World Journal of Gastrointestinal Surgery最新文献

筛选
英文 中文
Feasibility of single-port laparoscopic appendectomy for retrocecal appendicitis: A propensity score-matched study with multi-port laparoscopic appendectomy. 单孔腹腔镜阑尾切除术治疗盲肠后阑尾炎的可行性:一项与多孔腹腔镜阑尾切除术倾向评分匹配的研究。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.105925
Sang-Ah Woo, Seung Jae Roh, Nak Song Sung, Won Jun Choi
{"title":"Feasibility of single-port laparoscopic appendectomy for retrocecal appendicitis: A propensity score-matched study with multi-port laparoscopic appendectomy.","authors":"Sang-Ah Woo, Seung Jae Roh, Nak Song Sung, Won Jun Choi","doi":"10.4240/wjgs.v17.i7.105925","DOIUrl":"10.4240/wjgs.v17.i7.105925","url":null,"abstract":"<p><strong>Background: </strong>Retrocecal appendicitis, the most common anatomical type, presents diagnostic and surgical challenges. Single-port laparoscopic appendectomy (SPLA) has been proposed as an alternative to multi-port laparoscopic appendectomy (MPLA) with advancements in minimally invasive surgery. However, few studies have compared the perioperative outcomes between the SPLA and MPLA for retrocecal appendicitis.</p><p><strong>Aim: </strong>To compare the efficacy and safety between the SPLA and MPLA in treating retrocecal appendicitis, focusing on perioperative outcomes.</p><p><strong>Methods: </strong>This retrospective study analyzed data from 1041 patients who underwent SPLA or MPLA at Konyang University Hospital between October 2011 and February 2023. Propensity score matching (PSM) was used to minimize selection bias, resulting in 235 patients in each group. Additionally, non-inferiority tests, <i>post-hoc</i> analysis, and multivariable regression analysis were performed to validate the results and assess factors affecting postoperative outcomes.</p><p><strong>Results: </strong>After PSM, SPLA showed shorter operation time (43.8 ± 15.8 minutes <i>vs</i> 51.6 ± 18.7 minutes; <i>P</i> < 0.001) and lower estimated blood loss (EBL, 6.5 ± 7.8 mL <i>vs</i> 8.6 ± 8.3 mL; <i>P</i> < 0.001) than MPLA. No significant differences were observed in complications, pain scores, or length of hospital stay. SPLA was not inferior to MPLA in the main outcomes, except for the complication rate, where statistical power was insufficient. Multivariable regression confirmed SPLA as an independent factor for operation time and EBL.</p><p><strong>Conclusion: </strong>SPLA is more feasible than MPLA for retrocecal appendicitis, offering advantages in operation time and estimated blood loss. This study supports SPLA as a viable alternative that enhances postoperative recovery.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"105925"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ice-breaking sign: A radiological sign influencing the treatment strategies for choledocholithiasis. 破冰征象:影响胆总管结石治疗策略的影像学征象。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.106712
Xiao-Yu Zhao, Ming Chen, Gang Wang, Long Cui, Zhi Xu, Chun-Sheng Hou, Li-Xin Wang, Ling-Fu Zhang, Xiao-Feng Ling
{"title":"Ice-breaking sign: A radiological sign influencing the treatment strategies for choledocholithiasis.","authors":"Xiao-Yu Zhao, Ming Chen, Gang Wang, Long Cui, Zhi Xu, Chun-Sheng Hou, Li-Xin Wang, Ling-Fu Zhang, Xiao-Feng Ling","doi":"10.4240/wjgs.v17.i7.106712","DOIUrl":"10.4240/wjgs.v17.i7.106712","url":null,"abstract":"<p><strong>Background: </strong>Choledocholithiasis is a common benign disease of the biliary tract. We identified a particular type of choledocholithiasis characterized by sudden narrowing of the common bile duct at the site of impaction, which caused a marked increase in surgical difficulty and risk compared to treatment for typical choledocholithiasis. This phenomenon has not been described in previous studies.</p><p><strong>Aim: </strong>To propose the ice-breaking sign and evaluate its influence on treatment strategies for choledocholithiasis.</p><p><strong>Methods: </strong>Using a retrospective case-control study design, patients who were diagnosed with common bile duct stones and admitted to the Emergency Department of Peking University Third Hospital between January 2018 and December 2023 were included. Propensity score matching was used to match cases and controls. Univariate analysis was conducted to assess the differences in clinical data between the two groups of patients.</p><p><strong>Results: </strong>There were no significant differences in the baseline data between the two groups, except for higher incidence of jaundice, alkaline phosphatase and total bilirubin in the ice-breaking sign group. Compared to the control group, the ice-breaking sign group had lower success rates for endoscopic retrograde cholangiopancreatography (25.0% <i>vs</i> 81.8%, <i>P</i> = 0.006) and laparoscopic common bile duct exploration (69.4% <i>vs</i> 93.8%, <i>P</i> = 0.007), longer operation time (148.04 ± 60.55 minutes <i>vs</i> 106.15 ± 35.21 minutes, <i>P</i> = 0.001), higher likelihood of T-tube placement (62.2% <i>vs</i> 31.3%, <i>P</i> = 0.016) and using lithotripsy techniques during surgery (29.7% <i>vs</i> 0%, <i>P</i> = 0.001), more intraoperative bleeding [25.0 (20.0-50.0) mL <i>vs</i> 10.0 (10.0-20.0) mL, <i>P</i> < 0.001] and longer postoperative hospital stay [6.50 (5.0-9.0) days <i>vs</i> 5.50 (3.0-6.50) days, <i>P</i> = 0.002]. The ice-breaking sign group showed significantly more dilatation in the proximal than distal bile duct.</p><p><strong>Conclusion: </strong>The ice-breaking sign, a newly identified radiological phenomenon, may influence therapeutic decisions in choledocholithiasis, suggesting laparoscopic common bile duct exploration as the preferred approach over endoscopic retrograde cholangiopancreatography in patients exhibiting this sign.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"106712"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative computed tomography-based risk stratification model validation for postoperative pancreatic ductal adenocarcinoma recurrence. 术前基于计算机断层扫描的胰腺导管腺癌术后复发风险分层模型验证。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.107804
Xiao-Hui Liu, Jing-Hong Xie, Xi-Song Zhu, Li-Heng Liu
{"title":"Preoperative computed tomography-based risk stratification model validation for postoperative pancreatic ductal adenocarcinoma recurrence.","authors":"Xiao-Hui Liu, Jing-Hong Xie, Xi-Song Zhu, Li-Heng Liu","doi":"10.4240/wjgs.v17.i7.107804","DOIUrl":"10.4240/wjgs.v17.i7.107804","url":null,"abstract":"<p><strong>Background: </strong>The computed tomography (CT)-based preoperative risk score was developed to predict recurrence after upfront surgery in patients with resectable pancreatic ductal adenocarcinoma (PDAC) in South Korea. However, whether it performs well in other countries remains unknown.</p><p><strong>Aim: </strong>To externally validate the CT-based preoperative risk score for PDAC in a country outside South Korea.</p><p><strong>Methods: </strong>Consecutive patients with PDAC who underwent upfront surgery from January 2016 to December 2019 at our institute in a country outside South Korea were retrospectively included. The study utilized the CT-based risk scoring system, which incorporates tumor size, portal venous phase density, tumor necrosis, peripancreatic infiltration, and suspicious metastatic lymph nodes. Patients were categorized into prognosis groups based on their risk score, as good (risk score < 2), moderate (risk score 2-4), and poor (risk score ≥ 5).</p><p><strong>Results: </strong>A total of 283 patients were evaluated, comprising 170 males and 113 females, with an average age of 63.52 ± 8.71 years. Follow-up was conducted until May 2023, and 76% of patients experienced tumor recurrence with median recurrence-free survival (RFS) of 29.1 ± 1.9 months. According to the evaluation results of Reader 1, the recurrence rates were 39.0% in the good prognosis group, 82.1% in the moderate group, and 84.5% in the poor group. In comparison, Reader 2 reported recurrence rates of 50.0%, 79.5%, and 88.9%, respectively, across the same prognostic categories. The study validated the effectiveness of the risk scoring system, demonstrating better RFS in the good prognosis group.</p><p><strong>Conclusion: </strong>This research validated that the CT-based preoperative risk scoring system can effectively predict RFS in patients with PDAC, suggesting that it may be valuable in diverse populations.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"107804"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revolutionizing hepatolithiasis management: Transformative role of DynaCT in imaging and intervention. 革命性的肝内胆管管理:DynaCT在影像学和干预中的变革作用。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.103492
Thai-Hau Koo, Xue-Bin Leong, Yi-Lin Lee, Firdaus Hayati, Mohd Hazeman Zakaria, Andee Dzulkarnaen Zakaria
{"title":"Revolutionizing hepatolithiasis management: Transformative role of DynaCT in imaging and intervention.","authors":"Thai-Hau Koo, Xue-Bin Leong, Yi-Lin Lee, Firdaus Hayati, Mohd Hazeman Zakaria, Andee Dzulkarnaen Zakaria","doi":"10.4240/wjgs.v17.i7.103492","DOIUrl":"10.4240/wjgs.v17.i7.103492","url":null,"abstract":"<p><p>In this editorial, we comment on the article by Ye <i>et al</i>. We specifically focused on the novel use of DynaCT biliary soft tissue reconstruction technology in the diagnosis and treatment of hepatolithiasis with bile duct stenosis, which is an innovative approach for enhancing the preoperative evaluation and surgical outcomes in hepatolithiasis. This study also highlights the limitations of conventional imaging techniques such as computed tomography and magnetic resonance cholangiopancreatography, which have low sensitivity for small stones and complex biliary strictures. Given the intricate anatomy of the biliary system and the challenges posed by limited visualization using conventional methods, DynaCT addresses these issues by providing high-resolution, three-dimensional reconstruction of the bile ducts, stones, and vascular structures, thus improving anatomical clarity and enabling precise surgical planning. We also focused specifically on the limitations of DynaCT, such as the need for specialized equipment and patient selection criteria, as well as its advantages and disadvantages compared with conventional PTOBF approaches. Overall, DynaCT represents a significant advancement in hepatolithiasis management, with the potential to become a standard imaging modality for safer and more effective biliary procedures.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"103492"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful conservative management of emphysematous gastritis in an elderly patient with multiple comorbidities: A case report. 高龄合并多重合并症患者肺气性胃炎的成功保守治疗:1例报告。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.107046
Nawaf Alshahwan, Abdullah A Alqarzaie, Saleh Husam Aldeligan, Abdulaziz Abdulmuhsin Alqusiyer, Abdulaziz Alnumay, Hassan Mashbari, Abdulaziz Alkanhal
{"title":"Successful conservative management of emphysematous gastritis in an elderly patient with multiple comorbidities: A case report.","authors":"Nawaf Alshahwan, Abdullah A Alqarzaie, Saleh Husam Aldeligan, Abdulaziz Abdulmuhsin Alqusiyer, Abdulaziz Alnumay, Hassan Mashbari, Abdulaziz Alkanhal","doi":"10.4240/wjgs.v17.i7.107046","DOIUrl":"10.4240/wjgs.v17.i7.107046","url":null,"abstract":"<p><strong>Background: </strong>Emphysematous gastritis (EG) is a rare and serious condition that has fatal consequences. Although its clinical presentation is not specific, radiological imaging is characterized by intramural gastric gas. Defects in the stomach mucosal barrier and invasion of gas-producing organisms are believed to be the cause.</p><p><strong>Case summary: </strong>An 88-year-old male with multiple comorbidities presented to our center with abdominal pain and increased stoma output as chief complaints. Upon further investigation he was found to have EG. Despite the high mortality risk without intervention, the patient and family declined operative intervention.</p><p><strong>Conclusion: </strong>This case report underscored the challenges of managing a critically ill elderly patient with a history of multiple comorbidities and extensive abdominal surgeries and highlighted the successful use of conservative measures in treating EG.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"107046"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia. 双能ct对急性闭塞性肠系膜缺血不可逆肠壁坏死的诊断价值。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.105956
Ju-Shun Yang, Zhen-Yu Xu, Fei-Xiang Chen, Mei-Rong Wang, Xiao-Le Fan, Bo-Sheng He
{"title":"Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia.","authors":"Ju-Shun Yang, Zhen-Yu Xu, Fei-Xiang Chen, Mei-Rong Wang, Xiao-Le Fan, Bo-Sheng He","doi":"10.4240/wjgs.v17.i7.105956","DOIUrl":"10.4240/wjgs.v17.i7.105956","url":null,"abstract":"<p><strong>Background: </strong>Irreversible transmural intestinal necrosis (ITIN) is associated with high mortality rates in patients with acute occlusive mesenteric ischemia (AOMI). Currently, there are not many studies on the use of dual energy computed tomography (DECT) for evaluating ITIN.</p><p><strong>Aim: </strong>To evaluate the diagnostic value of DECT for ITIN in AOMI.</p><p><strong>Methods: </strong>The cases and computed tomography (CT) images of 102 patients with clinically diagnosed AOMI (including 48 ITIN) from January 2012 to January 2022 were retrospectively collected. The CT scans included both multidetector CT and DECT. The raw data from DECT portal-venous phase were reconstructed into 120 kVp mixed energy image, 50 keV virtual monoenergetic imaging, and iodine map. Two radiologists independently completed the subjective visual assessment of CT signs related to AOMI. Objective parameters, including the attenuation of the normal and lesion intestinal wall segment (CT<sub>50 keV lesion</sub>, CT<sub>50 keV normal/lesion</sub>) and iodine concentrations (IC<sub>lesion</sub> and IC<sub>normal/lesion</sub>), were quantified. Furthermore, multivariate logistic regression, receiver operating characteristic curves, and area under the curve (AUC) values were used to evaluate the subjective and objective indicators in predicting ITIN.</p><p><strong>Results: </strong>Regarding subjective signs, logistic regression analysis revealed reduced or absent bowel wall enhancement [odds ratio (OR) = 5.576, 95% confidence interval (CI): 1.547-20.093], bowel dilation (OR = 11.613, 95%CI: 3.790-35.586), and parenchymatous organ infarction (OR = 4.727, 95%CI: 1.536-14.551) were independent risk factors for the ITIN. CT subjective signs had a high diagnostic efficacy for ITIN (AUC = 0.853). The two DECT objective parameters also exhibited excellent diagnostic value for ITIN, with an AUC of 0.79, a cut-off value of CT<sub>50 keV normal/lesion</sub> = 2.81, and an AUC of 0.777 with a cut-off value of IC<sub>normal/lesion</sub> = 2.39. The Delong test showed that there was no significant difference in the efficacy of subjective CT signs and objective DECT parameters (<i>P</i> > 0.05). Importantly, we observed that IC<sub>normal/lesion</sub> combined with subjective signs (bowel dilation and parenchymatous organ infarction) had the highest predictive performance (AUC = 0.894), sensitivity (100%), and specificity (70.83%), which was statistically different from the AUC of CT subjective signs (<i>P</i> = 0.017).</p><p><strong>Conclusion: </strong>IC<sub>normal/lesion</sub> (DECT-based features) combined with CT subjective signs (bowel dilatation and parenchymatous organ infarction) showed favorable predictive performance for ITIN in AOMI, which may help clinicians develop timely treatment strategies.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"105956"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acellular mucin in neoplastic and non-neoplastic conditions of the lower gastrointestinal tract. 下胃肠道肿瘤和非肿瘤条件下的脱细胞粘蛋白。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.106672
Noureldien Darwish, Lynn Guo, Eundong Park, Hwajeong Lee
{"title":"Acellular mucin in neoplastic and non-neoplastic conditions of the lower gastrointestinal tract.","authors":"Noureldien Darwish, Lynn Guo, Eundong Park, Hwajeong Lee","doi":"10.4240/wjgs.v17.i7.106672","DOIUrl":"10.4240/wjgs.v17.i7.106672","url":null,"abstract":"<p><p>Acellular mucin refers to pools of mucin without epithelial component, oftentimes harboring inflammatory cells. Acellular mucin can be observed in both neoplastic and non-neoplastic lower gastrointestinal (GI) conditions. While mucinous neoplasms are classified and staged using established guidelines, interobserver variability occurs when acellular mucin pools are encountered, leading to inconsistent interpretation and staging. In particular, acellular mucin found in regional lymph nodes of colorectal adenocarcinoma patients who have not received treatment presents a diagnostic challenge, as its prognostic implication is not clearly defined. Acellular mucin is also commonly seen in treated colorectal adenocarcinoma, post neoadjuvant therapy. Although acellular mucin is not counted toward T or N staging in this setting, variation in how pathologists report and stage these cases persists. Acellular mucin can also be seen in non-neoplastic specimens, such as those from interval appendectomies, appendiceal diverticula, colonic diverticulitis, volvulus, and Crohn's disease where it may mimic a neoplastic lesion. Acellular mucin in this setting is often a byproduct of inflammation, increased luminal pressure, and mural defect. This review highlights the clinical relevance and diagnostic complexity of acellular mucin in pathologic conditions of the lower GI tract. Further studies are needed to clarify its prognostic value and develop standardized guidelines.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"106672"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cholecystitis with gallbladder rupture leading to free gallstone migration causing chronic abdominal wall sinus formation: A case report. 胆囊炎伴胆囊破裂,胆囊结石游离迁移,引起慢性腹壁窦形成1例。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.105308
Liu Yang, Tao Wang, Xiu-Li Li, Yan-Li Wang
{"title":"Cholecystitis with gallbladder rupture leading to free gallstone migration causing chronic abdominal wall sinus formation: A case report.","authors":"Liu Yang, Tao Wang, Xiu-Li Li, Yan-Li Wang","doi":"10.4240/wjgs.v17.i7.105308","DOIUrl":"10.4240/wjgs.v17.i7.105308","url":null,"abstract":"<p><strong>Background: </strong>Gallstones are frequently observed in patients with cholecystitis, but the migration of free gallstones into the abdominal wall leading to chronic sinus formation is exceedingly rare.</p><p><strong>Case summary: </strong>We report a case of a 72-year-old woman who experienced recurring fever and abdominal pain following laparoscopic cholecystectomy for acute cholecystitis, during which gallbladder rupture was noted. Despite initial conservative management and temporary T-tube placement, the patient developed a chronic sinus in the abdominal wall 9.5 years later, characterized by an area of thickened soft tissue with ulceration and purulent discharge. Surgical exploration revealed the presence of a migrated gallstone at the base of the sinus tract, necessitating careful surgical removal and postoperative wound care.</p><p><strong>Conclusion: </strong>This case highlights the potential long-term complications of retained free gallstones and the importance of thorough surgical retrieval.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"105308"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting neoadjuvant chemoradiotherapy response in rectal cancer: Insights from biomarkers to clinical practice. 预测直肠癌的新辅助放化疗反应:从生物标志物到临床实践的见解。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.106724
Hikmet Pehlevan-Özel, Eda Şahingöz, Mert Altaş, Mesut Tez
{"title":"Predicting neoadjuvant chemoradiotherapy response in rectal cancer: Insights from biomarkers to clinical practice.","authors":"Hikmet Pehlevan-Özel, Eda Şahingöz, Mert Altaş, Mesut Tez","doi":"10.4240/wjgs.v17.i7.106724","DOIUrl":"10.4240/wjgs.v17.i7.106724","url":null,"abstract":"<p><p>Rectal cancer poses a major global health challenge, with neoadjuvant chemoradiotherapy improving outcomes in locally advanced cases by reducing tumor burden and recurrence risk. However, response variability, including only 15%-20% of patients achieving pathological complete response, underscores the urgent need for accurate predictive tools. This review explored current and emerging biomarkers to enhance neoadjuvant chemoradiotherapy response prediction and inform clinical practice.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"106724"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation and analysis of 3-year survival and influencing factors in patients with primary gastric cancer. 原发性胃癌患者3年生存率及影响因素调查分析。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-07-27 DOI: 10.4240/wjgs.v17.i7.103938
Jin Gan, Xiong Yu, Xin-Xing Duan
{"title":"Investigation and analysis of 3-year survival and influencing factors in patients with primary gastric cancer.","authors":"Jin Gan, Xiong Yu, Xin-Xing Duan","doi":"10.4240/wjgs.v17.i7.103938","DOIUrl":"10.4240/wjgs.v17.i7.103938","url":null,"abstract":"<p><strong>Background: </strong>This study explores the 3-year survival outcomes and associated influencing factors in patients with primary gastric cancer treated <i>via</i> laparoscopic surgery, providing meaningful guidance for clinical management.</p><p><strong>Aim: </strong>To evaluate and analyze the 3-year survival outcomes and associated risk factors in patients with primary gastric cancer who underwent laparoscopic surgery.</p><p><strong>Methods: </strong>A total of 100 patients with primary gastric cancer who underwent laparoscopic surgery at our hospital between January 2019 and December 2021 were enrolled. These patients were monitored for 3 years, and their survival statuses were recorded. Patients were categorized into survival and non-survival groups based on their outcomes. Data on sex, age, American Society of Anesthesiologists classification, tumor size, depth of invasion, postoperative adjuvant radio-chemotherapy, postoperative carcinoembryonic antigen (CEA) levels, and other clinical parameters were collected and contrasted across groups to identify factors impacting 3-year survival.</p><p><strong>Results: </strong>After a 3-year follow-up, the survival rate was 73.00% (73 of 100 patients). No significant differences were observed in sex, tumor location, alcohol consumption, smoking status, tumor differentiation, histological type, intraoperative blood loss, or surgical outcomes between patients with varying prognoses (<i>P</i> > 0.05). However, notable disparities were found in age, American Society of Anesthesiologists classification, tumor-node-metastasis (TNM) stage, tumor size, depth of invasion, lymph node metastasis, lymph node dissection, postoperative adjuvant radio-chemotherapy, postoperative CEA levels, surgical duration, extent of gastric resection, and postoperative complications (<i>P</i> < 0.05). Multivariate logistic regression analysis identified age, TNM stage, tumor size, depth of invasion, lymph node metastasis, lymph node dissection, postoperative adjuvant radio-chemotherapy, postoperative CEA levels, surgical duration, extent of gastric resection, and postoperative complications as independent predictors of 3-year survival in patients with primary gastric cancer following laparoscopic surgery (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The 3-year survival outcome for patients undergoing laparoscopic surgery for primary gastric cancer was 73.00%. Key determinants of survival included age, TNM stage, tumor size, depth of invasion, and lymph node metastasis. This analysis of 3-year survival and its influencing factors offers novel perspectives for optimizing clinical interventions in patients with primary gastric cancer treated <i>via</i> laparoscopic surgery.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 7","pages":"103938"},"PeriodicalIF":1.7,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信