Journal of the Japan Society of the Reticuloendothelial System最新文献_第5页

広範なinterdigitating reticulum cellsの増殖を伴った末梢型Tリンパ腫の一例伴随着广泛的interdigitating reticulum cells增殖的末梢型T淋巴瘤的一个例子

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.26.9

知子小嶋, 亮三浦, 昌宏斉藤, 勤綿貫, 琢松原, 荘治三浦, 道義菅原, 光子男鹿

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Myelodysplastic Symdrome Complicated by Malignant Lymphoma : Report of an Autopsy Case. 骨髓增生异常综合征并发恶性淋巴瘤1例尸检报告。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/jslrt1961.32.119

T. Kageyama, H. Morikawa, H. Ohyabu, T. Takubo, Y. Shibayama, K. Hashimoto, Ryuichi Yamamoto, K. Nakata

{"title":"Myelodysplastic Symdrome Complicated by Malignant Lymphoma : Report of an Autopsy Case.","authors":"T. Kageyama, H. Morikawa, H. Ohyabu, T. Takubo, Y. Shibayama, K. Hashimoto, Ryuichi Yamamoto, K. Nakata","doi":"10.3960/jslrt1961.32.119","DOIUrl":"https://doi.org/10.3960/jslrt1961.32.119","url":null,"abstract":"A case of myelodysplastic syndrome (MDS) complicated by malignant lymphoma is reported. The patient was a 68-year-old male who was admitted to hospital with severe anemia and was diagnosed as having MDS on the basis of hematological examinations and the findings of bone marrow biopsy. Treatment with steroid hormones, anabolic hormone preparations, and blood transfusion proved unsuccessful and he died of infection six months later.At autopsy, the bone marrow was hypoplastic and blast cells showed very poor differentiation, the megakaryocytes were decreased in number, and the erythroblasts had abnormal nuclei. Systemic lymphadenopathy (paratracheal, mesenteric, parapancreatic and paraaortic) was found. Histological examination of the lymph-nodes revealed diffuse proliferation of medium sized lymphocytes which had B cell markers and showed plasmacytoid differentiation.The starry sky constellation of large mononuclear phagocytes in the lymphoma tissue was quite similar to the histology of Burkitt's lymphoma. There was evidence of generalized cryptococcosis and candidiasis. Malignant lymphoma complicating MDS is very rare, but the exsistence of this case suggests that a clonal abnormality of the pluripotent hematopoietic stem cells occurs in MDS.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115164317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The Revised European-American Classification of Lymphoid Neoplasms: One Clinician's Comments. 修订的欧美淋巴肿瘤分类:一位临床医生的评论。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.36.139

K. Tobinai

{"title":"The Revised European-American Classification of Lymphoid Neoplasms: One Clinician's Comments.","authors":"K. Tobinai","doi":"10.3960/JSLRT1961.36.139","DOIUrl":"https://doi.org/10.3960/JSLRT1961.36.139","url":null,"abstract":"Characteristics, merits and some problems of the clinical relevance of the Revised European-American Lymphoma (REAL) classification are described, and the present status of research regarding is discussed. Several retrospective studies including pathologic reviews using the REAL system demonstrated that accurate diagnosis of newly incorporated categories such as mantle cell lymphoma and mucosaassociated lymphoid tissue (MALT)-lymphoma. was clinically significant, and that T-cell phenotype was an unfavorably prognostic factor on multivariate analysis. Although a considerable number of criticisms have been raised against the “REAL classification” such as the paucity of reproducibility studies, too many categories, lack of prognostic groupings, uncertain practicability in the patients whose immunophenotypic or molecular genetic data are not available, and questionable consensus among major hematopathologists, the REAL classification is still an attractive and probably useful classification, because each category is defined according to the presumed cell of origin, and the newly-incorporated categories are well described, using a combination of updated morphologic, immunologic, and genetic information. To evaluate the clinical implications of the REAL classification properly and establish useful clinical groupings, further clinicopathologic studies are needed.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115470449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The proliferation site of B-lymphocytes and the role of follicular dendritic cell in secondary lymphoid follicle of the tonsil. 扁桃体次级淋巴滤泡中b淋巴细胞的增殖部位及滤泡树突状细胞的作用。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.36.35

H. Orui, M. Yamakawa, Kazuhiko Yamada, T. Ogata, T. Tsunoda, T. Tsuge, K. Niino, Akihiko Suzuki, A. Suda, Yoshihiro Watanabe, F. Yuda, Y. Imai

{"title":"The proliferation site of B-lymphocytes and the role of follicular dendritic cell in secondary lymphoid follicle of the tonsil.","authors":"H. Orui, M. Yamakawa, Kazuhiko Yamada, T. Ogata, T. Tsunoda, T. Tsuge, K. Niino, Akihiko Suzuki, A. Suda, Yoshihiro Watanabe, F. Yuda, Y. Imai","doi":"10.3960/JSLRT1961.36.35","DOIUrl":"https://doi.org/10.3960/JSLRT1961.36.35","url":null,"abstract":"The proliferation site of B lymphocytes in secondary lymphoid follicle of the tonsil was evaluated. Five follicles were selected to detect histon H3 mRNA as marker of cells in S-phase of the cell cycle by in situ hybridization. Moreover, 11 follicles were selected and stained immunohistochemically with serial frozen sections with cyclin B1 as a G2-M phase marker, p34cdc2 as a marker mainly of G2-M phase, cyclin E as a marker mainly of late G1 phase, and Ki-67 as a marker of cells in the cell cycle. Secondary lymphoid follicles were divided into five zones by the HE stain and the expression of CD23 (Fc e receptor II) to calculate the positive rate of histon H3 mRNA and these proteins. The positive rates of histon H3 mRNA, cyclin B1, and p34cdc2 were the highest in the dark and the outer zones. The result implies that the outer zone as well as the dark zone is a proliferatation site of B cells.Nextly, the phase of the cell cycle of B cells in the follicular dendritic cell (FDC)-lymphocytes clusters, which were obtained from the germinal center of the secondary lymphoid follicle of human tonsils, is evaluated. The rate of cyclin B1-positive lymphocytes in the cluster (4.6%) is lower than that of the lymphocytes out of the cluster in germinal center (27.7%) and, moreover, the rate of Ki-67-positive cells in the cluster (35.9%) is lower than that of cells out of clusters (61.5%). The result shows that few G2-M phase lymphocytes are retained in the FDC-lymphocytes clusters and support that the B lymphocytes actively do not proliferate in the clusters.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123330578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abnormal functions of alveolar macrophages from patients with pulmonary sarcoidosis. 肺结节病患者肺泡巨噬细胞功能异常。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.30.39

Y. Nakata, M. Kataoka

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Detection of clonal B cell populations in paraffin-embedded tissues of primary gastric and thyroidal B-cell lymphoma using the polymerase chain reaction. 聚合酶链反应检测原发性胃和甲状腺B细胞淋巴瘤石蜡包埋组织中克隆B细胞群。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/jslrt1961.34.337

N. Yumoto, K. Kurosu, O. Ozaki, T. Mimura, Kunihiko Ito, M. Taniguchi, A. Mikata

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A new monoclonal antibody specific for human pre-B cell leukemia/lymphoma. 一种新的针对人b前细胞白血病/淋巴瘤的单克隆抗体。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.29.213

N. Nakamura

{"title":"A new monoclonal antibody specific for human pre-B cell leukemia/lymphoma.","authors":"N. Nakamura","doi":"10.3960/JSLRT1961.29.213","DOIUrl":"https://doi.org/10.3960/JSLRT1961.29.213","url":null,"abstract":"A new monoclonal antibody, designated WH14 antibody (WH14 Ab), was produced by using non-T ALL cell line (HBL-3 cell line) se an immunogen.HBL-3 cell line showed characteristics of the earliest B cell committed to B cell lineage [SIg-, CIg-. TdT+, Ia+, B4 (CD19)+, B1 (CD20)-, J5 (CD10-, IgHR, TcRG], HBL-3 cell line, according to the Nadler's or Foon's classification of non-T ALL, was representative for a pre-B cell of the Stage II.SDS-PAGE analysis of immunoprecipitates and Western blotting analysis revealed that the antigen reacting with WH14 was of molecule of 30, 000 daltons, Immunoglobulin isotype of WH14 Ab was IgGl.In the normal hematopoietic tissue, the WH14 Ab reacted with a small numbar of monocytes (<30%) and granulocytes (<2%) in the peripheral blood, but neither with lymphocytes in the lymph nodes and tonsils nor thymocytes in the thymus.WH14 Ab reacted with Non-T non-B cell ALL cell lines (REH) and pre-B cell line (HBL-3), but not with other B-cell leukemia/Iymphoma cell lines and EBV-transformed B cell lines.In addition, the WH14 Ab reactd with most non-T ALLs and B lymphoblastic lymphomas (SIg-, B4+, J5+) corresponding to pre-B cellderived neoplasm and some medium-sized cell lymphoma derived from intermediate-B cell, but not with other B-cell lymphoma.WH14 Ab didn't react with all T-cell lymphomas including ATLL. These findings indicated that the WH14 Ab might recognize the cell surface determinant shared by immature B cells, especially pre-B eclls in the B-cell lineage.WH14 Ab is useful for the study to analysis the characterization and difference of B cells in immature stage.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121698184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of primary splenic histiocytic sarcoma. 原发性脾组织细胞肉瘤1例。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.33.11

Y. Yamaguchi, K. Tasaki, N. Nakamura, M. Abe, H. Wakasa

{"title":"A case of primary splenic histiocytic sarcoma.","authors":"Y. Yamaguchi, K. Tasaki, N. Nakamura, M. Abe, H. Wakasa","doi":"10.3960/JSLRT1961.33.11","DOIUrl":"https://doi.org/10.3960/JSLRT1961.33.11","url":null,"abstract":"A case of primary splenic histiocytic sarcoma is reported.A 29-year-old man was admitted to Fukushima Medical College Hospital for pretibial edema. Physical examination showed splenomegaly without lymphadenopathy and hepatomegaly. Laboratory findings revealed thrombocytopenia and hypoproteinemia, and bone marrow aspirate and biopsy were normal. Clinically, splenic malignant lymphoma was suspected and surgical splenectomy was performed. His symptoms resolved after the treatment.The spleen weighed 730g and a well-defined reddish-colored tumor was observed on cut surface. The tumor was composed of an intense infiltration of variable sized histiocytic cells, from 8μm to 20μm in diameter, containing abundant eosinophilic cytoplasm and large round to oval nuclei.Mitotic figures were a few and multinuclated giant cells were occasionally seen. The tumor cells were considered as monocyte/histiocyte series based on cellular morphology and immunological charactaristics for monocytic markers and germline of immunogloblin heavy chain (JH) and T-cell recepter beta chain (Cβ1) genes. Flow-cytometric DNA analysis showed a hypodiploidy pattern. These findings indicate that the present case is primary splenic histiocytic sarcoma with low grade malignancy.","PeriodicalId":237003,"journal":{"name":"Journal of the Japan Society of the Reticuloendothelial System","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126263398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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An autopsy case of IgA .KAPPA. type multiple myeloma complicated with amyloidosis and crystalline immunoglobulin-accumulating histiocytoma. IgA . kappa尸检1例。型多发性骨髓瘤合并淀粉样变和结晶性免疫球蛋白积聚组织细胞瘤。

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.24.143

Kiyoshi Takahashi

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Monocytoid B Lymphocyteの増殖巣を伴う膿瘍形成性肉芽腫性リンパ節炎について关于Monocytoid blymphocyte的脓肿形成性肉芽肿性淋巴结炎

Journal of the Japan Society of the Reticuloendothelial System Pub Date : 1900-01-01 DOI: 10.3960/JSLRT1961.29.97

勝小島, 英昭石井, 秀明伊藤, 尚城下, 吉田カツ江, 滋之浅野, 治毅若狭, 泰山須知

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