关于Monocytoid blymphocyte的脓肿形成性肉芽肿性淋巴结炎

勝 小島, 英昭 石井, 秀明 伊藤, 尚 城下, 吉田 カツ江, 滋之 浅野, 治毅 若狭, 泰山 須知
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引用次数: 0

摘要

对形成肉芽肿性淋巴结炎伴单细胞B淋巴细胞灶(MBL)进行研究,并特别参考猫抓病(CSD)。12例患者男8例,女4例,年龄8 ~ 53岁,4例有猫抓史,1例有外伤。组织学上,病变由化脓性肉芽肿组成,被栅栏状组织细胞层包围。除了这些发现外,所有病例还发现反应性滤泡增生,多个小上皮样组织细胞簇和MBL的增殖灶。6例经Warthin-Starry银染色证实为多形性细菌。免疫过氧化物酶法检测弓形虫和衣原体均阴性。这些结果表明,一些脓肿形成的肉芽肿性淋巴结炎合并MBL可能包括在CSD中。
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Monocytoid B Lymphocyteの増殖巣を伴う膿瘍形成性肉芽腫性リンパ節炎について
Forming granulomatous lymphadenitis with monocytoid B lymphocytes (MBL) foci was studied with special referance to the cat scratch disease (CSD)The 12 cases consisted of 8 male and 4 female, and their ages ranged from 8 to 53, and 4 had history of cat scratching and 1 had a trauma.Histologically, the lesion was comprised of suppurative granuloma, surrounded by layers of palisaded histiocytes. In addition to these findings, reactive follicular hyperplasia, multiple small clusters of epithelioid histiocytes and proliferating foci of MBL were recoginized in all cases.In 6 cases, pleomorphic bacteria were demonstrated with the Warthin-Starry silver stain. Toxoplasma and chlamydia were negative in all cases with immunoperoxidase method.These findings indicate that some cases of abscess forming granulomatous lymphadenitis with MBL would be included in CSD.
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