Veterinary ophthalmology最新文献

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In Vivo Confocal Microscopy Features of Corneal Dystrophy in Siberian Huskies. 西伯利亚哈士奇角膜营养不良的体内共聚焦显微镜特征。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-26 DOI: 10.1111/vop.70033
Remington X Chan, Eric C Ledbetter
{"title":"In Vivo Confocal Microscopy Features of Corneal Dystrophy in Siberian Huskies.","authors":"Remington X Chan, Eric C Ledbetter","doi":"10.1111/vop.70033","DOIUrl":"https://doi.org/10.1111/vop.70033","url":null,"abstract":"<p><strong>Objective: </strong>To describe the morphological features of corneal dystrophy in Siberian Huskies using in vivo confocal microscopy (IVCM).</p><p><strong>Animals studied: </strong>Twenty-one dogs.</p><p><strong>Procedures: </strong>A prospective case-control study was performed. Siberian Huskies with (n = 13 dogs) and without (n = 8) corneal dystrophy were evaluated. Complete ophthalmic and IVCM examinations (Heidelberg Retina Tomograph and Rostock Cornea Module) were performed for each case.</p><p><strong>Results: </strong>All dogs with corneal dystrophy demonstrated characteristic bilateral, round-to-oval, refractile, crystalline corneal opacities visible within the stroma by slit-lamp biomicroscopy. The median age of dogs with corneal dystrophy was 5.0 years (range: 2-13 years), with eight females and five males included. During IVCM, dense accumulations of fine, needle-like, tapered, hyperreflective structures were present within the axial corneal stroma of each dog. The length of the spindles varied from several μm to > 400 μm and the structures were commonly present in dense clumps. Amorphous, thicker, crystalline deposits with blunted ends were present less frequently and intermixed with the needle-like structures. Other corneal anatomic features were generally obscured by the deposits, but the surrounding regions appeared morphologically normal, including the epithelium, keratocytes, corneal nerves, and endothelium. Siberian Huskies without corneal dystrophy were presented for various other ophthalmic conditions, including cataracts and primary glaucoma. The median age of control dogs was 1.5 years (range: 1-9 years), with five females and three males included. Similar hyperreflective deposits were not detected by IVCM in any dogs from the control group.</p><p><strong>Conclusions: </strong>Application of IVCM can aid in the characterization of corneal dystrophies in Siberian Huskies.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Correction of Prolapse of Nictitating Membrane Gland Using a Variant of the Pocket Technique: A Retrospective Study on 101 Dogs and 126 Eyes. 应用一种不同的口袋技术矫正舌膜腺脱垂:对101只狗和126只眼的回顾性研究。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-26 DOI: 10.1111/vop.70031
Arnaud Guionnet, Firmin Weverberg
{"title":"Surgical Correction of Prolapse of Nictitating Membrane Gland Using a Variant of the Pocket Technique: A Retrospective Study on 101 Dogs and 126 Eyes.","authors":"Arnaud Guionnet, Firmin Weverberg","doi":"10.1111/vop.70031","DOIUrl":"https://doi.org/10.1111/vop.70031","url":null,"abstract":"<p><strong>Objective: </strong>To retrospectively investigate the outcome of a modified Morgan pocket technique that included temporary ventral scleral gland fixation to treat prolapse of the nictitans gland.</p><p><strong>Animal studied: </strong>The files of 101 client-owned dogs (126 eyes) between 2015 and 2024 were retrospectively analyzed.</p><p><strong>Results: </strong>All the surgeries were completed in under 10 min. Follow-up was between 180 to 3285 days (mean 1190 days) in 119/126 (94%) eyes and three years in 81/126 (64.3%) eyes. The technique achieved successful surgical repositioning in 125/126 (99.2%) eyes after one surgery, with only one eye (1/126 (0.8%)) having a recurring prolapse that was successfully managed by repeating the technique. Seven other immediate postoperative complications (7/126, 5.6% of the eyes) were recorded, including lacrimal cysts in 5/126 (4%) eyes and corneal ulceration in 2/126 (1.6%) eyes. All cysts were treated with local drainage, two under general anesthesia and three under sedation and topical anesthesia. Additional complications occurred in 14/101 (13.9%) of the animals, including keratoconjunctivitis sicca and ulcerative keratoconjunctivitis of different degrees of severity. Given the long follow-up and low number of cases affected, it was not known if these problems might have been associated with some aspects of the surgical treatment.</p><p><strong>Conclusions: </strong>The technique described included a temporary fixation of the gland before closure of the pocket with successful long-term repositioning of the gland in 99.2% of eyes after the first attempt. Cysts and recurrence were infrequent complications. Further studies could investigate if the technique might be adapted to minimize complications.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiences and Occupational Self-Efficacy of Neurominorities in Specialty Veterinary Medicine: Challenges, Solutions, and Recommendations for Progress. 专业兽医中神经少数群体的经验和职业自我效能:挑战、解决方案和进步建议。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-19 DOI: 10.1111/vop.70030
Emily K Tucker-Retter, Hans D Westermeyer
{"title":"Experiences and Occupational Self-Efficacy of Neurominorities in Specialty Veterinary Medicine: Challenges, Solutions, and Recommendations for Progress.","authors":"Emily K Tucker-Retter, Hans D Westermeyer","doi":"10.1111/vop.70030","DOIUrl":"https://doi.org/10.1111/vop.70030","url":null,"abstract":"<p><strong>Objective: </strong>To assess the challenges faced by specialists and current residents with neurodevelopmental differences (neurominorities) throughout their careers, including the solutions and accommodations that have worked for them.</p><p><strong>Subjects studied: </strong>162 specialty veterinarians, 53 current residents.</p><p><strong>Procedures: </strong>An online survey was distributed to neurominority specialists and residents through gatekeeper organizations (specialty colleges). The survey asked respondents to identify challenges they experienced during their veterinary training career and rank how much of an impact their neurominority status had on those challenges. Chi-square tests compared the distribution of challenges between respondents with specific neurotypes. Open-ended questions gathered qualitative information on solutions and accommodations.</p><p><strong>Results: </strong>The most responses came from Emergency and Critical Care (19.07%) and Laboratory Animal Medicine (18.14%). Attention deficit and hyperactivity disorder (ADHD) was the most common neurotype (73.02%). ADHD was consistently associated with challenges around executive functioning, while autism spectrum conditions (ASC) were more likely to describe challenges with social interactions and masking. Respondents with ADHD were more likely to report an increase in the impact of their neurotype over time. Respondents described that not knowing about their diagnoses earlier presented challenges. Solutions included therapy, medication, self-acceptance, and personalized accommodations. Neurominorities highlighted positive strengths such as empathy, creativity, and attention to detail. Veterinarians in this survey expressed a need for more awareness and acceptance of neurodiversity within the profession.</p><p><strong>Conclusions: </strong>The results of this survey support the need for increased awareness and acceptance of neurominorities in veterinary medicine and an understanding of the unique challenges they face during their careers.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serial Evaluation of Pectinate Ligament Morphology Is Not Useful in Predicting the Onset of Intraocular Pressure Elevation in Dogs With Primary Angle Closure Glaucoma. 果胶韧带形态的系列评估在预测原发性闭角型青光眼犬眼压升高的发病中并不有用。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-19 DOI: 10.1111/vop.70029
Hans D Westermeyer, Jacklyn H Salmon, Björn Ekesten, Michael G Davidson, Christine Heinrich, Ashley E Zibura, Paul E Miller
{"title":"Serial Evaluation of Pectinate Ligament Morphology Is Not Useful in Predicting the Onset of Intraocular Pressure Elevation in Dogs With Primary Angle Closure Glaucoma.","authors":"Hans D Westermeyer, Jacklyn H Salmon, Björn Ekesten, Michael G Davidson, Christine Heinrich, Ashley E Zibura, Paul E Miller","doi":"10.1111/vop.70029","DOIUrl":"https://doi.org/10.1111/vop.70029","url":null,"abstract":"<p><strong>Objective: </strong>To determine whether serial evaluation of pectinate ligament morphology could aid in predicting the onset of elevated intraocular pressure (IOP) in eyes predisposed to primary angle closure glaucoma (PACG).</p><p><strong>Animals studied: </strong>The second eye of dogs affected with PACG (20) that had already developed elevated IOP in the first eye and normal dogs (12) with no history of glaucoma.</p><p><strong>Procedures: </strong>Serial goniophotographs of all quadrants of the iridocorneal angle were obtained every 9 months over approximately 18 months in normal dogs. Images were obtained every 3 months in dogs with PACG until that eye developed elevated IOP. A modified ZibWest score was calculated for each image. The earliest ZibWest score was then compared with the last ZibWest score for each eye. Additionally, matched images from the same quadrant from the first and last time point were presented to masked experienced evaluators to see whether the progression of abnormalities could be detected.</p><p><strong>Results: </strong>A difference in ZibWest scores between the first and the last time point for each eye was not detected across all dogs (p = 0.3673), within dogs affected with PACG (p = 0.2665), or normal dogs (p = 0.3953). Experienced evaluators were unable to detect significant progression of pectinate ligament abnormalities.</p><p><strong>Conclusions: </strong>Serial gonioscopic evaluation of pectinate ligament morphology does not appear to be useful in the prediction of the time of onset of elevated IOP in dogs with PACG.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasonographic Appearance of a Posterior Lenticonus in a Cat. 猫后晶状体的超声表现。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-16 DOI: 10.1111/vop.70024
Antonella Rampazzo, Marc Orts-Porcar, Francesca Del Chicca
{"title":"Ultrasonographic Appearance of a Posterior Lenticonus in a Cat.","authors":"Antonella Rampazzo, Marc Orts-Porcar, Francesca Del Chicca","doi":"10.1111/vop.70024","DOIUrl":"https://doi.org/10.1111/vop.70024","url":null,"abstract":"<p><p>The objective of this study is to present high-quality and up-to-date ocular ultrasonographic images and videos of a posterior lenticonus with concomitant mature cataract in a cat. Additionally, the clinical findings, surgical treatment, and outcome are reported for completeness and to confirm the diagnosis. An 8-year-old castrated male domestic shorthair cat presented due to unilateral cataract. Ophthalmological examination revealed a mature cataract without clinically detectable uveitis. Hematological and biochemical analyses were unremarkable, and tests for common infectious diseases associated with feline uveitis were negative. Electroretinography and ocular ultrasound were performed as part of the presurgical planning for phacoemulsification. Retinal function was normal. Ultrasonographic examination revealed a severely distorted shape of the posterior lens capsule (PLC) with hyperechoic material protruding into the vitreous body. Neither a PLC fibrovascular plaque nor a persistent hyaloid artery was identified. These findings were interpreted as a possible rupture of the posterior lens capsule with lens material extruding into the vitreous body. Posterior lenticonus was considered a less likely differential diagnosis. The owner elected to proceed with phacoemulsification surgery. Intraoperatively, the posterior lens capsule was found to be intact. An axial posterior lenticonus with cataractous lens material bulging together with the capsule into vitreous was identified. An intraocular lens was successfully implanted. Given the better surgical prognosis compared to capsule ruptures, posterior lenticonus, although rare, should be considered a differential diagnosis, particularly when a cone-shaped protrusion lacking Doppler signal is identified at the posterior lens capsule extending into the vitreous body.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Inclusive Language in Veterinary Medicine: A Step Toward a More Equitable Workplace. 在兽医中使用包容性语言:迈向更公平的工作场所的一步。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-12 DOI: 10.1111/vop.70025
Adesola Odunayo, Zenithson Ng
{"title":"Navigating Inclusive Language in Veterinary Medicine: A Step Toward a More Equitable Workplace.","authors":"Adesola Odunayo, Zenithson Ng","doi":"10.1111/vop.70025","DOIUrl":"https://doi.org/10.1111/vop.70025","url":null,"abstract":"<p><p>Stigmatizing language, often rooted in unconscious bias, can reinforce power imbalances, perpetuate stereotypes, and compromise inclusivity. Inclusive language-defined as communication that respects diversity, acknowledges lived experiences and promotes equality-fosters a supportive and welcoming environment for all team members and clients. Its application extends to verbal interactions, written communication, policies, and educational materials. Strategies to implement inclusive language include adopting people-first phrasing, avoiding ableist expressions, respecting gender diversity, and embracing cultural humility. Organizations can further support inclusivity through training programs and leadership modeling. By prioritizing inclusive language, veterinary teams not only strengthen collaboration and equity but also enhance team dynamics, client satisfaction, and patient care. Recognizing the power of words and choosing them thoughtfully promotes a culture of belonging and respect, benefiting individuals and the organization as a whole.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Vitro Efficacy Testing of TONS504-Based Photodynamic Antimicrobial Chemotherapy (TONS504-PACT) Under a 405-nm Light-Emitting Diode Against Antimicrobial-Resistant Bacteria Causing Canine Keratitis. 基于tons504的405nm发光二极管光动力抗菌化疗(TONS504-PACT)对犬角膜炎耐药菌的体外疗效测试
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-09 DOI: 10.1111/vop.70028
Tomoya Furujo, Kazuki Harada, Norihiko Ito, Isao Sakata, Tomohiro Osaki
{"title":"In Vitro Efficacy Testing of TONS504-Based Photodynamic Antimicrobial Chemotherapy (TONS504-PACT) Under a 405-nm Light-Emitting Diode Against Antimicrobial-Resistant Bacteria Causing Canine Keratitis.","authors":"Tomoya Furujo, Kazuki Harada, Norihiko Ito, Isao Sakata, Tomohiro Osaki","doi":"10.1111/vop.70028","DOIUrl":"https://doi.org/10.1111/vop.70028","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the in vitro efficacy of photodynamic antimicrobial chemotherapy (PACT) using TONS504, a newly developed hydrophilic and cationic photosensitizer, under a blue light emitting diode (LED) against antimicrobial-resistant bacteria isolated from dogs with keratitis.</p><p><strong>Methods: </strong>Three bacterial strains (i.e., methicillin-resistant Staphylococcus pseudintermedius, extended-spectrum beta-lactamase-producing Escherichia coli, and Pseudomonas aeruginosa), isolated from two dogs with keratitis, were used in this study after antimicrobial susceptibility tests. PACT using TONS504 (0.1-100 mg/L) was performed under a 405-nm LED at 30 J/cm<sup>2</sup> (20 mW/cm<sup>2</sup>, 25 min) against bacterial suspensions (1.0 × 10<sup>7-8</sup> CFU). Bacterial strains that were unexposed, exposed to TONS504 only, or exposed to blue light only served as controls. Antimicrobial effects were assessed by calculating the survival fraction based on the assessment of colony-forming units (CFU) on agar plates.</p><p><strong>Results: </strong>Exposure to TONS504 or blue light only did not decrease the bacterial survival fraction against any of the strains. After TONS504-PACT under blue light against S. pseudintermedius, no colonies were observed at any TONS504 concentration, resulting in an approximate reduction of 2.3 × 10<sup>8</sup> in the survival fraction. TONS504-PACT under blue light against E. coli and P. aeruginosa at 10 mg/L of TONS504 showed the greatest reduction in survival fraction, and the reduction was substantially lower than those of the respective controls.</p><p><strong>Conclusions: </strong>TONS504-PACT under blue light exhibited satisfactory activity against antimicrobial-resistant bacteria in vitro. Further research on the safety and clinical efficacy of TONS504-PACT under blue light is required; however, it is a potential treatment for antimicrobial-resistant bacterial keratitis in veterinary ophthalmology.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tarsal Gold Weight Implant as a Surgical Treatment for Eyelid Akinesia Related to Facial Paralysis. 睑金重磅植入术治疗面瘫相关眼睑肌无力。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-05 DOI: 10.1111/vop.70026
Marta Viñas, Manuela Crasta, Daniele Corlazzoli, Nunzio D'Anna
{"title":"Tarsal Gold Weight Implant as a Surgical Treatment for Eyelid Akinesia Related to Facial Paralysis.","authors":"Marta Viñas, Manuela Crasta, Daniele Corlazzoli, Nunzio D'Anna","doi":"10.1111/vop.70026","DOIUrl":"https://doi.org/10.1111/vop.70026","url":null,"abstract":"<p><strong>Objective: </strong>To describe the use and outcome of a tarsal gold weight implant as a surgical treatment for facial paralysis in two patients.</p><p><strong>Animals studied: </strong>Case 1: a four-year-old female neutered French Bulldog was referred for a perforated corneal ulcer of the right eye and a history of ipsilateral recurrent otitis. Case 2: a seven-year-old male neutered domestic short hair was referred for a deep corneal ulcer of the left eye and a four-year history of facial paralysis.</p><p><strong>Procedures: </strong>Complete ophthalmic examination revealed facial paralysis in both patients; associated with a perforated corneal ulcer in case 1 and with a descemetocele in case 2. Surgical treatment was required in both patients for corneal repair. Tarsal gold weight implantation was performed in both patients. An eyelid gold weight was implanted and anchored to the tarsal plate with 5-0 Nylon suture; the subcutaneous and skin layers were sutured with 5-0 Polyglactin910 in a simple interrupted pattern. Eyelid motion was achieved after surgery. Post-operative re-examination at 3 years for case 1 and 18 months for case 2 revealed persistence of facial nerve paralysis in both patients. Passive closure and active opening of the affected eyelid were noted in both patients. No signs of active exposure keratitis were noted.</p><p><strong>Conclusion: </strong>These two cases represent a novel surgical treatment to support passive blink for facial paralysis in a dog and cat using a human tarsal gold eyelid weight.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infracyanine Green-Based Photodynamic Therapy for Immune-Mediated Keratitis in Horses. 马免疫介导性角膜炎的紫花青绿光动力治疗。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-05 DOI: 10.1111/vop.70027
Kimberly P Lam, Deborah A Keys, Richard J McMullen
{"title":"Infracyanine Green-Based Photodynamic Therapy for Immune-Mediated Keratitis in Horses.","authors":"Kimberly P Lam, Deborah A Keys, Richard J McMullen","doi":"10.1111/vop.70027","DOIUrl":"https://doi.org/10.1111/vop.70027","url":null,"abstract":"<p><strong>Objective: </strong>To describe infracyanine green-based photodynamic therapy (InfraCG-PDT) and evaluate outcomes in horses with immune-mediated keratitis (IMMK).</p><p><strong>Animals studied: </strong>Medical records from 2014 to 2020 from the Equine Clinic Munich-Riem, Germany, and Auburn University Equine Ophthalmology Service identified horses diagnosed with IMMK following ophthalmic examination that had undergone InfraCG-PDT.</p><p><strong>Procedures: </strong>Multiple intrastromal injections of EmunDo (InfraCG, A.R.C. Laser, Nuernberg, Germany) within an affected quadrant or the entire cornea were treated with diffuse diode laser energy (FOX A.R.C., Laser, Nuernberg, Germany, 500 mW at 30s cycles) irradiation between 75 J (J, quadrant) and 300 J (entire cornea).</p><p><strong>Results: </strong>Fifty-one eyes (22 OS, 19 OD, 10 OU) from 47 horses were included (22 geldings, 20 mares, and 5 stallions) from 15 breeds aged between 4 and 29 years (median 14 years). Individual quadrants (28/51 eyes, 54.9%) or the entire cornea (23/51 eyes, 45.1%) were treated. Complications were defined as immediate: intrastromal fracture (4/51 eyes, 7.8%), intracameral InfraCG (7/51 eyes, 13.7%), and an epithelial blister (1/51 eyes, 1.9%) or short term: prolonged dye retention (51/51 eyes, 100%, with gradual reduction over a 12-week period) and superficial corneal ulceration (15/51 eyes, 29.4%). Globe threatening ulcers (3/51 eyes, 5.9%) resolved without significant complications. IMMK remained inactive (controlled or managed with improvement in ocular lesions) in 31/40 horses (77.5%) during follow-up (mean 223.0 ± 269.3 days; range 14-1095 days), 4/40 horses (10.0%) required additional treatment, and 5/40 horses (12.5%) were lost to follow-up.</p><p><strong>Conclusions: </strong>InfraCG-PDT may be an effective treatment for horses with IMMK. Further studies are needed to optimize this treatment modality.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Repair of Deep Melting Ulcers With Freeze-Dried Amniotic Membrane Transplantation in Dogs and Cats. 冻干羊膜移植修复犬、猫深融性溃疡。
IF 1.7 4区 农林科学
Veterinary ophthalmology Pub Date : 2025-05-05 DOI: 10.1111/vop.70023
Cloé Lengellé
{"title":"Surgical Repair of Deep Melting Ulcers With Freeze-Dried Amniotic Membrane Transplantation in Dogs and Cats.","authors":"Cloé Lengellé","doi":"10.1111/vop.70023","DOIUrl":"https://doi.org/10.1111/vop.70023","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the efficacy of freeze-dried amniotic membrane (FDAM) used in veterinary medicine (Vetrix EyeQ) for the surgical treatment of deep melting ulcers in dogs and cats.</p><p><strong>Materials and methods: </strong>A total of 15 dogs and 5 cats treated for deep melting corneal ulcers were included in this retrospective study. Following keratectomy, a simple or multilayer FDAM was placed into the keratectomy bed and sutured with 9/0 polyglactin suture material. A temporary third eyelid flap was performed for each case. Follow-up examinations were performed on average 18, 45, and 90 days after surgery. Final evaluation included assessment of corneal healing, preserved vision, and residual corneal opacities.</p><p><strong>Results: </strong>A total of 20 eyes were treated between 2019 and 2023. Nine dog and four cat breeds were represented. Mean healing time was 17 ± 2 days. At 18 days postsurgery, inflammatory reaction with superficial vascularization was present in all eyes (20/20). At 45 days, 45% (9/20) of eyes showed persistent corneal neovascularization, mild corneal fibrosis, and focal corneal pigmentation. At 90 days, persistent severe pigmentation was observed in 10% (2/20) of eyes. Corneal transparency was successfully restored, and vision was preserved in 90% of cases (18/20).</p><p><strong>Conclusion: </strong>FDAM transplantation was effective in treating melting corneal ulcers in dogs and cats.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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