World Journal of Gastrointestinal Surgery最新文献

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Advancements in hepatic haemangioma surgery: An update-review of protocols, techniques, and postoperative outcomes. 肝血管瘤手术的进展:方案、技术和术后结果的最新综述。
IF 2.1 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-02-27 DOI: 10.4240/wjgs.v18.i2.116957
Sofia Rozani, Vasileios Vougas
{"title":"Advancements in hepatic haemangioma surgery: An update-review of protocols, techniques, and postoperative outcomes.","authors":"Sofia Rozani, Vasileios Vougas","doi":"10.4240/wjgs.v18.i2.116957","DOIUrl":"10.4240/wjgs.v18.i2.116957","url":null,"abstract":"<p><p>Hepatic haemangiomas are the most common benign liver lesions, often found on incidental imaging. Although often asymptomatic, they can lead to abdominal pain, bleeding and rarely rupture. Surgery is indicated in symptomatic cases or in case of complications. To evaluate current surgical management strategies for hepatic haemangiomas, focusing on recent advances in minimally invasive and robotic surgery, imaging, embolization, and perioperative care. It also explores the emerging role of artificial intelligence (AI) in preoperative planning, intraoperative guidance, and postoperative monitoring, and proposes evidence-based management algorithms reflecting current practice and future directions. This minireview synthesizes the recent literature on the surgical management of hepatic haemangiomas, with emphasis on advances in surgical strategies, perioperative protocols available to date, and postoperative care. The contemporary role of diagnostic imaging and AI in improving preoperative evaluation is also explored. Advances in minimally invasive techniques, improved intraoperative navigation and improved recovery protocols have significantly reduced surgical morbidity. The integration of AI has improved lesion characterization and surgical planning. Current surgical procedures, such as laparoscopic incision and robot-assisted resections, have demonstrated favorable outcomes in selected patients.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 2","pages":"116957"},"PeriodicalIF":2.1,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12968686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147435978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Augmented intelligence in "robotic" liver surgery: Integrating augmented reality and artificial intelligence for real-time navigation and margin precision. “机器人”肝脏手术中的增强智能:整合增强现实和人工智能,实现实时导航和边缘精度。
IF 2.1 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-02-27 DOI: 10.4240/wjgs.v18.i2.116351
Sofia Rozani
{"title":"Augmented intelligence in \"robotic\" liver surgery: Integrating augmented reality and artificial intelligence for real-time navigation and margin precision.","authors":"Sofia Rozani","doi":"10.4240/wjgs.v18.i2.116351","DOIUrl":"10.4240/wjgs.v18.i2.116351","url":null,"abstract":"<p><p>\"Robotic\" liver surgery has revolutionized minimally invasive hepatectomy, offering superior dexterity and visualization, but achieving accurate intraoperative navigation and safe resection margins remains difficult, especially for deep or posterior hepatocellular carcinomas. The convergence of augmented reality (AR) and artificial intelligence (AI), collectively described as augmented intelligence, is emerging as a transformative approach. We review the current evidence and future prospects of AR- and AI-assisted \"robotic\" liver surgery, focusing on their role in real-time anatomical guidance and margin control. Recent developments allow for real-time overlay of 3D reconstructions of the liver and segmentation of tumors and vascular structures, facilitating dynamic visualization and intraoperative decision-making. However, surgical and anatomical challenges, for instance, organ deformation, registration errors, and the lack of standardized protocols, limit its widespread adoption. Augmented intelligence represents the next frontier in \"robotic\" liver surgery, offering a path toward safer, more personalized, and data-driven hepatectomies.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 2","pages":"116351"},"PeriodicalIF":2.1,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12968691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147435437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of primary tumor site in surgery for colorectal liver metastases. 原发肿瘤部位在结直肠肝转移手术中的预后价值。
IF 2.1 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-02-27 DOI: 10.4240/wjgs.v18.i2.115622
Felix Pius Omullo
{"title":"Prognostic value of primary tumor site in surgery for colorectal liver metastases.","authors":"Felix Pius Omullo","doi":"10.4240/wjgs.v18.i2.115622","DOIUrl":"10.4240/wjgs.v18.i2.115622","url":null,"abstract":"<p><p>The compelling study by Liu <i>et al</i> delivers a critical verdict: The primary tumor site is not merely an anatomical detail, but a fundamental prognostic imperative in the surgical management of colorectal liver metastases. Their analysis of 178 patients definitively establishes right-sided colonic origin as an independent harbinger of aggressive disease, characterized by significantly higher recurrence rates and inferior survival outcomes compared to left-sided and rectal cancers. This biological dichotomy is further elucidated by the strong association of right-sided tumors with an adverse prognostic profile, including rampant lymph node metastasis, elevated D-dimer (reflecting a pro-thrombotic, pro-metastatic state), hypoalbuminemia, and resistance to neoadjuvant therapy. These findings necessitate an immediate paradigm shift in clinical practice. We can no longer treat colorectal cancer as a monolith. Preoperative risk stratification, surgical decision-making, and adjuvant therapy plans must be tailored according to the primary tumor location. For patients with right-sided primaries, these data suggest a more aggressive multimodal approach and vigilant, personalized surveillance to improve upon the discouraging outcomes this study clearly exposes.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 2","pages":"115622"},"PeriodicalIF":2.1,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12968685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of quality of life and reflux oesophagitis following Billroth II and Roux-en-Y gastrointestinal reconstruction for gastric cancer. 胃癌患者Billroth和Roux-en-Y胃肠重建术后的生活质量和反流性食管炎分析。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.114164
Xin-Xing Duan, Xiong Yu, Jin Gan
{"title":"Analysis of quality of life and reflux oesophagitis following Billroth II and Roux-en-Y gastrointestinal reconstruction for gastric cancer.","authors":"Xin-Xing Duan, Xiong Yu, Jin Gan","doi":"10.4240/wjgs.v18.i1.114164","DOIUrl":"10.4240/wjgs.v18.i1.114164","url":null,"abstract":"<p><strong>Background: </strong>The choice between Billroth II and Roux-en-Y reconstruction after radical gastrectomy for gastric cancer (GC) affects the occurrence of reflux and the quality of life (QoL) in patients.</p><p><strong>Aim: </strong>To investigate the QoL and reflux oesophagitis incidence in patients who underwent Billroth II or Roux-en-Y gastrointestinal reconstruction after radical gastrectomy for GC.</p><p><strong>Methods: </strong>One hundred patients with GC who underwent radical resection at our hospital between January 2023 and December 2024 were enrolled. The patients were divided into two groups based on the postoperative gastrointestinal reconstruction technique: The Billroth II group and the Roux-en-Y group, comprising 50 patients each. The incidence of gastroesophageal reflux within two weeks postoperatively was compared between the groups, including 24-hour reflux episodes, frequency of reflux episodes lasting > 5 minutes, and maximum reflux duration. The reflux symptom scores were measured. Nutritional indicators, including serum albumin (ALB), prealbumin (PA), and haemoglobin (Hb), were assessed 4 and 8 weeks postoperatively. The QoL was evaluated using the QLQ-C30 questionnaire. The incidence of reflux oesophagitis was monitored at 3 months of follow-up.</p><p><strong>Results: </strong>No significant differences were observed between the groups in terms of baseline clinical characteristics (<i>P</i> > 0.05). At 2 weeks postoperatively, the Roux-en-Y group exhibited significantly lower 24-hour reflux episodes, episodes lasting > 5 minutes, and maximum reflux duration than the Billroth II group (<i>P</i> < 0.05). The Roux-en-Y group exhibited significantly lower reflux symptom scores, including epigastric burning, acid regurgitation, upper abdominal distension, and upper abdominal pain, than the Billroth II group (<i>P</i> < 0.05). No significant differences were observed in the peripheral blood ALB, PA, or Hb levels at 4 and 8 weeks postoperatively between the two groups (<i>P</i> > 0.05). The QLQ-C30 scores at 4 and 8 weeks postoperatively were significantly higher in the Roux-en-Y group than in the Billroth II group (<i>P</i> < 0.05). At the 3-month postoperative follow-up, the incidence of reflux oesophagitis was 4.0% in the Roux-en-Y group, significantly lower than the 16.0% observed in the Billroth II group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Among patients with GC undergoing gastrointestinal reconstruction, Roux-en-Y procedures resulted in fewer cases of gastroesophageal reflux and milder symptoms than Billroth II procedures. Nutritional status was comparable postoperatively between the two reconstruction techniques. However, the former significantly affects the patients' QoL less favourably and exhibits a lower incidence of reflux oesophagitis, demonstrating considerable clinical significance.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"114164"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis of bile duct metastasis from gastric cancer by endoscopic retrograde cholangiopancreatography combined with choledochoscopy: A case report. 内镜逆行胆管造影联合胆道镜诊断胃癌胆管转移1例。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.112416
Cheng-Kun Li, Rong-Rong Cao, Dong-Shuai Su, Jian Ming, Ying-Chun Li, Xiao-Dong Shao, Xing-Shun Qi
{"title":"Diagnosis of bile duct metastasis from gastric cancer by endoscopic retrograde cholangiopancreatography combined with choledochoscopy: A case report.","authors":"Cheng-Kun Li, Rong-Rong Cao, Dong-Shuai Su, Jian Ming, Ying-Chun Li, Xiao-Dong Shao, Xing-Shun Qi","doi":"10.4240/wjgs.v18.i1.112416","DOIUrl":"10.4240/wjgs.v18.i1.112416","url":null,"abstract":"<p><strong>Background: </strong>Bile duct metastasis from gastric cancer is a very rare secondary cancer, which can cause biliary obstruction.</p><p><strong>Case summary: </strong>A 42-year-old male presented with right upper abdominal discomfort and jaundice after a total gastrectomy for poorly differentiated gastric adenocarcinoma. He underwent comprehensive laboratory tests and imaging examinations, and ultimately endoscopic retrograde cholangiopancreatography with choledochoscopy was performed. Stenoses were identified in the common hepatic duct and the common bile duct. Under choledochoscopic guidance, biopsy was taken from the bile duct tissue at the stenotic site. Then, a plastic stent was placed across the stenosis. Pathological examination with immunohistochemical staining confirmed poorly differentiated adenocarcinoma of the common bile duct. Following the procedure, the patient's liver function gradually improved, and his abdominal discomfort was also relieved.</p><p><strong>Conclusion: </strong>This case indicates the possibility of bile duct metastasis from gastric cancer and highlights the necessity of endoscopic retrograde cholangiopancreatography combined with choledochoscopy in patients with suspicious malignant biliary obstruction.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"112416"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anorectal changes and clinical outcomes after the Duhamel operation. Duhamel手术后肛肠的改变及临床结果。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.115171
Gokhan Demirtas, Gunay Ekberli, Huseyın Tugrul Tiryaki
{"title":"Anorectal changes and clinical outcomes after the Duhamel operation.","authors":"Gokhan Demirtas, Gunay Ekberli, Huseyın Tugrul Tiryaki","doi":"10.4240/wjgs.v18.i1.115171","DOIUrl":"10.4240/wjgs.v18.i1.115171","url":null,"abstract":"<p><strong>Background: </strong>Surgery for Hirschsprung's disease (HD) generally results in a satisfactory outcome, but some patients continue to have bowel dysfunction. There are very few studies in the literature that compare the early and late clinical outcomes.</p><p><strong>Aim: </strong>To evaluate changes in anorectal function and clinical outcome with age in patients who underwent Duhamel operation (DO) for HD.</p><p><strong>Methods: </strong>Twenty-eight patients who had previously undergone DO to treat HD were invited to an outpatient clinic upon reaching adulthood to participate in follow-ups. The patients' clinical data from the early and mid-term follow-ups were evaluated retrospectively based upon the hospital records and datasets from previous studies. The functional outcome tests in adulthood included anorectal manometry, rectoanal inhibitory reflex, maximum anal resting pressure, and a questionnaire.</p><p><strong>Results: </strong>Among the patients that reached adulthood and underwent early and mid-term evaluations, only 10 responded to the invitation and attended. That study population was comprised of 8 males and 2 females, ranging in age from 19 years to 25 years, with an average of 21.57 years. The anorectal inhibitory reflex was abnormal in 6 of the patients (66.7%). While the rate of patients who were deemed clinically \"good\" at the early postoperative evaluation was 53%, that rate reached to 90% in the adult evaluation.</p><p><strong>Conclusion: </strong>Improvement correlated with age, while other anorectal manometric parameters were unchanged. Long-term adult follow-up is essential for objectively evaluating surgical outcomes and overall success.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"115171"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features of post-colonoscopy colorectal cancer and real-world multi-scale correlation analysis. 结肠镜后结直肠癌临床特征与现实世界多尺度相关分析。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.112954
Yuan Li, Chu-Yan Wang, Ya-Xin Li, Zhu-Jun Wu, Lin-Jie Guo
{"title":"Clinical features of post-colonoscopy colorectal cancer and real-world multi-scale correlation analysis.","authors":"Yuan Li, Chu-Yan Wang, Ya-Xin Li, Zhu-Jun Wu, Lin-Jie Guo","doi":"10.4240/wjgs.v18.i1.112954","DOIUrl":"10.4240/wjgs.v18.i1.112954","url":null,"abstract":"<p><strong>Background: </strong>Post-colonoscopy colorectal cancer (PCCRC) remains an important issue in endoscopic examination. This study investigates the clinical features of PCCRC and possible correlation factors.</p><p><strong>Aim: </strong>To explore clinical features of PCCRC and correlation factors.</p><p><strong>Methods: </strong>A retrospective cohort analysis enrolled patients diagnosed with colorectal cancer (CRC) <i>via</i> colonoscopy at West China Hospital, Sichuan University, between January 1, 2022, and December 30, 2024. Demographic data, tumor characteristics, endoscopic findings, and miss records were extracted from electronic medical records and telephone follow-ups. An exploratory analysis was performed to identify causes of missed diagnosis during endoscopy.</p><p><strong>Results: </strong>Among 5411 colonoscopies in 2047 CRC patients, 66 prior examinations (27 colonoscopies in 17 non-PCCRC patients; 39 colonoscopies in 25 PCCRC patients) failed to establish diagnosis. The overall miss rate was 1.2%, with a PCCRC rate of 0.7%. Compared to the non-PCCRC group, advanced age was significantly associated with PCCRC (<i>P</i> = 0.006). The most common location that occurred PCCRC was sigmoid colon. PCCRC cases had higher rate of prior CRC surgery (41.0%). For endoscopists, PCCRC cases with CRC surgery increased the risk of judgement error. Insertion time demonstrated a positive correlation with missed diagnosis risk, whereas withdrawal time exhibited a negative correlation.</p><p><strong>Conclusion: </strong>The incidence of PCCRC remains significant. Beyond tumor characteristics, endoscopist proficiency and procedural factors critically impact detection accuracy.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"112954"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study. 白细胞介素-8在结肠癌中的诊断价值:前瞻性病例对照研究。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.115444
Gizem Güneş, Esra Fırat Oğuz, Ilgaz Kayılıoğlu, Tolga Dinç
{"title":"Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study.","authors":"Gizem Güneş, Esra Fırat Oğuz, Ilgaz Kayılıoğlu, Tolga Dinç","doi":"10.4240/wjgs.v18.i1.115444","DOIUrl":"10.4240/wjgs.v18.i1.115444","url":null,"abstract":"<p><strong>Background: </strong>Interleukin-8 (IL-8), a pro-inflammatory chemokine, is implicated in angiogenesis, tumor growth, and metastasis. However, its diagnostic and prognostic significance in colorectal cancer remains unclear.</p><p><strong>Aim: </strong>To evaluate the diagnostic utility of serum IL-8 in patients with newly diagnosed colon adenocarcinoma.</p><p><strong>Methods: </strong>In this prospective case-control study, 44 treatment-naïve patients with colon adenocarcinoma and 44 age-matched healthy controls were enrolled. Preoperative serum IL-8 levels were measured by enzyme-linked immunosorbent assay. Statistical analyses included univariate and multivariate models, odds ratios, and receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>Serum IL-8 levels were significantly higher in patients than in controls (<i>P</i> = 0.005). ROC curve analysis yielded an area under the curve of 0.68, with both sensitivity and specificity of 63.6% at a cut-off value of 42.3 ng/L. Multivariate analysis confirmed IL-8 as an independent predictor (odds ratio = 1.050), with each 1 ng/L increase conferring a 5% higher risk. No significant associations were observed with tumor stage, location, or histopathological features.</p><p><strong>Conclusion: </strong>IL-8 may serve as a diagnostic biomarker in colon adenocarcinoma, and its potential prognostic role warrants validation in larger, multicenter cohorts.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"115444"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gallbladder small cell carcinoma from chronic cholecystitis: A case report and review of literature. 慢性胆囊炎致胆囊小细胞癌1例并文献复习。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.114477
Jia-Qi Yu, Xue-Song He, Yu-Zhe Xue, Ling-Yu Hu, Xu Wen, Xiao-Dan Yang, Xue Zhou
{"title":"Gallbladder small cell carcinoma from chronic cholecystitis: A case report and review of literature.","authors":"Jia-Qi Yu, Xue-Song He, Yu-Zhe Xue, Ling-Yu Hu, Xu Wen, Xiao-Dan Yang, Xue Zhou","doi":"10.4240/wjgs.v18.i1.114477","DOIUrl":"10.4240/wjgs.v18.i1.114477","url":null,"abstract":"<p><strong>Background: </strong>Chronic calculous cholecystitis (CCC), caused by persistent gallstone-induced inflammation, can lead to development of small cell neuroendocrine carcinoma (SCNEC) of the gallbladder through chronic irritation, cellular damage, and repair. This report describes a rare case of advanced SCNEC of the gallbladder potentially induced by CCC and highlights its clinical features and treatment challenges.</p><p><strong>Case summary: </strong>A 64-year-old woman with a history of CCC presented with persistent right upper quadrant pain. Imaging revealed a mass in the gallbladder and hepatic hilum. The patient underwent radical cholecystectomy and hepatic resection. Histopathological examination confirmed SCNEC with synaptophysin and CD56 positivity and Ki-67 of 80%. Due to severe hepatic dysfunction (total bilirubin ≥ 300 μmol/L, albumin ≤ 25 g/L), chemotherapy was contraindicated. The patient's condition deteriorated rapidly, and she died 2 months postoperatively.</p><p><strong>Conclusion: </strong>Early detection and surgical intervention are critical for improving outcomes in gallbladder SCNEC associated with chronic inflammation.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"114477"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early gastric dilation after laparoscopic sleeve gastrectomy: Insights from a three-dimensional computed tomography reconstruction study. 腹腔镜袖胃切除术后早期胃扩张:来自三维计算机断层重建研究的见解。
IF 1.7 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2026-01-27 DOI: 10.4240/wjgs.v18.i1.112251
Zhao Li, Wen-Zhi Wu, Yi Song, Zhao-Peng Li, Dong Guo, Yu Li
{"title":"Early gastric dilation after laparoscopic sleeve gastrectomy: Insights from a three-dimensional computed tomography reconstruction study.","authors":"Zhao Li, Wen-Zhi Wu, Yi Song, Zhao-Peng Li, Dong Guo, Yu Li","doi":"10.4240/wjgs.v18.i1.112251","DOIUrl":"10.4240/wjgs.v18.i1.112251","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic sleeve gastrectomy (LSG) is currently the most commonly performed bariatric surgery owing to its effective weight loss and low complication rates. Nonetheless, some patients experience weight regain or insufficient weight loss due to residual gastric dilation, the factors of which remain unclear.</p><p><strong>Aim: </strong>To evaluate changes in residual gastric volume after LSG using three-dimensional computed tomography reconstruction and to investigate the factors contributing to gastric dilation.</p><p><strong>Methods: </strong>This retrospective study included 50 patients who underwent LSG. Preoperative clinical and laboratory data were obtained. The residual gastric volume was measured using three-dimensional computed tomography reconstruction at 1 month and 3 months postoperatively. The total sleeve volume, tube volume, antral volume, and tube-to-antral volume ratio were also assessed. Resected gastric volume and staple line length were measured during surgery. Weight metrics and laboratory indices were recorded at 1 month, 3 months, 6 months, and 12 months postoperatively. The Eating Behavior After Bariatric Surgery Questionnaire and Gastroesophageal Reflux Disease Questionnaire (GERD-Q) were used to assess the dietary behavior of patients after LSG. Correlation between the degree of residual gastric dilation and percent total weight loss (%TWL) at 12 months postoperatively was analyzed. Univariate and multivariate correlation analyses were conducted to identify risk factors for residual gastric dilation after LSG.</p><p><strong>Results: </strong>The 50 included patients had a mean preoperative body mass index of 42.27 ± 7.19 kg/m<sup>2</sup> and average %TWL of 34% ± 7% at 1 year after LSG. At 1 month after LSG, the mean tube volume, antral volume, and total sleeve volume were 45.93 ± 16.75 mL, 115.85 ± 44.92 mL, and 161.77 ± 55.37 mL, respectively. At 3 months after LSG, the residual gastric volume showed statistically significant dilation (average dilation degree: 13.50% ± 17.35%). %TWL at 1 year significantly correlated with residual gastric dilation (<i>P</i> < 0.05). Univariate and multivariate linear regression analyses revealed that preoperative type 2 diabetes, residual gastric volume at 1 month after LSG, and GERD-Q scores were independent risk factors influencing the degree of residual gastric dilation.</p><p><strong>Conclusion: </strong>In conclusion, residual gastric dilation after LSG significantly affected the efficacy of weight loss. Preoperative type 2 diabetes, residual gastric volume at 1 month after LSG, and GERD-Q scores were independent risk factors affecting the degree of residual gastric dilation.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"18 1","pages":"112251"},"PeriodicalIF":1.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12898905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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