.Results: A total of 417 questionnaires were analyzed. Postoperative antibiotics (systemic/topical in percent when used) were used all or most of the time by 69% of veterinarians following enucleation (99/6), by 62% after eyelid surgery (54/69), by 68% after third eyelid (TEL) surgery (19/92) and by 80% after keratectomy (6/99). The most commonly used systemic antibiotic was amoxicillin with clavulanic acid and the most commonly used topical antibiotic was chloramphenicol. WHO \"watch-group\" antibiotics were infrequently administered systemically but frequently utilized topically; including in 13% of eyelid surgery, 15% of TEL surgery, and 35% of keratectomies. Factors influencing antibiotic use included fear of complications (67%), personal experience (63%), diagnostic uncertainty (21%), and owner expectations (9%). Participants following institutional guidelines used fewer antibiotics in enucleations (p = .002) and were less likely to choose fluoroquinolones post-eyelid surgery (p = .044).Conclusion: The potential for reducing antibiotic use following ophthalmic soft tissue surgery is significant. Addressing barriers such as concerns about postoperative complications and the reliance on individual clinical experience, the implementation of standardized guidelines could facilitate a shift toward more judicious antibiotic practices.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of meibomian gland morphology and tear-film lipid layer using noncontact infrared meibography and meibometry, respectively, and tear-film osmolarity in healthy dogs. 分别使用非接触式红外睑板腺造影术和睑板腺测定法评估健康狗的睑板腺形态和泪膜脂质层以及泪膜渗透压。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-11-11 DOI: 10.1111/vop.13294

Alexandra T J Ng, Phillip Anthony Moore, Shannon D Boveland

{"title":"Assessment of meibomian gland morphology and tear-film lipid layer using noncontact infrared meibography and meibometry, respectively, and tear-film osmolarity in healthy dogs.","authors":"Alexandra T J Ng, Phillip Anthony Moore, Shannon D Boveland","doi":"10.1111/vop.13294","DOIUrl":"https://doi.org/10.1111/vop.13294","url":null,"abstract":"Objective: To further investigate quantitative and qualitative tear-film dynamics through tear-film osmolarity, meibometry, meibography, and non-invasive tear-film break-up time and to describe a survey of parameters in normal eyes of healthy non-brachycephalic dogs.Animals studied: Thirty-two veterinary hospital staff and student owned dogs between 1 and 7 years with no known comorbidities or ocular disease.Procedure: Complete ophthalmic examination, tear-film osmolarity (I-PEN® VET), meibometry (Meibometer MB560), meibography, and non-invasive tear-film break-up time (handheld Ocular Surface Analyzer) were performed. Significance threshold was 0.05. Q-Q plots and histograms were used to assess normality of measurements. Data were summarized descriptively with mean, standard deviation, median, and interquartile range (IQR). Pearson and Spearman's correlations were used to test for correlations between diagnostics with each other and tear-film break-up times.Results: Thirty-two dogs (64 eyes) met the inclusion criteria. Mean tear-film osmolarity level was 293.6 ± 14.1 mOsm/L (IQR 282.5-302.3). Median meibomian lipid level was 30.4 Meibometry Units (MU) (IQR 11.5-59.1). Median percent loss of meibomian glands in the upper eyelids was 25.3% (IQR 13.5-26.8). Median percent loss of meibomian glands in the lower eyelids was 26.0% (IQR 13.5-52.3). Automatic assessment of meibomian gland loss showed that grade 0 was present in 4/128 (3.1%) eyelids, grade 1 in 78/128 (60.9%) eyelids, grade 2 in 30/128 (23.4%) eyelids, and grade 3 in 16/128 (12.5%) eyelids.Conclusions: Tear-film osmolarity, meibometry, meibography, and non-invasive tear break-up time can easily be incorporated into routine ophthalmic examinations to provide clinical information about meibomian gland morphology and function.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of scleral rupture of canine globes following compression via mechanical testing unit. 通过机械测试装置检测犬球受压后巩膜破裂的特征。

IF 1.7 4区农林科学

Veterinary ophthalmology Pub Date : 2024-11-07 DOI: 10.1111/vop.13299

Jennifer Goldreich, Diane Hendrix, Pierre-Yves Mulon, Daniel Ward

{"title":"Characterization of scleral rupture of canine globes following compression via mechanical testing unit.","authors":"Jennifer Goldreich, Diane Hendrix, Pierre-Yves Mulon, Daniel Ward","doi":"10.1111/vop.13299","DOIUrl":"https://doi.org/10.1111/vop.13299","url":null,"abstract":"Purpose: To determine the load at failure of canine intact cadaveric eyes and to describe the anatomic location and length of the rupture following external compression.Animals studied: Sixty-six canine cadaveric globes.Procedures: Globes were subjected to an axial force impacting the cornea or equator using a commercially available mechanical testing unit. Following rupture, eyes were inspected to document the anatomical site and length of rupture.Results: The mean ± SD force necessary to induce scleral rupture was 310 ± 120 N OD and 294 ± 113 N OS. Increasing body weight (OD p = .000015, OS p = .0074) as well as cranial-to-caudal (OD p = .000045, OS p = .0075) and medial-to-lateral (OD p = .00027, OS p = .0083) globe diameter were associated with a higher force necessary to induce rupture. The median (25%, 75%) length of the scleral rupture was 8.5 (7.0, 11.0) mm OS and 10 (7.0, 12.5) mm OD. The median location was 8.0 (5.0, 10.0) mm posterior to the limbus at the most cranial extent OS and 6.5 (3.3, 10.0) mm OD. Rupture orientation in relation to the limbus was perpendicular (n = 35), parallel (n = 13), or other (n = 16). Globe laterality (i.e., OD or OS), sex, and age did not have a significant influence on the force necessary to induce rupture (p > .05).Conclusions: Following external compression, the canine globe frequently ruptures in a region approximating the equator extending 1 cm posteriorly, which may not be readily apparent on clinical examination.","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0