World Journal of Gastrointestinal Surgery最新文献

{"title":"Early identification and multidisciplinary management of immune checkpoint inhibitors associated colitis can improve patient outcomes.","authors":"Liang Wang, Sheng-Mei Zhang, Xiao-Qian Chen","doi":"10.4240/wjgs.v17.i1.99122","DOIUrl":"10.4240/wjgs.v17.i1.99122","url":null,"abstract":"<p><p>Currently, the use of immune checkpoint inhibitors (ICIs) has shown notable clinical efficacy in treating various malignant tumors, significantly improving patient prognosis. However, while ICIs enhance the body's anti-tumor effects, they can also trigger immune-related adverse events (irAEs), with ICI-associated colitis being one of the more prevalent forms. This condition can disrupt treatment, necessitate drug discontinuation, and adversely affect therapeutic outcomes. In severe cases, irAEs may even become life-threatening. A recent case report by Hong <i>et al</i> highlights the importance of vigilance for ICI-associated colitis in patients experiencing symptoms such as diarrhea and abdominal pain, which can arise both during and even after completion of ICI treatment. Early identification, multidisciplinary management, and continuous monitoring of patients are essential steps to further improve outcomes.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"99122"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of nalbuphine on analgesia and pain factors after gastric cancer resection.","authors":"Jia-Li Qian, Jie Wang, Zi-Yi Shen, Bao-Qin Xu, Dan-Ping Shen, Cheng Yang","doi":"10.4240/wjgs.v17.i1.99327","DOIUrl":"10.4240/wjgs.v17.i1.99327","url":null,"abstract":"<p><strong>Background: </strong>Gastric cancer (GC) is a prevalent tumor in the digestive system, with around one million new cases reported annually, ranking it as the third most common malignancy. Reducing pain is a key research focus. This study evaluates the effect of nalbuphine on the analgesic effect and the expression of pain factors in patients after radical resection.</p><p><strong>Aim: </strong>To provide a reference for postoperative analgesia methods.</p><p><strong>Methods: </strong>One hundred eight patients with GC, admitted between January 2022 and June 2024, underwent radical gastrectomy. They received a controlled analgesia pump and a transverse abdominis muscle plane block, divided into two groups of 54 patients in each group. The control group received sufentanil, while the observation group received nalbuphine as an analgesic. Postoperative analgesic effects, pain factor expression, and adverse effects were compared.</p><p><strong>Results: </strong>The resting pain and activity pain scores in the observation group at 6, 12, 24 and 48 hours were significantly lower than those in the control group. Additionally, the number of presses and consumption of the observation group at 48 hours were lower than those of the control group; and the response rate of the observation group was higher than that of the control group (<i>P</i> < 0.05). The prostaglandin E2, substance P, and serotonin levels 24 hours after the observation group were lower than those in the control group, and the incidence of adverse reactions was 5.56% lower than 22.22% in the control group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The findings suggest that nalbuphine enhances postoperative multimodal analgesia in patients with radical GC, effectively improving postoperative analgesic effect, relieving postoperative resting and active pain, and reducing postoperative pain factor expression, demonstrating its potential for clinical application.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"99327"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal bleeding after pancreatoduodenectomy: Report of four cases.","authors":"Zi-Jin Liu, Jia-Yi Hong, Chao Zhang, Jing She, Hui-Hong Zhai","doi":"10.4240/wjgs.v17.i1.100119","DOIUrl":"10.4240/wjgs.v17.i1.100119","url":null,"abstract":"<p><strong>Background: </strong>Postpancreatectomy hemorrhage is one of the most severe and life-threatening complications after pancreaticoduodenectomy. We present four cases of gastrointestinal bleeding patients to clarify its appropriate treatment and prevention.</p><p><strong>Case summary: </strong>The main symptoms included black stool, hematochezia, haematemesis, blood in the nasogastric tube, and hemorrhagic shock. The mean age was 66.25 years old and the median onset time was 340 d after the surgery. The bleeding location comprised gastrointestinal anastomosis, bile duct-jejunum anastomosis, and extraluminal bleeding. The possible causes included marginal ulcer, jejunal varix, and abdominal infection. Endoscopic hemostatic clips, as well as a covered stent using angiography, were utilized to stop the bleeding and three patients survived. Only one patient died of gastrointestinal bleeding, abdominal bleeding, abdominal infection, hypovolemic shock, and disseminated intravascular coagulation.</p><p><strong>Conclusion: </strong>Early and effective endoscopic intervention is the key to successful hemostasis in patients with gastrointestinal bleeding after pancreatoduodenectomy.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"100119"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical application of indocyanine green fluorescence imaging in laparoscopic cholecystectomy with common bile duct exploration and J-Tube drainage.","authors":"Zi-Han Wang, Shuai Yan, Rui Wang, Lin Chen, Jin-Zhu Wu, Wei-Hua Cai","doi":"10.4240/wjgs.v17.i1.99495","DOIUrl":"10.4240/wjgs.v17.i1.99495","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Intraoperative and postoperative biliary injuries remain significant complications of laparoscopic common bile duct exploration (LCBDE). Indocyanine green (ICG) has been shown to significantly reduce injuries caused by intraoperative operational errors. We found that the J-tube can reduce postoperative strictures and injuries to the common bile duct. At this moment, we aim to analyze and compare the complications, efficacy, short-term outcomes, and feasibility of these two adjunctive tools for LCBDE.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To evaluate the efficacy of ICG fluorescence imaging In LCBDE and J-tube drainage for patients with common bile duct stones.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We retrospectively collected the clinical case data of patients who were treated at the Hepatobiliary Surgery Department of the Third People's Hospital of Nantong, affiliated with Nantong University, from January 2016 to January 2021 due to gallbladder stones with choledocholithiasis and who underwent LCBDE combined with a primary suture and either J-tube or T-tube drainage. The patients were divided into groups: Traditional white-light laparoscopy + T-tube group (WL + T-tube), traditional WL + J-tube group, fluorescent laparoscopy + T-tube group (ICG + T-tube) and fluorescent laparoscopy + J-tube group (ICG + J-tube). The preoperative and postoperative clinical case data, laboratory examination data, and intraoperative and postoperative complications (including postoperative bile leakage, electrolyte disturbances, biliary peritonitis, and postoperative infections) and other relevant indicators were compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 198 patients (112 males and 86 females) were included in the study, with 74 patients in the WL + T-tube, 47 in the WL + J-tube, 42 in the ICG + T-tube, and 35 in the ICG + J-tube. Compared with the other groups, the ICG + J had significantly shorter operation time (114 minutes, &lt;i&gt;P&lt;/i&gt; = 0.001), less blood loss (42 mL, &lt;i&gt;P&lt;/i&gt; = 0.02), shorter postoperative hospital stays (7 days, &lt;i&gt;P&lt;/i&gt; = 0.038), and lower surgical costs (China yuan 30178, &lt;i&gt;P&lt;/i&gt; = 0.001). Furthermore, patients were subdivided into two groups based on whether a T-tube or J-tube was placed during the surgery. By the third postoperative day, the aspartate transaminase, glutamic pyruvic transaminase, total bilirubin, and direct bilirubin levels were lower in the J-tube group than in the T-tube group (&lt;i&gt;P&lt;/i&gt; &lt; 0.001). At last, follow-up observations showed that the incidence of biliary strictures at three months postoperatively was significantly lower in the J-tube group than in the T-tube group (&lt;i&gt;P&lt;/i&gt; = 0.002).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;ICG fluorescence imaging in laparoscopic cholecystectomy with common bile duct exploration and J-tube drainage facilitates rapid identification of biliary anatomy and variations, reducing intraoperative bile duct injury, blood loss, surgery duration, and postoperative bile ","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"99495"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic inhibition of colorectal cancer progression by silencing Aurora A and the targeting protein for Xklp2.","authors":"Gui-Xian Sheng, Yu-Jia Zhang, Tao Shang","doi":"10.4240/wjgs.v17.i1.97148","DOIUrl":"10.4240/wjgs.v17.i1.97148","url":null,"abstract":"<p><strong>Background: </strong>Unraveling the pathogenesis of colorectal cancer (CRC) can aid in developing prevention and treatment strategies. Aurora kinase A (AURKA) is a key participant in mitotic control and interacts with its co-activator, the targeting protein for Xklp2 (TPX2) microtubule nucleation factor. AURKA is associated with poor clinical outcomes and high risks of CRC recurrence. AURKA/TPX2 co-overexpression in cancer may contribute to tumorigenesis. Despite its pivotal role in CRC development and progression, the action mechanism of AURKA remains unclear. Further research is needed to explore the complex interplay between AURKA and TPX2 and to develop effective targeted treatments for patients with CRC.</p><p><strong>Aim: </strong>To compare effects of AURKA and TPX2 and their combined knockdown on CRC cells.</p><p><strong>Methods: </strong>We evaluated three CRC gene datasets about CRC (GSE32323, GSE25071, and GSE21510). Potential hub genes associated with CRC onset were identified using the Venn, search tool for the retrieval of interacting genes, and KOBAS platforms, with AURKA and TPX2 emerging as significant factors. Subsequently, cell models with knockdown of AURKA, TPX2, or both were constructed using SW480 and LOVO cells. Quantitative real-time polymerase chain reaction, western blotting, cell counting kit-8, cell cloning assays, flow cytometry, and Transwell assays were used.</p><p><strong>Results: </strong>Forty-three highly expressed genes and 39 poorly expressed genes overlapped in cancer tissues compared to controls from three datasets. In the protein-protein interaction network of highly expressed genes, AURKA was one of key genes. Its combined score with TPX2 was 0.999, and their co-expression score was 0.846. In CRC cells, knockdown of AURKA, TPX2, or both reduced cell viability and colony number, while blocking G0/G1 phase and enhancing cell apoptosis. Additionally, they were weakened cell proliferation and migration abilities. Furthermore, the expression levels of B-cell lymphoma-2-Associated X, caspase 3, and tumor protein P53, and E-cadherin increased with a decrease in B-cell lymphoma-2, N-cadherin, and vimentin proteins. These effects were amplified when both AURKA and TPX2 were concurrently downregulated.</p><p><strong>Conclusion: </strong>Combined knockdown of AURKA and TPX2 was effective in suppressing the malignant phenotype in CRC. Co-inhibition of gene expression is a potential developmental direction for CRC treatment.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"97148"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Petersen's hernia with chylous ascites following laparoscopic total gastrectomy and Roux-en-Y anastomosis: A case report and review of literature.","authors":"Shi-Fu Hu, Yuan-Yuan Hao, Xiang-Yu Liu, Han-Bo Liu","doi":"10.4240/wjgs.v17.i1.97975","DOIUrl":"10.4240/wjgs.v17.i1.97975","url":null,"abstract":"<p><strong>Background: </strong>Petersen's hernia occurring through the epiploic foramen of the greater omentum, is an uncommon type of internal hernia. When it presents with complications such as chylous ascites, which is the lymphatic fluid accumulation in the abdominal cavity, it is particularly rare. Following laparoscopic total gastrectomy and Roux-en-Y anastomosis, the incidence of this condition is exceedingly low.</p><p><strong>Case summary: </strong>A 62-year-old male patient developed Petersen's hernia following laparoscopic total gastrectomy (LTG) for gastric cancer, after Roux-en-Y anastomosis. Intestinal torsion and obstruction were experienced by the patient, along with a small amount of chylous ascites. Imaging studies and clinical assessment confirmed the diagnosis. Emergency surgery was performed promptly for the patient in the operating room. The twisted small intestine was reduced and the defect in Petersen's space was repaired. The procedure was successful in the correction of the intestinal torsion and approximation of the hernia without the need for bowel resection. The patient's condition significantly improved following the surgery. The ascites evolved from a milky white appearance to a pale yellow, with a substantial decrease in the triglyceride levels in the ascitic fluid, implying a favorable recovery trajectory. The patient was monitored closely and received appropriate care postoperatively, including nutritional support and fluid management.</p><p><strong>Conclusion: </strong>This report illustrates the significance of recognizing Petersen's hernia as a potential complication following gastrectomy for gastric cancer. It highlights the fundamental role of early surgical intervention in the effective management of such complications. The favorable outcome in this patient illustrates that prompt and appropriate surgical management can deter the necessity for more extensive procedures such as bowel resection.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"97975"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary duodenal T/histiocyte-rich large B-cell lymphoma complicated with obstructive jaundice: A case report and review of literature.","authors":"Xing-Yu Chen, Jia-Yi Yang, Yi-Hua Chen, A-Niu Liu, Shan-Shan Wu, Se-Niu Ji Zhi, Shu-Mei Zheng","doi":"10.4240/wjgs.v17.i1.99758","DOIUrl":"10.4240/wjgs.v17.i1.99758","url":null,"abstract":"<p><strong>Background: </strong>T/histiocyte-rich large B-cell lymphoma (T/HRBCL) is a highly aggressive subtype of diffuse large B-cell lymphoma characterized histologically by the presence of a few neoplastic large B cells amidst an abundant background of reactive T lymphocytes and/or histiocytes. T/HRBCL commonly affects the lymph nodes, followed by extranodal sites, such as the spleen, liver, and bone marrow, with rare occurrences in the gastrointestinal tract. Primary gastrointestinal T/HRBCL lacks specific clinical and endoscopic manifestations, and it is difficult to differentiate from inflammatory diseases, nodular lymphocyte predominant Hodgkin lymphoma, and other diseases on a histological basis, thereby hindering early diagnosis.</p><p><strong>Case summary: </strong>A 63-year-old man was hospitalized with a one-month history of jaundice and weight loss of approximately 3 kg. Laboratory tests revealed increased hepatic parameters in a cholestatic pattern and elevated carbohydrate antigen 19-9 levels. An abdominal computed tomography scan revealed a low-density mass within the descending duodenum and dilation of the bile and pancreatic ducts. He was clinically diagnosed with a duodenal tumor. During surgery, a 7.0 cm × 8.0 cm mass was identified within the descending duodenum, so pancreaticoduodenectomy and cholecystectomy were performed. Following operative biopsy, the tumor was diagnosed as primary duodenal T/HRBCL. The patient refused postoperative chemotherapy and died four months after surgery.</p><p><strong>Conclusion: </strong>Primary duodenal T/HRBCL is an extremely rare and highly aggressive malignancy. The initial treatment strategies should be based on the original site of the tumor, the disease stage, and the patient's physical condition. Chemotherapy-based comprehensive treatment is still the main treatment method for primary gastrointestinal T/HRBCL.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"99758"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive pancreaticoduodenectomy: A bibliometric method applied to the top one hundred cited articles.","authors":"Jia-Jie Feng, Yi-Wen Zhao, Hong-Yin Liang, Ke-Xin Jiang, Rui-Wu Dai","doi":"10.4240/wjgs.v17.i1.100291","DOIUrl":"10.4240/wjgs.v17.i1.100291","url":null,"abstract":"<p><strong>Background: </strong>Minimally invasive pancreaticoduodenectomy (MIPD) is considered one of the most complex procedures in general surgery. The number of articles on MIPD has been increasing annually. However, published reports often have complex research directions, and the focal points frequently change. Therefore, a comprehensive review and organization of the literature in this field is necessary.</p><p><strong>Aim: </strong>To summarize current research, predict future hotspots and trends, and provide insights for MIPD development.</p><p><strong>Methods: </strong>To conduct the study, the Web of Science Core Collection was searched for relevant articles. The analysis focused on the top 100 articles in the field. Two widely used bibliometric tools, CiteSpace and VOSviewer, were used to examine various aspects, including research directions, authors, countries, institutions, journals, and keywords.</p><p><strong>Results: </strong>The top 100 articles were published between 2005 and 2022, with the majority originating from the United States (<i>n</i> = 51). Among the contributing institutions, Pancreas Center of the University of Chicago and the Health System of the University of Chicago had the highest number of publications (<i>n</i> = 17). In terms of individual authors, \"Zeh HJ\" and \"Zureikat AH\" led with 13 articles each. The high-frequency keywords in the literature encompassed three main areas: Surgical modality, perioperative outcomes, and the learning curve. These keywords were further categorized into seven primary clusters, with the largest being \"laparoscopic pancreaticoduodenectomy\".</p><p><strong>Conclusion: </strong>The most influential studies predominantly originate from the United States, and there is growing interest in robotic surgery. Despite MIPD's potential benefits, further research is required to address technical challenges and improve outcomes.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"100291"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of DynaCT biliary soft tissue reconstruction technology in diagnosis and treatment of hepatolithiasis.","authors":"Yong-Qing Ye, Pei-Heng Li, Zhao-Wei Ding, Sheng-Feng Zhang, Rong-Qi Li, Ya-Wen Cao","doi":"10.4240/wjgs.v17.i1.98283","DOIUrl":"10.4240/wjgs.v17.i1.98283","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Hepatobiliary stone disease involves an intrahepatic bile duct stone that occurs above the confluence of the right and left hepatic ducts. One-step percutaneous transhepatic cholangioscopic lithotripsy (PTCSL) using the percutaneous transhepatic one-step biliary fistulation (PTOBF) technique enables the clearing of intrahepatic stones and the resolution of strictures. However, hepatolithiasis with associated strictures still has high residual and recurrence rates after one-step PTCSL. DynaCT can achieve synchronized acquisition with a flat-panel detector during C-arm rotation. The technical approach and application value of DynaCT biliary soft tissue reconstruction technology for the diagnosis and treatment of hepatolithiasis with bile duct stenosis were evaluated in this study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To explore the value of DynaCT biliary soft tissue reconstruction technology for the diagnosis and treatment of hepatolithiasis with bile duct stenosis, and to assess the feasibility and effectiveness of the PTOBF technique guided by DynaCT biliary soft tissue reconstruction technology.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The clinical data of 140 patients with complex biliary stenosis disease combined with bile duct stenosis who received PTOBF and were admitted to the First Affiliated Hospital of Guangzhou Medical University from January 2020 to December 2024 were collected. The patients were divided into two groups: DynaCT-PTOBF group (70 patients) and conventional PTOBF group (70 patients). These groups were compared in terms of the preoperative bile duct stenosis, location of the liver segment where the stone was located, intraoperative operative time, immediate stone retrieval rate, successful stenosis dilatation rate, postoperative complication rate, postoperative reoperation rate, stone recurrence rate, and stenosis recurrence rate.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;DynaCT biliary soft tissue reconstruction technology was successfully performed in 70 patients. The DynaCT-PTOBF group had a higher detection rate of target bile ducts where bile duct stones and biliary strictures were located than the PTOBF group. Compared with the PTOBF group, the DynaCT-PTOBF group was characterized by a significantly greater immediate stone removal rate (68.6% &lt;i&gt;vs&lt;/i&gt; 50.0%, &lt;i&gt;P&lt;/i&gt; = 0.025), greater immediate stenosis dilatation success rate (72.9% &lt;i&gt;vs&lt;/i&gt; 55.7%, &lt;i&gt;P&lt;/i&gt; = 0.034), greater final stenosis release rate (91.4% &lt;i&gt;vs&lt;/i&gt; 75.7%, &lt;i&gt;P&lt;/i&gt; = 0.012), shorter duration of intraoperative hemorrhage (3.14 ± 2.00 &lt;i&gt;vs&lt;/i&gt; 26.5 ± 52.1, &lt;i&gt;P&lt;/i&gt; = 0.039), and lower incidence of distant cholangitis (2.9% &lt;i&gt;vs&lt;/i&gt; 11.4%, &lt;i&gt;P&lt;/i&gt; = 0.49). There were no significant differences between the two groups in terms of the final stone removal rate, reoperation rate, or long-term complication incidence rate.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;DynaCT biliary soft tissue reconstruction technology guiding the PTOBF technique in patient","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"98283"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feeding jejunostomy in post-gastrectomy nutrition management for gastric cancer.","authors":"Mushtaq Chalkoo, Mudasir Habib, Mohd Yaqoob Bhat","doi":"10.4240/wjgs.v16.i12.3887","DOIUrl":"10.4240/wjgs.v16.i12.3887","url":null,"abstract":"<p><p>Patients undergoing gastric resection for stomach cancer are at an increased risk of malnutrition. Early postoperative enteral feeding significantly improves nutritional status and reduces morbidity. The use of a feeding jejunostomy in a selected group of these patients does improve the outcome.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 12","pages":"3887-3889"},"PeriodicalIF":1.8,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}