Monocytoid B Lymphocyteの増殖巣を伴う膿瘍形成性肉芽腫性リンパ節炎について

Abstract

Forming granulomatous lymphadenitis with monocytoid B lymphocytes (MBL) foci was studied with special referance to the cat scratch disease (CSD)The 12 cases consisted of 8 male and 4 female, and their ages ranged from 8 to 53, and 4 had history of cat scratching and 1 had a trauma.Histologically, the lesion was comprised of suppurative granuloma, surrounded by layers of palisaded histiocytes. In addition to these findings, reactive follicular hyperplasia, multiple small clusters of epithelioid histiocytes and proliferating foci of MBL were recoginized in all cases.In 6 cases, pleomorphic bacteria were demonstrated with the Warthin-Starry silver stain. Toxoplasma and chlamydia were negative in all cases with immunoperoxidase method.These findings indicate that some cases of abscess forming granulomatous lymphadenitis with MBL would be included in CSD.