World Journal of Gastrointestinal Surgery最新文献

筛选
英文 中文
Perioperative chemotherapy strategies in diffuse gastric cancer.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.101326
Niloufar Salehi, Maria Alqamish, Rasa Zarnegar
{"title":"Perioperative chemotherapy strategies in diffuse gastric cancer.","authors":"Niloufar Salehi, Maria Alqamish, Rasa Zarnegar","doi":"10.4240/wjgs.v17.i1.101326","DOIUrl":"10.4240/wjgs.v17.i1.101326","url":null,"abstract":"<p><p>This study reviews the findings of a recent study by Li <i>et al</i>, which demonstrated that perioperative chemotherapy benefits patients with diffuse-type gastric cancer compared to surgery alone. Despite potential biases, the study supports the inclusion of perioperative chemotherapy in treatment guidelines. Neoadjuvant and adjuvant chemotherapy may also provide similar survival outcomes, allowing for flexible treatment planning.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"101326"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of clinical efficacy of laparoscopic proximal gastrectomy with double-channel anastomosis and tubular gastroesophageal anastomosis.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.101204
Mian Wang, Li-Li Zhang, Gang Wang, Yong-Chang Miao, Tao Zhang, Lei Qiu, Gui-Da Fang, Feng Lu, Da-Lai Xu, Peng Yu
{"title":"Comparative study of clinical efficacy of laparoscopic proximal gastrectomy with double-channel anastomosis and tubular gastroesophageal anastomosis.","authors":"Mian Wang, Li-Li Zhang, Gang Wang, Yong-Chang Miao, Tao Zhang, Lei Qiu, Gui-Da Fang, Feng Lu, Da-Lai Xu, Peng Yu","doi":"10.4240/wjgs.v17.i1.101204","DOIUrl":"10.4240/wjgs.v17.i1.101204","url":null,"abstract":"<p><strong>Background: </strong>According to statistics, the incidence of proximal gastric cancer has gradually increased in recent years, posing a serious threat to human health. Tubular gastroesophageal anastomosis and double-channel anastomosis are two relatively mature anti-reflux procedures. A comparison of these two surgical procedures, tubular gastroesophageal anastomosis and double-channel anastomosis, has rarely been reported. Therefore, this study aimed to investigate the effects of these two reconstruction methods on the quality of life of patients with proximal gastric cancer after proximal gastrectomy.</p><p><strong>Aim: </strong>To compare short-term clinical results of laparoscopic proximal gastrectomy with double-channel anastomosis <i>vs</i> tubular gastric anastomosis.</p><p><strong>Methods: </strong>Patients who underwent proximal gastrectomy at our hospital between January 2020 and January 2023 were enrolled in this retrospective cohort study. The patients were divided into an experimental group (double-channel anastomosis, 33 cases) and a control group (tubular gastric anastomosis, 30 cases). Baseline characteristics, surgical data, postoperative morbidities, and postoperative nutrition were recorded.</p><p><strong>Results: </strong>The differences in baseline data, surgical data, and postoperative complications (20.0% <i>vs</i> 21.2%) were not statistically significant between the two groups. There were no statistically significant differences in the levels of postoperative nutrition indicators between the two groups of patients during the preoperative period and at 3 months postoperatively. In addition, the levels of postoperative nutrition indicators in patients in the experimental group declined significantly less at 6 months and 12 months postoperatively compared with those of the control group (<i>P</i> < 0.05). At 12 months postoperatively, the difference in anastomotic reflux esophagitis between the two groups was statistically significant (<i>P</i> < 0.05) with the experimental group showing less reflux esophagitis.</p><p><strong>Conclusion: </strong>Both double-channel anastomosis and tubular gastric anastomosis after proximal gastrectomy are safe and feasible. Double-channel anastomosis has a better anti-reflux effect and is more beneficial in improving the postoperative nutritional status.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"101204"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Five-year complete remission of super-giant hepatocellular carcinoma with hepatectomy followed by sorafenib plus camrelizumab: A case report.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.99752
Xiao-Qin Zheng, Li-Bo Sun, Wen-Jie Jin, Hui Liu, Wen-Yan Song, Hui Xu, Ju-Shan Wu, Xiao-Jun Wang, Chun-Yan Gou, Hui-Guo Ding
{"title":"Five-year complete remission of super-giant hepatocellular carcinoma with hepatectomy followed by sorafenib plus camrelizumab: A case report.","authors":"Xiao-Qin Zheng, Li-Bo Sun, Wen-Jie Jin, Hui Liu, Wen-Yan Song, Hui Xu, Ju-Shan Wu, Xiao-Jun Wang, Chun-Yan Gou, Hui-Guo Ding","doi":"10.4240/wjgs.v17.i1.99752","DOIUrl":"10.4240/wjgs.v17.i1.99752","url":null,"abstract":"<p><strong>Background: </strong>Cirrhotic patients with super-giant hepatocellular carcinoma (HCC) and portal vein invasion generally have a poor prognosis. This paper presents a patient with super-giant HCC and portal vein invasion, who underwent hepatectomy followed by a combination of sorafenib and camrelizumab, resulting in complete remission (CR) for 5 years.</p><p><strong>Case summary: </strong>A 40-year-old male with compensated hepatitis B-related cirrhosis was diagnosed with HCC, Barcelona Clinic Liver Cancer stage C. Enhanced computed tomography imaging revealed a 152 mm × 171 mm tumor in the right liver, invading the portal vein and hepatic vein. Liver function was normal. The patient successfully underwent hepatectomy on July 18, 2019. However, by December 2019, HCC recurrence with lung metastases and portal vein invasion were detected. He started treatment with sorafenib (200 mg twice daily) and camrelizumab (200 mg every 3 weeks). By May 12, 2020, the patient was confirmed to have CR. Camrelizumab was adjusted to 200 mg every 12 weeks from June 16, 2021, with the last infusion on March 29, 2024. Although no further tumor recurrence was observed, he experienced two episodes of gastrointestinal bleeding due to esophagogastric varices, which were managed with endoscopic therapy. To date, the patient has remained in CR for 5 years.</p><p><strong>Conclusion: </strong>The combination of hepatectomy with sorafenib and camrelizumab can achieve durable CR in patients with super-giant HCC and portal vein invasion. Further research is necessary to address these challenges and improve patient outcomes.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"99752"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence factors of clinical effects on patients with early gastric cancer: A retrospective study. 早期胃癌患者临床疗效的影响因素:回顾性研究
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.94873
Yong-Hua Zhang, Chao Ma, Xiao-Mei Huang, Yang Liu
{"title":"Influence factors of clinical effects on patients with early gastric cancer: A retrospective study.","authors":"Yong-Hua Zhang, Chao Ma, Xiao-Mei Huang, Yang Liu","doi":"10.4240/wjgs.v17.i1.94873","DOIUrl":"10.4240/wjgs.v17.i1.94873","url":null,"abstract":"<p><strong>Background: </strong>Identifying factors that influence non-curative resection (NCR) is critical to optimize treatment strategies and improve patient outcomes in patients with early gastric cancer (EGC).</p><p><strong>Aim: </strong>To investigate the factors influencing the NCR of EGC and to evaluate the predictive value of these factors.</p><p><strong>Methods: </strong>The clinical data of 173 patients with EGC admitted between July 2020 and July 2023 were retrospectively collected. According to radical resection criteria, the patients were further divided into curative resection group (<i>n</i> = 143) and NCR group (<i>n</i> = 30). Clinical information was collected, including surgical method, tumor diameter, tumor site, ulcer formation, depth of invasion, pathological type, and lymph node metastasis. Logistic regression analysis was used to explore the factors affecting non-curable resection.</p><p><strong>Results: </strong>Multivariate logistic regression analysis showed that ulcer formation [odds ratio (OR) = 3.53; 95% confidence interval (CI): 1.55-8.01, <i>P</i> = 0.003], pathological type (OR = 3.73; 95%CI: 1.60-8.74, <i>P</i> = 0.002), tumor diameter (OR = 3.15; 95%CI: 1.40-7.05, <i>P</i> = 0.005), tumor location (OR = 3.50; 95%CI: 1.16-10.58, <i>P</i> = 0.027), lymph node metastasis (OR = 4.40; 95%CI: 1.83-10.57, <i>P</i> = 0.001), and depth of penetration (OR = 3.75; 95%CI: 1.60-8.74, <i>P</i> = 0.002) were all risk factors for NCR in EGC patients. Predictive analysis showed varying area under the curve values for factors such as tumor diameter (0.636), tumor location (0.608), ulcer formation (0.652), infiltration depth (0.658), pathological type (0.656), and lymph node metastasis (0.674).</p><p><strong>Conclusion: </strong>The results suggest that factors such as tumor diameter, tumor location, ulcer formation, depth of invasion, pathological type, and lymph node metastasis increase the risk of NCR in EGC patients.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"94873"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating risk factors for surgical site infections and the effectiveness of prophylactic antibiotics in patients undergoing laparoscopic cholecystectomy.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.98567
Shao-Hua Wang
{"title":"Evaluating risk factors for surgical site infections and the effectiveness of prophylactic antibiotics in patients undergoing laparoscopic cholecystectomy.","authors":"Shao-Hua Wang","doi":"10.4240/wjgs.v17.i1.98567","DOIUrl":"10.4240/wjgs.v17.i1.98567","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections (SSIs) are a significant complication in laparoscopic cholecystectomy (LC), affecting patient outcomes and healthcare costs.</p><p><strong>Aim: </strong>To identify risk factors associated with SSIs and evaluate the effectiveness of prophylactic antibiotics in reducing these infections.</p><p><strong>Methods: </strong>A comprehensive retrospective evaluation was conducted on 400 patients who underwent LC from January 2022 to January 2024. Patients were divided into infected (<i>n</i> = 36) and non-infected (<i>n</i> = 364) groups based on the occurrence of SSIs. Data collected included age, diabetes mellitus status, use of prophylactic antibiotics, and specific surgical complications. Statistical analyses using SPSS (Version 27.0) involved univariate and multivariate logistic regression to determine factors influencing the risk of SSIs.</p><p><strong>Results: </strong>The use of prophylactic antibiotics significantly reduced the incidence of SSIs (<i>χ</i>² = 68.34, <i>P</i> < 0.01). Older age (≥ 60 years) and comorbidities such as diabetes mellitus were identified as significant risk factors. Surgical complications like insufficient cystic duct stump, gallbladder perforation, and empyema also increased SSI risk. Notably, factors such as intraoperative blood loss and operation time did not significantly impact SSI occurrence.</p><p><strong>Conclusion: </strong>Prophylactic antibiotics are effective in reducing the risk of SSIs in patients undergoing LC. Age, diabetes mellitus, and certain surgical complications significantly contribute to the risk. Effective management of these risk factors is essential to improve surgical outcomes and reduce the incidence of SSIs.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"98567"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of surgical strategy for low anterior resection syndrome using preoperative low anterior resection syndrome score in China.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.100910
Yang-Tao Pan, Yi-Min Lv, Shi-Chao Zhou, Dan-Yan Luo, Hao Sun, Wei-Feng Lao, Wei Zhou
{"title":"Evaluation of surgical strategy for low anterior resection syndrome using preoperative low anterior resection syndrome score in China.","authors":"Yang-Tao Pan, Yi-Min Lv, Shi-Chao Zhou, Dan-Yan Luo, Hao Sun, Wei-Feng Lao, Wei Zhou","doi":"10.4240/wjgs.v17.i1.100910","DOIUrl":"10.4240/wjgs.v17.i1.100910","url":null,"abstract":"<p><strong>Background: </strong>Despite improved survival rates in rectal cancer treatment, many patients experience low anterior resection syndrome (LARS). The preoperative LARS score (POLARS) aims to address the limitations of LARS assessment by predicting outcomes preoperatively to enhance surgical planning.</p><p><strong>Aim: </strong>To investigate the predictive accuracy of POLARS in assessing the occurrence of LARS.</p><p><strong>Methods: </strong>This study enrolled a total of 335 patients who underwent laparoscopic or robotic low anal sphincter-preserving surgery for rectal tumors. Patients were categorized into three groups according to their POLARS score: no LARS (score 0-20), minor LARS (score 21-29), and major LARS (score 30-42). The QLQ-C30/CR29 scores were compared among these groups, and the agreement between POLARS predictions and the actual LARS scores was analyzed.</p><p><strong>Results: </strong>The study population was divided into three groups: major LARS (<i>n</i> = 51, 27.42%), minor LARS (<i>n</i> = 109, 58.6%), and no LARS (<i>n</i> = 26, 13.98%). Significant differences in the QLQ-C30 scales of social function, diarrhea, and financial impact were detected between the no LARS and major LARS groups (<i>P</i> < 0.05) and between the minor LARS and major LARS groups (<i>P</i> < 0.05). Similarly, significant differences were detected in the QLQ-CR29 scales for blood and mucus in the stool, fecal incontinence, and stool frequency between the no LARS and minor LARS groups (<i>P</i> < 0.05), as well as between the minor LARS and major LARS groups (<i>P</i> < 0.05). The predictive precision for major LARS using the POLARS score was 82.35% (42/51), with a recall of 35.89% (42/117). The mean absolute error (MAE) between the POLARS score and the actual LARS score was 8.92 ± 5.47. In contrast, the XGBoost (extreme gradient boosting) model achieved a lower MAE of 6.29 ± 4.77, with a precision of 84.39% and a recall of 74.05% for predicting major LARS.</p><p><strong>Conclusion: </strong>The POLARS score demonstrated effectiveness and precision in predicting major LARS, thereby providing valuable insights into postoperative symptoms and patient quality of life. However, the XGBoost model exhibited superior performance with a lower MAE and higher recall for predicting major LARS compared to the POLARS model.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"100910"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple jejunal diverticula with repeated gastrointestinal bleeding: A case report.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.101623
Meng-Yun Li, Zhe Han, Hao Wang, Yuan-Yuan Wang, Zeng-Ren Zhao
{"title":"Multiple jejunal diverticula with repeated gastrointestinal bleeding: A case report.","authors":"Meng-Yun Li, Zhe Han, Hao Wang, Yuan-Yuan Wang, Zeng-Ren Zhao","doi":"10.4240/wjgs.v17.i1.101623","DOIUrl":"10.4240/wjgs.v17.i1.101623","url":null,"abstract":"<p><strong>Background: </strong>Jejunal diverticula (JD) are rare clinical conditions that are typically incidentally detected and asymptomatic. When acute complications arise, surgical exploration may be necessary for accurate diagnosis and appropriate treatment. In this report, we present a case of multiple JD complicated by gastrointestinal bleeding and review the pathogenesis, diagnosis, and treatment of JD to increase clinician awareness of this condition.</p><p><strong>Case summary: </strong>A 70-year-old male patient with multiple JD presented with repeated massive gastrointestinal bleeding. The patient did not respond to symptomatic conservative treatment. Additional diagnostic investigations, including digestive endoscopy and abdominal angiography, did not reveal any relevant abnormalities. An exploratory laparotomy was subsequently performed, during which a segment of the bowel containing numerous diverticulum-like structures was surgically removed. Following successful discharge from the hospital, the patient did not experience any further episodes of gastrointestinal bleeding during subsequent follow-up.</p><p><strong>Conclusion: </strong>Complications caused by JD are often difficult to diagnose, and surgical exploration is sometimes the most appropriate method.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"101623"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in liver retraction techniques for laparoscopic gastrectomy.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.101055
Andrew Daley, Ewen A Griffiths
{"title":"Advancements in liver retraction techniques for laparoscopic gastrectomy.","authors":"Andrew Daley, Ewen A Griffiths","doi":"10.4240/wjgs.v17.i1.101055","DOIUrl":"10.4240/wjgs.v17.i1.101055","url":null,"abstract":"<p><p>Traditionally, liver retraction for laparoscopic gastrectomy is done <i>via</i> manual methods, such as the placement of retractors through the accessory ports and using a Nathanson retractor. However, these techniques often posed issues including extra abdominal incisions, risk of liver injury or ischaemia, and the potential for compromised visualization. Over the years, the development of innovative liver retraction techniques has significantly improved the safety and efficacy of laparoscopic gastrectomy and similar other hiatal procedures. This editorial will comment on the article by Lin <i>et al</i>, and compare this to the other liver retractor techniques available for surgeons and highlight the pros and cons of each technique of liver retraction.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"101055"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic hepatectomy using indocyanine green attenuates postoperative inflammatory response for hepatocellular carcinoma: A propensity score matching analysis. 使用吲哚菁绿的腹腔镜肝切除术可减轻肝细胞癌术后炎症反应:倾向得分匹配分析。
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.101793
Wei-Xun Wu, Ming-Bin Huang, Mei-Xia Wang, Li-Hua Chen, Bo Hu, Zhen-Bin Ding
{"title":"Laparoscopic hepatectomy using indocyanine green attenuates postoperative inflammatory response for hepatocellular carcinoma: A propensity score matching analysis.","authors":"Wei-Xun Wu, Ming-Bin Huang, Mei-Xia Wang, Li-Hua Chen, Bo Hu, Zhen-Bin Ding","doi":"10.4240/wjgs.v17.i1.101793","DOIUrl":"10.4240/wjgs.v17.i1.101793","url":null,"abstract":"<p><strong>Background: </strong>Improving the intraoperative and postoperative performance of laparoscopic hepatectomy was quite a challenge for liver surgeons.</p><p><strong>Aim: </strong>To determine the benefits of indocyanine green (ICG) fluorescence imaging in patients with hepatocellular carcinoma (HCC) who underwent laparoscopic hepatectomy during and after surgery.</p><p><strong>Methods: </strong>We retrospectively collected the clinicopathological data of 107 patients who successfully underwent laparoscopic hepatectomy at Zhongshan Hospital (Xiamen), Fudan University from June 2022 to June 2023. Whether using the ICG fluorescence imaging technique, we divided them into the ICG and non-ICG groups. To eliminate statistical bias, a 1:1 propensity score matching analysis was conducted. The comparison of perioperative outcomes, including inflammation-related markers and progression-free survival, was analyzed statistically.</p><p><strong>Results: </strong>Intraoperatively, the ICG group exhibited lower blood loss, a shorter surgical time, lower hepatic inflow occlusion (HIO) frequency, and a shorter total HIO time. Postoperatively, the participation of ICG resulted in a shorter duration of hospitalization (6.5 <i>vs</i> 7.6 days, <i>P</i> = 0.03) and postoperative inflammatory response attenuation (lower neutrophil-lymphocyte ratio on the first day after surgery and platelet-lymphocyte ratio on the third day, <i>P</i> < 0.05). Although the differences were not significant, the levels of all inflammation-related markers were lower in the ICG group. The rates of postoperative complications and the survival analyses, including progression-free and overall survivals showed no significant difference between the groups.</p><p><strong>Conclusion: </strong>The involvement of ICG fluorescence imaging may lead to improved perioperative outcomes, especially postoperative inflammatory response attenuation, and ultimately improve HCC patients' recovery after surgery.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"101793"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rectal ameboma: A new entity in the differential diagnosis of rectal cancer.
IF 1.8 4区 医学
World Journal of Gastrointestinal Surgery Pub Date : 2025-01-27 DOI: 10.4240/wjgs.v17.i1.100278
Kemal Bugra Memis, Ayse Sena Celik, Sonay Aydin, Mecit Kantarci
{"title":"Rectal ameboma: A new entity in the differential diagnosis of rectal cancer.","authors":"Kemal Bugra Memis, Ayse Sena Celik, Sonay Aydin, Mecit Kantarci","doi":"10.4240/wjgs.v17.i1.100278","DOIUrl":"10.4240/wjgs.v17.i1.100278","url":null,"abstract":"<p><p>We examined the case report written by Ke <i>et al</i>, describing a rare clinical case. In this editorial, we would like to emphasize the differential diagnosis of rectal masses through a rare case. We describe a case of ameboma, which manifested itself as a mass in the rectum in terms of imaging and rectoscopic features, in an immunocompetent patient who had complaints of constipation and rectal bleeding for weeks. The initial diagnosis suggested malignancy due to imaging and rectoscopic features, but the pathology report reported it as amoebiasis. After ten days of metronidazole and oral amebicide (diloxanide furoate) treatment, the patient's symptoms and radiological findings were successfully regressed.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"17 1","pages":"100278"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信