World Journal of Gastrointestinal Surgery最新文献

{"title":"Effects of gastrointestinal motility therapy combined with acupuncture on gastrointestinal function in patients after laparoscopic radical surgery.","authors":"Chen Liang, Feng-Xi Qiu, Xiao-Cun Zhang, Qi-Long Hu","doi":"10.4240/wjgs.v17.i6.104325","DOIUrl":"10.4240/wjgs.v17.i6.104325","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal (GI) dysfunction is common after laparoscopic radical gastrectomy for gastric cancer and affects rehabilitation. While conventional treatments can alleviate symptoms to a certain extent, they often fail to fully address the issue of insufficient GI motility. The GI motility therapeutic apparatus promotes dynamic recovery by simulating GI electric waves, whereas acupuncture regulates zang-fu qi movement, both offering effective interventions. However, there are few clinical studies investigating the combined use of GI motility therapy and acupuncture to promote GI function recovery in patients after GI laparoscopic radical surgery.</p><p><strong>Aim: </strong>To evaluate the effects of combining GI motility therapy devices with acupuncture on GI function in patients undergoing radical laparoscopic surgery.</p><p><strong>Methods: </strong>This retrospective study included 196 patients who underwent radical GI endoscopic surgery at the Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, from June 2022 to May 2024. Patients were classified into a normal group (conventional treatment, <i>n</i> = 96) and an integrated group (conventional + GI motility therapy device + acupuncture, <i>n</i> = 100). The effects on GI function, hormone levels pre- and post-treatment, GI symptoms, immune function, adverse reactions, and patient satisfaction in both groups were assessed.</p><p><strong>Results: </strong>Compared with the normal group, the integrated group demonstrated significantly better overall effectiveness (93.00% <i>vs</i> 84.3%; <i>P</i> < 0.05) and shorter durations for first exhaust, feeding, defecation, and hospital stay (<i>P</i> < 0.05). Post-treatment, the integrated group had lower gastrin and GI symptom rating scale scores and higher motilin, vasoactive intestinal peptide, and immune marker (CD3+, CD4+, CD4+/CD8+, and natural killer cells) levels (<i>P</i> < 0.05). The integrated group, compared to the normal group, also reported fewer adverse reactions (5.00% <i>vs</i> 14.58%) and higher patient satisfaction (97.00% <i>vs</i> 84.38%), both statistically significant (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The combination of a GI motility therapy device and acupuncture promotes GI function recovery after radical gastrectomy, regulates GI hormones and immune function, and is safe and effective.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 6","pages":"104325"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant transverse colonic mesenteric mucinous liposarcoma combined with rectal cancer and aortic coarctation: A case report and review of literature.","authors":"Meng Wang, Jian Sun, Zhi-Qiang Song, Xi-Qi Chen, Guang-Dong Xie, Yong Zhu, Yong-Kun Zhou","doi":"10.4240/wjgs.v17.i6.107866","DOIUrl":"10.4240/wjgs.v17.i6.107866","url":null,"abstract":"<p><strong>Background: </strong>Liposarcomas (LPSs) are malignant mesenchymal tumors originating from adipocytes. Myxoid LPS (MLPS), a common subtype, predominantly arises in the extremities, retroperitoneum, and deep soft tissues, with a rare occurrence in the gastrointestinal tract. Primary mesenteric LPS is particularly uncommon, especially in the transverse colonic mesentery.</p><p><strong>Case summary: </strong>This report describes the case of a 65-year-old female patient who presented with abdominal distension and was diagnosed with a giant mucinous LPS of the transverse colonic mesentery. Upon admission, the patient underwent a comprehensive evaluation. Contrast-enhanced computed tomography (CT) of the chest and abdomen revealed a large malignant tumor with aortic dissection, while colonoscopy identified rectal cancer. Given the patient's condition and surgical risk, an interventional procedure was first performed to manage the aortic coarctation, followed by tumor resection <i>via</i> laparotomy. Intraoperative and histopathological findings confirmed a giant mucinous LPS originating from the transverse colon mesentery. Postoperatively, the patient underwent chemotherapy and regular follow-up CT. Although the rectal tumor did not recur, the mesenteric tumor showed extensive recurrence, compressing the intestinal lumen and causing mechanical obstruction, which severely threatened the patient's life. A second operation temporarily relieved the obstructive symptoms; however, it had a limited effect on tumor progression. The patient died four months later due to disease progression.</p><p><strong>Conclusion: </strong>While no standardized treatment exists for MLPS co-occurring with multiple diseases, operation remains the mainstay. However, recurrence, metastasis, and poor postoperative prognosis continue to pose serious threats to patient survival.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 6","pages":"107866"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term survival with multimodal treatment including conversion surgery for locally advanced esophageal neuroendocrine carcinoma: A case report.","authors":"Kazuya Okamoto, Kentoku Fujisawa, Kei Kono, Yusuke Ogawa, Hayato Shimoyama, Shusuke Haruta, Yutaka Takazawa, Masaki Ueno, Harushi Udagawa","doi":"10.4240/wjgs.v17.i6.107086","DOIUrl":"10.4240/wjgs.v17.i6.107086","url":null,"abstract":"<p><strong>Background: </strong>Esophageal neuroendocrine carcinoma (NEC), a rare and aggressive malignancy with a poor prognosis, is often diagnosed at an advanced stage. The optimal treatment strategy for locally advanced and recurrent esophageal NEC remains unclear, and conversion surgery has only been reported for a few cases. Herein, we present the case of a 66-year-old male with locally advanced esophageal NEC initially diagnosed as squamous cell carcinoma.</p><p><strong>Case summary: </strong>The patient underwent induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil, followed by conversion surgery, including subtotal esophagectomy, three-field lymph node dissection, and distal pancreatectomy with splenectomy, due to infiltration of the pancreas by the No. 11p lymph node. Postoperative pathological findings revealed a large cell-type NEC without a squamous cell carcinoma component, suspected to be a mixed neuroendocrine/non-neuroendocrine neoplasm. Hepatic metastasis was diagnosed within one month of surgery. Despite the administration of four courses of irinotecan + cisplatin chemotherapy, the treatment effect was considered a 'progressive disease'. After a multidisciplinary discussion, the patient underwent partial liver resection, followed by second-line chemotherapy with amrubicin. The patient achieved three-year survival with no new recurrence.</p><p><strong>Conclusion: </strong>This case highlights the potential of multimodal treatment for long-term survival in advanced esophageal NEC.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 6","pages":"107086"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for recurrence of primary sclerosing cholangitis in pediatric liver transplant recipients: A meta-analysis.","authors":"Bei Sun, Dong Guan, Yu-Geng Gao, Jing-Yi Chen, Yi-Hui Rong, Zuo-Ming Guo","doi":"10.4240/wjgs.v17.i6.103867","DOIUrl":"10.4240/wjgs.v17.i6.103867","url":null,"abstract":"<p><strong>Background: </strong>Primary sclerosing cholangitis (PSC) is a long-term liver condition defined by the inflammation and scarring of the bile ducts, resulting in complications such as liver cirrhosis, portal hypertension, and cholangiocarcinoma. Although PSC predominantly affects adults, the incidence in pediatric patients is rising. For individuals in the advanced stages of liver disease, liver transplantation (LT) is the sole curative treatment option. However, the recurrence of PSC in the transplanted liver, known as recurrent PSC (rPSC), remains a significant concern.</p><p><strong>Aim: </strong>To identify the potential risk factors for the recurrence of PSC in pediatric patients after undergoing LT.</p><p><strong>Methods: </strong>A literature search was carried out across databases, including PubMed, Embase, Cochrane Library, and Scopus, covering studies published from 1990 through 2024. The Newcastle-Ottawa scale was utilized to assess the quality of the selected studies. Statistical analyses were conducted using RevMan 5.3 software, where the risk of recurrence was quantified using hazard ratios (HR) with 95%CI.</p><p><strong>Results: </strong>A total of nine reports with 2524 pediatric patients with PSC were included in this analysis. The findings revealed several important risk factors connected to the rPSC in pediatric patients who had received a liver transplant, including concurrent inflammatory bowel disease (IBD), elevated liver enzyme levels, and the presence of PSC-autoimmune hepatitis (AIH) overlap syndrome (all <i>P</i> < 0.05). No statistically significant association was found between acute allograft rejection, Epstein-Barr virus infection, and the risk of rPSC recurrence in the pediatric liver transplant recipients.</p><p><strong>Conclusion: </strong>The present systematic review and meta-analysis have identified various risk factors associated with the recurrence of PSC in pediatric patients who underwent LT, including IBD, elevated liver enzyme levels, and PSC-AIH overlap syndrome.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 6","pages":"103867"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence, risk factors and outcomes for post-hepatectomy portal vein thrombosis: A retrospective study.","authors":"Jian-Ping Song, Ming Xiao, Ji-Ming Ma, Shang Zhang, Liu-Qing Yang, Zhi-Shuo Wang, Can-Hong Xiang","doi":"10.4240/wjgs.v17.i6.104729","DOIUrl":"10.4240/wjgs.v17.i6.104729","url":null,"abstract":"<p><strong>Background: </strong>Post-hepatectomy portal vein thrombosis (PH-PVT) is a life-threatening complication; however, the available literature on this topic is limited.</p><p><strong>Aim: </strong>To examine the incidence, risk factors, and outcomes associated with PH-PVT.</p><p><strong>Methods: </strong>Medical records of patients who underwent hepatic resection for various diseases between February 2014 and December 2023 at Beijing Tsinghua Changgung Hospital affiliated with Tsinghua University (Beijing, China) were retrospectively reviewed. The patients were divided into a PH-PVT group and a non-PH-PVT group. Univariate and multivariate logistic regression analyses were performed to identify the risk factors for PH-PVT.</p><p><strong>Results: </strong>A total of 1064 patients were included in the study cohort, and the incidence and mortality rates of PH-PVT were 3.9% and 35.7%, respectively. The median time from hepatectomy to the diagnosis of PH-PVT was 6 days. Multivariate analysis revealed that hepatectomy combined with pancreaticoduodenectomy (HPD) [odds ratio (OR) = 7.627 (1.390-41.842), <i>P</i> = 0.019], portal vein reconstruction [OR = 6.119 (2.636-14.203), <i>P</i> < 0.001] and a postoperative portal vein angle < 100° [OR = 2.457 (1.131-5.348), <i>P</i> = 0.023] were independent risk factors for PH-PVT. Age ≥ 60 years [OR = 8.688 (1.774-42.539), <i>P</i> = 0.008] and portal vein reconstruction [OR = 6.182 (1.246-30.687), <i>P</i> = 0.026] were independent risk factors for mortality in PH-PVT patients.</p><p><strong>Conclusion: </strong>Portal vein reconstruction, a postoperative portal vein angle < 100° and HPD were independent risk factors for PH-PVT. Age ≥ 60 years and portal vein reconstruction were independent risk factors for mortality in PH-PVT patients.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 6","pages":"104729"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound elastography for the differential diagnosis of benign and malignant gastrointestinal stromal tumors.","authors":"Hao Xu, Jiao-Ran Liu, Bo-Jian Gao, Long Peng, Zhi-Qin Han, Rong-Xin Zhang","doi":"10.4240/wjgs.v17.i6.103674","DOIUrl":"10.4240/wjgs.v17.i6.103674","url":null,"abstract":"<p><strong>Background: </strong>Preoperative distinguishing between benign and malignant gastrointestinal stromal tumors (GISTs) poses a challenge. Ultrasound elastography has emerged as a promising diagnostic tool; however, further investigation is needed to assess its diagnostic accuracy in evaluating GISTs.</p><p><strong>Aim: </strong>To evaluate the accuracy of ultrasound elastography for differentiating between benign and malignant GISTs.</p><p><strong>Methods: </strong>This prospective study included 110 patients with 103 histopathologically confirmed GISTs between January 2021 and December 2023. All tumors underwent conventional ultrasound examination, strain elastography (SE), and shear-wave elastography (SWE) before surgical resection. The study evaluated elastographic parameters such as strain ratio, elastographic patterns, mean elastic modulus, and heterogeneity index. Diagnostic performance was evaluated using receiver operating characteristic curve analysis, with histopathological diagnosis as the reference standard.</p><p><strong>Results: </strong>Of the 103 GISTs, 45 (43.7%) were benign and 58 (56.3%) were malignant based on modified National Institutes of Health criteria. Malignant GISTs exhibited significantly higher strain ratios (4.82 ± 1.73 <i>vs</i> 2.31 ± 0.89; <i>P</i> < 0.001) and mean elastic modulus values (45.6 ± 15.8 kPa <i>vs</i> 21.3 ± 8.4 kPa; <i>P</i> < 0.001) than benign tumors. The optimal cutoff values were 3.45 for the strain ratio (sensitivity: 84.5%, specificity: 86.7%) and 32.5 kPa for the mean elastic modulus (sensitivity: 87.9%, specificity: 88.9%). The areas under the curve were 0.892 and 0.918, respectively. Interobserver agreement was excellent for both SE [intraclass correlation coefficient (ICC) = 0.88] and SWE (ICC range: 0.85-0.93) measurements.</p><p><strong>Conclusion: </strong>Ultrasound elastography shows high diagnostic accuracy in distinguishing between benign and malignant GISTs. Combining SE and SWE provides complementary parameters for preoperative risk stratification.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 6","pages":"103674"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction note: Efficacy and safety analysis of transarterial chemoembolization and transarterial radioembolization in advanced hepatocellular carcinoma descending hepatectomy.","authors":"Rui Feng, De-Xin Cheng, Tao Song, Long Chen, Kai-Ping Lu","doi":"10.4240/wjgs.v17.i5.105113","DOIUrl":"10.4240/wjgs.v17.i5.105113","url":null,"abstract":"<p><p>[This retracts the article on p. 687 in vol. 15, PMID: 37206075.].</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 5","pages":"105113"},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic ultrasound-guided pancreatic duct drainage: Progress and future outlook.","authors":"Si-Yao Wang, Si-Qiao Zhao, Shu-Peng Wang, Yue Zhang, Si-Yu Sun, Sheng Wang","doi":"10.4240/wjgs.v17.i5.104267","DOIUrl":"10.4240/wjgs.v17.i5.104267","url":null,"abstract":"<p><p>As an innovative endoscopic intervention, endoscopic ultrasound-guided pancreatic duct drainage (EUS-PD) demonstrates significant clinical value in resolving pancreatic ductal hypertension syndrome. By integrating real-time ultrasound guidance with catheter-based intervention techniques, this approach provides a safe and effective alternative for cases where conventional endoscopic retrograde cholangiopancreatography has failed. Current evidence indicates that EUS-PD achieves technical success rates ranging from 82% to 95% in alleviating symptomatic pancreatic duct hypertension caused by malignant obstructions and chronic pancreatitis-related strictures, with an overall complication rate (15%-20%) substantially lower than surgical interventions. Compared to conventional imaging modalities, EUS-PD offers superior anatomical visualization capabilities: Its high-frequency ultrasound probe enables precise identification of 3 mm-level pancreatic duct branches, while contrast-enhanced imaging significantly improves diagnostic accuracy in differentiating benign from malignant strictures (sensitivity 91% <i>vs</i> 73%, <i>P</i> < 0.05). Nevertheless, technical challenges persist, including difficult ductal puncture localization (particularly in pancreatic head lesions), complex guidewire axial control, and postoperative pancreatic fistula risks (7%-12%). This review systematically examines the clinical indications/contraindications, procedural protocols, device selection criteria, and management strategies for early/late complications associated with EUS-PD. Special emphasis is placed on establishing anatomical pathway selection standards for transgastric-pancreatic duct <i>vs</i> transduodenal-pancreatic duct approaches. Advancements in auxiliary technologies (<i>e.g.</i>, three-dimensional elastography, AI-assisted navigation) and multidisciplinary team collaboration are pivotal to developing standardized protocols. We propose establishing international multicenter registry databases and conducting prospective randomized controlled trials to clarify EUS-PD's position within pancreatic disease management systems. Such initiatives will facilitate the clinical transformation of EUS-PD from an \"alternative option\" to a \"preferred strategy\", ultimately enhancing treatment precision and improving clinical outcomes in pancreatic disorders.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 5","pages":"104267"},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing postoperative complications in patients with gastric cancer: A retrospective study.","authors":"Ying Xiao, Bang-Chun Ren, Tao Zhang, Dong Peng, Jiang Min","doi":"10.4240/wjgs.v17.i5.101047","DOIUrl":"10.4240/wjgs.v17.i5.101047","url":null,"abstract":"<p><strong>Background: </strong>Gastric cancer is a malignancy with high morbidity and mortality rates. Surgical intervention, particularly gastrectomy, is essential for curative treatment but carries a substantial risk of complications. Identifying key risk factors and understanding complication profiles are crucial for improving outcomes and guiding perioperative management.</p><p><strong>Aim: </strong>To analyze the incidence of postoperative complications in patients with gastric cancer and identify potential risk factors.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 500 patients who underwent gastrectomy between January 2018 and December 2022. Postoperative complications were classified using the Clavien-Dindo system.</p><p><strong>Results: </strong>The overall complication rate was 28.4% (142/500), with 15.2% (76/500) experiencing major complications (Clavien-Dindo grade ≥ III). Pulmonary complications were the most frequent (10.8%), followed by surgical site infections (8.6%), and anastomotic leakage (4.2%). Age 70 years or more, body mass index of 25 kg/m² or more, advanced tumor stage, total gastrectomy, and operative time 240 min or more emerged as independent risk factors.</p><p><strong>Conclusion: </strong>Focused preoperative risk assessment, targeted interventions, and reduced operative time for older or obese patients requiring total gastrectomy or presenting with advanced disease are important to improve surgical outcomes.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 5","pages":"101047"},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic abdominal pain caused by foreign bodies in the appendix: A case report.","authors":"Tao Huang, Shang-Kun Li, Wei Wang, Rui Zhang","doi":"10.4240/wjgs.v17.i5.105423","DOIUrl":"10.4240/wjgs.v17.i5.105423","url":null,"abstract":"<p><strong>Background: </strong>Acute abdominal pain is often easy to be diagnosed because of acute abdomen, and can be treated reasonably and effectively. It is more difficult to establish the cause of chronic abdominal pain, and some patients repeatedly visit several hospitals and still cannot be diagnosed. Chronic abdominal pain caused by chronic appendicitis is such a case. If the degree of abdominal pain is mild and there is no sign of peritonitis, chronic appendicitis is not performed unless the patient requests it.</p><p><strong>Case summary: </strong>We report an extremely rare case of chronic appendicitis caused by a foreign body in the appendix in a 35-year-old woman. The patient had a long-term abdominal pain of unclear cause, and she was repeatedly treated in several hospitals. After antibiotic treatment, the abdominal pain was gradually relieved, but abdominal pain often recurs. We conducted abdominal computed tomography examination, and upon the advice of radiologists, we considered the possibility of foreign bodies in the appendix, and excluded other causes of abdominal pain. The patient requested and consented to laparoscopic appendectomy, and a chicken bone was found in the appendiceal cavity by postoperative incision of the appendiceal specimen. Histopathological examination confirmed chronic appendicitis with foreign body giant cell reaction. The patient recovered and was discharged from the hospital. After 2 months of follow-up, abdominal pain did not recur, and the patient had a complete recovery.</p><p><strong>Conclusion: </strong>Surgery can relieve chronic abdominal pain caused by foreign bodies in the appendix, but only if it is diagnosed.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 5","pages":"105423"},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}