Ultrasound Biomicroscopic Study of the Effects of 1% Tropicamide on the Anterior Segment and Ciliary Body in Cats.

IF 1.3 4区农林科学 Q2 VETERINARY SCIENCES

Veterinary ophthalmology Pub Date : 2025-10-06 DOI:10.1111/vop.70083

Donghee Kim, Yunji Her, Ji Seung Jung, Jiyi Hwang, Sooyeon Lee, Mirae Lee, Haemi Seol, Soohyun Kim, Kyung-Mee Park

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引用次数: 0

Abstract

Objective: To investigate the effects of 1% tropicamide on intraocular pressure (IOP), anterior chamber morphology, and ciliary body dynamics in cats using ultrasound biomicroscopy (UBM).

Methods: A total of 28 eyes from 14 clinically healthy cats were evaluated before and 30 min after unilateral instillation of 1% tropicamide in the right eye (OD), with the left eye (OS) serving as a control. Parameters assessed included pupil size, IOP, and UBM-derived measurements of the iridocorneal angle (ICA), angle opening distance (AOD), ciliary cleft width (CCW), length (CCL), area (CCA), ciliary body axial length (CBAXL), and ciliary process-scleral angle (CPSA).

Results: Tropicamide significantly increased IOP in the treated eye (OD) but not in the control eye (OS). UBM analysis revealed significant reductions in ICA and CCW in OD, while other anterior chamber and ciliary body parameters showed no meaningful changes. In contrast, no significant alterations were observed in any anterior chamber or ciliary body parameters in OS.

Conclusion: These findings suggest that tropicamide-induced IOP elevation in cats results from anterior chamber angle narrowing, emphasizing the need for caution when using mydriatics in patients at risk for ocular hypertension.

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1%托品酰胺对猫前段和纤毛体影响的超声生物显微镜研究。

目的：应用超声生物显微镜（UBM）观察1%托品酰胺对猫眼压、前房形态和睫状体动力学的影响。方法：选取14只临床健康猫28只眼，在右眼（OD）单侧注射1% tropicamide前和30 min后进行评价，左眼（OS）作为对照。评估的参数包括瞳孔大小、IOP和基于umm的虹膜-角膜角（ICA）、角开口距离（AOD）、睫状裂隙宽度（CCW）、长度（CCL）、面积（CCA）、睫状体轴长（CBAXL）和睫状突-巩膜角（CPSA）。结果：托品胺可显著提高治疗眼（OD）的IOP，而对对照眼（OS）无显著影响。UBM分析显示，OD的ICA和CCW明显降低，而其他前房和纤毛体参数无明显变化。相比之下，在OS中没有观察到任何前房或纤毛体参数的明显改变。结论：这些研究结果表明，热带酰胺引起的猫IOP升高是由于前房角变窄，强调在有高眼压风险的患者中使用mydritic时需要谨慎。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary ophthalmology 农林科学-兽医学

CiteScore

2.70

自引率

37.50%

发文量

审稿时长

12-24 weeks

期刊介绍： Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.